Michael McMurray, PhD

Publications

• Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation. Garcia G 3rd, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E. J Cell Biol. 2011 Dec 12;195(6):993-1004. Epub 2011 Dec 5. PMID: 22144691
• Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae. Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, García G 3rd, Peters P, Thorner J, Nogales E. Mol Biol Cell. 2012 Feb;23(3):423-32. Epub 2011 Dec 7. PMID: 22160597
• de Val N, McMurray MA, Lam LH, Hsiung CC, Bertin A, Nogales E, Thorner J. Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins. Proteins. 2013 Nov;81(11):1964-79. PubMed PMID: 23775754
• Heasley LR, Garcia G 3rd, McMurray MA. Off-target effects of the septin drug forchlorfenuron on nonplant eukaryotes. Eukaryot Cell. 2014 Nov;13(11):1411-20. PubMed PMID: 25217460
• Weems AD, Johnson CR, Argueso JL, McMurray MA. Higher-order septin assembly is driven by GTP-promoted conformational changes: evidence from unbiased mutational analysis in Saccharomyces cerevisiae. Genetics. 2014 Mar;196(3):711-27. PubMed PMID: 24398420
• McMurray M. Lean forward: Genetic analysis of temperature-sensitive mutants unfolds the secrets of oligomeric protein complex assembly. Bioessays. 2014 Sep;36(9):836-46. PubMed PMID: 25048147
• Heasley LR, McMurray MA. Roles of septins in prospore membrane morphogenesis and spore wall assembly in Saccharomyces cerevisiae. Mol Biol Cell. 2016 Feb 1;27(3):442-50. PubMed PMID: 26680739
• Johnson CR, Weems AD, Brewer JM, Thorner J, McMurray MA. Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast. Mol Biol Cell. 2015 Apr 1;26(7):1323-44. PubMed PMID: 25673805
• McMurray MA. Coupling de novo protein folding with subunit exchange into pre-formed oligomeric protein complexes: the 'heritable template' hypothesis. Biomol Concepts. 2016 Dec 1;7(5-6):271-281. PubMed PMID: 27875316
• Heasley LR, McMurray MA. Small molecule perturbations of septins. Methods Cell Biol. 2016;136:311-9. PubMed PMID: 27473917
• McMurray MA. Assays for genetic dissection of septin filament assembly in yeast, from de novo folding through polymerization. Methods Cell Biol. 2016;136:99-116. PubMed PMID: 27473905
• Schaefer RM, Heasley LR, Odde DJ, McMurray MA. Kinetic partitioning during de novo septin filament assembly creates a critical G1 "window of opportunity" for mutant septin function. Cell Cycle. 2016 Sep 16;15(18):2441-53. PubMed PMID: 27398993
• Garcia G 3rd, Finnigan GC, Heasley LR, Sterling SM, Aggarwal A, Pearson CG, Nogales E, McMurray MA, Thorner J. Assembly, molecular organization, and membrane-binding properties of development-specific septins. J Cell Biol. 2016 Feb 29;212(5):515-29. PubMed PMID: 26929450
• Heasley LR, McMurray MA. Roles of septins in prospore membrane morphogenesis and spore wall assembly in Saccharomyces cerevisiae. Mol Biol Cell. 2016 Feb 1;27(3):442-50. PubMed PMID: 26680739
• Weems A, McMurray M. The step-wise pathway of septin hetero-octamer assembly in budding yeast. Elife. 2017 May 25;6. PubMed PMID: 28541184
• Barve G, Sridhar S, Aher A, Sahani MH, Chinchwadkar S, Singh S, K N L, McMurray MA, Manjithaya R. Septins are involved at the early stages of macroautophagy in S. cerevisiae . J Cell Sci. 2018 Feb 22;131(4). PubMed PMID: 29361537
• McMurray MA, Thorner J. Turning it inside out: The organization of human septin heterooligomers. Cytoskeleton (Hoboken). 2019 Sep;76(9-10):449-456. PubMed PMID: 31614074
• McMurray MA. The long and short of membrane curvature sensing by septins. J Cell Biol. 2019 Apr 1;218(4):1083-1085. PubMed PMID: 30890557
• Johnson CR, Steingesser MG, Weems AD, Khan A, Gladfelter A, Bertin A, McMurray MA. Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast. Elife. 2020 Jan 28;9. PubMed PMID: 31990274
• Heasley LR, Singer E, Cooperman BJ, McMurray MA. Saccharomyces spores are born prepolarized to outgrow away from spore-spore connections and penetrate the ascus wall. Yeast. 2020 Nov 25. [Epub ahead of print] PubMed PMID: 33238051
• Spiliotis ET, McMurray MA. Masters of asymmetry - lessons and perspectives from 50 years of septins. Mol Biol Cell. 2020 Oct 1;31(21):2289-2297. PubMed PMID: 32991244
• Hassell DS, Steingesser MG, Denney AS, Johnson CR, McMurray MA. Chemical rescue of mutant proteins in living Saccharomyces cerevisiae cells by naturally occurring small molecules. G3 (Bethesda). 2021 Sep 6;11(9). PubMed PMID: 34544143
• Denney AS, Weems AD, McMurray MA. Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast. G3 (Bethesda). 2021 Sep 6;11(9). PubMed PMID: 34544131
• Yeager R, Bushkin GG, Singer E, Fu R, Cooperman B, McMurray M. Post-Transcriptional Control of Mating-Type Gene Expression during Gametogenesis in Saccharomyces cerevisiae . Biomolecules. 2021 Aug 17;11(8). PubMed PMID: 34439889
• Heasley LR, Singer E, Cooperman BJ, McMurray MA. Saccharomyces spores are born prepolarized to outgrow away from spore-spore connections and penetrate the ascus wall. Yeast. 2021 Jan;38(1):90-101. PubMed PMID: 33238051
• Baillet A, McMurray MA, Oakes PW. Meeting report - the ever-fascinating world of septins. J Cell Sci. 2021 Dec 15;134(24). PubMed PMID: 34910818
• Galvin J, Curran E, Arteaga F, Goossens A, Aubuchon-Endsley N, McMurray MA, Moore J, Hansen KC, Chial HJ, Potter H, Brodsky JL, Coughlan CM. Proteasome activity modulates amyloid toxicity. FEMS Yeast Res. 2022 Mar 9;22(1). PubMed PMID: 35150241
• Hassell D, Denney A, Singer E, Benson A, Roth A, Ceglowski J, Steingesser M, McMurray M. Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins. Mol Biol Cell. 2022 Oct 1;33(12):ar111. PubMed PMID: 35947497
• Benson A, McMurray M. Simultaneous co-overexpression of Saccharomyces cerevisiae septins Cdc3 and Cdc10 drives pervasive, phospholipid-, and tag-dependent plasma membrane localization. Cytoskeleton (Hoboken). 2023 Jul-Aug;80(7-8):199-214. PubMed PMID: 37098755
• Hussain A, Nguyen VT, Reigan P, McMurray M. Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface. Front Cell Dev Biol. 2023;11:1296657. PubMed PMID: 38125875