Associate Professor, Department of Pediatrics, Sections of Hospital Medicine and Infectious Diseases
Recognition & Awards
Top Doctor: Pediatric Infectious Diseases, 5280 Magazine
(2021)
Young Investigator Award, Pediatric Infectious Disease Society
(2021)
Presented annually to a single physician whose independent and productive research during and after fellowship represents outstanding contributions in pediatric infectious diseases
Top Doctor: Pediatric Infectious Diseases, 5280 Magazine
(2020)
Voted by licensed CO physicians
Top Doctor: Pediatric Infectious Diseases, 5280 Magazine
(2019)
Voted by licensed CO physicians
Top Doctor: Pediatric Infectious Diseases, 5280 Magazine
(2018)
Voted by licensed CO physicians
Century Award, Children's Hospital Colorado
(2018)
Recognizes a staff member with five or fewer years of training who has made major contributions through committee work, leadership and/or advocacy.
Acute Flaccid Myelitis Task Force, Centers for Disease Control and Prevention Board of Scientific Counselors
(2018)
https://www.cdc.gov/ddid/bsc/afm-task-force.html
Gary Way Award for Outstanding Teaching by a Faculty Member, University of Colorado Department of Pediatrics
(2017)
Elected by the University of Colorado pediatric residents
Top Doctor: Pediatric Infectious Diseases, 5280 Magazine
(2017)
Voted by licensed CO physicians
Research Scholars Award, Children's Hospital Colorado Research Institute
(2015)
Astute Clinician Award, Colorado Department of Public Health and Environment
(2014)
For initial description of the association of Acute Flaccid Myelitis and Enterovirus D68 in CO in 2014
Fellow Teaching Award, University of Colorado School of Medicine, Department of Pediatrics
(2013)
Voted by University of Colorado pediatric residents
Outstanding Resident of the Year, University of Colorado NICU
(2011)
Resident Teaching Award, University of Colorado School of Medicine, Department of Pediatrics
(2011)
Voted by University of Colorado medical students
Outstanding Intern of the Year, University of Colorado NICU
(2009)
MCAS Academic Achievement Award, University of Michigan Medical School
(2008)
Highest Academic Standing in the Graduating Class of 2008
Alpha Omega Alpha Medical Honors Society, Alpha Omega Alpha, University of Michigan Chapter
(2008)
Dean’s Commendation for Excellence in Clinical Skills and the Art of Medicine, University of Michigan Medical School
(2008)
Distinction in Service, University of Michigan Medical School
(2008)
Dean’s Merit Scholarship, University of Michigan Medical School
(2003)
Highest Distinction and Highest Honors in Biochemistry, University of Michigan
(2003)
My research interests include using new rapid tests to improve the care of children with infections. I am interested in learning more about what causes brain and spinal cord infections in children. I have been investigating the causes of acute flaccid myelitis, which causes paralysis in children, including enterovirus D68 and A71. I am seeking to improve our pandemic preparedness by studying ways to expedite the development of tools to respond to the next emerging infectious disease.
Teaching
Infectious Disease Rotation Coordinator
(2016)
School of Medicine,
Pediatrics
Evidence Based Clinical Effectiveness Conference Faculty Co-Facilitator
(2016)
School of Medicine,
Pediatrics
Publications
Ku TSN, Al Mohajer M, Newton JA, Wilson MH, Monsees E, Hayden MK, Messacar K, Kisgen JJ, Diekema DJ, Morgan DJ, Sifri CD, Vaughn VM. Improving antimicrobial use through better diagnosis: The relationship between diagnostic stewardship and antimicrobial stewardship. Infect Control Hosp Epidemiol. 2023 Sep 4;:1-8. [Epub ahead of print] PubMed PMID: 37665212
Park SY, Chang EJ, Ledeboer N, Messacar K, Lindner MS, Venkatasubrahmanyam S, Wilber JC, Vaughn ML, Bercovici S, Perkins BA, Nolte FS. Plasma Microbial Cell-Free DNA Sequencing from over 15,000 Patients Identified a Broad Spectrum of Pathogens. J Clin Microbiol. 2023 Aug 23;61(8):e0185522. PubMed PMID: 37439686
Nguyen-Tran H, Reno S, Mwangi E, Mentel M, Hengartner R, Dominguez SR, Messacar K, Jung SA. Qualitative detection of enterovirus D68 from PrimeStore® molecular transport medium: implications for home- and self-collection. Diagn Microbiol Infect Dis. 2023 Aug;106(4):115976. PubMed PMID: 37267740
Rao S, Armistead I, Messacar K, Alden NB, Schmoll E, Austin E, Dominguez SR. Shifting Epidemiology and Severity of Respiratory Syncytial Virus in Children During the COVID-19 Pandemic. JAMA Pediatr. 2023 Jul 1;177(7):730-732. PubMed PMID: 37184852
Le Maréchal M, Diaz-Arias LA, Beekmann SE, Polgreen P, Messacar K, Tunkel AR, Thakur KT, Venkatesan A. Perspectives on Diagnosis and Management of All-Cause Encephalitis: A National Survey of Adult Infectious Diseases Physicians. Open Forum Infect Dis. 2023 Apr;10(4):ofad132. PubMed PMID: 37125234
Boster JM, Dominguez SR, Messacar K, Adams M, Weinberg A, Black JO, Feldman AG. Acute Liver Failure in a Child With Adenovirus Detected by PCR in the Explanted Liver. Pediatrics. 2023 Feb 1;151(2). PubMed PMID: 36691756
Nguyen-Tran H, Thompson C, Butler M, Miller KR, Pyle L, Jung S, Routh J, Dominguez SR, Messacar K. Duration of Enterovirus D68 RNA Shedding in the Upper Respiratory Tract and Transmission Among Household Contacts. Emerging Infectious Diseases. 2023
Messacar K, Palmer C, Gregoire L, Elliott A, Ackley E, Perraillon MC, Tyler KL, Dominguez SR. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022 May;244:161-168.e1. PubMed PMID: 35150729
Nguyen-Tran H, Park SW, Messacar K, Dominguez SR, Vogt MR, Permar S, Permaul P, Hernandez M, Douek DC, McDermott AB, Metcalf CJE, Grenfell B, Spaulding AB. Enterovirus D68: a test case for the use of immunological surveillance to develop tools to mitigate the pandemic potential of emerging pathogens. Lancet Microbe. 2022 Feb;3(2):e83-e85. PubMed PMID: 35036969
Nguyen-Tran H, Messacar K. Preventing enterovirus A71 disease: another promising vaccine for children. Lancet. 2022 Apr 30;399(10336):1671-1673. PubMed PMID: 35427482
Messacar K, Baker RE, Park SW, Nguyen-Tran H, Cataldi JR, Grenfell B. Preparing for uncertainty: endemic paediatric viral illnesses after COVID-19 pandemic disruption. Lancet. 2022 Jul 14. [Epub ahead of print] PubMed PMID: 35843260
Messacar K, Baker RE, Park SW, Nguyen-Tran H, Cataldi JR, Grenfell B. Preparing for uncertainty: endemic paediatric viral illnesses after COVID-19 pandemic disruption. Lancet. 2022 Nov 12;400(10364):1663-1665. PubMed PMID: 35843260
Nguyen-Tran H, Messacar K. Preventing enterovirus A71 disease: another promising vaccine for children. Lancet. 2022 Apr 30;399(10336):1671-1673. PubMed PMID: 35427482
Messacar K, Palmer C, Gregoire L, Elliott A, Ackley E, Perraillon MC, Tyler KL, Dominguez SR. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022 May;244:161-168.e1. PubMed PMID: 35150729
Nguyen-Tran H, Park SW, Messacar K, Dominguez SR, Vogt MR, Permar S, Permaul P, Hernandez M, Douek DC, McDermott AB, Metcalf CJE, Grenfell B, Spaulding AB. Enterovirus D68: a test case for the use of immunological surveillance to develop tools to mitigate the pandemic potential of emerging pathogens. Lancet Microbe. 2022 Feb;3(2):e83-e85. PubMed PMID: 35036969
Messacar K, Baker RE, Park SW, Nguyen-Tran H, Cataldi JR, Grenfell B. Preparing for uncertainty: endemic paediatric viral illnesses after COVID-19 pandemic disruption. Lancet. 2022 Nov 12;400(10364):1663-1665. PubMed PMID: 35843260
Nguyen-Tran H, Messacar K. Preventing enterovirus A71 disease: another promising vaccine for children. Lancet. 2022 Apr 30;399(10336):1671-1673. PubMed PMID: 35427482
Messacar K, Palmer C, Gregoire L, Elliott A, Ackley E, Perraillon MC, Tyler KL, Dominguez SR. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022 May;244:161-168.e1. PubMed PMID: 35150729
Nguyen-Tran H, Park SW, Messacar K, Dominguez SR, Vogt MR, Permar S, Permaul P, Hernandez M, Douek DC, McDermott AB, Metcalf CJE, Grenfell B, Spaulding AB. Enterovirus D68: a test case for the use of immunological surveillance to develop tools to mitigate the pandemic potential of emerging pathogens. Lancet Microbe. 2022 Feb;3(2):e83-e85. PubMed PMID: 35036969
Dehority W, Janowski AB, Messacar K, Polgreen PM, Beekmann SE. Variability in the Use of Novel Diagnostic Technology in Children With Suspected Encephalitis and in the Management of Emerging Encephalitides by Pediatric Infectious Disease Providers. J Pediatric Infect Dis Soc. 2021 Apr 30;10(4):529-532. PubMed PMID: 33347568
Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA. Acute flaccid myelitis: cause, diagnosis, and management. Lancet. 2021 Jan 23;397(10271):334-346. PubMed PMID: 33357469
Park SW, Pons-Salort M, Messacar K, Cook C, Meyers L, Farrar J, Grenfell BT. Epidemiological dynamics of enterovirus D68 in the United States and implications for acute flaccid myelitis. Sci Transl Med. 2021 Mar 10;13(584). PubMed PMID: 33692131
Ackley ER, Tchou MJ, Press CA, Parker SK, Dominguez SR, Gaensbauer J, Messacar K. AKI In Suspected Meningitis/Encephalitis May Be "Avoidable Kidney Injury". Hosp Pediatr. 2021 Aug;11(8):e167-e169. PubMed PMID: 34244336
Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GM, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR. Author Correction: Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nat Med. 2021 Oct;27(10):1849. PubMed PMID: 34548659
Graff K, Dominguez SR, Messacar K. Metagenomic Next-Generation Sequencing for Diagnosis of Pediatric Meningitis and Encephalitis: A Review. J Pediatric Infect Dis Soc. 2021 Dec 24;10(Supplement_4):S78-S87. PubMed PMID: 34951470
Graff K, Dominguez SR, Messacar K. Metagenomic Next-Generation Sequencing for Diagnosis of Pediatric Meningitis and Encephalitis: A Review. J Pediatric Infect Dis Soc. 2021 Dec 24;10(Supplement_4):S78-S87. PubMed PMID: 34951470
Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GM, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR. Author Correction: Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nat Med. 2021 Oct;27(10):1849. PubMed PMID: 34548659
Ackley ER, Tchou MJ, Press CA, Parker SK, Dominguez SR, Gaensbauer J, Messacar K. AKI In Suspected Meningitis/Encephalitis May Be "Avoidable Kidney Injury". Hosp Pediatr. 2021 Aug;11(8):e167-e169. PubMed PMID: 34244336
Park SW, Pons-Salort M, Messacar K, Cook C, Meyers L, Farrar J, Grenfell BT. Epidemiological dynamics of enterovirus D68 in the United States and implications for acute flaccid myelitis. Sci Transl Med. 2021 Mar 10;13(584). PubMed PMID: 33692131
Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA. Acute flaccid myelitis: cause, diagnosis, and management. Lancet. 2021 Jan 23;397(10271):334-346. PubMed PMID: 33357469
Dehority W, Janowski AB, Messacar K, Polgreen PM, Beekmann SE. Variability in the Use of Novel Diagnostic Technology in Children With Suspected Encephalitis and in the Management of Emerging Encephalitides by Pediatric Infectious Disease Providers. J Pediatric Infect Dis Soc. 2021 Apr 30;10(4):529-532. PubMed PMID: 33347568
Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, Messer R, Maloney J, Burakoff A, Barnes M, Rogers S, Lopez AS, Routh J, Gerber SI, Oberste MS, Nix WA, Abzug MJ, Tyler KL, Herlihy R, Dominguez SR. Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study. Lancet Infect Dis. 2020 Feb;20(2):230-239. PubMed PMID: 31859216
Tran P, Dowell E, Hamilton S, Dolan SA, Messacar K, Dominguez SR, Todd J. Two Blood Cultures With Age-Appropriate Volume Enhance Suspected Sepsis Decision-Making. Open Forum Infect Dis. 2020 Feb;7(2):ofaa028. PubMed PMID: 32055641
Rao S, Martin J, Ahearn MA, Osborne C, Moss A, Dempsey A, Dominguez SR, Weinberg A, Messacar KB. Neurologic Manifestations of Influenza A(H3N2) Infection in Children During the 2016-2017 Season. J Pediatric Infect Dis Soc. 2020 Feb 28;9(1):71-74. PubMed PMID: 30590598
Gould CV, Messacar K, Dominguez SR, Panella A, Tobolowsky F, Fischer M. EVALUATION FOR ARBOVIRAL INFECTION AMONG CHILDREN HOSPITALIZED IN COLORADO WITH ASEPTIC MENINGITIS AND ENCEPHALITIS. Pediatr Infect Dis J. 2020 Aug 5. [Epub ahead of print] PubMed PMID: 32773665
Park SW, Farrar J, Messacar K, Meyers L, Pons-Salort M, Grenfell BT. Epidemiological dynamics of enterovirus D68 in the US: implications for acute flaccid myelitis. medRxiv. 2020 Jul 29. PubMed PMID: 32766605
Shah PV, Wathen J, Keyes J, Osborne C, Messacar K, Stence N, Kothari K. Foreign Body Esophageal Perforation Leading to Multifocal Brain Abscesses: A Case Report. J Emerg Med. 2020 Jul 18. [Epub ahead of print] PubMed PMID: 32694010
Murphy OC, Messacar K, Benson L, Bove R, Carpenter J, Crawford T, Dean J, Debiasi R, Desai J, Ellrick MJ, Farias-Moeller R, Gombolay RY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda KK, Hlefferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA. Acute Flaccid Myelitis: Etiology, diagnosis and management. The Lancet 2020 (accepted, in press)
Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, Messer R, Maloney J, Burakoff A, Barnes M, Rogers S, Lopez AS, Routh J, Gerber SI, Oberste MS, Nix WA, Abzug MJ, Tyler KL, Herlihy R, Dominguez SR. Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study. Lancet Infect Dis. 2020 Feb;20(2):230-239. PubMed PMID: 31859216
Messacar K, Gaensbauer JT, Birkholz M, Palmer C, Todd JK, Tyler KL, Dominguez SR. Impact of FilmArray meningitis encephalitis panel on HSV testing and empiric acyclovir use in children beyond the neonatal period. Diagn Microbiol Infect Dis. 2020 Aug;97(4):115085. PubMed PMID: 32559588
Gould CV, Messacar K, Dominguez SR, Panella A, Tobolowsky F, Fischer M. Evaluation for Arboviral Infection Among Children Hospitalized in Colorado With Aseptic Meningitis and Encephalitis. Pediatr Infect Dis J. 2020 Nov;39(11):e382-e384. PubMed PMID: 32773665
Fall A, Ndiaye N, Messacar K, Kebe O, Jallow MM, Harouna H, Kiori DE, Sy S, Goudiaby D, Dia M, Niang MN, Ndiaye K, Dia N. Enterovirus D68 Subclade B3 in Children with Acute Flaccid Paralysis in West Africa, 2016. Emerg Infect Dis. 2020 Sep;26(9):2227-2230. PubMed PMID: 32818390
Kirkley MJ, Robinson C, Dominguez SR, Messacar K. Neonatal parechovirus infection mimicking a surgical abdomen. BMJ Case Rep. 2019 Jun 26;12(6). PubMed PMID: 31248894
Olson CA, Dominguez SR, Miller S, Chiu CY, Messacar K. Gastroenteritis, Hepatitis, Encephalopathy, and Human Herpesvirus 6 Detection in an Immunocompetent Child: Benefits and Risks of Syndromic Multiplex Molecular Panel Testing. J Pediatr. 2019 Sep;212:228-231. PubMed PMID: 31208781
Christy A, Messacar K. Acute Flaccid Myelitis Associated With Enterovirus D68: A Review. J Child Neurol. 2019 Aug;34(9):511-516. PubMed PMID: 31014167
Messacar K, Pretty K, Reno S, Dominguez SR. Continued biennial circulation of enterovirus D68 in Colorado. J Clin Virol. 2019 Apr;113:24-26. PubMed PMID: 30825833
Messacar K, Tyler KL. Enterovirus D68-Associated Acute Flaccid Myelitis: Rising to the Clinical and Research Challenges. JAMA. 2019 Mar 5;321(9):831-832. PubMed PMID: 30768149
Messacar K, Abzug MJ, Dominguez SR. Acute Flaccid Myelitis Surveillance: A Signal Through the Noise. Pediatrics. 2019 Nov;144(5). PubMed PMID: 31591134
Gaensbauer JT, Todd J, Grubenhoff JA, Soranno DE, Scudamore D, Cheetham A, Messacar K. A Resident-Based, Educational Program to Drive Individual and Institutional Improvement in a Pediatric Training Hospital. J Pediatr. 2019 Nov;214:4-7.e1. PubMed PMID: 31655703
Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GA, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR. Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nat Med. 2019 Nov;25(11):1748-1752. PubMed PMID: 31636453
Miller S, Naccache SN, Samayoa E, Messacar K, Arevalo S, Federman S, Stryke D, Pham E, Fung B, Bolosky WJ, Ingebrigtsen D, Lorizio W, Paff SM, Leake JA, Pesano R, DeBiasi R, Dominguez S, Chiu CY. Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid. Genome Res. 2019 May;29(5):831-842. PubMed PMID: 30992304
Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis. Neurology. 2019 Apr 30;92(18):e2118-e2126. PubMed PMID: 30413631
Searns J, Cataldi JR, McCormack K, Simões E, Messacar K, Dominguez SR. A 4-Year-Old Boy With an Unusual Bacterial Meningitis Infection. J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):282-283. PubMed PMID: 30299497
Kane MS, Sonne C, Zhu S, Malhotra A, Van Haren K, Messacar K, Glaser CA. Incidence, Risk Factors and Outcomes Among Children With Acute Flaccid Myelitis: A Population-based Cohort Study in a California Health Network Between 2011 and 2016. Pediatr Infect Dis J. 2019 Jul;38(7):667-672. PubMed PMID: 30985511
Dubey D, Pittock SJ, Krecke KN, Morris PP, Sechi E, Zalewski NL, Weinshenker BG, Shosha E, Lucchinetti CF, Fryer JP, Lopez-Chiriboga AS, Chen JC, Jitprapaikulsan J, McKeon A, Gadoth A, Keegan BM, Tillema JM, Naddaf E, Patterson MC, Messacar K, Tyler KL, Flanagan EP. Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody. JAMA Neurol. 2019 Mar 1;76(3):301-309. PubMed PMID: 30575890
Elrick MJ, Gordon-Lipkin E, Crawford TO, Van Haren K, Messacar K, Thornton N, Dee E, Voskertchian A, Nance JR, Muñoz LS, Gorman MP, Benson LA, Thomas DL, Pardo CA, Milstone AM, Duggal P. Clinical Subpopulations in a Sample of North American Children Diagnosed With Acute Flaccid Myelitis, 2012-2016. JAMA Pediatr. 2019 Feb 1;173(2):134-139. PubMed PMID: 30500056
Hopkins SE, Elrick MJ, Messacar K. Acute Flaccid Myelitis-Keys to Diagnosis, Questions About Treatment, and Future Directions. JAMA Pediatr. 2019 Feb 1;173(2):117-118. PubMed PMID: 30500054
Messacar K, Hamilton SL, Prinzi AM, Mitchell JC, Beil ED, Dowell EB, Dominguez SR. Rapid identification of nonblood sterile site broth cultures using the FilmArray blood culture identification panel. Diagn Microbiol Infect Dis. 2019 Jan;93(1):22-23. PubMed PMID: 30213466
Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, Messer R, Maloney J, Burakoff A, Barnes M, Rogers S, Lopez AS, Routh J, Gerber I, Oberste MS, Nix WA, Abzug MJ, Tyler KL, Herlihy R, Dominguez SR. Clinical Characteristics of Enterovirus A71 Neurologic Disease During an Outbreak in Children in Colorado, 2018: An Observational Cohort Study. Accepted, In-Press 2019 The Lancet Infectious Diseases
Searns J, Cataldi JR, McCormack K, Simões E, Messacar K, Dominguez SR. A 4-Year-Old Boy With an Unusual Bacterial Meningitis Infection. J Pediatric Infect Dis Soc. 2018 Oct 9. [Epub ahead of print] PubMed PMID: 30299497
Messacar K, Hamilton SL, Prinzi AM, Mitchell JC, Beil ED, Dowell EB, Dominguez SR. Rapid identification of nonblood sterile site broth cultures using the FilmArray blood culture identification panel. Diagn Microbiol Infect Dis. 2018 Jul 31. [Epub ahead of print] PubMed PMID: 30213466
Rao S, Martin J, Ahearn MA, Osborne C, Moss A, Dempsey A, Dominguez SR, Weinberg A, Messacar KB. Neurologic Manifestations of Influenza A(H3N2) Infection in Children During the 2016-2017 Season. J Pediatric Infect Dis Soc. 2018 Dec 27. [Epub ahead of print] PubMed PMID: 30590598
Messacar K, Robinson CC, Dominguez SR. Letter to the editor: economic analysis lacks external validity to support universal syndromic testing for suspected meningitis/encephalitis. Future Microbiol. 2018 Nov;13:1553-1554. PubMed PMID: 30421966
Messacar K, Dominguez SR. Blood PCR testing for enteroviruses in young children. Lancet Infect Dis. 2018 Dec;18(12):1299-1301. PubMed PMID: 30389483
Messacar K, Burakoff A, Nix WA, Rogers S, Oberste MS, Gerber SI, Spence-Davizon E, Herlihy R, Dominguez SR. Notes from the Field: Enterovirus A71 Neurologic Disease in Children - Colorado, 2018. MMWR Morb Mortal Wkly Rep. 2018 Sep 14;67(36):1017-1018. PubMed PMID: 30212441
Messacar K. Narrow-spectrum, compared with broad-spectrum, antibiotics equally effective with less adverse events. J Pediatr. 2018 May;196:324-327. PubMed PMID: 29703366
Messacar K, Asturias EJ, Hixon AM, Van Leer-Buter C, Niesters HGM, Tyler KL, Abzug MJ, Dominguez SR. Enterovirus D68 and acute flaccid myelitis-evaluating the evidence for causality. Lancet Infect Dis. 2018 Aug;18(8):e239-e247. PubMed PMID: 29482893
Saporta-Keating SR, Simões EAF, Yu G, Federman S, Mirsky D, Dominguez SR, Chiu CY, Messacar K. A Child With Intermittent Headaches and Eosinophilic Meningitis. J Pediatric Infect Dis Soc. 2018 Dec 3;7(4):355-357. PubMed PMID: 29438532
Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ. Encephalitis in US Children. Infect Dis Clin North Am. 2018 Mar;32(1):145-162. PubMed PMID: 29224854
Messacar K, Abzug MJ, Dominguez SR. The changing epidemiology of acute flaccid paralysis warrants a paradigm shift in surveillance. J Med Virol. 2018 Jan;90(1):1-2. PubMed PMID: 29023852
Martin JA, Messacar K, Yang ML, Maloney JA, Lindwall J, Carry T, Kenyon P, Sillau SH, Oleszek J, Tyler KL, Dominguez SR, Schreiner TL. Outcomes of Colorado children with acute flaccid myelitis at 1 year. Neurology. 2017 Jul 11;89(2):129-137. PubMed PMID: 28615421
Alvarez E, Seppa M, Rivas S, Fuentes L, Valverde P, Antillón-Klussmann F, Castellanos M, Sweet-Cordero EA, Messacar K, Kurap J, Bustamante M, Howard SC, Efron B, Luna-Fineman S. Improvement in treatment abandonment in pediatric patients with cancer in Guatemala. Pediatr Blood Cancer. 2017 Oct;64(10). PubMed PMID: 28423236
Phan TG, Messacar K, Dominguez SR, da Costa AC, Deng X, Delwart E. A new densovirus in cerebrospinal fluid from a case of anti-NMDA-receptor encephalitis. Arch Virol. 2016 Nov;161(11):3231-5. PubMed PMID: 27522586
Rao S, Messacar K, Torok MR, Rick AM, Holzberg J, Montano A, Bagdure D, Curtis DJ, Oberste MS, Nix WA, de Masellis G, Robinson CC, Dominguez SR. Enterovirus D68 in Critically Ill Children: A Comparison With Pandemic H1N1 Influenza. Pediatr Crit Care Med. 2016 Nov;17(11):1023-1031. PubMed PMID: 27505715
Aliabadi N, Messacar K, Pastula DM, Robinson CC, Leshem E, Sejvar JJ, Nix WA, Oberste MS, Feikin DR, Dominguez SR. Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014. Emerg Infect Dis. 2016 Aug;22(8):1387-94. PubMed PMID: 27434186
Bagdure D, Custer JW, Rao S, Messacar K, Dominguez S, Beam BW, Bhutta A. Hospitalized Children With Encephalitis in the United States: A Pediatric Health Information System Database Study. Pediatr Neurol. 2016 Aug;61:58-62. PubMed PMID: 27353693
Maloney JA, Mirsky DM, Messacar K, Dominguez SR, Schreiner T, Stence NV. MRI findings in children with acute flaccid paralysis and cranial nerve dysfunction occurring during the 2014 enterovirus D68 outbreak. AJNR Am J Neuroradiol. 2015 Feb;36(2):245-50. PubMed PMID: 25414005
Greninger AL, Naccache SN, Messacar K, Clayton A, Yu G, Somasekar S, Federman S, Stryke D, Anderson C, Yagi S, Messenger S, Wadford D, Xia D, Watt JP, Van Haren K, Dominguez SR, Glaser C, Aldrovandi G, Chiu CY. A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study. Lancet Infect Dis. 2015 Jun;15(6):671-82. PubMed PMID: 25837569
Gaensbauer JT, Lindsey NP, Messacar K, Staples JE, Fischer M. Neuroinvasive arboviral disease in the United States: 2003 to 2012. Pediatrics. 2014 Sep;134(3):e642-50. PubMed PMID: 25113294
Maloney JA, Mirsky DM, Messacar K, Dominguez SR, Schreiner T, Stence NV. MRI Findings in Children with Acute Flaccid Paralysis and Cranial Nerve Dysfunction Occurring during the 2014 Enterovirus D68 Outbreak. AJNR Am J Neuroradiol. 2014 Nov 20. [Epub ahead of print] PubMed PMID: 25414005
Pastula DM, Aliabadi N, Haynes AK, Messacar K, Schreiner T, Maloney J, Dominguez SR, Davizon ES, Leshem E, Fischer M, Nix WA, Oberste MS, Seward J, Feikin D, Miller L, Centers for Disease Control and Prevention (CDC). Acute neurologic illness of unknown etiology in children - Colorado, August-September 2014. MMWR Morb Mortal Wkly Rep. 2014 Oct 10;63(40):901-2. PubMed PMID: 25299607