Nicholas Walter, MD

Publications

• Walter ND, Strong M, Belknap R, Ordway D, Daley, Chan ED. Translating basic science into public health action for multidrug- and extensively drug resistant-tuberculosis. Respirology IN PRESS
• Willis, M, Winston CA, Helig CM, Cain KP, Walter ND, MacKenzie WR. Seasonality of tuberculosis in the United States, 1993-2008. Clin Infect Dis IN PRESS
• Davis JL, Dowdy DW, den Boon S, Walter ND, Katamba A, Cattamanchi A "Test and Treat: A New Standard for Smear-Positive Tuberculosis." JAIDS Journal of Acquired Immune Deficiency Syndromes 2012 61(1): e6-e8
• Kalema N, den Boon S, Cattamanchi A, Davis JL, Alfred A, Katagira W, Everett C, Walter ND, Byanyima P, Kaswabuli S, Yoo S , Worodria W, Huang L Oral antimicrobial rinse to reduce mycobacterial culture contamination among tuberculosis suspects in Uganda: A prospective study PLoS ONE 7(7): e38888.
• Walter ND, Bemis L, Edwards M, Ovrutsky AR, Chan ED. Need for rigor in design, reporting and interpretation of transcriptomic biomarker studies J Clin Microbiol. 2012 Dec;50(12):4190-1
• Walter ND, Painter J, Parker M, Lowenthal P, Flood J, Fu Y, Asis R, Reves R, Tuberculosis Epidemiologic Studies Consortium. Persistent latent tuberculosis reactivation risk in United States immigrants. Am J Respir Crit Care Med. 2014 Jan 1;189(1):88-95. PubMed PMID: 24308495
• Cattamanchi A, Walter ND, Metcalfe JZ, Davis JL. A transcriptional signature for active TB: have we found the needle in the haystack?. PLoS Med. 2013 Oct;10(10):e1001539. PubMed PMID: 24167454
• Dowdy DW, Davis JL, den Boon S, Walter ND, Katamba A, Cattamanchi A. Population-level impact of same-day microscopy and Xpert MTB/RIF for tuberculosis diagnosis in Africa. PLoS One. 2013;8(8):e70485. PubMed PMID: 23950942
• Andama AO, den Boon S, Meya D, Cattamanchi A, Worodria W, Davis JL, Walter ND, Yoo SD, Kalema N, Haller B, Huang L, International HIV-Associated Opportunistic Pneumonias (IHOP) Study. Prevalence and outcomes of cryptococcal antigenemia in HIV-seropositive patients hospitalized for suspected tuberculosis in Uganda. J Acquir Immune Defic Syndr. 2013 Jun 1;63(2):189-94. PubMed PMID: 23542636
• Garcia B, Walter ND, Dolganov G, Coram M, Davis JL, Schoolnik GK, Strong M. A minimum variance method for genome-wide data-driven normalization of quantitative real-time polymerase chain reaction expression data. Anal Biochem. 2014 Aug 1;458:11-3. PubMed PMID: 24780223
• Walter ND, Painter J, Parker M, Lowenthal P, Flood J, Fu Y, Asis R, Reves R, Tuberculosis Epidemiologic Studies Consortium. Persistent latent tuberculosis reactivation risk in United States immigrants. Am J Respir Crit Care Med. 2014 Jan 1;189(1):88-95. PubMed PMID: 24308495
• Walter ND, Miller MA, Vasquez J, Weiner M, Chapman A, Engle M, Higgins M, Quinones AM, Roselli V, Canono E, Yoon C, Cattamanchi A, Davis JL, Phang T, Stearman RS, Datta G, Garcia BJ, Daley CL, Strong M, Kechris K, Fingerlin TE, Reves R, Geraci MW. Blood transcriptional biomarkers for active TB among US patients: A case-control study with systematic cross-classifier evaluation. J Clin Microbiol. 2015 Nov 18. [Epub ahead of print] PubMed PMID: 26582831
• Aiona K, Lowenthal P, Painter JA, Reves R, Flood J, Parker M, Fu Y, Wall K, Walter ND. Transnational Record Linkage for Tuberculosis Surveillance and Program Evaluation. Public Health Rep. 2015 Sep-Oct;130(5):475-84. PubMed PMID: 26327726
• Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL. Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis. J Infect Dis. 2015 Sep 15;212(6):990-8. PubMed PMID: 25762787
• Garcia BJ, Loxton AG, Dolganov GM, Van TT, Davis JL, de Jong BC, Voskuil MI, Leach SM, Schoolnik GK, Walzl G, Strong M, Walter ND. Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients. Tuberculosis (Edinb). 2016 Sep;100:89-94. PubMed PMID: 27553415
• Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. J Infect Dis. 2016 Oct 15;214(8):1205-11. PubMed PMID: 27534685
• Walter ND, Reves R, Davis JL. Blood transcriptional signatures for tuberculosis diagnosis: a glass half-empty perspective. Lancet Respir Med. 2016 Jun;4(6):e28. PubMed PMID: 27304799
• Katagira W, Walter ND, Den Boon S, Kalema N, Ayakaka I, Vittinghoff E, Worodria W, Cattamanchi A, Huang L, Davis JL. Empiric TB Treatment of Severely Ill Patients With HIV and Presumed Pulmonary TB Improves Survival. J Acquir Immune Defic Syndr. 2016 Jul 1;72(3):297-303. PubMed PMID: 26918546
• Walter ND, Miller MA, Vasquez J, Weiner M, Chapman A, Engle M, Higgins M, Quinones AM, Rosselli V, Canono E, Yoon C, Cattamanchi A, Davis JL, Phang T, Stearman RS, Datta G, Garcia BJ, Daley CL, Strong M, Kechris K, Fingerlin TE, Reves R, Geraci MW. Blood Transcriptional Biomarkers for Active Tuberculosis among Patients in the United States: a Case-Control Study with Systematic Cross-Classifier Evaluation. J Clin Microbiol. 2016 Feb;54(2):274-82. PubMed PMID: 26582831
• Ofori-Anyinam B, Dolganov G, Van T, Davis JL, Walter ND, Garcia BJ, Voskuil M, Fissette K, Diels M, Driesen M, Meehan CJ, Yeboah-Manu D, Coscolla M, Gagneux S, Antonio M, Schoolnik G, Gehre F, de Jong BC. Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum. Tuberculosis (Edinb). 2017 May;104:58-64. PubMed PMID: 28454650
• Zhao X, Epperson LE, Hasan NA, Honda JR, Chan ED, Strong M, Walter ND, Davidson RM. Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample. Genome Announc. 2017 Apr 20;5(16). PubMed PMID: 28428297
• Voskuil MI, Covey CR, Walter ND. Antibiotic Lethality and Membrane Bioenergetics. Adv Microb Physiol. 2018;73:77-122. PubMed PMID: 30262111
• Walter ND, Moore CM, Kayigire XA, Dide-Agossou C, Worodria W, Huang L, Everett CK, Schoolnik GS, Nahid P, Davis JL. Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum. BMC Infect Dis. 2018 Jul 3;18(1):293. PubMed PMID: 29970012
• Goletti D, Lee MR, Wang JY, Walter N, Ottenhoff THM. Update on tuberculosis biomarkers: From correlates of risk, to correlates of active disease and of cure from disease. Respirology. 2018 May;23(5):455-466. PubMed PMID: 29457312
• Ofori-Anyinam B, Dolganov G, Van T, Davis JL, Walter ND, Garcia BJ, Voskuil M, Fissette K, Diels M, Driesen M, Meehan CJ, Yeboah-Manu D, Coscolla M, Gagneux S, Antonio M, Schoolnik G, Gehre F, de Jong BC. Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum. Tuberculosis (Edinb). 2017 May;104:58-64. PubMed PMID: 28454650
• Zhao X, Epperson LE, Hasan NA, Honda JR, Chan ED, Strong M, Walter ND, Davidson RM. Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample. Genome Announc. 2017 Apr 20;5(16). PubMed PMID: 28428297

Practice Locations

• University of Colorado Hospital

Specialty Information

• Internal Medicine, Board Certification
• Pulmonary Disease and Critical Care Medicine, Board Certification

• Critical Care
• Lungs and Breathing