American Cancer Society Clinician Scientist Development Award, ACS
(2020)
American Society of Clinical Oncology Young Investigator Award, ASCO
(2013)
Hartford Scholar, The Hartford Foundation
(2013)
Research Interests
My research mainly focuses on
- improving the treatment options available to patients with advanced genitourinary cancers
- delivering goal-concordant care to all older adults facing advanced cancer.
- designing clinical trials and delivering care in a manner that increases the inclusion of older adults
Publications
Lum HD, Ressalam J, Kini V, Kessler ER, DeCamp M, Kutner JS, Campbell EG. Use and Influence of Medical Aid in Dying Service on Physician Experiences. J Palliat Med. 2023 Jan;26(1):110-113. PubMed PMID: 36409540
Campbell EG, Kini V, Ressalam J, Mosley BS, Bolcic-Jankovic D, Lum HD, Kessler ER, DeCamp M. Physicians' Attitudes and Experiences with Medical Aid in Dying in Colorado: a "Hidden Population" Survey. J Gen Intern Med. 2022 Jan 11. [Epub ahead of print] PubMed PMID: 35018562
Bourlon MT, Verduzco-Aguirre H, Molina E, Meyer E, Kessler E, Kim SP, Spiess PE, Flaig T. Patterns of Treatment and Outcomes in Older Men With Penile Cancer: A SEER Dataset Analysis. Front Oncol. 2022;12:926692. PubMed PMID: 35847850
Motzer RJ, Powles T, Burotto M, Escudier B, Bourlon MT, Shah AY, Suárez C, Hamzaj A, Porta C, Hocking CM, Kessler ER, Gurney H, Tomita Y, Bedke J, Zhang J, Simsek B, Scheffold C, Apolo AB, Choueiri TK. Nivolumab plus cabozantinib versus sunitinib in first-line treatment for advanced renal cell carcinoma (CheckMate 9ER): long-term follow-up results from an open-label, randomised, phase 3 trial. Lancet Oncol. 2022 Jul;23(7):888-898. PubMed PMID: 35688173
Kini V, Mosley B, Ressalam J, Bolcic-Jankovic D, Lum HD, Kessler ER, DeCamp M, Campbell EG. A novel methodology to identify and survey physicians participating in medical aid-in-dying. Sci Rep. 2022 Apr 11;12(1):6056. PubMed PMID: 35410431
Langlais CS, Chen YH, Van Blarigan EL, Kenfield SA, Kessler ER, Daniel K, Ramsdill JW, Beer TM, Graff RE, Paich K, Chan JM, Winters-Stone KM. Quality of Life of Prostate Cancer Survivors Participating in a Remotely Delivered Web-Based Behavioral Intervention Pilot Randomized Trial. Integr Cancer Ther. 2022 Jan-Dec;21:15347354211063500. PubMed PMID: 35389288
Jordan SR, Geiger CL, Fischer SM, Kessler ER. Care planning priorities of older patients with advanced bladder cancer. J Geriatr Oncol. 2022 May;13(4):432-439. PubMed PMID: 35123920
Campbell EG, Kini V, Ressalam J, Mosley BS, Bolcic-Jankovic D, Lum HD, Kessler ER, DeCamp M. Physicians' Attitudes and Experiences with Medical Aid in Dying in Colorado: a "Hidden Population" Survey. J Gen Intern Med. 2022 Oct;37(13):3310-3317. PubMed PMID: 35018562
Kessler ER, Schmiege SJ, Eguchi M, Singh S, Fischer SM. "Patterns of treatment in older patients with newly diagnosed advanced bladder cancer: a SEER dataset analysis" Aging and Cancer. 2022
Dotan E, Walter LC, Browner IS, Clifton K, Cohen HJ, Extermann M, Gross C, Gupta S, Hollis G, Hubbard J, Jagsi R, Keating NL, Kessler E, Koll T, Korc-Grodzicki B, McKoy JM, Misra S, Moon D, O'Connor T, Owusu C, Rosko A, Russell M, Sedrak M, Siddiqui F, Stella A, Stirewalt DL, Subbiah IM, Tew WP, Williams GR, Hollinger L, George GV, Sundar H. NCCN Guidelines® Insights: Older Adult Oncology, Version 1.2021. J Natl Compr Canc Netw. 2021 Sep 20;19(9):1006-1019. PubMed PMID: 34551388
Robin TP, Geiger CL, Callihan EB, Kessler ER. Prostate Cancer in Older Adults: Risk of Clinically Meaningful Disease, the Role of Screening and Special Considerations. Curr Oncol Rep. 2021 Aug 27;23(11):130. PubMed PMID: 34453258
Rodrigues Pessoa R, Morrison JC, Konety B, Gershman B, Maroni P, Kukreja JB, Cost N, Flaig T, Kessler E, Sharma P, Kim SP. National trends in clinical and pathologic staging for upper tract urothelial carcinoma: Implications for neoadjuvant chemotherapy. Urol Oncol. 2021 Dec;39(12):832.e9-832.e15. PubMed PMID: 33820697
Choueiri TK, Powles T, Burotto M, Escudier B, Bourlon MT, Zurawski B, Oyervides Juárez VM, Hsieh JJ, Basso U, Shah AY, Suárez C, Hamzaj A, Goh JC, Barrios C, Richardet M, Porta C, Kowalyszyn R, Feregrino JP, Zolnierek J, Pook D, Kessler ER, Tomita Y, Mizuno R, Bedke J, Zhang J, Maurer MA, Simsek B, Ejzykowicz F, Schwab GM, Apolo AB, Motzer RJ. Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma. N Engl J Med. 2021 Mar 4;384(9):829-841. PubMed PMID: 33657295
Boxley PJ, Smith DE, Gao D, Kessler ER, Echalier B, Bernard B, Ormond DR, Lam ET, Kavanagh BD, Flaig TW. Prostate Cancer Central Nervous System Metastasis in a Contemporary Cohort. Clin Genitourin Cancer. 2021 Jun;19(3):217-222.e1. PubMed PMID: 33069585
Margulis V, Puligandla M, Trabulsi EJ, Plimack ER, Kessler ER, Matin SF, Godoy G, Alva A, Hahn NM, Carducci MA, Hoffman-Censits J. Reply by Authors. J Urol. 2020 Jan 22;:101097JU000000000000064402. [Epub ahead of print] PubMed PMID: 31967495
Chan JM, Van Blarigan EL, Langlais CS, Zhao S, Ramsdill JW, Daniel K, Macaire G, Wang E, Paich K, Kessler ER, Beer TM, Lyons KS, Broering JM, Carroll PR, Kenfield SA, Winters-Stone KM. Feasibility and Acceptability of a Remotely Delivered, Web-Based Behavioral Intervention for Men With Prostate Cancer: Four-Arm Randomized Controlled Pilot Trial. J Med Internet Res. 2020 Dec 31;22(12):e19238. PubMed PMID: 33382378
Wang EY, Graff RE, Chan JM, Langlais CS, Broering JM, Ramsdill JW, Kessler ER, Winters-Stone KM, Van Blarigan EL, Kenfield SA. Web-Based Lifestyle Interventions for Prostate Cancer Survivors: Qualitative Study. JMIR Cancer. 2020 Nov 10;6(2):e19362. PubMed PMID: 33170126
Boxley PJ, Smith DE, Gao D, Kessler ER, Echalier B, Bernard B, Ormond DR, Lam ET, Kavanagh BD, Flaig TW. Prostate Cancer Central Nervous System Metastasis in a Contemporary Cohort. Clin Genitourin Cancer. 2020 Aug 22. [Epub ahead of print] PubMed PMID: 33069585
Kessler ER, Kukreja JB, Geiger CL, Fischer SM. Treating Elderly Patients With Muscle-Invasive Bladder Cancer. J Natl Compr Canc Netw. 2020 Jun;18(6):783-790. PubMed PMID: 32502977
Hsu T, Kessler ER, Parker IR, Dale W, Gajra A, Holmes HM, Maggiore RJ, Magnuson A, McKoy JM, Hurria A. Identifying Geriatric Oncology Competencies for Medical Oncology Trainees: A Modified Delphi Consensus Study. Oncologist. 2020 Jul;25(7):591-597. PubMed PMID: 32237179
Margulis V, Puligandla M, Trabulsi EJ, Plimack ER, Kessler ER, Matin SF, Godoy G, Alva A, Hahn NM, Carducci MA, Hoffman-Censits J. Reply by Authors. J Urol. 2020 Apr;203(4):697-698. PubMed PMID: 31967495
Margulis V, Puligandla M, Trabulsi EJ, Plimack ER, Kessler ER, Matin SF, Godoy G, Alva A, Hahn NM, Carducci MA, Hoffman-Censits J. Phase II Trial of Neoadjuvant Systemic Chemotherapy Followed by Extirpative Surgery in Patients with High Grade Upper Tract Urothelial Carcinoma. J Urol. 2020 Apr;203(4):690-698. PubMed PMID: 31702432
Margulis V, Puligandla M, Trabulsi EJ, Plimack ER, Kessler ER, Matin SF, Godoy G, Alva A, Hahn NM, Carducci MA, Hoffman-Censits J. Phase II Trial of Neoadjuvant Systemic Chemotherapy Followed by Extirpative Surgery in Patients with High Grade Upper Tract Urothelial Carcinoma. J Urol. 2019 Nov 8;:101097JU0000000000000644. [Epub ahead of print] PubMed PMID: 31702432
Hahn AW, Stenehjem DD, Alex AB, Gill DM, Cheng HH, Kessler ER, Chittoria N, Twardowski P, Vaishampayan U, Agarwal N. Time from definitive therapy to onset of metastatic disease predicts outcomes in men with metastatic hormone sensitive prostate cancer. Urol Oncol. 2019 Jun;37(6):352.e19-352.e24. PubMed PMID: 30770300
Duarte C, Jimeno A, Kessler ER. Abiraterone acetate to treat metastatic castration-resistant prostate cancer in combination with prednisone. Drugs Today (Barc). 2019 Jan;55(1):5-15. PubMed PMID: 30740608
Walker JP, Saltzman AF, Kessler ER, Cost NG. Adult Wilms Tumor During Pregnancy: Case Report and Literature Review. Urology. 2019 Jul;129:200-205. PubMed PMID: 30597169
Kessler ER, Gao D, Flaig TW, Breaker K, Wold M, Wacker M, Lam ET. Phase II study of cabazitaxel with or without abiraterone acetate and prednisone in patients with metastatic castrate resistant prostate cancer after prior docetaxel and abiraterone acetate. Ann Oncol. 2017 Feb 14. [Epub ahead of print] PubMed PMID: 28203770
Stokes W, Amini A, Maroni PD, Kessler ER, Stokes C, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Patterns of care and survival outcomes for adolescent and young adult patients with testicular seminoma in the United States: A National Cancer Database analysis. J Pediatr Urol. 2017 Jan 17. [Epub ahead of print] PubMed PMID: 28153774
Neuwelt AJ, Mathur S, Johnson AT, Kessler ER, Bowles DW. Cabozantinib use in renal cell carcinoma. Drugs Today (Barc). 2017 May;53(5):299-307. PubMed PMID: 28650002
Kessler ER, Gao D, Flaig TW, Breaker K, Wold M, Wacker M, Lam ET. Phase II study of cabazitaxel with or without abiraterone acetate and prednisone in patients with metastatic castrate resistant prostate cancer after prior docetaxel and abiraterone acetate. Ann Oncol. 2017 Mar 1;28(3):668. PubMed PMID: 28426121
Amini A, Raben D, Crawford ED, Flaig TW, Kessler ER, Lam ET, Maroni P, Pugh TJ. Patient characterization and usage trends of proton beam therapy for localized prostate cancer in the United States: A study of the National Cancer Database. Urol Oncol. 2017 Jun;35(6):438-446. PubMed PMID: 28214281
Stokes W, Amini A, Maroni PD, Kessler ER, Stokes C, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Patterns of care and survival outcomes for adolescent and young adult patients with testicular seminoma in the United States: A National Cancer Database analysis. J Pediatr Urol. 2017 Aug;13(4):386.e1-386.e7. PubMed PMID: 28153774
Kessler ER. What is behind the flare phenomenon?. BJU Int. 2016 Dec;118(6):845-846. PubMed PMID: 27870361
Loh KP, Mohile SG, Kessler E, Fung C. Treatment of Metastatic Prostate Cancer in Older Adults. Curr Oncol Rep. 2016 Oct;18(10):63. PubMed PMID: 27586377
Amini A, Waxweiler TV, Maroni PD, Kessler ER, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Survival outcomes of adolescent and adult patients with non-seminomatous testicular germ-cell tumors: A population-based study. J Pediatr Urol. 2016 Dec;12(6):405.e1-405.e9. PubMed PMID: 27544905
Kessler ER, Eckhardt SG, Pitts TM, Bradshaw-Pierce EL, O'byrant CL, Messersmith WA, Nallapreddy S, Weekes C, Spratlin J, Lieu CH, Kane MA, Eppers S, Freas E, Leong S. Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers. Invest New Drugs. 2016 Apr;34(2):176-83. PubMed PMID: 26715573
Kessler E. Capsule commentary on tomko et Al., a comparison of web- versus print-based decision AIDS for prostate cancer screening: participants' evaluation and utilization. J Gen Intern Med. 2015 Jan;30(1):94. PubMed PMID: 25266409
Kessler ER, Eckhardt SG, Pitts TM, Bradshaw-Pierce EL, O'byrant CL, Messersmith WA, Nallapreddy S, Weekes C, Spratlin J, Lieu CH, Kane MA, Eppers S, Freas E, Leong S. Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers. Invest New Drugs. 2015 Dec 30. [Epub ahead of print] PubMed PMID: 26715573
Altoos B, Amini A, Yacoub M, Bourlon MT, Kessler EE, Flaig TW, Fisher CM, Kavanagh BD, Lam ET, Karam SD. Local Control Rates of Metastatic Renal Cell Carcinoma (RCC) to Thoracic, Abdominal, and Soft Tissue Lesions Using Stereotactic Body Radiotherapy (SBRT). Radiat Oncol. 2015 Oct 28;10:218. PubMed PMID: 26510665
Amini A, Altoos B, Bourlon MT, Bedrick E, Bhatia S, Kessler ER, Flaig TW, Fisher CM, Kavanagh BD, Lam ET, Karam SD. Local control rates of metastatic renal cell carcinoma (RCC) to the bone using stereotactic body radiation therapy: Is RCC truly radioresistant?. Pract Radiat Oncol. 2015 Nov-Dec;5(6):e589-96. PubMed PMID: 26142027
Kessler ER, Amini A, Wilson SS, Anp-C KB, Raben D, La Rosa FG, Crawford ED. Lymphoepithelioma-Like Carcinoma of the Urinary Bladder. Oncology (Williston Park). 2015 Jun;29(6):462, C3. PubMed PMID: 26089221
Kessler E. Capsule commentary on Tomko et al., A comparison of web- versus print-based decision AIDS for prostate cancer screening: participants' evaluation and utilization. J Gen Intern Med. 2015 Jan;30(1):94. PubMed PMID: 25266409
Kessler ER, Moss A, Eckhardt SG, Laudenslager ML, Kilbourn K, Mauss IB, Bowles DW, Hecker S, Fairclough DL, Kutner JS. Distress among caregivers of phase I trial participants: a cross-sectional study. Support Care Cancer. 2014 Dec;22(12):3331-40. PubMed PMID: 25120010
Kessler ER, Flaig TW. Geriatric considerations in the treatment of advanced prostate cancer. F1000Prime Rep. 2014;6:33. PubMed PMID: 24860655
Kessler ER, Moss A, Eckhardt SG, Laudenslager ML, Kilbourn K, Mauss IB, Bowles DW, Hecker S, Fairclough DL, Kutner JS. Distress among caregivers of phase I trial participants: a cross-sectional study. Support Care Cancer. 2014 Dec;22(12):3331-40. PubMed PMID: 25120010
Lam ET, Kessler ER, Flaig TW, La Rosa FG. Collision renal cell papillary and medullary carcinoma in a 66-year-old man. Oncology (Williston Park). 2013 Sep;27(9):893, 896, 898. PubMed PMID: 24282987
Verdoorn BP, Kessler ER, Flaig TW. Targeted therapy in advanced urothelial carcinoma. Oncology (Williston Park). 2013 Mar;27(3):219-26. PubMed PMID: 23687793
Yang X, La Rosa FG, Genova EE, Huber K, Schaack J, Degregori J, Serkova NJ, Li Y, Su LJ, Kessler E, Flaig TW. Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia. PLoS One. 2013;8(9):e74809. PubMed PMID: 24058630
Yang X, Kessler E, Su LJ, Thorburn A, Frankel AE, Li Y, La Rosa FG, Shen J, Li CY, Varella-Garcia M, Glodé LM, Flaig TW. Diphtheria toxin-epidermal growth factor fusion protein DAB389EGF for the treatment of bladder cancer. Clin Cancer Res. 2013 Jan 1;19(1):148-57. PubMed PMID: 23172881
Care Philosophy
I am interested in Genitourinary Cancers (Prostate, Bladder, Testicular and Kidney Cancers). We strive to provide patient-focused, personalized, multi-disciplinary care for genitourinary (GU) cancers. Our specialized providers in Medical Oncology (chemotherapy and targeted therapies), Urologic Oncology, Radiation Oncology, Pathology, Molecular Pathology, Radiology, Interventional Radiology, Nuclear Medicine, Nutrition, and Integrative Medicine work together to achieve the best outcomes for our patients. We have weekly GU cancer tumor boards, where our specialists come together to discuss patients and patient care.
General Information
Medical Schools:
MD, New York Medical College
(2006)
Undergraduate Schools:
BS, University of Colorado - Boulder (CO)
(2000)
Residency Programs:
University of Colorado (University Hospital) Program, Internal Medicine (2010)
Fellowships:
University of Colorado, Hematology and Oncology
(2013)