Rachael Rzasa Lynn, MD

Professional Titles

• Associate Professor
• Interventional Pain Physician

Research Interests

Publications

• Loram LC, Taylor FR, Strand KA, Harrison JA, Rzasalynn R, Sholar P, Rieger J, Maier SF, Watkins LR. Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling. Brain Behav Immun. 2013 October; 33:112-22.
• Pian P, Labovitz E, Hoffman K, Clavijo CF, Rzasa Lynn R, Galinkin JL, Vinks AA, Malik P, Christians U. Quantification of the 5-lipoxygenase inhibitor zileuton in human plasma using high performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 October 15; 937:79-83.
• Clavijo CF, Rzasa Lynn R, Christians U, Galinkin JL. Intranasal fentanyl for breakthrough pain control. Clinical Medicine Insights: Therapeutics. 2012; 4:241-250.
• Dalesio NM, McMichael H, Rzasa Lynn R, Pho H, Arias R, Gali JL. Morphine metabolism in diet-induced obese mice compared to leptin-deficient obese mice. Poster session presented at: American Society of Anesthesiology; 2013 October 12-16; San Francisco, CA.
• Dalesio NM, Hendrix CW, McMichael DH, Thompson CB, Lee CK, Pho H, Arias RS, Lynn RR, Galinkin J, Yaster M, Brown RH, Schwartz AR. Effects of Obesity and Leptin Deficiency on Morphine Pharmacokinetics in a Mouse Model. Anesth Analg. 2016 Dec;123(6):1611-1617. PubMed PMID: 27782940
• Lamborn N, Vellore A, Nguyen T, Rzasa Lynn R. Celiac plexus block as a diagnostic and therapeutic treatment option for median arcuate ligament syndrome: a case report. Poster presented at the 15th Annual Pain Medicine Meeting. American Society of Regional Anesthesia and Pain Medicine; 2016 Nov 17-19; San Diego, CA.
• McLaughlin L, McLaughlin K, Vellore A, Rzasa-Lynn R. The Misuse of ‘Stigmatization’ in Chronic Pain Patients. Int J Clin Anesthesiol 2016; 4(2):1058.
• Rzasa Lynn R, Galinkin J. Naloxone dosage for opioid reversal: current evidence and clinical implications. Therapeutic Advances in Drug Safety. (in press)
• Nguyen T, Johnson L, Vellore A, Rzasa Lynn R. Influence of provider and radiology technician radiation safety practice on radiation exposure among interventional pain specialists.  Poster presented at the 16th Annual Pain Medicine Meeting. American Society of Regional Anesthesia and Pain Medicine; 2017 Nov 16-18; Orlando, FL
• McLaughlin L, Rzasa Lynn R.  Use of ultrasound guided radio frequency ablation of the mandibular nerve in the treatment of metastatic cancer pain: a case report. Poster presented at the 16th Annual Pain Medicine Meeting. American Society of Regional Anesthesia and Pain Medicine; 2017 Nov 16-18; Orlando, FL
• McLaughlin L, Wallace A, Rzasa Lynn R. An academic interventional pain clinic's independent review of pharmacological adherence: what do we know?  Poster presented at the 16th Annual Pain Medicine Meeting. American Society of Regional Anesthesia and Pain Medicine; 2017 Nov 16-18; Orlando, FL
• Behm A, Loyd J, Hendrickse A, Nguyen T, Rzasa Lynn R.  Is an Epidural Blood Patch Really Necessary? Post Dural Puncture Headache after Transforaminal Epidural Steroid Injection. Poster presented at the 42nd Annual Regional Anesthesia & Acute Pain Medicine Meeting. American Society of Regional Anesthesia and Pain Medicine; 2017 Apr 6-8; San Francisco, CA.
• Moraska AF, Hickner RC, Rzasa-Lynn R, Shah JP, Hebert JR, Kohrt WM. Increase in Lactate Without Change in Nutritive Blood Flow or Glucose at Active Trigger Points Following Massage: A Randomized Clinical Trial. Arch Phys Med Rehabil. 2018 Nov;99(11):2151-2159. PubMed PMID: 30092205
• Rzasa Lynn R, Galinkin JL. Naloxone dosage for opioid reversal: current evidence and clinical implications. Ther Adv Drug Saf. 2018 Jan;9(1):63-88. PubMed PMID: 29318006
• Davari B, Kotecha N, Clavijo CF, Thomas JJ, Rzasa-Lynn R, Galinkin JL, Christians U, Sempio C. A SENSITIVE LC-MS/MS ASSAY FOR THE QUANTIFICATION OF METHADONE AND ITS METABOLITES IN DRIED BLOOD SPOTS: COMPARISON WITH PLASMA. Ther Drug Monit. 2019 Jul 15. [Epub ahead of print] PubMed PMID: 31318842
• Davari B, Kotecha N, Clavijo CF, Thomas JJ, Rzasa-Lynn R, Galinkin JL, Christians U, Sempio C. A Sensitive LC-MS/MS Assay for the Quantification of Methadone and its Metabolites in Dried Blood Spots: Comparison With Plasma. Ther Drug Monit. 2020 Feb;42(1):118-128. PubMed PMID: 31318842
• Friedrich J, Itano EM, Lynn RR. Management of Cardiac Implantable Electrical Devices in Patients Undergoing Radiofrequency Ablation for Spine Pain: Physician Survey and Review of Guidelines. Pain Physician. 2020 Jul;23(4):E335-E342. PubMed PMID: 32709179
• Lynn RSR, Galinkin JL. Cannabis, e-cigarettes and anesthesia. Curr Opin Anaesthesiol. 2020 Jun;33(3):318-326. PubMed PMID: 32371642
• Leroux A, Rzasa-Lynn R, Crainiceanu C, Sharma T. Wearable Devices: Current Status and Opportunities in Pain Assessment and Management. Digit Biomark. 2021 Jan-Apr;5(1):89-102. PubMed PMID: 34056519
• Davari B, Kotecha N, Clavijo CF, Thomas JJ, Rzasa-Lynn R, Galinkin JL, Christians U, Sempio C. A Sensitive LC-MS/MS Assay for the Quantification of Methadone and its Metabolites in Dried Blood Spots: Comparison With Plasma. Ther Drug Monit. 2020 Feb;42(1):118-128. PubMed PMID: 31318842
• Leroux A, Rzasa-Lynn R, Crainiceanu C, Sharma T. Wearable Devices: Current Status and Opportunities in Pain Assessment and Management. Digit Biomark. 2021 Jan-Apr;5(1):89-102. PubMed PMID: 34056519
• Shah S, Schwenk ES, Sondekoppam RV, Clarke H, Zakowski M, Rzasa-Lynn RS, Yeung B, Nicholson K, Schwartz G, Hooten WM, Wallace M, Viscusi ER, Narouze S. ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids. Reg Anesth Pain Med. 2023 Mar;48(3):97-117. PubMed PMID: 36596580
• Niemeyer CS, Harlander-Locke M, Bubak AN, Rzasa-Lynn R, Birlea M. Trigeminal Postherpetic Neuralgia: From Pathophysiology to Treatment. Curr Pain Headache Rep. 2024 Apr;28(4):295-306. PubMed PMID: 38261232
• Rzasa Lynn RS, Henthorn TK, Zuk J, Hammer GB, Drover DR, Levy RJ, Maxwell LG, Sadhasivam S, Suresh S, Galinkin JL. Multicenter Population Pharmacokinetics of Fentanyl in Neonatal Surgical Patients Using Dried Blood Spot Specimen Collection Demonstrates Maturation of Elimination Clearance. Anesth Analg. 2024 Feb 1;138(2):447-455. PubMed PMID: 38215717
• Shah S, Schwenk ES, Sondekoppam RV, Clarke H, Zakowski M, Rzasa-Lynn RS, Yeung B, Nicholson K, Schwartz G, Hooten WM, Wallace M, Viscusi ER, Narouze S. ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids. Reg Anesth Pain Med. 2023 Mar;48(3):97-117. PubMed PMID: 36596580

Practice Locations

• University of Colorado Hospital

Specialty Information

• Pain Medicine, Board Certification
• Anesthesiology, Board Certification

• Complementary and Alternative Therapies
• Spine - Cervical disc herniation
• Spine
• Spine - Degenerative Disc Disease
• Spine - Lumbar disc herniation
• Spine - Radiculopathy
• Spine - Sacroiliac Joint
• Spine - Sciatica
• Circulatory System and Blood Vessel Health - TOS - Thoracic Outlet Syndrome
• Circulatory System and Blood Vessel Health
• Brain and Nervous System - Migraine
• Brain and Nervous System
• Brain and Nervous System - Trigeminal Neuralgia
• Bones, Joints and Muscles - Arthritis
• Bones, Joints and Muscles
• Bones, Joints and Muscles - Back Pain
• Bones, Joints and Muscles - Fibromyalgia
• Bones, Joints and Muscles - Hip Injuries and Disorders
• Bones, Joints and Muscles - Neck Disorders and Injuries
• Symptoms and Manifestations - Abdominal Pain
• Symptoms and Manifestations
• Symptoms and Manifestations - Headache
• Symptoms and Manifestations - Pain