Rachel Friedman, PhD
Associate Professor, Immunology and Microbiology

Publications

  • Waldman MM, Rahkola JT, Sigler AL, Chung JW, Willett BAS, Kedl RM, Friedman RS, Jacobelli J. Ena/VASP Protein-Mediated Actin Polymerization Contributes to Naïve CD8( ) T Cell Activation and Expansion by Promoting T Cell-APC Interactions In Vivo. Front Immunol. 2022;13:856977. PubMed PMID: 35757762
  • Jacobelli J, Buser AE, Heiden DL, Friedman RS. Autoimmunity in motion: Mechanisms of immune regulation and destruction revealed by in vivo imaging. Immunol Rev. 2022 Mar;306(1):181-199. PubMed PMID: 34825390
  • Whitesell JC, Lindsay RS, Olivas-Corral JG, Yannacone SF, Schoenbach MH, Lucas ED, Friedman RS. Islet Lymphocytes Maintain a Stable Regulatory Phenotype Under Homeostatic Conditions and Metabolic Stress. Front Immunol. 2022;13:814203. PubMed PMID: 35145521
  • Lindsay RS, Whitesell JC, Dew KE, Rodriguez E, Sandor AM, Tracy D, Yannacone SF, Basta BN, Jacobelli J, Friedman RS. MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites. J Exp Med. 2021 Oct 4;218(10). PubMed PMID: 34415994
  • Summers ME, Richmond BW, Menon S, Sheridan RM, Kropski JA, Majka SA, Taketo MM, Bastarache JA, West JD, De Langhe S, Geraghty P, Klemm DJ, Chu HW, Friedman RS, Tao YK, Foronjy RF, Majka SM. Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling. FASEB J. 2020 Jun 13. [Epub ahead of print] PubMed PMID: 32533805
  • Thompson SB, Sandor AM, Lui V, Chung JW, Waldman MM, Long RA, Estin ML, Matsuda JL, Friedman RS, Jacobelli J. Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity. Elife. 2020 Jun 8;9. PubMed PMID: 32510333
  • Sandor AM, Jacobelli J, Friedman RS. Immune cell trafficking to the islets during type 1 diabetes. Clin Exp Immunol. 2019 Dec;198(3):314-325. PubMed PMID: 31343073
  • Sandor AM, Lindsay RS, Dyjack N, Whitesell JC, Rios C, Bradley BJ, Haskins K, Serreze DV, Geurts AM, Chen YG, Seibold MA, Jacobelli J, Friedman RS. CD11c( ) Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes. Front Immunol. 2019;10:99. PubMed PMID: 30766536
  • Friedman RS, Lindsay RS, Lilly JK, Nguyen V, Sorensen CM, Jacobelli J, Krummel MF. An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9223-8. PubMed PMID: 24927530
  • Krummel MF, Friedman RS, Jacobelli J. Modes and mechanisms of T cell motility: roles for confinement and Myosin-IIA. Curr Opin Cell Biol. 2014 Jun 3;30C:9-16. [Epub ahead of print] PubMed PMID: 24905977
  • McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):E1122-31. PubMed PMID: 23447566
  • Gérard A, Beemiller P, Friedman RS, Jacobelli J, Krummel MF. Evolving immune circuits are generated by flexible, motile, and sequential immunological synapses. Immunol Rev. 2013 Jan;251(1):80-96. PubMed PMID: 23278742
  • Jacobelli J, Lindsay RS, Friedman RS. Peripheral tolerance and autoimmunity: lessons from in vivo imaging. Immunol Res. 2013 Mar;55(1-3):146-54. PubMed PMID: 22956468
  • Jacobelli J, Buser AE, Heiden DL, Friedman RS. Autoimmunity in Motion: Mechanisms of immune regulation and destruction revealed by in vivo imaging. Immunological Reviews, in press.
  • Whitesell JC, Lindsay RS, Olivas-Corral JG, Yannacone SF, Schoenbach M, Lucas ED, Friedman RS. Islet lymphocytes maintain a stable regulatory phenotype under homeostatic conditions and metabolic stress. In submission.
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Practice Locations

UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

General Information

Department: Immunology and Microbiology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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