Wendy Tzou, MD, FACC, FHRS

Professional Titles

• Director, Cardiac Electrophysiology
• Director, Cardiology Platinum Service

Recognitions

• 5280 Top Doctor, 5280 Magazine (2020)
• 5280 Top Doctor, 5280 Magazine (2019)
• 5280 Top Doctor, 5280 Magazine (2017)

Publications

• Fleeman BE, Beldner SJ, Katz DF, Steckman DA, Aleong RA, Nguyen DT, Schuller JL, Sung RK, Tzou WS, Varosy PD, Sauer WH. Incidence and Predictors of Pleuritic Chest Discomfort Following Ablation of Atrial Fibrillation. American College of Cardiology Scientific Sessions 2013. San Francisco, CA.
• Aleong R, Varosy P, Tzou W, Sung R, Nguyen DT, Schuller J, Katz D, Steckman D, Sauer W. Single Beat Resetting Response can be used Instead of Entrainment to Identify Proximity to an Arrhythmia Circuit. American College of Cardiology Scientific Sessions 2013. San Francisco, CA.
• Heath RR, Nguyen DT, Tzou WS, Sauer WH. Bicuspid Ventricular Tachycardia in a Patient with Syncope and a Structurally Normal Heart. Cardiac Electrophysiology Clinics 2012;4(4)
• Abularach ME, Campos B, Park KM, Tschabrunn CM, Frankel DS, Park RE, Gerstenfeld EP, Mountantonakis S, Garcia FC, Dixit S, Tzou WS, Hutchinson MD, Lin D, Riley MP, Cooper JM, Bala R, Callans DJ, Marchlinski FE. Ablation of ventricular arrhythmias arising near the anterior epicardial veins from the left sinus of Valsalva region: ECG features, anatomic distance, and outcome. Heart Rhythm. 2012 Feb 2. [Epub ahead of print]
• Saghy L, Callans DJ, Garcia F, Lin D, Marchlinski FE, Riley M, Dixit S, Tzou WS, Haqqani HM, Pap R, Kim S, Gerstenfeld EP. Is there a relationship between complex fractionated atrial electrograms recorded during atrial fibrillation and sinus rhythm fractionation? Heart Rhythm. 2012 Feb;9(2):181-8. Epub 2011 Sep 23
• Bala R, Ren JF, Hutchinson MD, Desjardins B, Tschabrunn C, Gerstenfeld EP, Deo R, Dixit S, Garcia FC, Cooper J, Lin D, Riley MP, Tzou WS, Verdino R, Epstein AE, Callans DJ, Marchlinski FE. Assessing epicardial substrate using intracardiac echocardiography during VT ablation. Circ Arrhythm Electrophysiol. 2011 Oct;4(5):667-73. Epub 2011 Aug 31.
• Tzou WS, Zado ES, Lin D, Callans DJ, Dixit S, Cooper JM, Bala R, Garcia F, Hutchinson MD, Riley MP, Deo R, Gerstenfeld EP, Marchlinski FE. Sinus rhythm ECG criteria associated with basal-lateral ventricular tachycardia substrate in patients with nonischemic cardiomyopathy. J Cardiovasc Electrophysiol. 2011 Dec;22(12):1351-8. doi: 10.1111/j.1540-8167.2011.02129.x. Epub 2011 Jul 7.
• Tzou WS, Sághy L, Lin D.Termination of persistent atrial fibrillation during left atrial mapping.J Cardiovasc Electrophysiol. 2011 Oct;22(10):1171-3.
• Haqqani HM, Tschabrunn CM, Tzou WS, Dixit S, Cooper JM, Riley MP, Lin D, Hutchinson MD, Garcia FC, Bala R, Verdino RJ, Callans DJ, Gerstenfeld EP, Zado ES, Marchlinski FE. Isolated septal substrate for ventricular tachycardia in nonischemic dilated cardiomyopathy: incidence, characterization, and implications. Heart Rhythm. 2011 Aug;8(8):1169-76.
• Tzou WS and Marchlinski FE. Ventricular Tachycardia with Heart Disease. Ed. Saksena S. Interventional Cardiac Electrophysiology. Cardiotext Pub. In Press
• Tzou WS and Marchlinski FE. How To Map and Ablate Unstable VT (Penn Approach). Eds. Hsia H, Marchlinski FE, Callans DJ, Oseroff O, Wang P, Natale A, Thakur RK, Al-Ahmad A. Hands-on Ablation: The Experts' Approach. Cardiotext Pub. In Press
• Tzou WS and Marchlinski FE. Epicardial Ablation. Ed Saksena S. Interventional Cardiac Electrophysiology. Cardiotext Pub. In press
• Campos B, Jauregui ME, Park KM, Mountantonakis SE, Gerstenfeld EP, Haqqani H, Garcia FC, Hutchinson MD, Callans DJ, Dixit S, Lin D, Riley MP, Tzou W, Cooper JM, Bala R, Zado ES, Marchlinski FE. New unipolar electrogram criteria to identify irreversibility of nonischemic left ventricular cardiomyopathy. J Am Coll Cardiol. 2012 Nov 20;60(21):2194-204.
• Betensky BP, Deyell MW, Tzou WS, Zado ES, Marchlinski FE. Sinus rhythm electrocardiogram identification of basal-lateral ischemic versus nonischemic substrate in patients with ventricular tachycardia. J Interv Card Electrophysiol. 2012 Dec;35(3):311-21.
• Haqqani HM, Tschabrunn CM, Betensky BP, Lavi N, Tzou WS, Zado ES, Marchlinski FE. Layered activation of epicardial scar in arrhythmogenic right ventricular dysplasia: possible substrate for confined epicardial circuits. Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):796-803.
• Tzou WS, Nguyen DT, Aleong RG, Varosy PD, Katz DF, Heath RR, Schuller JL, Lowery CM, Lewkowiez L, Sauer WH. Endocardial Electrogram Characteristics of Epicardial Ventricular Arrhythmias. J Cardiovasc Electrophysiol. 2013 Jan 14. doi: 10.1111/jce.12096. [Epub ahead of print]
• Lowery CM, Tzou WS, Aleong RG, Nguyen DT, Varosy PD, Katz DF, Heath RR, Schuller JL, Lewkowiez L, Sauer WH. Use of stored implanted cardiac defibrillator electrograms in catheter ablation of ventricular fibrillation. Pacing Clin Electrophysiol. 2013 Jan;36(1):76-85.
• Tzou WS, Foley TR, Nguyen DT, Aleong R. Infra-Hisian Atrio-Ventricular Block. Cardiac Electrophysiology Clinics 2012;4(4)
• Tzou WS. Wide Complex Tachycardia Following Valve Surgery. Cardiac Electrophysiology Clinics 2012;4(4)
• Steckman D, Heath R, Katz DF, Gonzalez JE, Zipse M, Sung RK, Varosy PD, Aleong RG, Nguyen DT, Schuller JL, Sauer WH, and Tzou WS. Successful Ablation of Premature Atrial Contractions Originating from the Left Coronary Cusp. Heart Rhythm Scientific Sessions 2013, Denver, CO.
• Frankel DS, Garcia F, Santangeli P, Tzou WS, Sauer WH, Marchlinski FE. Ventricular Tachycardia Core Isolation with Demonstration of Entrance and Exit Block. Heart Rhythm. 2014; 11 (5S): S529
• Hegeman TW, Katz DF, Sauer WH, Tzou WS. Multifaceted approach to successful ablation in a patient with ventricular tachycardia storm. Heart Rhythm; 11 (5S): S540
• Steckman D, Frasier R, Zipse M, Gonzalez J, Katz D, Tompkins C, Tzou W, Nguyen D, Varosy P, Sauer W, Sung R. QRS narrowing immediately post cardiac resynchronization therapy predicts ventricular tachycardia. Heart Rhythm; 11 (5S): S404-S405
• Zipse MM, Sauer WH, Gonzalez J, Steckman D, Varosy P, Katz D, Kay J, Tompkins C, Sung R, Tzou W, Schuller J, Nguyen D. Patients with Tetralogy of Fallot and ICDs have a high incidence of late reduction of sensed R waves. Heart Rhythm; 11 (5S): S93
• Katz DF, Turakhia MP, Varosy PD, Tzou WS, Sauer WH, Aleong RG, Nguyen D, Kao DP. In-hospital complications associated with catheter ablation of ventricular tachycardia: An analysis of 9,699 procedures. Heart Rhythm; 11 (5S): S435
• Nguyen DT, Barham W, Zheng L, Dinegar S, Tzou WS, Sauer WH. Effect of radiofrequency energy delivery in proximity to metallic medical device components.Heart Rhythm. 2015 Oct;12(10):2162-9.
• Tung R, Vaseghi M, Frankel DS, Vergara P, Di Biase L, Nagashima K, Yu R, Vangala S, Tseng CH, Choi EK, Khurshid S, Patel M, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Vakil K, Tedrow U, Burkhardt JD, Tholakanahalli VN, Saliaris A, Dickfeld T, Weiss JP, Bunch TJ, Reddy M, Kanmanthareddy A, Callans DJ, Lakkireddy D, Natale A, Marchlinski F, Stevenson WG, Della Bella P, Shivkumar K. Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study.Heart Rhythm. 2015 Sep;12(9):1997-2007.
• Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP.Safety of ventricular tachycardia ablation in clinical practice: findings from 9699 hospital discharge records.Circ Arrhythm Electrophysiol. 2015 Apr;8(2):362-70.
• Tzou WS, Frankel DS, Hegeman T, Supple GE, Garcia FC, Santangeli P, Katz DF, Sauer WH, Marchlinski FE. Core isolation of critical arrhythmia elements for treatment of multiple scar-based ventricular tachycardias.Circ Arrhythm Electrophysiol. 2015 Apr;8(2):353-61
• Hegeman TW, Tzou WS, Katz DF, Sung RK, Sauer WH. Proximal left fascicular ablation can eliminate ventricular fibrillation and polymorphic ventricular tachycardia triggered by multifocal fascicular ectopy. Heart Rhythm; 11 (5S): S494
• Tzou WS, Hegeman T, Frankel DS, Sauer WH, Marchlinski FE. Anatomic isolation of core elements of circuit substrate with ablation eliminates multiple scar based ventricular tachycardias. Circulation. 2014;130:A19032
• Gonzalez JE, Tzou W, Sauer WH, Nguyen DT.Ventricular Tachycardia in a Patient with Biventricular Noncompaction.Card Electrophysiol Clin. 2016 Mar;8(1):139-44.
• Borne RT, Peterson PN, Greenlee R, Heidenreich PA, Wang Y, Curtis JP, Tzou WS, Varosy PD, Kremers MS, Masoudi FA. Temporal Trends in Patient Characteristics and Outcomes Among Medicare Beneficiaries Undergoing Primary Prevention Implantable Cardioverter-Defibrillator Placement in the United States, 2006–2010: Results from the National Cardiovascular Data Registry’s Implantable Cardioverter-Defibrillator Registry. Circulation. 2014;130:845-853.
• Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP.Safety of Ventricular Tachycardia Ablation in Clinical Practice: Findings from 9,699 Hospital Discharge Records.Circ Arrhythm Electrophysiol. Accepted
• Tzou WS, Frankel DS, Hegeman T, Supple GE, Garcia FC, Santangeli P, Katz DF, Sauer WH, Marchlinski FE.Core Isolation of Critical Arrhythmia Elements for Treatment of Multiple Scar-Based Ventricular Tachycardias.Circ Arrhythm Electrophysiol. Accepted
• Nguyen DT, Barham W, Zheng L, Shillinglaw B, Tzou WS, Neltner B, Mestroni L, Bosi S, Ballerini L, Prato M, Sauer WH.Carbon nanotube facilitation of myocardial ablation with radiofrequency energy.J Cardiovasc Electrophysiol. 2014 Dec;25(12):1385-90.
• Tzou WS, Tung R, Frankel DS, Vaseghi M, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy D, Dickfeld T, Saliaris A, Weiss JP, Mathuria N, Tedrow U, Afzal MR, Vergara P, Nagashima K, Patel M, Nakahara S, Vakil K, Burkhardt JD, Tseng CH, Natale A, Shivkumar K, Callans DJ, Stevenson WG, Della Bella P, Marchlinski FE, Sauer WH. Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis. Circ Arrhythm Electrophysiol. 2017 Jan;10(1). PubMed PMID: 28082527
• Zipse MM, Schuller JL, Steckman DS, Katz DF, Tzou WS, Nguyen DT, Aleong RG, Sung RK, Tompkins C, Varosy PD, Sauer WH. Measured lead parameters and electrogram sensing over time in patients with cardiac sarcoidosis and an implanted cardiac defibrillator. JACCCEP 2015
• Zipse MM, Tzou WS. Resynchronization Therapy in Cardiac Sarcoidosis and Severe Heart Failure: When Good May Not Be Good Enough. J Cardiovasc Electrophysiol. 2016 Dec 7. [Epub ahead of print] PubMed PMID: 27925330
• Sauer WH, Steckman DS, Zipse MM, Tzou WS, Aleong RG. High Power Bipolar Ablation for Incessant Ventricular Tachycardia Utilizing a Deep Mid-Myocardial Septal Circuit. Heart Rhythm Case Reports 2015 (in press)
• Nguyen DT, Tzou WS, Brunnquell M, Zipse M, Schuller JL, Zheng L, Aleong RA, Sauer WH. Clinical and biophysical evaluation of variable bipolar configurations during radiofrequency ablation for treatment of ventricular arrhythmias. Heart Rhythm. 2016 Nov;13(11):2161-2171. PubMed PMID: 27424078
• Frankel DS, Tung R, Santangeli P, Tzou WS, Vaseghi M, Di Biase L, Nagashima K, Tedrow U, Bunch TJ, Tholakanahalli VN, Dendi R, Reddy M, Lakkireddy D, Dickfeld T, Weiss JP, Mathuria N, Vergara P, Patel M, Nakahara S, Vakil K, Sauer WH, Callans DJ, Natale A, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE. Sex and Catheter Ablation for Ventricular Tachycardia: An International Ventricular Tachycardia Ablation Center Collaborative Group Study. JAMA Cardiol. 2016 Nov 1;1(8):938-944. PubMed PMID: 27556589
• Nguyen DT, Barham W, Zheng L, Dinegar S, Tzou WS, Sauer WH. Effect of Radiofrequency Energy Delivery in Proximity to Metallic Medical Device Components. Circulation: Arrhythmia and Electrophysiology 2015 (in press)
• Flint K, Tzou WS. Pacing-Induced Cardiomyopathy: "It's Tough to Make Predictions, Especially About the Future"*. J Cardiovasc Electrophysiol. 2016 Oct;27(10):1180-1182. PubMed PMID: 27502329
• Gonzalez JE, Tzou W, Sauer WH, Nguyen DT. Ventricular Tachycardia in a Patient with Bi-Ventricular Non-Compaction. Cardiac Electrophysiology Clinics 2015 (in press)
• Nguyen DT, Tzou WS, Zheng L, Barham W, Schuller JL, Shillinglaw B, Quaife RA, Sauer WH. Enhanced Radiofrequency Ablation With Magnetically Directed Metallic Nanoparticles. Circ Arrhythm Electrophysiol. 2016 May;9(5). PubMed PMID: 27162034
• Zipse MM, Gonzalez JE, Sauer WH, Tzou W. Bipolar Ablation of Right Ventricular Papillary Muscle Premature Ventricular Contractions. Cardiac Electrophysiology Clinics 2015 (in press).
• Steckman DA, Frasier R, Zipse M, Gonzalez J, Katz D, Schuller J, Tzou W, Tompkins C, Nguyen DT, Varosy P, Sauer W, Sung R. Change in QRS Duration Over Time Predicts Ventricular Tachycardia after Cardiac Resynchronization Therapy. Journal of Cardiac Failure 2014; 20 (8), S36
• Gonzalez JE, Tzou W, Sauer WH, Nguyen DT. Ventricular Tachycardia in a Patient with Biventricular Noncompaction. Card Electrophysiol Clin. 2016 Mar;8(1):139-44. PubMed PMID: 26920182
• Aleong RG, Tompkins C, Varosy PD, Tzou WS, Katz DF, Schuller JL, Sung RK, Nguyen D, Sauer WH, Kao DP. Analysis of Outcomes in 8,304 Patients Undergoing Lead Extraction for Infection. Heart Rhythm 2015
• Aleong RG, Tompkins C, Varosy PD, Katz DF, Schuller JL, Nguyen D, Tzou WS, Sung RK, Sauer WH, Kao DP. Risk Score to Predict Adverse Events in 57,220 patients Undergoing Lead Extraction. Heart Rhythm 2015
• Zipse MM, Hamilton N, Seres T, Tzou WS, Messenger J, Carroll J, Sauer WH. Transcatheter Right Ventricular Occlusion for Treatment of Cardiac Perforation. Heart Rhythm 2015
• Barham WY, Nguyen D, Zheng L, Tzou WS, Sauer WH. Presence of Esophageal Temperature Probes Increases Temperatures of Adjacent, Non-Targeted Tissues during Radiofrequency Ablation. Heart Rhythm 2015
• Sandhu A, Tzou W, Ream K, Valle J, Tompkins C, Nguyen DT, Sauer WH, Carroll JD, Messenger J, Aleong RG. Heart Block After Discharge in Patients Undergoing TAVR With Latest-Generation Valves. J Am Coll Cardiol. 2018 Feb 6;71(5):577-578. PubMed PMID: 29406864
• Vakil K, Garcia S, Tung R, Vaseghi M, Tedrow U, Della Bella P, Frankel DS, Vergara P, Di Biase L, Nagashima K, Nakahara S, Tzou WS, Burkhardt JD, Dickfeld T, Weiss JP, Bunch J, Callans D, Lakkireddy D, Natale A, Sauer WH, Stevenson WG, Marchlinski F, Shivkumar K, Tholakanahalli VN. Ventricular Tachycardia Ablation in the Elderly: An International Ventricular Tachycardia Center Collaborative Group Analysis. Circ Arrhythm Electrophysiol. 2017 Dec;10(12). PubMed PMID: 29254946
• Zipse MM, Gonzalez JE, Marzec L, Sauer WH, Tzou WS. Bipolar Ablation of Right Ventricular Papillary Muscle PVCs. Heart Rhythm 2015
• Doherty JU, Kort S, Mehran R, Schoenhagen P, Soman P, Dehmer GJ, Doherty JU, Schoenhagen P, Amin Z, Bashore TM, Boyle A, Calnon DA, Carabello B, Cerqueira MD, Conte J, Desai M, Edmundowicz D, Ferrari VA, Ghoshhajra B, Mehrotra P, Nazarian S, Reece TB, Tamarappoo B, Tzou WS, Wong JB, Doherty JU, Dehmer GJ, Bailey SR, Bhave NM, Brown AS, Daugherty SL, Dean LS, Desai MY, Duvernoy CS, Gillam LD, Hendel RC, Kramer CM, Lindsay BD, Manning WJ, Mehrotra P, Patel MR, Sachdeva R, Wann LS, Winchester DE, Wolk MJ, Allen JM. ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for Multimodality Imaging in Valvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. J Am Soc Echocardiogr. 2017 Oct 20. [Epub ahead of print] PubMed PMID: 29066081
• Nguyen D, Olson MD, Zheng L, Barham WY, Tzou WS, Sauer WH. Irrigant Ionic Concentration and Catheter Positioning Affect Radiofrequency Ablation Lesions. Heart Rhythm 2015
• Borne R, Tzou WS, Sauer WH, Babu A, Tompkins C. Multidisciplinary Management of End-Stage Heart Failure and VT Storm: VT Ablation at the time of LVAD Implantation. Heart Rhythm 2015
• Lip GYH, Coca A, Kahan T, Boriani G, Manolis AS, Olsen MH, Oto A, Potpara TS, Steffel J, Marín F, de Oliveira Figueiredo MJ, de Simone G, Tzou WS, Chiang CE, Williams B, Dan GA, Gorenek B, Fauchier L, Savelieva I, Hatala R, van Gelder I, Brguljan-Hitij J, Erdine S, Lovic D, Kim YH, Salinas-Arce J, Field M. Hypertension and cardiac arrhythmias: a consensus document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE). Europace. 2017 Jun 1;19(6):891-911. PubMed PMID: 28881872
• Nguyen D, Zheng L, Barham W, Tzou WS, Dinegar S, Sauer WH. Effect of Radiofrequency Energy Delivery in Proximity to Metallic Medical Device Components. Heart Rhythm 2015
• Tompkins C, Varosy PD, Tzou WS, Aleong RG, Nguyen D, Katz DF, Schuller JL, Sung RK, Sauer WH, Kao DP. Gender Differences in Procedure-related Complications Following Ablation for Ventricular Tachycardia. Heart Rhythm 2015
• Zipse MM, Steckman D, Schuller JL, Katz DF, Tzou WS, Nguyen D, Gonzalez JE, Marzec L, Weinberger H, Hamzeh N, Sauer WH. Prognostic Value of Programmed Ventricular Stimulation in Patients Evaluated for Cardiac Sarcoidosis. Heart Rhythm 2015
• Aleong RG, Steckman D, Zipse MM, Tzou WS, Sauer WH. High Power Bipolar Ablation for Incessant Ventricular Tachycardia Utilizing a Deep Mid-Myocardial Septal Circuit. Heart Rhythm 2015
• Vergara P, Tung R, Vaseghi M, Brombin C, Frankel D, Di Biase L, Nagashima K, Tedrow U, Tzou WS, Sauer WH, Mathuria N, Nakahara S, Vakil K, Tholakanahalli V, Bunch TJ, Weiss JP, Dickfeld T, Vunnam R, Lakireddy D, Burkhardt JD, Correra A, Santangeli P, Callans D, Natale A, Marchlinski F, Stevenson WG, Shivkumar K, Della Bella P. Successful ventricular tachycardia ablation in patients with electrical storm reduces recurrences and improves survival. Heart Rhythm. 2018 Jan;15(1):48-55. PubMed PMID: 28843418
• Zipse MM, Tzou WS. Sudden cardiac death in nonischemic cardiomyopathy: Refining risk assessment. J Cardiovasc Electrophysiol. 2017 Nov;28(11):1361-1366. PubMed PMID: 28670752
• Lip GYH, Coca A, Kahan T, Boriani G, Manolis AS, Olsen MH, Oto A, Potpara TS, Steffel J, Marín F, de Oliveira Figueiredo MJ, de Simone G, Tzou WS, En Chiang C, Williams B. Hypertension and cardiac arrhythmias: executive summary of a consensus document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE). Eur Heart J Cardiovasc Pharmacother. 2017 Oct 1;3(4):235-250. PubMed PMID: 28541499
• Tzou WS, Tung R, Frankel DS, Di Biase L, Santangeli P, Vaseghi M, Bunch TJ, Weiss JP, Tholakanahalli VN, Lakkireddy D, Vunnam R, Dickfeld T, Mathuria N, Tedrow U, Vergara P, Vakil K, Nakahara S, Burkhardt JD, Stevenson WG, Callans DJ, Della Bella P, Natale A, Shivkumar K, Marchlinski FE, Sauer WH. Outcomes after repeat ablation of ventricular tachycardia in structural heart disease: An analysis from the International VT Ablation Center Collaborative Group. Heart Rhythm. 2017 Jul;14(7):991-997. PubMed PMID: 28506710
• Santangeli P, Frankel DS, Tung R, Vaseghi M, Sauer WH, Tzou WS, Mathuria N, Nakahara S, Dickfeldt TM, Lakkireddy D, Bunch TJ, Di Biase L, Natale A, Tholakanahalli V, Tedrow UB, Kumar S, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE, Callans DJ. Early Mortality After Catheter Ablation of Ventricular Tachycardia in Patients With Structural Heart Disease. J Am Coll Cardiol. 2017 May 2;69(17):2105-2115. PubMed PMID: 28449770
• Tzou WS, Tung R, Frankel DS, Vaseghi M, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy D, Dickfeld T, Saliaris A, Weiss JP, Mathuria N, Tedrow U, Afzal MR, Vergara P, Nagashima K, Patel M, Nakahara S, Vakil K, Burkhardt JD, Tseng CH, Natale A, Shivkumar K, Callans DJ, Stevenson WG, Della Bella P, Marchlinski FE, Sauer WH. Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis. Circ Arrhythm Electrophysiol. 2017 Jan;10(1). PubMed PMID: 28082527
• Gonzalez JE, Groves DW, Zipse MM, Marzec L, Sung RK, Tompkins C, Katz DF, Schuller JL, Varosy PD, Tzou WS, Aleong RG, Sauer WH, Nguyen D. Epicardial Ablation of Incessant Ventricular Tachycardia in a Patient with Biventricular Non-compaction Cardiomyopathy. Heart Rhythm 2015
• Zipse MM, Tzou WS. Resynchronization Therapy in Cardiac Sarcoidosis and Severe Heart Failure: When Good May Not Be Good Enough. J Cardiovasc Electrophysiol. 2017 Feb;28(2):182-184. PubMed PMID: 27925330
• Tompkins C, Varosy PD, Aleong RG, Sauer WH, Katz DF, Nguyen D, Schuller JL, Sung RK, Tzou WS, Kao DP. Gender Differences in Procedure-related complications following Lead Extraction. Heart Rhythm 2015
• Marzec L, Fraser R, Schneider PM, Varosy PD, Zipse MM, Gonzalez JE, Katz DF, Aleong RG, Tzou WS, Tompkins C, Nguyen D, Schuller JL, Sauer WH, Sung RK. Change in QRS Duration Over Time Predicts Ventricular Tachycardia, Progressive Heart Failure, and Death After Cardiac Resynchronization Therapy. Heart Rhythm 2015
• Borne RT, Katz DF, Tzou WS. Unmasking Chronic Pulmonary Vein Reconnection with Isoproterenol. Heart Rhythm 2015
• Kim RS, Simon S, Powers B, Sandhu A, Sanchez J, Borne RT, Tumolo A, Zipse M, West JJ, Aleong R, Tzou W, Rosenberg MA. Machine Learning Methodologies for Prediction of Rhythm-Control Strategy in Patients Diagnosed With Atrial Fibrillation: Observational, Retrospective, Case-Control Study. JMIR Med Inform. 2021 Dec 6;9(12):e29225. PubMed PMID: 34874889
• Sabzwari SRA, Tzou WS. Systemic Diseases and Heart Block. Card Electrophysiol Clin. 2021 Dec;13(4):721-740. PubMed PMID: 34689899
• Aksu T, De Potter T, John L, Osorio J, Singh D, Alyesh D, Baysal E, Kumar K, Mikaeili J, Dal Forno A, Yalin K, Akdemir B, Woods CE, Salcedo J, Eftekharzadeh M, Akgun T, Sundaram S, Aras D, Tzou WS, Gopinathannair R, Winterfield J, Gupta D, Davila A. Procedural and short-term results of electroanatomic-mapping-guided ganglionated plexus ablation by first-time operators: A multicenter study. J Cardiovasc Electrophysiol. 2022 Jan;33(1):117-122. PubMed PMID: 34674347
• Barrett C, Sandhu A, Tzou W. Electrophysiologic Implications of Transcatheter Aortic Valve Replacement: Incidence, Outcomes, and Current Management Strategies. Curr Cardiol Rep. 2021 Oct 1;23(11):167. PubMed PMID: 34599417
• Al-Ahmad A, Knight B, Tzou W, Schaller R, Yasin O, Padmanabhan D, Zagrodzky J, Bassiouny M, Burkhardt JD, Gallinghouse GJ, Mansour M, McLeod C, Natale A. Evaluation of a novel cardiac signal processing system for electrophysiology procedures: The PURE EP 2.0 study. J Cardiovasc Electrophysiol. 2021 Nov;32(11):2915-2922. PubMed PMID: 34554634
• Varela DL, Rosenberg MA, Borne RT, Sandhu A, Zipse MM, Tzou WS, Sauer WH, Scheinman MM, Nguyen DT. Increased incidence of cavotricuspid isthmus atrial flutter following slow pathway ablation. J Interv Card Electrophysiol. 2021 Sep 17. [Epub ahead of print] PubMed PMID: 34532821
• Kunkel M, Rothstein P, Sauer P, Zipse MM, Sandhu A, Tumolo AZ, Borne RT, Aleong RG, Cleveland JC Jr, Fullerton D, Pal JD, Davies AS, Lane C, Nguyen DT, Sauer WH, Tzou WS. Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools. Heart Rhythm O2. 2021 Jun;2(3):271-279. PubMed PMID: 34337578
• Sanchez JM, Farasat M, Levy AE, Douglas IS, Stauffer BL, Tzou WS, West JJ. A novel approach to electrocardiography in the prone patient. Heart Rhythm O2. 2021 Feb;2(1):107-109. PubMed PMID: 34113910
• Barrett C, Tzou WS. Utility of Intracardiac Echocardiography for Guiding Ablation of Ventricular Tachycardia in Nonischemic Cardiomyopathy. Card Electrophysiol Clin. 2021 Jun;13(2):337-343. PubMed PMID: 33990272
• Tzou W, Sauer W. Letter from the Program Directors. J Innov Card Rhythm Manag. 2021 Apr;12(4):4457-4458. PubMed PMID: 33936860
• Sandhu A, Tzou WS. A Disruptive Technology: Determining Need for Permanent Pacing After TAVR. Curr Cardiol Rep. 2021 Apr 16;23(5):53. PubMed PMID: 33871728
• Sanchez JM, Tzou WS. Amiodarone during ventricular tachycardia ablation: A total eclipse of the heart?. Heart Rhythm. 2021 Jun;18(6):894-895. PubMed PMID: 33753276
• Darden D, Hsu JC, Tzou WS, von Alvensleben JC, Brooks M, Hoffmayer KS, Brambatti M, Sauer WH, Feld GK, Adler E. Fasciculoventricular and atrioventricular accessory pathways in patients with Danon disease and preexcitation: A multicenter experience. Heart Rhythm. 2021 Jul;18(7):1194-1202. PubMed PMID: 33737230
• Zghaib T, Allison JD, Barrett C, Arkles J, D'Souza B, Luebbert J, Garcia F, Heist EK, Tzou W, Callans D, Marchlinski FE, Frankel DS. Multicenter experience with andexanet alfa for refractory pericardial bleeding during catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2023 Jan 4. [Epub ahead of print] PubMed PMID: 36598431
• Tschabrunn CM, Tzou WS. The Evolution of Ventricular Scar Substrate Assessment by Using High-Resolution Mapping Platforms: Ongoing Quest for "Ground Truth". JACC Clin Electrophysiol. 2021 Feb;7(2):206-209. PubMed PMID: 33602401
• Scott M, Baykaner T, Bunch TJ, Piccini JP, Russo AM, Tzou WS, Zeitler EP, Steinberg BA. Contemporary Trends in Cardiac Electrophysiology Procedures in the United States, and Impact of a Global Pandemic. Heart Rhythm O2. 2022 Dec 21. [Epub ahead of print] PubMed PMID: 36569386
• Cerbin L, Tzou WS. Open-irrigation for radiofrequency ablation for atrial fibrillation: Worth its salt?. J Cardiovasc Electrophysiol. 2021 Apr;32(4):982-983. PubMed PMID: 33556989
• Amin DR, Behan S, Pengshung M, Khanna A, Tzou WS, Mantini N, Henao-Martinez AF, Tumolo A, Groves DW. Sustained monomorphic ventricular tachycardia as the presenting sign of Chagas' cardiomyopathy in a low prevalence setting, diagnosis and management challenges. A case report. Ther Adv Infect Dis. 2022 Jan-Dec;9:20499361221141772. PubMed PMID: 36506697
• Sandhu A, Varosy PD, Du C, Aleong RG, Tumolo AZ, West JJ, Tzou WS, Curtis JP, Freeman JV, Friedman DJ, Hess PL. Device-Sizing and Associated Complications With Left Atrial Appendage Occlusion: Findings From the NCDR LAAO Registry. Circ Cardiovasc Interv. 2022 Dec;15(12):e012183. PubMed PMID: 36472194
• Piccini JP, Russo AM, Sharma PS, Kron J, Tzou W, Sauer W, Park DS, Birgersdotter-Green U, Frankel DS, Healey JS, Hummel J, Koruth J, Linz D, Mittal S, Nair DG, Nattel S, Noseworthy PA, Steinberg BA, Trayanova NA, Wan EY, Wissner E, Zeitler EP, Wang PJ. Advances in Cardiac Electrophysiology. Circ Arrhythm Electrophysiol. 2022 Dec;15(12):e009911. PubMed PMID: 36441565
• Knoepke CE, Wallace BC, Allen LA, Lewis CL, Gupta SK, Peterson PN, Kramer DB, Brancato SC, Varosy PD, Mandrola JM, Tzou WS, Matlock DD. Experiences Implementing a Suite of Decision Aids for Implantable Cardioverter Defibrillators: Qualitative Insights From the DECIDE-ICD Trial. Circ Cardiovasc Qual Outcomes. 2022 Nov;15(11):e009352. PubMed PMID: 36378770
• Aguilar M, Tedrow UB, Tzou WS, Tung R, Frankel DS, Santangeli P, Vaseghi M, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy D, Dickfeld T, Weiss JP, Mathuria N, Vergara P, Nakahara S, Bradfield JS, Burkhardt JD, Stevenson WG, Callans DJ, Della Bella P, Natale A, Shivkumar K, Marchlinski FE, Sauer WH. Catheter ablation of ventricular tachycardia in patients with prior cardiac surgery: An analysis from the International VT Ablation Center Collaborative Group. J Cardiovasc Electrophysiol. 2021 Feb;32(2):409-416. PubMed PMID: 33355965
• Sandhu A, Tzou WS, Borne RT, Zipse MM, Nguyen DT, Sauer WH. Uncovering a unique path: Antidromic AVRT utilizing a left anteroseptal Mahaim-like accessory pathway. Pacing Clin Electrophysiol. 2021 Jan;44(1):185-188. PubMed PMID: 32794265
• Varela DL, Rosenberg MA, Borne RT, Sandhu A, Zipse MM, Tzou WS, Sauer WH, Scheinman MM, Nguyen DT. Increased incidence of cavotricuspid isthmus atrial flutter following slow pathway ablation. J Interv Card Electrophysiol. 2022 Apr;63(3):581-589. PubMed PMID: 34532821
• Edward JA, Chang SC, Gill EA, Tzou WS, Aleong RG. Esophago-Pericardial Fistula as a Rare and Life-Threatening Complication of Epicardial Ventricular Tachycardia Ablation. JACC Case Rep. 2022 Sep 21;4(18):1180-1185. PubMed PMID: 36213880
• Howard B, Verma A, Tzou WS, Mattison L, Kos B, Miklavcic D, Onal B, Stewart MT, Sigg DC. Effects of Electrode-Tissue Proximity on Cardiac Lesion Formation Using Pulsed Field Ablation. Circ Arrhythm Electrophysiol. 2022 Oct;15(10):e011110. PubMed PMID: 36166690
• Tzou WS. Insights From the Dilated Cardiomyopathy Ventricular Tachycardia Ablation Study: Wisdom Through Humility. J Am Coll Cardiol. 2022 Sep 13;80(11):1057-1059. PubMed PMID: 36075674
• Garg L, Tzou WS. A Force Awakens: Return of Needle Catheter Radiofrequency Ablation for Targeting Intramural Ventricular Arrhythmias. Circ Arrhythm Electrophysiol. 2022 Sep;15(9):e011309. PubMed PMID: 36006297
• Sabzwari SRA, Rosenberg MA, Mann J, Cerbin L, Barrett C, Garg L, Aleong RG, Sandhu A, West J, Tumolo AZ, Varosy PD, Sauer WH, Zipse MM, Tzou WS. Limitations of Unipolar Signals in Guiding Successful Outflow Tract Premature Ventricular Contraction Ablation. JACC Clin Electrophysiol. 2022 Jul;8(7):843-853. PubMed PMID: 35643806
• Markman TM, John L, Kalluri AG, Tzou WS, Badertscher P, Winterfield J, Partington SL, Santangeli P, Chung FP. Catheter Ablation of Ventricular Arrhythmias With Indirect Evidence of Critical Substrate Elements Protected by Prosthetic Material. JACC Clin Electrophysiol. 2022 May;8(5):677-679. PubMed PMID: 35589181
• Barrett C, Tzou WS. Endocardial and Epicardial Scar Homogenization: Is It Time to See the Light?. JACC Clin Electrophysiol. 2022 Apr;8(4):462-464. PubMed PMID: 35450600
• Aksu T, De Potter T, John L, Osorio J, Singh D, Alyesh D, Baysal E, Kumar K, Mikaeili J, Dal Forno A, Yalin K, Akdemir B, Woods CE, Salcedo J, Eftekharzadeh M, Akgun T, Sundaram S, Aras D, Tzou WS, Gopinathannair R, Winterfield J, Gupta D, Davila A. Procedural and short-term results of electroanatomic-mapping-guided ganglionated plexus ablation by first-time operators: A multicenter study. J Cardiovasc Electrophysiol. 2022 Jan;33(1):117-122. PubMed PMID: 34674347
• Ashur C, Tzou WS. Learning Before Burning: Mapping With Reversible Pulsed Field Ablation. Circ Arrhythm Electrophysiol. 2024 Feb;17(2):e012430. PubMed PMID: 38284234
• Barrett CD, Nickel A, Rosenberg MA, Ream K, Tzou WS, Aleong R, Tumolo A, Garg L, Zipse M, West JJ, Varosy P, Sandhu A. PRIME score for prediction of permanent pacemaker implantation after transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2023 Dec;102(7):1357-1363. PubMed PMID: 37735946
• Ashur C, Zirille F, Aleong RG, Varosy PD, West JJ, Sandhu A, Tumolo AZ, Rosenberg MA, Sabzwari SRA, Barrett C, Cerbin L, Saqi B, Varela D, Zipse MM, Tzou WS, Garg L. Right versus left-sided implantation of left bundle branch area pacemaker insertion. J Interv Card Electrophysiol. 2023 Sep 21. [Epub ahead of print] PubMed PMID: 37731143
• Huang DT, Gosev I, Wood KL, Vidula H, Stevenson W, Marchlinski F, Supple G, Zalawadiya SK, Weiss JP, Tung R, Tzou WS, Moss JD, Kancharla K, Chaudhry SP, Patel PJ, Khan AM, Schuger C, Rozen G, Kiernan MS, Couper GS, Leacche M, Molina EJ, Shah AD, Lloyd M, Sroubek J, Soltesz E, Shivkumar K, White C, Tankut S, Johnson BA, McNitt S, Kutyifa V, Zareba W, Goldenberg I. Design and characteristics of the prophylactic intra-operative ventricular arrhythmia ablation in high-risk LVAD candidates (PIVATAL) trial. Ann Noninvasive Electrocardiol. 2023 Sep;28(5):e13073. PubMed PMID: 37515396
• Sugrue A, Ibrahim R, Lu M, Bhatia NK, Alkukhun L, Adewumi J, Schaller RD, Marchlinski FE, D'Souza B, Nazer B, Tzou W, Merchant FM, Frankel DS. Impact of Median Sternotomy on Safety and Efficacy of the Subcutaneous Implantable Cardioverter Defibrillator. Circ Arrhythm Electrophysiol. 2023 Aug;16(8):468-474. PubMed PMID: 37485688
• Sabzwari SRA, Tzou WS. Systemic Diseases and Heart Block. Cardiol Clin. 2023 Aug;41(3):429-448. PubMed PMID: 37321693
• Sauer WH, Steiger NA, Tzou WS, Schuller JL, Zheng L, Nguyen DT. Facilitated Myocardial Ablation Using Heat-Sensitive Liposomes Containing Doxorubicin: A Proof-of-Concept Preclinical Study. JACC Clin Electrophysiol. 2023 Aug;9(8 Pt 1):1404-1408. PubMed PMID: 37227346
• Barrett CD, Suzuki Y, Hussein S, Garg L, Tumolo A, Sandhu A, West JJ, Zipse M, Aleong R, Varosy P, Tzou WS, Banaei-Kashani F, Rosenberg MA. Evaluation of Quantitative Decision-Making for Rhythm Management of Atrial Fibrillation Using Tabular Q-Learning. J Am Heart Assoc. 2023 May 2;12(9):e028483. PubMed PMID: 37119087
• Tzou W, Sauer W. Letter from the Program Directors. J Innov Card Rhythm Manag. 2023 Mar;14(3):5384. PubMed PMID: 36998416
• Sandhu A, Holman B, Lammers S, Cerbin L, Barrett C, Sabzwari R, Garg L, Zipse MM, Tumolo AZ, Aleong RG, Von Alvensleben J, Rosenberg M, West JJ, Varosy P, Nguyen DT, Sauer WH, Tzou WS. Evaluating temperature gradients across the posterior left atrium with radiofrequency ablation. J Cardiovasc Electrophysiol. 2023 Apr;34(4):880-887. PubMed PMID: 36682068
• Zghaib T, Allison JD, Barrett C, Arkles J, D'Souza B, Luebbert J, Garcia F, Heist EK, Tzou W, Callans D, Marchlinski FE, Frankel DS. Multicenter experience with andexanet alfa for refractory pericardial bleeding during catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2023 Mar;34(3):593-597. PubMed PMID: 36598431
• Scott M, Baykaner T, Bunch TJ, Piccini JP, Russo AM, Tzou WS, Zeitler EP, Steinberg BA. Contemporary trends in cardiac electrophysiology procedures in the United States, and impact of a global pandemic. Heart Rhythm O2. 2023 Mar;4(3):193-199. PubMed PMID: 36569386

Professional Memberships

• Heart Rhythm Society (HRS), Fellow
• American College of Cardiology, Fellow
• American Heart Association (AHA), Member

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Cardiac Electrophysiology - Anschutz
12505 E. 16th Ave
3rd Floor
Aurora, CO 80045
720-848-6510

Denver Veterans Affairs Medical Center
1055 Clermont St
Denver, CO 80220
1-888-336-8262

Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000

CU Medicine Cardiology - Cherry Creek Medical Center
100 Cook Street
Suite 412
Denver, CO 80206
720-516-9403

Hospital Affiliation

• University of Colorado Hospital
• Veterans Affairs Medical Center
• Denver Health Medical Center

Specialty Information

Specialties

• Cardiac Electrophysiology, Board Certification
• General Cardiology, Board Certification
• Fellow of the American College of Cardiology, Certificate (0001)
• Fellow of the Heart Rythm Society, Certificate (0001)

Conditions & Treatments

• Heart and Circulation
• Heart and Circulation - Arrhythmia
• Heart and Circulation - Heart Diseases