Tina Roark, PhD
Assistant Professor, Medicine-Allergy/Clinical Immunology

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Graduate School :
  • PhD, University of Colorado Health Sciences Center (1995)
Undergraduate School:
  • BA, Colorado College (CO) (1990)
Languages: English
Department: Medicine-Allergy/Clinical Immunology

Professional Titles

  • Assistant Professor

Recognition & Awards

  • Summit Award, University of Colorado Department of Pathology (2022)
    Excellence in teaching and the education of pathologists

Publications

  • Roark CL, Ho BE, Aubrey MT, Anobile C, Israeli S, Phang TL, Braxton D, Ho AP, Freed BM. HLA homozygosity is associated with Non-Hodgkin lymphoma. Hum Immunol. 2022 Oct;83(10):730-735. PubMed PMID: 35953408
  • Solomon SR, Aubrey MT, Zhang X, Jackson KC, Roark CL, Freed BM, Morris LE, Holland HK, Solh MM, Bashey A. Lineage-Specific Relapse Prediction After Haploidentical Transplantation With Post-Transplant Cyclophosphamide Based on Recipient HLA-B-Leader Genotype and HLA-C-Group KIR Ligand. Transplant Cell Ther. 2022 Sep;28(9):601.e1-601.e8. PubMed PMID: 35788088
  • Scott R. Solomon, Michael T Aubrey, Xu Zhang, Katelin C Jackson, Christina L Roark, Brian M Freed, Lawrence E Morris, H. Kent Holland, Asad Bashey, Melhem Solh; Recipient HLA-B Leader Genotype, and Its Relationship to Total KIR Missing Ligand, Informs Relapse and Survival Following Haploidentical Transplantation Using Post-Transplant Cyclophosphamide. Blood 2021; 138 (Supplement 1): 418. doi: https://doi.org/10.1182/blood-2021-151496
  • Scott R. Solomon, Michael T Aubrey, Xu Zhang, Melhem Solh, Lawrence E Morris, H. Kent Holland, Katelin C Jackson, Brian M Freed, Christina L Roark, Asad Bashey; Optimizing Donor Selection for Haploidentical Transplantation Utilizing the Four-Group T Cell Epitope (TCE-4) Algorithm for Prediction of HLA-DPB1 Non-Permissive Mismatches. Blood 2021; 138 (Supplement 1): 420. doi: https://doi.org/10.1182/blood-2021-149289
  • C.L. Roark, E.R. Sunderhaus, V. Jha, M. Aubrey, J. Matsuda, B.M. Freed. Editing of the HLA Gene: A Novel Therapy for Autoimmunity. Human Immunology 2021. 82 (Supplement): 44-45. doi: https://doi.org/10.1016/j.humimm.2021.08.002
  • V. Jha, M. Coulombe, E.F. Rosloniec, J. Matsuda, B.M. Freed, C.L. Roark. Gene Editing of DRB1*04:01 at Position 71 Blocks Collagen Sensitization and Avoids Allorecognition. Human Immunology 2021. 82 (Supplement): 39-40. doi: https://doi.org/10.1016/j.humimm.2021.08.002
  • M. Nevski, M. McAuliffe, G. Wedermyer, C.L. Roark, B.M. Freed. De Novo HLA Antibody Production Following Clinical Trial CMV Vaccine. Human Immunology 2021. 82 (Supplement): 66. doi: https://doi.org/10.1016/j.humimm.2021.08.003
  • M. McAuliffe, M. Nevski, G. Wedermyer, C.L. Roark, B.M. Freed. Analysis of HLA Antibodies After COVID-19 mRNA Vaccination in Post-Transplant Kidney Recipients and Healthy Volunteers. Human Immunology 2021. 82 (Supplement): 128. https://doi.org/10.1016/j.humimm.2021.08.003
  • L. Helander, C.L. Roark, B.M. Freed, M.D. Everitt. Donor Specific Antibody After Heart Transplant: Is C1Q Antibody Generated From Memory B-Cells? Human Immunology 2021. 82 (Supplement): 68. https://doi.org/10.1016/j.humimm.2021.08.003
  • Elizabeth Sunderhaus, Anita C. Hohenstein, Rocky L. Baker, Christina L. Roark, Brian M. Freed. Dissecting the Restriction of a Diabetogenic T Cell Clone from an Entire Genotype Using Cloned HLA Molecules. Human Immunology 2021. 82 (Supplement): 135-136. https://doi.org/10.1016/j.humimm.2021.08.003
  • Anderson K, Carey B, Martin A, Roark C, Chalk C, Nowell-Bostic M, Freed B, Aubrey M, Trapnell B, Fontenot A. Pulmonary alveolar proteinosis: An autoimmune disease lacking an HLA association. PLoS One. 2019;14(3):e0213179. PubMed PMID: 30845238
  • Roark CL, Anderson KM, Aubrey MT, Rosloniec EF, Freed BM. Arthritogenic peptide binding to DRB1*01 alleles correlates with susceptibility to rheumatoid arthritis. J Autoimmun. 2016 Aug;72:25-32. PubMed PMID: 27143337
  • Anderson KM, Roark CL, Portas M, Aubrey MT, Rosloniec EF, Freed BM. A Molecular Analysis of the Shared Epitope Hypothesis: Binding of Arthritogenic Peptides to DRB1*04 Alleles. Arthritis Rheumatol. 2016 Jul;68(7):1627-36. PubMed PMID: 26866513
  • Roark CL, Anderson KM, Simon LJ, Schuyler RP, Aubrey MT, Freed BM. Multiple HLA epitopes contribute to type 1 diabetes susceptibility. Diabetes. 2014 Jan;63(1):323-31. PubMed PMID: 24357703
  • Roark CL, Anderson KM, Simon LJ, Schuyler RP, Aubrey MT, and Freed BM. Identification of class I and class II HLA epitopes in type 1 diabetes. Oral presentation at: ASHI 39th Annual Meeting; 2013 Nov 17-21; Chicago, IL.
View All (15 Total) View Less

Professional Memberships

  • American Society for Histocompatibility and Immunogenetics, member

Specialty Information

Specialties
  • Allergy and Immunology
  • Fellow of American College of Histocompatibility and Immunogenetics, Specialized Training (2021)
  • American College of Histocompatibility and Immunogenetics, Board Certification (2017)

General Information

Graduate Schools:
  • PhD, University of Colorado Health Sciences Center (1995)
Undergraduate Schools:
  • BA, Colorado College (CO) (1990)
Languages: English
Department: Medicine-Allergy/Clinical Immunology
SOM Resources
CU Resources
Contact Us
CU Anschutz
Fitzsimons Building
13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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