Toshi Clark, MD

Professional Titles

• Assistant Professor

Recognitions

• Co-Chief Resident, Nassau University Medical Center (2011)
  
• Trainee Research Award, Radiological Society of North America (2010)
  

Publications

• Pozdeyev N, Dighe M, Barrio M, Raeburn C, Smith H, Fisher M, Chavan S, Rafaels N, Shortt JA, Lin M, Leu MG, Clark T, Marshall C, Haugen BR, Subramanian D, Crooks K, Gignoux C, Cohen T. Thyroid Cancer Polygenic Risk Score Improves Classification of Thyroid Nodules as Benign or Malignant. J Clin Endocrinol Metab. 2024 Jan 18;109(2):402-412. PubMed PMID: 37683082
• Norris EC, Schneider G, Clark TJ, Kirchin MA, Wilson GJ, Maki JH. Efficacy of Whole-Blood Model of Gadolinium-Based Contrast Agent Relaxivity in Predicting Vascular MR Signal Intensity In Vivo. J Magn Reson Imaging. 2024 Aug;60(2):615-627. PubMed PMID: 37916957
• Yee EJ, Torphy RJ, Myers EK, Meguid C, Franklin O, Sugawara T, Franco SR, Clark TJ, Mungo B, Ahrendt SA, Schulick RD, Del Chiaro M, McCarter MM. Dynamic Anthropometrics in Pancreatic Cancer: Associations Between Body Composition Changes During Neoadjuvant Therapy and Survival Outcomes After Resection. Ann Surg Oncol. 2024 Nov;31(12):8340-8351. PubMed PMID: 39120842
• Pozdeyev N, Dighe M, Barrio M, Raeburn C, Smith H, Fisher M, Chavan S, Rafaels N, Shortt JA, Lin M, Leu MG, Clark T, Marshall C, Haugen BR, Subramanian D, Crooks K, Gignoux C, Cohen T. Thyroid Cancer Polygenic Risk Score Improves Classification of Thyroid Nodules as Benign or Malignant. J Clin Endocrinol Metab. 2024 Jan 18;109(2):402-412. PubMed PMID: 37683082
• Norris EC, Schneider G, Clark TJ, Kirchin MA, Wilson GJ, Maki JH. Efficacy of Whole-Blood Model of Gadolinium-Based Contrast Agent Relaxivity in Predicting Vascular MR Signal Intensity In Vivo. J Magn Reson Imaging. 2023 Nov 2. [Epub ahead of print] PubMed PMID: 37916957
• Badgery HE, Muhlen-Schulte T, Zalcberg JR, D'souza B, Gerstenmaier JF, Pickett C, Samra J, Croagh D. Determination of "borderline resectable" pancreatic cancer - A global assessment of 30 shades of grey. HPB (Oxford). 2023 Nov;25(11):1393-1401. PubMed PMID: 37558564
• Clark TJ, Wilson GJ, Maki JH. Relationship Between Simulated Gadolinium-Based Contrast Agent Injection Profile and Achievable Resolution Metrics in Contrast-Enhanced Magnetic Resonance Angiography. J Magn Reson Imaging. 2021 Oct 25. [Epub ahead of print] PubMed PMID: 34694039
• Wu ZJ, Clark TJ, Hippe DS, Soloff EV, Zhang M, Hsu L, Wang CL. Comparison of Histogram-Based Gaussian Analysis With and Without Noise Correction for the Characterization of Indeterminate Adrenal Nodules. AJR Am J Roentgenol. 2020 Oct;215(4):896-902. PubMed PMID: 32809863
• Lang J, Capasso A, Jordan KR, French JD, Kar A, Bagby SM, Barbee J, Yacob BW, Head LS, Tompkins KD, Freed BM, Somerset H, Clark TJ, Pitts TM, Messersmith WA, Eckhardt SG, Wierman ME, Leong S, Kiseljak-Vassiliades K. Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment. J Clin Endocrinol Metab. 2020 Jan 1;105(1). PubMed PMID: 31513709
• Lang J, Capasso A, Jordan KR, French JD, Kar A, Bagby SM, Barbee J, Yacob BW, Head LS, Tompkins KD, Freed BM, Somerset H, Clark TJ, Pitts TM, Messersmith WA, Eckhardt SG, Wierman ME, Leong S, Kiseljak-Vassiliades K. Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment. J Clin Endocrinol Metab. 2020 Jan 1;105(1). PubMed PMID: 31513709
• Head L, Kiseljak-Vassiliades K, Clark TJ, Somerset H, King J, Raeburn C, Albuja-Cruz M, Weyant M, Cleveland J, Wierman ME, Leong S. Response to Immunotherapy in Combination With Mitotane in Patients With Metastatic Adrenocortical Cancer. J Endocr Soc. 2019 Dec 1;3(12):2295-2304. PubMed PMID: 31745526
• Erkan B, Meier J, Clark TJ, Kaplan J, Lambert JR, Chang S. Non-invasive diagnostic criteria of hepatocellular carcinoma: Comparison of diagnostic accuracy of updated LI-RADS with clinical practice guidelines of OPTN-UNOS, AASLD, NCCN, EASL-EORTC, and KLSCG-NCC. PLoS One. 2019;14(12):e0226291. PubMed PMID: 31821360
• Clark TJ, McKinney K, Jensen A, Patel NU. Risk Threshold Algorithm for Thyroid Nodule Management Demonstrates Increased Specificity and Diagnostic Accuracy as Compared With American College of Radiology Thyroid Imaging, Reporting and Data System; Society of Radiologists in Ultrasound; and American Thyroid Association Management Guidelines. Ultrasound Q. 2019 Sep;35(3):224-227. PubMed PMID: 30724871
• Lewis C, Restauri N, Clark T. Strategies for Increasing Radiologist Efficiency. Curr Probl Diagn Radiol. 2019 Mar - Apr;48(2):103-104. PubMed PMID: 30583911
• Restauri N, Nyberg E, Clark T. Cultivating Meaningful Work in Healthcare: A Paradigm and Practice. Curr Probl Diagn Radiol. 2019 May - Jun;48(3):193-195. PubMed PMID: 30638757
• Maki JH, Wilson GJ, Clark TJ. Evaluation of four injection profiles for uniform contrast-enhanced signal intensity profiles in MR angiography. J Magn Reson Imaging. 2019 Dec;50(6):1808-1816. PubMed PMID: 31095810
• Clark T, Nyberg E. Creating the Black Box: A Primer on Convolutional Neural Network Use in Image Interpretation. Curr Probl Diagn Radiol. 2019 Jul 9. [Epub ahead of print] PubMed PMID: 31326143
• Boehnke M, Pokharel S, Nyberg E, Clark T. Financial Education for Radiology Residents: Significant Improvement in Measured Financial Literacy After a Targeted Intervention. J Am Coll Radiol. 2018 Jan;15(1 Pt A):97-99.e1. PubMed PMID: 28807387
• Lakhani P, Prater AB, Hutson RK, Andriole KP, Dreyer KJ, Morey J, Prevedello LM, Clark TJ, Geis JR, Itri JN, Hawkins CM. Machine Learning in Radiology: Applications Beyond Image Interpretation. J Am Coll Radiol. 2018 Feb;15(2):350-359. PubMed PMID: 29158061
• Patel NU, Lind KE, McKinney K, Clark TJ, Pokharel SS, Meier JM, Stamm ER, Garg K, Haugen B. Clinical Validation of a Predictive Model for the Presence of Cervical Lymph Node Metastasis in Papillary Thyroid Cancer. AJNR Am J Neuroradiol. 2018 Apr;39(4):756-761. PubMed PMID: 29449283
• Brimhall B, Han S, Tatman PD, Clark TJ, Wani S, Brauer B, Edmundowicz S, Wagh MS, Attwell A, Hammad H, Shah RJ. Increased Incidence of Pseudoaneurysm Bleeding With Lumen-Apposing Metal Stents Compared to Double-Pigtail Plastic Stents in Patients With Peripancreatic Fluid Collections. Clin Gastroenterol Hepatol. 2018 Sep;16(9):1521-1528. PubMed PMID: 29474970
• Boehnke M, Patel N, McKinney K, Clark T. Diagnostic Performance of SRU and ATA Thyroid Nodule Classification Algorithms as Tested With a 1 Million Virtual Thyroid Nodule Model. Curr Probl Diagn Radiol. 2018 Jan - Feb;47(1):10-13. PubMed PMID: 28554789
• Flood TF, Pokharel SS, Patel NU, Clark TJ. Accuracy and Interobserver Variability in Reporting of PI-RADS Version 2. J Am Coll Radiol. 2017 Sep;14(9):1202-1205. PubMed PMID: 28571670
• Clark T, Corral J, Nyberg E, Bang T, Trivedi P, Sachs P, Mcarthur T, Flug J, Rumack C. Launchpad for Onboarding New Faculty Into Academic Life. Curr Probl Diagn Radiol. 2017 Apr 27. [Epub ahead of print] PubMed PMID: 28606379
• Lakhani P, Prater AB, Hutson RK, Andriole KP, Dreyer KJ, Morey J, Prevedello LM, Clark TJ, Geis JR, Itri JN, Hawkins CM. Machine Learning in Radiology: Applications Beyond Image Interpretation. J Am Coll Radiol. 2017 Nov 16. [Epub ahead of print] PubMed PMID: 29158061
• Clark TJ, Gunn ML. CT Angiography in the Emergency Department: Maximizing Contrast Enhancement and Image Quality While Minimizing Radiation Dose and Contrast Material Volume: Vascular/Interventional Radiology. Radiographics. 2017 Jul-Aug;37(4):1304-1305. PubMed PMID: 28696854
• Clark TJ, Mieloszyk RJ, Bhargava P. What Do George Clooney and Sarah Jessica Parker Have in Common? Big Data. Curr Probl Diagn Radiol. 2017 May - Jun;46(3):171-172. PubMed PMID: 28434559
• Clark TJ, Wilson GJ, Maki JH. Effect of injection rate on contrast-enhanced MR angiography image quality: Modulation transfer function analysis. Magn Reson Med. 2017 Jul;78(1):357-369. PubMed PMID: 27478136
• Hsu LD, Wang CL, Clark TJ. Characterization of Adrenal Adenoma by Gaussian Model-Based Algorithm. Curr Probl Diagn Radiol. 2016 Sep-Oct;45(5):312-8. PubMed PMID: 27020253
• Stamm ER, Meier JM, Pokharel SS, Clark T, Glueck DH, Lind KE, Roberts KM. Normal main portal vein diameter measured on CT is larger than the widely referenced upper limit of 13 mm. Abdom Radiol (NY). 2016 Oct;41(10):1931-6. PubMed PMID: 27251734
• Clark TJ, Coats G. Adherence to ACR Incidental Finding Guidelines. J Am Coll Radiol. 2016 Dec;13(12 Pt A):1530-1533. PubMed PMID: 27319370
• Nielsen JP, Clark TJ. Radiologist-Centered Decision Support Applications. J Am Coll Radiol. 2016 Sep;13(9):1083-7. PubMed PMID: 27497521
• Clark TJ, Wilson GJ, Maki JH. Effect of injection rate on contrast-enhanced MR angiography image quality: Modulation transfer function analysis. Magn Reson Med. 2016 Aug 1. [Epub ahead of print] PubMed PMID: 27478136
• Clark TJ, Flood TF, Maximin ST, Sachs PB. Lung CT Screening Reporting and Data System Speed and Accuracy Are Increased With the Use of a Semiautomated Computer Application. J Am Coll Radiol. 2015 Oct 22. [Epub ahead of print] PubMed PMID: 26507823
• Clark TJ, Pokharel S, Meier J, Wang C, Maximin S. Thyroid Nodule Doubling Time is Not a Reliable Indicator of Benign or Malignant Nature. Ultrasound Q. 2015 Oct 5. [Epub ahead of print] PubMed PMID: 26441381
• Clark T, Maximin S, Meier J, Pokharel S, Bhargava P. Hepatocellular Carcinoma: Review of Epidemiology, Screening, Imaging Diagnosis, Response Assessment, and Treatment. Curr Probl Diagn Radiol. 2015 Nov-Dec;44(6):479-86. PubMed PMID: 25979220
• Lai J, Clark TJ, Tan JH, Delaney S, Jolley JA. Ultrasound findings in fetal congenital heart block associated with maternal anti-Ro/SSA and Anti-La/SSB antibodies. Ultrasound Q. 2015 Mar;31(1):34-6. PubMed PMID: 25706362
• Clark TJ, Suby-Long T. Computed tomography obtained during acute heart failure: a literature review and presentation of a novel case demonstrating venointerstitial renal, hepatic parenchymal, renal vein, and inferior vena cava contrast reflux, pooling, and layering. Radiology Case Reports 2015; in press.
• Clark TJ, McNeeley MF, Maki JH. Design and implementation of handheld and desktop software for the structured reporting of hepatic masses using the LI-RADS schema. Acad Radiol. 2014 Apr;21(4):491-506. PubMed PMID: 24594419
• Lai J, Clark TJ, Tan JH, Delaney S, Jolley JA. Ultrasound Findings in Fetal Congenital Heart Block Associated with Maternal antiRo/SSA and antiLa/SSB Antibodies. Ultrasound Quarterly 2014; in press.
• Clark TJ, Maximin S, Shriki J, Bhargava P. Tumoral pulmonary emboli from angioinvasive hepatocellular carcinoma. Current Problems in Diagnostic Radiology 2014; in press.
• Clark TJ, McKinney K, Jensen A, Patel NU. Risk Threshold Algorithm for thyroid nodule management demonstrates increased specificity and diagnostic accuracy as compared to ACR TI-RADS, SRU, and ATA management guidelines. Ultrasound Quarterly, accepted for publication Nov 6, 2018.
• Lewis C, Restauri N, Clark TJ. Strategies for Increasing Radiologist Efficiency. Current Problems in Diagnostic Radiology, accepted for publication Dec 5, 2018.
• Restauri N, Nyberg E, Clark TJ. Cultivating Meaningful Work in Healthcare: A Paradigm and Practice. Current Problems in Diagnostic Radiology, accepted for publication Dec 5, 2018.
• Clark TJ, Hsu LD, Hippe D, Cowan S, Carnell J, Wang CL. Evaluation of Diagnostic Accuracy: Multidetector CT Image Noise Correction Improves Specificity of a Gaussian Model-based Algorithm used for Characterization of Incidental Adrenal Nodules. Abdominal Radiology, accepted for publication December 11, 2018.

Practice Locations

• University of Colorado Hospital

Specialty Information

• Abdominal Radiology, Board Certification (2013)

• Radiology - Abdominal Imaging
• Radiology - CT Scans
• Radiology - Magnetic Resonance Imaging (MRI)
• Radiology - X-Rays
• Radiology