Laura Pyle, PhD

Chan CL, Pyle L, Newnes L, Nadeau KJ, Zeitler PS, Kelsey MM. Continuous Glucose Monitoring and its Relationship to Hemoglobin A1c and Oral Glucose Tolerance Testing in Obese and Prediabetic Youth. J Clin Endocrinol Metab. 2014 Dec 22;:jc20143612. [Epub ahead of print] PubMed PMID: 25532041

White NH, Pyle L, Willi SM, Pham T, Chernausek SD, Goland R, Hale DE, Haymond MW, Nadeau KJ, Narasimham S. 2013. Safety and tolerability of the treatment of youth-onset type 2 diabetes: the TODAY experience. Diabetes Care, 36: 1765-1771.

Bjornstad P, Maahs DM, Wadwa RP, Pyle L, Rewers M, Eckel RH, Snell-Bergeon JK. Plasma triglycerides predict incident albuminuria and progression of coronary artery calcification in adults with type 1 diabetes: The Coronary Artery Calcification in Type 1 Diabetes Study. J Clin Lipidol. 2014 Nov-Dec;8(6):576-83. PubMed PMID: 25499940

Copeland KC, Higgins J, El ghormli L, Delahanty L, Grey M, Kriska AM, Lipman TH, Pyle L, Shepherd J, Hirst K. 2013. Treatment effects on measures of body composition in the TODAY clinical trial. Diabetes Care, 36: 1742-1748.

Bjornstad P, Cree-Green M, Baumgartner A, Maahs DM, Cherney DZ, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Renal function is associated with peak exercise capacity in adolescents with type 1 diabetes. Diabetes Care. 2015 Jan;38(1):126-31. PubMed PMID: 25414156

Stewart CL, Mulligan J, Grudic GZ, Pyle L, Moulton SL. A noninvasive computational method for fluid resuscitation monitoring in pediatric burns: a preliminary report. J Burn Care Res. 2015 Jan-Feb;36(1):145-50. PubMed PMID: 25383980

Cree-Green M, Newcomer BR, Brown MS, Baumgartner AD, Bergman B, Drew B, Regensteiner JG, Pyle L, Reusch JE, Nadeau KJ. Delayed skeletal muscle mitochondrial ADP recovery in youth with type 1 diabetes relates to muscle insulin resistance. Diabetes. 2014 Aug 25. [Epub ahead of print] PubMed PMID: 25157095

Lynch J, El ghormli L, Gidding SS, Fisher L, Laffel L, Libman I, Pyle L, Tamborlane WV, Tollefsen S, Weinstock R, Zeitler P. 2013. Rapid rise in hypertension and nephropathy in youth with type 2 diabetes: the TODAY clinical trial. Diabetes Care, 36: 1735-1741.

Bjornstad P, Maahs DM, Cherney DZ, Cree-Green M, West A, Pyle L, Nadeau KJ. Insulin sensitivity is an important determinant of renal health in adolescents with type 2 diabetes. Diabetes Care. 2014 Nov;37(11):3033-9. PubMed PMID: 25071077

Maahs DM, Bushman L, Kerr B, Ellis SL, Pyle L, McFann K, Bouffard A, Bishop FK, Nguyen N, Anderson PL. A practical method to measure GFR in people with type 1 diabetes. J Diabetes Complications. 2014 Sep-Oct;28(5):667-73. PubMed PMID: 25027389

Stewart CL, Mulligan J, Grudic GZ, Pyle L, Moulton SL. 2014. A non-invasive computational method for fluid resuscitation monitoring in pediatric burns: a preliminary report. Accepted for presentation at the 46th Annual Meeting of the American Burn Association.

Lindquist KA, Chow K, West A, Pyle L, Isbell TS, DuBois JA, Cree-Green M, Nadeau KM. 2014. The Statstrip® glucose monitor is suitable for use during hyperinsulinemic euglycemic clamps in a pediatric population. Accepted for presentation at the 7th International Conference on Advanced Technologies and Treatments for Diabetes.

Arslanian SA, Pyle L, White NH, Bacha F, Caprio S, Haymond MH, Levitsky L, Goland RS, Willi SM. 2013. Racial disparity in maintenance of glycemic control in the TODAY trial: does insulin sensitivity, ß-cell function, or both play a role? Poster presentation at the 2013 meeting of the American Diabetes Association.

Bjornstad P, Maahs DM, Rivard CJ, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol. 2014 Oct;51(5):783-91. PubMed PMID: 24929955

Bjornstad P, McQueen RB, Snell-Bergeon JK, Cherney D, Pyle L, Perkins B, Rewers M, Maahs DM. Fasting blood glucose--a missing variable for GFR-estimation in type 1 diabetes?. PLoS One. 2014;9(4):e96264. PubMed PMID: 24781861

Lindquist KA, Chow K, West A, Pyle L, Isbell TS, Cree-Green M, Nadeau KJ. The StatStrip glucose monitor is suitable for use during hyperinsulinemic euglycemic clamps in a pediatric population. Diabetes Technol Ther. 2014 May;16(5):298-302. PubMed PMID: 24471560

Maahs DM, Chase HP, Westfall E, Slover R, Huang S, Shin JJ, Kaufman FR, Pyle L, Snell-Bergeon JK. The effects of lowering nighttime and breakfast glucose levels with sensor-augmented pump therapy on hemoglobin A1c levels in type 1 diabetes. Diabetes Technol Ther. 2014 May;16(5):284-91. PubMed PMID: 24450776

Chan C, Pyle L, Kelsey M, Newnes L, Zeitler P, Nadeau K. In press. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternative markers of glycemia – 1,5-andhydroglucitol, fructosamine, and glycated albumin. Pediatric Diabetes.

Bjornstad P, Pyle L, Nguyen N, Snell-Bergeon JK, Bishop FK, Wadwa RP, Maahs DM. In press. Achieving International Society for Pediatric and Adolescent Diabetes and American Diabetes Association clinical guidelines offers cardiorenal protection for youth with type 1 diabetes. Pediatric Diabetes.

Kelsey MM, Geffner ME, Guandalini C, Pyle L, Tamborlane WV, Zeitler PS, White NH. In press. Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY study. Pediatric Diabetes.

Stewart CL, Metzger RR, Pyle L, Darmofal J, Scaife E, Moulton SL. In press. Helicopter vs. ground emergency medical services for the transportation of traumatically injured children. Journal of Pediatric Surgery.

Katz LK, Gidding SS, Bacha F, Hirst K, McKay S, Pyle L, Lima JAC. In press. Alterations in left ventricular, left atrial, and right ventricular structure and function to cardiovascular risk factors in adolescents with type 2 diabetes: the TODAY clinical trial. Pediatric Diabetes.

Truong U, Baumgartner A, Coe G, Pyle L, Patel S, Nadeau KJ. Increased aortic stiffness in adolescents with type 1 diabetes by cardiac magnetic resonance. Poster presentation at Society for Cardiovascular Magnetic Resonance 2015.

Cree-Green M, Gupta A, Coe G, Baumgartner A, Pyle L, Reusch JE, Brown M, Newcomer BR, Nadeau KJ. Insulin resistance is related to decreased mitochondrial function and elevated free fatty acids but not intramyocellular lipid in adolescents with type 2 diabetes. Oral presentation at Endocrine Society 2015.

Ohman R, Cree-Green M, Pyle L, Bessesen DH, Sharp T, Kelsey MM, Pereira RI, Nadeau KJ. Ethnic and sex differences in adiponectin across the lifespan. Poster presentation at Endocrine Society 2015.

Pivarunas B, Nadeau KJ, Van Pelt RE, Hilkin A, Chosich J, Pyle L, Zeitler P, Santoro N, Kelsey M. Evidence for gonadal dysfunction in obese girls early in puberty. Poster presentation at Endocrine Society 2015.

Maahs D, Messer L, Pyle L, Wadwa P, Westfall E, DeSalvo D, Clinton P, Block J, Ly T, Buckingham B. Effect of acetaminophen on CGM glucose in an out-patient setting. Poster presentation at the 8th International Conference on Advanced Technologies & Treatments for Diabetes.

Stewart C, Acker S, Pyle L, Cadnapaphornchai M, Kulungowski A, Karrer F, Bruny J. Features associated with peritoneal dialysis catheter complications. Poster presentation at the American Pediatric Surgical Association 2015 Annual Meeting.

Bjornstad P, Cree-Green M, Baumgartner A, Maahs DM, Cherney DZ, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Renal health is an important determinant of cardiac and exercise function in adolescents with type 1 diabetes. Poster presentation at Kidney Week 2014.

Chan CL, Pyle L, Retamal-Munoz C, Morehead R, Zemanick ET, Sagel S, Klingensmith GJ. Lung function decline and glycemic patterns in youth with cystic fibrosis characterized by a standardized approach to continuous glucose monitoring analysis. Poster presentation at the 2014 North American Cystic Fibrosis Conference.

Kelsey M, Chan C, Pyle L, Adams J, Hilkin A, Newnes L, Cree-Green M, Nadeau K. Prediabetes presents late in puberty in obese youth. Poster presentation at the 2014 Annual Meeting of The Obesity Society.

Curtis D, Cho A, Pyle L, Weinberg A. Antibody and cellular immune responses to 2011-2012 seasonal inactivated influenza vaccine in HIV-infected and uninfected children and young adults. Poster presentation at the 2014 IDWeek.

Bjornstad P, Pyle L, Nguyen N, Snell-Bergeon JK, Maahs DM, Wadwa RP. Does achievement of International Society for Pediatric and Adolescent Diabetes Clinical Guidelines offer cardiorenal protection for youth with Type 1 diabetes? Oral presentation at the 2014 Annual Conference of the International Society for Pediatric and Adolescent Diabetes.

Stewart CL, Pyle L, Smith DS, Bensard DD, Moulton SL. Mapping pediatric traumas to target prevention, education, and outreach. Oral presentation at the 2014 American Academy of Pediatrics National Conference and Exhibition.

Stewart C, Metzger R, Pyle L, Darmofal J, Scaife E, Moulton SL. Helicopter versus ground emergency medical services for transportation of traumatically injured children. Oral presentation at the 2014 Western Pediatric Trauma Conference.

Bacha F, Gidding SS, Pyle L, Katz LL, Kriska A, Nadeau KJ. Relationship of echocardiogram to cardiorespiratory fitness and body composition in youth with type 2 diabetes. Oral presentation at the 2014 meeting of the American Diabetes Association.

Snell-Bergeon JK, Pyle L, Shin JJ, Huang S, Kaufman FR, Maahs DM. The ratio of continuous glucose monitor glucose and glycated hemoglobin: the STAR3 study. Poster presentation at the 2014 meeting of the American Diabetes Association.

Chan CL, Pyle L, Nadeau KJ, Newnes L, Zeitler PS, Kelsey MM. The relationships among fructosamine, glycated albumin, and 1,5 anhydroglucitol with A1c, 2hr plasma glucose, and continuous glucose monitoring in obese adolescents. Poster presentation at the 2014 meeting of the American Diabetes Association.

Stewart CL, Mulligan J, Grudic GZ, Pyle L, Moulton SL. 2014. A non-invasive computational method for fluid resuscitation monitoring in pediatric burns: a preliminary report. Oral presentation at the 46th Annual Meeting of the American Burn Association.

Lindquist KA, Chow K, West A, Pyle L, Isbell TS, DuBois JA, Cree-Green M, Nadeau KM. 2014. The Statstrip® glucose monitor is suitable for use during hyperinsulinemic euglycemic clamps in a pediatric population. Oral presentation at the 7th International Conference on Advanced Technologies and Treatments for Diabetes.

Stewart CL, Acker SN, Pyle LL, Kulungowski A, Cadnapaphornchai M, Bruny JL, Karrer F. Factors associated with peritoneal dialysis catheter complications in children. J Pediatr Surg. 2015 Oct 21. [Epub ahead of print] PubMed PMID: 26572851

Maahs DM, DeSalvo D, Pyle L, Ly T, Messer L, Clinton P, Westfall E, Wadwa RP, Buckingham B. Effect of Acetaminophen on CGM Glucose in an Outpatient Setting. Diabetes Care. 2015 Oct;38(10):e158-9. PubMed PMID: 26269199

Bjornstad P, Eckel RH, Pyle L, Rewers M, Maahs DM, Snell-Bergeon JK. Relation of Combined Non-High-Density Lipoprotein Cholesterol and Apolipoprotein B With Atherosclerosis in Adults With Type 1 Diabetes Mellitus. Am J Cardiol. 2015 Oct 1;116(7):1057-62. PubMed PMID: 26251001

Cree-Green M, Maahs DM, Ferland A, Hokanson JE, Wang H, Pyle L, Kinney GL, King M, Eckel RH, Nadeau KJ. Lipoprotein subfraction cholesterol distribution is more atherogenic in insulin resistant adolescents with type 1 diabetes. Pediatr Diabetes. 2015 Jun 17. [Epub ahead of print] PubMed PMID: 26080650

Bjornstad P, Cherney DZ, Snell-Bergeon JK, Pyle L, Rewers M, Johnson RJ, Maahs DM. Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with Type 1 diabetes. Nephrol Dial Transplant. 2015 Oct;30(10):1706-11. PubMed PMID: 26050268

Cree-Green M, Newcomer BR, Coe G, Newnes L, Baumgartner A, Brown MS, Pyle L, Reusch JE, Nadeau KJ. Peripheral insulin resistance in obese girls with hyperandrogenism is related to oxidative phosphorylation and elevated serum free fatty acids. Am J Physiol Endocrinol Metab. 2015 May 1;308(9):E726-33. PubMed PMID: 25714677

Kelsey MM, Geffner ME, Guandalini C, Pyle L, Tamborlane WV, Zeitler PS, White NH. Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY study. Pediatr Diabetes. 2015 Feb 17. [Epub ahead of print] PubMed PMID: 25690268

Chan CL, Pyle L, Kelsey M, Newnes L, Zeitler PS, Nadeau KJ. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin. Pediatr Diabetes. 2015 Feb 5. [Epub ahead of print] PubMed PMID: 25652226

Stewart CL, Metzger RR, Pyle L, Darmofal J, Scaife E, Moulton SL. Helicopter versus ground emergency medical services for the transportation of traumatically injured children. J Pediatr Surg. 2015 Feb;50(2):347-52. PubMed PMID: 25638635

Bjornstad P, Pyle L, Nguyen N, Snell-Bergeon JK, Bishop FK, Wadwa RP, Maahs DM. Achieving International Society for Pediatric and Adolescent Diabetes and American Diabetes Association clinical guidelines offers cardiorenal protection for youth with type 1 diabetes. Pediatr Diabetes. 2015 Feb;16(1):22-30. PubMed PMID: 25604668

Bjornstad P, Nguyen N, Reinick C, Maahs DM, Bishop FK, Clements SA, Snell-Bergeon JK, Lieberman R, Pyle L, Daniels SR, Paul Wadwa R. Association of apolipoprotein B, LDL-C and vascular stiffness in adolescents with type 1 diabetes. Acta Diabetol. 2015 Jun;52(3):611-9. PubMed PMID: 25539881

Chan CL, Pyle L, Newnes L, Nadeau KJ, Zeitler PS, Kelsey MM. Continuous glucose monitoring and its relationship to hemoglobin A1c and oral glucose tolerance testing in obese and prediabetic youth. J Clin Endocrinol Metab. 2015 Mar;100(3):902-10. PubMed PMID: 25532041

Bjornstad P, Cree-Green M, Baumgartner A, Maahs DM, Cherney DZ, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Renal function is associated with peak exercise capacity in adolescents with type 1 diabetes. Diabetes Care. 2015 Jan;38(1):126-31. PubMed PMID: 25414156

Stewart CL, Mulligan J, Grudic GZ, Pyle L, Moulton SL. A noninvasive computational method for fluid resuscitation monitoring in pediatric burns: a preliminary report. J Burn Care Res. 2015 Jan-Feb;36(1):145-50. PubMed PMID: 25383980

Cree-Green M, Newcomer BR, Brown MS, Baumgartner AD, Bergman B, Drew B, Regensteiner JG, Pyle L, Reusch JE, Nadeau KJ. Delayed skeletal muscle mitochondrial ADP recovery in youth with type 1 diabetes relates to muscle insulin resistance. Diabetes. 2015 Feb;64(2):383-92. PubMed PMID: 25157095

Levitt Katz L, Gidding SS, Bacha F, Hirst K, McKay S, Pyle L, Lima JA. Alterations in left ventricular, left atrial, and right ventricular structure and function to cardiovascular risk factors in adolescents with type 2 diabetes participating in the TODAY clinical trial. Pediatr Diabetes. 2015 Feb;16(1):39-47. PubMed PMID: 24450390

Klingensmith GK, Pyle L, Nadeau KJ, Barbour LA, Goland RS, Willi SM, Linder B, White NH. In press. Pregnancy outcomes in youth with type 2 diabetes: the TODAY study experience. Diabetes Care.

Stewart C, Acker S, Pyle L, Cadnapaphornchai M, Kulungowski A, Karrer F, Bruny J. Features associated with peritoneal dialysis catheter complications. Poster presentation at the American Pediatric Surgical Association 2015 Annual Meeting.

Maahs D, Messer L, Pyle L, Wadwa P, Westfall E, DeSalvo D, Clinton P, Block J, Ly T, Buckingham B. Effect of acetaminophen on CGM glucose in an out-patient setting. Poster presentation at the 8th International Conference on Advanced Technologies & Treatments for Diabetes.

Pivarunas B, Nadeau KJ, Van Pelt RE, Hilkin A, Chosich J, Pyle L, Zeitler P, Santoro N, Kelsey M. Evidence for gonadal dysfunction in obese girls early in puberty. Poster presentation at Endocrine Society 2015.

Ohman R, Cree-Green M, Pyle L, Bessesen DH, Sharp T, Kelsey MM, Pereira RI, Nadeau KJ. Ethnic and sex differences in adiponectin across the lifespan. Poster presentation at Endocrine Society 2015.

Cree-Green M, Gupta A, Coe G, Baumgartner A, Pyle L, Reusch JE, Brown M, Newcomer BR, Nadeau KJ. Insulin resistance is related to decreased mitochondrial function and elevated free fatty acids but not intramyocellular lipid in adolescents with type 2 diabetes. Oral presentation at Endocrine Society 2015.

Truong U, Baumgartner A, Coe G, Pyle L, Patel S, Nadeau KJ. Increased aortic stiffness in adolescents with type 1 diabetes by cardiac magnetic resonance. Poster presentation at Society for Cardiovascular Magnetic Resonance 2015.

Wadwa, RP, DeSavlo DJ, Westfall E, Pyle L, Messer LH, Ly TT, Maahs DM, Buckingham BA. Hyaluronidase use with insulin pumps does not change insulin use or glucose control in type 1 diabetes. Poster presentation at the 2015 meeting of the American Diabetes Association.

Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Oral presentation at the 2015 meeting of the American Diabetes Association.

Ohman R, Cree-Green M, Sharp T, Pyle L, Pereira R, Kelsey MM, Nadeau KJ. Ethnic differences is insulin resistance and ß-cell function in peripubertal children. Poster presentation at the 2015 meeting of Pediatric Academic Societies.

Triolo TM, Maahs DM, Cheng P, Pyle L, Buckingham BA, Slover R, Chase HP. Effects of sensor augmented pump use on HbA1c and C-peptide in the first year of type 1 diabetes. Oral presentation at the 2015 meeting of the American Diabetes Association.

Clover G, Pyle L, Lloyd L. Medical care and runner characteristics at a 161-km high altitude ultra-endurance run in Colorado, 2014. Oral presentation at the 2015 Medicine and Science in Ultra-endurance Sports Conference.

Spruiell M, Wylie E, Roberts J, Pyle L, Parker S, Heare T. Is it worth the effort? The outcomes of a multidisciplinary clinical care guideline for acute pediatric musculoskeletal infections. Poster presentation at the 2015 meeting of the Pediatric Orthopedic Society of North America.

Spruiell M, Wylie E, Roberts J, Pyle L, Parker S, Heare T. Treatment guidelines for acute pediatric musculoskeletal infections: worth the effort? Oral presentation at the Western Orthopaedic Association’s 2015 Annual Meeting.

Maddux AB, Overdier KH, Hiller TD, Pyle L, Douglas IS. Innate immune suppression and organ function recovery in severe sepsis. Poster presentation at the 2015 meeting of the Pediatric Academic Societies.

Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK. Factors involved in predicting time to type 1 diabetes in antibody positive TrialNet subjects. Poster presentation at the 2015 meeting of the American Diabetes Association.

Bjornstad P, Snell-Bergeon JK, Cherney D, Pyle L, Johnson RJ, Rewers M, Maahs DM. Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with type 1 diabetes. Poster presentation at the 2015 meeting of the American Diabetes Association.

DeSalvo DJ, Ly TT, Maahs DM, Messer LH, Pyle L, Wadwa P, Westfall E, Hanes S, Buckingham BA. Duration of infusion set survival with hyaluronidase injected at insulin pump infusion site. Poster presentation at the 2015 meeting of the American Diabetes Association.

Bjornstad P, Roncal C, Pyle L, Lanaspa MG, Snell-Bergeon JK, Johnson RJ, Wadwa RP, Maahs DM. Renal hyperfiltration in adolescents with T1D is associated with elevated urine uric acid and fractionated uric acid. Poster presentation at the 2015 meeting of the American Diabetes Association.

Murphy Zane MS, Terhune EB, Smith N, Pyle L. Reliability of the anterior humeral line and the Gartland/Wilkins classification for supracondylar humerus fractures. Poster presentation at the 2015 meeting of the Pediatric Orthopedic Society of North America.

Llunggren P, Johansson P, Pyle L, Maahs D, Sippl R, Ludvigsson J, Wadwa P, Snell-Bergeon J. Accelerated decline in brachial distensibility in women with type 1 diabetes: a cross-sectional study. Poster presentation at the 2015 meeting of the European Association for the Study of Diabetes.

Smith D, Pyle L, Stewart C, Bensard DD, Moulton SL, Reiter S. Mapping injury data to inform targeted approaches to prevention. Oral presentation at the 2015 Safe States Alliance Annual Meeting.

Smith D, Pyle L, Stewart C, Bensard DD, Moulton SL, Reiter S. Mapping pediatric injuries to inform target approaches to prevention. Oral presentation at 2015 Public Health in the Rockies Conference.

Chan CL, Pyle L, Vigers T, Zemanick ET, Zeitler PS, Sagel SD, Nadeau K. Continuous glucose monitoring reveals glucose abnormalities in CF youth despite normal oral glucose tolerance testing. Oral presentation at the 2015 North American Cystic Fibrosis Conference.

Pyle L, Bergman B, Nadeau KJ, Cree-Green M. Measuring changes in glucose rate of appearance in patients with diabetes. Oral presentation at the 2015 meeting of the International Society for Pediatric and Adolescent Diabetes.

Klingensmith GK, Pyle L, Nadeau KJ, Barbour LA, Goland RS, Willi SM, Linder B, White NH. Pregnancy outcomes in youth with type 2 diabetes: the TODAY study experience. Oral presentation at the 2015 International Diabetes Federation-American Diabetes Association Symposium at the IDF World Diabetes Congress Symposium.

Parker SK, Spruiell MD, Wylie E, Pyle L, Pearce K, Stewart J, Heizer H, Donaldson D, Child J, Scott H, Reese J, Ballard M, Erickson M, Anderson CJ, Roberts JL, Heare T. A clinical care guideline for pediatric acute musculoskeletal infections improves outcomes. Poster presentation at 2015 ID Week.

Bjornstad P, Pyle L, Snell-Bergeon J, Moulton KS, Nadeau K. Urinary matrix metalloproteinase activities are associated with renal hyperfiltration in adolescents with type 2 diabetes. Poster presentation at Kidney Week 2015.

Kelsey MM, Jin D, Hilkin A, Pyle L, Van Pelt R, Nadeau KJ, Zeitler PE. Leptin is a potential mediator of physiologic insulin resistance in puberty. Oral presentation at the 13th Annual World Congress on Insulin Resistance, Diabetes, and Cardiovascular Disease.

Simon SL, Cree-Green M, Pyle L, Coe G, Halbower A. Sleep and insulin resistance in adolescent girls with obesity. Oral presentation at the 2015 Pediatric Sleep Medicine Meeting.

Sewell RL, Scherzinger A, Pyle L, Cree-Green M, Nadeau KJ. Non-alcoholic fatty liver disease in obese adolescent girls is associated with insulin resistance and predictors of cardiometabolic disease. Oral presentation at the 2016 Western Regional Meeting of the American Federation for Medical Research.

Forlenza GP, Pyle L, Maahs DM, Dunn TC. Ambulatory Glucose Profile characterization of Juvenile Diabetes Research Foundation-Continuous Glucose Monitoring Trial data. Poster presentation at the 2016 International Conference on Advanced Technologies and Treatments for Diabetes.

Pyle L, Bergman BC, Nadeau KJ, Cree-Green M. Modeling changes in glucose and glycerol rate of appearance when true basal rates of appearance cannot readily be determined. American Journal of Physiology – Endocrinology and Metabolism.

Forlenza GP, Pyle L, Maahs DM, Dunn TC. Ambulatory Glucose Profile analysis of the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring dataset – applications to the pediatric diabetes population. Pediatric Diabetes (in press).

Bjornstad P, Johnson R, Snell-Bergeon J, Pyle L, Davis A, Foster N, Cherney D, Maahs D. Albuminuria is associated with greater copeptin concentrations in men with type 1 diabetes: a brief report from The T1D Exchange Biobank. Journal of Diabetes and its Complications (in press).

Milan M, Jhajj S, Stewart C, Pyle L, Moulton S. Helmet use and injury severity among pediatric skiers and snowboarders. Journal of Pediatric Surgery (in press).

Cree-Green M, Gupta A, Coe GV, Baumgartner AD, Pyle L, Reusch JEB, Brown MS, Newcomer BR Nadeau KJ. Insulin resistance is related to mitochondrial dysfunction and elevated free fatty acids but not intramyocellular lipid in adolescents with type 2 diabetes. Journal of Diabetes and its Complications (in press).

Cree-Green M, Gupta A, Coe GV, Baumgartner AD, Pyle L, Reusch JE, Brown MS, Newcomer BR, Nadeau KJ. Insulin resistance in type 2 diabetes youth relates to serum free fatty acids and muscle mitochondrial dysfunction. J Diabetes Complications. 2016 Oct 17. [Epub ahead of print] PubMed PMID: 27839922

Cree-Green M, Bergman BC, Coe GV, Newnes L, Baumgartner AD, Bacon S, Sherzinger A, Pyle L, Nadeau KJ. Hepatic Steatosis is Common in Adolescents with Obesity and PCOS and Relates to De Novo Lipogenesis but not Insulin Resistance. Obesity (Silver Spring). 2016 Nov;24(11):2399-2406. PubMed PMID: 27804265

Mullin BC, Pyle L, Haraden D, Riederer J, Brim N, Kaplan D, Novins D. A Preliminary Multimethod Comparison of Sleep Among Adolescents With and Without Generalized Anxiety Disorder. J Clin Child Adolesc Psychol. 2016 Oct 13;:1-13. [Epub ahead of print] PubMed PMID: 27736237

Baldelli L, Flitter B, Pyle L, Maahs DM, Klingensmith G, Slover R, Alonso GT. A survey of youth with new onset type 1 diabetes: Opportunities to reduce diabetic ketoacidosis. Pediatr Diabetes. 2016 Oct 11. [Epub ahead of print] PubMed PMID: 27726268

Sewell RL, Scherzinger A, Pyle L, Cree-Green M, Nadeau KJ. Non-alcoholic fatty liver disease in obese adolescent girls is associated with insulin resistance and predictors of cardiometabolic disease. Oral presentation, Western Regional Meeting of the American Federation for Medical Research, 2016.

Forlenza GP, Pyle L, Maahs DM, Dunn TC. Ambulatory Glucose Profile characterization of Juvenile Diabetes Research Foundation-Continuous Glucose Monitoring Trial data. Poster presentation, International Conference on Advanced Technologies and Treatments for Diabetes, 2016.

Baldelli L, Flitter B, Pyle L, Maahs DM, Klingensmith G, Slover R, Alonso GT. A survey of youth diagnosed with type 1 diabetes (T1D): identifying opportunities to reduce the incidence of diabetic ketoacidosis (DKA). Oral presentation, American Diabetes Association, 2016.

Keshawarz A, Duca L, Shah V, Pyle L, Sippl RM, Snell-Bergeon JK. Menopause and cardiovascular risk in women with type 1 diabetes. Poster presentation, American Diabetes Association, 2016.

Shah VN, Pyle L, Struemph T, Sippl R, Snell-Bergeon JK. Factors affecting fracture risk in type 1 diabetes: analysis from the Coronary Artery Calcification in Type 1 Diabetes (CACTI) study. Poster presentation, American Diabetes Association, 2016.

Polsky S, Pyle L, Shah V, Snell-Bergeon JK. Challenges in managing diabetes care in older adults with type 1 diabetes. Abstract accepted for publication, American Diabetes Association, 2016.

Cree-Green M, Pyle L, Brown MS, Newcomer BR, Ringham B, Nadeau KJ, Dabelea D. Sex differences in insulin sensitivity in youth without diabetes exist, but have no relationship with muscle mitochondrial function. Poster presentation, American Diabetes Association, 2016.

Davis S, Lahlou N, Bardsley M, Temple MC, Kowal K, Pyle L, Zeitler P, Ross J. Gonadal function is associated with cardiometabolic health in pre-pubertal boys with Klinefelter syndrome. Andrology. 2016 Sep 16. [Epub ahead of print] PubMed PMID: 27637014

Ohman-Hanson R, Cree-Green M, Kelsey MM, Bessesen DH, Sharp TA, Pyle L, Pereira RI, Nadeau KJ. Ethnic and sex differences in adiponectin: from childhood to adulthood. J Clin Endocrinol Metab. 2016 Sep 7;:jc20161137. [Epub ahead of print] PubMed PMID: 27603898

Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Pediatr Diabetes. 2016 Aug 9. [Epub ahead of print] PubMed PMID: 27503277

Bjornstad P, Schmidt AM, Zhang J, Pyle L, Johnson RJ, Rewers M, Maahs DM, Snell-Bergeon JK. Advanced glycation end product receptors and diabetic kidney disease in type 1 diabetes. Moderated poster presentation, American Diabetes Association, 2016.

Bacha F, Gidding SS, Pyle L, Levitt Katz L, Kriska A, Nadeau KJ, Lima JA. Relationship of Cardiac Structure and Function to Cardiorespiratory Fitness and Lean Body Mass in Adolescents and Young Adults with Type 2 Diabetes. J Pediatr. 2016 Oct;177:159-166.e1. PubMed PMID: 27499218

Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK. Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects?. Diabetes Care. 2016 Oct;39(10):1738-44. PubMed PMID: 27456836

Bjornstad P, Pyle L, Kinney GL, Rewers M, Johnson RJ, Maahs DM, Snell-Bergeon JK. Adiponectin is associated with early diabetic kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study. J Diabetes Complications. 2016 Jun 14. [Epub ahead of print] PubMed PMID: 27368123

Karlin AW, Ly TT, Pyle L, Forlenza GP, Messer L, Wadwa RP, DeSalvo DJ, Payne SL, Hanes S, Clinton P, Maahs DM, Buckingham B. Duration of Infusion Set Survival in Lipohypertrophy Versus Nonlipohypertrophied Tissue in Patients with Type 1 Diabetes. Diabetes Technol Ther. 2016 Jul;18(7):429-35. PubMed PMID: 27227290

GT Alonso, Pyle L, Frohnert B. Change in hemoglobin A1c following new ADA targets for children. Poster presentation, American Diabetes Association, 2016.

Murphy JL, Fenn N, Pyle L, Heizer H, Hughes S, Nomura Y, Child J, Parker SK. Adverse Events in Pediatric Patients Receiving Long-term Oral and Intravenous Antibiotics. Hosp Pediatr. 2016 Jun;6(6):330-8. PubMed PMID: 27220835

Bjornstad P, Truong U, Pyle L, Dorosz JL, Cree-Green M, Baumgartner A, Coe G, Regensteiner JG, Reusch JE, Nadeau KJ. Youth with type 1 diabetes have worse strain and less pronounced sex differences in early echocardiographic markers of diabetic cardiomyopathy compared to their normoglycemic peers: A RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) Study. J Diabetes Complications. 2016 Aug;30(6):1103-10. PubMed PMID: 27133451

Ljunggren P, Maahs DM, Johansson P, Ludvigsson J, Pyle L, Sippl R, Wadwa RP, Snell-Bergeon J. Reduced brachial artery distensibility in patients with type 1 diabetes. J Diabetes Complications. 2016 Jul;30(5):893-7. PubMed PMID: 27056753

Fouts A, Pyle L, Yu L, Muller S, Fain P, Gottlieb P, Steck AK and the Type 1 Diabetes TrialNet Study Group. Autoantibody prevalence in twins and siblings at screening in the TrialNet Pathway to Prevention study. Poster presentation, American Diabetes Association, 2016.

Bjornstad P, Truong U, Dorosz JL, Cree-Green M, Baumgartner A, Coe G, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Cardiopulmonary Dysfunction and Adiponectin in Adolescents With Type 2 Diabetes. J Am Heart Assoc. 2016 Mar 18;5(3):e002804. PubMed PMID: 26994128

Nadeau KJ, Baumgartner A, Coe G, Pyle L, Cree-Green M, Regensteiner JG, Reusch JEB, Bjornstad P. Cardiopulmonary fitness is associated with arterial health in adolescents with type 1 diabetes: the EMERALD study. Moderated poster presentation, American Diabetes Association, 2016.

Kinney G, Duca L, Bjornstad P, Pyle L, Maahs D, Rewers M, Snell-Bergeon JK. Long-term glycemic control and pulmonary function in type 1 diabetes. Poster presentation, American Diabetes Association, 2016.

Kelsey MM, Jin D, Hilkin A, Pyle L, Van Pelt R, Nadeau KJ, Zeitler PE. Insulin secretion, but not sensitivity, is associated with decreased SHBG during puberty. Poster presentation, American Diabetes Association, 2016.

Milan M, Stewart C, Jhajj S, Pyle L, Moulton S. Factors that affect the injury and severity in pediatric skiers and snowboarders. Oral presentation, Western Pediatric Trauma Conference, 2016 (accepted).

Bjornstad P, Maahs DM, Duca LM, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Estimated insulin sensitivity predicts incident micro- and macrovascular complications in adults with type 1 diabetes over 6 years: the coronary artery calcification in type 1 diabetes study. J Diabetes Complications. 2016 May-Jun;30(4):586-90. PubMed PMID: 26936306

Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Achieving clinical guideline goals is associated with better insulin sensitivity and cardiopulmonary health in youth with type 1 diabetes. Oral presentation, International Society for Pediatric and Adolescent Diabetes, 2016.

Vigers T, Pyle L, DeVoogd R, Zemanick E, Martiniano S, Sagel S, Chan C. Continuous glucose monitoring in CF youth before and after ivacaftor/lumacaftor. Poster presentation, North American Cystic Fibrosis Conference, 2016.

Triolo TM, Maahs DM, Pyle L, Slover R, Buckingham B, Cheng P, DiMeglio LA, Bremer AA, Weinzimer SA, Chase HP. Effects of Frequency of Sensor-Augmented Pump Use on HbA1c and C-Peptide Levels in the First Year of Type 1 Diabetes. Diabetes Care. 2016 Apr;39(4):e61-2. PubMed PMID: 26895885

Pyle L, Bergman BC, Nadeau KJ, Cree-Green M. Modeling changes in glucose and glycerol rates of appearance when true basal rates of appearance cannot be readily determined. Am J Physiol Endocrinol Metab. 2016 Mar 1;310(5):E323-31. PubMed PMID: 26714848

Hurst AL, Olson D, Somme S, Child J, Pyle L, Ranade D, Stamatoiu A, Crombleholme T, Parker SK. Once-Daily Ceftriaxone Plus Metronidazole Versus Ertapenem and/or Cefoxitin for Pediatric Appendicitis. J Pediatric Infect Dis Soc. 2015 Dec 24. [Epub ahead of print] PubMed PMID: 26703242

Branscomb R, Vigers T, Campbell K, Pyle L, Nadeau K, Simon S, Chan CL. The relationship between actigraphy and continuous glucose monitoring in youth with cystic fibrosis. Oral presentation, Western Medical Research Conference (accepted).

Stuppy J, Cree-Green M, Bergman BC, Coe GV, Baumgartner AD, Bacon S, Sherzinger A, Pyle L, Nadeau KJ. Youth with type 1 diabetes have hepatic and peripheral insulin resistance. Oral presentation, Western Medical Research Conference (accepted).

Bjornstad P, Roncal C, Milagres T, Pyle L, Lanaspa MA, Bishop FK, Snell-Bergeon JK, Johnson RJ, Wadwa RP, Maahs DM. Hyperfiltration and uricosuria in adolescents with type 1 diabetes. Pediatr Nephrol. 2016 May;31(5):787-93. PubMed PMID: 26701836

Klingensmith GJ, Pyle L, Nadeau KJ, Barbour LA, Goland RS, Willi SM, Linder B, White NH. Pregnancy Outcomes in Youth With Type 2 Diabetes: The TODAY Study Experience. Diabetes Care. 2016 Jan;39(1):122-9. PubMed PMID: 26628417

Stewart CL, Acker SN, Pyle LL, Kulungowski A, Cadnapaphornchai M, Bruny JL, Karrer F. Factors associated with peritoneal dialysis catheter complications in children. J Pediatr Surg. 2016 Jan;51(1):159-62. PubMed PMID: 26572851

Cree-Green M, Maahs DM, Ferland A, Hokanson JE, Wang H, Pyle L, Kinney GL, King M, Eckel RH, Nadeau KJ. Lipoprotein subfraction cholesterol distribution is more atherogenic in insulin resistant adolescents with type 1 diabetes. Pediatr Diabetes. 2016 Jun;17(4):257-65. PubMed PMID: 26080650

Kelsey MM, Geffner ME, Guandalini C, Pyle L, Tamborlane WV, Zeitler PS, White NH. Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY study. Pediatr Diabetes. 2016 May;17(3):212-21. PubMed PMID: 25690268

Chan CL, Pyle L, Kelsey M, Newnes L, Zeitler PS, Nadeau KJ. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin. Pediatr Diabetes. 2016 May;17(3):206-11. PubMed PMID: 25652226

Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) Studies. Pediatr Diabetes. 2017 Oct 30. [Epub ahead of print] PubMed PMID: 29082640

Bjornstad P, Pyle L, Cherney DZI, Johnson RJ, Sippl R, Wong R, Rewers M, Snell-Bergeon JK. Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study. Nephrol Dial Transplant. 2017 Aug 21. [Epub ahead of print] PubMed PMID: 28992280

Alonso GT, Pyle L, Frohnert B. Change in hemoglobin A1c one year following the 2014 American Diabetes Association guideline update. Diabetes Res Clin Pract. 2017 Jul;129:169-172. PubMed PMID: 28528078

Spruiell MD, Searns JB, Heare TC, Roberts JL, Wylie E, Pyle L, Donaldson N, Stewart JR, Heizer H, Reese J, Scott HF, Pearce K, Anderson CJ, Erickson M, Parker SK. Clinical Care Guideline for Improving Pediatric Acute Musculoskeletal Infection Outcomes. J Pediatric Infect Dis Soc. 2017 Sep 1;6(3):e86-e93. PubMed PMID: 28419275

Cree-Green M, Cai N, Thurston JE, Coe GV, Newnes L, Garcia-Reyes Y, Baumgartner AD, Pyle L, Nadeau KJ. Using simple clinical measures to predict insulin resistance or hyperglycemia in girls with polycystic ovarian syndrome. Pediatr Diabetes. 2018 Sep 23. [Epub ahead of print] PubMed PMID: 30246333

McClain MR, Klingensmith GJ, Anderson B, Berget C, Cain C, Shea J, Campbell K, Pyle L, Raymond JK. Team Clinic: Group Approach to Care of Early Adolescents With Type 1 Diabetes. Diabetes Spectr. 2018 Aug;31(3):273-278. PubMed PMID: 30140144

Maddux AB, Hiller TD, Overdier KH, Pyle LL, Douglas IS. Innate Immune Function and Organ Failure Recovery in Adults With Sepsis. J Intensive Care Med. 2017 Jan 1;:885066617701903. [Epub ahead of print] PubMed PMID: 28372498

Li A, Vigers T, Pyle L, Zemanick E, Nadeau K, Sagel SD, Chan CL. Continuous glucose monitoring in youth with cystic fibrosis treated with lumacaftor-ivacaftor. J Cyst Fibros. 2018 Aug 10. [Epub ahead of print] PubMed PMID: 30104123

Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb PA, Steck AK. Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. 2018 Jul 30. [Epub ahead of print] PubMed PMID: 30061316

Simon SL, Vigers T, Campbell K, Pyle L, Branscomb R, Nadeau KJ, Chan CL. Reduced insulin sensitivity is correlated with impaired sleep in adolescents with cystic fibrosis. Pediatr Diabetes. 2018 Nov;19(7):1183-1190. PubMed PMID: 30022572

Cree-Green M, Stuppy JJ, Thurston J, Bergman BC, Coe GV, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Youth With Type 1 Diabetes Have Adipose, Hepatic, and Peripheral Insulin Resistance. J Clin Endocrinol Metab. 2018 Oct 1;103(10):3647-3657. PubMed PMID: 30020457

Alonso GT, Hink R, De Georgeo MR, Vidal K, Thomas S, Swaschnig D, Spiegel G, Owen S, Thurston J, Pyle L, Slover R. Improving the Insulin Pump Initiation Process for Pediatric Patients with Type 1 Diabetes through Application of Lean Quality Improvement Methods. Perm J. 2018 Jul 12;22. PubMed PMID: 30005730

Kaur H, Joshee P, Franquemont S, Baumgartner A, Thurston J, Pyle L, Nadeau KJ, Shah VN. Bone mineral content and bone density is lower in adolescents with type 1 diabetes: A brief report from the RESISTANT and EMERALD studies. J Diabetes Complications. 2018 Oct;32(10):931-933. PubMed PMID: 29980432

Cree-Green M, Xie D, Rahat H, Garcia-Reyes Y, Bergman BC, Scherzinger A, Diniz Behn C, Chan CL, Kelsey MM, Pyle L, Nadeau KJ. Oral Glucose Tolerance Test Glucose Peak Time Is Most Predictive of Prediabetes and Hepatic Steatosis in Obese Girls. J Endocr Soc. 2018 Jun 1;2(6):547-562. PubMed PMID: 29942919

Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schafer M, Pyle L, Regensteiner JG, Reusch JEB, Nadeau KJ. Leptin is associated with cardiopulmonary fitness independent of body-mass index and insulin sensitivity in adolescents with type 1 diabetes: a brief report from the EMERALD study. J Diabetes Complications. 2017 May;31(5):850-853. PubMed PMID: 28336216

Cree-Green M, Cai N, Pyle L, Ringham B, Brown MS, Newcomer BR, Nadeau KJ, Dabelea D. Insulin Resistance in Youth Without Diabetes Is Not Related to Muscle Mitochondrial Dysfunction. J Clin Endocrinol Metab. 2017 May 1;102(5):1652-1660. PubMed PMID: 28204552

Messacar K, Campbell K, Pearce K, Pyle L, Hurst AL, Child J, Parker SK. A Handshake From Antimicrobial Stewardship Opens Doors for Infectious Disease Consultations. Clin Infect Dis. 2017 May 15;64(10):1449-1452. PubMed PMID: 28186533

Young BE, Patinkin ZW, Pyle L, de la Houssaye B, Davidson BS, Geraghty S, Morrow AL, Krebs N. Markers of Oxidative Stress in Human Milk do not Differ by Maternal BMI But are Related to Infant Growth Trajectories. Matern Child Health J. 2017 Jun;21(6):1367-1376. PubMed PMID: 28138825

Stewart CL, Acker SN, Pyle L, Smith DS, Bensard DD, Moulton SL. Mapping pediatric injuries to target prevention, education, and outreach. J Pediatr Surg. 2017 Aug;52(8):1287-1291. PubMed PMID: 28073490

Murphy-Zane MS, Pyle L. Reliability of the Anterior Humeral Line Index Compared With the Gartland Classification for Posteriorly Hinged Supracondylar Humerus Fractures. Orthopedics. 2018 Jul 1;41(4):e502-e505. PubMed PMID: 29708571

Chan CL, Hope E, Thurston J, Vigers T, Pyle L, Zeitler PS, Nadeau KJ. Hemoglobin A(1c) Accurately Predicts Continuous Glucose Monitoring-Derived Average Glucose in Youth and Young Adults With Cystic Fibrosis. Diabetes Care. 2018 Jul;41(7):1406-1413. PubMed PMID: 29674323

Chan CL, Vigers T, Pyle L, Zeitler PS, Sagel SD, Nadeau KJ. Continuous glucose monitoring abnormalities in cystic fibrosis youth correlate with pulmonary function decline. J Cyst Fibros. 2018 Mar 23. [Epub ahead of print] PubMed PMID: 29580828

Bjornstad P, Johnson RJ, Snell-Bergeon JK, Pyle L, Davis A, Foster N, Cherney DZ, Maahs DM. Albuminuria is associated with greater copeptin concentrations in men with type 1 diabetes: A brief report from the T1D exchange Biobank. J Diabetes Complications. 2017 Feb;31(2):387-389. PubMed PMID: 27979439

Bjornstad P, Maahs DM, Roncal CA, Snell-Bergeon JK, Shah VN, Milagres T, Ellis SL, Hatch M, Chung LT, Rewers MJ, Garg S, Cherney DZ, Pyle L, Nadeau KJ, Johnson RJ. Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes. Diabetes Obes Metab. 2018 Jul;20(7):1776-1780. PubMed PMID: 29498467

Forlenza GP, Pyle LL, Maahs DM, Dunn TC. Ambulatory glucose profile analysis of the juvenile diabetes research foundation continuous glucose monitoring dataset-Applications to the pediatric diabetes population. Pediatr Diabetes. 2017 Nov;18(7):622-628. PubMed PMID: 27878929

Millstein RJ, Pyle LL, Bergman BC, Eckel RH, Maahs DM, Rewers MJ, Schauer IE, Snell-Bergeon JK. Sex-specific differences in insulin resistance in type 1 diabetes: The CACTI cohort. J Diabetes Complications. 2018 Apr;32(4):418-423. PubMed PMID: 29449137

Milan M, Jhajj S, Stewart C, Pyle L, Moulton S. Helmet use and injury severity among pediatric skiers and snowboarders in Colorado. J Pediatr Surg. 2017 Feb;52(2):349-353. PubMed PMID: 27876383

Chan CL, Pyle L, Kelsey MM, Newnes L, Baumgartner A, Zeitler PS, Nadeau KJ. Alternate glycemic markers reflect glycemic variability in continuous glucose monitoring in youth with prediabetes and type 2 diabetes. Pediatr Diabetes. 2017 Nov;18(7):629-636. PubMed PMID: 27873436

Nomura Y, Garcia M, Child J, Hurst AL, Hyman D, Poppy A, Palmer C, Ranade D, Pyle L, Parker SK, Provider selected order indications improve appropriateness of antimicrobial orders. American Journal of Health-System Pharmacy (in press).

Cree-Green M, Rahat H, Newcomer BR, Bergman BC, Brown MS, Coe GV, Newnes L, Bacon S, Thurston JE, Pyle L, Sherzinger A, Nadeau KJ. Insulin resistance, hyperinsulinemia and mitochondria dysfunction in non-obese girls with polycystic ovarian syndrome. Journal of the Endocrine Society (in press).

Branscomb R, Vigers T, Campbell K, Pyle L, Nadeau K, Simon S, Chan CL. The relationship between actigraphy and continuous glucose monitoring in youth with cystic fibrosis. Oral presentation, Western Medical Research Conference, 2017.

Stuppy J, Cree-Green M, Bergman BC, Coe GV, Baumgartner AD, Bacon S, Sherzinger A, Pyle L, Nadeau KJ. Youth with type 1 diabetes have hepatic and peripheral insulin resistance. Oral presentation, Western Medical Research Conference, 2017.

Bjornstad P, Pyle L, Johnson R., Sippl R, Wong R, Rewers R, Snell-Bergeon JK. Plasma biomarkers predict diabetic kidney disease (DKD) in adults with type 1 diabetes (T1D) over a 12 year follow-up: CACTI study. Oral presentation, ENDO 2017.

Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, Pöllinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW. Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. J Clin Invest. 2018 May 1;128(5):1888-1902. PubMed PMID: 29438107

Shah V, Pyle L, Joshee P, Ostendorf D, Kohrt WM, Alman A, Snell-Bergeon JK. Trabecular bone score is lower in adults with type 1 diabetes and is related to visceral and pericardial fat but not body mass index or subcutaneous fat. Poster presentation, ENDO 2017.

Cree-Green M, Cai NM, Thurston JE, Coe GV, Newnes L, Baumgartner AD, Pyle L, Nadeau KJ. Predicting insulin resistance in adolescent girls with PCOS. Oral presentation, ENDO 2017 (accepted).

Nomura Y, Garcia M, Child J, Hurst AL, Hyman D, Poppy A, Palmer C, Ranade D, Pyle L, Parker SK. Effect of provider-selected order indications on appropriateness of antimicrobial orders in a pediatric hospital. Am J Health Syst Pharm. 2018 Feb 15;75(4):213-221. PubMed PMID: 29436467

Majidi S, Fouts A, Pyle L, Chambers C, Armstrong T, Wang Z, Batish SD, Klingensmith G, Steck AK. Can Biomarkers Help Target Maturity-Onset Diabetes of the Young Genetic Testing in Antibody-Negative Diabetes?. Diabetes Technol Ther. 2018 Feb;20(2):106-112. PubMed PMID: 29355436

Shah VN, Sippl R, Joshee P, Pyle L, Kohrt WM, Schauer IE, Snell-Bergeon JK. Trabecular bone quality is lower in adults with type 1 diabetes and is negatively associated with insulin resistance. Osteoporos Int. 2018 Mar;29(3):733-739. PubMed PMID: 29290026

Cree-Green M, Rahat H, Newcomer BR, Bergman BC, Brown MS, Coe GV, Newnes L, Garcia-Reyes Y, Bacon S, Thurston JE, Pyle L, Scherzinger A, Nadeau KJ. Insulin Resistance, Hyperinsulinemia, and Mitochondria Dysfunction in Nonobese Girls With Polycystic Ovarian Syndrome. J Endocr Soc. 2017 Jul 1;1(7):931-944. PubMed PMID: 29264544

Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) Studies. Pediatr Diabetes. 2018 May;19(3):436-442. PubMed PMID: 29082640

Bjornstad P, Pyle L, Cherney DZI, Johnson RJ, Sippl R, Wong R, Rewers M, Snell-Bergeon JK. Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study. Nephrol Dial Transplant. 2018 Jul 1;33(7):1189-1196. PubMed PMID: 28992280

Nokoff NJ, Thurston JE, Hilkin A, Pyle L, Zeitler P, Nadeau KJ, Santoro N, Kelsey MM. Sex differences in effects of obesity on glucose metabolism and reproductive hormones in puberty: the Health Influences of Puberty study. Oral presentation, ENDO 2017.

Cree-Green M, Gupta A, Coe GV, Baumgartner AD, Pyle L, Reusch JE, Brown MS, Newcomer BR, Nadeau KJ. Insulin resistance in type 2 diabetes youth relates to serum free fatty acids and muscle mitochondrial dysfunction. J Diabetes Complications. 2017 Jan;31(1):141-148. PubMed PMID: 27839922

Polsky S, Garcetti R, Joshee P, Pyle L, Snell-Bergeon JK, Demmitt JK, Vigers T, Garg SK. Continuous glucose monitoring (CGM) use throughout pregnancies associated with type 1 diabetes. Poster presentation, American Diabetes Association 2017.

Stanek K, Youngkin E, Pyle L, Raymond JK, Majidi S. Diabetes management in patients with Autism Spectrum Disorder. Poster presentation, American Diabetes Association 2017.

Branscomb R, Vigers T, Campbell K, Pyle L, Nadeau K, Simon S, Chan CL. Continuous glucose monitoring, insulin resistance, and sleep in adolescents with cystic fibrosis. Poster presentation, Associated Professional Sleep Societies 2017.

Mullin BC, Pyle L, Haraden D, Riederer J, Brim N, Kaplan D, Novins D. A Preliminary Multimethod Comparison of Sleep Among Adolescents With and Without Generalized Anxiety Disorder. J Clin Child Adolesc Psychol. 2017 Mar-Apr;46(2):198-210. PubMed PMID: 27736237

Triolo T, Fouts A, Pyle L, Yu L, Muller S, Gottlieb P, Steck AK, Type 1 Diabetes TrialNet Study Group. Development of islet autoimmunity and type 1 diabetes in twins and siblings. Oral presentation, American Diabetes Association 2017.

Thurston J, Cree-Green M, Strand M, Grunwald G, Stuppy J, Bergman BC, Baumgartner AD, Bacon S, Nadeau KJ, Pyle L. Simultaneous modeling of glucose and glycerol rates of appearance in youth with and without type 1 diabetes. Poster presentation, American Diabetes Association 2017.

Alonso GT, Thomas S, Oberfeld B, Thomas S, Thurston J, Pyle L. Patient web portal (PWP) activation and usage in pediatric diabetes clinic. Poster presentation, American Diabetes Association 2017.

Fouts A, Pyle L, Clark P, Dong F, Burke B, Yu L, Usmani-Brown S, Gottlieb P, Herold KC, Steck K, and the Type 1 Diabetes TrialNet Study Group. Unmethylated insulin as a marker of beta cell death and progression to type 1 diabetes in subjects at risk for diabetes. Poster presentation, American Diabetes Association 2017.

Youngkin EM, Stanek KR, Pyle L, Escobar EE, Rewers M, Steck AK, Frohnert BI. Long-term benefits of early diagnosis of type 1 diabetes. Poster presentation, American Diabetes Association 2017.

Baldelli L, Flitter B, Pyle L, Maahs DM, Klingensmith G, Slover R, Alonso GT. A survey of youth with new onset type 1 diabetes: Opportunities to reduce diabetic ketoacidosis. Pediatr Diabetes. 2017 Nov;18(7):547-552. PubMed PMID: 27726268

Triolo T, Fouts A, Pyle L, Yu L, Muller S, Gottlieb P, Steck AK, for the Type 1 Diabetes TrialNet Study Group. Development of islet autoimmunity and type 1 diabetes in twins and siblings. Oral presentation, International Society for Pediatric and Adolescent Diabetes 2017 (accepted).

Pyle L, Cree-Green M, Thurston J, Stuppy J, Bergman BC, Baumgartner AD, Bacon S, Nadeau KJ. Youth with type 2 diabetes have hepatic, adipose, and peripheral insulin resistance. Moderated presentation, International Society for Pediatric and Adolescent Diabetes 2017 (accepted).

Cree-Green M, Torres M, Scherzinger A, Pyle L, Kelsey MM, Nadeau KJ. Extreme hyperandrogenism worsens metabolic but not physical outcomes in obese adolescents with polycystic ovarian syndrome. Oral presentation, International Meeting of Pediatric Endocrinology 2017.

Kelsey MM, Xie D, Chan CL, Nadeau KJ, Pyle L, Simon S, Wu W, Cree-Gree M, Zeitler P. Relation of OGTT curve shape to markers of type 2 diabetes risk in early puberty. Poster presentation, The Obesity Society 2017.

Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Pediatr Diabetes. 2017 Sep;18(6):470-477. PubMed PMID: 27503277

Cree-Green M, Xie D, Rahat H, Garcia-Reyes Y, Bergman BC, Bacon S, Kelsey M, Chan CL, Pyle L, Nadeau KJ. Glucose peak time during OGTT is most predictive of prediabetes and MetS risk in obese girls. Poster presentation, The Obesity Society 2017.

Bjornstad P, Pyle L, Kinney GL, Rewers M, Johnson RJ, Maahs DM, Snell-Bergeon JK. Adiponectin is associated with early diabetic kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study. J Diabetes Complications. 2017 Feb;31(2):369-374. PubMed PMID: 27368123

Hilton SA, Hodges MM, Dewberry LC, Mirsky DM, Handler M, Wilkinson CC, Galan HL, Zaretsky MV, Behrendt N, Marwan AI, Pyle L, Wagner JL, Jacot JG, Zgheib C, Crombleholme TM, Liechty KW. Primary closure of fetal myelomeningocele (MMC) is associated with improved hindbrain herniation compared to patients requiring patch closure. Oral presentation, International Fetal Medicine and Surgery Society 2017.

Hurst AL, Olson D, Somme S, Child J, Pyle L, Ranade D, Stamatoiu A, Crombleholme T, Parker SK. Once-Daily Ceftriaxone Plus Metronidazole Versus Ertapenem and/or Cefoxitin for Pediatric Appendicitis. J Pediatric Infect Dis Soc. 2017 Mar 1;6(1):57-64. PubMed PMID: 26703242

Bjornstad P, Schafer M, Truong U, Cree-Green M, Pyle L, Baumgartner A, Reyes YG, Maniatis A, Nayak S, Wadwa P, Browne L, Reusch J, Nadeau KJ. Metformin improves insulin sensitivity and vascular health in youth with type 1 diabetes: a randomized controlled trial. Circulation (in press).

Simon SL, Behn CD, Cree-Green M, Kaar JK, Pyle L, Hawkins SMM, Rahat H, Garcia-Reyes Y, Wright KP, Nadeau KJ. Too late and not enough: school year sleep duration, timing, and circadian misalignment are associated with reduced insulin sensitivity in adolescents with overweight/obesity. The Journal of Pediatrics (in press).

Polsky S, Garcetti R, Pyle L, Joshee P, Snell-Bergeon J, Demmitt JK, Garg S. CGM use with or without remote monitoring during pregnancies complicated by type 1 diabetes. Poster presentation, Advanced Technologies and Treatments for Diabetes 2018.

Cree-Green M, Wiromat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Muscle insulin resistance in metabolically healthy obese youth is associated with altered fat metabolism. Poster presentation, ENDO 2018.

Leopold D, Campbell K, Pyle L, Ing R, Mulligan J, Twite M, Moulton S. Perioperative central volume status in healthy children and in children with congenital heart disease. Oral presentation, Society of Critical Care Anesthesiology (SOCCA), Association of University Anesthesiologists (AUA), and International Anesthesia Research Society (IARS) Annual Meetings 2018.

Leopold D, Campbell K, Pyle L, Ing R, Mulligan J, Twite M, Moulton S. Joint modeling and the Compensatory Reserve Index: Insight into hemodynamic compensation during the induction of general anesthesia. Oral presentation, Society of Critical Care Anesthesiology (SOCCA), Association of University Anesthesiologists (AUA), and International Anesthesia Research Society (IARS) Annual Meetings 2018.

Kelsey MM, Pyle L, Hilkin A, Johnson A, Santoro N, Zeitler PS, Nadeau KJ. Sex differences in longitudinal changes in insulin sensitivity and adipokines during puberty. Oral presentation, Pediatric Endocrine Society 2018.

Tabano DC, Nair K, Pyle L, McQueen R, Truesdale A, Steiner JF, Anderson H. Hepatitis C patient characteristics across antiviral treatment eras in a large managed care organization. Poster presentation, ISPOR 2018.

Berget C, Messer L, Pyle L, Westfall E, Forlenza G, Driscoll K. Real world use of hybrid closed loop therapy in pediatric patients with type 1 diabetes. Poster presentation, American Diabetes Association 2018.

Nadeau KJ, Bjornstad P, Schäfer M, Cree-Green M, Baumgartner A, Garcia Reyes Y, Pyle L, Maniatis A, Nayak S, Wadwa RP, Browne L, Truong U, Reusch J. Metformin improves insulin sensitivity and vascular health in youth with type 1 diabetes: the effect of MEtformin on CardiovasculaR function in AdoLescents with type 1 Diabetes (EMERALD) study. Oral presentation, American Diabetes Association 2018.

Palmer C, Schultz J, Janoff E, Pyle L. Modeling multiple longitudinal antigen-response outcomes in infants born to HIV-positive mothers. Oral presentation, International Biometrics Conference 2018.

Pyle L, Hu J, Kittelson J. Interim monitoring of incompletely observed long-term longitudinal endpoints in clinical trials. Poster presentation, International Biometrics Conference 2018.

Carreau A, Rahat H, Garcia-Reyes Y, Pyle L, Nadeau KJ, Cree-Green M. Valine metabolism is altered in obese adolescents with polycystic ovary syndrome and relates to insulin sensitivity. Poster presentation, American Diabetes Association 2018.

Wiromat P, Bjornstad P, Roncal C, Cree-Green M, Schafer M, Baumgartner A, Coe G, Reyes YG, Truong U, Pyle L, Johnson R, Nadeau KJ. Serum uromodulin inversely associates with aortic stiffness in youth with type 1 diabetes. Poster presentation, American Diabetes Association 2018.

Chan C, Steck A, Vigers T, Pyle L, Dong F, Thurston J, Rewers M, Zeitler P, Nadeau KJ. Continuous glucose monitoring in youth with pre-type 1 diabetes, cystic fibrosis, and obesity/type 2 diabetes. Poster presentation, American Diabetes Association 2018.

Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb P, Steck AK. Risk of islet and celiac autoimmunity in cotwins of probands with type 1 diabetes. Poster presentation, American Diabetes Association 2018.

Carreau A, Rahat K, Garcia-Reyes Y, Pyle L, Nadeau KJ, Cree-Green M. Amino acids and fatty acids in response to hyperinsulinemia in girls with PCOS. Poster presentation, 2018 SECIM Metabolomics Workshop and Symposium.

Hope E, Thurston J, Vigers T, Pyle L, Zeitler P, Nadeau KJ, Chan CL. Hemoglobin A1c predicts average glucose by continuous glucose monitoring in youth with cystic fibrosis. Oral presentation, Western Medical Research Conference, 2018.

Stuppy JJ, Green M, Bergman B, Thurston J, Baumgartner A, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Youth with type 2 diabetes have hepatic and peripheral IR. Oral presentation, Western Medical Research Conference, 2018.

Rahat H, Garcia-Reyes Y, Pyle L, Nadeau KJ, Green M. The branched-chain amino acid valine is higher and relates to insulin sensitivity in polycystic ovarian syndrome. Oral presentation, Western Medical Research Conference, 2018.

Snell-Bergeon J, Keshawarz A, Shah V, Kinney G, Schauer I, Pyle L. Coronary artery calcium trajectory predicts coronary artery disease events: the CACTI study. Poster presentation, American Diabetes Association 2018.

Kelsey MM, Pyle L, Hilkin A, Johnson A, Nadeau KJ, Zeitler PS. Sex differences in longitudinal insulin sensitivity and adipokines during puberty. Poster presentation, American Diabetes Association 2018.

Carreau A, Rahat H, Garcia Reyes Y, Pyle L, Nadeau KJ, Cree-Green M. Late reactive hypoglycemia as a common early sign of glycemic dysfunction in obese adolescent girls. Poster presentation, American Diabetes Association 2018.

Gerard Gonzalez A, Brady AC, Klingensmith GJ, Pyle L, Thurston J. Novel, culturally sensitive shared group appointment program for Hispanic pediatric type 1 diabetes patients is feasible, improves technology uptake, and has promising results on better diabetes outcomes. Poster presentation, American Diabetes Association 2018.

Keshawarz A, Pyle L, Alman AC, Sassano C, Westfeldt E, Sippl RM, Snell-Bergeon JK. Pericadial adipose tissue and coronary artery calcium in type 1 diabetes – the CACTI study. Poster presentation, American Diabetes Association 2018.

Carreau A, Pyle L, Garcia-Reyes Y, Rahat H, Jensen T, Nadeau KJ, Cree-Green M. Clinical prediction score to identify hepatic steatosis in adolescents with polycystic ovarian syndrome. Poster presentation, Diabetes Canada 2018.

Cree-Green M, Wiromrat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Muscle Insulin Resistance in Youth with Obesity and Normoglycemia is Associated with Altered Fat Metabolism. Obesity (Silver Spring). 2019 Dec;27(12):2046-2054. PubMed PMID: 31659873

Vigers T, Chan CL, Snell-Bergeon J, Bjornstad P, Zeitler PS, Forlenza G, Pyle L. cgmanalysis: An R package for descriptive analysis of continuous glucose monitor data. PLoS One. 2019;14(10):e0216851. PubMed PMID: 31603912

Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017. Diabetes Care. 2019 Oct 10. [Epub ahead of print] PubMed PMID: 31601639

Keshawarz A, Pyle L, Alman A, Sassano C, Westfeldt E, Sippl R, Snell-Bergeon J. Type 1 Diabetes Accelerates Progression of Coronary Artery Calcium Over the Menopausal Transition: The CACTI Study. Diabetes Care. 2019 Dec;42(12):2315-2321. PubMed PMID: 31558547

Srinivasan Sridhar V, Ambinathan JPN, Kretzler M, Pyle LL, Bjornstad P, Eddy S, Cherney DZ, Reich HN. Renal SGLT mRNA expression in human health and disease: a study in two cohorts. Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1224-F1230. PubMed PMID: 31545924

Sherk VD, Vigers T, Pyle L, Snell-Bergeon JK, Nadeau KJ, Rickels MR, Miller KM, Greenbaum CJ, Shah VN. Acute Hyperinsulinemia Alters Bone Turnover in Women and Men With Type 1 Diabetes. JBMR Plus. 2020 Sep;4(9):e10389. PubMed PMID: 32995692

Wiromrat P, Bjornstad P, Vinovskis C, Chung LT, Roncal C, Pyle L, Lanaspa MA, Johnson RJ, Cherney DZ, Reznick-Lipina TK, Bishop F, Maahs DM, Wadwa RP. Elevated copeptin, arterial stiffness, and elevated albumin excretion in adolescents with type 1 diabetes. Pediatr Diabetes. 2019 Dec;20(8):1110-1117. PubMed PMID: 31433534

Buyers E, Sass AE, Severn CD, Pyle L, Cree-Green M. 12-month Continuation of the Etonogestrel Implant in Adolescents with Polycystic Ovary Syndrome. J Pediatr Adolesc Gynecol. 2020 Sep 9. [Epub ahead of print] PubMed PMID: 32919086

Simmons KM, Fouts A, Pyle L, Clark P, Dong F, Yu L, Usmani-Brown S, Gottlieb P, Herold KC, Steck AK. Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes. Int J Mol Sci. 2019 Aug 8;20(16). PubMed PMID: 31398795

Champakanath A, Keshawarz A, Pyle L, Snell-Bergeon JK, Shah VN. Fracture risk assessment (FRAX) without BMD and risk of major osteoporotic fractures in adults with type 1 diabetes. Bone. 2020 Aug 24;:115614. [Epub ahead of print] PubMed PMID: 32853853

Kaur H, Schneider N, Pyle L, Campbell K, Akturk HK, Shah VN. Efficacy of Hybrid Closed-Loop System in Adults with Type 1 Diabetes and Gastroparesis. Diabetes Technol Ther. 2019 Aug 16. [Epub ahead of print] PubMed PMID: 31347928

Carreau AM, Pyle L, Garcia-Reyes Y, Rahat H, Vigers T, Jensen T, Scherzinger A, Nadeau KJ, Cree-Green M. Clinical prediction score of nonalcoholic fatty liver disease in adolescent girls with polycystic ovary syndrome (PCOS-HS index). Clin Endocrinol (Oxf). 2019 Oct;91(4):544-552. PubMed PMID: 31301251

Wiromrat P, Bjornstad P, Roncal C, Pyle L, Johnson RJ, Cherney DZ, Lipina T, Bishop F, Maahs DM, Wadwa RP. Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes. J Diabetes Complications. 2019 Sep;33(9):648-650. PubMed PMID: 31253490

Benson J, Severn C, Hudnut-Beumler J, Simon SL, Abramson N, Shomaker LB, Gulley LD, Taylor A, Kelsey MM, Nadeau KJ, Zeitler PS, Pyle L, Cree-Green M. Depression in Girls With Obesity and Polycystic Ovary Syndrome and/or Type 2 Diabetes. Can J Diabetes. 2020 Aug;44(6):507-513. PubMed PMID: 32792104

Wiromrat P, Bjornstad P, Roncal C, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Truong U, Pyle L, Johnson RJ, Nadeau KJ. Serum uromodulin inversely associates with aortic stiffness in youth with type 1 diabetes: A brief report from EMERALD study. J Diabetes Complications. 2019 Jun;33(6):434-436. PubMed PMID: 31003921

Nokoff N, Thurston J, Hilkin A, Pyle L, Zeitler PS, Nadeau KJ, Santoro N, Kelsey MM. Sex Differences in Effects of Obesity on Reproductive Hormones and Glucose Metabolism in Early Puberty. J Clin Endocrinol Metab. 2019 Oct 1;104(10):4390-4397. PubMed PMID: 30985874

Cree-Green M, Bergman BC, Cengiz E, Fox LA, Hannon TS, Miller K, Nathan B, Pyle L, Kahn D, Tansey M, Tichy E, Tsalikian E, Libman I, Nadeau KJ. Metformin Improves Peripheral Insulin Sensitivity in Youth With Type 1 Diabetes. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3265-3278. PubMed PMID: 30938764

Pascual AB, Pyle L, Nieto J, Klingensmith GJ, Gonzalez AG. Novel, culturally sensitive, shared medical appointment model for Hispanic pediatric type 1 diabetes patients. Pediatr Diabetes. 2019 Jun;20(4):468-473. PubMed PMID: 30938029

Shah VN, Joshee P, Sippl R, Pyle L, Vigers T, Carpenter RD, Kohrt W, Snell-Bergeon JK. Type 1 diabetes onset at young age is associated with compromised bone quality. Bone. 2019 Jun;123:260-264. PubMed PMID: 30936041

Messer LH, Campbell K, Pyle L, Forlenza GP. Basal-IQ technology in the real world: satisfaction and reduction of diabetes burden in individuals with type 1 diabetes. Diabet Med. 2020 Aug 7;:e14381. [Epub ahead of print] PubMed PMID: 32767401

Stanek KR, Youngkin EM, Pyle LL, Raymond JK, Driscoll KA, Majidi S. Prevalence, characteristics, and diabetes management in children with comorbid autism spectrum disorder and type 1 diabetes. Pediatr Diabetes. 2019 Aug;20(5):645-651. PubMed PMID: 30912248

Vinovskis C, Li LP, Prasad P, Tommerdahl K, Pyle L, Nelson RG, Pavkov ME, van Raalte D, Rewers M, Pragnell M, Mahmud FH, Cherney DZ, Johnson RJ, Nadeau KJ, Bjornstad P. Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes. Diabetes. 2020 Jul 31. [Epub ahead of print] PubMed PMID: 32737116

Simon SL, McWhirter L, Diniz Behn C, Bubar KM, Kaar JL, Pyle L, Rahat H, Garcia-Reyes Y, Carreau AM, Wright KP, Nadeau KJ, Cree-Green M. Morning Circadian Misalignment Is Associated With Insulin Resistance in Girls With Obesity and Polycystic Ovarian Syndrome. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3525-3534. PubMed PMID: 30888398

Carreau AM, Xie D, Garcia-Reyes Y, Rahat H, Bartlette K, Behn CD, Pyle L, Nadeau KJ, Cree-Green M. Good agreement between hyperinsulinemic-euglycemic clamp and 2 hours oral minimal model assessed insulin sensitivity in adolescents. Pediatr Diabetes. 2020 Jun 26. [Epub ahead of print] PubMed PMID: 32592269

Triolo TM, Pyle L, Seligova S, Yu L, Gottlieb PA, Steck AK. Risk of Islet and Celiac Autoimmunity in Cotwins of Probands With Type 1 Diabetes. J Endocr Soc. 2020 Jun 1;4(6):bvaa053. PubMed PMID: 32537543

Van Hove JLK, Freehauf CL, Ficicioglu C, Pena LDM, Moreau KL, Henthorn TK, Christians U, Jiang H, Cowan TM, Young SP, Hite M, Friederich MW, Stabler SP, Spector EB, Kronquist KE, Thomas JA, Emmett P, Harrington MJ, Pyle L, Creadon-Swindell G, Wempe MF, MacLean KN. Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ß-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial. J Inherit Metab Dis. 2019 May;42(3):424-437. PubMed PMID: 30873612

Thompson T, Howell S, Davis S, Wilson R, Janusz J, Boada R, Pyle L, Tartaglia N. Current survey of early childhood intervention services in infants and young children with sex chromosome aneuploidies. Am J Med Genet C Semin Med Genet. 2020 Jun;184(2):414-427. PubMed PMID: 32449585

Cree-Green M, Carreau AM, Rahat H, Garcia-Reyes Y, Bergman BC, Pyle L, Nadeau KJ. Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E707-E718. PubMed PMID: 30753112

Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP. Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients. Blood Adv. 2019 Feb 12;3(3):350-359. PubMed PMID: 30718242

Hsu SC, Bartz S, Pyle L, Fete M, Davis S, Ohman-Hanson R, Fete TJ, Motil KJ. Growth failure in focal dermal hypoplasia. Am J Med Genet A. 2019 Apr;179(4):628-633. PubMed PMID: 30693654

Bjornstad P, Schäfer M, Truong U, Cree-Green M, Pyle L, Baumgartner A, Garcia Reyes Y, Maniatis A, Nayak S, Wadwa RP, Browne LP, Reusch JEB, Nadeau KJ. Metformin Improves Insulin Sensitivity and Vascular Health in Youth With Type 1 Diabetes Mellitus. Circulation. 2018 Dec 18;138(25):2895-2907. PubMed PMID: 30566007

Cree-Green M, Wiromrat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Youth with type 2 diabetes have hepatic, peripheral, and adipose insulin resistance. Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E186-E195. PubMed PMID: 30562061

Simon SL, Behn CD, Cree-Green M, Kaar JL, Pyle L, Hawkins SMM, Rahat H, Garcia-Reyes Y, Wright KP Jr, Nadeau KJ. Too Late and Not Enough: School Year Sleep Duration, Timing, and Circadian Misalignment Are Associated with Reduced Insulin Sensitivity in Adolescents with Overweight/Obesity. J Pediatr. 2019 Feb;205:257-264.e1. PubMed PMID: 30497764

Simmons KM, Mitchell AM, Alkanani AA, McDaniel KA, Baschal EE, Armstrong T, Pyle L, Yu L, Michels AW. Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02 . Diabetes. 2020 Aug;69(8):1763-1769. PubMed PMID: 32439825

Cree-Green M, Cai N, Thurston JE, Coe GV, Newnes L, Garcia-Reyes Y, Baumgartner AD, Pyle L, Nadeau KJ. Using simple clinical measures to predict insulin resistance or hyperglycemia in girls with polycystic ovarian syndrome. Pediatr Diabetes. 2018 Dec;19(8):1370-1378. PubMed PMID: 30246333

Polsky S, Garcetti R, Pyle L, Joshee P, Demmitt JK, Snell-Bergeon JK. Continuous glucose monitor use with and without remote monitoring in pregnant women with type 1 diabetes: A pilot study. PLoS One. 2020;15(4):e0230476. PubMed PMID: 32298269

McClain MR, Klingensmith GJ, Anderson B, Berget C, Cain C, Shea J, Campbell K, Pyle L, Raymond JK. Team Clinic: Group Approach to Care of Early Adolescents With Type 1 Diabetes. Diabetes Spectr. 2018 Aug;31(3):273-278. PubMed PMID: 30140144

Ravi SJ, Coakley A, Vigers T, Pyle L, Forlenza GP, Alonso T. Pediatric Medicaid Patients With Type 1 Diabetes Benefit From Continuous Glucose Monitor Technology. J Diabetes Sci Technol. 2020 Mar 14;:1932296820906214. [Epub ahead of print] PubMed PMID: 32172603

Li A, Vigers T, Pyle L, Zemanick E, Nadeau K, Sagel SD, Chan CL. Continuous glucose monitoring in youth with cystic fibrosis treated with lumacaftor-ivacaftor. J Cyst Fibros. 2019 Jan;18(1):144-149. PubMed PMID: 30104123

Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb PA, Steck AK. Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. 2019 Feb;42(2):192-199. PubMed PMID: 30061316

Maddux AB, Hiller TD, Overdier KH, Pyle LL, Douglas IS. Innate Immune Function and Organ Failure Recovery in Adults With Sepsis. J Intensive Care Med. 2019 Jun;34(6):486-494. PubMed PMID: 28372498

Lytvyn Y, Bjornstad P, Katz A, Singh SK, Godoy LC, Chung LT, Vinovskis CL, Pyle L, Roussel R, Perkins BA, Cherney D. SGLT2 inhibition increases serum copeptin in young adults with type 2 diabetes. Diabetes and Metabolism (in press).

Berget C, Messer LH, Vigers T, Wadwa RP, Slover R, Pyle L, Driscoll KA, Forlenza G. Hybrid Closed Loop therapy in the real world: 6 month clinical observation of youth with type 1 diabetes. Oral presentation, ATTD 2019.

Sopfe J, Vigers T, Pyle L, Giller RH, Forlenza GP. Safety and Accuracy of Factory-Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation. Diabetes Technol Ther. 2020 Oct;22(10):727-733. PubMed PMID: 32105513

Vigers T, Chan CL, Snell-Bergeon J, Bjornstad P, Zeitler PS, Forlenza G, Pyle L. An R package for analysis of continuous glucose monitor data. E-poster presentation, ATTD 2019.

Xie D, Carreau AM, Reyes YG, Rahat H, Bartlette K, Behn CD, Pyle L, Nadeau KJ, Cree-Green M. Validation of surrogate models to assess tissue and whole body insulin resistance among high risk adolescent girls. Oral presentation, Endo 2019.

Kelsey MM, Pyle L, Hilkin A, Severn CD, Utzschneider K, Van Pelt RE, Nadeau KJ, Zeitler PS. The Impact of Obesity On Insulin Sensitivity and Secretion During Pubertal Progression: A Longitudinal Study. J Clin Endocrinol Metab. 2020 May 1;105(5). PubMed PMID: 31996919

Kelsey MM, Pyle L, Hilkin A, Van Pelt RE, Zeitler PS, Nadeau KJ. Two year treatment with metformin during puberty is associated with improvements in body composition, but not in insulin sensitivity or beta cell function in obese youth. Poster presentation, Endo 2019.

Jobira B, Frank D, Robertson CE, Ir D, Pyle L, Gross Su, Friedman J, Pendleton W, Hilkin A, Nadeau KJ, Kelsey M. Exploring the relationship between the gut microbiome and puberty in girls at risk for type 2 diabetes. Oral presentation, Pediatric Academic Societies 2019.

Gourgari E, Gordon SM, Vigers T, Pyle L, Ma J, Nadeau K, Remaley AT. Effect of metformin on the HDL proteome of youth with T1DM. Oral presentation, Pediatric Academic Societies 2019.

Tommerdahl KL, Bjornstad P, Cree-Green M, Baumgartner AD, Pyle L, Nadeau KJ. Results from the Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) Study: Renal and Inflammatory Outcomes. Poster presentation, Pediatric Academic Societies 2019.

Kaar JL, Hudnut-Beumler J, Pyle L, Kelsey MM, Nadeau KJ, Zeitler P, Cree-Green M. Predictors for development of type 2 diabetes in obese girls within two years of diagnosis of polycystic ovarian syndrome. Poster presentation, Pediatric Academic Societies 2019.

Ravi S, Pyle L, Majidi S. Adolescent self-care and knowledge education in diabetes – improved by texting? Poster presentation, Pediatric Academic Societies 2019.

Jobira B, Frank DN, Pyle L, Silveira LJ, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M. Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota. J Clin Endocrinol Metab. 2020 Jun 1;105(6). PubMed PMID: 31970418

Hwang SS, Tong S, Pyle L, Battaglia C, McManus B, Niermeyer S, Sauaia A. Impact of state prioritization of safe infant sleep programs on supine sleep positioning for preterm and term infants. Poster presentation, Pediatric Academic Societies 2019.

Hwang SS, Tong S, Smith RA, Barfield WD, Pyle L, Battaglia C, McManus B, Niermeyer S, Sauaia A. Persistent black-white disparities in supine sleep positioning among US-born preterm infants. Poster presentation, Pediatric Academic Societies 2019.

Polsky S, Snell-Bergeon JK, Joshee P, Garcetti R, Pyle L. Glycemic variability among pregnant women with type 1 diabetes based on use of CGM Share technology. Poster presentation, American Diabetes Association 2019.

Polsky S, Pyle L, Garcetti R, Joshee P, Snell-Bergeon JK. Associations between indices of glycemic variability and gestational outcomes among pregnant women with type 1 diabetes. Poster presentation, American Diabetes Association 2019.

Duca LM, Pyle L, Khanna AD, Ong T, Kahn MG, DiGuiseppi C, Scott K, Daley MF, Costa E 3rd, Davidson AJ, Crume TL. Estimating the prevalence of congenital heart disease among adolescents and adults in Colorado adjusted for incomplete case ascertainment. Am Heart J. 2020 Mar;221:95-105. PubMed PMID: 31955128

Chan CL, Steck AK, Severn C, Pyle L, Rewers M, Zeitler PS. Lessons From Continuous Glucose Monitoring in Youth With Pre-Type 1 Diabetes, Obesity, and Cystic Fibrosis. Diabetes Care. 2020 Mar;43(3):e35-e37. PubMed PMID: 31937609

Simon S, Rahat H, Carreau AM, Garcia-Reyes Y, Halbower A, Pyle L, Nadeau KJ, Cree-Green M. Poor Sleep Is Related to Metabolic Syndrome Severity in Adolescents With PCOS and Obesity. J Clin Endocrinol Metab. 2020 Apr 1;105(4). PubMed PMID: 31901092

Messer LH, Berget C, Vigers T, Pyle L, Geno C, Wadwa RP, Driscoll KA, Forlenza GP. Real world hybrid closed-loop discontinuation: Predictors and perceptions of youth discontinuing the 670G system in the first 6 months. Pediatr Diabetes. 2020 Mar;21(2):319-327. PubMed PMID: 31885123

Snell-Bergeon JK, Pyle L, Sippl R, Polsky S. Type 1 diabetes pregnancies complicated by hypertensive disorders. Poster presentation, American Diabetes Association 2019.

Berget C, Messer LH, Vigers T, Frohnert BI, Pyle L, Wadwa RP, Driscoll KA, Forlenza GP. Six months of hybrid closed loop in the real-world: An evaluation of children and young adults using the 670G system. Pediatr Diabetes. 2020 Mar;21(2):310-318. PubMed PMID: 31837064

Hudnut-Beumler J, Kaar JL, Kelsey MM, Pyle L, Nadeau KJ, Zeitler P, Cree-Green M. Development of type 2 diabetes in obese adolescent girls with polycystic ovarian syndrome. Poster presentation, American Diabetes Association 2019.

Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers M, Rewers A. Increase in diabetic ketoacidosis at diagnosis of T1D in Colorado children, 2010-2017. Poster presentation, American Diabetes Association 2019.

Pyle L, Carreau A, Rahat H, Garcia Reyes Y, Nadeau KJ, Cree-Green M. Fasting metabolomic profiles are altered by three days of standardized diet and restricted physical activity. Poster presentation, American Diabetes Association 2019.

Lytvyn Y, Bjornstad P, Katz A, Singh SK, Godoy LC, Chung LT, Vinovskis CL, Pyle L, Roussel R, Perkins BA, Cherney D. SGLT2 inhibition increases serum copeptin in young adults with type 1 diabetes. Diabetes Metab. 2020 Jun;46(3):203-209. PubMed PMID: 31816431

Tommerdahl KL, Baumgartner K, Bjornstad P, Baumgartner AD, Pyle L, Regensteiner J, Reusch J, Nadeau KJ. Cardiovascular impact of BMI in youth with type 1 diabetes. Oral presentation, American Diabetes Association 2019.

Polsky S, Garcetti R, Pyle L, Joshee P, Demmitt JK, Snell-Bergeon JK. Continuous Glucose Monitor Use With Remote Monitoring Reduces Fear of Hypoglycemia in Pregnant Women With Type 1 Diabetes: A Pilot Study. J Diabetes Sci Technol. 2020 Jan;14(1):191-192. PubMed PMID: 31779476

Kaar J, Hudnut-Beumler J, Simon SL, Pyle L, Kelsey MM, Nadeau K, Zeitler P, Cree-Green M. Past medical history of obstructive sleep apnea predicts the development of type 2 diabetes in obese girls within two years of diagnosis of polycystic ovary syndrome. Poster presentation, SLEEP 2019.

Wiromat P, Rynders CA, Bergman BC, Pyle L, Nadeau KJ, Cree-Green M. Metabolic flexibility in response to multidose hyperinsulinemic-euglycemic clamp is similar in obese youth regardless of polycystic ovary syndrome status. Poster presentation, American Diabetes Association 2019.

Triolo T, Pyle L, Seligova S, Yu L, Simmons K, Gottlieb PA, Evans-Molina C, Steck AK. Proinsulin:C-peptide ratios in relatives of patients with type 1 diabetes. Poster presentation, American Diabetes Association 2019.

Cree-Green M, Wiromrat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Muscle Insulin Resistance in Youth with Obesity and Normoglycemia is Associated with Altered Fat Metabolism. Obesity (Silver Spring). 2019 Dec;27(12):2046-2054. PubMed PMID: 31659873

Jobira B, Frank DN, Robertson CE, Ir D, Pyle L, Silveira L, Gross S, Friedman J, Pendleton W, Nadeau KJ, Kelsey MM. The gut microbiome and puberty in girls at risk for type 2 diabetes. Poster presentation, American Diabetes Association 2019.

Vigers T, Chan CL, Snell-Bergeon J, Bjornstad P, Zeitler PS, Forlenza G, Pyle L. cgmanalysis: An R package for descriptive analysis of continuous glucose monitor data. PLoS One. 2019;14(10):e0216851. PubMed PMID: 31603912

Tommerdahl K, Baumgartner K, Bjornstad P, Buamgartner AD, Pyle L, Regensteiner J, Reusch J, Nadeau KJ. Impact of obesity on markers of cardiovascular function in youth with type 1 diabetes. Moderated poster presentation, International Society for Pediatric and Adolescent Diabetes 2019.

Putschoegl A, Pyle L, Everitt M, Miyamoto S, Pietra B, Auerbach S. Slowed progression of maximal intimal thickening by intravascular ultrasound after initiation of sirolimus. Oral presentation, International Society for Heart and Lung Transplantation Conference 2019.

Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017. Diabetes Care. 2020 Jan;43(1):117-121. PubMed PMID: 31601639

Stuppy J, Severn C, Parks EJ, Carreau AM, Garcia-Reyes Y, Rahat H, Wagner DA, Nadeau KJ, Pyle L, Cree-Green M. Increased de novo lipogenesis in hepatic steatosis regardless of polycystic ovary syndrome. Oral presentation, Western Medical Research Conference, 2019.

Cree-Green M, Ravi S, Carreau AM, Sewell R, Baumgartner A, Coe G, Bergman BC, Scherzinger A, Jensen T, Pyle L, Nadeau KJ. Nonalcoholic fatty liver disease in obese adolescent females is associated with multi-tissue insulin resistance and visceral adiposity markers. Metabol Open. 2019 Jun;2:100011. PubMed PMID: 32812939

Berget C, Messer LH, Vigers T, Pyle L, Driscoll KA, Forlenza G. HCL use fdecreases significantly across time in youth with T1D. Oral presentation (accepted), ATTD 2020.

Benjamin H, Nadeau KJ, Pyle L, Hilkin AM, Zeitler PS, Kelsey M. Longitudinal changes in abdominal fat compartmentalization during puberty. Poster presentation, Obesity Week 2019.

Jobira B, Frank DN, Kelsey MM, Garcia-Reyes Y, Pyle L, Silveira LJ, Ir D, Robertson CE, Nadeau KJ, Cree-Green M. Hepatic steatosis relates to microbiome changes in obese girls with polycystic ovary syndrome. Poster presentation, Obesity Week 2019.

Kozlova DA, Severn C, Pyle L, Cree-Green M, Nadeau KJ. Changes in insulin clearance in PCOS are driven by insulin sensitivity. Poster presentation, Obesity Week 2019.

Benson J, Severn C, Hudnut-Beumler J, Abramson N, Shomaker LB, Gulley LD, Taylor A, Kelsey MM, Nadeau KJ, Zeitler PS, Pyle L, Cree-Green M. Depression in girls with polycystic ovary syndrome and obesity. Poster presentation, Obesity Week 2019.

Sridhar V, Ambinathan J, Kretzler M, Pyle L, Bjornstad P, Eddy S, Cherney D, Reich H and the ERCB and NEPTUNE study groups. Oral presentation, Canadian Society for Nephrology 2019.

Cobry E, Berget C, Messer L, Wadwa P, Driscoll K, Pyle P, Forlenza G. Psychosocial outcomes after one year of real-world hybrid closed loop therapy in youth with type 1 diabetes. E-poster presentation, ATTD 2020.

Buyers E, Sass A, Severn CD, Pyle L, Cree-Green M. Continuation of the etonogestrel implant in adolescents with polycystic ovary syndrome. Oral presentation North American Society for Pediatric and Adolescent Gynecology 2020.

Andrisse S, Torres M, Garcia-Reyes Y, Pyle L, Nadeau KJ, Kelsey MM, Cree-Green M. Racial and ethnic differences in metabolic disease in obese adolescents with polycystic ovary syndrome. Poster presentation, ENDO 2020.

Maddux AB, Campbell K, Pyle LL, LaVelle J, Watson RS, Mourani PM, Bennett TD. Functional outcome phenotypes derived from insurance claim data in children who survived prolonged mechanical ventilation. Poster presentation, American Thoracic Society 2020.

Maddux AB, Campbell K, Pyle LL, Sierra Y, Spear M, Van KA, Grosskreuz R, Bennett TD, Buchowski M, Watson RS, Mourani PM. Accelerometry: an objective evaluation of physical functional recovery in children who survive prolonged mechanical ventilation. Poster presentation, American Thoracic Society 2020.

Levin P, Snell-Bergeon J, Vigers T, Pyle L, Bromberger L. Effective treatment of patients with uncontrolled type 2 diabetes on multiple diabetes medications by adding mealtime ultra-rapid technosphere insulin. Poster presentation, ATTD 2020.

Rydin A, Severn C, Pyle L, Reyes YG, Nadeau K, Cree-Gree M. Development of a new predictive equation for basal energy expenditure and the accuracy of current equations for overweight and obese females. Poster presentation, Pediatric Endocrine Society Annual Meeting 2020.

Kelsey MM, Benjamin H, Pyle L, Severn C, Zeitler PS, Nadeau KJ. Rise in liver fat during puberty is predicted by leptin and glycemia, but not by insulin sensitivity. Poster presentation, Pediatric Endocrine Society Annual Meeting 2020.

Jensen R, Campbell K, Pyle L, Gerard Gonzalez A. Novel culturally sensitive shared medical appointment model for high risk Latino youth with type 1 diabetes: one year follow up post pilot intervention. Poster presentation, American Diabetes Association 2020.

Cobry E, Reznick-Lepina T, Pyle L, Slover R, Thomas JF, Wadwa RP. Lower use of technology in youth with type 1 diabetes in locations distant from subspecialty care. Poster presentation, American Diabetes Association 2020.

Simmons KM, Mitchell AM, Alkanani AA, McDaniel KA, Baschal EE, Armstrong T, Pyle L, Yu L, Michels AW. Failed Genetic Protection: Type 1 Diabetes in the presence of HLA-DQB1*06:02. Oral presentation, American Diabetes Association 2020.

Snell-Bergeon JK, Schauer IE, Bergman BC, Nadeau KJ, Cree-Green M, Keshawarz A, Pyle L. Metabolites associated with insulin resistance in women with and without type 1 diabetes. Moderated poster presentation, American Diabetes Association 2020.

Jimenez V, Gulley L, Hilkin AM, Conte I, Verros M, Clark E, Casamassima M, Miller R, Bernstein R, Pyle L, Nadeau KJ, Kelsey MM, Shomaker LB. Trauma and loss-of-Control eating relate to elevated type 2 diabetes risk in adolescents. Poster presentation, American Diabetes Association 2020.

Pyle L, Carreau A, Rahat H, Garcia-Reyes Y, Nadeau KJ, Cree-Green M. Challenges in handling missing data in untargeted LC-MS metabolomics experiments. Poster presentation, International Biometric Conference 2020.

Palmer C, Driver C, Brown LD, Hobbins J, Pyle L. The use of multivariate latent class mixed effect models to predict pathological fetal growth restriction. Poster presentation, International Biometric Conference 2020.

Kelsey M, Hilkin AM, Severn C, Pyle L, Nadeau KJ, Zeitler P. Puberty is associated with a rising HbA1c, even in healthy normal weight youth. Poster presentation, American Diabetes Association 2020.

Cobry E, Berget C, Messer L, Wadwa RP, Vigers T, Pyle L, Slover R, Forlenza G. Nocturnal alarms: a potential barrier to diabetes technology use. Poster presentation, American Diabetes Association 2020.

Triolo T, Pyle L, Yu L, Gottlieb P, Steck AK and the Type 1 Diabetes TrialNet Study Group. Association of high-affinity antibodies with high-risk HLA haplotypes. Poster presentation, American Diabetes Association 2020.

Kelsey MM, Hilkin AM, Severn C, Pyle L, Nadeau KJ, Zeitler P. Puberty is associated with a rising HbA1c, even in healthy normal weight youth. Poster presentation, American Diabetes Association 2020.

Vinoskis CL, Nadeau KJ, Tommerdahl KL, Prasad PV, Li L, Pyle L, Rewers M, Pragnell M, Mahmud FH, Van raalte DHV, Cherney D, Nelson R, Bjornstad P. A metabolic mismatch between renal oxygenation and glomerular filtration rate in type 1 diabetes. Oral presentation, American Diabetes Association 2020 (ADA Presidents’ Select Abstract Presentation).

Anderson AM, Landry LG, Alkanani AA, Pyle L, Powers AC, Atkinson MA, Mathews CE, Roep BO, Michels AW, Nakayama M. Human islet T cells are highly reactive to preproinsulin in type 1 diabetes. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41). PubMed PMID: 34611019

Nunes-Moreno M, Buchanan C, Cole FS, Davis S, Dempsey A, Dowshen N, Furniss A, Kazak AE, Kerlek AJ, Margolis P, Pyle L, Razzaghi H, Reirden DH, Schwartz B, Sequeira GM, Nokoff NJ. Behavioral Health Diagnoses in Youth with Gender Dysphoria Compared with Controls: A PEDSnet Study. J Pediatr. 2021 Sep 24. [Epub ahead of print] PubMed PMID: 34571022

Hwang SS, Tong S, Pyle L, Battaglia C, McManus B, Niermeyer S, Sauaia A. Impact of State Prioritization of Safe Infant Sleep Programs on Supine Sleep Positioning for Non-Hispanic White and Non-Hispanic Black Infants. Am J Perinatol. 2021 Sep 20. [Epub ahead of print] PubMed PMID: 34544194

Chan CL, Pyle L, Vigers T, Zeitler PS, Nadeau KJ. Full The Relationship between Continuous Glucose Monitoring and OGTT in Youth and Young Adults with Cystic Fibrosis. J Clin Endocrinol Metab. 2021 Sep 19. [Epub ahead of print] PubMed PMID: 34537845

Shah VN, Snell-Bergeon JK, Demmitt JK, Joshee P, Garcetti R, Pyle L, Polsky S. Relationship Between Time-in-Range, HbA1c, and the Glucose Management Indicator in Pregnancies Complicated by Type 1 Diabetes. Diabetes Technol Ther. 2021 Nov 3. [Epub ahead of print] PubMed PMID: 34524020

Cobry E, Reznick-Lipina T, Pyle L, Slover RJ, Thomas JF, Alonso GT, Wadwa RP. Diabetes Technology Use in Remote Pediatric Patients with Type 1 Diabetes Using Clinic-to-Clinic Telemedicine. Diabetes Technol Ther. 2021 Sep 15. [Epub ahead of print] PubMed PMID: 34524007

Akturk HK, Vigers T, Forlenza GP, Champakanath A, Pyle L. Comparison of cgmanalysis, a free, open-source continuous glucose monitoring (CGM) data management and analysis software to commercially available CGM platforms: Data standardization for diabetes technology research. Diabetes Technol Ther. 2021 Sep 15. [Epub ahead of print] PubMed PMID: 34524001

Cung S, Pyle L, Nadeau K, Dabelea D, Cree-Green M, Davis SM. In-vivo skeletal muscle mitochondrial function in Klinefelter syndrome. J Investig Med. 2021 Sep 7. [Epub ahead of print] PubMed PMID: 34493629

Akturk HK, Snell-Bergeon J, Pyle L, Fivekiller E, Garg S, Cobry E. Accuracy of a breath ketone analyzer to detect ketosis in adults and children with type 1 diabetes. J Diabetes Complications. 2021 Nov;35(11):108030. PubMed PMID: 34481712

Sewell R, Buchanan CL, Davis S, Christakis DA, Dempsey A, Furniss A, Kazak AE, Kerlek AJ, Magnusen B, Pajor NM, Pyle L, Pyle LC, Razzaghi H, Schwartz BI, Vogiatzi MG, Nokoff NJ. Behavioral Health Diagnoses in Youth with Differences of Sex Development or Congenital Adrenal Hyperplasia Compared with Controls: A PEDSnet Study. J Pediatr. 2021 Aug 27. [Epub ahead of print] PubMed PMID: 34461062

Vigers T, Vanderlinden LA, Johnson RK, Carry PM, Yang I, DeFelice BC, Kaizer AM, Pyle L, Rewers M, Fiehn O, Norris JM, Kechris K. A Mediation Approach to Discovering Causal Relationships between the Metabolome and DNA Methylation in Type 1 Diabetes. Metabolites. 2021 Aug 14;11(8). PubMed PMID: 34436483

Piani F, Melena I, Severn C, Chung LT, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Obeid W, Parikh C, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Tubular injury in diabetic ketoacidosis: Results from the diabetic kidney alarm study. Pediatr Diabetes. 2021 Nov;22(7):1031-1039. PubMed PMID: 34435718

Gourgari E, Nadeau KJ, Pyle L, Playford MP, Ma J, Mehta NN, Remaley AT, Gordon SM. Effect of metformin on the high-density lipoprotein proteome in youth with type 1 diabetes. Endocrinol Diabetes Metab. 2021 Jul;4(3):e00261. PubMed PMID: 34277985

Buschur EO, Campbell K, Pyle L, Garcetti R, Joshee P, Demmitt JK, Snell-Bergeon JK, Polsky S. Exploratory Analysis of Glycemic Control and Variability Over Gestation Among Pregnant Women with Type 1 Diabetes. Diabetes Technol Ther. 2021 Nov;23(11):768-772. PubMed PMID: 34115946

Messer LH, Berget C, Pyle L, Vigers T, Cobry E, Driscoll KA, Forlenza GP. Real-World Use of a New Hybrid Closed Loop Improves Glycemic Control in Youth with Type 1 Diabetes. Diabetes Technol Ther. 2021 Jun 21. [Epub ahead of print] PubMed PMID: 34096789

Pyle L, Kelsey MM. Youth-onset type 2 diabetes: translating epidemiology into clinical trials. Diabetologia. 2021 Aug;64(8):1709-1716. PubMed PMID: 34075436

Berget C, Akturk HK, Messer LH, Vigers T, Pyle L, Snell-Bergeon J, Driscoll KA, Forlenza GP. Real-world performance of hybrid closed loop in youth, young adults, adults and older adults with type 1 diabetes: Identifying a clinical target for hybrid closed-loop use. Diabetes Obes Metab. 2021 Sep;23(9):2048-2057. PubMed PMID: 34010499

Hudnut-Beumler J, Kaar JL, Taylor A, Kelsey MM, Nadeau KJ, Zeitler P, Snell-Bergeon J, Pyle L, Cree-Green M. Development of type 2 diabetes in adolescent girls with polycystic ovary syndrome and obesity. Pediatr Diabetes. 2021 Aug;22(5):699-706. PubMed PMID: 33870630

Levin P, Hoogwerf BJ, Snell-Bergeon J, Vigers T, Pyle L, Bromberger L. Ultra Rapid-Acting Inhaled Insulin Improves Glucose Control in Patients With Type 2 Diabetes Mellitus. Endocr Pract. 2021 May;27(5):449-454. PubMed PMID: 33853718

Alonso GT, Murphy C, Pyle L, Thomas S, Ohman-Hanson R, Rewers A. Increased Prevalence of Diabetic Ketoacidosis Among Colorado Children at Diagnosis of Type 1 Diabetes During the COVID-19 Pandemic Lockdown Resolves After Reopening. Diabetes Technol Ther. 2021 Sep;23(9):663-664. PubMed PMID: 33835859

Triolo TM, Pyle L, Seligova S, Yu L, Simmons K, Gottlieb P, Evans-Molina C, Steck AK. Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes. J Transl Autoimmun. 2021;4:100089. PubMed PMID: 33748733

Kelsey MM, Hilkin A, Pyle L, Severn C, Utzschneider K, Van Pelt RE, Zeitler PS, Nadeau KJ. Two-Year Treatment With Metformin During Puberty Does Not Preserve ß-Cell Function in Youth With Obesity. J Clin Endocrinol Metab. 2021 Jun 16;106(7):e2622-e2632. PubMed PMID: 33728428

Hwang SS, Tong S, Smith RA, Barfield WD, Pyle L, Battaglia C, McManus B, Niermeyer S, Sauaia A. Persistent Racial/Ethnic Disparities in Supine Sleep Positioning among US Preterm Infants, 2000-2015. J Pediatr. 2021 Jun;233:51-57.e3. PubMed PMID: 33676934

Pyle L, Carreau AM, Rahat H, Garcia-Reyes Y, Bergman BC, Nadeau KJ, Cree-Green M. Fasting plasma metabolomic profiles are altered by three days of standardized diet and restricted physical activity. Metabol Open. 2021 Mar;9:100085. PubMed PMID: 33665598

Andrisse S, Garcia-Reyes Y, Pyle L, Kelsey MM, Nadeau KJ, Cree-Green M. Racial and Ethnic Differences in Metabolic Disease in Adolescents With Obesity and Polycystic Ovary Syndrome. J Endocr Soc. 2021 Apr 1;5(4):bvab008. PubMed PMID: 33644620

Mullin BC, Holzman JBW, Pyle L, Perks EL, Chintaluru Y, Gulley LD, Haraden DA, Hankin BL. Relationships between attention to emotion and anxiety among a community sample of adolescents. Psychol Med. 2021 Mar 1;:1-12. [Epub ahead of print] PubMed PMID: 33641686

Mitchell AM, Alkanani AA, McDaniel KA, Pyle L, Waugh K, Steck AK, Nakayama M, Yu L, Gottlieb PA, Rewers MJ, Michels AW. T-cell responses to hybrid insulin peptides prior to type 1 diabetes development. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6). PubMed PMID: 33542101

Bartlette K, Carreau AM, Xie D, Garcia-Reyes Y, Rahat H, Pyle L, Nadeau KJ, Cree-Green M, Diniz Behn C. Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration. Metabol Open. 2021 Mar;9:100078. PubMed PMID: 33511337

Sopfe J, Campbell K, Keating AK, Pyle L, Liu AK, Verneris MR, Giller RH, Forlenza GP. Glycemic variability is associated with poor outcomes in pediatric hematopoietic stem cell transplant patients. Pediatr Blood Cancer. 2020 Nov;67(11):e28626. PubMed PMID: 33480469

Jobira B, Frank DN, Silveira LJ, Pyle L, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M. Hepatic steatosis relates to gastrointestinal microbiota changes in obese girls with polycystic ovary syndrome. PLoS One. 2021;16(1):e0245219. PubMed PMID: 33465100

O'Donnell HK, Vigers T, Johnson SB, Pyle L, Wright N, Deeb LC, Driscoll KA. Pump It Up! A randomized clinical trial to optimize insulin pump self-management behaviors in adolescents with type 1 diabetes. Contemp Clin Trials. 2021 Mar;102:106279. PubMed PMID: 33440262

Bryant A, Kalra A, Truesdale A, Pyle L, Martinez-Camacho A. Favorable Sustained Virologic Response Rates Using Direct-Acting Antiviral Therapies at a Large Safety-Net Hospital. J Health Care Poor Underserved. 2020;31(3):1213-1227. PubMed PMID: 33416690

Tommerdahl KL, Baumgartner K, Schäfer M, Bjornstad P, Melena I, Hegemann S, Baumgartner AD, Pyle L, Cree-Green M, Truong U, Browne L, Regensteiner JG, Reusch JEB, Nadeau KJ. Impact of Obesity on Measures of Cardiovascular and Kidney Health in Youth With Type 1 Diabetes as Compared With Youth With Type 2 Diabetes. Diabetes Care. 2021 Mar;44(3):795-803. PubMed PMID: 33402367

Kelsey MM, Severn C, Hilkin AM, Pyle L, Nadeau KJ, Zeitler PS. Puberty Is Associated with a Rising Hemoglobin A1c, Even in Youth with Normal Weight. J Pediatr. 2021 Mar;230:244-247. PubMed PMID: 33300876

Tommerdahl KL, Bjornstad P, Kendrick J, Cree-Green M, Baumgartner AD, Pyle L, Reusch JEB, Nadeau KJ. Results from the Effects of MEtformin on cardiovasculaR function in AdoLescents with type 1 Diabetes (EMERALD) study: A brief report of kidney and inflammatory outcomes. Diabetes Obes Metab. 2021 Mar;23(3):844-849. PubMed PMID: 33236509

Shah VN, Pyle L, Snell-Bergeon JK. Response to Authors' concern. Bone. 2021 Feb;143:115750. PubMed PMID: 33188957

Champakanath A, Keshawarz A, Pyle L, Snell-Bergeon JK, Shah VN. Fracture risk assessment (FRAX) without BMD and risk of major osteoporotic fractures in adults with type 1 diabetes. Bone. 2021 Feb;143:115614. PubMed PMID: 32853853

Forlenza GP, Vigers T, Berget C, Messer LH, Lal RA, Basina M, Maahs DM, Hood K, Buckingham B, Wilson DM, Wadwa RP, Driscoll KA, Pyle L. Predicting success with a first-generation hybrid closed loop artificial pancreas system among children, adolescents, and young adults with type 1 diabetes: a model development and validation study. Diabetes Technology and Therapeutics (in press).

Shah V, Pyle L. Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1. New England Journal of Medicine 2021, 385(e69). DOI: 10.1056/NEJMc2107661.

Breslow E, Taylor A, Severn C, Chan C, Pyle L, Kelsey MM, Cree-Green M. 11-oxyandrogen Concentrations in Adolescents With Polycystic Ovary Syndrome (PCOS). Poster presentation, ENDO 2021 (accepted).

Valentine A, Davis S, Dempsey A, Furniss A, Juarez-Colunga E, Pyle L, Reirden DH, Nokoff NJ. Multicenter analysis of cardiometabolic-related diagnoses in transgender adolescents. Poster presentation, ENDO 2021 (accepted).

Taylor A, Ware M, Breslow E, Pyle L, Severn C, Chan CL, Kelsey MM, Cree-Green M. 11-oxo-androgens in youth with polycystic ovary syndrome. Poster presentation, ENDO 2021 (accepted).

Kelsey MM, Pyle L, Hilkin S, Severn C, Nadeau KJ, Zeitler PS. Adipokines and liver fat predict rising HbA1c during puberty. Poster presentation, Pediatric Endocrine Society 2021.

Stuppy J, Severn C, Parks EJ, Wolfe RR, Carreau AM, Garcia-Reyes Y, Rahat H, Wagner DA, Nadeau KJ, Pyle L, Cree-Green M. Short-term GLP-1 receptor agonist therapy does not influence hepatic de novo lipogenesis in polcystic ovary syndrome. Poster presentation, Experimental Biology 2021 (accepted).

Pyle L, Vigers T, Schauer I, Bergman B, Snell-Bergeon JK. Differential associations between plasma lipids and insulin resistance in women with and without type 1 diabetes. Poster presentation, American Diabetes Association 2021 (accepted).

O’Donnell HK, Vigers T, Alonso GT, Gomer T, Majidi S, Pyle L, Snell-Bergeon J, Sileo D, Wadwa P, Driscoll KA. Support for using objective data from diabetes devices to assess self-management behaviors in adolescents with T1D. Poster presentation, American Diabetes Association 2021 (accepted).

Looker HC, Severn C, Vigers TB, Pyle L, Saulnier P, Najafian B, Mauer M, Nelson RG, Bjornstad P. Youth-onset type 2 diabetes is associated with more severe structural lesions on kidney biopsy than adult-onset type 2 diabetes. Oral presentation, American Diabetes Association.

Mitchell AM, Alkanani A, McDaniel K, Pyle L, Waugh K, Steck A, Nakayama M, Yu L, Gottlieb P, Rewers M, Michels AW. T-cell responses to hybrid insulin peptides precede type 1 diabetes development. Oral presentation, American Diabetes Association 2021.

Cobry E, Karami A, Jost E, Pyle L, Meltzer L, Wadwa RP. Initial impact of the transition to Tandem Control-IQ on sleep in youth with type 1 diabetes and their parents. Poster presentation, ATTD 2021 (accepted).

Maddux AB, Campbell K, Sierra Y, Van KA, Mansour R, Bennett TD, Kerby G, Liptzin DR, Pyle LL, Watson RS, Mourani PM. Pulmonary morbidities are common after pediatric acute respiratory distress syndrome. Poster presentation, American Thoracic Society 2021 (accepted).

Nicklas JM, Leiferman J, Pyle L, Soares A, Bull S, Tong S, Barbour LA. Feasibility of an mHealth Postpartum lifestyle intervention for women with cardiometabolic risk pre- and mid-COVID: the Fit After Baby pilot randomized controlled trial. Oral presentation, Society for General Internal Medicine 2021.

Cobry E, Vigers T, Pyle L, Meltzer LJ. Family exposure and impact of COVID-19 on a pediatric T1D population. Poster presentation, American Diabetes Association 2021.

Karami AJ, Pyle L, Jost E, Wadwa PR, Meltzer LJ, Cobry E. Association of glycemic ranges and sleep measures in youth with type 1 diabetes and their parents. Poster presentation, American Diabetes Association 2021.

Rubio VY, Pyle L, Vigers T, Johnson R, Snell-Bergeon J, Zhang Q. Chemical isotope labeling-based metabolomics to discover cardiovascular disease biomarkers from the Epidemiology of Diabetes Interventions and Complications Study. Poster presentation, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics (accepted).

Tang Y, Pyle L, Vigers T, Johnson R, Snell-Bergeon J, Zhang Q. High-throughput plasma glycated proteome profiling to discover cardiovascular disease biomarkers from the Epidemiology of Diabetes Interventions and Complications Study. Poster presentation, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics (accepted).

Tinsely JP, Carpenter RD, Prakriti J, Pyle LL, Snell-Bergeon S, Shah VN. Femoral neck structure properties are altered in individuals with type 1 diabetes. Poster presentation, American Society for Bone Mineral Research (accepted).

Escobar E, Towers L, Berget C, Vigers T, Pyle L, Messer L, Cobry E, Slover R, Wadwa RP, Driscoll KA, Forlenza GP. Psychosocial impacts of the t:slim X2 pump with Control-IQ technology in a clinical population of youth with type 1 diabetes after 6 months of use. ePoster presentation, International Society for Pediatric and Adolescent Diabetes 2021.

Cobry E, Pyle L, Vigers T, Meltzer L. COVID exposure, impact, and pediatric diabetes quality of life in a population of youth with type 1 diabetes. Poster presentation, International Society for Pediatric and Adolescent Diabetes 2021.

Chan CL, Severn C, Sagel S, Pyle L, Nadeau K. Mechanisms of hypoglycemia during oral glucose tolerance testing in youth with cystic fibrosis. Oral presentation, International Society for Pediatric and Adolescent Diabetes 2021.

Forlenza GP, Vigers T, Berget C, Messer LH, Lal RA, Basina M, Maahs DM, Hood K, Buckingham B, Wilson DM, Wadwa RP, Driscoll KA, Pyle L. Predicting success with a first-generation hybrid closed loop artificial pancreas system among children, adolescents, and young adults with type 1 diabetes: a model development and validation study. ePoster presentation, International Society for Pediatric and Adolescent Diabetes 2021.

Pauley M, Vigers T, Pyle L, Majidi S, Frohnert BI, Simmons KM. Determination of insulin doses in youth with new onset type 1 diabetes. ePoster presentation, International Society for Pediatric and Adolescent Diabetes 2021.

Morelli N, Fordham T, Garcia-Reyes Y, Ware MA, Rahat H, Sundararajan D, Severn C, Pyle L, Parks EJ, Wolfe RR, Cree-Green M. Essential amino acid supplement decreases liver fat in adolescents with PCOS and obesity. Oral presentation, Obesity Week 2021.

Lo JS, Nokoff NJ, Alexander K, D’Alessandro A, Morelli N, Garcia-Reyes Y, Ware M, Rahat H, Severn C, Pyle L, Wolfe RR, Cree-Green M. Effect of essential amino acid supplementation on metabolome and liver fat in adolescents with PCOS. Poster presentation, Obesity Week 2021.

Sundararajan D, Morelli N, Garcia-Reyes Y, Ware M, Rahat H, Sundaram S, Severn C, Pyle L, Cree-Green M. Measuring hepatic steatosis with transient elastography or PCOS-HS score in adolescents with PCOS and obesity. Poster presentation, Obesity Week 2021.

Nevarez J, Thompson T, Pyle L, Ross J, Tartaglia N. Low sensitivity of the Ages & Stages questionnaire in infants with sex chromosome trisomy at 6 and 12 months of age. Oral presentation, Western Medical Research Conference 2022.

Davis S, Nokoff N, Furniss A, Valentine A, Pyle L, Dempsey A. Population-based assessment of cardiometabolic-related diagnoses in youth with Klinefelter syndrome: a PEDSNet study. Oral presentation, Western Medical Research Conference 2022.

Shah VN, Akturk HK, Vigers T, Pyle L, Oliver N, Klonoff DC. Relationship Between Daytime Versus Nighttime Continuous Glucose Monitoring Metrics with A1C in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2023 Jan;25(1):62-68. PubMed PMID: 36306519

Tinsley JP, Carpenter RD, Pyle LL, Snell-Bergeon JK, Sherk VD, Shah VN. Femoral neck structural properties are altered in adults with type 1 diabetes. J Diabetes Complications. 2022 Nov;36(11):108308. PubMed PMID: 36257238

Kravets V, Dwulet JM, Schleicher WE, Hodson DJ, Davis AM, Pyle L, Piscopio RA, Sticco-Ivins M, Benninger RKP. Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response. PLoS Biol. 2022 Sep;20(9):e3001761. PubMed PMID: 36099294

Mitchell AM, Baschal EE, McDaniel KA, Simmons KM, Pyle L, Waugh K, Steck AK, Yu L, Gottlieb PA, Rewers MJ, Nakayama M, Michels AW. Temporal development of T cell receptor repertoires during childhood in health and disease. JCI Insight. 2022 Sep 22;7(18). PubMed PMID: 35998036

Magge SN, Wolf RM, Pyle L, Brown EA, Benavides VC, Bianco ME, Chao LC, Cymbaluk A, Balikcioglu PG, Halpin K, Hsia DS, Huerta-Saenz L, Kim JJ, Kumar S, Levitt Katz LE, Marks BE, Neyman A, O'Sullivan KL, Pillai SS, Shah AS, Shoemaker AH, Siddiqui JAW, Srinivasan S, Thomas IH, Tryggestad JB, Yousif MF, Kelsey MM. The Coronavirus Disease 2019 Pandemic is Associated with a Substantial Rise in Frequency and Severity of Presentation of Youth-Onset Type 2 Diabetes. J Pediatr. 2022 Dec;251:51-59.e2. PubMed PMID: 35985535

Valentine A, Davis S, Furniss A, Dowshen N, Kazak AE, Lewis C, Loeb DF, Nahata L, Pyle L, Schilling LM, Sequeira GM, Nokoff N. Multicenter Analysis of Cardiometabolic-related Diagnoses in Transgender and Gender-Diverse Youth: A PEDSnet Study. J Clin Endocrinol Metab. 2022 Sep 28;107(10):e4004-e4014. PubMed PMID: 35945152

Thompson T, Davis S, Janusz J, Frith E, Pyle L, Howell S, Boada R, Wilson R, Tartaglia N. Supporting students with sex chromosome aneuploidies in educational settings: Results of a nationwide survey. J Sch Psychol. 2022 Aug;93:28-40. PubMed PMID: 35934449

Rewers M, Bonifacio E, Ewald D, Geno Rasmussen C, Jia X, Pyle L, Ziegler AG. SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents From Colorado, USA, and Bavaria, Germany. JAMA. 2022 Sep 27;328(12):1252-1255. PubMed PMID: 35930271

Tayachew B, Vanden Brink H, Garcia-Reyes Y, Rahat H, D'Alessandro A, Frank DN, Robertson CE, Silveira L, Kelsey M, Pyle L, Cree-Green M. Combined Oral Contraceptive Treatment Does Not Alter the Gut Microbiome but Affects Amino Acid Metabolism in Sera of Obese Girls With Polycystic Ovary Syndrome. Front Physiol. 2022;13:887077. PubMed PMID: 35800349

Singh I, Noel G, Barker JM, Chatfield KC, Furniss A, Khanna AD, Nokoff NJ, Patel S, Pyle L, Nahata L, Cole FS, Ikomi C, Bamba V, Fechner PY, Davis SM. Hepatic abnormalities in youth with Turner syndrome. Liver Int. 2022 Oct;42(10):2237-2246. PubMed PMID: 35785515

Messer LH, Vigers T, Pyle L, Fivekiller E, Wadwa RP, Hernandez TL, Cook PF. Novel predictors of daily fluctuations in glycemia and self-management in adolescents and young adults with type 1 diabetes. Diabet Med. 2022 Sep;39(9):e14910. PubMed PMID: 35776655

Taylor AE, Ware MA, Breslow E, Pyle L, Severn C, Nadeau KJ, Chan CL, Kelsey MM, Cree-Green M. 11-Oxyandrogens in Adolescents With Polycystic Ovary Syndrome. J Endocr Soc. 2022 Jul 1;6(7):bvac037. PubMed PMID: 35611324

O'Donnell HK, Vigers T, Johnson SB, Pyle L, Gonder-Fredrick L, Hendrieckx C, Driscoll KA. Bring Blood Glucose Down! An intervention to reduce fear of hypoglycemia in caregivers of adolescents with type 1 diabetes: Study design and participant characteristics. Contemp Clin Trials. 2022 Jul;118:106792. PubMed PMID: 35589025

Melena I, Piani F, Tommerdahl KL, Severn C, Chung LT, MacDonald A, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Cara-Fuentes G, Parikh CR, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis: Results from the diabetic kidney alarm (DKA) study. J Diabetes Complications. 2022 Jun;36(6):108203. PubMed PMID: 35523653

Vigers T, Vinovskis C, Li LP, Prasad P, Heerspink H, D'Alessandro A, Reisz JA, Piani F, Cherney DZ, van Raalte DH, Nadeau KJ, Pavkov ME, Nelson RG, Pyle L, Bjornstad P. Plasma levels of carboxylic acids are markers of early kidney dysfunction in young people with type 1 diabetes. Pediatr Nephrol. 2023 Jan;38(1):193-202. PubMed PMID: 35507146

Vo M, Miller K, Bennett TD, Mourani PM, LaVelle J, Carpenter TC, Scott Watson R, Pyle LL, Maddux AB. Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness. Pediatr Pulmonol. 2022 Jul;57(7):1651-1659. PubMed PMID: 35438830

Shao B, Snell-Bergeon JK, Pyle LL, Thomas KE, de Boer IH, Kothari V, Segrest J, Davidson WS, Bornfeldt KE, Heinecke JW. Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes. J Lipid Res. 2022 Apr;63(4):100196. PubMed PMID: 35300983

Johnson MJ, Tommerdahl KL, Vinovskis C, Waikar S, Reinicke T, Parikh CR, Obeid W, Nelson RG, van Raalte DH, Pyle L, Nadeau KJ, Bjornstad P. Relationship between biomarkers of tubular injury and intrarenal hemodynamic dysfunction in youth with type 1 diabetes. Pediatr Nephrol. 2022 Dec;37(12):3085-3092. PubMed PMID: 35286453

Maddux AB, Mourani PM, Miller K, Carpenter TC, LaVelle J, Pyle LL, Watson RS, Bennett TD. Identifying Long-Term Morbidities and Health Trajectories After Prolonged Mechanical Ventilation in Children Using State All Payer Claims Data. Pediatr Crit Care Med. 2022 Apr 1;23(4):e189-e198. PubMed PMID: 35250002

Rydin AA, Severn C, Pyle L, Dorris K, Chambers C, Stiller D, Hankinson TC, Inge T, Haemer MA, Mirsky DM, Moore J, Kelsey MM. Novel clinical algorithm for hypothalamic obesity in youth with brain tumours and factors associated with excess weight gain. Pediatr Obes. 2022 Jul;17(7):e12903. PubMed PMID: 35224874

Davis SM, Nokoff NJ, Furniss A, Pyle L, Valentine A, Fechner P, Ikomi C, Magnusen B, Nahata L, Vogiatzi MG, Dempsey A. Population-based Assessment of Cardiometabolic-related Diagnoses in Youth With Klinefelter Syndrome: A PEDSnet Study. J Clin Endocrinol Metab. 2022 Apr 19;107(5):e1850-e1859. PubMed PMID: 35106546

Schaub JA, AlAkwaa FM, McCown PJ, Naik AS, Nair V, Eddy S, Menon R, Otto EA, Demeke D, Hartman J, Fermin D, O'Connor C, Subramanian L, Bitzer M, Harned R, Ladd P, Pyle L, Pennathur S, Inoki K, Hodgin JB, Brosius FC, Nelson RG, Kretzler M, Bjornstad P. SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth onset type 2 diabetes. J Clin Invest. 2023 Jan 13. [Epub ahead of print] PubMed PMID: 36637914

Looker HC, Pyle L, Vigers T, Severn C, Saulnier PJ, Najafian B, Mauer M, Nelson RG, Bjornstad P. Structural Lesions on Kidney Biopsy in Youth-Onset and Adult-Onset Type 2 Diabetes. Diabetes Care. 2022 Feb 1;45(2):436-443. PubMed PMID: 35006272

Pauley ME, Vinovskis C, MacDonald A, Baca M, Pyle L, Wadwa RP, Fornoni A, Nadeau KJ, Pavkov M, Nelson RG, Gordin D, de Boer IH, Tommerdahl KL, Bjornstad P. Triglyceride content of lipoprotein subclasses and kidney hemodynamic function and injury in adolescents with type 1 diabetes. J Diabetes Complications. 2022 Dec 13;37(2):108384. [Epub ahead of print] PubMed PMID: 36623423

Navanandan N, Thompson T, Pyle L, Florin TA. Defining Treatment Response for Clinical Trials of Pediatric Acute Asthma. J Allergy Clin Immunol Pract. 2023 Jan 5. [Epub ahead of print] PubMed PMID: 36621607

Sklar J, Pyle L, Snell-Bergeon JK, Garcetti R, Joshee P, Demmitt JK, Polsky S. Glycemic variability and indices of glycemic control among pregnant women with type 1 diabetes (T1D) based on the use of continuous glucose monitoring share technology. J Matern Fetal Neonatal Med. 2022 Dec;35(25):8968-8974. PubMed PMID: 34875947

Akturk HK, Couts KL, Baschal EE, Karakus KE, Van Gulick RJ, Turner JA, Pyle L, Robinson WA, Michels AW. Analysis of Human Leukocyte Antigen DR Alleles, Immune-Related Adverse Events, and Survival Associated With Immune Checkpoint Inhibitor Use Among Patients With Advanced Malignant Melanoma. JAMA Netw Open. 2022 Dec 1;5(12):e2246400. PubMed PMID: 36512357

Cho S, Vigers T, Pyle L, Franklin A, Sopfe J, Jeney F, Forlenza G. Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients. Diabetes Technol Ther. 2022 Dec 29. [Epub ahead of print] PubMed PMID: 36511871

Breslow E, Taylor A, Chan CL, Severn C, Pyle L, Torchen L, Sisk R, Legro R, Turcu AF, Auchus RJ, Duanaif A, Kelsey MM, Cree-Green M. 11-Oxygenated Androgen Metabolite Concentrations are Affected by Pubertal Progression and Obesity. Horm Res Paediatr. 2022 Nov 29. [Epub ahead of print] PubMed PMID: 36446347

Triolo TM, Pyle L, Broncucia H, Armstrong T, Yu L, Gottlieb PA, Steck AK. Association of High-Affinity Autoantibodies With Type 1 Diabetes High-Risk HLA Haplotypes. J Clin Endocrinol Metab. 2022 Mar 24;107(4):e1510-e1517. PubMed PMID: 34850014

Shah VN, Sakamoto C, Pyle L. Optimal Sampling Duration for Continuous Glucose Monitoring for the Estimation of Glycemia Risk Index. Diabetes Technol Ther. 2022 Dec 2. [Epub ahead of print] PubMed PMID: 36399111

Wigglesworth KRS, Vigers T, Pyle L, Youngkin EM, Fay-Itzkowitz E, Tilden J, Raymond JK, Snell-Bergeon J, Sass A, Majidi S. Follow-Up Mental Health Care in Youth and Young Adults With Type 1 Diabetes After Positive Depression Screen and/or Suicidal Ideation. Clin Diabetes. 2022 Fall;40(4):449-457. PubMed PMID: 36385972

Forlenza GP, Vigers T, Berget C, Messer LH, Lal RA, Basina M, Maahs DM, Hood K, Buckingham B, Wilson DM, Wadwa RP, Driscoll KA, Pyle L. Predicting Success with a First-Generation Hybrid Closed-Loop Artificial Pancreas System Among Children, Adolescents, and Young Adults with Type 1 Diabetes: A Model Development and Validation Study. Diabetes Technol Ther. 2022 Mar;24(3):157-166. PubMed PMID: 34780306

Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 Dec;66:101632. PubMed PMID: 36347424

Nunes-Moreno M, Buchanan C, Cole FS, Davis S, Dempsey A, Dowshen N, Furniss A, Kazak AE, Kerlek AJ, Margolis P, Pyle L, Razzaghi H, Reirden DH, Schwartz B, Sequeira GM, Nokoff NJ. Behavioral Health Diagnoses in Youth with Gender Dysphoria Compared with Controls: A PEDSnet Study. J Pediatr. 2022 Feb;241:147-153.e1. PubMed PMID: 34571022

Chan CL, Pyle L, Vigers T, Zeitler PS, Nadeau KJ. The Relationship Between Continuous Glucose Monitoring and OGTT in Youth and Young Adults With Cystic Fibrosis. J Clin Endocrinol Metab. 2022 Jan 18;107(2):e548-e560. PubMed PMID: 34537845

Cobry EC, Reznick-Lipina T, Pyle L, Slover R, Thomas JF, Alonso GT, Wadwa RP. Diabetes Technology Use in Remote Pediatric Patients with Type 1 Diabetes Using Clinic-to-Clinic Telemedicine. Diabetes Technol Ther. 2022 Jan;24(1):67-74. PubMed PMID: 34524007

Akturk HK, Vigers T, Forlenza G, Champakanath A, Pyle L. Comparison of Cgmanalysis, a Free Open-Source Continuous Glucose Monitoring Data Management and Analysis Software, with Commercially Available CGM Platforms: Data Standardization for Diabetes Technology Research. Diabetes Technol Ther. 2022 Jan;24(1):54-60. PubMed PMID: 34524001

Mullin BC, Holzman JBW, Pyle L, Perks EL, Chintaluru Y, Gulley LD, Haraden DA, Hankin BL. Relationships between attention to emotion and anxiety among a community sample of adolescents. Psychol Med. 2022 Jun;52(8):1548-1559. PubMed PMID: 33641686

Cung S, Pyle L, Nadeau K, Dabelea D, Cree-Green M, Davis SM. In-vivo skeletal muscle mitochondrial function in Klinefelter syndrome. J Investig Med. 2022 Jan;70(1):104-107. PubMed PMID: 34493629

Nguyen-Tran H, Thompson C, Butler M, Miller KR, Pyle L, Jung S, Rogers S, Ng TFF, Routh J, Dominguez SR, Messacar K. Duration of Enterovirus D68 RNA Shedding in the Upper Respiratory Tract and Transmission among Household Contacts, Colorado, USA. Emerg Infect Dis. 2023 Nov;29(11):2315-2324. PubMed PMID: 37877582

Wang CS, Sadun RE, Zhou W, Miller KR, Pyle L, Ardoin SP, Bacha C, Hause E, Hui-Yuen J, Ling N, Pereira M, Riebschleger M, Rouster-Stevens K, Sarkissian A, Shalen J, Soulsby W, Twilt M, Wu EY, Lewandowski LB, Wenderfer SE, Cooper JC. Renal Response Outcomes of the EuroLupus and NIH Cyclophosphamide Dosing Regimens in Childhood-Onset Proliferative Lupus Nephritis. Arthritis Rheumatol. 2023 Oct 6. [Epub ahead of print] PubMed PMID: 37800549

Akturk HK, Sakamoto C, Vigers T, Shah VN, Pyle L. Minimum Sampling Duration for Continuous Glucose Monitoring Metrics to Achieve Representative Glycemic Outcomes in Suboptimal Continuous Glucose Monitor Use. J Diabetes Sci Technol. 2023 Sep 25;:19322968231200901. [Epub ahead of print] PubMed PMID: 37747124

Conway RB, Gerard Gonzalez A, Shah VN, Geno Rasmussen C, Akturk HK, Pyle L, Forlenza G, Alonso GT, Snell-Bergeon J. Racial Disparities in Diabetes Technology Adoption and Their Association with HbA1c and Diabetic Ketoacidosis. Diabetes Metab Syndr Obes. 2023;16:2295-2310. PubMed PMID: 37551339

Sen T, Ju W, Nair V, Ladd P, Menon R, Otto EA, Pyle L, Vigers T, Nelson RG, Arnott C, Neal B, Hansen MK, Kretzler M, Bjornstad P, Heerspink HJL. Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes. Kidney Int. 2023 Oct;104(4):828-839. PubMed PMID: 37543256

Huang SD, Bamba V, Bothwell S, Fechner PY, Furniss A, Ikomi C, Nahata L, Nokoff NJ, Pyle L, Seyoum H, Davis SM. Development and Validation of a Computable Phenotype for Turner Syndrome Utilizing Electronic Health Records from a National Pediatric Network. medRxiv. 2023 Jul 23. PubMed PMID: 37502850

Frost HM, Geno Rasmussen C, Shorrosh H, Pyle L, Bautista K, Frohnert BI, Stahl M, Simmons K, Steck AK, Jia X, Yu L, Rewers M. Prevalence of SARS-CoV-2 Antibodies Among Healthy Children From Colorado From 2020 to 2021: A Brief Report. J Prim Care Community Health. 2023 Jan-Dec;14:21501319231189147. PubMed PMID: 37501515

Messer LH, Vigers T, Akturk HK, Forlenza GP, Huss KB, Karami AJ, Malecha E, Oser SM, Polsky S, Pyle L, Shah VN, Wadwa RP, Oser TK. Increasing Use of Diabetes Devices: What Do Health Care Professionals Need?. Clin Diabetes. 2023 Summer;41(3):386-398. PubMed PMID: 37456091

Finn E, Severn C, Pyle L, Garrish J, Vigers T, Behn CGD, Zeitler PS, Sagel SD, Nadeau KJ, Chan CL. Hypoglycemia in children and young adults with cystic fibrosis during oral glucose tolerance testing vs. continuous glucose monitoring. Pediatr Pulmonol. 2023 Sep;58(9):2495-2504. PubMed PMID: 37350354

O'Donnell HK, Trojanowski PJ, Alonso GT, Majidi S, Snell-Bergeon J, Wadwa RP, Vigers T, Pyle L, Gurka MJ, Shaffer E, Driscoll KA. A randomized controlled clinical trial to improve health outcomes in youth with type 1 diabetes: Study design and baseline characteristics. Contemp Clin Trials. 2023 Aug;131:107270. PubMed PMID: 37348599

Corrado MM, Jia X, Geno Rasmussen C, Pyle L, Yu L, Liu E, Stahl M, Rewers MJ. Previous SARS-CoV-2 Infection Is Not Associated With Increased Celiac Disease Autoimmunity in Children and Adolescents. Am J Gastroenterol. 2023 Sep 1;118(9):1698-1700. PubMed PMID: 37159249

Alonso GT, Triolo TM, Akturk HK, Pauley ME, Sobczak M, Forlenza GP, Sakamoto C, Pyle L, Frohnert BI. Increased Technology Use Associated With Lower A1C in a Large Pediatric Clinical Population. Diabetes Care. 2023 Jun 1;46(6):1218-1222. PubMed PMID: 37023293

Jia X, Dong F, Pyle L, Michels AW, Yu L, Rewers M. Similar Time Course of Humoral Response to SARS-CoV-2 mRNA Vaccines in People With and Without Type 1 Diabetes. Diabetes Technol Ther. 2023 Jul;25(7):492-496. PubMed PMID: 36989496

Gutierrez-Colina AM, Bristol M, Clark ELM, Sanchez N, Gulley LD, Ruzicka E, Handing EP, Kinsella E, Kutchman E, Witten M, Clementi MA, Thompson T, Pyle L, Aichele S, Goldschmidt AB, Belcher B, Nadeau KJ, Kelsey MM, Shomaker LB. Cognitive-behavioral therapy and exercise training in adolescent females with elevated depression symptoms and at-risk for type 2 diabetes: Protocol for a randomized controlled trial. Contemp Clin Trials. 2023 May;128:107150. PubMed PMID: 36918091

Shah VN, Vigers T, Pyle L, Calhoun P, Bergenstal RM. Discordance Between Glucose Management Indicator and Glycated Hemoglobin in People Without Diabetes. Diabetes Technol Ther. 2023 May;25(5):324-328. PubMed PMID: 36790875

Schaub JA, AlAkwaa FM, McCown PJ, Naik AS, Nair V, Eddy S, Menon R, Otto EA, Demeke D, Hartman J, Fermin D, O'Connor CL, Subramanian L, Bitzer M, Harned R, Ladd P, Pyle L, Pennathur S, Inoki K, Hodgin JB, Brosius FC 3rd, Nelson RG, Kretzler M, Bjornstad P. SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes. J Clin Invest. 2023 Mar 1;133(5). PubMed PMID: 36637914

Pauley ME, Vinovskis C, MacDonald A, Baca M, Pyle L, Wadwa RP, Fornoni A, Nadeau KJ, Pavkov M, Nelson RG, Gordin D, de Boer IH, Tommerdahl KL, Bjornstad P. Triglyceride content of lipoprotein subclasses and kidney hemodynamic function and injury in adolescents with type 1 diabetes. J Diabetes Complications. 2023 Feb;37(2):108384. PubMed PMID: 36623423

Navanandan N, Thompson T, Pyle L, Florin TA. Defining Treatment Response for Clinical Trials of Pediatric Acute Asthma. J Allergy Clin Immunol Pract. 2023 May;11(5):1450-1458.e1. PubMed PMID: 36621607

Akturk HK, Couts KL, Baschal EE, Karakus KE, Van Gulick RJ, Turner JA, Pyle L, Robinson WA, Michels AW. Analysis of Human Leukocyte Antigen DR Alleles, Immune-Related Adverse Events, and Survival Associated With Immune Checkpoint Inhibitor Use Among Patients With Advanced Malignant Melanoma. JAMA Netw Open. 2022 Dec 1;5(12):e2246400. PubMed PMID: 36512357

Cho S, Vigers T, Pyle L, Franklin A, Sopfe J, Jeney F, Forlenza G. Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients. Diabetes Technol Ther. 2023 Feb;25(2):116-121. PubMed PMID: 36511871

Breslow E, Taylor A, Chan CL, Severn C, Pyle L, Torchen L, Sisk R, Legro R, Turcu AF, Auchus RJ, Dunaif A, Kelsey MM, Cree-Green M. 11-Oxygenated Androgen Metabolite Concentrations Are Affected by Pubertal Progression and Obesity. Horm Res Paediatr. 2023;96(4):412-422. PubMed PMID: 36446347

Shah VN, Sakamoto C, Pyle L. Optimal Sampling Duration for Continuous Glucose Monitoring for the Estimation of Glycemia Risk Index. Diabetes Technol Ther. 2023 Feb;25(2):140-142. PubMed PMID: 36399111

Wigglesworth KRS, Vigers T, Pyle L, Youngkin EM, Fay-Itzkowitz E, Tilden J, Raymond JK, Snell-Bergeon J, Sass A, Majidi S. Follow-Up Mental Health Care in Youth and Young Adults With Type 1 Diabetes After Positive Depression Screen and/or Suicidal Ideation. Clin Diabetes. 2022 Fall;40(4):449-457. PubMed PMID: 36385972

Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 Dec;66:101632. PubMed PMID: 36347424

Shah VN, Akturk HK, Vigers T, Pyle L, Oliver N, Klonoff DC. Relationship Between Daytime Versus Nighttime Continuous Glucose Monitoring Metrics with A1C in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2023 Jan;25(1):62-68. PubMed PMID: 36306519

Professor, Pediatrics-Endocrinology

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