David Mathes, MD

Professor, Surgery-Plastic/Reconstructive

FacultyPhoto
Medical School
  • MD, Tulane University School of Medicine (1996)
Internship
  • New York Presbyterian Hospital Program (1998)
Residencies
  • New York Presbyterian Hospital Program, Surgery (2003)
  • New York Presbyterian Hospital Program, Chief Resident, Surgery (2004)
  • Children's Medical Center of Dallas/University of Texas Southwestern Medical School Program, Plastic Surgery (2006)
Fellowships
  • Massachusetts General Hospital/Brigham and Women's Hospital/Harvard Medical School Program, Surgery (2001)
Languages
English
Department
Surgery-Plastic/Reconstructive

Professional Titles

  • Division Chief, Plastic and Reconstructive Surgery
  • Director, Plastic & Reconstructive Surgery Clinic

Publications

  • Combs PD, Sousa JD, Louie O, Said HK, Neligan PC, Mathes DW. Comparison of vertical and oblique rectus abdominis myocutaneous flaps for pelvic, perineal, and groin reconstruction. Plast Reconstr Surg. 2014 Aug;134(2):315-23. PubMed PMID: 25068330
  • Sandvall BK, Suver DW, Said HK, Mathes DW, Neligan PC, Dellinger EP, Louie O. Comparison of Synthetic and Biologic Mesh in Ventral Hernia Repair Using Components Separation Technique. Ann Plast Surg. 2014 Jul 4. [Epub ahead of print] PubMed PMID: 25003419
  • Mathes DW, Solari MG, Gazelle GS, Butler PE, Wu A, Nazzal A, Nielsen GP, Huang CA, Sachs DH, Lee WP, Randolph MA. Stable mixed hematopoietic chimerism permits tolerance of vascularized composite allografts across a full major histocompatibility mismatch in swine. Transpl Int. 2014 Oct;27(10):1086-96. PubMed PMID: 24963743
  • Mathes DW, Chang J, Hwang B, Graves SS, Storer BE, Butts-Miwongtum T, Sale GE, Storb R. Simultaneous transplantation of hematopoietic stem cells and a vascularized composite allograft leads to tolerance. Transplantation. 2014 Jul 27;98(2):131-8. PubMed PMID: 24918616
  • Mathes DW, Edwards JA, Anzai Y, Neligan PC. A functional periorbital subunit allograft: vascular, anatomic, and technical considerations for future subunit facial transplantation. J Plast Reconstr Aesthet Surg. 2014 Oct;67(10):1371-7. PubMed PMID: 24917373
  • Um GT, Chang J, Louie O, Colohan SM, Said HK, Neligan PC, Mathes DW. Implantable Cook-Swartz Doppler probe versus Synovis Flow Coupler for the post-operative monitoring of free flap breast reconstruction. J Plast Reconstr Aesthet Surg. 2014 Jul;67(7):960-6. PubMed PMID: 24767693
  • Liu DZ, Mathes DW, Neligan PC, Said HK, Louie O. Comparison of outcomes using AlloDerm versus FlexHD for implant-based breast reconstruction. Ann Plast Surg. 2014 May;72(5):503-7. PubMed PMID: 23636114
  • Chang J, Graves SS, Butts-Miwongtum T, Sale GE, Storb R, Mathes DW. Long-term Tolerance Toward Haploidentical Vascularized Composite Allograft Transplantation in a Canine Model Using Bone Marrow or Mobilized Stem Cells. Transplantation. 2016 Dec;100(12):e120-e127. PubMed PMID: 27861292
  • Miranda SG, Liu Y, Morrison SD, Sood RF, Gallagher T, Gougoutas AJ, Colohan SM, Louie O, Mathes DW, Neligan PC, Said HK. Improved healthcare economic outcomes after liposomal bupivacaine administration in first-stage breast reconstruction. J Plast Reconstr Aesthet Surg. 2016 Oct;69(10):1456-7. PubMed PMID: 27475335
  • Sandvall BK, Suver DW, Said HK, Mathes DW, Neligan PC, Dellinger EP, Louie O. Comparison of Synthetic and Biologic Mesh in Ventral Hernia Repair Using Components Separation Technique. Ann Plast Surg. 2016 Jun;76(6):674-9. PubMed PMID: 25003419
  • Heelan Gladden AA, Sams S, Gleisner A, Finlayson C, Kounalakis N, Hosokawa P, Brown R, Chong T, Mathes D, Murphy C. Discussion of: "Re-excision rates after breast conserving surgery following the 2014 SSO-ASTRO guidelines". Am J Surg. 2017 Dec;214(6):1110-1111. PubMed PMID: 29033142
  • LaRanger R, Karimpour-Fard A, Costa C, Mathes D, Wright WE, Chong T. Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. Plast Reconstr Surg. 2018 Nov 26. [Epub ahead of print] PubMed PMID: 30531622
  • Smith JM, Broyles JM, Guo Y, Tuffaha SH, Mathes D, Sacks JM. Human acellular dermis increases surgical site infection and overall complication profile when compared with submuscular breast reconstruction: An updated meta-analysis incorporating new products(?). J Plast Reconstr Aesthet Surg. 2018 Nov;71(11):1547-1556. PubMed PMID: 30093286
  • Sousa J, Sood R, Liu D, Calhoun K, Louie O, Neligan P, Said H, Mathes D. Comparison of Outcomes in Immediate Implant-Based Breast Reconstruction Versus Mastectomy Alone. Plast Surg (Oakv). 2018 Feb;26(1):18-25. PubMed PMID: 29619355
  • Gougoutas AJ, Said HK, Um G, Chapin A, Mathes DW. Nipple-Areola Complex Reconstruction. Plast Reconstr Surg. 2018 Mar;141(3):404e-416e. PubMed PMID: 29481412
  • Colakoglu S, Tebockhorst S, Chong TW, Mathes DW. Patient Safety in Microvascular Plastic Surgery. J Reconstr Microsurg. 2019 Nov;35(9):631-639. PubMed PMID: 31327160
  • Shah NR, Cohen WA, Ayyala HS, Sorkin J, Mathes D, Ignatiuk A. Bilateral Cross Arm Flaps for Resurfacing Hands After High-Voltage Injury. Eplasty. 2019;19:ic2. PubMed PMID: 30680049
  • LaRanger R, Karimpour-Fard A, Costa C, Mathes D, Wright WE, Chong T. Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. Plast Reconstr Surg. 2019 Feb;143(2):490-494. PubMed PMID: 30531622
  • Johnson AC, Colakoglu S, Chong TW, Mathes DW. Indocyanine Green Angiography in Breast Reconstruction: Utility, Limitations, and Search for Standardization. Plast Reconstr Surg Glob Open. 2020 Mar;8(3):e2694. PubMed PMID: 32537350
  • Colakoglu S, Johnson A, Anderson J, Mathes DW, Chong TW. Changes to Venous Flow Coupler Signal during DIEP Flap Inset Can Be Predictive of Poor Clinical Outcomes in Autologous Breast Reconstruction. J Reconstr Microsurg. 2020 Jul;36(6):466-470. PubMed PMID: 32172526
  • Wang H, Wang Z, Zhang H, Qi Z, Johnson AC, Mathes D, Pomfret EA, Rubin E, Huang CA, Wang Z. Bispecific human IL2-CCR4 immunotoxin targets human cutaneous T-cell lymphoma. Mol Oncol. 2020 May;14(5):991-1000. PubMed PMID: 32107846
  • Colakoglu S, Tebockhorst S, Mathes DW. Is Vascularized Composite Allograft Transplantation Experimental or an Accepted Surgical Procedure: Results from a National Survey. J Reconstr Microsurg. 2020 May;36(4):276-280. PubMed PMID: 31986534
  • Yang JH, Johnson AC, Colakoglu S, Huang CA, Mathes DW. Clinical and preclinical tolerance protocols for vascularized composite allograft transplantation. Arch Plast Surg. 2021 Nov;48(6):703-713. PubMed PMID: 34818720
  • Johnson AC, King BBT, Colakoglu S, Yang JH, Chong TW, Mathes DW. The Influence of Closing the Abdominal Donor-Site Superficial Fascial System in Deep Inferior Epigastric Perforator Flap Breast Reconstruction. Plast Reconstr Surg. 2021 Sep 1;148(3):357e-364e. PubMed PMID: 34432680
  • Colakoglu S, Tebockhorst S, Freedman J, Douglass S, Siddikoglu D, Chong TW, Mathes DW. CT angiography prior to DIEP flap breast reconstruction: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):45-51. PubMed PMID: 34332925
  • Anderson JB, Foglio A, Harrant AB, Huang CA, Hultman CS, Mathes DW, Chong TW. Scoping Review of Therapeutic Strategies for Keloids and Hypertrophic Scars. Plast Reconstr Surg Glob Open. 2021 Mar;9(3):e3469. PubMed PMID: 33786262
  • Colakoglu S, Johnson A, Mureau MAM, Douglass S, Kaoutzanis C, Chong TW, Mathes DW, Cohen JB. Telehealth: Could It Be an Avenue to Microvascular Breast Reconstruction for Patients with Geographical Barriers?. J Reconstr Microsurg. 2021 Sep;37(7):597-601. PubMed PMID: 33592632
  • Qi Z, Qiu Y, Wang Z, Zhang H, Lu L, Liu Y, Mathes D, Pomfret EA, Gao D, Lu SL, Wang Z. A novel diphtheria toxin-based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma. Mol Oncol. 2021 Apr;15(4):1054-1068. PubMed PMID: 33540470
  • Christodoulou N, Wolfe B, Mathes DW, Malgor RD, Kaoutzanis C. Vacuum-assisted closure therapy for the management of deep sternal wound complications: A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2023 Oct 17. [Epub ahead of print] PubMed PMID: 37951723
  • Qiu Y, Qi Z, Wang Z, Cao Y, Lu L, Zhang H, Mathes D, Pomfret EA, Lu SL, Wang Z. EGF-IL2 bispecific and bivalent EGF fusion toxin efficacy against syngeneic head and neck cancer mouse models. Oncol Rep. 2023 Feb;49(2). PubMed PMID: 36579667
  • Schols RM, Dip F, Lo Menzo E, Haddock NT, Landin L, Lee BT, Malagón P, Masia J, Mathes DW, Nahabedian MY, Neligan PC, Newman MI, Phillips BT, Pons G, Pruimboom T, Qiu SS, Ritschl LM, Rozen WM, Saint-Cyr M, Song SY, van der Hulst RRWJ, Venturi ML, Wongkietkachorn A, Yamamoto T, White KP, Rosenthal RJ. Delphi survey of intercontinental experts to identify areas of consensus on the use of indocyanine green angiography for tissue perfusion assessment during plastic and reconstructive surgery. Surgery. 2022 Dec;172(6S):S46-S53. PubMed PMID: 36427930
  • Lee AD, Hale EW, Mundra L, Le E, Kaoutzanis C, Mathes DW. The heart of it all: Body dysmorphic disorder in cosmetic surgery. J Plast Reconstr Aesthet Surg. 2023 Dec;87:442-448. PubMed PMID: 37944455
  • Tuano KR, Yang JH, Kleck CJ, Mathes DW, Chong TW. Multidisciplinary Treatment of Persistent Nontuberculous Mycobacterial Spinal Hardware Infection with a Pedicled Superior Gluteal Artery Perforator Flap. Arch Plast Surg. 2022 Sep;49(5):604-607. PubMed PMID: 36159388
  • Yang JH, Huynh V, Leonard LD, Kovar A, Bronsert M, Ludwigson A, Wolverton D, Hampanda K, Christian N, Kim SP, Ahrendt G, Mathes DW, Tevis SE. Are Diagnostic Delays Associated with Distress in Breast Cancer Patients?. Breast Care (Basel). 2023 Aug;18(4):240-248. PubMed PMID: 37900555
  • Garoosi K, Mundra L, Jabbari K, Winocour J, Iorio ML, Mathes DW, Kaoutzanis C. Comorbid Conditions and Complications in Body Contouring Surgery: A Retrospective Review. Aesthet Surg J Open Forum. 2023;5:ojad080. PubMed PMID: 37711766
  • Garoosi K, Lee N, Tuano KR, Lee ELH, Cohen J, Winocour J, Mathes DW, Iorio ML, Kaoutzanis C. Analysis of Complications in Patients With a History of Cannabis Use and Tobacco Use Undergoing Implant-Based Breast Reconstruction. Aesthet Surg J. 2023 Dec 14;44(1):NP41-NP48. PubMed PMID: 37706275
  • Rhee DH, Constantine RS, Colakoglu S, Karimpour-Fard A, Kaoutzanis C, Mathes DW, Chong TW. Clinical outcomes of intraoperative dopamine infusion for hypotensive patients during breast reconstruction with deep inferior epigastric perforator (DIEP) flaps. J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):2982-2990. PubMed PMID: 35915016
  • Jacobson NM, Carerra E, Treat A, McDonnell M, Mathes D, Kaoutzanis C. Hybrid modeling techniques for 3D printed deep inferior epigastric perforator flap models. 3D Print Med. 2023 Sep 12;9(1):26. PubMed PMID: 37700101
  • Colakoglu S, Yang J, French MM, Winocour J, Um GT, Blumenauer B, Siddikoglu D, Mureau MAM, Chong T, Higdon K, Perdikis G, Inchauste SM, Kaoutzanis C, Mathes DW. Importance of Incidental Findings in Preoperative Computed Tomography Angiography for Abdominally Based Free Flap Breast Reconstruction: A Multi-Institutional Study. Plast Reconstr Surg. 2022 Sep 1;150(3):527-535. PubMed PMID: 35748758
  • Tuaño KR, Yang JH, Fisher MH, Le E, Khatter NJ, Kalia N, Colakoglu S, Cohen JB, Kaoutzanis C, Chong TW, Mathes DW. Venous Thromboembolism after Deep Inferior Epigastric Perforator Flap Breast Reconstruction: Review of Outcomes After a Postoperative Prophylaxis Protocol. Plast Reconstr Surg. 2023 Jul 25. [Epub ahead of print] PubMed PMID: 37506353
  • Aravind P, Colakoglu S, Bhoopalam M, Ibrahim A, Mathes D, Kaoutzanis C, Mureau M, Reddy S. Perforator Characteristics and Impact on Postoperative Outcomes in DIEP Flap Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2023 Feb;39(2):138-147. PubMed PMID: 35714621
  • Yoon Y, Lee N, Lee AD, Gehring MB, Constantine R, Mathes DW, Yu JW, Khechoyan D, Iorio ML, Kaoutzanis C. Analysis of postoperative complications related to cannabis and tobacco usage in patients undergoing mandible facial fracture surgeries. J Plast Reconstr Aesthet Surg. 2023 Oct;85:127-133. PubMed PMID: 37482026
  • McCranie A, Desjardins H, Mathes D, Kaoutzanis C. Should Physical Therapy Be an Insurance Requirement for Patients Seeking a Breast Reduction?. Aesthet Surg J. 2023 Aug 17;43(9):NP713-NP714. PubMed PMID: 37185654
  • Johnson AC, Colakoglu S, Siddikoglu D, Li A, Kaoutzanis C, Cohen JB, Chong TW, Mathes DW. Impact of Dermal Matrix Brand in Implant-Based Breast Reconstruction Outcomes. Plast Reconstr Surg. 2022 Jul 1;150(1):17-25. PubMed PMID: 35499525
  • Mundra L, Garossi K, Iorio M, Mathes D, Winocour J, Kaoutzanis C. Opioid-Prescribing Patterns in Body Contouring Surgery. Aesthet Surg J. 2023 Aug 17;43(9):978-985. PubMed PMID: 37185594
  • Wang Z, Ma J, Zhang H, Ramakrishna R, Mintzlaff D, Mathes DW, Pomfret EA, Lucia MS, Gao D, Haverkos BM, Wang Z. CCR4-IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T-cell lymphoma in a mouse CTCL model. FEBS Open Bio. 2023 Jul;13(7):1309-1319. PubMed PMID: 37157185
  • Jabbari K, Gehring MB, Iorio ML, Mathes DW, Kaoutzanis C. Macromastia and Reduction Mammaplasty: Analysis of Outpatient Cost of Care and Opioid Consumption at 5 Years Postoperatively. Aesthet Surg J. 2023 Sep 14;43(10):NP763-NP770. PubMed PMID: 37071801
  • Khavanin N, Yang JH, Colakoglu S, Tuano KR, Wong JO, Cohen JB, Chong TW, Reddy S, Mathes DW, Kaoutzanis C. Breast Reconstruction Trends in the Setting of Postmastectomy Radiation Therapy: Analysis of Practices among Plastic Surgeons in the United States. Plast Reconstr Surg Glob Open. 2023 Feb;11(2):e4800. PubMed PMID: 36817273
  • Yang JH, Colakoglu S, Mureau MAM, Siddikoglu D, Johnson AC, Cohen JB, Lee BT, Chong TW, Mathes DW, Kaoutzanis C. Midline epigastric scars can be associated with higher umbilical complications following DIEP flap harvest. J Plast Reconstr Aesthet Surg. 2022 Jun;75(6):1826-1832. PubMed PMID: 35172949
  • Colakoglu S, Tebockhorst S, Freedman J, Douglass S, Siddikoglu D, Chong TW, Mathes DW. CT angiography prior to DIEP flap breast reconstruction: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):45-51. PubMed PMID: 34332925
  • Le ELH, Saifee J, Constantine R, Tuaño K, Yang J, Kaoutzanis C, Mathes DW, Iorio ML. Extended Venous Thromboembolism Chemoprophylaxis following Microsurgical Breast Reconstruction: Analysis of Trends in Postoperative Anticoagulation. Plast Reconstr Surg. 2023 Jul 1;152(1):20-27. PubMed PMID: 36728476
  • Qiu Y, Qi Z, Wang Z, Cao Y, Lu L, Zhang H, Mathes D, Pomfret EA, Lu SL, Wang Z. EGF-IL2 bispecific and bivalent EGF fusion toxin efficacy against syngeneic head and neck cancer mouse models. Oncol Rep. 2023 Feb;49(2). PubMed PMID: 36579667
  • Schols RM, Dip F, Lo Menzo E, Haddock NT, Landin L, Lee BT, Malagón P, Masia J, Mathes DW, Nahabedian MY, Neligan PC, Newman MI, Phillips BT, Pons G, Pruimboom T, Qiu SS, Ritschl LM, Rozen WM, Saint-Cyr M, Song SY, van der Hulst RRWJ, Venturi ML, Wongkietkachorn A, Yamamoto T, White KP, Rosenthal RJ. Delphi survey of intercontinental experts to identify areas of consensus on the use of indocyanine green angiography for tissue perfusion assessment during plastic and reconstructive surgery. Surgery. 2022 Dec;172(6S):S46-S53. PubMed PMID: 36427930
  • Tuano KR, Yang JH, Kleck CJ, Mathes DW, Chong TW. Multidisciplinary Treatment of Persistent Nontuberculous Mycobacterial Spinal Hardware Infection with a Pedicled Superior Gluteal Artery Perforator Flap. Arch Plast Surg. 2022 Sep;49(5):604-607. PubMed PMID: 36159388
  • Rhee DH, Constantine RS, Colakoglu S, Karimpour-Fard A, Kaoutzanis C, Mathes DW, Chong TW. Clinical outcomes of intraoperative dopamine infusion for hypotensive patients during breast reconstruction with deep inferior epigastric perforator (DIEP) flaps. J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):2982-2990. PubMed PMID: 35915016
  • Colakoglu S, Yang J, French MM, Winocour J, Um GT, Blumenauer B, Siddikoglu D, Mureau MAM, Chong T, Higdon K, Perdikis G, Inchauste SM, Kaoutzanis C, Mathes DW. Importance of Incidental Findings in Preoperative Computed Tomography Angiography for Abdominally Based Free Flap Breast Reconstruction: A Multi-Institutional Study. Plast Reconstr Surg. 2022 Sep 1;150(3):527-535. PubMed PMID: 35748758
  • Aravind P, Colakoglu S, Bhoopalam M, Ibrahim A, Mathes D, Kaoutzanis C, Mureau M, Reddy S. Perforator Characteristics and Impact on Postoperative Outcomes in DIEP Flap Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2023 Feb;39(2):138-147. PubMed PMID: 35714621
  • Johnson AC, Colakoglu S, Siddikoglu D, Li A, Kaoutzanis C, Cohen JB, Chong TW, Mathes DW. Impact of Dermal Matrix Brand in Implant-Based Breast Reconstruction Outcomes. Plast Reconstr Surg. 2022 Jul 1;150(1):17-25. PubMed PMID: 35499525
  • Yang JH, Colakoglu S, Mureau MAM, Siddikoglu D, Johnson AC, Cohen JB, Lee BT, Chong TW, Mathes DW, Kaoutzanis C. Midline epigastric scars can be associated with higher umbilical complications following DIEP flap harvest. J Plast Reconstr Aesthet Surg. 2022 Jun;75(6):1826-1832. PubMed PMID: 35172949
  • Colakoglu S, Tebockhorst S, Freedman J, Douglass S, Siddikoglu D, Chong TW, Mathes DW. CT angiography prior to DIEP flap breast reconstruction: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):45-51. PubMed PMID: 34332925

Practice Locations

UCHealth Plastic and Reconstructive Surgery Clinic - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-0800

CU Medicine Plastic and Reconstructive Surgery - Highlands Ranch Specialty Care Center
1500 Park Central Drive
Suite 201
Highlands Ranch, CO 80129
720-516-4085

CU Medicine Cosmetic Surgery
12348 E. Montview Blvd
CU Anschutz Health and Wellness Center, 2nd floor
Aurora, CO 80045
303-724-8700

Rocky Mountain Regional Veterans Administration Medical Center
1700 Wheeling St
Aurora, CO 80045
303-399-8020

Hospital Affiliation
  • University of Colorado Hospital
  • UCHealth Highlands Ranch Hospital
  • Veterans Affairs Medical Center

Center Affiliations

Specialty Information

Specialties
  • Surgery, Board Certification (2005)
  • Plastic Surgery, Board Certification (2007)
Conditions & Treatments
  • Surgery
  • Surgery - Breast Surgery
  • Surgery - Free flaps and limb salvage
  • Surgery - Bariatric Surgery - Weight Loss
  • Surgery - Plastic, Reconstructive and Aesthetic Surgery
  • Surgery - Gender Affirmation Surgery
  • Cancers - Breast Cancer
  • Cancers

School of Medicine

CU Anschutz
Fitzsimons Building

13001 East 17th Place

Aurora, CO 80045

303.724.5375

School
General
Students