Jacinda Nicklas, MD, MPH/MSPH

Research Interests

My research is focused on obesity and weight loss. Specifically, I conduct research to decrease weight retention after pregnancy, and to decrease the risk of diabetes and cardiovascular disease in women who are at increased risk.

Publications

• Nicklas JM, Miller LJ, Zera CA, Davis RB, Levkoff SE, Seely EW. Factors associated with depressive symptoms in the early postpartum period among women with recent gestational diabetes mellitus. Maternal Child Health. 2012 Nov 3. [Epub ahead of print] PMID: 23124798
• Zera CA, Nicklas JM, Levkoff SE, England LB, Seely EW. Diabetes risk perception in women with a history of gestational diabetes: Delivery to the postpartum visit. Journal of Maternal Fetal Neonatal Medicine. 2012 Nov 6. [Epub ahead of print]
• Nicklas JM, Sacks FM, Smith SR, LeBoff MS, Bray GA, Ridker PM. Effect of dietary composition, weight loss, and changes in body fat on high sensitivity C-reactive protein: The randomized POUNDS LOST Trial. Obesity (In press).
• Nicklas JM, Miller LJ, Zera CA, Levkoff SE, Seely EW. Factors associated with depressive symptoms at 6 weeks postpartum among women with recent gestational diabetes mellitus. J Gen Intern Med. 2012 Jul;27 Suppl 2:S99-574.
• Seely EW, Rich-Edwards J, Lui J, Nicklas JM, Saxena A, Tsigas E, Levkoff SE. Risk of future cardiovascular disease in women with prior preeclampsia: a focus group study. BMC Pregnancy Childbirth. 2013 Dec 21;13:240. PubMed PMID: 24359495
• Nicklas JM, Sacks FM, Smith SR, LeBoff MS, Rood JC, Bray GA, Ridker PM. Effect of dietary composition of weight loss diets on high-sensitivity c-reactive protein: the Randomized POUNDS LOST trial. Obesity (Silver Spring). 2013 Apr;21(4):681-9. PubMed PMID: 23712970
• Zera CA, Nicklas JM, Levkoff SE, Seely EW. Diabetes risk perception in women with recent gestational diabetes: delivery to the postpartum visit. J Matern Fetal Neonatal Med. 2013 May;26(7):691-6. PubMed PMID: 23131116
• Nicklas JM, Miller LJ, Zera CA, Davis RB, Levkoff SE, Seely EW. Factors associated with depressive symptoms in the early postpartum period among women with recent gestational diabetes mellitus. Matern Child Health J. 2013 Nov;17(9):1665-72. PubMed PMID: 23124798
• Nicklas JM, Zera CA, Rosner BA, Levkoff SE, Seely EW. A web-based lifestyle intervention to decrease postpartum weight retention in women with recent gestational diabetes mellitus: The Balance after Baby pilot RCT. J Gen Intern Med. 2013; 28(1) S14. (abstract)
• Nicklas JM, Zera CA, Seely EW. Patterns of clinician diagnosis leading to the assignment of ICD-9 discharge codes for gestational diabetes. (abstract to be published in Endocrine Reviews)
• Nicklas JM, Zera CA, Levkoff SE, Seely EW. Factors associated with early postpartum weight loss in women with recent gestational diabetes. (abstract to be published in Obesity).
• Nicklas JM, Zera CA, England LJ, Rosner BA, Horton E, Levkoff SE, Seely EW. A web-based lifestyle intervention for women with recent gestational diabetes mellitus: a randomized controlled trial. Obstet Gynecol. 2014 Sep;124(3):563-70. PubMed PMID: 25162257
• Nicklas JM and Barbour LA. Optimizing Weight for Maternal and Infant Health – Tenable, or Too Late? Expert Review of Endocrinology & Metabolism. Early online, 1–16, 2014.
• Nicklas JM, Skurnik G, Zera CA, Reforma LG, Levkoff SE, Seely EW. Employing a Multi-level Approach to Recruit a Representative Sample of Women with Recent Gestational Diabetes Mellitus into a Randomized Lifestyle Intervention Trial. Matern Child Health J. 2015 Oct 31. [Epub ahead of print] PubMed PMID: 26520160
• Jones EJ, Peercy M, Woods JC, Parker SP, Jackson T, Mata SA, McCage S, Levkoff SE, Nicklas JM, Seely EW. Identifying postpartum intervention approaches to reduce cardiometabolic risk among American Indian women with prior gestational diabetes, Oklahoma, 2012-2013. Prev Chronic Dis. 2015 Apr 2;12:E45. PubMed PMID: 25837258
• Nicklas JM, Skurnik G, Zera CA, Reforma LG, Levkoff SE, Seely EW. Employing a Multi-level Approach to Recruit a Representative Sample of Women with Recent Gestational Diabetes Mellitus into a Randomized Lifestyle Intervention Trial. Matern Child Health J. 2016 Feb;20(2):261-9. PubMed PMID: 26520160
• Leiferman J, Gutilla MJ, Nicklas JM, Paulson J. Effect of online education on antenatal physical activity counseling. American Journal of Lifestyle Medicine 3/21/2016.
• Nicklas JM, Zera CA, Lui J, Seely EW. Patterns of gestational diabetes diagnosis inside and outside of clinical guidelines. BMC Pregnancy Childbirth. 2017 Jan 6;17(1):11. PubMed PMID: 28061829
• Leiferman J, Gutilla MJ, Nicklas JM, Paulson J. Effect of Online Training on Antenatal Physical Activity Counseling. Am J Lifestyle Med. 2018 Mar-Apr;12(2):166-174. PubMed PMID: 30202389
• Nicklas JM, Zera CA, Levkoff SE, Seely EW. Change in cardiometabolic risk factors with postpartum changes in weight and waist circumference in women with recent gestational diabetes. Prevention of Chronic Disease.
• Nicklas JM, Zera CA, Seely EW. Predictors of very early postpartum weight loss in women with recent gestational diabetes mellitus. J Matern Fetal Neonatal Med. 2018 Jul 22;:1-7. [Epub ahead of print] PubMed PMID: 30032681
• Nicklas JM, Rosner BA, Zera CA, Seely EW. Association Between Changes in Postpartum Weight and Waist Circumference and Changes in Cardiometabolic Risk Factors Among Women With Recent Gestational Diabetes. Prev Chronic Dis. 2019 Apr 18;16:E47. PubMed PMID: 31002638
• Nicklas JM, Leiferman JA, Lockhart S, Daly KJ, Bull SS, Barbour LA. Development and modification of a mobile health program to promote postpartum weight loss in women at elevated risk for cardiometabolic disease: A single arm pilot study. JMIR Formative Research (In Press)
• Seely EW, Celi AC, Chausmer J, Graves C, Kilpatrick S, Nicklas JM, Rosser ML, Rexrode KM, Stuart JJ, Tsigas E, Voelker J, Zelop C, Rich-Edwards JW. Cardiovascular Health After Preeclampsia: Patient and Provider Perspective. J Womens Health (Larchmt). 2020 Sep 28. [Epub ahead of print] PubMed PMID: 32986503
• Nicklas JM, Leiferman JA, Lockhart S, Daly KM, Bull SS, Barbour LA. Development and Modification of a Mobile Health Program to Promote Postpartum Weight Loss in Women at Elevated Risk for Cardiometabolic Disease: Single-Arm Pilot Study. JMIR Form Res. 2020 Apr 9;4(4):e16151. PubMed PMID: 32271149
• Nicklas JM, Zera CA, Seely EW. Predictors of very early postpartum weight loss in women with recent gestational diabetes mellitus. J Matern Fetal Neonatal Med. 2020 Jan;33(1):120-126. PubMed PMID: 30032681
• Farewell CV, Donohoe R, Thayer Z, Paulson J, Nicklas J, Walker C, Waldie K, Leiferman JA. Maternal depression trajectories and child BMI in a multi-ethnic sample: a latent growth modeling analysis. BMC Pregnancy Childbirth. 2021 Dec 13;21(1):827. PubMed PMID: 34903186
• Blair RA, Neves JS, Nicklas JM, Horn CE, Skurnik G, Seely EW. Breastfeeding Associated with Lower Prevalence of Metabolic Syndrome in Women with Gestational Diabetes in the Very Early Postpartum Period. Am J Perinatol. 2021 Oct 20. [Epub ahead of print] PubMed PMID: 34670318
• Seely EW, Celi AC, Chausmer J, Graves C, Kilpatrick S, Nicklas JM, Rosser ML, Rexrode KM, Stuart JJ, Tsigas E, Voelker J, Zelop C, Rich-Edwards JW. Cardiovascular Health After Preeclampsia: Patient and Provider Perspective. J Womens Health (Larchmt). 2021 Mar;30(3):305-313. PubMed PMID: 32986503
• Bramante CT, Buse J, Tamaritz L, Palacio A, Cohen K, Vojta D, Liebovitz D, Mitchell N, Nicklas J, Lingvay I, Clark JM, Aronne LJ, Anderson E, Usher M, Demmer R, Melton GB, Ingraham N, Tignanelli CJ. Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity. J Med Virol. 2021 Jul;93(7):4273-4279. PubMed PMID: 33580540
• McCloskey L, Bernstein J, The Bridging The Chasm Collaborative, Amutah-Onukagha N, Anthony J, Barger M, Belanoff C, Bennett T, Bird CE, Bolds D, Brenna BW, Carter R, Celi A, Chachere B, Crear-Perry J, Crossno C, Cruz-Davis A, Damus K, Dangel A, Depina Z, Deroze P, Dieujuste C, Dude A, Edmonds J, Enquobahrie D, Eromosele E, Ferranti E, Fitzmaurice M, Gebel C, Blount LG, Greiner A, Gullo S, Haddad A, Hall N, Handler A, Headen I, Heelan-Fancher L, Hernandez T, Johnson K, Jones E, Jones N, Klaman S, Lund B, Mallampalli M, Marcelin L, Marshall C, Maynard B, McCage S, Mitchell S, Molina R, Montasir S, Nicklas J, Northrup A, Norton A, Oparaeke E, Ramos A, Rericha S, Rios E, Bloch JR, Ryan C, Sarfaty S, Seely E, Souter V, Spain M, Spires R, Theberge S, Thompson T, Wachman M, Yarrington T, Yee LM, Zera C, Clayton J, Lachance C. Bridging the Chasm between Pregnancy and Health over the Life Course: A National Agenda for Research and Action. Womens Health Issues. 2021 May-Jun;31(3):204-218. PubMed PMID: 33707142
• Bramante CT, Buse JB, Liebovitz D, Nicklas J, Puskarich MA, Cohen K, Belani H, Anderson B, Huling JD, Tignanelli C, Thompson J, Pullen M, Siegel L, Proper J, Odde DJ, Klatt N, Sherwood N, Lindberg S, Wirtz EL, Karger A, Beckman K, Erickson S, Fenno S, Hartman K, Rose M, Patel B, Griffiths G, Bhat N, Murray TA, Boulware DR. Outpatient treatment of Covid-19 with metformin, ivermectin, and fluvoxamine and the development of Long Covid over 10-month follow-up. medRxiv. 2022 Dec 23. PubMed PMID: 36597543
• Seely EW, Ritchie ND, Nicklas JM, Levkoff SE. Diabetes in Women After Gestational Diabetes: A Missed Opportunity for Prevention. Am J Prev Med. 2023 Jan;64(1):137-141. PubMed PMID: 36180315
• Boulware DR, Murray TA, Proper JL, Tignanelli CJ, Buse JB, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Siegel LK, Klatt NR, Odde DJ, Karger AB, Ingraham NE, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Lindberg S, Fricton R, Lee S, Zaman A, Saveraid HG, Tordsen WJ, Pullen MF, Sherwood NE, Huling JD, Bramante CT. Impact of SARS-CoV-2 vaccination and booster on COVID-19 symptom severity over time in the COVID-OUT trial. Clin Infect Dis. 2022 Sep 17. [Epub ahead of print] PubMed PMID: 36124697
• Bramante CT, Huling JD, Tignanelli CJ, Buse JB, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Proper JL, Siegel LK, Klatt NR, Odde DJ, Luke DG, Anderson B, Karger AB, Ingraham NE, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Lindberg S, Fricton R, Lee S, Zaman A, Saveraid HG, Tordsen WJ, Pullen MF, Biros M, Sherwood NE, Thompson JL, Boulware DR, Murray TA. Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19. N Engl J Med. 2022 Aug 18;387(7):599-610. PubMed PMID: 36070710
• Avula N, Kakach D, Tignanelli CJ, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Buse JB, Klatt NR, Anderson B, Karger AB, Hartman KM, Patel B, Fenno SL, Reddy NV, Erickson SM, Boulware DR, Murray TA, Bramante CT. Strategies used for the COVID-OUT decentralized trial of outpatient treatment of SARS-CoV-2. J Clin Transl Sci. 2023;7(1):e242. PubMed PMID: 38033705
• Elmaleh-Sachs A, Schwartz JL, Bramante CT, Nicklas JM, Gudzune KA, Jay M. Obesity Management in Adults: A Review. JAMA. 2023 Nov 28;330(20):2000-2015. PubMed PMID: 38015216
• Bramante CT, Proper JL, Boulware DR, Karger AB, Murray T, Rao V, Hagen A, Tignanelli CJ, Puskarich M, Cohen K, Liebovitz DM, Klatt NR, Broedlow C, Hartman KM, Nicklas J, Ibrahim S, Zaman A, Saveraid H, Belani H, Ingraham N, Christensen G, Siegel L, Sherwood NE, Fricton R, Lee S, Odde DJ, Buse JB, Huling JD. Vaccination Against SARS-CoV-2 Is Associated With a Lower Viral Load and Likelihood of Systemic Symptoms. Open Forum Infect Dis. 2022 May;9(5):ofac066. PubMed PMID: 35392460
• Bramante CT, Beckman KB, Mehta T, Karger AB, Odde DJ, Tignanelli CJ, Buse JB, Johnson DM, Watson RHB, Daniel JJ, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Siegel LK, Klatt NR, Anderson B, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Fricton RD, Lee S, Griffiths G, Pullen MF, Thompson JL, Sherwood N, Murray TA, Rose MR, Boulware DR, Huling JD. Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial. medRxiv. 2023 Jun 7. PubMed PMID: 37333243
• Bramante CT, Buse JB, Liebovitz DM, Nicklas JM, Puskarich MA, Cohen K, Belani HK, Anderson BJ, Huling JD, Tignanelli CJ, Thompson JL, Pullen M, Wirtz EL, Siegel LK, Proper JL, Odde DJ, Klatt NR, Sherwood NE, Lindberg SM, Karger AB, Beckman KB, Erickson SM, Fenno SL, Hartman KM, Rose MR, Mehta T, Patel B, Griffiths G, Bhat NS, Murray TA, Boulware DR. Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial. Lancet Infect Dis. 2023 Oct;23(10):1119-1129. PubMed PMID: 37302406
• Thompson DA, Haemer MA, Krebs NF, Pereira RI, Moss A, Furniss AL, Bonczynski J, Nicklas JM. A WIC-Based Behavior Change Intervention for Postpartum Women With Overweight and Obesity: A Pilot Feasibility Randomized Trial. Health Promot Pract. 2023 May 25;:15248399231173704. [Epub ahead of print] PubMed PMID: 37226873
• Farewell CV, Thayer Z, Paulson J, Nicklas J, Walker C, Waldie K, Morton S, Leiferman JA. Fostering Resilience Among Mothers Early (FRAME): using growth mixture modeling to identify resources that mitigate perinatal depression. Arch Womens Ment Health. 2022 Apr;25(2):451-461. PubMed PMID: 35137331
• Rosenberg EA, Seely EW, James K, Soffer MD, Nelson S, Nicklas JM, Powe CE. Carbohydrate Intake and Oral Glucose Tolerance Test Results in the Postpartum Period. J Clin Endocrinol Metab. 2023 Sep 18;108(10):e1007-e1012. PubMed PMID: 37097924
• Dusek JA, Gao Q, Kim RS, Abrams DI, Kligler B, Dyer NL, Hansen K, McKee MD. Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER) of the BraveNet practice-based research network: Outcomes of the PRIMIER cohort. Complement Ther Med. 2022 Dec;71:102904. PubMed PMID: 36435299
• Horn CE, Seely EW, Levkoff SE, Isley BC, Nicklas JM. Postpartum women's experiences in a randomized controlled trial of a web-based lifestyle intervention following Gestational Diabetes: a qualitative study. J Matern Fetal Neonatal Med. 2023 Dec;36(1):2194012. PubMed PMID: 36977603
• Ritchie ND, Seely EW, Nicklas JM, Levkoff SE. Effectiveness of the National Diabetes Prevention Program After Gestational Diabetes. Am J Prev Med. 2023 Aug;65(2):317-321. PubMed PMID: 36918133
• Seely EW, Ritchie ND, Nicklas JM, Levkoff SE. Diabetes in Women After Gestational Diabetes: A Missed Opportunity for Prevention. Am J Prev Med. 2023 Jan;64(1):137-141. PubMed PMID: 36180315
• Boulware DR, Murray TA, Proper JL, Tignanelli CJ, Buse JB, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Siegel LK, Klatt NR, Odde DJ, Karger AB, Ingraham NE, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Lindberg S, Fricton R, Lee S, Zaman A, Saveraid HG, Tordsen WJ, Pullen MF, Sherwood NE, Huling JD, Bramante CT. Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Booster on Coronavirus Disease 2019 (COVID-19) Symptom Severity Over Time in the COVID-OUT Trial. Clin Infect Dis. 2023 Feb 8;76(3):e1-e9. PubMed PMID: 36124697
• Saxon CE, Seely EW, Bertin KB, et al. Self-Efficacy and Readiness to Change Among Women with Recent Gestational Diabetes Engaging in a Web-Based Lifestyle Intervention: The Balance After Baby Intervention Trial. American Journal of Lifestyle Medicine. 2023;0(0). doi:10.1177/15598276231155147

Professional Memberships

• Society for General Internal Medicine (SGIM), Member
• Association for Patient Oriented Research (APOR), Member

Practice Locations

UCHealth Internal Medicine - Anschutz Medical Campus
1635 Aurora Ct
5th Floor
Aurora, CO 80045
720-848-2300

CU Medicine Weight Management and Wellness - CU Anschutz Health and Wellness Center
12348 E Montview Boulevard
Aurora, CO 80045
303-724-9030

Hospital Affiliation

• University of Colorado Hospital

Specialty Information

Specialties

• Internal Medicine, Board Certification (2008)
• Obesity Medicine

Conditions & Treatments

• Food, Nutrition and Metabolism - Nutrition
• Food, Nutrition and Metabolism - Obesity
• Food, Nutrition and Metabolism - Weight Loss and Dieting
• Complementary and Alternative Therapies
• Wellness and Prevention - Exercise and Physical Fitness
• Food, Nutrition and Metabolism
• Wellness and Prevention