Jordan Jacobelli, PhD
Associate Professor, Immunology and Microbiology


  • Waldman MM, Rahkola JT, Sigler AL, Chung JW, Willett BAS, Kedl RM, Friedman RS, Jacobelli J. Ena/VASP Protein-Mediated Actin Polymerization Contributes to Naïve CD8( ) T Cell Activation and Expansion by Promoting T Cell-APC Interactions In Vivo . Front Immunol. 2022;13:856977. PubMed PMID: 35757762
  • Kremer KN, Buser A, Thumkeo D, Narumiya S, Jacobelli J, Pelanda R, Torres RM. LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2118816119. PubMed PMID: 35394866
  • Jacobelli J, Buser AE, Heiden DL, Friedman RS. Autoimmunity in motion: Mechanisms of immune regulation and destruction revealed by in vivo imaging. Immunol Rev. 2022 Mar;306(1):181-199. PubMed PMID: 34825390
  • Thompson SB, Waldman MM, Jacobelli J. Polymerization power: effectors of actin polymerization as regulators of T lymphocyte migration through complex environments. FEBS J. 2022 Oct;289(20):6154-6171. PubMed PMID: 34273243
  • Lindsay RS, Whitesell JC, Dew KE, Rodriguez E, Sandor AM, Tracy D, Yannacone SF, Basta BN, Jacobelli J, Friedman RS. MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites. J Exp Med. 2021 Oct 4;218(10). PubMed PMID: 34415994
  • Thompson SB, Waldman MM, Jacobelli J. Polymerization power: effectors of actin polymerization as regulators of T lymphocyte migration through complex environments. FEBS J. 2021 Jul 17. [Epub ahead of print] PubMed PMID: 34273243
  • Jha V, Nicholson LK, Gardner EM, Rahkola JT, Pratap H, Scott J, Borgeson M, Jacobelli J, Janoff EN. Impact of HIV-1 Infection and Antigen Class on T Follicular Helper Cell Responses to Pneumococcal Polysaccharide-Protein Conjugate Vaccine-13. J Immunol. 2021 May 15;206(10):2402-2411. PubMed PMID: 33931485
  • Thompson SB, Sandor AM, Lui V, Chung JW, Waldman MM, Long RA, Estin ML, Matsuda JL, Friedman RS, Jacobelli J. Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity. Elife. 2020 Jun 8;9. PubMed PMID: 32510333
  • Sandor AM, Jacobelli J, Friedman RS. Immune cell trafficking to the islets during type 1 diabetes. Clin Exp Immunol. 2019 Jul 25. [Epub ahead of print] PubMed PMID: 31343073
  • Sandor AM, Lindsay RS, Dyjack N, Whitesell JC, Rios C, Bradley BJ, Haskins K, Serreze DV, Geurts AM, Chen YG, Seibold MA, Jacobelli J, Friedman RS. CD11c( ) Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes. Front Immunol. 2019;10:99. PubMed PMID: 30766536
  • Krummel MF, Friedman RS, Jacobelli J. Modes and mechanisms of T cell motility: roles for confinement and Myosin-IIA. Curr Opin Cell Biol. 2014 Jun 3;30C:9-16. [Epub ahead of print] PubMed PMID: 24905977
  • Friedman RS, Lindsay RS, Lilly JK, Nguyen V, Sorensen CM, Jacobelli J, Krummel MF. An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9223-8. PubMed PMID: 24927530
  • Jacobelli J, Lindsay RS, Friedman RS. Peripheral tolerance and autoimmunity: lessons from in vivo imaging. Immunol Res. 2013 Mar;55(1-3):146-54. PubMed PMID: 22956468
  • Huang Y, Aydintug MK, Loomis J, Macleod MK, McKee AS, Kirchenbaum G, Jakubzick CV, Kedl RM, Sun D, Jacobelli J, O'Brien RL, Born WK. Antigen-specific regulation of IgE antibodies by non-antigen-specific ?d T cells. J Immunol. 2013 Feb 1;190(3):913-21. PubMed PMID: 23275606
  • Gérard A, Beemiller P, Friedman RS, Jacobelli J, Krummel MF. Evolving immune circuits are generated by flexible, motile, and sequential immunological synapses. Immunol Rev. 2013 Jan;251(1):80-96. PubMed PMID: 23278742
  • McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):E1122-31. PubMed PMID: 23447566
  • Jacobelli J, Estin Matthews M, Chen S, Krummel MF. Activated T cell trans-endothelial migration relies on myosin-IIA contractility for squeezing the cell nucleus through endothelial cell barriers. PLoS One. 2013;8(9):e75151. PubMed PMID: 24069389
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Practice Locations

UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045

General Information

Department: Immunology and Microbiology
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CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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