James Feinstein, MD, MPH/MSPH
Associate Professor, Pediatrics-General Pediatrics

Professional Titles

• Attending Physician, Special Care Clinic and Child Health Clinic
• Pediatric Director, Children's Hospital Colorado Epidermolysis Bullosa Program
• Principal Investigator, Adult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS)
• Clinical Research Director, Section of General Academic Pediatrics

Recognition & Awards

• Faculty Professionalism Award, University of Colorado School of Medicine (2022)
  The Faculty Professionalism Award recognizes a full-time School of Medicine faculty member who has served as a role model for professionalism.

Research Interests

Teaching

Publications

• Feinstein JA, Feudtner C, Kempe A, Orth LE. Anticholinergic Medications and Parent-Reported Anticholinergic Symptoms in Neurologically Impaired Children. J Pain Symptom Manage. 2023 Feb;65(2):e109-e114. PubMed PMID: 36332769
• Antoon JW, Hall M, Feinstein JA, Kyler KE, Shah SS, Girdwood ST, Goldman JL, Grijalva CG, Williams DJ. Guideline-Concordant Antiviral Treatment in Children at High Risk for Influenza Complications. Clin Infect Dis. 2023 Feb 8;76(3):e1040-e1046. PubMed PMID: 35867691
• Orth LE, Feudtner C, Kempe A, Morris MA, Colborn KL, Gritz RM, Linnebur SA, Begum A, Feinstein JA. A coordinated approach for managing polypharmacy among children with medical complexity: rationale and design of the Pediatric Medication Therapy Management (pMTM) randomized controlled trial. BMC Health Serv Res. 2023 Apr 29;23(1):414. PubMed PMID: 37120509
• Feinstein JA, Orth LE. Making Polypharmacy Safer for Children with Medical Complexity. J Pediatr. 2023 Mar;254:4-10. PubMed PMID: 36252865
• Nelson KE, Finlay M, Huang E, Chakravarti V, Feinstein JA, Diskin C, Thomson J, Mahant S, Widger K, Feudtner C, Cohen E. Clinical characteristics of children with severe neurologic impairment: A scoping review. J Hosp Med. 2023 Jan;18(1):65-77. PubMed PMID: 36484088
• Kyler KE, Hall M, Antoon JW, Goldman J, Grijalva CG, Shah SS, Tang Girdwood S, Williams DJ, Feinstein JA. Polypharmacy among medicaid-insured children with and without documented obesity. Pharmacotherapy. 2023 Jul;43(7):588-595. PubMed PMID: 36564960
• Sekmen M, Grijalva CG, Zhu Y, Williams DJ, Feinstein JA, Stassun JC, Johnson JA, Tanguturi YC, Gay JC, Antoon JW. Characteristics Associated With Serious Self-Harm Events in Children and Adolescents. Pediatrics. 2023 May 1. [Epub ahead of print] PubMed PMID: 37125480
• Johnson JA, Williams DJ, Feinstein JA, Grijalva CG, Zhu Y, Dickinson E, Stassun JC, Sekmen M, Tanguturi YC, Gay JC, Antoon JW. Positive Predictive Value of ICD-10 Codes to Identify Acute Suicidal and Self Harm Behaviors. Hosp Pediatr. 2023 Aug 1;13(8):e207-e210. PubMed PMID: 37497585
• Feinstein JA, Gill PJ, Anderson BR. Preparing for the International Classification of Diseases, 11th Revision (ICD-11) in the US Health Care System. JAMA Health Forum. 2023 Jul 7;4(7):e232253. PubMed PMID: 37505488
• Scollan ME, Levin LE, Lucky AW, Hook KP, Peoples K, Bruckner AL, Feinstein JA, Pope E, McCuaig CC, Powell J, Eichenfield LF, Levy ML, Diaz L, Glick SA, Paller AS, Browning JC, Morel KD. Characterization of wound microbes in epidermolysis bullosa: A focus on Pseudomonas aeruginosa. Pediatr Dermatol. 2023 Jun 26. [Epub ahead of print] PubMed PMID: 37364926
• Callahan TJ, Stefanski AL, Wyrwa JM, Zeng C, Ostropolets A, Banda JM, Baumgartner WA Jr, Boyce RD, Casiraghi E, Coleman BD, Collins JH, Deakyne Davies SJ, Feinstein JA, Lin AY, Martin B, Matentzoglu NA, Meeker D, Reese J, Sinclair J, Taneja SB, Trinkley KE, Vasilevsky NA, Williams AE, Zhang XA, Denny JC, Ryan PB, Hripcsak G, Bennett TD, Haendel MA, Robinson PN, Hunter LE, Kahn MG. Ontologizing health systems data at scale: making translational discovery a reality. NPJ Digit Med. 2023 May 19;6(1):89. PubMed PMID: 37208468
• Antoon JW, Feinstein JA, Goldman JL, Kyler KE, Shah SS. Advancing pediatric medication safety using real-world data: Current problems and potential solutions. J Hosp Med. 2023 Feb 28. [Epub ahead of print] PubMed PMID: 36855275
• Liy-Wong C, Tarango C, Pope E, Coates T, Bruckner AL, Feinstein JA, Schwieger-Briel A, Hubbard LD, Jane C, Torres-Pradilla M, Zmazek M, Lara-Corrales I. Consensus guidelines for diagnosis and management of anemia in epidermolysis bullosa. Orphanet J Rare Dis. 2023 Feb 23;18(1):38. PubMed PMID: 36823529
• Feinstein JA, Berry JG, Feudtner C. Intervention research to improve care and outcomes for children with medical complexity and their families. Curr Probl Pediatr Adolesc Health Care. 2022 Jan 4;:101126. [Epub ahead of print] PubMed PMID: 34996708
• Bayer ND, Hall M, Li Y, Feinstein JA, Thomson J, Berry JG. Trends in Health Care Use and Spending for Young Children With Neurologic Impairment. Pediatrics. 2022 Jan 1;149(1). PubMed PMID: 34854922
• Nelson KE, Chakravarti V, Diskin C, Thomson J, Cohen E, Mahant S, Feudtner C, Widger K, Pullenayegum E, Berry JG, Feinstein JA. Validation of Neurologic Impairment Diagnosis Codes as Signifying Documented Functional Impairment in Hospitalized Children. Acad Pediatr. 2022 Jul;22(5):782-788. PubMed PMID: 34320414
• Marquez C, Thompson R, Feinstein JA, Orth LE. Identifying opportunities for pediatric medication therapy management in children with medical complexity. J Am Pharm Assoc (2003). 2022 Sep-Oct;62(5):1587-1595.e3. PubMed PMID: 35527209
• Antoon JW, Feinstein JA, Grijalva CG, Zhu Y, Dickinson E, Stassun JC, Johnson JA, Sekmen M, Tanguturi YC, Gay JC, Williams DJ. Identifying Acute Neuropsychiatric Events in Children and Adolescents. Hosp Pediatr. 2022 May 1;12(5):e152-e160. PubMed PMID: 35393609
• Feinstein JA, Bruckner AL, Chastek B, Anderson A, Roman J. Clinical characteristics, healthcare use, and annual costs among patients with dystrophic epidermolysis bullosa. Orphanet J Rare Dis. 2022 Sep 29;17(1):367. PubMed PMID: 36175960
• Nelson KE, Chakravarti V, Diskin C, Thomson J, Cohen E, Mahant S, Feudtner C, Widger K, Pullenayegum E, Berry JG, Feinstein JA. Validation of Neurologic Impairment Diagnosis Codes as Signifying Documented Functional Impairment in Hospitalized Children. Acad Pediatr. 2021 Jul 25. [Epub ahead of print] PubMed PMID: 34320414
• Emdin A, Strzelecki M, Seto W, Feinstein J, Bogler O, Cohen E, Roth DE. Medications Reconciled at Discharge Versus Admission Among Inpatients at a Children's Hospital. Hosp Pediatr. 2021 Dec 1. [Epub ahead of print] PubMed PMID: 34807980
• Thomson J, Hall M, Nelson K, Flores JC, Garrity B, DeCourcey DD, Agrawal R, Goodman DM, Feinstein JA, Coller RJ, Cohen E, Kuo DZ, Antoon JW, Houtrow AJ, Bastianelli L, Berry JG. Timing of Co-occurring Chronic Conditions in Children With Neurologic Impairment. Pediatrics. 2021 Feb;147(2). PubMed PMID: 33414236
• Feinstein JA, Berry JG, Feudtner C. Intervention research to improve care and outcomes for children with medical complexity and their families. Curr Probl Pediatr Adolesc Health Care. 2021 Dec;51(12):101126. PubMed PMID: 34996708
• Feinstein JA, Friedman H, Orth LE, Feudtner C, Kempe A, Samay S, Blackmer AB. Complexity of Medication Regimens for Children With Neurological Impairment. JAMA Netw Open. 2021 Aug 2;4(8):e2122818. PubMed PMID: 34436607
• Blackmer AB, Fox D, Arendt D, Phillips K, Feinstein JA. Perceived Versus Demonstrated Understanding of the Complex Medications of Medically Complex Children. J Pediatr Pharmacol Ther. 2021;26(1):62-72. PubMed PMID: 33424502
• Bettenhausen JL, Hall M, Doupnik SK, Markham JL, Feinstein JA, Berry JG, Gay JC. Hospitalization Outcomes for Rural Children with Mental Health Conditions. J Pediatr. 2021 Feb;229:240-246.e1. PubMed PMID: 33010261
• Markham JL, Hall M, Goldman JL, Bettenhausen JL, Gay JC, Feinstein J, Simmons J, Doupnik SK, Berry JG. Readmissions Following Hospitalization for Infection in Children With or Without Medical Complexity. J Hosp Med. 2021 Mar;16(3):134-141. PubMed PMID: 33617439
• Levin LE, Shayegan LH, Lucky AW, Hook KP, Bruckner AL, Feinstein JA, Whittier S, Lauren CT, Pope E, Lara-Corrales I, Wiss K, McCuaig CC, Powell J, Eichenfield LF, Levy ML, Diaz L, Glick SA, Paller AS, Price HN, Browning JC, Morel KD. Characterization of wound microbes in epidermolysis bullosa: Results from the epidermolysis bullosa clinical characterization and outcomes database. Pediatr Dermatol. 2021 Jan;38(1):119-124. PubMed PMID: 33247481
• Doupnik SK, Rodean J, Feinstein J, Gay JC, Simmons J, Bettenhausen JL, Markham JL, Hall M, Zima BT, Berry JG. Health Care Utilization and Spending for Children With Mental Health Conditions in Medicaid. Acad Pediatr. 2020 Jul;20(5):678-686. PubMed PMID: 32017995
• Feinstein JA, Feudtner C, Blackmer AB, Valuck RJ, Fairclough DL, Holstein J, Gregoire L, Samay S, Kempe A. Parent-Reported Symptoms and Medications Used Among Children With Severe Neurological Impairment. JAMA Netw Open. 2020 Dec 1;3(12):e2029082. PubMed PMID: 33306117
• Feinstein JA, Feudtner C, Valuck RJ, Fairclough DL, Holstein JA, Samay S, Kempe A. Identifying Important Clinical Symptoms in Children With Severe Neurological Impairment Using Parent-Reported Outcomes of Symptoms. JAMA Pediatr. 2020 Nov 1;174(11):1114-1117. PubMed PMID: 33044500
• Horace AE, Golchin N, Knight EMP, Dawson NV, Ma X, Feinstein JA, Johnson HK, Kleinman L, Bakaki PM. A Scoping Review of Medications Studied in Pediatric Polypharmacy Research. Paediatr Drugs. 2020 Feb;22(1):85-94. PubMed PMID: 31823339
• Bettenhausen JL, Hall M, Doupnik SK, Markham JL, Feinstein J, Berry J, Gay JC. Hospitalization Outcomes for Rural Children with Mental Health Conditions. J Pediatr. 2020 Sep 30. [Epub ahead of print] PubMed PMID: 33010261
• Antoon JW, Hall M, Herndon A, Carroll A, Ngo ML, Freundlich KL, Stassun JC, Frost P, Johnson DP, Chokshi SB, Brown CM, Browning WL, Feinstein JA, Grijalva CG, Williams DJ. Prevalence of Clinically Significant Drug-Drug Interactions Across US Children's Hospitals. Pediatrics. 2020 Nov;146(5). PubMed PMID: 33037121
• Thomson JE, Feinstein JA, Hall M, Gay JC, Butts B, Berry JG. Identification of Children With High-Intensity Neurological Impairment. JAMA Pediatr. 2019 Aug 19. [Epub ahead of print] PubMed PMID: 31424541
• Feinstein JA, Rodean J, Hall M, Doupnik SK, Gay JC, Markham JL, Bettenhausen JL, Simmons J, Garrity B, Berry JG. Outpatient Prescription Opioid Use in Pediatric Medicaid Enrollees With Special Health Care Needs. Pediatrics. 2019 Jun;143(6). PubMed PMID: 31138667
• Feinstein JA, Hall M, Antoon JW, Thomson J, Flores JC, Goodman DM, Cohen E, Azuine R, Agrawal R, Houtrow AJ, DeCourcey DD, Kuo DZ, Coller R, Gaur DS, Berry JG. Chronic Medication Use in Children Insured by Medicaid: A Multistate Retrospective Cohort Study. Pediatrics. 2019 Apr;143(4). PubMed PMID: 30914443
• Bogler O, Roth D, Feinstein J, Strzelecki M, Seto W, Cohen E. Choosing medications wisely: Is it time to address paediatric polypharmacy?. Paediatr Child Health. 2019 Aug;24(5):303-305. PubMed PMID: 31379430
• Sabus A, Feinstein J, Romani P, Goldson E, Blackmer A. Management of Self-injurious Behaviors in Children with Neurodevelopmental Disorders: A Pharmacotherapy Overview. Pharmacotherapy. 2019 Jun;39(6):645-664. PubMed PMID: 30793794
• Feinstein JA, Jambal P, Peoples K, Lucky AW, Khuu P, Tang JY, Lara-Corrales I, Pope E, Wiss K, Hook KP, Levin LE, Morel KD, Paller AS, McCuaig CC, Powell J, Eichenfield LF, Price H, Levy ML, Schachner LA, Browning JC, Bayliss S, Jahnke M, Shwayder T, Glick SA, Bruckner AL. Assessment of the Timing of Milestone Clinical Events in Patients With Epidermolysis Bullosa From North America. JAMA Dermatol. 2019 Feb 1;155(2):196-203. PubMed PMID: 30586139
• Golchin N, Johnson H, Bakaki PM, Dawson N, Knight EMP, Meropol SB, Liu R, Feinstein JA, Bolen SD, Kleinman LC, Horace A. Outcome measures in pediatric polypharmacy research: a scoping review. Drugs Ther Perspect. 2019 Sep;35(9):447-458. PubMed PMID: 32256042
• Baker C, Feinstein JA, Ma X, Bolen S, Dawson NV, Golchin N, Horace A, Kleinman LC, Meropol SB, Pestana Knight EM, Winterstein AG, Bakaki PM. Variation of the prevalence of pediatric polypharmacy: A scoping review. Pharmacoepidemiol Drug Saf. 2019 Mar;28(3):275-287. PubMed PMID: 30724414
• Bennett TD, Callahan TJ, Feinstein JA, Ghosh D, Lakhani SA, Spaeder MC, Szefler SJ, Kahn MG. Data Science for Child Health. J Pediatr. 2019 May;208:12-22. PubMed PMID: 30686480
• Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Köhler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN. Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ Digit Med. 2019;2. PubMed PMID: 31119199
• Nelson KE, Feinstein JA, Gerhardt CA, Rosenberg AR, Widger K, Faerber JA, Feudtner C. Emerging Methodologies in Pediatric Palliative Care Research: Six Case Studies. Children (Basel). 2018 Feb 26;5(3). PubMed PMID: 29495384
• Bruckner AL, Fairclough DL, Feinstein JA, Lara-Corrales I, Lucky AW, Tolar J, Pope E. Reliability and validity of the instrument for scoring clinical outcomes of research for epidermolysis bullosa (iscorEB). Br J Dermatol. 2018 May;178(5):1128-1134. PubMed PMID: 29341069
• Feinstein JA, Russell S, DeWitt PE, Feudtner C, Dai D, Bennett TD. R Package for Pediatric Complex Chronic Condition Classification. JAMA Pediatr. 2018 Jun 1;172(6):596-598. PubMed PMID: 29710063
• Anderson BT, Feinstein JA, Kramer RE, Narkewicz MR, Bruckner AL, Brumbaugh DE. Approach and Safety of Esophageal Dilation for Treatment of Strictures in Children With Epidermolysis Bullosa. J Pediatr Gastroenterol Nutr. 2018 Dec;67(6):701-705. PubMed PMID: 30052567
• Bakaki PM, Horace A, Dawson N, Winterstein A, Waldron J, Staley J, Pestana Knight EM, Meropol SB, Liu R, Johnson H, Golchin N, Feinstein JA, Bolen SD, Kleinman LC. Defining pediatric polypharmacy: A scoping review. PLoS One. 2018;13(11):e0208047. PubMed PMID: 30496322
• Gilchrist-Scott DH, Feinstein JA, Agrawal R. Medicaid Managed Care Structures and Care Coordination. Pediatrics. 2017 Sep;140(3). PubMed PMID: 28838950
• Feinstein JA, Morrato EH, Feudtner C. Prioritizing Pediatric Drug Research Using Population-Level Health Data. JAMA Pediatr. 2017 Jan 1;171(1):7-8. PubMed PMID: 27893067
• Smith IM, Corkum PV, Blackmer AB, Feinstein JA. Steps Toward Evidence-Based Management of Sleep Problems in Children with Neurodevelopmental Disorders. Pharmacotherapy. 2016 Jul;36(7):e80-2. PubMed PMID: 27285385
• Dai D, Feinstein JA, Morrison W, Zuppa AF, Feudtner C. Epidemiology of Polypharmacy and Potential Drug-Drug Interactions Among Pediatric Patients in ICUs of U.S. Children's Hospitals. Pediatr Crit Care Med. 2016 May;17(5):e218-28. PubMed PMID: 26959349
• Blackmer AB, Feinstein JA. Management of Sleep Disorders in Children With Neurodevelopmental Disorders: A Review. Pharmacotherapy. 2016 Jan;36(1):84-98. PubMed PMID: 26799351
• Zhong W, Feinstein JA, Patel NS, Dai D, Feudtner C. Tall Man lettering and potential prescription errors: a time series analysis of 42 children's hospitals in the USA over 9 years. BMJ Qual Saf. 2016 Apr;25(4):233-40. PubMed PMID: 26534995
• Feinstein J, Dai D, Zhong W, Freedman J, Feudtner C. Potential Drug-Drug Interactions in Infant, Child, and Adolescent Patients in Children's Hospitals. Pediatrics. 2015 Jan;135(1):e99-e108. PubMed PMID: 25511114
• Brittan MS, Sills MR, Fox D, Campagna EJ, Shmueli D, Feinstein JA, Kempe A. Outpatient follow-up visits and readmission in medically complex children enrolled in Medicaid. J Pediatr. 2015 Apr;166(4):998-1005.e1. PubMed PMID: 25641248
• Sheiko MA, Feinstein JA, Capocelli KE, Kramer RE. The concordance of endoscopic and histologic findings of 1000 pediatric EGDs. Gastrointest Endosc. 2015 Jun;81(6):1385-91. PubMed PMID: 25440693
• Feinstein JA, Feudtner C, Valuck RJ, Kempe A. The depth, duration, and degree of outpatient pediatric polypharmacy in Colorado fee-for-service Medicaid patients. Pharmacoepidemiol Drug Saf. 2015 Oct;24(10):1049-57. PubMed PMID: 26248529
• Zhong W, Feinstein JA, Patel NS, Dai D, Feudtner C. Tall Man lettering and potential prescription errors: a time series analysis of 42 children's hospitals in the USA over 9 years. BMJ Qual Saf. 2015 Nov 3. [Epub ahead of print] PubMed PMID: 26534995
• Feinstein JA, Feudtner C, Kempe A. Adverse drug event-related emergency department visits associated with complex chronic conditions. Pediatrics. 2014 Jun;133(6):e1575-85. PubMed PMID: 24843054
• Feudtner C, Feinstein JA, Zhong W, Hall M, Dai D. Pediatric complex chronic conditions classification system version 2: updated for ICD-10 and complex medical technology dependence and transplantation. BMC Pediatr. 2014 Aug 8;14:199. PubMed PMID: 25102958
• Sheiko MA, Feinstein JA, Capocelli KE, Kramer RE. The concordance of endoscopic and histologic findings of 1000 pediatric EGDs. Gastrointest Endosc. 2014 Nov 1. [Epub ahead of print] PubMed PMID: 25440693
• Sheiko MA, Feinstein JA, Capocelli KE, Kramer RE. Diagnostic yield of EGD in children: a retrospective single-center study of 1000 cases. Gastrointest Endosc. 2013 Jul;78(1):47-54.e1. PubMed PMID: 23669024
• Feinstein JA. Amigos. Arch Pediatr Adolesc Med. 2011 Oct;165(10):879. PubMed PMID: 21969388
• Tubbs-Cooley HL, Santucci G, Kang TI, Feinstein JA, Hexem KR, Feudtner C. Pediatric nurses' individual and group assessments of palliative, end-of-life, and bereavement care. J Palliat Med. 2011 May;14(5):631-7. PubMed PMID: 21476885
• Feinstein JA, Cain WT. Comfort amidst the chaos. Med Econ. 2010 Jan 8;87(1):14-6. PubMed PMID: 20196310
• Feudtner C, Hexem KR, Shabbout M, Feinstein JA, Sochalski J, Silber JH. Prediction of pediatric death in the year after hospitalization: a population-level retrospective cohort study. J Palliat Med. 2009 Feb;12(2):160-9. PubMed PMID: 19207060
• Feinstein JA. Three's company. Arch Pediatr Adolesc Med. 2009 Sep;163(9):782. PubMed PMID: 19736329
• Bair-Merritt MH, Feudtner C, Localio AR, Feinstein JA, Rubin D, Holmes WC. Health care use of children whose female caregivers have intimate partner violence histories. Arch Pediatr Adolesc Med. 2008 Feb;162(2):134-9. PubMed PMID: 18250237
• Feinstein JA. Death, quietly?. Acad Med. 2007 Feb;82(2):183. PubMed PMID: 17264698
• Feudtner C, Santucci G, Feinstein JA, Snyder CR, Rourke MT, Kang TI. Hopeful thinking and level of comfort regarding providing pediatric palliative care: a survey of hospital nurses. Pediatrics. 2007 Jan;119(1):e186-92. PubMed PMID: 17200243
• Feudtner C, Feinstein JA, Satchell M, Zhao H, Kang TI. Shifting place of death among children with complex chronic conditions in the United States, 1989-2003. JAMA. 2007 Jun 27;297(24):2725-32. PubMed PMID: 17595273
• Weiss PF, Feinstein JA, Luan X, Burnham JM, Feudtner C. Effects of corticosteroid on Henoch-Schönlein purpura: a systematic review. Pediatrics. 2007 Nov;120(5):1079-87. PubMed PMID: 17974746
• Feinstein JA, Ernst LM, Ganesh J, Feudtner C. What new information pediatric autopsies can provide: a retrospective evaluation of 100 consecutive autopsies using family-centered criteria. Arch Pediatr Adolesc Med. 2007 Dec;161(12):1190-6. PubMed PMID: 18056565
• Feinstein JA. Teaching and learning moments: Anaphylactic shock. Acad Med. 2005 Dec;80(12):1113. PubMed PMID: 16306283
• Feinstein JA. Setting sights. Arch Pediatr Adolesc Med. 2005 Dec;159(12):1101. PubMed PMID: 16330730
• Feinstein JA. A bag of humility. J Gen Intern Med. 2005 Nov;20(11):1075-6. PubMed PMID: 16307639

Professional Memberships

• American Academy of Pediatrics, Fellow
• Alpha Omega Alpha (UPenn Chapter), Elected Member
• Pediatrics, Member, Editorial Board
• New England Journal of Medicine Journal Watch Pediatrics & Adolescent Medicine, Associate Editor
• State of Colorado Medicaid Pharmacy & Therapeutics Committee, Elected Member