Jennifer Black, MD

Professional Titles

• Chair, Pediatric Pathology
• Vice Chair, Pediatric Pathology
• Director, Pediatric Pathology Fellowship Program

Recognitions

• Young Investigator Award, Children's Oncology Group (2012)

Publications

• Hata JL, Black JO, Correa H, Esbenshade AJ, Chung DH, Mobley B. Diagnostic utility of PHOX2B in primary and treated neuroblastoma and in neuroblastoma metastatic to the bone marrow. Archives Pathol Lab Med.
• Coffin CM, Cajaiba MM, Correa H, Lyle P, Black JO. "Pediatric Tumors." In: David J. Dabbs, ed. Diagnostic Immunohistochemistry: Theranostic and Genomic Applications. 4th ed. Philadelphia, PA. Elsevier Sanders;2014.
• Quiroga-Garza G, Lee JH, El-Naggar A, Black JO, Amrikachi M, Zhai QJ, Ayala AG, Ro JY. Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: more aggressive than previously reported. Hum Pathol. 2015 May;46(5):725-31. PubMed PMID: 25754017
• Chen S, Grover M, Sibai T, Black J, Rianon N, Rajagopal A, Munivez E, Bertin T, Dawson B, Chen Y, Jiang MM, Lee B, Yang T, Bae Y. Losartan increases bone mass and accelerates chondrocyte hypertrophy in developing skeleton. Mol Genet Metab. 2015 May;115(1):53-60. PubMed PMID: 25779879
• Hata JL, Correa H, Krishnan C, Esbenshade AJ, Black JO, Chung DH, Mobley BC. Diagnostic utility of PHOX2B in primary and treated neuroblastoma and in neuroblastoma metastatic to the bone marrow. Arch Pathol Lab Med. 2015 Apr;139(4):543-6. PubMed PMID: 25822764
• Siegele B, Roberts J, Black JO, Rudzinski E, Vargas SO, Galambos C. DUX4 Immunohistochemistry is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor. Am J Surg Pathol. 2016 Nov 22. [Epub ahead of print] PubMed PMID: 27879517
• Mohan N, Black JO, Schwartz MR, Zhai QJ. Invasive ductal carcinoma with in situ pattern: how to avoid this diagnostic pitfall?. Am J Transl Res. 2016 Aug 15;8(8):3337-41. PubMed PMID: 27648124
• Black JO, Coffin CM, Parham DM, Hawkins DS, Speights RA, Spunt SL. Opportunities for Improvement in Pathology Reporting of Childhood Nonrhabdomyosarcoma Soft Tissue Sarcomas: ?A Report From Children's Oncology Group (COG) Study ARST0332. Am J Clin Pathol. 2016 Sep;146(3):328-38. PubMed PMID: 27510717
• Black JO. Xeroderma Pigmentosum. Head Neck Pathol. 2016 Jun;10(2):139-44. PubMed PMID: 26975629
• Winters AC, Black JO, Cost CR. Metastatic angiosarcoma arising in malignant peripheral nerve sheath tumor in a young patient with neurofibromatosis type 1. Pediatr Blood Cancer. 2017 Dec;64(12). PubMed PMID: 28548697
• Ferrari A, Chi YY, De Salvo GL, Orbach D, Brennan B, Randall RL, McCarville MB, Black JO, Alaggio R, Hawkins DS, Bisogno G, Spunt SL. Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group. Eur J Cancer. 2017 Jun;78:1-6. PubMed PMID: 28391003
• Deeney S, Stewart C, Treece AL, Black JO, Lovell MA, Garrington T, Karrer F, Bruny J. Diagnostic utility of core needle biopsy versus open wedge biopsy for pediatric intraabdominal solid tumors: Results of a prospective clinical study. J Pediatr Surg. 2017 Dec;52(12):2042-2046. PubMed PMID: 28943139
• Siegele B, Roberts J, Black JO, Rudzinski E, Vargas SO, Galambos C. DUX4 Immunohistochemistry Is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor. Am J Surg Pathol. 2017 Mar;41(3):423-429. PubMed PMID: 27879517
• Carrasco A Jr, Caldwell BT, Cost CR, Greffe BS, Garrington TP, Bruny JL, Black JO, Cost NG. Reliability of intraoperative frozen section for the diagnosis of renal tumors suspicious for malignancy in children and adolescents. Pediatr Blood Cancer. 2017 Aug;64(8). PubMed PMID: 28097784
• Davis JL, Lockwood CM, Stohr B, Boecking C, Al-Ibraheemi A, DuBois SG, Vargas SO, Black JO, Cox MC, Luquette M, Turpin B, Szabo S, Laetsch TW, Albert CM, Parham DM, Hawkins DS, Rudzinski ER. Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors. Am J Surg Pathol. 2018 Dec 24. [Epub ahead of print] PubMed PMID: 30585824
• Tetreault A, Ramalingam W, Black J, Miller NH, Donaldson N. Osteosarcoma in an Adolescent with Kniest Dysplasia: A Case Report. JBJS Case Connect. 2018 Oct-Dec;8(4):e78. PubMed PMID: 30303846
• Gilani A, Black JO, Weinman JP, Galambos C. Sudden Death Due to Complete Airway Obstruction by Bronchial Casts. Am J Respir Crit Care Med. 2018 Sep 25. [Epub ahead of print] PubMed PMID: 30252500
• Laetsch TW, Roy A, Xu L, Black JO, Coffin CM, Chi YY, Tian J, Spunt SL, Hawkins DS, Bridge JA, Parsons DW, Skapek SX. Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group. Clin Cancer Res. 2018 Aug 15;24(16):3888-3897. PubMed PMID: 29691299
• Rudzinski ER, Lockwood CM, Stohr BA, Vargas SO, Sheridan R, Black JO, Rajaram V, Laetsch TW, Davis JL. Pan-Trk Immunohistochemistry Identifies NTRK Rearrangements in Pediatric Mesenchymal Tumors. Am J Surg Pathol. 2018 Jul;42(7):927-935. PubMed PMID: 29683818
• Spunt SL, Million L, Chi YY, Anderson J, Tian J, Hibbitts E, Coffin C, McCarville MB, Randall RL, Parham DM, Black JO, Kao SC, Hayes-Jordan A, Wolden S, Laurie F, Speights R, Kawashima E, Skapek SX, Meyer W, Pappo AS, Hawkins DS. A risk-based treatment strategy for non-rhabdomyosarcoma soft-tissue sarcomas in patients younger than 30 years (ARST0332): a Children's Oncology Group prospective study. Lancet Oncol. 2020 Jan;21(1):145-161. PubMed PMID: 31786124
• Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY. A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med. 2019 Jun 3;216(6):1255-1267. PubMed PMID: 31040184
• Gilani A, Black JO, Weinman JP, Galambos C. Sudden Death due to Complete Airway Obstruction by Bronchial Casts. Am J Respir Crit Care Med. 2019 Feb 1;199(3):380. PubMed PMID: 30252500
• Davis JL, Lockwood CM, Stohr B, Boecking C, Al-Ibraheemi A, DuBois SG, Vargas SO, Black JO, Cox MC, Luquette M, Turpin B, Szabo S, Laetsch TW, Albert CM, Parham DM, Hawkins DS, Rudzinski ER. Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors. Am J Surg Pathol. 2019 Apr;43(4):435-445. PubMed PMID: 30585824
• Black JO, Folpe A. Lipoblastoma. In WHO Classification of Tumours of Soft Tissue and Bone. Fifth Edition, In Press. 2019
• Weiss AR, Chen YL, Scharschmidt TJ, Chi YY, Tian J, Black JO, Davis JL, Fanburg-Smith JC, Zambrano E, Anderson J, Arens R, Binitie O, Choy E, Davis JW, Hayes-Jordan A, Kao SC, Kayton ML, Kessel S, Lim R, Meyer WH, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Schlapkohl M, Shulkin BL, Smith EA, Sorger JI, Terezakis S, Hawkins DS, Spunt SL, Wang D. Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial. Lancet Oncol. 2020 Aug;21(8):1110-1122. PubMed PMID: 32702309
• Black JO, Folpe A. Lipoblastoma. In WHO Classification of Tumours of Soft Tissue and Bone. Fifth ed., Lyon, France, IARC Press; 2020.
• Hawkins D, Black JO, Orbach D, Scharschmidt, Scheer M, Terezakis S ,Venkatramani R, Weiss AR. Chapter 32: The Nonrhabdomyosarcoma Soft Tissue Sarcoma. In: Principles and Practice of Pediatric Oncology. 8th Edition, 2020.
• Venkatramani R, Xue W, Randall RL, Wolden S, Anderson J, Lopez-Terrada D, Black J, Kao SC, Shulkin B, Ostrenga A, Pappo A, Spunt SL. Synovial Sarcoma in Children, Adolescents, and Young Adults: A Report From the Children's Oncology Group ARST0332 Study. J Clin Oncol. 2021 Dec 10;39(35):3927-3937. PubMed PMID: 34623899
• Buehler PW, Swindle D, Pak DI, Ferguson SK, Majka SM, Karoor V, Moldovan R, Sintas C, Black J, Gentinetta T, Buzzi RM, Vallelian F, Wassmer A, Edler M, Bain J, Schu D, Hassell K, Nuss R, Schaer DJ, Irwin DC. Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. Free Radic Biol Med. 2021 Nov 1;175:95-107. PubMed PMID: 34478834
• Friedlander JA, Fleischer DM, Black JO, Levy M, Rothenberg ME, Smith C, Nguyen N, Pan Z, Furuta GT. Unsedated transnasal esophagoscopy with virtual reality distraction enables earlier monitoring of dietary therapy in eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2021 Sep;9(9):3494-3496. PubMed PMID: 34224927
• Million L, Hayes-Jordan A, Chi YY, Donaldson SS, Wolden S, Morris C, Terezakis S, Laurie F, Morano K, Fitzgerald TJ, Yock TI, Rodeberg DA, Anderson JR, Speights RA, Black JO, Coffin C, McCarville MB, Kao SC, Hawkins DS, Spunt SL, Randall RL. Local Control For High-Grade Nonrhabdomyosarcoma Soft Tissue Sarcoma Assigned to Radiation Therapy on ARST0332: A Report From the Childrens Oncology Group. Int J Radiat Oncol Biol Phys. 2021 Jul 1;110(3):821-830. PubMed PMID: 33548339
• Harding E, Hill LR, Black JO, Annam A, Wright CJ. Term Neonate with Progressive Respiratory Distress. J Pediatr. 2023 Dec;263:113704. PubMed PMID: 37640231
• Weiss AR, Chen YL, Scharschmidt TJ, Xue W, Gao Z, Black JO, Choy E, Davis JL, Fanburg-Smith JC, Kao SC, Kayton ML, Kessel S, Lim R, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Shulkin BL, Terezakis S, Venkatramani R, Zambrano E, Wang D, Hawkins DS, Spunt SL. Outcomes After Preoperative Chemoradiation With or Without Pazopanib in Non-Rhabdomyosarcoma Soft Tissue Sarcoma: A Report From Children's Oncology Group and NRG Oncology. J Clin Oncol. 2023 Nov 1;41(31):4842-4848. PubMed PMID: 37523624
• Black JO, Al-Ibraheemi A, Arnold MA, Coffin CM, Davis JL, Parham DM, Rudzinski ER, Shenoy A, Surrey LF, Tan SY, Spunt SL. The Pathologic Diagnosis of Pediatric Soft Tissue Tumors in the Era of Molecular Medicine: The Sarcoma Pediatric Pathology Research Interest Group Perspective. Arch Pathol Lab Med. 2024 Jan 1;148(1):107-116. PubMed PMID: 37196343
• Boster JM, Dominguez SR, Messacar K, Adams M, Weinberg A, Black JO, Feldman AG. Acute Liver Failure in a Child With Adenovirus Detected by PCR in the Explanted Liver. Pediatrics. 2023 Feb 1;151(2). PubMed PMID: 36691756
• Benson TM, Markey GE, Hammer JA, Simerly L, Dzieciatkowska M, Jordan KR, Capocelli KE, Scullion KM, Crowe L, Ryan S, Black JO, Crue T, Andrews R, Burger C, McNamee EN, Furuta GT, Menard-Katcher C, Masterson JC. CSF1-dependent macrophage support matrisome and epithelial stress-induced keratin remodeling in Eosinophilic esophagitis. Mucosal Immunol. 2024 Sep 27. [Epub ahead of print] PubMed PMID: 39343055
• Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris M, Adams DL, Hayashi M. Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells. bioRxiv. 2024 Jun 20. PubMed PMID: 38293103

Professional Memberships

• Society for Pediatric Pathology, Member
• United States and Canadian Academy of Pathologists, Abstract Committee
• Children's Oncology Group, STS Committee, Membership Committee, Pathology Steering Committee

Practice Locations

• University of Colorado Hospital
• Children's Hospital Colorado

Specialty Information

• Anatomic and Clinical, Board Certification (2007, 2017)
• Pediatric Pathology, Board Certification (2009, 2017)

• Cancers - Pediatric Cancer
• Cancers
• Cancers - Sarcoma