David Mathes, MD

Professional Titles

• Division Chief, Plastic and Reconstructive Surgery
• Director, Plastic & Reconstructive Surgery Clinic

Recognitions

• 5280 Top Doc - Plastic Surgery, 5280 Magazine (2025)
• 3 Best Plastic Surgeons in Aurora, CO, ThreeBestRated.com (2025)
• 3 Best Plastic Surgeons in Aurora, CO, ThreeBestRated.com (2024)
• Caste Connolly Top Doctors - Plastic Surgery, Castle Connolly (2024)

Publications

• Green EA, Shade KN, Gomez DA, Khechoyan AD, Yu JW, Irwin TJ, French B, Nguyen PD, Mathes DW, Khechoyan DY. Current Landscape of Medicolegal Reform in the United States: A Plastic Surgery Perspective. Ann Plast Surg. 2026 Jan 1;96(1):101-111. PubMed PMID: 41417711
• Haas EJ, Thurimella K, Baghshomali Y, Egan K, Kaoutzanis C, Irwin T, McCarter M, David EA, Mathes DW, Yu JW. Supercharged Pedicled Jejunal Interposition for Esophageal Reconstruction: A Systematic Review and Meta-analysis of Adult and Pediatric Patients. J Reconstr Microsurg. 2026 Jan 14. [Epub ahead of print] PubMed PMID: 41534855
• Le DM, Hoffman GR, Le T, Elkhill C, Porras A, French B, Yu JW, Nguyen PD, Mathes DW, Khechoyan D. Craniometrics in Metopic Craniosynostosis: A Review of Craniometric Parameters and the Emergence of Machine Learning Models. J Craniofac Surg. 2026 Jan 13. [Epub ahead of print] PubMed PMID: 41528319
• McCranie AS, Blades C, Dawson S, Foppiani JA, Allenby T, Winocour J, Cohen J, Mathes D, Kaoutzanis C. Abdominal Wall Reinforcement Using OviTex after Deep Inferior Epigastric Perforator Flap. J Reconstr Microsurg. 2026 Jan;42(1):44-52. PubMed PMID: 40068894
• Chaij JM, Hammond JB, Palmer SK, Lee AD, Gomez DA, French BM, Nguyen PD, Mathes DW, Khechoyan DY. Medicaid's Cranio-Cap: Medicaid Reimbursement for Craniosynostosis Repair is Not Trending With the Rate of Inflation. J Craniofac Surg. 2025 Jul-Aug 01;36(5):1547-1551. PubMed PMID: 40062936
• Christodoulou N, Secanho M, Kokosis G, Malgor RD, Winocour J, Yu JW, Mathes DW, Kaoutzanis C. Reply to the Letter to the Editor about the article "Capsular contracture in breast reconstruction: A systematic review and meta-analysis". J Plast Reconstr Aesthet Surg. 2025 Mar;102:520-521. PubMed PMID: 40054988
• Haas E, Garoosi K, Kalia N, Tin G, Lee A, Orfahli LM, Mathes DW, Kaoutzanis C, Cohen JB. Complications associated with abdominal incisional wound vacuum assisted closure following deep inferior epigastric perforator flap harvest for breast reconstruction: A single institution retrospective study. J Plast Reconstr Aesthet Surg. 2025 Apr;103:345-350. PubMed PMID: 40054295
• Chaij JM, Hammond JB, Palmer SK, Lee AD, Gomez DA, French BM, Nguyen PD, Mathes DW, Khechoyan DY. Is the Future of Cleft Care Financially Sustainable? An Economic Analysis of Inflation-Adjusted Reimbursements. Cleft Palate Craniofac J. 2025 Feb 27;:10556656251322608. [Epub ahead of print] PubMed PMID: 40017116
• Haas E, Christodoulou N, Secanho M, Kokosis G, Malgor RD, Winocour J, Yu JW, Mathes DW, Kaoutzanis C. Capsular Contracture After Breast Augmentation: A Systematic Review and Meta-Analysis. Aesthet Surg J Open Forum. 2025;7:ojaf003. PubMed PMID: 39989707
• Lee AD, Gomez DA, Le ELH, Palmer SK, French B, Nguyen PD, Mathes DW, Khechoyan DY. Surgical Complications After Fronto-orbital Advancement for Craniosynostosis: Analysis of a National Database. J Craniofac Surg. 2025 Mar-Apr 01;36(2):526-530. PubMed PMID: 39898655
• Lee AD, Murphy M, Tin G, Alder C, Chaij J, Porras A, Yu J, French B, Lowe K, Nguyen PD, Mathes D, Khechoyan D. Trends of Staged Versus Single-Stage Operations for Bilateral Cleft Lip Repair: Analysis of a National Database. J Craniofac Surg. 2025 Jun 1;36(4):1246-1248. PubMed PMID: 39878571
• Ma J, Wang Z, Mintzlaff D, Zhang H, Ramakrishna R, Davila E, Witkowski MT, Lucia MS, Schwartz MS, Pomfret EA, Mathes DW, Wang Z. Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia. Blood. 2025 Jan 30;145(5):508-519. PubMed PMID: 39561285
• Zhu KJ, Cho AM, Beckett JS, Macyszyn L, Mathes D, Nguyen P, Irwin T, Kaouzanis C, Yu JW. A Systematic Review of the Complications Associated with Free Fibular Flaps in Adult and Pediatric Spinal Reconstruction. J Reconstr Microsurg. 2025 Jul;41(6):521-530. PubMed PMID: 39362646
• Hammond JB, Tillotson M, Yoon Y, Meza Monge K, Esch EM, Madura JA 2nd, Pratap A, Winocour J, Mathes DW, Kaoutzanis C. Metabolic Bridge Therapy before Microvascular Breast Reconstruction in Morbidly Obese Patients: A Proof-of-Concept Risk Analysis. Plast Reconstr Surg. 2025 May 1;155(5):753-760. PubMed PMID: 39356702
• Blades CM, Greyson MA, Dumanian ZP, Yu JW, Wang Y, Li B, Wang Z, Washington KM, Huang CA, Navarro-Alvarez N, Mathes DW. Development of a Porcine VCA Model Using an External Iliac Vessel-Based Vertical Rectus Abdominus Myocutaneous Flap. J Reconstr Microsurg. 2025 May;41(4):339-346. PubMed PMID: 39106899
• Constantine RS, Foppiani JA, Allenby T, Kokosis G, Mathes DW, Winocour J, Kaoutzanis C. Purse-String DIEPplasty: A Technique to Improve Aesthetic Outcome of Autologous Breast Reconstruction. Aesthetic Plast Surg. 2025 Jan;49(1):164-168. PubMed PMID: 38992248
• Ma J, Ravindran Menon D, Wang Z, Mintzlaff D, Rock H, Giesy L, Huang CA, Mathes DW, Nydam T, Pomfret EA, Camidge DR, Sabaawy HE, Pine SR, Wang Z. Bivalent CD47 Immunotoxin for Targeted Therapy of Lung Cancer. bioRxiv. 2025 Dec 26. PubMed PMID: 41497639
• Driban JB, Rokoff LB, Lu B, McAlindon TE, Eaton CB, Roberts MB, Mathes D, Lestician C, Xu ZC, Fan ZT, O'Leary SP, Haugen IK, Sellam J, Courties A, Fleisch AF. Per- and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative. Arthritis Rheumatol. 2025 Dec 22. [Epub ahead of print] PubMed PMID: 41429602
• Escobar-Domingo MJ, Fanning JE, Posso A, Nguyen K, Thomas C, Karinja SJ, Lin SJ, Mathes DW, Lee BT, Kaoutzanis C. Multimetric Analysis of Online Health Resources for Oncoplastic Breast Surgery Patients. J Surg Res. 2025 Dec 11;317:208-216. [Epub ahead of print] PubMed PMID: 41385974
• Wallace AN, Aryanpour Z, Palmer SK, Blades CM, Kalia N, Mathes DW, Kaoutzanis C, Egan KG. "Characterizing Risk Factors for 30-Day Readmission in Autologous Breast Reconstruction Patients with DIEP Flaps". Plast Reconstr Surg. 2025 Dec 9. [Epub ahead of print] PubMed PMID: 41364625
• Green EA, Gomez DA, Yu JW, Palmer SK, Irwin TJ, French B, Nguyen PD, Mathes DW, Khechoyan DY. Telehealth Improves Access and Efficiency in Pediatric Plastic Surgery: A Study on Surgical Conversion Rates and Time to Surgery. J Craniofac Surg. 2025 Nov 24. [Epub ahead of print] PubMed PMID: 41284477
• Gehring MB, Wolfe B, Kalia N, Helmkamp LJ, Widner JL, Christian N, Tevis SE, Murphy CD, Cohen JB, Winocour JS, Mathes DW, Kaoutzanis C. Comparing Discharge Timing in Patients Undergoing Immediate Implant-Based Breast Reconstruction: A Randomized Controlled Trial. Plast Reconstr Surg. 2025 Nov 17. [Epub ahead of print] PubMed PMID: 41247168
• Lee AD, Le T, Yang JH, Johnson A, Winocour J, Iorio M, Chong T, Kaoutzanis C, Yu JW, Nguyen PD, Mathes D, Khechoyan DY. Surgical Outcomes After Scalp Reconstruction With Free Tissue Transfer. J Craniofac Surg. 2025 Nov 3. [Epub ahead of print] PubMed PMID: 41182844
• Hamzeh BF, Lee AD, French B, Nguyen P, Yu JW, Mathes DW, Khechoyan DY. Intraoperative Navigation in Orthognathic Surgery: Mitigating Iatrogenic Complications. J Craniofac Surg. 2025 Oct 20. [Epub ahead of print] PubMed PMID: 41118494
• Aryanpour Z, Cronin JE, Shah A, Yang JH, Haas EJ, Winocour J, Kaoutzanis C, Mathes DW, Egan KG. Perioperative Vitamin D Insufficiency Impacts Postoperative Outcomes in Abdominally Based Breast Reconstruction. Plast Reconstr Surg. 2025 Oct 6. [Epub ahead of print] PubMed PMID: 41051269
• Palmer SK, Shah A, Aryanpour Z, Le D, Winocour J, Kaoutzanis C, Mathes DW, Egan KG. Deep Inferior Epigastric Perforator In-Basket? Evaluation of Patient Electronic Communication Following Autologous Breast Reconstruction. Aesthet Surg J. 2025 Sep 9. [Epub ahead of print] PubMed PMID: 40922661
• Le DM, Hoffman GR, Silveira LJ, French B, Nguyen PD, Samples DC, Yu J, Ridder T, Mathes DW, Khechoyan D. A Retrospective Review of Craniosynostosis Reconstruction at a Community Children's Hospital Compared With Academic Centers. J Craniofac Surg. 2025 Sep 10. [Epub ahead of print] PubMed PMID: 40929651
• Lee AD, Palmer SK, Gomez DA, Le E, Green EA, Alexander A, Wilkinson C, Alshareef M, Porras AR, Yu J, Irwin TJ, French B, Nguyen PD, Mathes D, Khechoyan DY. Secondary Cranioplasty After Fronto-Orbital Advancement: Analysis of a National Database. J Craniofac Surg. 2025 Sep 1. [Epub ahead of print] PubMed PMID: 40888846
• Aryanpour Z, Wallace A, Winocour J, Mathes DW, Kaoutzanis C, Egan KG. Abdominal Peripheral Nerve Blocks Do Not Impact Postoperative Pain in Free Flap Breast Reconstruction. J Reconstr Microsurg. 2025 Aug 14. [Epub ahead of print] PubMed PMID: 40812342
• Haas EJ, Hamzeh BF, Aryanpour Z, Yu JW, Mathes DW, Kaoutzanis C. Improving the Patient Experience in Breast Reconstruction: ERAS and Beyond. J Clin Med. 2025 Aug 7;14(15). PubMed PMID: 40807212
• McCranie AS, Haas EJ, Aryanpour Z, Egan KG, Yu JW, Winocour J, Mathes DW, Kaoutzanis C. Telehealth and plastic surgery: evaluation of the accessibility of virtual consultations through online resources. Mhealth. 2025;11:33. PubMed PMID: 40755933
• Garoosi K, Kalia N, Adepoju J, Escobar-Domingo MJ, Horstman C, Kahan R, Fitzpatrick Q, Ahn YJ, Park JB, Grobman B, Lee D, Shenaq DS, Kurlander D, Raj M, Tevis S, Arruda J, Winocour J, Kokosis G, Lee BT, Mathes DW, Kaoutzanis C. Post-operative complications in combined versus staged breast reconstruction and risk-reducing gynecologic surgeries: A multi-institution multi-surgeon analysis. J Plast Reconstr Aesthet Surg. 2025 Aug;107:258-266. PubMed PMID: 40617763
• Lee AD, Palmer SK, Hammond JB, Yoon Y, Lee N, Le ELH, Gomez DA, Kaoutzanis C, Yu JW, French B, Nguyen PD, Mathes DW, Khechoyan DY. Concomitant Facial Fractures: A National Evaluation of Patients, Prevalence, and Fracture Patterns. J Craniofac Surg. 2025 Jun 30. [Epub ahead of print] PubMed PMID: 40587766
• Gomez DA, Blades CM, Haas EJ, Aryanpour Z, Mathes DW, Nguyen PD, Egan KG. Incentive to Publish in Plastic Surgery: Does It Continue After the Match?. Ann Plast Surg. 2025 Aug 1;95(2):201-205. PubMed PMID: 40549938
• Palmer SK, Wallace AN, Park Chang JB, Aryanpour Z, Carey JN, Greyson MA, Mathes DW, Nguyen PD. The Continued Value of the Independent Training Pathway and Impact on Career Trajectory. Plast Reconstr Surg Glob Open. 2025 Jun;13(6):e6835. PubMed PMID: 40469544
• Aryanpour Z, McCranie AS, Yu JW, Winocour J, Egan KG, Mathes D, Kaoutzanis C. A Scoping Review of Precision Medicine in Breast Reconstruction (2011-2025). J Pers Med. 2025 Apr 28;15(5). PubMed PMID: 40423050
• Gomez DA, Lee AD, Le ELH, Kaoutzanis C, Palmer SK, Yu JW, French B, Mathes DW, Nguyen PD, Khechoyan DY. Billing Practices in Pediatric Fronto-Orbital Advancement Surgeries: Review of a National Billing Database. J Craniofac Surg. 2025 Jul-Aug 01;36(5):1711-1714. PubMed PMID: 40392074
• Gomez DA, Lee AD, Hammond JB, Palmer SK, French B, Yu JW, Nguyen PD, Mathes DW, Khechoyan DY. Early-Onset Facial Weakness: Evaluation and Surgical Treatment of Facioscapulohumeral Muscular Disease. J Craniofac Surg. 2025 Jul-Aug 01;36(5):1758-1762. PubMed PMID: 40392070
• Gomez DA, Green EA, Lee AD, Palmer SK, French B, Yu JW, Nguyen PD, Mathes DW, Khechoyan DY. Litigation in Craniofacial Surgery in the US: An Analysis of Lawsuits Over 4 Decades. J Craniofac Surg. 2025 Jul-Aug 01;36(5):1570-1574. PubMed PMID: 40392069
• Mathes D, Bueno Macedo L, Baldissera Pieta T, Costa Maia B, Bueno Rolim CM, Rubert Nogueira-Librelotto D. The role of polymer type and surfactant composition on the toxicological profile of nanoparticles: an in vitro comparative study. J Biomater Sci Polym Ed. 2025 Sep;36(13):1853-1870. PubMed PMID: 40193339
• Blades CM, Dumanian ZP, Wang Y, Wang Z, Li B, Washington KM, Slade JB, Evans CL, Arrowsmith P, Farkash EA, Yu JW, Greyson MA, Huang CA, Navarro-Alvarez N, Mathes DW. Autologous porcine VRAM flap model for VCA research. Front Transplant. 2024;3:1504959. PubMed PMID: 39712036
• Ma J, Wang Z, Mintzlaff D, Zhang H, Ramakrishna R, Davila E, Witkowski MT, Lucia MS, Schwartz MS, Pomfret EA, Mathes DW, Wang Z. Bivalent CD47 Immunotoxin for Targeted Therapy of T-Cell Acute Lymphoblastic Leukemia. Blood. 2024 Nov 19. [Epub ahead of print] PubMed PMID: 39561285
• Rodriguez MM, Swiekatowski KR, Tung RC, Greives MR, Mathes DW, Nguyen PD. Where Do Plastic Surgery Leaders Come From? A Cross-sectional Analysis of Research Productivity. Plast Reconstr Surg Glob Open. 2024 Aug;12(8):e6013. PubMed PMID: 39534072
• Godbe KN, Sinik LM, Guest R, Nazir N, Egan K, Mathes D, Farmer R, Butterworth J. Application Discrepancies in the 2023-2024 Integrated Plastic Surgery Match. Ann Plast Surg. 2024 Dec 1;93(6):701-706. PubMed PMID: 39526816
• Blades CM, Huang CA, Mathes DW. The current state of tolerance induction in vascularized composite allotransplantation. Curr Opin Organ Transplant. 2024 Dec 1;29(6):368-375. PubMed PMID: 39422587
• Zhu KJ, Cho AM, Beckett JS, Macyszyn L, Mathes D, Nguyen P, Irwin T, Kaouzanis C, Yu JW. A Systematic Review of the Complications Associated with Free Fibular Flaps in Adult and Pediatric Spinal Reconstruction. J Reconstr Microsurg. 2024 Oct 30. [Epub ahead of print] PubMed PMID: 39362646
• Hammond JB, Tillotson M, Yoon Y, Meza Monge K, Esch EM, Madura JA 2nd, Pratap A, Winocour J, Mathes DW, Kaoutzanis C. "Metabolic Bridge Therapy Prior to Microvascular Breast Reconstruction in the Morbidly Obese: A Proof-of-Concept Risk Analysis". Plast Reconstr Surg. 2024 Oct 1. [Epub ahead of print] PubMed PMID: 39356702
• Godbe KN, Sinik LM, Nazir N, Egan K, Mathes D, Butterworth J, Farmer R. The Effect of Numeric Versus Pass/Fail USMLE Step 1 Scores in the Integrated Plastic Surgery 2023-2024 Match Cycle: A Single Institution Study. J Surg Educ. 2024 Nov;81(11):1667-1674. PubMed PMID: 39288510
• Christodoulou N, Secanho M, Kokosis G, Malgor RD, Winocour J, Yu JW, Mathes DW, Kaoutzanis C. Capsular contracture in breast reconstruction: A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2024 Nov;98:131-143. PubMed PMID: 39244792
• Blades CM, Greyson MA, Dumanian ZP, Yu JW, Wang Y, Li B, Wang Z, Washington KM, Huang CA, Navarro-Alvarez N, Mathes DW. Development of a Porcine VCA Model Using an External Iliac Vessel-Based Vertical Rectus Abdominus Myocutaneous Flap. J Reconstr Microsurg. 2024 Aug 6. [Epub ahead of print] PubMed PMID: 39106899
• McCranie A, Lee AD, Cyrus C, Desjardins H, Winocour J, Mathes D, Kaoutzanis C. Evaluation of the Impact of Physical Therapy on Patients With Macromastia Seeking Breast Reduction Surgery. Aesthet Surg J. 2024 Nov 15;44(12):NP862-NP869. PubMed PMID: 39041881
• Giannas E, Winocour J, Yu J, Kokosis G, Mathes D, Kaoutzanis C. The effect of antibiotic beads on periprosthetic infection in implant-based breast reconstruction following mastectomy. J Plast Reconstr Aesthet Surg. 2024 Sep;96:33-35. PubMed PMID: 39024678
• Constantine RS, Foppiani JA, Allenby T, Kokosis G, Mathes DW, Winocour J, Kaoutzanis C. Purse-String DIEPplasty: A Technique to Improve Aesthetic Outcome of Autologous Breast Reconstruction. Aesthetic Plast Surg. 2024 Jul 11. [Epub ahead of print] PubMed PMID: 38992248
• Garoosi K, Yoon Y, Hale E, Kahan R, Kalia N, Higuchi T, Mathes D, Hudish T, Kaoutzanis C. Association between genital gender-affirming surgery and psychiatric comorbidities in individuals with gender incongruence. J Sex Med. 2024 Aug 1;21(8):729-733. PubMed PMID: 38972664
• Low Wang CC, Chong T, Moore G, Echalier B, Haakonsen N, Carter JE Jr, Mathes D, Hsia J, Phan TT, Lim IJ, Freed BM. Results of the Phase 1 Open-Label Safety Study of Umbilical Cord Lining Mesenchymal Stromal/Stem Cells (Corlicyte(®)) to Heal Chronic Diabetic Foot Ulcers. Biomedicines. 2024 Jun 20;12(6). PubMed PMID: 38927582
• Mathes D, Macedo LB, Pieta TB, Maia BC, Rodrigues OED, Leal JG, Wendt M, Rolim CMB, Mitjans M, Nogueira-Librelotto DR. Co-Delivery of an Innovative Organoselenium Compound and Paclitaxel by pH-Responsive PCL Nanoparticles to Synergistically Overcome Multidrug Resistance in Cancer. Pharmaceutics. 2024 Apr 26;16(5). PubMed PMID: 38794252
• Ng PK, Yoeli D, Huang JL, Luo Y, Wang Y, Li B, Wang Z, Schold J, Jain S, Su AA, Mathes DW, Washington KM, Farkash E, Jani AH, Huang CA. Successful Extension of Vascularized Composite Allograft Perfusion Cold Storage to 24 h in a Rat Hindlimb Transplant Model. Transplant Direct. 2024 Jun;10(6):e1623. PubMed PMID: 38757052
• McCranie AS, Desjardins HE, Allenby TH, Mathes DW, Wong CJ. Patient Satisfaction Using BREAST-Q and Breast Implant Illness after Breast Reconstruction in Transwomen. Plast Reconstr Surg Glob Open. 2024 May;12(5):e5787. PubMed PMID: 38741598
• Foppiani JA, Kim E, Weidman AA, Alvarez AH, Escobar-Domingo MJ, Valentine L, Lee TC, Mathes DW, Lee BT, Lin SJ. Continuing Insurance Coverage for Flap-Based Breast Reconstruction: Is There a Reservation Cost Related to a Woman's Abdominal Flap Choice?. Ann Plast Surg. 2024 Apr 1;92(4S Suppl 2):S228-S233. PubMed PMID: 38556679
• Hammond JB, Mathes DW, Winocour J, Kaoutzanis C. Shrinking Waistlines and Shrinking Complications: Can Bariatric Surgery Optimize the Morbidly Obese for Microvascular Breast Reconstruction?. Aesthet Surg J. 2024 Jun 14;44(7):NP527-NP528. PubMed PMID: 38526311
• Ha A, Garoosi K, Hale E, Higuchi T, Winocour J, Mathes DW, Kaoutzanis C. Trends in Gender-Affirming Surgeries in the United States from 2010 to 2021. Indian J Plast Surg. 2024 Feb;57(1):47-53. PubMed PMID: 38450014
• McCranie AS, Christodoulou N, Wolfe B, Malgor RD, Mathes DW, Winocour J, Yu JW, Kalia N, Kaoutzanis C. The use of flaps for management of deep sternal wound complications: A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2024 Apr;91:302-311. PubMed PMID: 38442510
• Garoosi K, Yoon Y, Winocour J, Mathes DW, Kaoutzanis C. The Effects of Body Mass Index on Postoperative Complications in Patients Undergoing Autologous Free Flap Breast Reconstruction. J Reconstr Microsurg. 2024 Oct;40(8):601-610. PubMed PMID: 38395056
• Wang Z, Ramakrishna R, Wang Y, Qiu Y, Ma J, Mintzlaff D, Zhang H, Li B, Hammell B, Lucia MS, Pomfret E, Su AA, Washington KM, Mathes DW, Wang Z. Toxicology, pharmacokinetics, and immunogenicity studies of CCR4-IL2 bispecific immunotoxin in rats and minipigs. Eur J Pharmacol. 2024 Apr 5;968:176408. PubMed PMID: 38367684
• Fisher MH, Ohmes LB, Yang JH, Le E, Colakoglu S, French M, Siddikoglu D, Um G, Winocour J, Higdon K, Perdikis G, Inchauste S, Cohen J, Chong T, Kaoutzanis C, Mathes DW. Abdominal donor-site complications following autologous breast reconstruction: A multi-institutional multisurgeon study. J Plast Reconstr Aesthet Surg. 2024 Mar;90:88-94. PubMed PMID: 38364673
• Christodoulou N, Wolfe B, Mathes DW, Malgor RD, Kaoutzanis C. Vacuum-assisted closure therapy for the management of deep sternal wound complications: A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2024 Jul;94:251-260. PubMed PMID: 37951723
• Tuaño KR, Yang JH, Fisher MH, Le E, Khatter NJ, Kalia N, Colakoglu S, Cohen JB, Kaoutzanis C, Chong TW, Mathes DW. Venous Thromboembolism after DIEP Flap Breast Reconstruction: Review of Outcomes after a Postoperative Prophylaxis Protocol. Plast Reconstr Surg. 2024 Jul 1;154(1):13e-20e. PubMed PMID: 37506353
• Qiu Y, Qi Z, Wang Z, Cao Y, Lu L, Zhang H, Mathes D, Pomfret EA, Lu SL, Wang Z. EGF-IL2 bispecific and bivalent EGF fusion toxin efficacy against syngeneic head and neck cancer mouse models. Oncol Rep. 2023 Feb;49(2). PubMed PMID: 36579667
• Aravind P, Colakoglu S, Bhoopalam M, Ibrahim A, Mathes D, Kaoutzanis C, Mureau M, Reddy S. Perforator Characteristics and Impact on Postoperative Outcomes in DIEP Flap Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2023 Feb;39(2):138-147. PubMed PMID: 35714621
• Christodoulou N, Wolfe B, Mathes DW, Malgor RD, Kaoutzanis C. Vacuum-assisted closure therapy for the management of deep sternal wound complications: A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2023 Oct 17. [Epub ahead of print] PubMed PMID: 37951723
• Lee AD, Hale EW, Mundra L, Le E, Kaoutzanis C, Mathes DW. The heart of it all: Body dysmorphic disorder in cosmetic surgery. J Plast Reconstr Aesthet Surg. 2023 Dec;87:442-448. PubMed PMID: 37944455
• Yang JH, Huynh V, Leonard LD, Kovar A, Bronsert M, Ludwigson A, Wolverton D, Hampanda K, Christian N, Kim SP, Ahrendt G, Mathes DW, Tevis SE. Are Diagnostic Delays Associated with Distress in Breast Cancer Patients?. Breast Care (Basel). 2023 Aug;18(4):240-248. PubMed PMID: 37900555
• Garoosi K, Mundra L, Jabbari K, Winocour J, Iorio ML, Mathes DW, Kaoutzanis C. Comorbid Conditions and Complications in Body Contouring Surgery: A Retrospective Review. Aesthet Surg J Open Forum. 2023;5:ojad080. PubMed PMID: 37711766
• Garoosi K, Lee N, Tuano KR, Lee ELH, Cohen J, Winocour J, Mathes DW, Iorio ML, Kaoutzanis C. Analysis of Complications in Patients With a History of Cannabis Use and Tobacco Use Undergoing Implant-Based Breast Reconstruction. Aesthet Surg J. 2023 Dec 14;44(1):NP41-NP48. PubMed PMID: 37706275
• Jacobson NM, Carerra E, Treat A, McDonnell M, Mathes D, Kaoutzanis C. Hybrid modeling techniques for 3D printed deep inferior epigastric perforator flap models. 3D Print Med. 2023 Sep 12;9(1):26. PubMed PMID: 37700101
• Tuaño KR, Yang JH, Fisher MH, Le E, Khatter NJ, Kalia N, Colakoglu S, Cohen JB, Kaoutzanis C, Chong TW, Mathes DW. Venous Thromboembolism after Deep Inferior Epigastric Perforator Flap Breast Reconstruction: Review of Outcomes After a Postoperative Prophylaxis Protocol. Plast Reconstr Surg. 2023 Jul 25. [Epub ahead of print] PubMed PMID: 37506353
• Yoon Y, Lee N, Lee AD, Gehring MB, Constantine R, Mathes DW, Yu JW, Khechoyan D, Iorio ML, Kaoutzanis C. Analysis of postoperative complications related to cannabis and tobacco usage in patients undergoing mandible facial fracture surgeries. J Plast Reconstr Aesthet Surg. 2023 Oct;85:127-133. PubMed PMID: 37482026
• McCranie A, Desjardins H, Mathes D, Kaoutzanis C. Should Physical Therapy Be an Insurance Requirement for Patients Seeking a Breast Reduction?. Aesthet Surg J. 2023 Aug 17;43(9):NP713-NP714. PubMed PMID: 37185654
• Mundra L, Garossi K, Iorio M, Mathes D, Winocour J, Kaoutzanis C. Opioid-Prescribing Patterns in Body Contouring Surgery. Aesthet Surg J. 2023 Aug 17;43(9):978-985. PubMed PMID: 37185594
• Wang Z, Ma J, Zhang H, Ramakrishna R, Mintzlaff D, Mathes DW, Pomfret EA, Lucia MS, Gao D, Haverkos BM, Wang Z. CCR4-IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T-cell lymphoma in a mouse CTCL model. FEBS Open Bio. 2023 Jul;13(7):1309-1319. PubMed PMID: 37157185
• Jabbari K, Gehring MB, Iorio ML, Mathes DW, Kaoutzanis C. Macromastia and Reduction Mammaplasty: Analysis of Outpatient Cost of Care and Opioid Consumption at 5 Years Postoperatively. Aesthet Surg J. 2023 Sep 14;43(10):NP763-NP770. PubMed PMID: 37071801
• Khavanin N, Yang JH, Colakoglu S, Tuano KR, Wong JO, Cohen JB, Chong TW, Reddy S, Mathes DW, Kaoutzanis C. Breast Reconstruction Trends in the Setting of Postmastectomy Radiation Therapy: Analysis of Practices among Plastic Surgeons in the United States. Plast Reconstr Surg Glob Open. 2023 Feb;11(2):e4800. PubMed PMID: 36817273
• Le ELH, Saifee J, Constantine R, Tuaño K, Yang J, Kaoutzanis C, Mathes DW, Iorio ML. Extended Venous Thromboembolism Chemoprophylaxis following Microsurgical Breast Reconstruction: Analysis of Trends in Postoperative Anticoagulation. Plast Reconstr Surg. 2023 Jul 1;152(1):20-27. PubMed PMID: 36728476
• Qiu Y, Qi Z, Wang Z, Cao Y, Lu L, Zhang H, Mathes D, Pomfret EA, Lu SL, Wang Z. EGF-IL2 bispecific and bivalent EGF fusion toxin efficacy against syngeneic head and neck cancer mouse models. Oncol Rep. 2023 Feb;49(2). PubMed PMID: 36579667
• Aravind P, Colakoglu S, Bhoopalam M, Ibrahim A, Mathes D, Kaoutzanis C, Mureau M, Reddy S. Perforator Characteristics and Impact on Postoperative Outcomes in DIEP Flap Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2023 Feb;39(2):138-147. PubMed PMID: 35714621
• Johnson AC, Colakoglu S, Siddikoglu D, Li A, Kaoutzanis C, Cohen JB, Chong TW, Mathes DW. Impact of Dermal Matrix Brand in Implant-Based Breast Reconstruction Outcomes. Plast Reconstr Surg. 2022 Jul 1;150(1):17-25. PubMed PMID: 35499525
• Yang JH, Colakoglu S, Mureau MAM, Siddikoglu D, Johnson AC, Cohen JB, Lee BT, Chong TW, Mathes DW, Kaoutzanis C. Midline epigastric scars can be associated with higher umbilical complications following DIEP flap harvest. J Plast Reconstr Aesthet Surg. 2022 Jun;75(6):1826-1832. PubMed PMID: 35172949
• Colakoglu S, Tebockhorst S, Freedman J, Douglass S, Siddikoglu D, Chong TW, Mathes DW. CT angiography prior to DIEP flap breast reconstruction: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):45-51. PubMed PMID: 34332925
• Schols RM, Dip F, Lo Menzo E, Haddock NT, Landin L, Lee BT, Malagón P, Masia J, Mathes DW, Nahabedian MY, Neligan PC, Newman MI, Phillips BT, Pons G, Pruimboom T, Qiu SS, Ritschl LM, Rozen WM, Saint-Cyr M, Song SY, van der Hulst RRWJ, Venturi ML, Wongkietkachorn A, Yamamoto T, White KP, Rosenthal RJ. Delphi survey of intercontinental experts to identify areas of consensus on the use of indocyanine green angiography for tissue perfusion assessment during plastic and reconstructive surgery. Surgery. 2022 Dec;172(6S):S46-S53. PubMed PMID: 36427930
• Tuano KR, Yang JH, Kleck CJ, Mathes DW, Chong TW. Multidisciplinary Treatment of Persistent Nontuberculous Mycobacterial Spinal Hardware Infection with a Pedicled Superior Gluteal Artery Perforator Flap. Arch Plast Surg. 2022 Sep;49(5):604-607. PubMed PMID: 36159388
• Rhee DH, Constantine RS, Colakoglu S, Karimpour-Fard A, Kaoutzanis C, Mathes DW, Chong TW. Clinical outcomes of intraoperative dopamine infusion for hypotensive patients during breast reconstruction with deep inferior epigastric perforator (DIEP) flaps. J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):2982-2990. PubMed PMID: 35915016
• Colakoglu S, Yang J, French MM, Winocour J, Um GT, Blumenauer B, Siddikoglu D, Mureau MAM, Chong T, Higdon K, Perdikis G, Inchauste SM, Kaoutzanis C, Mathes DW. Importance of Incidental Findings in Preoperative Computed Tomography Angiography for Abdominally Based Free Flap Breast Reconstruction: A Multi-Institutional Study. Plast Reconstr Surg. 2022 Sep 1;150(3):527-535. PubMed PMID: 35748758
• Johnson AC, Colakoglu S, Siddikoglu D, Li A, Kaoutzanis C, Cohen JB, Chong TW, Mathes DW. Impact of Dermal Matrix Brand in Implant-Based Breast Reconstruction Outcomes. Plast Reconstr Surg. 2022 Jul 1;150(1):17-25. PubMed PMID: 35499525
• Yang JH, Colakoglu S, Mureau MAM, Siddikoglu D, Johnson AC, Cohen JB, Lee BT, Chong TW, Mathes DW, Kaoutzanis C. Midline epigastric scars can be associated with higher umbilical complications following DIEP flap harvest. J Plast Reconstr Aesthet Surg. 2022 Jun;75(6):1826-1832. PubMed PMID: 35172949
• Colakoglu S, Tebockhorst S, Freedman J, Douglass S, Siddikoglu D, Chong TW, Mathes DW. CT angiography prior to DIEP flap breast reconstruction: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):45-51. PubMed PMID: 34332925
• Schols RM, Dip F, Lo Menzo E, Haddock NT, Landin L, Lee BT, Malagón P, Masia J, Mathes DW, Nahabedian MY, Neligan PC, Newman MI, Phillips BT, Pons G, Pruimboom T, Qiu SS, Ritschl LM, Rozen WM, Saint-Cyr M, Song SY, van der Hulst RRWJ, Venturi ML, Wongkietkachorn A, Yamamoto T, White KP, Rosenthal RJ. Delphi survey of intercontinental experts to identify areas of consensus on the use of indocyanine green angiography for tissue perfusion assessment during plastic and reconstructive surgery. Surgery. 2022 Dec;172(6S):S46-S53. PubMed PMID: 36427930
• Tuano KR, Yang JH, Kleck CJ, Mathes DW, Chong TW. Multidisciplinary Treatment of Persistent Nontuberculous Mycobacterial Spinal Hardware Infection with a Pedicled Superior Gluteal Artery Perforator Flap. Arch Plast Surg. 2022 Sep;49(5):604-607. PubMed PMID: 36159388
• Rhee DH, Constantine RS, Colakoglu S, Karimpour-Fard A, Kaoutzanis C, Mathes DW, Chong TW. Clinical outcomes of intraoperative dopamine infusion for hypotensive patients during breast reconstruction with deep inferior epigastric perforator (DIEP) flaps. J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):2982-2990. PubMed PMID: 35915016
• Colakoglu S, Yang J, French MM, Winocour J, Um GT, Blumenauer B, Siddikoglu D, Mureau MAM, Chong T, Higdon K, Perdikis G, Inchauste SM, Kaoutzanis C, Mathes DW. Importance of Incidental Findings in Preoperative Computed Tomography Angiography for Abdominally Based Free Flap Breast Reconstruction: A Multi-Institutional Study. Plast Reconstr Surg. 2022 Sep 1;150(3):527-535. PubMed PMID: 35748758
• Colakoglu S, Tebockhorst S, Freedman J, Douglass S, Siddikoglu D, Chong TW, Mathes DW. CT angiography prior to DIEP flap breast reconstruction: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):45-51. PubMed PMID: 34332925
• Anderson JB, Foglio A, Harrant AB, Huang CA, Hultman CS, Mathes DW, Chong TW. Scoping Review of Therapeutic Strategies for Keloids and Hypertrophic Scars. Plast Reconstr Surg Glob Open. 2021 Mar;9(3):e3469. PubMed PMID: 33786262
• Colakoglu S, Johnson A, Mureau MAM, Douglass S, Kaoutzanis C, Chong TW, Mathes DW, Cohen JB. Telehealth: Could It Be an Avenue to Microvascular Breast Reconstruction for Patients with Geographical Barriers?. J Reconstr Microsurg. 2021 Sep;37(7):597-601. PubMed PMID: 33592632
• Qi Z, Qiu Y, Wang Z, Zhang H, Lu L, Liu Y, Mathes D, Pomfret EA, Gao D, Lu SL, Wang Z. A novel diphtheria toxin-based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma. Mol Oncol. 2021 Apr;15(4):1054-1068. PubMed PMID: 33540470
• Yang JH, Johnson AC, Colakoglu S, Huang CA, Mathes DW. Clinical and preclinical tolerance protocols for vascularized composite allograft transplantation. Arch Plast Surg. 2021 Nov;48(6):703-713. PubMed PMID: 34818720
• Johnson AC, King BBT, Colakoglu S, Yang JH, Chong TW, Mathes DW. The Influence of Closing the Abdominal Donor-Site Superficial Fascial System in Deep Inferior Epigastric Perforator Flap Breast Reconstruction. Plast Reconstr Surg. 2021 Sep 1;148(3):357e-364e. PubMed PMID: 34432680
• Johnson AC, Colakoglu S, Chong TW, Mathes DW. Indocyanine Green Angiography in Breast Reconstruction: Utility, Limitations, and Search for Standardization. Plast Reconstr Surg Glob Open. 2020 Mar;8(3):e2694. PubMed PMID: 32537350
• Colakoglu S, Johnson A, Anderson J, Mathes DW, Chong TW. Changes to Venous Flow Coupler Signal during DIEP Flap Inset Can Be Predictive of Poor Clinical Outcomes in Autologous Breast Reconstruction. J Reconstr Microsurg. 2020 Jul;36(6):466-470. PubMed PMID: 32172526
• Wang H, Wang Z, Zhang H, Qi Z, Johnson AC, Mathes D, Pomfret EA, Rubin E, Huang CA, Wang Z. Bispecific human IL2-CCR4 immunotoxin targets human cutaneous T-cell lymphoma. Mol Oncol. 2020 May;14(5):991-1000. PubMed PMID: 32107846
• Colakoglu S, Tebockhorst S, Mathes DW. Is Vascularized Composite Allograft Transplantation Experimental or an Accepted Surgical Procedure: Results from a National Survey. J Reconstr Microsurg. 2020 May;36(4):276-280. PubMed PMID: 31986534
• Colakoglu S, Tebockhorst S, Chong TW, Mathes DW. Patient Safety in Microvascular Plastic Surgery. J Reconstr Microsurg. 2019 Nov;35(9):631-639. PubMed PMID: 31327160
• Shah NR, Cohen WA, Ayyala HS, Sorkin J, Mathes D, Ignatiuk A. Bilateral Cross Arm Flaps for Resurfacing Hands After High-Voltage Injury. Eplasty. 2019;19:ic2. PubMed PMID: 30680049
• LaRanger R, Karimpour-Fard A, Costa C, Mathes D, Wright WE, Chong T. Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. Plast Reconstr Surg. 2019 Feb;143(2):490-494. PubMed PMID: 30531622
• LaRanger R, Karimpour-Fard A, Costa C, Mathes D, Wright WE, Chong T. Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. Plast Reconstr Surg. 2018 Nov 26. [Epub ahead of print] PubMed PMID: 30531622
• Smith JM, Broyles JM, Guo Y, Tuffaha SH, Mathes D, Sacks JM. Human acellular dermis increases surgical site infection and overall complication profile when compared with submuscular breast reconstruction: An updated meta-analysis incorporating new products(?). J Plast Reconstr Aesthet Surg. 2018 Nov;71(11):1547-1556. PubMed PMID: 30093286
• Sousa J, Sood R, Liu D, Calhoun K, Louie O, Neligan P, Said H, Mathes D. Comparison of Outcomes in Immediate Implant-Based Breast Reconstruction Versus Mastectomy Alone. Plast Surg (Oakv). 2018 Feb;26(1):18-25. PubMed PMID: 29619355
• Gougoutas AJ, Said HK, Um G, Chapin A, Mathes DW. Nipple-Areola Complex Reconstruction. Plast Reconstr Surg. 2018 Mar;141(3):404e-416e. PubMed PMID: 29481412
• Heelan Gladden AA, Sams S, Gleisner A, Finlayson C, Kounalakis N, Hosokawa P, Brown R, Chong T, Mathes D, Murphy C. Discussion of: "Re-excision rates after breast conserving surgery following the 2014 SSO-ASTRO guidelines". Am J Surg. 2017 Dec;214(6):1110-1111. PubMed PMID: 29033142
• Chang J, Graves SS, Butts-Miwongtum T, Sale GE, Storb R, Mathes DW. Long-term Tolerance Toward Haploidentical Vascularized Composite Allograft Transplantation in a Canine Model Using Bone Marrow or Mobilized Stem Cells. Transplantation. 2016 Dec;100(12):e120-e127. PubMed PMID: 27861292
• Miranda SG, Liu Y, Morrison SD, Sood RF, Gallagher T, Gougoutas AJ, Colohan SM, Louie O, Mathes DW, Neligan PC, Said HK. Improved healthcare economic outcomes after liposomal bupivacaine administration in first-stage breast reconstruction. J Plast Reconstr Aesthet Surg. 2016 Oct;69(10):1456-7. PubMed PMID: 27475335
• Sandvall BK, Suver DW, Said HK, Mathes DW, Neligan PC, Dellinger EP, Louie O. Comparison of Synthetic and Biologic Mesh in Ventral Hernia Repair Using Components Separation Technique. Ann Plast Surg. 2016 Jun;76(6):674-9. PubMed PMID: 25003419
• Combs PD, Sousa JD, Louie O, Said HK, Neligan PC, Mathes DW. Comparison of vertical and oblique rectus abdominis myocutaneous flaps for pelvic, perineal, and groin reconstruction. Plast Reconstr Surg. 2014 Aug;134(2):315-23. PubMed PMID: 25068330
• Sandvall BK, Suver DW, Said HK, Mathes DW, Neligan PC, Dellinger EP, Louie O. Comparison of Synthetic and Biologic Mesh in Ventral Hernia Repair Using Components Separation Technique. Ann Plast Surg. 2014 Jul 4. [Epub ahead of print] PubMed PMID: 25003419
• Mathes DW, Solari MG, Gazelle GS, Butler PE, Wu A, Nazzal A, Nielsen GP, Huang CA, Sachs DH, Lee WP, Randolph MA. Stable mixed hematopoietic chimerism permits tolerance of vascularized composite allografts across a full major histocompatibility mismatch in swine. Transpl Int. 2014 Oct;27(10):1086-96. PubMed PMID: 24963743
• Mathes DW, Chang J, Hwang B, Graves SS, Storer BE, Butts-Miwongtum T, Sale GE, Storb R. Simultaneous transplantation of hematopoietic stem cells and a vascularized composite allograft leads to tolerance. Transplantation. 2014 Jul 27;98(2):131-8. PubMed PMID: 24918616
• Mathes DW, Edwards JA, Anzai Y, Neligan PC. A functional periorbital subunit allograft: vascular, anatomic, and technical considerations for future subunit facial transplantation. J Plast Reconstr Aesthet Surg. 2014 Oct;67(10):1371-7. PubMed PMID: 24917373
• Um GT, Chang J, Louie O, Colohan SM, Said HK, Neligan PC, Mathes DW. Implantable Cook-Swartz Doppler probe versus Synovis Flow Coupler for the post-operative monitoring of free flap breast reconstruction. J Plast Reconstr Aesthet Surg. 2014 Jul;67(7):960-6. PubMed PMID: 24767693
• Liu DZ, Mathes DW, Neligan PC, Said HK, Louie O. Comparison of outcomes using AlloDerm versus FlexHD for implant-based breast reconstruction. Ann Plast Surg. 2014 May;72(5):503-7. PubMed PMID: 23636114

Practice Locations

UCHealth Plastic and Reconstructive Surgery Clinic - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-0800

CU Medicine Plastic and Reconstructive Surgery - Highlands Ranch Specialty Care Center
1500 Park Central Drive
Suite 201
Highlands Ranch, CO 80129
720-516-4085

CU Medicine Cosmetic Surgery
12348 E. Montview Blvd
CU Anschutz Health and Wellness Center, 2nd floor
Aurora, CO 80045
303-724-8700

Rocky Mountain Regional Veterans Administration Medical Center
1700 Wheeling St
Aurora, CO 80045
303-399-8020

Hospital Affiliation

• University of Colorado Hospital
• UCHealth Highlands Ranch Hospital
• Veterans Affairs Medical Center

Center Affiliations

• Anschutz Health & Wellness Center

Specialty Information

Specialties

• Surgery, Board Certification (2005)
• Plastic Surgery, Board Certification (2007)

Conditions & Treatments

• Surgery
• Surgery - Breast Surgery
• Surgery - Free flaps and limb salvage
• Surgery - Bariatric Surgery - Weight Loss
• Surgery - Plastic, Reconstructive and Aesthetic Surgery
• Surgery - Gender Affirmation Surgery for Adults
• Cancers - Breast Cancer
• Cancers