Taizo Nakano, MD

Associate Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation


FacultyPhoto
Medical School
  • MD, Albert Einstein College of Medicine of Yeshiva University (2006)
Undergraduate School
  • BS, University of California–Los Angeles (CA) (2002)
Residency
  • Children's Hospital-Oakland Program, Pediatrics (2009)
Fellowships
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Hematology / Oncology (2013)
Languages
English
Department
Pediatrics-Heme/Onc and Bone Marrow Transplantation

Professional Titles

  • Medical Director, Vascular Anomalies Center

Publications

  • Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE. Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8272-7. PubMed PMID: 27307436
  • Massive fetal chylothorax successfully treated with postnatal talc pleurodesis: A case report and review of the literature Maggie M. Hodges, Timothy M. Crombleholme, Mariana Meyers, Ann Kulungowski, Ahmed I. Marwan, Taizo Nakano, Nicholas Behrendt, Kenneth W. Liechty Journal of Pediatric Surgery Case Reports, Vol. 9, p1–4 Published online: March 29, 2016
  • Trauma Induced Coaulopathy Chapter 16: Platelet Aggregometry Taizo Nakano and Jorge Di Paola Springer 2016
  • Nakano T, Zeinati C. Venous Thromboembolism in Pediatric Vascular Anomalies. Frontiers in Pediatrics. 2017
  • Dahl NA, Chatfield K, Kulungowski AM, Harned R, Nakano TA. Unique considerations in the pediatric diagnosis of hereditary hemorrhagic telangiectasia. Annals of Vascular Medicine and Research, 2016;3(4):1042
  • 7. Nakano T, Zeinati C. Venous Thromboembolism in Pediatric Vascular Anomalies. Frontiers in Pediatrics. 2017
  • 8. Chellapandian D, Hines M, Zhang R, Jeng M, Van den Bos C, Santa-Maria V, Lehmberg, K, Sieni, E, Wang Y, Nakano, T, et al. A multicenter study on patients with multisystem Langerhans cell histiocytosis developing secondary hemophagocytic lymphohistiocytosis. Cancer 2018.
  • 3. Nakano T, Di Paola J. Bone Marrow Failure: Inherited Thrombocytopenia. Springer 2018
  • Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A. Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study. Haematologica. 2019 Oct;104(10):1974-1983. PubMed PMID: 30948484
  • Madsen HJ, Annam A, Harned R, Nakano TA, Larroque LO, Kulungowski AM. Symptom Resolution and Volumetric Reduction of Abdominal Lymphatic Malformations With Sclerotherapy. J Surg Res. 2019 Jan;233:256-261. PubMed PMID: 30502256
  • Nakano TA, Lau BW, Dickerson KE, et al. Diagnosis and Treatment of Pediatric Myelodysplastic Syndromes: A Survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatric Blood and Cancer 2020.
  • Kemme S, Brigham D, Feldman A, Nakano TA et al. Outcomes of Severe Seronegative Hepatitis-Associated Aplastic Anemia: A Pediatric Case Series. Journal of Pediatric Gastroenterology & Nutrition 2020.
  • Pulsipher MA, Lehmann LE, Bertuch AA, Sasa G, Olson TS, Nakano TA et al. A study assessing the feasibility of randomization of pediatric and young adult patients between matched unrelated donor bone marrow transplantation and immune-suppressive therapy for newly diagnosed severe aplastic anemia: a joint pilot trial of the North American Pediatric Aplastic Anemia Consortium and the Pediatric Transplantation and Cellular Therapy Consortium. Pediatric Blood & Cancer 2020
  • Kennedy AL, Myers KC, Bowman J, Nakano TA et al. Distinct genetic pathways define pre-leukemic and compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. bioRXiv 2020.
  • PMID: 34570941 DOI: 10.1002/jgc4.1510
  • PMID: 31879230 PMCID: PMC7984274 DOI: 10.1016/S2352-3026(19)30206-6
  • Borst AJ, Nakano TA, Blei F, Adams D, Duis J. A Primer on the Genetic Approach to Vascular Anomalies. Frontiers in Pediatrics. September 2020 doi: 10.3389/fped.2020.579591
  • Betensky M, Mosha M, Tarango C, Verma A, Bhat R, Kucine N, Nakano TA, Nakar C, Woods G, Amankwah E, Brandão LR, Schulman S, Goldenberg NA. Outcomes in Children with Provoked Venous Thrombosis and Antiphospholipid Antibodies: Findings from the Kids-DOTT Trial. Blood Adv. 2024 Sep 25. [Epub ahead of print] PubMed PMID: 39321425
  • Chandrakasan S, Allen CE, Bhatla D, Carter J, Chien M, Cooper R, Draper L, Eckstein OS, Hanna R, Hays JA, Hermiston ML, Hinson AP, Hobday PM, Isakoff MS, Jordan MB, Leiding JW, Modica R, Nakano TA, Oladapo A, Patel SA, Pednekar P, Riskalla M, Sarangi SN, Satwani P, Tandra A, Walkovich KJ, Yee JD, Zoref-Lorenz A, Behrens EM. Emapalumab Use in Patients With Rheumatologic Disease-Associated Hemophagocytic Lymphohistiocytosis in the United States: the REAL-HLH Study. Arthritis Rheumatol. 2024 Sep 8. [Epub ahead of print] PubMed PMID: 39245963
  • Kim TO, Geris JM Dr, Flanagan JM, Grace RF, Lambert MP, O'Farrell C, Rose MJ, Shimano KA, Niss O, Neunert CE, Nakano TA, MacMath D, Dinu B, Kirk SE, Neufeld EJ, Despotovic JM, Scheurer ME, Grimes AB. Genetic Variants in Canonical Wnt Signaling Pathway Associated with Pediatric Immune Thrombocytopenia. Blood Adv. 2024 Aug 27. [Epub ahead of print] PubMed PMID: 39189922
  • Nakano TA, Grimes AB, Klaassen RJ, Lambert MP, Neunert C, Rothman JA, Shimano KA, Amend C, Askew M, Badawy SM, Baker JM, Breakey V, Crary S, Davini M, Fritch Lilla S, Gilbert M, Hays T, Hege K, Hillier K, Jacobson-Kelly A, Kaicker S, Kim TO, Kochhar M, Leblanc T, Martinelli M, Nunez M, Remiker A, Schultz C, Sharma R, Grace RF. What is in a name: defining pediatric refractory ITP. Blood Adv. 2024 Oct 8;8(19):5112-5117. PubMed PMID: 39059013
  • Wang YM, Kaj-Carbaidwala B, Lane A, Agarwal S, Beier F, Bertuch A, Borovsky KA, Brennan SK, Calado RT, Catto LFB, Dufour C, Ebens CL, Fioredda F, Giri N, Gloude N, Goldman F, Hertel PM, Himes R, Keel SB, Koura DT, Kratz CP, Kulkarni S, Liou I, Nakano TA, Nastasio S, Niewisch MR, Penrice DD, Sasa GS, Savage SA, Simonetto DA, Ziegler DS, Miethke AG, Myers KC. Liver disease and transplantation in telomere biology disorders: An international multicenter cohort. Hepatol Commun. 2024 Jul 1;8(7). PubMed PMID: 38896081
  • Shimano KA, Sasa G, Broglie L, Gloude NJ, Myers K, Nakano TA, Sharathkumar A, Rothman JA, Pereda MA, Overholt K, Narla A, McGuinn C, Lau BW, Geddis AE, Dror Y, de Jong JLO, Castillo P, Allen SW, Boklan J. Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer. 2024 Aug;71(8):e31075. PubMed PMID: 38764170
  • Shimano KA, Rothman JA, Allen SW, Castillo P, de Jong JLO, Dror Y, Geddis AE, Lau BW, McGuinn C, Narla A, Overholt K, Pereda MA, Sharathkumar A, Sasa G, Nakano TA, Myers K, Gloude NJ, Broglie L, Boklan J. Treatment of newly diagnosed severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer. 2024 Aug;71(8):e31070. PubMed PMID: 38757488
  • Borst AJ, Eng W, Griffin M, Ricci KW, Engel E, Adams DM, Dayneka J, Cohen-Cutler SJ, Andreoli SM, Wu MD, Wheeler AP, Heym KM, Crary SE, Nakano TA, Schulte RR, Setty BA, McLean TW, Pahl KS, Intzes S, Pateva I, Teitelbaum M, Zong Z, Li Y, Jeng MR. Treatment practices and response in kaposiform hemangioendothelioma: A multicenter cohort study. Pediatr Blood Cancer. 2024 Mar;71(3):e30779. PubMed PMID: 38073018
  • Sheppard SE, March ME, Seiler C, Matsuoka LS, Kim SE, Kao C, Rubin AI, Battig MR, Khalek N, Schindewolf E, O'Connor N, Pinto E, Priestley JR, Sanders VR, Niazi R, Ganguly A, Hou C, Slater D, Frieden IJ, Huynh T, Shieh JT, Krantz ID, Guerrero JC, Surrey LF, Biko DM, Laje P, Castelo-Soccio L, Nakano TA, Snyder K, Smith CL, Li D, Dori Y, Hakonarson H. Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition. JCI Insight. 2023 May 8;8(9). PubMed PMID: 37154160
  • Lozano Chinga MM, Bertuch AA, Afify Z, Dollerschell K, Hsu JI, John TD, Rao ES, Rowe RG, Sankaran VG, Shimamura A, Williams DA, Nakano TA. Expanded phenotypic and hematologic abnormalities beyond bone marrow failure in MECOM-associated syndromes. Am J Med Genet A. 2023 Jul;191(7):1826-1835. PubMed PMID: 37067177

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
  • UCHealth Memorial Hospital

Specialty Information

Specialties
  • Pediatrics, Board Certification (2009)
  • Pediatric Hematology / Oncology, Board Certification (2015)
Conditions & Treatments
  • Blood / Lymphatic System - Clotting Disorders
  • Blood / Lymphatic System
  • Blood / Lymphatic System - Bleeding Disorders
  • Blood / Lymphatic System - Blood Disorders
  • Cancers - Aplastic Anemia
  • Cancers
  • Cancers - Blood and Marrow Transplant
  • Cancers - Chemotherapy
  • Cancers - Leukemia (Childhood)
  • Immune System - Immunodeficiency
  • Immune System
  • Hereditary Hemorrhagic Telangiectasia (HHT)
  • Critical Care
Clinical Interests
My many clinical interests include general hematology, specifically inherited and acquired bone marrow failure syndromes, immune thrombocytopenia, inherited and acquired hemolytic anemias, iron metabolism, disorders of bleeding and clotting, and vascular birthmarks, malformations and tumors

Care Philosophy
Welcome to our family. We'll work towards answers, understanding and a personalized care plan together.

Personal Interests
Music provides inspiration in my life and my medical practice. From a concert crowd, to spontaneous karaoke with my children, to the middle of the outpatient clinic, expect both song and dance.