Beth Tamburini, PhD

Publications

• T cell vaccinology: exploring the known unknowns. Burchill MA, Tamburini BA, Pennock ND, White JT, Kurche JS, Kedl RM. Vaccine. 2013 Jan 2;31(2):297-305. doi: 10.1016/j.vaccine.2012.10.096. Epub 2012 Nov 6. PMID: 23137843 [PubMed - in process]
• Pennock ND, White JT, Cross EW, Cheney EE, Tamburini BA, Kedl RM. T cell responses: naive to memory and everything in between. Adv Physiol Educ. 2013 Dec;37(4):273-83. PubMed PMID: 24292902
• Burchill MA, Tamburini BA, Pennock ND, White JT, Kurche JS, Kedl RM. T cell vaccinology: exploring the known unknowns. Vaccine. 2013 Jan 2;31(2):297-305. PubMed PMID: 23137843
• Tamburini BA, Burchill MA, Kedl RM. Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection. Nat Commun. 2014 Jun 6;5:3989. PubMed PMID: 24905362
• T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs. Burchill MA, Tamburini BA, Kedl RM. Eur J Immunol. 2015 Nov;45(11):3140-9. doi: 10.1002/eji.201545749. Epub 2015 Aug 3. PMID: 26179759
• Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium. Kedl RM, Tamburini BA. Eur J Immunol. 2015 Oct;45(10):2721-9. doi: 10.1002/eji.201545739. Epub 2015 Sep 10. Review. PMID: 26278423
• Kedl RM, Lindsay RS, Finlon JM, Lucas ED, Friedman RS, Tamburini BAJ. Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction. Nat Commun. 2017 Dec 11;8(1):2034. PubMed PMID: 29229919
• Elder AM, Tamburini BAJ, Crump LS, Black SA, Wessells VM, Schedin PJ, Borges VF, Lyons TR. Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer. Cancer Res. 2018 Nov 15;78(22):6473-6485. PubMed PMID: 30254150
• Lucas ED, Finlon JM, Burchill MA, McCarthy MK, Morrison TE, Colpitts TM, Tamburini BAJ. Type 1 IFN and PD-L1 Coordinate Lymphatic Endothelial Cell Expansion and Contraction during an Inflammatory Immune Response. J Immunol. 2018 Sep 15;201(6):1735-1747. PubMed PMID: 30045970
• McCarthy MK, Davenport BJ, Reynoso GV, Lucas ED, May NA, Elmore SA, Tamburini BA, Hickman HD, Morrison TE. Chikungunya virus impairs draining lymph node function by inhibiting HEV-mediated lymphocyte recruitment. JCI Insight. 2018 Jul 12;3(13). [Epub ahead of print] PubMed PMID: 29997290
• Kedl RM, Lindsay RS, Finlon JM, Lucas ED, Friedman RS, Tamburini BAJ. Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction. Nat Commun. 2017 Dec 11;8(1):2034. PubMed PMID: 29229919
• Finlon JM, Burchill MA, Tamburini BAJ. Digestion of the Murine Liver for a Flow Cytometric Analysis of Lymphatic Endothelial Cells. JoVE. In Press.
• Tamburini BAJ, Padera TP, Lund AW. Editorial: Regulation of Immune Function by the Lymphatic Vasculature. Front Immunol. 2019;10:2597. PubMed PMID: 31781105
• Tamburini BAJ, Elder AM, Finlon JM, Winter AB, Wessells VM, Borges VF, Lyons TR. PD-1 Blockade During Post-partum Involution Reactivates the Anti-tumor Response and Reduces Lymphatic Vessel Density. Front Immunol. 2019;10:1313. PubMed PMID: 31244852
• Tamburini BAJ, Finlon JM, Gillen AE, Kriss MS, Riemondy KA, Fu R, Schuyler RP, Hesselberth JR, Rosen HR, Burchill MA. Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells. Front Immunol. 2019;10:1036. PubMed PMID: 31156626
• Lucas ED, Tamburini BAJ. Lymph Node Lymphatic Endothelial Cell Expansion and Contraction and the Programming of the Immune Response. Front Immunol. 2019;10:36. PubMed PMID: 30740101
• Finlon JM, Burchill MA, Tamburini BAJ. Digestion of the Murine Liver for a Flow Cytometric Analysis of Lymphatic Endothelial Cells. J Vis Exp. 2019 Jan 7;(143). PubMed PMID: 30663671
• Tu MM, Abdel-Hafiz HA, Jones RT, Jean A, Hoff KJ, Duex JE, Chauca-Diaz A, Costello JC, Dancik GM, Tamburini BAJ, Czerniak B, Kaye J, Theodorescu D. Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy. Commun Biol. 2020 Nov 27;3(1):720. PubMed PMID: 33247183
• Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020 Nov 17;33(7):108407. PubMed PMID: 33207208
• Lucas ED, Schafer JB, Matsuda J, Kraus M, Burchill MA, Tamburini BAJ. PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity. Cell Rep. 2020 Oct 13;33(2):108258. PubMed PMID: 33053342
• Burchill MA, Goldberg AR, Tamburini BAJ. Emerging Roles for Lymphatics in Chronic Liver Disease. Front Physiol. 2020;10:1579. PubMed PMID: 31992991
• Burchill, MA, Finlon, JM, Goldberg, A, Gillen, AE, Dahms, P, McMahan, RH, Winter, A, Bohrnsen, E, Reisz, JA, Orlicky, DJ, Kriss, MS, Rosen, H, McCullough, R and Tamburini, BAJ. Oxidized Low-Density Lipoprotein drives dysfunction of the liver lymphatic system. Cellular and Molecular Gastroenterology and Hepatology. 2020; in press. DOI:https://doi.org/10.1016/j.jcmgh.2020.09.007
• Carpentier KS, Sheridan RM, Lucas CJ, Davenport BJ, Li FS, Lucas ED, McCarthy MK, Reynoso GV, May NA, Tamburini BAJ, Hesselberth JR, Hickman HD, Morrison TE. MARCO( ) lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination. EMBO J. 2021 Nov 15;40(22):e108966. PubMed PMID: 34618370
• Tamburini BAJ. Contributions of PD-L1 reverse signaling to dendritic cell trafficking. FEBS J. 2021 Jun 19. [Epub ahead of print] PubMed PMID: 34146376
• Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis. J Immunother Cancer. 2021 Apr;9(4). PubMed PMID: 33883256
• Walsh SM, Sheridan RM, Lucas ED, Doan TA, Ware BC, Schafer J, Fu R, Burchill MA, Hesselberth JR, Tamburini BAJ. Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node. Elife. 2021 Apr 12;10. PubMed PMID: 33843587
• Schafer JB, Lucas ED, Dzieciettkowska M, Forward T, Tamburini BAJ. Programmed death ligand 1 intracellular interactions with STAT3 and focal adhesion protein Paxillin facilitate lymphatic endothelial cell remodeling. J Biol Chem. 2022 Nov 11;:102694. [Epub ahead of print] PubMed PMID: 36375639
• Burchill MA, Finlon JM, Goldberg AR, Gillen AE, Dahms PA, McMahan RH, Tye A, Winter AB, Reisz JA, Bohrnsen E, Schafer JB, D'Alessandro A, Orlicky DJ, Kriss MS, Rosen HR, McCullough RL, Jirón Tamburini BA. Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System. Cell Mol Gastroenterol Hepatol. 2021;11(2):573-595. PubMed PMID: 32961356
• Goldberg AR, Ferguson M, Pal S, Cohen R, Orlicky DJ, McCullough RL, Rutkowski JM, Burchill MA, Tamburini BAJ. Oxidized low density lipoprotein in the liver causes decreased permeability of liver lymphatic- but not liver sinusoidal-endothelial cells via VEGFR-3 regulation of VE-Cadherin. Front Physiol. 2022;13:1021038. PubMed PMID: 36338478
• Doan TA, Forward T, Tamburini BAJ. Trafficking and retention of protein antigens across systems and immune cell types. Cell Mol Life Sci. 2022 May 3;79(5):275. PubMed PMID: 35505125
• Carpentier KS, Sheridan RM, Lucas CJ, Davenport BJ, Li FS, Lucas ED, McCarthy MK, Reynoso GV, May NA, Tamburini BAJ, Hesselberth JR, Hickman HD, Morrison TE. MARCO( ) lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination. EMBO J. 2021 Nov 15;40(22):e108966. PubMed PMID: 34618370
• Tamburini BAJ. Contributions of PD-L1 reverse signaling to dendritic cell trafficking. FEBS J. 2022 Oct;289(20):6256-6266. PubMed PMID: 34146376
• Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis. J Immunother Cancer. 2021 Apr;9(4). PubMed PMID: 33883256
• Walsh SM, Sheridan RM, Lucas ED, Doan TA, Ware BC, Schafer J, Fu R, Burchill MA, Hesselberth JR, Tamburini BAJ. Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node. Elife. 2021 Apr 12;10. PubMed PMID: 33843587
• Burchill MA, Finlon JM, Goldberg AR, Gillen AE, Dahms PA, McMahan RH, Tye A, Winter AB, Reisz JA, Bohrnsen E, Schafer JB, D'Alessandro A, Orlicky DJ, Kriss MS, Rosen HR, McCullough RL, Jirón Tamburini BA. Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System. Cell Mol Gastroenterol Hepatol. 2021;11(2):573-595. PubMed PMID: 32961356
• Lucas CJ, Sheridan RM, Reynoso GV, Davenport BJ, McCarthy MK, Martin A, Hesselberth JR, Hickman HD, Tamburini BAJ, Morrison TE. Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO. bioRxiv. 2023 Oct 13. PubMed PMID: 37873393
• Tamburini B, Doan T, Forward T, Lucas E, Fleming I, Uecker-Martin A, Hesselberth J, Morrison T. Vaccine-induced antigen archiving enhances local memory CD8 T cell responses following an unrelated viral infection. Res Sq. 2023 Sep 25. PubMed PMID: 37841845
• Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jirón Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 Nov 7;31(11):1630-1649.e8. PubMed PMID: 39413777
• Burtis AEC, DeNicola DMC, Ferguson ME, Santos RG, Pinilla C, Kriss MS, Orlicky DJ, Tamburini BAJ, Gillen AE, Burchill MA. Ag-driven CD8 T cell clonal expansion is a prominent feature of MASH in humans and mice. Hepatology. 2024 Jul 24. [Epub ahead of print] PubMed PMID: 39047085
• Sheridan RM, Doan TA, Lucas C, Forward TS, Uecker-Martin A, Morrison TE, Hesselberth JR, Tamburini BAJ. A specific and portable gene expression program underlies antigen archiving by lymphatic endothelial cells. bioRxiv. 2024 Apr 2. PubMed PMID: 38617225
• Doan TA, Forward TS, Schafer JB, Lucas ED, Fleming I, Uecker-Martin A, Ayala E, Guthmiller JJ, Hesselberth JR, Morrison TE, Tamburini BAJ. Immunization-induced antigen archiving enhances local memory CD8 T cell responses following an unrelated viral infection. NPJ Vaccines. 2024 Mar 21;9(1):66. PubMed PMID: 38514656
• Lucas CJ, Sheridan RM, Reynoso GV, Davenport BJ, McCarthy MK, Martin A, Hesselberth JR, Hickman HD, Tamburini BA, Morrison TE. Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO. JCI Insight. 2024 Jan 9;9(4). PubMed PMID: 38194268

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000