Saketh Guntupalli, MD

Professional Titles

• Director-Division of Gynecologic Oncology
• Karen M. Jennison Endowed Chair in Gynecologic Oncology

Recognitions

• Resident of the Year- Department of Obstetrics and Gynecology- Chief Year, Baylor College of Medicine (2009)
  

Research Interests

Publications

• Matei DE, Enserro DM, Randall ME, Mutch D, Small W, DiSilvestro PA, Spirtos NM, O'Malley DM, Cantuaria GH, Michelin D, Waggoner S, Shahin M, Guntupalli S, Lara O, Ueland FR, Warshal D, Bonebrake A, Tewari KS, Tan A, Powell MA, Walker JL, Santin AD, Kim JH, Miller DS. Long-Term Follow-Up and Overall Survival in NRG258, a Randomized Phase III Trial of Chemoradiation Versus Chemotherapy for Locally Advanced Endometrial Carcinoma. J Clin Oncol. 2024 Dec 19;:JCO2401121. [Epub ahead of print] PubMed PMID: 39700442
• Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, To F, Lin S, Villagomez FR, Jeong AD, Guntupalli SR, Behbakht K, Gibaja V, Arnoult N, Chuong EB, Bitler BG. EHMT1/2 Inhibition Promotes Regression of Therapy-Resistant Ovarian Cancer Tumors in a CD8 T-cell-Dependent Manner. Mol Cancer Res. 2024 Dec 3;22(12):1117-1127. PubMed PMID: 39136655
• Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, To F, Jeong AD, Guntupalli SR, Behbakht K, Gibaja V, Arnoult N, Cocozaki A, Chuong EB, Bitler BG. Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation. Mol Cancer Ther. 2024 Jun 12;:OF1-OF16. [Epub ahead of print] PubMed PMID: 38863225
• Floyd J, Porragas-Paseiro H, Nguyen C, Moroney MR, Mastroyannis S, Guntupalli SR. Validation of the Safety and Efficacy of Apixaban as Postoperative Thromboembolism Prophylaxis for Patients with Gynecologic Malignancies. Ann Surg Oncol. 2024 Aug;31(8):5102-5110. PubMed PMID: 38780692
• Li Y, Ettah U, Jacques S, Gaikwad H, Monte A, Dylla L, Guntupalli S, Moghimi SM, Simberg D. Optimized Enzyme-Linked Immunosorbent Assay for Anti-PEG Antibody Detection in Healthy Donors and Patients Treated with PEGylated Liposomal Doxorubicin. Mol Pharm. 2024 Jun 3;21(6):3053-3060. PubMed PMID: 38743264
• Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, To F, Jeong AD, Guntupalli SR, Behbakht K, Gibaja V, Arnoult N, Cocozaki A, Chuong EB, Bitler BG. Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation. Mol Cancer Ther. 2024 May 8. [Epub ahead of print] PubMed PMID: 38714351
• Guntupalli S. Practical implications of the ADNEX risk prediction model for diagnosis of ovarian cancer. BMJ Med. 2024;3(1):e000896. PubMed PMID: 38596815
• Helm ED, Guntupalli SR. A rare case of cardiac metastasis of squamous cell carcinoma of the cervix with a review of existing case reports and treatment modalities. Gynecol Oncol Rep. 2024 Apr;52:101352. PubMed PMID: 38495801
• Davies KD, Smith LP, Guimaraes-Young A, Corr BR, Fisher CM, Guntupalli SR, Berning AA, Post MD, Pino D, Aisner DL, Wolsky RJ. Prospective Clinical Prognostication of Endometrial Carcinomas Based on Next-Generation Sequencing and Immunohistochemistry-Real-World Implementation and Results at a Tertiary Care Center. Int J Gynecol Pathol. 2024 Jul 1;43(4):335-348. PubMed PMID: 37922951
• Navi BB, Zhang C, Kaiser JH, Liao V, Cushman M, Kasner SE, Elkind MSV, Tagawa ST, Guntupalli SR, Gaudino MFL, Lee AYY, Khorana AA, Kamel H. Cancer and the risk of perioperative arterial ischaemic events. Eur Heart J Qual Care Clin Outcomes. 2024 Jun 20;10(4):345-356. PubMed PMID: 37757472
• Thomson CA, Crane TE, Miller A, Gold MA, Powell M, Bixel K, Van Le L, DiSilvestro P, Ratner E, Lele S, Guntupalli S, Huh W, Robertson SE, Modesitt S, Casey AC, Basen-Engquist K, Skiba M, Walker J, Kachnic L, Alberts DS. Lifestyle intervention in ovarian cancer enhanced survival (LIVES) study (NRG/GOG0225): Recruitment, retention and baseline characteristics of a randomized trial of diet and physical activity in ovarian cancer survivors. Gynecol Oncol. 2023 Jan 4;170:11-18. [Epub ahead of print] PubMed PMID: 36608382
• Davies KD, Smith LP, Guimaraes-Young A, Corr BR, Fisher CM, Guntupalli SR, Berning AA, Post MD, Pino D, Aisner DL, Wolsky RJ. Prospective Clinical Prognostication of Endometrial Carcinomas Based on Next-Generation Sequencing and Immunohistochemistry-Real-World Implementation and Results at a Tertiary Care Center. Int J Gynecol Pathol. 2023 Oct 4. [Epub ahead of print] PubMed PMID: 37922951
• Navi BB, Zhang C, Kaiser JH, Liao V, Cushman M, Kasner SE, Elkind MSV, Tagawa ST, Guntupalli SR, Gaudino MFL, Lee AYY, Khorana AA, Kamel H. Cancer and the Risk of Perioperative Arterial Ischemic Events. Eur Heart J Qual Care Clin Outcomes. 2023 Sep 26. [Epub ahead of print] PubMed PMID: 37757472
• Porragas-Paseiro HS, Guntupalli S, Xiong J, Greenwood A. A complete durable response of vaginal clear cell carcinoma with pembrolizumab: A case report. Gynecol Oncol Rep. 2023 Oct;49:101160. PubMed PMID: 37636492
• Hagemann IS, Deng W, Zaino RJ, Powell MA, Gunderson Jackson C, Cosgrove C, Mathews C, Pearl ML, Waggoner S, Ghebre R, Lele S, Guntupalli S, Secord AA, Ioffe O, Rasty G, Singh M, Soslow R, Creasman W, Mutch DG. Mixed clear cell/endometrioid and clear cell/serous carcinoma of the uterus are clinicopathologically similar to pure clear cell carcinoma: An NRG Oncology/Gynecologic Oncology Group (GOG-210) study of 311 women. Gynecol Oncol. 2023 Oct;177:38-45. PubMed PMID: 37634258
• Guntupalli S, Park P, Han DH, Zhang L, Yong XLH, Ringuet M, Blackmore DG, Jhaveri DJ, Koentgen F, Widagdo J, Kaang BK, Anggono V. Ubiquitination of the GluA1 Subunit of AMPA Receptors Is Required for Synaptic Plasticity, Memory, and Cognitive Flexibility. J Neurosci. 2023 Jul 26;43(30):5448-5457. PubMed PMID: 37419688
• Guntupalli SR, Spinosa D, Wethington S, Eskander R, Khorana AA. Prevention of venous thromboembolism in patients with cancer. BMJ. 2023 Jun 1;381:e072715. PubMed PMID: 37263632
• Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, Jeong AD, Guntupalli SR, Behbakht K, Gbaja V, Arnoult N, Chuong EB, Bitler BG. Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models. bioRxiv. 2023 Feb 23. PubMed PMID: 36865165
• Thomson CA, Crane TE, Miller A, Gold MA, Powell M, Bixel K, Van Le L, DiSilvestro P, Ratner E, Lele S, Guntupalli S, Huh W, Robertson SE, Modesitt S, Casey AC, Basen-Engquist K, Skiba M, Walker J, Kachnic L, Alberts DS. Lifestyle intervention in ovarian cancer enhanced survival (LIVES) study (NRG/GOG0225): Recruitment, retention and baseline characteristics of a randomized trial of diet and physical activity in ovarian cancer survivors. Gynecol Oncol. 2023 Mar;170:11-18. PubMed PMID: 36608382
• Schulte V, Persenaire C, Moroney MR, Guntupalli SR. Utilizing preoperative arterial embolization to minimize blood loss at time of vulvar sarcoma resection: A case report. Gynecol Oncol Rep. 2022 Dec;44:101089. PubMed PMID: 36388755
• Copeland LJ, Brady MF, Burger RA, Rodgers WH, Huang HQ, Cella D, O'Malley DM, Street DG, Tewari KS, Bender DP, Morris RT, Lowery WJ, Miller DS, Dewdney SB, Spirtos NM, Lele SB, Guntupalli S, Ueland FR, Glaser GE, Mannel RS, DiSaia PJ. Phase III Randomized Trial of Maintenance Taxanes Versus Surveillance in Women With Advanced Ovarian/Tubal/Peritoneal Cancer: A Gynecologic Oncology Group 0212:NRG Oncology Study. J Clin Oncol. 2022 Dec 10;40(35):4119-4128. PubMed PMID: 35759733
• Yamamoto TM, Webb PG, Davis DM, Baumgartner HK, Woodruff ER, Guntupalli SR, Neville M, Behbakht K, Bitler BG. Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors. Mol Cancer Ther. 2022 Apr 1;21(4):647-657. PubMed PMID: 35373300
• Levinson K, Beavis AL, Purdy C, Rositch AF, Viswanathan A, Wolfson AH, Kelly MG, Tewari KS, McNally L, Guntupalli SR, Ragab O, Lee YC, Miller DS, Huh WK, Wilkinson KJ, Spirtos NM, Le LV, Casablanca Y, Holman LL, Waggoner SE, Fader AN. Corrigendum to "Beyond Sedlis-A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis" [Gynecologic Oncology 162 (2021) 532-538]. Gynecol Oncol. 2021 Dec;163(3):616-617. PubMed PMID: 34654574
• Levinson K, Beavis AL, Purdy C, Rositch AF, Viswanathan A, Wolfson AH, Kelly MG, Tewari KS, McNally L, Guntupalli SR, Ragab O, Lee YC, Miller DS, Huh WK, Wilkinson KJ, Spirtos NM, Van Le L, Casablanca Y, Holman LL, Waggoner SE, Fader AN. Beyond Sedlis-A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis. Gynecol Oncol. 2021 Sep;162(3):532-538. PubMed PMID: 34217544
• Cantwell CJ, Moroney MR, Sheeder J, Guntupalli SR. Assessing Inequities in Cervical Cancer Quality of Care and Survival Related to Ethnicity and Socioeconomic Factors. J Low Genit Tract Dis. 2021 Jul 1;25(3):205-209. PubMed PMID: 34050109
• Guntupalli SR, Nout RA, Dreyer G. Highlights from the recent 2020 Annual Global IGCS Meeting. Gynecol Oncol. 2021 May;161(2):333-335. PubMed PMID: 33653610
• Gillen J, Miller A, Bell-McGuinn KM, Schilder RJ, Walker JL, Mathews CA, Duska LR, Guntupalli SR, O'Cearbhaill R, Hays J, Hagemann AR, Gray HJ, Gordon SW, Armstrong DK, Chen A, Fracasso PM, Aghajanian C, Moore KN. Post hoc analyses of GOG 9923: Does BRCA status affect toxicities?: An NRG oncology study. Gynecol Oncol. 2021 May;161(2):512-515. PubMed PMID: 33610319
• Hagemann IS, Deng W, Zaino RJ, Powell MA, Gunderson C, Cosgrove C, Mathews C, Pearl ML, Waggoner S, Ghebre R, Lele S, Guntupalli S, Secord AA, Ioffe O, Park K, Rasty G, Singh M, Soslow R, Creasman W, Mutch DG. The presence of an endometrioid component does not alter the clinicopathologic profile or survival of patients with uterine serous cancer: A gynecologic oncology group (GOG/NRG) study of 934 women. Gynecol Oncol. 2021 Mar;160(3):660-668. PubMed PMID: 33423806
• Kuroki L, Guntupalli SR. Treatment of epithelial ovarian cancer. BMJ. 2020 Nov 9;371:m3773. PubMed PMID: 33168565
• Glickman A, Brennecke A, Tayebnejad A, Matsuo K, Guntupalli SR, Sheeder J. Cost-effectiveness of apixaban for prevention of venous thromboembolic events in patients after gynecologic cancer surgery. Gynecol Oncol. 2020 Nov;159(2):476-482. PubMed PMID: 32854972
• Ross ME, Glickman A, Brennecke A, Tayebnejad A, Guntupalli SR. Adherence to postoperative thromboprophylactic medication among gynecologic oncology patients: A subanalysis. Gynecol Oncol. 2020 Sep;158(3):754-759. PubMed PMID: 32641236
• Guntupalli SR, Brennecke A, Behbakht K, Tayebnejad A, Breed CA, Babayan LM, Cheng G, Ramzan AA, Wheeler LJ, Corr BR, Lefkowits C, Sheeder J, Matsuo K, Flink D. Safety and Efficacy of Apixaban vs Enoxaparin for Preventing Postoperative Venous Thromboembolism in Women Undergoing Surgery for Gynecologic Malignant Neoplasm: A Randomized Clinical Trial. JAMA Netw Open. 2020 Jun 1;3(6):e207410. PubMed PMID: 32589230
• Wheeler LJ, Guntupalli SR. Female Sexual Dysfunction: Pharmacologic and Therapeutic Interventions. Obstet Gynecol. 2020 Jul;136(1):174-186. PubMed PMID: 32541291
• Monk BJ, Coleman RL, Moore KN, Herzog TJ, Secord AA, Matulonis UA, Slomovitz BM, Guntupalli SR, O'Malley DM. COVID-19 and ovarian cancer: Exploring alternatives to intravenous (IV) therapies. Gynecol Oncol. 2020 Jul;158(1):34-36. PubMed PMID: 32370991
• Chase D, Huang HQ, Monk BJ, Ramondetta LM, Penson RT, Gil K, Landrum LM, Leitao M, Oaknin A, Huh WK, Pulaski HL, Robison K, Guntupalli SR, Richardson D, Salani R, Sill MW, Wenzel LB, Tewari KS. Patient-reported outcomes at discontinuation of anti-angiogenesis therapy in the randomized trial of chemotherapy with bevacizumab for advanced cervical cancer: an NRG Oncology Group study. Int J Gynecol Cancer. 2020 May;30(5):596-601. PubMed PMID: 32114513
• Whitmore G, Ramzan A, Sheeder J, Guntupalli SR. African American women with advanced-stage ovarian cancer have worse outcomes regardless of treatment type. Int J Gynecol Cancer. 2020 Jul;30(7):1018-1025. PubMed PMID: 32107316
• Guntupalli SR. Hysterectomy in Residency Training: The New Numbers Game?. Obstet Gynecol. 2020 Feb;135(2):266-267. PubMed PMID: 31923080
• Moore KN, Miller A, Bell-McGuinn KM, Schilder RJ, Walker JL, O'Cearbhaill RE, Guntupalli SR, Armstrong DK, Hagemann AR, Gray HJ, Duska LR, Mathews CA, Chen A, O'Malley D, Gordon S, Fracasso PM, Aghajanian C. A phase I study of intravenous or intraperitoneal platinum based chemotherapy in combination with veliparib and bevacizumab in newly diagnosed ovarian, primary peritoneal and fallopian tube cancer. Gynecol Oncol. 2020 Jan;156(1):13-22. PubMed PMID: 31708167
• Guntupalli SR. Hysterectomy in Residency Training: The New Numbers Game?. Obstet Gynecol. 2020 Jan 9. [Epub ahead of print] PubMed PMID: 31923080
• Moore KN, Miller A, Bell-McGuinn KM, Schilder RJ, Walker JL, O'Cearbhaill RE, Guntupalli SR, Armstrong DK, Hagemann AR, Gray HJ, Duska LR, Mathews CA, Chen A, O'Malley D, Gordon S, Fracasso PM, Aghajanian C. A phase I study of intravenous or intraperitoneal platinum based chemotherapy in combination with veliparib and bevacizumab in newly diagnosed ovarian, primary peritoneal and fallopian tube cancer. Gynecol Oncol. 2020 Jan;156(1):13-22. PubMed PMID: 31708167
• Kuroki L, Guntupalli SR. Treatment of epithelial ovarian cancer. BMJ. 2020 Nov 9;371:m3773. PubMed PMID: 33168565
• Glickman A, Brennecke A, Tayebnejad A, Matsuo K, Guntupalli SR, Sheeder J. Cost-effectiveness of apixaban for prevention of venous thromboembolic events in patients after gynecologic cancer surgery. Gynecol Oncol. 2020 Nov;159(2):476-482. PubMed PMID: 32854972
• Ross ME, Glickman A, Brennecke A, Tayebnejad A, Guntupalli SR. Adherence to postoperative thromboprophylactic medication among gynecologic oncology patients: A subanalysis. Gynecol Oncol. 2020 Sep;158(3):754-759. PubMed PMID: 32641236
• Guntupalli SR, Brennecke A, Behbakht K, Tayebnejad A, Breed CA, Babayan LM, Cheng G, Ramzan AA, Wheeler LJ, Corr BR, Lefkowits C, Sheeder J, Matsuo K, Flink D. Safety and Efficacy of Apixaban vs Enoxaparin for Preventing Postoperative Venous Thromboembolism in Women Undergoing Surgery for Gynecologic Malignant Neoplasm: A Randomized Clinical Trial. JAMA Netw Open. 2020 Jun 1;3(6):e207410. PubMed PMID: 32589230
• Wheeler LJ, Guntupalli SR. Female Sexual Dysfunction: Pharmacologic and Therapeutic Interventions. Obstet Gynecol. 2020 Jul;136(1):174-186. PubMed PMID: 32541291
• Monk BJ, Coleman RL, Moore KN, Herzog TJ, Secord AA, Matulonis UA, Slomovitz BM, Guntupalli SR, O'Malley DM. COVID-19 and ovarian cancer: Exploring alternatives to intravenous (IV) therapies. Gynecol Oncol. 2020 Jul;158(1):34-36. PubMed PMID: 32370991
• Chase D, Huang HQ, Monk BJ, Ramondetta LM, Penson RT, Gil K, Landrum LM, Leitao M, Oaknin A, Huh WK, Pulaski HL, Robison K, Guntupalli SR, Richardson D, Salani R, Sill MW, Wenzel LB, Tewari KS. Patient-reported outcomes at discontinuation of anti-angiogenesis therapy in the randomized trial of chemotherapy with bevacizumab for advanced cervical cancer: an NRG Oncology Group study. Int J Gynecol Cancer. 2020 May;30(5):596-601. PubMed PMID: 32114513
• Whitmore G, Ramzan A, Sheeder J, Guntupalli SR. African American women with advanced-stage ovarian cancer have worse outcomes regardless of treatment type. Int J Gynecol Cancer. 2020 Jul;30(7):1018-1025. PubMed PMID: 32107316
• Guntupalli SR. Hysterectomy in Residency Training: The New Numbers Game?. Obstet Gynecol. 2020 Feb;135(2):266-267. PubMed PMID: 31923080
• Moore KN, Miller A, Bell-McGuinn KM, Schilder RJ, Walker JL, O'Cearbhaill RE, Guntupalli SR, Armstrong DK, Hagemann AR, Gray HJ, Duska LR, Mathews CA, Chen A, O'Malley D, Gordon S, Fracasso PM, Aghajanian C. A phase I study of intravenous or intraperitoneal platinum based chemotherapy in combination with veliparib and bevacizumab in newly diagnosed ovarian, primary peritoneal and fallopian tube cancer. Gynecol Oncol. 2020 Jan;156(1):13-22. PubMed PMID: 31708167
• Blake EA, Ross M, Ihenacho U, Figueroa L, Silverstein E, Flink D, Mendez-Ishizaki Y, Yessaian A, Brunette LL, Matsuo K, Cortessis VK, Guntupalli S, Roman L. Non-prescription cannabis use for symptom management amongst women with gynecologic malignancies. Gynecol Oncol Rep. 2019 Nov;30:100497. PubMed PMID: 31692541
• Wheeler LJ, Desanto K, Teal SB, Sheeder J, Guntupalli SR. Intrauterine Device Use and Ovarian Cancer Risk: A Systematic Review and Meta-analysis. Obstet Gynecol. 2019 Oct;134(4):791-800. PubMed PMID: 31503144
• Matsuo K, Cripe JC, Kurnit KC, Kaneda M, Garneau AS, Glaser GE, Nizam A, Schillinger RM, Kuznicki ML, Yabuno A, Yanai S, Garofalo DM, Suzuki J, St Laurent JD, Yen TT, Liu AY, Shida M, Kakuda M, Oishi T, Nishio S, Marcus JZ, Adachi S, Kurokawa T, Ross MS, Horowitz MP, Johnson MS, Kim MK, Melamed A, Machado KK, Yoshihara K, Yoshida Y, Enomoto T, Ushijima K, Satoh S, Ueda Y, Mikami M, Rimel BJ, Stone RL, Growdon WB, Okamoto A, Guntupalli SR, Hasegawa K, Shahzad MMK, Im DD, Frimer M, Gostout BS, Ueland FR, Nagao S, Soliman PT, Thaker PH, Wright JD, Roman LD. Recurrence, death, and secondary malignancy after ovarian conservation for young women with early-stage low-grade endometrial cancer. Gynecol Oncol. 2019 Oct;155(1):39-50. PubMed PMID: 31427143
• Urban RR, Ramzan AA, Doo DW, Sheeder J, Guntupalli SR. The perceptions of gynecologic oncology fellows on readiness for subspecialty training following OB/GYNRESIDENCY. Gynecol Oncol Rep. 2019 May;28:104-108. PubMed PMID: 30997375
• Moroney MR, Davies KD, Wilberger AC, Sheeder J, Post MD, Berning AA, Fisher C, Lefkowits C, Guntupalli SR, Behbakht K, Corr BR. Molecular markers in recurrent stage I, grade 1 endometrioid endometrial cancers. Gynecol Oncol. 2019 Jun;153(3):517-520. PubMed PMID: 30910249
• Brooks RA, Tritchler DS, Darcy KM, Lankes HA, Salani R, Sperduto P, Guntupalli S, DiSilvestro P, Kesterson J, Olawaiye AB, Moxley K, Waggoner S, Santin A, Rader JS, Kizer NT, Thaker PH, Powell MA, Mutch DG, Birrer MJ, Goodfellow PJ. GOG 8020/210: Risk stratification of lymph node metastasis, disease progression and survival using single nucleotide polymorphisms in endometrial cancer: An NRG oncology/gynecologic oncology group study. Gynecol Oncol. 2019 May;153(2):335-342. PubMed PMID: 30827726
• Guntupalli SR. What Is New in Venous Thromboembolism Prophylaxis in Gynecologic Surgery?: Best Articles From the Past Year. Obstet Gynecol. 2019 Mar;133(3):577-578. PubMed PMID: 30741818
• Rose PG, Java JJ, Salani R, Geller MA, Secord AA, Tewari KS, Bender DP, Mutch DG, Friedlander ML, Van Le L, Method MW, Hamilton CA, Lee RB, Wenham RM, Guntupalli SR, Markman M, Muggia FM, Armstrong DK, Bookman MA, Burger RA, Copeland LJ. Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma. Obstet Gynecol. 2019 Feb;133(2):245-254. PubMed PMID: 30633128
• Urban RR, Ramzan AA, Doo DW, Galan HL, Harper L, Omurtag K, Muffly TM, Sheeder J, Guntupalli SR. Fellow Perceptions of Residency Training in Obstetrics and Gynecology. J Surg Educ. 2019 Jan - Feb;76(1):93-98. PubMed PMID: 30093331
• Moroney MR, Flink D, Sheeder J, Blake EA, Carrubba AR, Fisher CM, Guntupalli SR. Radiation therapy is not an independent risk factor for decreased sexual function in women with gynecologic cancers. Rep Pract Oncol Radiother. 2018 Sep-Oct;23(5):331-336. PubMed PMID: 30127672
• Ramzan AA, Behbakht K, Corr BR, Sheeder J, Guntupalli SR. Minority Race Predicts Treatment by Non-gynecologic Oncologists in Women with Gynecologic Cancer. Ann Surg Oncol. 2018 Nov;25(12):3685-3691. PubMed PMID: 30105439
• Felix AS, Cohn DE, Brasky TM, Zaino R, Park K, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel CI, Boggess JF, Pearl ML, Ioffe OB, Randall ME, Brinton LA. Receipt of adjuvant endometrial cancer treatment according to race: an NRG Oncology/Gynecologic Oncology Group 210 Study. Am J Obstet Gynecol. 2018 Nov;219(5):459.e1-459.e11. PubMed PMID: 30096321
• Urban RR, Ramzan AA, Doo DW, Galan HL, Harper L, Omurtag K, Muffly TM, Sheeder J, Guntupalli SR. Fellow Perceptions of Residency Training in Obstetrics and Gynecology. J Surg Educ. 2018 Aug 7. [Epub ahead of print] PubMed PMID: 30093331
• Urban RR, Ramzan AA, Doo DW, Galan HL, Harper L, Omurtag K, Muffly TM, Sheeder J, Guntupalli SR. Fellow perceptions of residency training in obstetrics and gynecology. Am J Obstet Gynecol. 2018 Apr;218(4):461-462. PubMed PMID: 29353035
• Felix AS, Brasky TM, Cohn DE, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel C, Boggess JF, Pearl ML, Ioffe OB, Deng W, Miller DS, Brinton LA. Endometrial carcinoma recurrence according to race and ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study. Int J Cancer. 2018 Mar 15;142(6):1102-1115. PubMed PMID: 29063589
• Amini A, Yeh N, Jones BL, Bedrick E, Vinogradskiy Y, Rusthoven CG, Amini A, Purcell WT, Karam SD, Kavanagh BD, Guntupalli SR, Fisher CM. Perioperative Mortality in Nonelderly Adult Patients With Cancer: A Population-based Study Evaluating Health Care Disparities in the United States According to Insurance Status. Am J Clin Oncol. 2018 May;41(5):476-484. PubMed PMID: 27281264
• Guntupalli SR, Sheeder J, Ioffe Y, Tergas A, Wright JD, Davidson SA, Behbakht K, Flink DM. Sexual and Marital Dysfunction in Women With Gynecologic Cancer. Int J Gynecol Cancer. 2017 Jan 26. [Epub ahead of print] PubMed PMID: 28129243
• Brasky TM, Felix AS, Cohn DE, McMeekin DS, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel CI, Boggess JF, Pearl ML, Ioffe OB, Park KJ, Ali S, Brinton LA. Nonsteroidal Anti-inflammatory Drugs and Endometrial Carcinoma Mortality and Recurrence. J Natl Cancer Inst. 2017 Mar;109(3). PubMed PMID: 27986878
• Corr BR, Carrubba A, Sheeder J, Cheng G, Guntupalli SR. Histopathology Discrepancy of Preoperative Endometrial Sampling and Final Specimen: How Does This Influence Selective Lymph Node Dissection?. Int J Gynecol Cancer. 2017 Feb;27(2):297-301. PubMed PMID: 27870710
• Karisetty BC, Maitra S, Wahul AB, Musalamadugu A, Khandelwal N, Guntupalli S, Garikapati R, Jhansyrani T, Kumar A, Chakravarty S. Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones. Behav Brain Res. 2017 Feb 1;318:36-44. PubMed PMID: 27780721
• Felix AS, Brasky TM, Cohn DE, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel C, Boggess JF, Pearl ML, Ioffe OB, Deng W, Miller DS, Brinton LA. Endometrial carcinoma recurrence according to race and ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study. Int J Cancer. 2017 Oct 24. [Epub ahead of print] PubMed PMID: 29063589
• Matsuo K, Machida H, Horowitz MP, Shahzad MMK, Guntupalli SR, Roman LD, Wright JD. Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer. Am J Obstet Gynecol. 2017 Nov;217(5):580.e1-580.e10. PubMed PMID: 28666700
• Reyes HD, Miecznikowski J, Gonzalez-Bosquet J, Devor EJ, Zhang Y, Thiel KW, Samuelson MI, McDonald M, Stephan JM, Hanjani P, Guntupalli S, Tewari KS, Backes F, Ramirez N, Fleming GF, Filiaci V, Birrer MJ, Leslie KK. High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study. Gynecol Oncol. 2017 Aug;146(2):247-253. PubMed PMID: 28532857
• Creasman WT, Ali S, Mutch DG, Zaino RJ, Powell MA, Mannel RS, Backes FJ, DiSilvestro PA, Argenta PA, Pearl ML, Lele SB, Guntupalli SR, Waggoner S, Spirtos N, Boggess JF, Edwards RP, Filiaci VL, Miller DS. Surgical-pathological findings in type 1 and 2 endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study on GOG-210 protocol. Gynecol Oncol. 2017 Jun;145(3):519-525. PubMed PMID: 28392124
• Guntupalli S, Jang SE, Zhu T, Huganir RL, Widagdo J, Anggono V. GluA1 subunit ubiquitination mediates amyloid-ß-induced loss of surface a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. J Biol Chem. 2017 May 19;292(20):8186-8194. PubMed PMID: 28377502
• Brasky TM, Felix AS, Cohn DE, McMeekin DS, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel CI, Boggess JF, Pearl ML, Ioffe OB, Park KJ, Ali S, Brinton LA. Nonsteroidal Anti-inflammatory Drugs and Endometrial Carcinoma Mortality and Recurrence. J Natl Cancer Inst. 2017 Mar 1;109(3):1-10. PubMed PMID: 28376204
• Guntupalli SR, Sheeder J, Ioffe Y, Tergas A, Wright JD, Davidson SA, Behbakht K, Flink DM. Sexual and Marital Dysfunction in Women With Gynecologic Cancer. Int J Gynecol Cancer. 2017 Mar;27(3):603-607. PubMed PMID: 28129243
• Corr BR, Carrubba A, Sheeder J, Cheng G, Guntupalli SR. Histopathology Discrepancy of Preoperative Endometrial Sampling and Final Specimen: How Does This Influence Selective Lymph Node Dissection?. Int J Gynecol Cancer. 2017 Feb;27(2):297-301. PubMed PMID: 27870710
• Karisetty BC, Maitra S, Wahul AB, Musalamadugu A, Khandelwal N, Guntupalli S, Garikapati R, Jhansyrani T, Kumar A, Chakravarty S. Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones. Behav Brain Res. 2017 Feb 1;318:36-44. PubMed PMID: 27780721
• Backes CH, Bonachea EM, Rivera BK, Reynolds MM, Kovalchin CE, Reber KM, Ball MK, Sutsko R, Guntupalli SR, Smith CV, Mahan JD, Carbajal MM. Preparedness of pediatric residents for fellowship: a survey of US neonatal-perinatal fellowship program directors. J Perinatol. 2016 Dec;36(12):1132-1137. PubMed PMID: 27684422
• Carlson M, Guntupalli S, Ko E, Wright JD. SGO Health Policy and Socioeconomic Committee: Current and future efforts of the Future of Physician Payment Reform Taskforce and the Legislative and Regulatory Affairs Taskforce. Gynecol Oncol. 2016 Sep;142(3):385-7. PubMed PMID: 27287506
• Amini A, Yeh N, Jones BL, Bedrick E, Vinogradskiy Y, Rusthoven CG, Amini A, Purcell WT, Karam SD, Kavanagh BD, Guntupalli SR, Fisher CM. Perioperative Mortality in Nonelderly Adult Patients With Cancer: A Population-based Study Evaluating Health Care Disparities in the United States According to Insurance Status. Am J Clin Oncol. 2016 Jun 8. [Epub ahead of print] PubMed PMID: 27281264
• Blake EA, Sheeder J, Behbakht K, Guntupalli SR, Guy MS. Factors Impacting Use of Robotic Surgery for Treatment of Endometrial Cancer in the United States. Ann Surg Oncol. 2016 Oct;23(11):3744-3748. PubMed PMID: 27172774
• Amini A, Jones BL, Yeh N, Guntupalli SR, Kavanagh BD, Karam SD, Fisher CM. Disparities in disease presentation in the four screenable cancers according to health insurance status. Public Health. 2016 Sep;138:50-6. PubMed PMID: 27091437
• Guntupalli S, Widagdo J, Anggono V. Amyloid-ß-Induced Dysregulation of AMPA Receptor Trafficking. Neural Plast. 2016;2016:3204519. PubMed PMID: 27073700
• Carrubba AR, Corr BR, Sheeder J, Guntupalli SR. Evaluation of Preoperative Chest Imaging in Low-Risk Endometrial Cancer Patients. Int J Gynecol Cancer. 2016 Feb;26(2):348-53. PubMed PMID: 26807565
• Guntupalli SR. In Reply. Obstet Gynecol. 2016 Jan;127(1):161. PubMed PMID: 26695564
• Doo DW, Guy MS, Behbakht K, Davidson SA, Sheeder J, Guntupalli SR. Association Between Preoperative Chemotherapy and Postoperative Complications in Patients Undergoing Surgery for Ovarian Cancer. Ann Surg Oncol. 2016 Mar;23(3):968-74. PubMed PMID: 26542594
• Guy MS, Sheeder J, Behbakht K, Wright JD, Guntupalli SR. Comparative outcomes in older and younger women undergoing laparotomy or robotic surgical staging for endometrial cancer. Am J Obstet Gynecol. 2016 Mar;214(3):350.e1-350.e10. PubMed PMID: 26433173
• Backes CH, Bonachea EM, Rivera BK, Reynolds MM, Kovalchin CE, Reber KM, Ball MK, Sutsko R, Guntupalli SR, Smith CV, Mahan JD, Carbajal MM. Preparedness of pediatric residents for fellowship: a survey of US neonatal-perinatal fellowship program directors. J Perinatol. 2016 Dec;36(12):1132-1137. PubMed PMID: 27684422
• Carlson M, Guntupalli S, Ko E, Wright JD. SGO Health Policy and Socioeconomic Committee: Current and future efforts of the Future of Physician Payment Reform Taskforce and the Legislative and Regulatory Affairs Taskforce. Gynecol Oncol. 2016 Sep;142(3):385-7. PubMed PMID: 27287506
• Amini A, Yeh N, Jones BL, Bedrick E, Vinogradskiy Y, Rusthoven CG, Amini A, Purcell WT, Karam SD, Kavanagh BD, Guntupalli SR, Fisher CM. Perioperative Mortality in Nonelderly Adult Patients With Cancer: A Population-based Study Evaluating Health Care Disparities in the United States According to Insurance Status. Am J Clin Oncol. 2016 Jun 8. [Epub ahead of print] PubMed PMID: 27281264
• Blake EA, Sheeder J, Behbakht K, Guntupalli SR, Guy MS. Factors Impacting Use of Robotic Surgery for Treatment of Endometrial Cancer in the United States. Ann Surg Oncol. 2016 Oct;23(11):3744-8. PubMed PMID: 27172774
• Amini A, Jones BL, Yeh N, Guntupalli SR, Kavanagh BD, Karam SD, Fisher CM. Disparities in disease presentation in the four screenable cancers according to health insurance status. Public Health. 2016 Sep;138:50-6. PubMed PMID: 27091437
• Guntupalli S, Widagdo J, Anggono V. Amyloid-ß-Induced Dysregulation of AMPA Receptor Trafficking. Neural Plast. 2016;2016:3204519. PubMed PMID: 27073700
• Carrubba AR, Corr BR, Sheeder J, Guntupalli SR. Evaluation of Preoperative Chest Imaging in Low-Risk Endometrial Cancer Patients. Int J Gynecol Cancer. 2016 Feb;26(2):348-53. PubMed PMID: 26807565
• Guntupalli SR. In Reply. Obstet Gynecol. 2016 Jan;127(1):161. PubMed PMID: 26695564
• Doo DW, Guy MS, Behbakht K, Davidson SA, Sheeder J, Guntupalli SR. Association Between Preoperative Chemotherapy and Postoperative Complications in Patients Undergoing Surgery for Ovarian Cancer. Ann Surg Oncol. 2016 Mar;23(3):968-74. PubMed PMID: 26542594
• Guy MS, Sheeder J, Behbakht K, Wright JD, Guntupalli SR. Comparative outcomes in older and younger women undergoing laparotomy or robotic surgical staging for endometrial cancer. Am J Obstet Gynecol. 2016 Mar;214(3):350.e1-350.e10. PubMed PMID: 26433173
• Carrubba AR, Corr BR, Sheeder J, Guntupalli SR. Evaluation of Preoperative Chest Imaging in Low-Risk Endometrial Cancer Patients. Int J Gynecol Cancer. 2016 Feb;26(2):348-53. PubMed PMID: 26807565
• Guntupalli SR. In Reply. Obstet Gynecol. 2016 Jan;127(1):161. PubMed PMID: 26695564
• Doo DW, Guy MS, Behbakht K, Davidson SA, Sheeder J, Guntupalli SR. Association Between Preoperative Chemotherapy and Postoperative Complications in Patients Undergoing Surgery for Ovarian Cancer. Ann Surg Oncol. 2015 Nov 5. [Epub ahead of print] PubMed PMID: 26542594
• Guy MS, Sheeder J, Behbakht K, Wright JD, Guntupalli SR. Comparative outcomes in older and younger women undergoing laparotomy or robotic surgical staging for endometrial cancer. Am J Obstet Gynecol. 2015 Nov 17. [Epub ahead of print] PubMed PMID: 26433173
• Guntupalli SR, Doo DW, Guy M, Sheeder J, Omurtag K, Kondapalli L, Valea F, Harper L, Muffly TM. Preparedness of Obstetrics and Gynecology Residents for Fellowship Training. Obstet Gynecol. 2015 Sep;126(3):559-68. PubMed PMID: 26244537
• Doo DW, Powell M, Novetsky A, Sheeder J, Guntupalli SR. Preparedness of Ob/Gyn residents for fellowship training in gynecologic oncology. Gynecol Oncol Rep. 2015 Apr;12:55-60. PubMed PMID: 26076160
• Blake EA, Cheng G, Post MD, Guntupalli S. Cotyledonoid dissecting leiomyoma with adipocytic differentiation: A case report. Gynecol Oncol Rep. 2015 Jan;11:7-9. PubMed PMID: 26076084
• Lamale-Smith LM, Moore GS, Guntupalli SR, Scott JB. Maternal-fetal transfer of anti-N-methyl-D-aspartate receptor antibodies. Obstet Gynecol. 2015 May;125(5):1056-8. PubMed PMID: 25710615
• Doo DW, Guntupalli SR, Corr BR, Sheeder J, Davidson SA, Behbakht K, Jarrett MJ, Guy MS. Comparative Surgical Outcomes for Endometrial Cancer Patients 65 Years Old or Older Staged With Robotics or Laparotomy. Ann Surg Oncol. 2015 Oct;22(11):3687-94. PubMed PMID: 25672563
• Hopkins M, Richmond A, Cheng G, Sheeder J, Post M Davidson S, Spillman M, Guntupalli SR Lymphovascular Space Invasion in Robotic Surgery for Uterine Cancer Preliminary accepted for Publication: Journal of Laparoendoscopic Surgery
• Guy MS, Cheng G, Sheeder J, Post M, Behbakht K, Davidson S, Spillman M, Guntupalli SR Outcomes of women with atypical glandular cells on pre-operative cervical cytology and endometrial cancer. Int J Gynecol Cancer 2014 24(2):266-71 PMID: 24401985
• Tergas AI, Havrilesky LJ, Fader A, Guntupalli SR, Huh WK, Massad LS, Rimel BJ Cost Analysis of Colposcopy for Abnormal Cytology in Post-treatment Surveillance for Cervical Cancer Gynecol Oncol 2013 PMID:23747836
• Lee JL Guntupalli SR Diamond J Theodorescu D Behbakht K Kim YC Retrospective analysis of survival improvement by molecular biomarker-based personalized chemotherapy for recurrent ovarian cancer PLOS One 2014 9(2):86532 PMID: 24505259
• Wilms' Tumor 1 Protein and Estrogen Receptor Beta Expression are Associated with Poor Outcomes in Uterine Carcinosarcoma. Guntupalli SR, Cao D, Shroff R, Gao F, Menias C, Stewart Massad L, Powell MA, Mutch DG, Thaker PH. Ann Surg Oncol. 2013

Professional Memberships

• American Association of Physicians of Indian Origin (AAPI) - Medical Students, Residents and Fellows Section, President Elect June 2006 - May 2007
• Governmental Affairs Committee, Society of Gynecologic Oncologists (SGO), Member
• American Congress of Obstetrics and Gynecology, Member
• Society of Gynecologic Oncologists, Candidate Member
• American College of Surgeons, Member

Practice Locations

• University of Colorado Hospital
• Denver Health Medical Center
• UCHealth Highlands Ranch Hospital

• University of Colorado Cancer Center

Specialty Information

• Gynecologic Oncology, Board Certification

• Cancers - Cervical Cancer
• Cancers - Chemotherapy
• Cancers - Gynecologic Cancer
• Cancers - Ovarian Cancer
• Cancers - Uterine Cancer
• Surgery - Robotic Surgery
• Women's Health - Endometriosis
• Cancers
• Women's Health
• Surgery