Jen-Ruey Tang, MD

Publications

• Tang JR, Michaelis KA, Nozik-Grayck E, Seedorf G, Hartman-Filson M, Abman SH, Wright CJ. The NF-kB inhibitory proteins IkBa and IkBß mediate disparate responses to inflammation in fetal pulmonary endothelial cells. Accepted for publication, J Immunol, January 2013.
• Azita Jahangirloo, Clyde J Wright, Gregory J Seedorf, Steven H Abman, Jason Gien, Jen-Ruey Tang. Pro-inflammatory Stimuli Cause Injury and Dysfunction of Fetal Pulmonary Vascular Endothelial Cells.
• Tang JR, Michaelis KA, Nozik-Grayck E, Seedorf GJ, Hartman-Filson M, Abman SH, Wright CJ. The NF-?B inhibitory proteins I?Ba and I?Bß mediate disparate responses to inflammation in fetal pulmonary endothelial cells. J Immunol. 2013 Mar 15;190(6):2913-23. PubMed PMID: 23418625
• Azita Jahangirloo, Clyde J Wright, Gregory J Seedorf, Steven H Abman, Jason Gien, and Jen-Ruey Tang. Pro-Inflammatory Stimuli Cause Injury and Dysfunction of Fetal Pulmonary Vascular Endothelial Cells. Presented at PAS 2013 in Washington DC on 5/5/2013 (Publication Number 2920.258).
• Tang JR, Karumanchi SA, Seedorf G, Markham N, Abman SH. Excess soluble vascular endothelial growth factor receptor-1 in amniotic fluid impairs lung growth in rats: linking preeclampsia with bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 302:L36-46, 2012. (PMID: 22003089)
• Wright CJ, Tang JR, Seedorf GJ, Abman SH. Inhibitory-?Bß (I?Bß) mediated NF-?B activation causes fetal pulmonary artery endothelial cell dysfunction following exposure to endotoxin.
• Seedorf GJ, Tang JR, Lich E, Crnich R, Gien J, Balasubramaniam V, Abman SH. Enhanced cGMP signaling through soluble guanylate cyclase (sGC) activation or type 5 phosphodiesterase (PDE5) inhibition preserves vascular and alveolar growth and prevents pulmonary hypertension in experimental bronchopulmonary dysplasia (BPD).