Subbiah Pugazhenthi, PhD
Research Professor, Medicine-Endocrinology/Metabolism/Diabetes

Publications

• Raju RP, Cai L, Tyagi A, Pugazhenthi S. Interactions of Cellular Energetic Gene Clusters in the Alzheimer's Mouse Brain. Mol Neurobiol. 2024 Jan;61(1):476-486. PubMed PMID: 37632678
• Tyagi A, Pugazhenthi S. A Promising Strategy to Treat Neurodegenerative Diseases by SIRT3 Activation. Int J Mol Sci. 2023 Jan 13;24(2). PubMed PMID: 36675125
• Tyagi A, Pugazhenthi S. A Promising Strategy to Treat Neurodegenerative Diseases by SIRT3 Activation. Int J Mol Sci. 2023 Jan 13;24(2). PubMed PMID: 36675125
• Tyagi A, Musa M, Labeikovsky W, Pugazhenthi S. Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer's disease with metabolic syndrome. Sci Rep. 2022 Nov 17;12(1):19808. PubMed PMID: 36396721
• Tyagi A, Mirita C, Shah I, Reddy PH, Pugazhenthi S. Effects of Lipotoxicity in Brain Microvascular Endothelial Cells During Sirt3 Deficiency-Potential Role in Comorbid Alzheimer's Disease. Front Aging Neurosci. 2021;13:716616. PubMed PMID: 34393764
• Tyagi A, Pugazhenthi S. Targeting Insulin Resistance to Treat Cognitive Dysfunction. Mol Neurobiol. 2021 Jun;58(6):2672-2691. PubMed PMID: 33483903
• Tyagi A, Mirita C, Taher N, Shah I, Moeller E, Tyagi A, Chong T, Pugazhenthi S. Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model. Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165849. PubMed PMID: 32485218
• Pugazhenthi S, Qin L, Reddy PH. Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease. Biochim Biophys Acta. 2016 May 6. [Epub ahead of print] PubMed PMID: 27156888
• Qin L, Chong T, Rodriguez R, Pugazhenthi S. Glucagon-Like Peptide-1-Mediated Modulation of Inflammatory Pathways in the Diabetic Brain: Relevance to Alzheimer's Disease. Curr Alzheimer Res. 2016;13(12):1346-1355. PubMed PMID: 27033055
• Pugazhenthi S, Qin L, Bouchard R. Dipeptidyl peptidase-4 inhibition in diabetic rats leads to activation of the transcription factor CREB in ß-cells. Eur J Pharmacol. 2015 Feb 23;755:42-49. [Epub ahead of print] PubMed PMID: 25720341
• Qin L, Bouchard R, Pugazhenthi S. Regulation of cAMP response element binding protein during neuroglial interactions. J Neurochem. 2015 Dec 16. [Epub ahead of print] PubMed PMID: 26677139
• Pugazhenthi S, Qin L, Bouchard R. Dipeptidyl peptidase-4 inhibition in diabetic rats leads to activation of the transcription factor CREB in ß-cells. Eur J Pharmacol. 2015 May 15;755:42-9. PubMed PMID: 25720341
• Geary K, Knaub LA, Schauer IE, Keller AC, Watson PA, Miller MW, Garat CV, Nadeau KJ, Cree-Green M, Pugazhenthi S, Regensteiner JG, Klemm DJ, Reusch JE. Targeting mitochondria to restore failed adaptation to exercise in diabetes. Biochem Soc Trans. 2014 Apr;42(2):231-8. PubMed PMID: 24646223