Kristen Nordenholz, MD
Professor, Emergency Medicine
Medical School:
Department: Emergency Medicine
- MD, University of Rochester School of Medicine and Dentistry (1992)
- MSc, University of Colorado Health Sciences Center (2012)
- BS, Cornell University (NY) (1988)
- Johns Hopkins University School of Medicine Program (1993)
- Johns Hopkins University School of Medicine Program, Chief Resident, Emergency Medicine (1995)
Department: Emergency Medicine
Publications
- Thoppil JJ, Stewart LK, Pung L, Nordenholz KE, Camargo CA, Courtney DM, Kline JA. Increased Body Mass Index and Metabolic Syndrome Are Associated with Poor Outcomes in SARS-CoV-2-Positive Emergency Department Patients. J Obes Metab Syndr. 2022 Sep 30;31(3):245-253. PubMed PMID: 35918837
- Lu DW, Lee J, Alvarez A, Sakamoto JT, Bird SB, Sundaram V, Lall MD, Nordenholz KE, Manfredi RA, Blomkalns AL. Drivers of professional fulfillment and burnout among emergency medicine faculty: A national wellness survey by the Society for Academic Emergency Medicine. Acad Emerg Med. 2022 Aug;29(8):987-998. PubMed PMID: 35304931
- Thoppil JJ, Courtney DM, McDonald S, Kabrhel C, Nordenholz KE, Camargo CA Jr, Kline JA. SARS-CoV-2 Positivity in Ambulatory Symptomatic Patients Is Not Associated With Increased Venous or Arterial Thrombotic Events in the Subsequent 30 Days. J Emerg Med. 2022 Jun;62(6):716-724. PubMed PMID: 35177286
- Thomas SA, Puskarich M, Pulia MS, Meltzer AC, Camargo CA, Courtney DM, Nordenholz KE, Kline JA, Kabrhel C. Association Between Baseline Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Death Among Patients Tested for COVID-19. J Clin Pharmacol. 2022 Jun;62(6):777-782. PubMed PMID: 34921684
- Glober N, Stewart L, Seo J, Kabrhel C, Nordenholz K, Camargo C, Kline J. Incidence and characteristics of arterial thromboemboli in patients with COVID-19. Thromb J. 2021 Dec 20;19(1):104. PubMed PMID: 34930306
- Thomas SA, Puskarich M, Pulia MS, Meltzer AC, Camargo CA, Courtney DM, Nordenholz KE, Kline JA, Kabrhel C. Association between baseline use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers and death among patients tested for COVID-19. J Clin Pharmacol. 2021 Dec 18. [Epub ahead of print] PubMed PMID: 34921684
- Bennett CL, Ogele E, Pettit NR, Bischof JJ, Meng T, Govindarajan P, Camargo CA Jr, Nordenholz K, Kline JA. Multicenter Study of Outcomes Among Persons With HIV Who Presented to US Emergency Departments With Suspected SARS-CoV-2. J Acquir Immune Defic Syndr. 2021 Dec 1;88(4):406-413. PubMed PMID: 34483295
- Kline JA, Adler DH, Alanis N, Bledsoe JR, Courtney DM, d'Etienne JP, Diercks DB, Garrett JS, Jones AE, Mackenzie DC, Madsen T, Matuskowitz AJ, Mumma BE, Nordenholz KE, Pagenhardt J, Runyon MS, Stubblefield WB, Willoughby CB. Monotherapy Anticoagulation to Expedite Home Treatment of Patients Diagnosed With Venous Thromboembolism in the Emergency Department: A Pragmatic Effectiveness Trial. Circ Cardiovasc Qual Outcomes. 2021 Jul;14(7):e007600. PubMed PMID: 34148351
- Kline JA, Camargo CA Jr, Courtney DM, Kabrhel C, Nordenholz KE, Aufderheide T, Baugh JJ, Beiser DG, Bennett CL, Bledsoe J, Castillo E, Chisolm-Straker M, Goldberg EM, House H, House S, Jang T, Lim SC, Madsen TE, McCarthy DM, Meltzer A, Moore S, Newgard C, Pagenhardt J, Pettit KL, Pulia MS, Puskarich MA, Southerland LT, Sparks S, Turner-Lawrence D, Vrablik M, Wang A, Weekes AJ, Westafer L, Wilburn J. Clinical prediction rule for SARS-CoV-2 infection from 116 U.S. emergency departments 2-22-2021. PLoS One. 2021;16(3):e0248438. PubMed PMID: 33690722
- Glober N, Stewart L, Seo J, Kabrhel C, Nordenholz K, Camargo C, Kline J. Incidence and characteristics of arterial thromboemboli in patients with COVID-19. Thromb J. 2021 Dec 20;19(1):104. PubMed PMID: 34930306
- Bennett CL, Ogele E, Pettit NR, Bischof JJ, Meng T, Govindarajan P, Camargo CA Jr, Nordenholz K, Kline JA. Multicenter Study of Outcomes Among Persons With HIV Who Presented to US Emergency Departments With Suspected SARS-CoV-2. J Acquir Immune Defic Syndr. 2021 Dec 1;88(4):406-413. PubMed PMID: 34483295
- Kline JA, Adler DH, Alanis N, Bledsoe JR, Courtney DM, d'Etienne JP, Diercks DB, Garrett JS, Jones AE, Mackenzie DC, Madsen T, Matuskowitz AJ, Mumma BE, Nordenholz KE, Pagenhardt J, Runyon MS, Stubblefield WB, Willoughby CB. Monotherapy Anticoagulation to Expedite Home Treatment of Patients Diagnosed With Venous Thromboembolism in the Emergency Department: A Pragmatic Effectiveness Trial. Circ Cardiovasc Qual Outcomes. 2021 Jul;14(7):e007600. PubMed PMID: 34148351
- Kline JA, Camargo CA Jr, Courtney DM, Kabrhel C, Nordenholz KE, Aufderheide T, Baugh JJ, Beiser DG, Bennett CL, Bledsoe J, Castillo E, Chisolm-Straker M, Goldberg EM, House H, House S, Jang T, Lim SC, Madsen TE, McCarthy DM, Meltzer A, Moore S, Newgard C, Pagenhardt J, Pettit KL, Pulia MS, Puskarich MA, Southerland LT, Sparks S, Turner-Lawrence D, Vrablik M, Wang A, Weekes AJ, Westafer L, Wilburn J. Clinical prediction rule for SARS-CoV-2 infection from 116 U.S. emergency departments 2-22-2021. PLoS One. 2021;16(3):e0248438. PubMed PMID: 33690722
- Kline JA, Pettit KL, Kabrhel C, Courtney DM, Nordenholz KE, Camargo CA. Multicenter registry of United States emergency department patients tested for SARS-CoV-2. J Am Coll Emerg Physicians Open. 2020 Dec;1(6):1341-1348. PubMed PMID: 33392542
- Kline J, Adler D, Alanis N, Bledsoe J, Courtney D, D'Etienne J, B Diercks D, Garrett J, Jones AE, MacKenzie D, Madsen T, Matuskowitz A, Mumma B, Nordenholz K, Pagenhardt J, Runyon M, Stubblefield W, Willoughby C. Study protocol for a multicentre implementation trial of monotherapy anticoagulation to expedite home treatment of patients diagnosed with venous thromboembolism in the emergency department. BMJ Open. 2020 Oct 1;10(10):e038078. PubMed PMID: 33004396
- Nordenholz, K. E., Alvarez, A., Lall, M. D., Stehman, C., Bitter, C. C., Hirsh, E. L., Manfredi, R., Sikora, R. D., Lu, D. W., Sanchez, L. D., Wong, M. L., Bird, S., & Blomkalns, A. L. (2020). Optimizing Wellness in Academic Emergency Medicine. Journal of Wellness, 2(2), article 8, 1-12. doi: 10.18297/jwellness/vol2/iss2/8
- Stewart LK, Nordenholz KE, Courtney M, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Kline JA. Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo. Blood Coagul Fibrinolysis. 2017 Sep 27. [Epub ahead of print] PubMed PMID: 28957940
- Rigual D, Rove M, Robison Z, Nordenholz K, Cumbler E, Dodd G, Borgstede J. Emergency Department CT Expediency: A Time Reduction by Redesign. J Am Coll Radiol. 2016 Feb;13(2):178-81. PubMed PMID: 26507822
- Kim DJ, Byyny RL, Rice CA, Faragher JP, Nordenholz KE, Haukoos JS, Liao MM, Kendall JL. Test Characteristics of Emergency Physician-Performed Limited Compression Ultrasound for Lower-Extremity Deep Vein Thrombosis. J Emerg Med. 2016 Dec;51(6):684-690. PubMed PMID: 27637139
- Rigual D, Rove M, Robison Z, Nordenholz K, Cumbler E, Dodd G, Borgstede J. Emergency Department CT Expediency: A Time Reduction by Redesign. J Am Coll Radiol. 2016 Feb;13(2):178-81. PubMed PMID: 26507822
- Kim DJ, Byyny RL, Rice CA, Faragher JP, Nordenholz KE, Haukoos JS, Liao MM, Kendall JL. Test Characteristics of Emergency Physician-Performed Limited Compression Ultrasound for Lower-Extremity Deep Vein Thrombosis. J Emerg Med. 2016 Dec;51(6):684-690. PubMed PMID: 27637139
- Rigual D, Rove M, Robison Z, Nordenholz K, Cumbler E, Dodd G, Borgstede J. Emergency Department CT Expediency: A Time Reduction by Redesign. J Am Coll Radiol. 2016 Feb;13(2):178-81. PubMed PMID: 26507822
- Russell FM, Moore CL, Courtney DM, Kabrhel C, Smithline HA, Nordenholz KE, Richman PB, O'Neil BJ, Plewa MC, Beam DM, Mastouri R, Kline JA. Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath. Am J Emerg Med. 2015 Apr;33(4):542-7. PubMed PMID: 25769797
- Stewart LK, Peitz GW, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Kline JA. Contribution of fibrinolysis to the physical component summary of the SF-36 after acute submassive pulmonary embolism. J Thromb Thrombolysis. 2015 Aug;40(2):161-6. PubMed PMID: 25433511
- Russell FM, Moore CL, Courtney DM, Kabrhel C, Smithline HA, Nordenholz KE, Richman PB, O'Neil BJ, Plewa MC, Beam DM, Mastouri R, Kline JA. Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath. Am J Emerg Med. 2015 Apr;33(4):542-7. PubMed PMID: 25769797
- Stewart LK, Peitz GW, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Kline JA. Contribution of fibrinolysis to the physical component summary of the SF-36 after acute submassive pulmonary embolism. J Thromb Thrombolysis. 2015 Aug;40(2):161-6. PubMed PMID: 25433511
- Kline JA, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Hernandez J. Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at three months (TOPCOAT): Multicenter double-blind, placebo-controlled randomized trial. J Thromb Haemost. 2014 Jan 31. [Epub ahead of print] PubMed PMID: 24484241
- Stewart LK, Peitz GW, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Kline JA. Contribution of fibrinolysis to the physical component summary of the SF-36 after acute submassive pulmonary embolism. J Thromb Thrombolysis. 2014 Nov 30. [Epub ahead of print] PubMed PMID: 25433511
- Misky GJ, Carlson T, Thompson E, Trujillo T, Nordenholz K. Implementation of an acute venous thromboembolism clinical pathway reduces healthcare utilization and mitigates health disparities. J Hosp Med. 2014 Jul;9(7):430-5. PubMed PMID: 24639293
- Miller MP, Trujillo TC, Nordenholz KE. Practical considerations in emergency management of bleeding in the setting of target-specific oral anticoagulants. Am J Emerg Med. 2014 Apr;32(4):375-82. PubMed PMID: 24512886
- Kline JA, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Hernandez J. Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at 3 months: multicenter double-blind, placebo-controlled randomized trial. J Thromb Haemost. 2014 Apr;12(4):459-68. PubMed PMID: 24484241
- Miller MP, Trujillo TC, Nordenholz KE. Practical considerations in emergency management of bleeding in the setting of target-specific oral anticoagulants. Am J Emerg Med. 2013 Dec 7. [Epub ahead of print] PubMed PMID: 24512886
- Kline JA, Hernandez J, Hogg MM, Jones AE, Courtney DM, Kabrhel C, Nordenholz KE, Diercks DB, Rondina MT, Klinger JR. Rationale and methodology for a multicentre randomised trial of fibrinolysis for pulmonary embolism that includes quality of life outcomes. Emerg Med Australas. 2013 Dec;25(6):515-26. PubMed PMID: 24224521
Practice Locations
UCHealth Emergency Care - Anschutz Medical Campus (Hospital-based)
12505 E. 16th Ave
Aurora, CO 80045
720-848-9111
Hospital Affiliation
12505 E. 16th Ave
Aurora, CO 80045
720-848-9111
Hospital Affiliation
- University of Colorado Hospital
Specialty Information
Specialties
- Emergency Medicine, Board Certification
- IHQSE, Certificate (2014)
- Emergency Care
General Information
Medical Schools:
- MD, University of Rochester School of Medicine and Dentistry (1992)
Graduate Schools:
- MSc, University of Colorado Health Sciences Center (2012)
Undergraduate Schools:
- BS, Cornell University (NY) (1988)
Internships:
- Johns Hopkins University School of Medicine Program (1993)
Residency Programs:
- Johns Hopkins University School of Medicine Program, Chief Resident, Emergency Medicine (1995)
Department: Emergency Medicine