My reserach activities are focused on investigating the underyling causes and treatment of inflammatory bowel disease (IBD). Specicially, I am interested in new blood vessel formation within the intestines (angiogenesis) and its contributions to gut inflammation.
Publications
Gao RY, Shearn CT, Orlicky DJ, Battista KD, Alexeev EE, Cartwright IM, Lanis JM, Kostelecky RE, Ju C, Colgan SP, Fennimore BP. Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis. Mucosal Immunol. 2020 Oct 1. [Epub ahead of print] PubMed PMID: 33004979
Scott FI, Hans AK, Gerich ME, Fennimore B, Mamtani R, Vajravelu RK, Lewis JD. Identification of the Most Effective Position for Ustekinumab in Treatment Algorithms for Crohn's Disease. Clin Gastroenterol Hepatol. 2020 Aug 12. [Epub ahead of print] PubMed PMID: 32801006
deZoeten EF, Battista KD, Colson SB, Lovell MA, Kessler BE, Isfort RW, Fennimore BP, Onyiah JC, Kao DJ, Yeckes A, Keely S, Murray M, Hoffenberg EJ, Colgan SP, Gerich ME. Markers of Hypoxia Correlate with Histologic and Endoscopic Severity of Colitis in Inflammatory Bowel Disease. Hypoxia (Auckl). 2020;8:1-12. PubMed PMID: 32104717
Coleman SL, Neff CP, Li SX, Armstrong AJS, Schneider JM, Sen S, Fennimore B, Campbell TB, Lozupone CA, Palmer BE. Can gut microbiota of men who have sex with men influence HIV transmission?. Gut Microbes. 2020 May 3;11(3):610-619. PubMed PMID: 32036739
Scott FI, Luo M, Shah Y, Lasch K, Vajravelu RK, Mamtani R, Fennimore B, Gerich ME, Lewis JD. Identification of the Most Cost-effective Position of Vedolizumab Among the Available Biologic Drugs for the Treatment of Ulcerative Colitis. J Crohns Colitis. 2020 Jun 19;14(5):575-587. PubMed PMID: 31901085
Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2020 Mar;13(2):230-244. PubMed PMID: 31792360
Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2019 Dec 2. [Epub ahead of print] PubMed PMID: 31792360
Shearn CT, Fennimore B, Orlicky DJ, Gao YR, Saba LM, Battista KD, Aivazidis S, Assiri M, Harris PS, Michel C, Merrill GF, Schmidt EE, Colgan SP, Petersen DR. Cholestatic liver disease results increased production of reactive aldehydes and an atypical periportal hepatic antioxidant response. Free Radic Biol Med. 2019 Nov 1;143:101-114. PubMed PMID: 31377417
Regner EH, Ohri N, Stahly A, Gerich ME, Fennimore BP, Ir D, Jubair WK, Görg C, Siebert J, Robertson CE, Caplan L, Frank DN, Kuhn KA. Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota. Arthritis Res Ther. 2018 Jul 20;20(1):149. PubMed PMID: 30029674
Glover LE, Fennimore B, Wingfield M. Inflammatory Bowel Disease: Influence and Implications in Reproduction. Inflamm Bowel Dis. 2016 Nov;22(11):2724-2732. PubMed PMID: 27537054
Kriss M, Kaplan J, Fennimore B. A rare cause of postprandial abdominal pain and nausea. Gastroenterology. 2015 Nov;149(6):e11-2. PubMed PMID: 26433105
Weissmüller T, Glover LE, Fennimore B, Curtis VF, MacManus CF, Ehrentraut SF, Campbell EL, Scully M, Grove BD, Colgan SP. HIF-dependent regulation of AKAP12 (gravin) in the control of human vascular endothelial function. FASEB J. 2014 Jan;28(1):256-64. PubMed PMID: 24029533
Weissmüller T, Glover LE, Fennimore B, Curtis VF, MacManus CF, Ehrentraut SF, Campbell EL, Scully M, Grove BD, Colgan SP. HIF-dependent regulation of AKAP12 (gravin) in the control of human vascular endothelial function. FASEB J. 2014 Jan;28(1):256-64. PubMed PMID: 24029533
Colgan SP, Fennimore B, Ehrentraut SF. Adenosine and gastrointestinal inflammation. J Mol Med (Berl). 2013 Feb;91(2):157-64. PubMed PMID: 23296303
Austin GL, Fennimore B, Ahnen DJ. Can colonoscopy remain cost-effective for colorectal cancer screening? The impact of practice patterns and the Will Rogers phenomenon on costs. Am J Gastroenterol. 2013 Mar;108(3):296-301. PubMed PMID: 23208273
Clinical Interests
My main clinical interest is in the medical and endoscopic management of patients with Inflammatory Bowel Disease (IBD) including Crohn's Disease and Ulcerative Colitis. The UCH Crohn's and Colitis Center utilizes a multi-disciplinary team of IBD focused clinicians and support staff (nutritionsit, social workers, and nurse clinical coordinators) to provide cutting edge care for our IBD patients.
Care Philosophy
Utilizing a multidisciplinary and comprehensive diagnostic approach combined with cutting edge treatment options, I strive to provide the best healthcare possible for my patients.
Personal Interests
In my spare time, I enjoy spending time with my family, snowboarding, and endurance sports such as triathlon, cycling, and long distance running.
General Information
Medical Schools:
MD, Wake Forest University School of Medicine
(2006)
Undergraduate Schools:
BS, University of North Carolina–Chapel Hill (NC)
(2002)
Internships:
University of Colorado (University Hospital) Program
(2007)
Residency Programs:
University of Colorado (University Hospital) Program, Internal Medicine (2009)
Fellowships:
University of Colorado (University Hospital) Program, Gastroenterology
(2012)