Colleen Julian, PhD

Publications

• Wiegel RE, Baker K, Calderon-Toledo C, Gomez R, Gutiérrez-Cortez S, Houck JA, Larrea A, Lazo-Vega L, Moore LG, Pisc J, Toledo-Jaldin L, Julian CG. Impaired maternal central hemodynamics precede the onset of vascular disorders of pregnancy at high altitude. Am J Physiol Heart Circ Physiol. 2025 Jan 1;328(1):H174-H185. PubMed PMID: 39657993
• Moore LG, Julian CG, Lorca RA, Cioffi-Ragan D, Gumina D, Hobbins JC. Does Hypoxia Prompt Fetal Brain-Sparing in the Absence of Fetal Growth Restriction?. Physiol Res. 2024 Nov 29;73(S2):S487-S493. PubMed PMID: 39589298
• Murphy M, Fallahi S, Dumolt JH, Houck JA, Vaughan OR, Moore LG, Julian CG, Rosario FJ, Powell TL, Jansson T, Lorca RA. Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero. bioRxiv. 2024 Oct 30. PubMed PMID: 39345365
• Moore LG, Lorca RA, Gumina DL, Wesolowski SR, Reisz JA, Cioffi-Ragan D, Houck JA, Banerji S, Euser AG, D'Alessandro A, Hobbins JC, Julian CG. Maternal AMPK pathway activation with uterine artery blood flow and fetal growth maintenance during hypoxia. Am J Physiol Heart Circ Physiol. 2024 Oct 1;327(4):H778-H792. PubMed PMID: 39028630
• Collins HE, Alexander BT, Care AS, Davenport MH, Davidge ST, Eghbali M, Giussani DA, Hoes MF, Julian CG, LaVoie HA, Olfert IM, Ozanne SE, Bytautiene Prewit E, Warrington JP, Zhang L, Goulopoulou S. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum. Am J Physiol Heart Circ Physiol. 2024 Jul 1;327(1):H191-H220. PubMed PMID: 38758127
• Heath-Freudenthal A, Estrada A, von Alvensleben I, Julian CG. Surviving birth at high altitude. J Physiol. 2024 Nov;602(21):5463-5473. PubMed PMID: 38520695
• O'Brien KA, Gu W, Houck JA, Holzner LMW, Yung HW, Armstrong JL, Sowton AP, Baxter R, Darwin PM, Toledo-Jaldin L, Lazo-Vega L, Moreno-Aramayo AE, Miranda-Garrido V, Shortt JA, Matarazzo CJ, Yasini H, Burton GJ, Moore LG, Simonson TS, Murray AJ, Julian CG. Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia. Hypertension. 2024 Feb;81(2):319-329. PubMed PMID: 38018457
• Jankowski CM, Konigsberg IR, Wilson MP, Sun J, Brown TT, Julian CG, Erlandson KM. Skeletal muscle DNA methylation: Effects of exercise and HIV. Aging Cell. 2024 Jan;23(1):e14025. PubMed PMID: 37920126
• O'Brien KA, Gu W, Houck JA, Holzner LMW, Wa Yung H, Armstrong JL, Sowton AP, Baxter R, Darwin PM, Toledo-Jaldin L, Lazo-Vega L, Moreno-Aramayo A, Miranda-Garrido V, Shortt JA, Matarazzo CJ, Yasini H, Burton GJ, Moore LG, Simonson TS, Murray AJ, Julian CG. Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia. Hypertension. 2023 Nov 29. [Epub ahead of print] PubMed PMID: 38018457
• Jankowski CM, Konigsberg IR, Wilson MP, Sun J, Brown TT, Julian CG, Erlandson KM. Skeletal muscle DNA methylation: Effects of exercise and HIV. Aging Cell. 2023 Nov 3;:e14025. [Epub ahead of print] PubMed PMID: 37920126
• Toledo-Jaldin L, Lazo-Vega L, Grau L, Lawrence I, Larrea-Alvarado A, Mizutani R, Rocabado S, Vasan V, Sammel M, Julian CG, Moore LG. Increased adherence to ACOG diagnostic guidelines for HDP following a workshop in Bolivia, a LMIC. Pregnancy Hypertens. 2023 Dec;34:19-26. PubMed PMID: 37778281
• Julian CG. Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for High Altitude Medicine & Biology. High Alt Med Biol. 2023 Sep;24(3):157. PubMed PMID: 37722012
• Julian CG, Houck JA, Fallahi S, Lazo-Vega L, Matarazzo CJ, Diamond B, Miranda-Garrido V, Krause BJ, Moore LG, Shortt JA, Toledo-Jaldin L, Lorca RA. Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies. Physiol Genomics. 2023 Sep 1;55(9):357-367. PubMed PMID: 37458464
• Kyllo HM, Wang D, Lorca RA, Julian CG, Moore LG, Wilkening RB, Rozance PJ, Brown LD, Wesolowski SR. Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency. Am J Physiol Endocrinol Metab. 2023 Jun 1;324(6):E556-E568. PubMed PMID: 37126847
• Heath-Freudenthal A, Toledo-Jaldin L, von Alvensleben I, Lazo-Vega L, Mizutani R, Stalker M, Yasini H, Mendizabal F, Dorado Madera J, Mundo W, Castro-Monrroy M, Houck JA, Moreno-Aramayo A, Miranda-Garrido V, Su EJ, Giussani DA, Abman SH, Moore LG, Julian CG. Vascular Disorders of Pregnancy Increase Susceptibility to Neonatal Pulmonary Hypertension in High-Altitude Populations. Hypertension. 2022 Jun;79(6):1286-1296. PubMed PMID: 35437031
• Lazo-Vega L, Toledo-Jaldin L, Badner A, Barriga-Vera JL, Castro-Monrroy M, Euser AG, Larrea-Alvarado A, Lawrence I, Mérida C, Mizutani R, Pérez Y, Rocabado S, Vargas M, Vasan V, Julian CG, Moore LG. ACOG and local diagnostic criteria for hypertensive disorders of pregnancy (HDP) in La Paz-El Alto, Bolivia: A retrospective case-control study. Lancet Reg Health Am. 2022 May;9. PubMed PMID: 35719175
• Yu JJ, Non AL, Heinrich EC, Gu W, Alcock J, Moya EA, Lawrence ES, Tift MS, O'Brien KA, Storz JF, Signore AV, Khudyakov JI, Milsom WK, Wilson SM, Beall CM, Villafuerte FC, Stobdan T, Julian CG, Moore LG, Fuster MM, Stokes JA, Milner R, West JB, Zhang J, Shyy JY, Childebayeva A, Vázquez-Medina JP, Pham LV, Mesarwi OA, Hall JE, Cheviron ZA, Sieker J, Blood AB, Yuan JX, Scott GR, Rana BK, Ponganis PJ, Malhotra A, Powell FL, Simonson TS. Time Domains of Hypoxia Responses and -Omics Insights. Front Physiol. 2022;13:885295. PubMed PMID: 36035495
• Moore LG, Wesolowski SR, Lorca RA, Murray AJ, Julian CG. Why is human uterine artery blood flow during pregnancy so high?. Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1;323(5):R694-R699. PubMed PMID: 36094446
• Fallahi S, Houck JA, Euser AG, Julian CG, Moore LG, Lorca RA. High altitude differentially modulates potassium channel-evoked vasodilatation in pregnant human myometrial arteries. J Physiol. 2022 Oct 26. [Epub ahead of print] PubMed PMID: 36286320
• Mundo W, Toledo-Jaldin L, Heath-Freudenthal A, Huayacho J, Lazo-Vega L, Larrea-Alvarado A, Miranda-Garrido V, Mizutani R, Moore LG, Moreno-Aramayo A, Gomez R, Gutierrez P, Julian CG. Is Maternal Cardiovascular Performance Impaired in Altitude-Associated Fetal Growth Restriction?. High Alt Med Biol. 2022 Dec 2. PubMed PMID: 36472463
• Lorca RA, Julian CG, Moore LG. Differential Effects of High-Altitude Residence on Potassium Channel Myometrial Vascular Responses. Reprod Sci. 2022 Mar;29(Suppl 1):1-335.
• Armstrong J, O’Brien K, Knapton A, Sowton A, Lorca RA, Toledo-Jaldin L, Julian CG, Moore LG, Murray A. Mitochondrial Respiratory Function in Placentas from High Altitude Pregnancy. Reprod Sci. 2022 Mar;29(Suppl 1):1-335.
• Kichula K, Song J, Toledo-Jaldin L,Houck JA, Moore LG, Norman PJ, Prchal JT and CG Julian. A Novel NF-?B Variant Associated with Preeclampsia and Reduced Birth Weight in High-Altitude Andeans. Reprod Sci. 2022 Mar;29(Suppl 1):1-335
• Houck JA, Diamond B, Matarazzo C, Lorca RA, Julian CG. Reduced Ion Channel Expression in Preeclamptic High-Altitude Pregnancies. Reprod Sci. 2022 Mar;29(Suppl 1):1-335
• Reyes LM, Usselman CW, Khurana R, Chari RS, Stickland MK, Davidge ST, Julian CG, Steinback CD, Davenport MH. Preeclampsia is not associated with elevated muscle sympathetic reactivity. J Appl Physiol (1985). 2021 Jan 1;130(1):139-148. PubMed PMID: 33211599
• Jones AK, Rozance PJ, Brown LD, Lorca RA, Julian CG, Moore LG, Limesand SW, Wesolowski SR. Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia. Physiol Rep. 2021 Sep;9(18):e15033. PubMed PMID: 34558219
• Lorca RA, Houck JA, Laurent LC, Matarazzo CJ, Baker K, Horii M, Nelson KK, Bales ES, Euser AG, Parast MM, Moore LG, Julian CG. High altitude regulates the expression of AMPK pathways in human placenta. Placenta. 2021 Jan 15;104:267-276. PubMed PMID: 33472134
• Mundo W, Wolfson G, Moore LG, Houck JA, Park D, Julian CG. Hypoxia-induced inhibition of mTORC1 activity in the developing lung: a possible mechanism for the developmental programming of pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H980-H990. PubMed PMID: 33416457
• Reyes LM, Usselman CW, Khurana R, Chari RS, Stickland MK, Davidge ST, Julian CG, Steinback CD, Davenport MH. Preeclampsia is not associated with elevated muscle sympathetic reactivity. J Appl Physiol (1985). 2021 Jan 1;130(1):139-148. PubMed PMID: 33211599
• Society for Reproductive Investigation, Boston, MA. Vascular disorders of pregnancy increase susceptibility to neonatal and infantile pulmonary hypertension in high-altitude populations. Heath A, Toledo-Jaldin L, von Alvensleben I, Lazo Vega L, Yasini H, Dorado Madera J, Stalker M, Houck JA, Moore LG, Julian CG.
• Society for Reproductive Investigation, Boston, MA. Maternal obesity during mouse pregnancy reduces resistance artery vasodilator responses in adult offspring. Houck JA, Dumolt JH, Vaughan OR, Powell TL, Jansson T, Moore LG, Julian CG, Lorca RA.
• Society for Reproductive Investigation, Boston, MA. ACOG guidelines identify more at-risk pregnancy but not more adverse outcomes in Bolivia. Lazo-Vega L, Toledo-Jaldin L, Larrea A, Julian CG, Moore LG.
• Grant I, Soria R, Julian CG, Vargas E, Moore LG, Aiken CE, Giussani DA. Parental ancestry and risk of early pregnancy loss at high altitude. FASEB J. 2020 Oct;34(10):13741-13749. PubMed PMID: 32856356
• Lane SL, Houck JA, Doyle AS, Bales ES, Lorca RA, Julian CG, Moore LG. AMP-activated protein kinase activator AICAR attenuates hypoxia-induced murine fetal growth restriction in part by improving uterine artery blood flow. J Physiol. 2020 Sep;598(18):4093-4105. PubMed PMID: 32592403
• Lorca RA, Matarazzo CJ, Bales ES, Houck JA, Orlicky DJ, Euser AG, Julian CG, Moore LG. AMPK activation in pregnant human myometrial arteries from high-altitude and intrauterine growth-restricted pregnancies. Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H203-H212. PubMed PMID: 32502374
• Bailey B, Euser AG, Bol KA, Julian CG, Moore LG. High-altitude residence alters blood-pressure course and increases hypertensive disorders of pregnancy. J Matern Fetal Neonatal Med. 2020 Mar 30;:1-8. [Epub ahead of print] PubMed PMID: 32228111
• Lamale-Smith LM, Gumina DL, Kramer AW, Browne VA, Toledo-Jaldin L, Julian CG, Winn VD, Moore LG. Uteroplacental Ischemia Is Associated with Increased PAPP-A2. Reprod Sci. 2020 Feb;27(2):529-536. PubMed PMID: 31994005
• Lane SL, Doyle AS, Bales ES, Houck JA, Lorca RA, Moore LG, Julian CG. Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy. FASEB J. 2020 Mar;34(3):4283-4292. PubMed PMID: 31970838
• Lane SL, Doyle AS, Bales ES, Lorca RA, Julian CG, Moore LG. Increased uterine artery blood flow in hypoxic murine pregnancy is not sufficient to prevent fetal growth restriction†. Biol Reprod. 2020 Mar 13;102(3):660-670. PubMed PMID: 31711123
• Vaughan OR, Thompson F, Lorca RA, Julian CG, Powell TL, Moore LG, Jansson T. Effect of high altitude on human placental amino acid transport. J Appl Physiol (1985). 2020 Jan 1;128(1):127-133. PubMed PMID: 31804891
• Lane SL, Doyle AS, Bales ES, Lorca RA, Julian CG, Moore LG. Increased uterine artery blood flow in hypoxic murine pregnancy is not sufficient to prevent fetal growth restriction. Biol Reprod. 2019 Nov 11. [Epub ahead of print] PubMed PMID: 31711123
• Bailey BA, Donnelly M, Bol K, Moore LG, Julian CG. High Altitude Continues to Reduce Birth Weights in Colorado. Matern Child Health J. 2019 Nov;23(11):1573-1580. PubMed PMID: 31243627
• Steinback CD, Fraser GM, Usselman CW, Reyes LM, Julian CG, Stickland MK, Chari RS, Khurana R, Davidge ST, Davenport MH. Blunted sympathetic neurovascular transduction during normotensive pregnancy. J Physiol. 2019 Jul;597(14):3687-3696. PubMed PMID: 31106429
• Toledo-Jaldin L, Bull S, Contag S, Escudero C, Gutierrez P, Heath A, Roberts JM, Scandlyn J, Julian CG, Moore LG. Critical barriers for preeclampsia diagnosis and treatment in low-resource settings: An example from Bolivia. Pregnancy Hypertens. 2019 Apr;16:139-144. PubMed PMID: 31056149
• Lane SL, Dodson RB, Doyle AS, Park H, Rathi H, Matarrazo CJ, Moore LG, Lorca RA, Wolfson GH, Julian CG. Pharmacological activation of peroxisome proliferator-activated receptor ? (PPAR-?) protects against hypoxia-associated fetal growth restriction. FASEB J. 2019 Aug;33(8):8999-9007. PubMed PMID: 31039323
• Lorca RA, Lane SL, Bales ES, Nsier H, Yi H, Donnelly MA, Euser AG, Julian CG, Moore LG. High Altitude Reduces NO-Dependent Myometrial Artery Vasodilator Response During Pregnancy. Hypertension. 2019 Jun;73(6):1319-1326. PubMed PMID: 31006328
• Julian CG, Moore LG. Human Genetic Adaptation to High Altitude: Evidence from the Andes. Genes (Basel). 2019 Feb 15;10(2). PubMed PMID: 30781443
• San-Millán I, Julian CG, Matarazzo C, Martinez J, Brooks GA. Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells. Front Oncol. 2019;9:1536. PubMed PMID: 32010625
• Julian CG. An Aptitude for Altitude: Are Epigenomic Processes Involved?. Front Physiol. 2019;10:1397. PubMed PMID: 31824328
• Euser AG, Hammes A, Ahrendsen JT, Neshek B, Weitzenkamp DA, Gutierrez J, Koivunen P, Julian CG, Moore LG. Gestational Diabetes Prevalence at Moderate and High Altitude. High Alt Med Biol. 2018 Dec;19(4):367-372. PubMed PMID: 30281336
• Schmidt SML, Usselman CW, Martinek E, Stickland MK, Julian CG, Chari R, Khurana R, Davidge ST, Davenport MH, Steinback CD. Activity of muscle sympathetic neurons during normotensive pregnancy. Am J Physiol Regul Integr Comp Physiol. 2018 Feb 1;314(2):R153-R160. PubMed PMID: 29046311
• Keystone Meeting, Oxford, United Kingdom, Reduced Blood Flow and Fetal Growth in High Altitude Pregnancy: Is AMPK a Potential Therapeutic Target? SL Coates, RA Lorca, CG Julian, LG Moore
• Society for Reproductive Investigation, San Diego, CA. Ex vivo peroxisome proliferator-activated receptor gamma activation opposes increased vasoconstriction in uterine artery from high altitude pregnant mice. SL Coates, RA Lorca, LG Moore, CG Julian. (*SRI Presenter's Award)
• Society for Reproductive Investigation, San Diego, CA. AMPK activation in high-altitude exposed pregnant mice is reduced in uterine artery and increased in placenta. SL Coates, ES Bales, RA Lorca, CG Julian and LG Moore.
• Society for Reproductive Investigation, San Diego, CA. High-altitude Increases the Vasodilator Effect of AMPK in Myometrial Arteries from Pregnant Women. RA Lorca, H Nsier, ES Bales, SL Coates, CG Julian and LG Moore.
• Crawford JE, Amaru R, Song J, Julian CG, Racimo F, Cheng JY, Guo X, Yao J, Ambale-Venkatesh B, Lima JA, Rotter JI, Stehlik J, Moore LG, Prchal JT, Nielsen R. Natural Selection on Genes Related to Cardiovascular Health in High-Altitude Adapted Andeans. Am J Hum Genet. 2017 Nov 2;101(5):752-767. PubMed PMID: 29100088
• Schmidt SML, Usselman CW, Martinek E, Stickland MK, Julian CG, Chari RS, Khurana R, Davidge ST, Davenport MH, Steinback CD. Activity of Muscle Sympathetic Neurons during Normotensive Pregnancy. Am J Physiol Regul Integr Comp Physiol. 2017 Oct 18;:ajpregu001212016. [Epub ahead of print] PubMed PMID: 29046311
• Julian CG. Epigenomics and human adaptation to high altitude. J Appl Physiol (1985). 2017 Nov 1;123(5):1362-1370. PubMed PMID: 28819001
• Charkoudian N, Usselman CW, Skow RJ, Staab JS, Julian CG, Stickland MK, Chari RS, Khurana R, Davidge ST, Davenport MH, Steinback CD. Muscle sympathetic nerve activity and volume-regulating factors in healthy pregnant and nonpregnant women. Am J Physiol Heart Circ Physiol. 2017 Oct 1;313(4):H782-H787. PubMed PMID: 28733450
• Tashi T, Scott Reading N, Wuren T, Zhang X, Moore LG, Hu H, Tang F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer CT, Julian CG, Shah B, Huff CD, Gordeuk VR, Prchal JT, Ge R. Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2a) polymorphism lowers hemoglobin concentration in Tibetan highlanders. J Mol Med (Berl). 2017 Jun;95(6):665-670. PubMed PMID: 28233034
• Song A, Zhang Y, Han L, Yegutkin GG, Liu H, Sun K, D'Alessandro A, Li J, Karmouty-Quintana H, Iriyama T, Weng T, Zhao S, Wang W, Wu H, Nemkov T, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Hansen KC, Zhang H, Bogdanov M, Dowhan W, Jin J, Kellems RE, Eltzschig HK, Blackburn M, Roach RC, Xia Y. Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017 Feb 7;8:14108. PubMed PMID: 28169986
• Wolfson GH, Vargas E, Browne VA, Moore LG, Julian CG. Erythropoietin and Soluble Erythropoietin Receptor: A Role for Maternal Vascular Adaptation to High-Altitude Pregnancy. J Clin Endocrinol Metab. 2017 Jan 1;102(1):242-250. PubMed PMID: 27809650
• Wolfson G, Vargas E, Browne VA, Moore LG, Julian CG. Erythropoietin and Soluble Erythropoietin Receptor: A Role for Maternal Vascular Adaptation to High Altitude Pregnancy. J Clin Endocrinol Metab. 2016 Nov 3;:jc20161767. [Epub ahead of print] PubMed PMID: 27809650
• D'Alessandro A, Nemkov T, Sun K, Liu H, Song A, Monte AA, Subudhi AW, Lovering AT, Dvorkin D, Julian CG, Kevil CG, Kolluru GK, Shiva S, Gladwin MT, Xia Y, Hansen KC, Roach RC. AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia. J Proteome Res. 2016 Oct 7;15(10):3883-3895. PubMed PMID: 27646145
• Liu H, Zhang Y, Wu H, D'Alessandro A, Yegutkin GG, Song A, Sun K, Li J, Cheng NY, Huang A, Edward Wen Y, Weng TT, Luo F, Nemkov T, Sun H, Kellems RE, Karmouty-Quintana H, Hansen KC, Zhao B, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia. Circulation. 2016 Aug 2;134(5):405-21. PubMed PMID: 27482003
• Sun K, Zhang Y, D'Alessandro A, Nemkov T, Song A, Wu H, Liu H, Adebiyi M, Huang A, Wen YE, Bogdanov MV, Vila A, O'Brien J, Kellems RE, Dowhan W, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Safo M, Hansen KC, Roach RC, Xia Y. Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia. Nat Commun. 2016 Jul 15;7:12086. PubMed PMID: 27417539
• Julian CG, Pedersen BS, Salmon CS, Yang IV, Gonzales M, Vargas E, Moore LG, Schwartz DA. Unique DNA Methylation Patterns in Offspring of Hypertensive Pregnancy. Clin Transl Sci. 2015 Dec;8(6):740-5. PubMed PMID: 26546417
• Usselman CW, Wakefield PK, Skow RJ, Stickland MK, Chari RS, Julian CG, Steinback CD, Davenport MH. Regulation of sympathetic nerve activity during the cold pressor test in normotensive pregnant and nonpregnant women. Hypertension. 2015 Oct;66(4):858-64. PubMed PMID: 26259593
• Usselman CW, Skow RJ, Matenchuk BA, Chari RS, Julian CG, Stickland MK, Davenport MH, Steinback CD. Sympathetic baroreflex gain in normotensive pregnant women. J Appl Physiol (1985). 2015 Sep 1;119(5):468-74. PubMed PMID: 26139215
• Julian CG, Gonzales M, Rodriguez A, Bellido D, Salmon CS, Ladenburger A, Reardon L, Vargas E, Moore LG. Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction. Am J Physiol Heart Circ Physiol. 2015 Aug 15;309(4):H565-73. PubMed PMID: 26092986
• Browne VA, Julian CG, Toledo-Jaldin L, Cioffi-Ragan D, Vargas E, Moore LG. Uterine artery blood flow, fetal hypoxia and fetal growth. Philos Trans R Soc Lond B Biol Sci. 2015 Mar 5;370(1663):20140068. PubMed PMID: 25602072
• Browne VA, Julian CG, Toledo-Jaldin L, Cioffi-Ragan D, Vargas E, Moore LG. Uterine artery blood flow, fetal hypoxia and fetal growth. Philos Trans R Soc Lond B Biol Sci. 2015 Mar 5;370(1663):20140068. PubMed PMID: 25602072
• Ryan BJ, Wachsmuth NB, Schmidt WF, Byrnes WC, Julian CG, Lovering AT, Subudhi AW, Roach RC. AltitudeOmics: rapid hemoglobin mass alterations with early acclimatization to and de-acclimatization from 5260 m in healthy humans. PLoS One. 2014;9(10):e108788. PubMed PMID: 25271637
• Bigham AW, Julian CG, Wilson MJ, Vargas E, Browne VA, Shriver MD, Moore LG. Maternal PRKAA1 and EDNRA genotypes are associated with birth weight, and PRKAA1 with uterine artery diameter and metabolic homeostasis at high altitude. Physiol Genomics. 2014 Sep 15;46(18):687-97. PubMed PMID: 25225183
• Hale A, Lee C, Annis S, Min PK, Pande R, Creager MA, Julian CG, Moore LG, Mitsialis SA, Hwang SJ, Kourembanas S, Chan SY. An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells. Biochim Biophys Acta. 2014 Nov;1843(11):2528-42. PubMed PMID: 24983771
• Charles SM, Julian CG, Vargas E, Moore LG. Higher estrogen levels during pregnancy in Andean than European residents of high altitude suggest differences in aromatase activity. J Clin Endocrinol Metab. 2014 Aug;99(8):2908-16. PubMed PMID: 24684460
• Subudhi AW, Bourdillon N, Bucher J, Davis C, Elliott JE, Eutermoster M, Evero O, Fan JL, Jameson-Van Houten S, Julian CG, Kark J, Kark S, Kayser B, Kern JP, Kim SE, Lathan C, Laurie SS, Lovering AT, Paterson R, Polaner DM, Ryan BJ, Spira JL, Tsao JW, Wachsmuth NB, Roach RC. AltitudeOmics: the integrative physiology of human acclimatization to hypobaric hypoxia and its retention upon reascent. PLoS One. 2014;9(3):e92191. PubMed PMID: 24658407
• Subudhi AW, Fan JL, Evero O, Bourdillon N, Kayser B, Julian CG, Lovering AT, Panerai RB, Roach RC. AltitudeOmics: cerebral autoregulation during ascent, acclimatization, and re-exposure to high altitude and its relation with acute mountain sickness. J Appl Physiol (1985). 2014 Apr 1;116(7):724-9. PubMed PMID: 24371013
• Julian CG, Yang IV, Browne VA, Vargas E, Rodriguez C, Pedersen BS, Moore LG, Schwartz DA. Inhibition of peroxisome proliferator-activated receptor ?: a potential link between chronic maternal hypoxia and impaired fetal growth. FASEB J. 2014 Mar;28(3):1268-79. PubMed PMID: 24307415
• Julian CG, Subudhi AW, Hill RC, Wilson MJ, Dimmen AC, Hansen KC, Roach RC. Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans. J Appl Physiol (1985). 2014 Apr 1;116(7):937-44. PubMed PMID: 24265281
• Subudhi AW, Fan JL, Evero O, Bourdillon N, Kayser B, Julian CG, Lovering AT, Roach RC. AltitudeOmics: effect of ascent and acclimatization to 5260 m on regional cerebral oxygen delivery. Exp Physiol. 2014 May 1;99(5):772-81. PubMed PMID: 24243839
• Subudhi AW, Fan JL, Evero O, Bourdillon N, Kayser B, Julian CG, Lovering AT, Panerai RB, Roach RC. AltitudeOmics: Cerebral autoregulation during ascent, acclimatization, and re-exposure to high altitude and its relation with acute mountain sickness. J Appl Physiol (1985). 2013 Dec 26. [Epub ahead of print] PubMed PMID: 24371013
• Julian CG, Yang IV, Browne VA, Vargas E, Rodriguez C, Pedersen BS, Moore LG, Schwartz DA. Inhibition of peroxisome proliferator-activated receptor ?: a potential link between chronic maternal hypoxia and impaired fetal growth. FASEB J. 2013 Dec 4. [Epub ahead of print] PubMed PMID: 24307415
• Julian CG, Subudhi AW, Hill RC, Wilson MJ, Dimmen AC, Hansen KC, Roach RC. Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness and in humans. J Appl Physiol (1985). 2013 Nov 21. [Epub ahead of print] PubMed PMID: 24265281
• Subudhi AW, Fan JL, Evero O, Bourdillon N, Kayser B, Julian CG, Lovering AT, Roach RC. AltitudeOmics: Effect of ascent and acclimatization to 5260 m on regional cerebral oxygen delivery. Exp Physiol. 2013 Nov 15. [Epub ahead of print] PubMed PMID: 24243839
• Soria R, Julian CG, Vargas E, Moore LG, Giussani DA. Graduated effects of high-altitude hypoxia and highland ancestry on birth size. Pediatr Res. 2013 Dec;74(6):633-8. PubMed PMID: 23999073
• Schwartz J, Cioffi-Ragan D, Wilson MJ, Julian CG, Beatty B, Moore LG, Galan HL. Little effect of gestation at 3,100 m on fetal fat accretion or the fetal circulation. Am J Hum Biol. 2013 Jul-Aug;25(4):544-9. PubMed PMID: 23754523
• Julian CG, Vargas E, Gonzales M, Dávila RD, Ladenburger A, Reardon L, Schoo C, Powers RW, Lee-Chiong T, Moore LG. Sleep-disordered breathing and oxidative stress in preclinical chronic mountain sickness (excessive erythrocytosis). Respir Physiol Neurobiol. 2013 Apr 1;186(2):188-96. PubMed PMID: 23380170
• Bigham AW, Wilson MJ, Julian CG, Kiyamu M, Vargas E, Leon-Velarde F, Rivera-Chira M, Rodriquez C, Browne VA, Parra E, Brutsaert TD, Moore LG, Shriver MD. Andean and Tibetan patterns of adaptation to high altitude. Am J Hum Biol. 2013 Mar-Apr;25(2):190-7. PubMed PMID: 23348729
• Dávila RD, Julian CG, Browne VA, Toledo-Jaldin L, Wilson MJ, Rodriguez A, Vargas E, Moore LG. Role of cytokines in altitude-associated preeclampsia. Pregnancy Hypertens. 2012 Jan;2(1):65-70. PubMed PMID: 22247821
• Julian CG, Vargas E, Browne VA, Wilson MJ, Bigham AW, Rodriguez C, McCord JM, Moore LG. Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA. J Matern Fetal Neonatal Med. 2012 Aug;25(8):1233-40. PubMed PMID: 22082238
• Subudhi AW, Dimmen AC, Julian CG, Wilson MJ, Panerai RB, Roach RC. Effects of acetazolamide and dexamethasone on cerebral hemodynamics in hypoxia. J Appl Physiol (1985). 2011 May;110(5):1219-25. PubMed PMID: 21393464
• Browne VA, Toledo-Jaldin L, Davila RD, Lopez LP, Yamashiro H, Cioffi-Ragan D, Julian CG, Wilson MJ, Bigham AW, Shriver MD, Honigman B, Vargas E, Roach R, Moore LG. High-end arteriolar resistance limits uterine artery blood flow and restricts fetal growth in preeclampsia and gestational hypertension at high altitude. Am J Physiol Regul Integr Comp Physiol. 2011 May;300(5):R1221-9. PubMed PMID: 21325643
• Wilson MJ, Julian CG, Roach RC. Genomic analysis of high altitude adaptation: innovations and implications. Curr Sports Med Rep. 2011 Mar-Apr;10(2):59-61. PubMed PMID: 21603073
• Julian CG. High altitude during pregnancy. Clin Chest Med. 2011 Mar;32(1):21-31. PubMed PMID: 21277446
• Julian CG, Hageman JL, Wilson MJ, Vargas E, Moore LG. Lowland origin women raised at high altitude are not protected against lower uteroplacental O2 delivery during pregnancy or reduced birth weight. Am J Hum Biol. 2011 Jul-Aug;23(4):509-16. PubMed PMID: 21538651
• Dávila RD, Julian CG, Wilson MJ, Browne VA, Rodriguez C, Bigham AW, Shriver MD, Vargas E, Moore LG. Do cytokines contribute to the Andean-associated protection from reduced fetal growth at high altitude?. Reprod Sci. 2011 Jan;18(1):79-87. PubMed PMID: 20841404
• Moore LG, Charles SM, Julian CG. Humans at high altitude: hypoxia and fetal growth. Respir Physiol Neurobiol. 2011 Aug 31;178(1):181-90. PubMed PMID: 21536153
• Julian CG, Subudhi AW, Wilson MJ, Dimmen AC, Pecha T, Roach RC. Acute mountain sickness, inflammation, and permeability: new insights from a blood biomarker study. J Appl Physiol (1985). 2011 Aug;111(2):392-9. PubMed PMID: 21636566
• Julian, C. High altitude and pregnancy. Invited review for Clinics in Chest Medicine Pulmonary Disease and Pregnancy, Guest Editor: G. Bourjeily; March 2011 (Vol 32, Issue 1).
• Julian CG, Hageman J, Wilson MJ, Vargas E, Moore LG. No effect of lifelong high-altitude residence on raising uteroplacental O2 delivery during pregnancy or protecting against lower birth weight; Am J Hum Biol, 2011, Jul-Aug;23(4):509-16.
• Davila RD*, Julian CG*, Browne VA, Toledo-Jaldin L, Wilson MJ, Rodriguez A,Vargas E, Moore LG. Role of cytokines in altitude-associated preeclampsia. Pregnancy Hypertens. 2012 Jan;2(1):65-70. PubMed PMID: 22247821; PubMed Central PMCID: PMC3257024. *Co-first authors
• Julian CG, Vargas E, Browne VA, Wilson MJ, Bigham AW, Rodriguez C, McCord JM, Moore LG. Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA. J Matern Fetal Neonatal Med. 2011 Nov 30. PubMed PMID: 22082238.
• Julian CG, Subudhi AW, Wilson MJ, Dimmen AC, Pecha T, Roach RC. Acute mountain sickness, inflammation, and permeability: new insights from a blood biomarker study. J Appl Physiol. 2011 Aug;111(2):392-9. Epub 2011 Jun 2. PubMed PMID: 21636566; PubMed Central PMCID: PMC3154693.
• Moore LG, Charles S, Julian CG. Humans at high altitude: hypoxia and fetal growth [special Issue on “Energetics and oxygen transport mechanisms during embryonic development”]. Respir Physiol Neurobiol. 2011 Aug 31;178 (1):181-90.
• Dávila RD, Julian CG, Wilson MJ, Browne VA, Rodriguez C, Bigham AW, Shriver MD, Vargas E, Moore LG. Do anti-angiogenic or angiogenic factors contribute to the protection of birth weight at high altitude afforded by Andean ancestry?. Reprod Sci. 2010 Sep;17(9):861-70. PubMed PMID: 20601535
• Julian CG, Wilson MJ, Moore LG. Evolutionary adaptation to high altitude: a view from in utero. Am J Hum Biol. 2009 Sep-Oct;21(5):614-22. PubMed PMID: 19367578
• Julian CG, Wilson MJ, Lopez M, Yamashiro H, Tellez W, Rodriguez A, Bigham AW, Shriver MD, Rodriguez C, Vargas E, Moore LG. Augmented uterine artery blood flow and oxygen delivery protect Andeans from altitude-associated reductions in fetal growth. Am J Physiol Regul Integr Comp Physiol. 2009 May;296(5):R1564-75. PubMed PMID: 19244584
• Bigham AW, Mao X, Mei R, Brutsaert T, Wilson MJ, Julian CG, Parra EJ, Akey JM, Moore LG, Shriver MD. Identifying positive selection candidate loci for high-altitude adaptation in Andean populations. Hum Genomics. 2009 Dec;4(2):79-90. PubMed PMID: 20038496
• Julian CG, Galan HL, Wilson MJ, Desilva W, Cioffi-Ragan D, Schwartz J, Moore LG. Lower uterine artery blood flow and higher endothelin relative to nitric oxide metabolite levels are associated with reductions in birth weight at high altitude. Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R906-15. PubMed PMID: 18579652
• Vargas M, Vargas E, Julian CG, Armaza JF, Rodriguez A, Tellez W, Niermeyer S, Wilson M, Parra E, Shriver M, Moore LG. Determinants of blood oxygenation during pregnancy in Andean and European residents of high altitude. Am J Physiol Regul Integr Comp Physiol. 2007 Sep;293(3):R1303-12. PubMed PMID: 17609312
• Julian CG, Vargas E, Armaza JF, Wilson MJ, Niermeyer S, Moore LG. High-altitude ancestry protects against hypoxia-associated reductions in fetal growth. Arch Dis Child Fetal Neonatal Ed. 2007 Sep;92(5):F372-7. PubMed PMID: 17329275
• Julian CG, Gore CJ, Wilber RL, Daniels JT, Fredericson M, Stray-Gundersen J, Hahn AG, Parisotto R, Levine BD. Intermittent normobaric hypoxia does not alter performance or erythropoietic markers in highly trained distance runners. J Appl Physiol (1985). 2004 May;96(5):1800-7. PubMed PMID: 14672967
• Moore LG and Julian CG. Human Genetic Adaptation to High Altitude: Evidence from the Andes, Genes [accepted on 02/10/19 for Special Issue: Genetic Epidemiology of Complex Diseases in Latin America]