Adriaan Van Bokhoven, PhD

Lucia MS, van Bokhoven A. Temporal Changes in the Pathologic Assessment of Prostate Cancer. JNCI Monograph, J Natl Cancer Inst Monogr 2012(45):157-61, 2012 [PMID 23271767]

Aimola P, Carmignani M, Volpe AR, Di Benedetto A, Claudio L, Waalkes MP, van Bokhoven A, Tokar EJ, Claudio PP. Cadmium induces p53-dependent apoptosis in human prostate epithelial cells. PLoS One. 2012;7(3):e33647 2012 PMID:22448262

Kristal AR, Till C, Tangen CM, Goodman PJ, Neuhouser ML, Stanczyk FZ, Chu LW, Patel SK, Thompson IM, Reichardt JK, Hoque A, Platz EA, Figg WD, van Bokhoven A, Lippman SM, Hsing AW. Associations of serum sex steroid hormone and 5a-androstane-3a,17ß-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride. Cancer Epidemiol Biomarkers Prev. 10:1823-32. 2012 PMID: 22879203

Infrastructure of the Biospecimen Repository and Associated Core Laboratories. Lucia MS, van Bokhoven A CAP Monographs, In press 2013.

J.R. Diamond, A.C. Tan, T.M. Pitts, A. van Bokhoven , D. Aisner , A.D. Elias, V.F. Borges, K. D. Miller, S.G. Eckhardt, J.J. Tentler. A Phase II Clinical Trial of ENMD-2076 in Metastatic Triple-Negative Breast Cancer: Translating a p53-based Biomarker from Bench to Bedside 11th International Symposium on Targeted Anticancer Therapies (TAT 2013), Paris, France, March 4-6, 2013 #51 2013

Werahera PN, Jasion AE, Liu Y, Daily JW, Nash R, Batte E, Arangua P, La Rosa FG, Maroni PD, Lucia MS, van Bokhoven A, Sullivan HT, Jones C, Lux K, Crawford ED Fluorescence spectroscopy adjutant optical biopsy needle for prostate cancer diagnosis: first-in-human study results 23rd International Prostate Cancer Update, Vail, CO, 2013

Nickel JC, Stephens A, Chen J, Melton-Kreft R, Spirk T, Earl J, O'Toole M, Costerton JW, van Bokhoven A, Mullins C, Ehrlich G Application of State-of-the-Art Methods to Search for Microbial Contributions to the Etiology of Urological Chronic Pelvic Pain Syndrome (UCPPS) American Urological Association Annual Meeting, 4-8 May, 2013 San Diego, CA

Werahera PN, Crawford ED, La Rosa FG, Torkko KC, Schulte B, Sullivan HT, van Bokhoven A, Lucia MS, Kim FJ. Anterior tumors of the prostate: diagnosis and significance. Can J Urol. 2013 Oct;20(5):6897-906. PubMed PMID: 24128826

Nickel JC, Stephens A, Landis JR, Chen J, Mullins C, van Bokhoven A, Lucia MS, Melton-Kreft R, Ehrlich GD, The MAPP Research Network. Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network. J Urol. 2015 Jan 14. [Epub ahead of print] PubMed PMID: 25596358

van Bokhoven, A, Lucia, MS Biorepository Operations and Infrastructure, Chapter in: Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms.

Lucia, MS, van Bokhoven, A. Biorepository Quality Assurance, Chapter in: Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms

Werahera PN, Jasion EA, Crawford ED, La Rosa FG, Lucia MS, van Bokhoven A, Sullivan HT, Port JD, Maroni PD, Daily JW. Systematic diagnosis of prostate cancer using an optical biopsy needle adjunct with fluorescence spectroscopy. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug;2014:2165-8. PubMed PMID: 25570414

Jonscher KR, Osypuk AA, van Bokhoven A, Lucia MS. Evaluation of urinary protein precipitation protocols for the multidisciplinary approach to the study of chronic pelvic pain research network. J Biomol Tech. 2014 Dec;25(4):118-26. PubMed PMID: 25365794

Figg WD, Chau CH, Price DK, Till C, Goodman PJ, Cho Y, Varella-Garcia M, Reichardt JK, Tangen CM, Leach RJ, van Bokhoven A, Thompson IM, Lucia MS. Androgen receptor CAG repeat length and TMPRSS2:ETS prostate cancer risk: results From the Prostate Cancer Prevention Trial. Urology. 2014 Jul;84(1):127-31. PubMed PMID: 24824408

Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ, MAPP Research Network Study Group. The MAPP research network: design, patient characterization and operations. BMC Urol. 2014 Aug 1;14:58. PubMed PMID: 25085119

Clemens JQ, Mullins C, Kusek JW, Kirkali Z, Mayer EA, Rodríguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Buchwald D, Andriole GL, Lucia MS, Landis JR, Clauw DJ, MAPP Research Network Study Group. Clemens J, Kirkali Z, Kusek JW, Landis J, Lucia M, Mullins C, Pontari MA, Klumpp DJ, Schaeffer AJ, Apkarian AV, Cella D, Farmer MA, Fitzgerald C, Gershon R, Griffith JW, Heckman CJ 2nd, Jiang M, Keefer L, Marko DS, Michniewicz J, Parrish T, Tu F, Mayer A, Rodríguez LV, Alger J, Ashe-McNalley CP, Ellingson B, Heendeniya N, Kilpatrick L, Kutch J, Labus JS, Naliboff BD, Randal F, Smith SR, Kreder KJ, Bradley CS, Eno M, Greiner K, Luo Y, Lutgendorf SK, O'Donnell MA, Ziegler B, Clauw DJ, Clemens J, As-Sanie S, Berry S, Halvorson ME, Harris R, Harte S, Ichesco E, Oldendorf A, Scott KA, Williams DA, Buchwald D, Afari N, Krieger J, Miller J, Richey S, Ross SO, Spiro R, Sundsvold TJ, Strachan E, Yang CC, Andriole GL, Lai H, Bristol RL, Colditz G, Deutsch G, Gardner VC, Gereau RW 4th, Henderson JP, Hong BA, Hooton TM, Ness TJ, North CS, Spitznagle TM, Sutcliffe S, Landis J, Barrell T, Hanno P, Hou X, Howard T, Pontari MA, Robinson N, Stephens A, Wang Y, Lucia M, van Bokhoven A, Osypuk AA, Dayton R Jr, Jonscher KR, Sullivan HT, Wilson R, Ehrlich GD, Moses MA, Briscoe AC, Briscoe D, Curatolo A, Froehlich J, Lee RS, Sachdev M, Solomon KR, Steen H, Mackey S, Bagarinao E, Foster LC, Hubbard E, Johnson KA, Martucci KT, McCue RL, Moericke RR, Nilakantan A, Noor N, Nickel J, Mullins C, Kusek JW, Kirkali Z, Bavendam TG.The MAPP research network: a novel study of urologic chronic pelvic pain syndromes. BMC Urol. 2014 Aug 1;14:57. PubMed PMID: 25085007

Lucia MS, van Bokhoven A. (2014) Biorepository Quality Assurance. In: Linda M. McManus, Richard N. Mitchell, editors. Pathobiology of Human Disease. San Diego: Elsevier; 2014. p. 3040-3045

van Bokhoven A (2014) Biorepository Operations and Infrastructure. In: Linda M. McManus, Richard N. Mitchell, editors. Pathobiology of Human Disease. San Diego: Elsevier; 2014. p. 3030-3034.

Lucia MS, van Bokhoven A, Infrastructure of the Biospecimen Repository and Associated Core Labs. Donna E. Hansel, Scott D. Jewell, Editors. Developing and Organizing an Institutional Biospecimen Repository. North Field: CAP Press: 2014. p. 23-32

Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Ehrlich GD. Assessment of the Lower Urinary Tract Microbiota during Symptom Flare in Women with Urologic Chronic Pelvic Pain Syndrome: A MAPP Network Study. J Urol. 2015 Sep 26. [Epub ahead of print] PubMed PMID: 26410734

Martin AM, Nirschl TR, Nirschl CJ, Francica BJ, Kochel CM, van Bokhoven A, Meeker AK, Lucia MS, Anders RA, DeMarzo AM, Drake CG. Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance. Prostate Cancer Prostatic Dis. 2015 Dec;18(4):325-32. PubMed PMID: 26260996

Hoque A, Yao S, Till C, Kristal AR, Goodman PJ, Hsing AW, Tangen CM, Platz EA, Stanczyk FZ, Reichardt JK, vanBokhoven A, Neuhouser ML, Santella RM, Figg WD, Price DK, Parnes HL, Lippman SM, Ambrosone CB, Thompson IM. Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease. Urology. 2015 Mar;85(3):616-20. PubMed PMID: 25733274

Nickel JC, Stephens A, Landis JR, Chen J, Mullins C, van Bokhoven A, Lucia MS, Melton-Kreft R, Ehrlich GD. Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network. J Urol. 2015 Jul;194(1):127-35. PubMed PMID: 25596358

Torkko KC, Wilson RS, Smith EE, Kusek JW, van Bokhoven A, Lucia MS. Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study. J Urol. 2015 Aug;194(2):454-61. PubMed PMID: 25828974

Krieger JN, Stephens AJ, Landis JR, Clemens JQ, Kreder K, Lai HH, Afari N, Rodríguez L, Schaeffer A, Mackey S, Andriole GL, Williams DA. Relationship between chronic nonurological associated somatic syndromes and symptom severity in urological chronic pelvic pain syndromes: baseline evaluation of the MAPP study. J Urol. 2015 Apr;193(4):1254-62. PubMed PMID: 25444992

Merrick DT, Edwards MG, Franklin WA, Sugita M, Miller Y, Friedman M, Dwyer-Nield L, Tennis M, Choo K, Hickey G, Kennedy T, van Bokhoven A, Heasley L, Hirsch FR, Bunn PA, Geraci M, Keith RL, Nemenoff R. Pathway Analysis of Gene Expression Profiles that Distinguish Persistent from Regressive Bronchial Dysplasia Indicate Synergistic Role for Polo-Like Kinase 1 (PLK1) and Epoxide Hydrolase 3 (EPHX3) in Malignant Progression. (ID 3334) 16th World Conference on Lung Cancer October September 6-9 2015, Denver, CO

Merrick DT, Donald EJ, Olson D, Okeefe MC, Edwards MG, Franklin WA, Dwyer-Nield L, Orlicky D, Keith RL, Miller YE, Tennis M, Barón AE, Lu Z, van Bokhoven A, Malinowski H, Bunn PA, Geraci MW, Nemenoff R. Role of Inflammatory Infiltrates in Promoting Persistence or Regression of Bronchial Dysplasia. 16th World Conference on Lung Cancer October September 6-9 2015, Denver, CO

Ostroff R, Mehan MR, Williams S, Niculescu-Mizil A, Franklin WA, Merrick DT, van Bokhoven A, Wolf H, Feser W, Baron A, Miller Y. Proteomic insights with lung cancer tumors based on histopathologic subtypes and genotypes. 16th World Conference on Lung Cancer October September 6-9 2015, Denver, CO

Torkko KC, Till C, Goodman PJ, Tangen CM, van Bokhoven A, Lucia MS, Thompson Jr.IM, Peters U, Neuhouser ML. Interactions between finasteride and vitamin D-related polymorphisms is associated with prostate cancer risk in African American men. Seventh AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; November 9-12, 2014; San Antonio, TX Cancer Epidemiol Biomarkers Prev 2015 24; B18

Merrick DT, Donald EJ, Olson D, O’Keefe MC, Edwards MG, Franklin WA, Dwyer-Nield L, Orlicky D, Keith RL, Miller YE, Tennis M, Baron A, Lu X, van Bokhoven A, Malinowski H, Bunn PA, Geraci M, Nemenoff R. Characterization of inflammatory infiltrates in persistent and regressive bronchial dysplasia (oral presentation), 2015 National Lung SPORE meeting.

Parker KS, Crowley JR, Stephens-Shields AJ, van Bokhoven A, Lucia MS, Lai HH, Andriole GL, Hooton TM, Mullins C, Henderson JP. Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort. EBioMedicine. 2016 May;7:167-74. PubMed PMID: 27322470

Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Ehrlich GD. Assessment of the Lower Urinary Tract Microbiota during Symptom Flare in Women with Urologic Chronic Pelvic Pain Syndrome: A MAPP Network Study. J Urol. 2016 Feb;195(2):356-62. PubMed PMID: 26410734

Stephens-Shields AJ, Clemens JQ, Jemielita T, Farrar J, Sutcliffe S, Hou X, Landis JR; MAPP Research Network. Clemens JQ, Hanno P, Kirkali Z, Kusek JW, Landis JR, Lucia MS, Moldwin RM, Mullins C, Pontari MA, Klumpp DJ, Schaeffer AJ, Apkarian AV, Cella D, Farmer MA, Fitzgerald C, Gershon R, Griffith JW, Heckman CJ 2nd, Jiang M, Keefer L, Marko DS, Michniewicz J, Parrish T, Tu F, Mayer EA, Rodríguez LV, Alger J, Ashe-McNalley CP, Ellingson B, Heendeniya N, Kilpatrick L, Kulbacki C, Kutch J, Labus JS, Naliboff BD, Randal F, Smith SR, Kreder KJ, Bradley CS, Eno M 2nd, Greiner K, Luo Y, Lutgendorf SK, O'Donnell MA, Ziegler B, Clauw DJ, Clemens JQ, As-Sanie S, Berry S, Halvorson ME, Harris R, Harte S, Ichesco E, Oldendorf A, Scott KA, Williams DA, Buchwald D, Afari N, Krieger J, Miller J, Richey S, Robertson K, Ross SO, Spiro R, Sundsvold TJ, Strachan E, Yang CC, Andriole GL, Lai HH, Bristol RL, Colditz G, Deutsch G, Gardner VC, Gereau RW 4th, Henderson JP, Hong BA, Hooton TM, Ness TJ, North CS, Spitznagle TM, Sutcliffe S, Anger J, Freeman M, Kim J, Eilber K, Van Eyk J, Yang W, Funari V, Cha J, Richard Landis J, Barrell T, Hanno P, Doe RP, Farrar JT, Gallagher L, Hou X, Jemielita T, Howard T, Pontari MA, Robinson N, Smith S, Stephens A, Wang Y, Wang X, Lucia MS, van Bokhoven A, Osypuk AA, Dayton R Jr, Jonscher KR, Sullivan HT, Wilson RS, Moses MA, Briscoe AC, Briscoe D, Curatolo A, Froehlich J, Lee RS, Sachdev M, Solomon KR, Steen H, Mackey S, Bagarinao E, Foster LC, Hubbard E, Johnson KA, Martucci KT, McCue RL, Moericke RR, Nilakantan A, Noor N, Nickel JC, Ehrlich GD, Mullins C, Kusek JW, Kirkali Z, Bavendam TG.. Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome. J Urol. 2016 Nov;196(5):1450-1455. PubMed PMID: 27131464

Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA. A Case-Crossover Study of Urologic Chronic Pelvic Pain Syndrome Flare Triggers in the Mapp Research Network. J Urol. 2017 Dec 27. [Epub ahead of print] PubMed PMID: 29288643

Werahera PN, Jasion EA, Crawford ED, Lucia MS, van Bokhoven A, Sullivan HT, Kim FJ, Maroni PD, Port JD, Daily JW, La Rosa FG. Diffuse Reflectance Can Differentiate High Grade and Low Grade Prostatic Carcinoma. Conf Proc IEEE Eng Med Biol Soc. pp 5148-5151, 2016.

Flaig TW, Salzmann-Sullivan M, Su LJ, Zhang Z, Joshi M, Gijón MA, Kim J, Arcaroli JJ, Van Bokhoven A, Lucia MS, La Rosa FG, Schlaepfer IR. Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade. Oncotarget. 2017 Aug 22;8(34):56051-56065. PubMed PMID: 28915573

Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua A, Crawford ED. The 4Kscore Can Potentially Reduce Unnecessary Prostate Biopsies in Men with Suspicious PSA in a Screening Population, J Urol 195(4S):e543, 2016. Presented at the American Urological Association (AUA) Meeting, San Diego, CA May 6-10, 2016

Dagher A, Curatolo A, Sachdev M, Stephens AJ, Mullins C, Landis JR, van Bokhoven A, El-Hayek A, Froehlich JW, Briscoe AC, Roy R, Yang J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Identification of novel non-invasive biomarkers of urinary chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. BJU Int. 2017 Jul;120(1):130-142. PubMed PMID: 28263447

Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua A, Crawford ED. Does Digital Rectal Exam Affect The 4Kscore Test for Aggressive Prostate Cancer? J Urol 195(4S):e646, 2016. Presented at the American Urological Association (AUA) Meeting, San Diego, CA May 6-10, 2016

Werahera PN, Jasion EA, Crawford ED, Lucia MS, van Bokhoven A, Daily JW, Fernando FJ, La Rosa, FG. Diagnostic Accuracy of Prostate Biopsies can be Improved by Optical Characterization of Prostate Tissue. 95th Annual Meeting of the South Central Section of the AUA, Colorado Springs, CO, September 28 to October 1, 2016

Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua A, Crawford ED. Does Digital Rectal Exam Affect The 4Kscore Test for Aggressive Prostate Cancer? 95th Annual Meeting of the South Central Section of the AUA, Colorado Springs, CO, September 28 to October 1, 2016

Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua P, Crawford ED. The 4Kscore Can Potentially Reduce Unnecessary Prostate Biopsies in Men with Suspicious PSA in a Screening Population. 95th Annual Meeting of the South Central Section of the AUA, Colorado Springs, CO, September 28 to October 1, 2016.

Clemens JQ, Mullins C, Ackerman AL, Bavendam T, van Bokhoven A, Ellingson BM, Harte SE, Kutch JJ, Lai HH, Martucci KT, Moldwin R, Naliboff BD, Pontari MA, Sutcliffe S, Landis JR. Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network. Nat Rev Urol. 2018 Dec 18. [Epub ahead of print] PubMed PMID: 30560936

Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2019 Jan;20(1):e39-e51. PubMed PMID: 30297175

Lucia MS, van Bokhoven A. Requisite for Collection and Distribution of Tissue and Fluid Specimens in Molecular Diagnostics. In: Precision Molecular Pathology of Bladder Cancer, Hansel D.E. and Lerner S.P., eds. Springer International

Yu H, Chen Z, Ballman KV, Watson MA, Govindan R, Lanc I, Beer DG, Bueno R, Chirieac LR, Chui MH, Chen G, Franklin WA, Gandara DR, Genova C, Brovsky KA, Joshi MM, Merrick DT, Richards WG, Rivard CJ, Harpole DH, Tsao MS, van Bokhoven A, Shepherd FA, Hirsch FR. Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. J Thorac Oncol. 2019 Jan;14(1):25-36. PubMed PMID: 30253973

Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, Dickey BF, Velmurugan K, Mann PR, Lu X, Barón AE, Evans CM, Moghaddam SJ. Requirement for MUC5AC in KRAS-dependent lung carcinogenesis. JCI Insight. 2018 Aug 9;3(15). [Epub ahead of print] PubMed PMID: 30089720

Diamond JR, Eckhardt SG, Pitts TM, van Bokhoven A, Aisner D, Gustafson DL, Capasso A, Sams S, Kabos P, Zolman K, Colvin T, Elias AD, Storniolo AM, Schneider BP, Gao D, Tentler JJ, Borges VF, Miller KD. A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer. Breast Cancer Res. 2018 Aug 2;20(1):82. PubMed PMID: 30071865

Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA. Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia. Cancer Res. 2018 Sep 1;78(17):4971-4983. PubMed PMID: 29997230

Maccini MA, Westfall NJ, Van Bokhoven A, Lucia MS, Poage W, Maroni PD, Wilson SS, Glodé LM, Arangua P, Newmark J, Steiner M, Werahera PN, Crawford ED. The effect of digital rectal exam on the 4Kscore for aggressive prostate cancer. Prostate. 2018 May;78(7):506-511. PubMed PMID: 29460452

Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA. A Case-Crossover Study of Urological Chronic Pelvic Pain Syndrome Flare Triggers in the MAPP Research Network. J Urol. 2018 May;199(5):1245-1251. PubMed PMID: 29288643

Panigrahi GK, Praharaj PP, Kittaka H, Mridha AR, Black OM, Singh R, Mercer R, van Bokhoven A, Torkko KC, Agarwal C, Agarwal R, Abd Elmageed ZY, Yadav H, Mishra SK, Deep G. Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients. Cancer Med. 2019 Jan 8. [Epub ahead of print] PubMed PMID: 30623593

Ihle CL, Provera MD, Straign DM, Smith EE, Edgerton SM, Van Bokhoven A, Lucia MS, Owens P. Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients. J Immunother Cancer. 2019 Nov 8;7(1):293. PubMed PMID: 31703602

Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Anger JT, Ackerman AL, Kim J, Sutcliffe S, Krol JE, Sen B, Hammond J, Ehrlich GD. Urinary fungi associated with urinary symptom severity among women with interstitial cystitis/bladder pain syndrome (IC/BPS). World J Urol. 2019 Apr 26. [Epub ahead of print] PubMed PMID: 31028455

Nickel JC, Stephens-Shields AJ, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Henderson JP, Sen B, Krol JE, Ehrlich GD. A Culture-Independent Analysis of the Microbiota of Female Interstitial Cystitis/Bladder Pain Syndrome Participants in the MAPP Research Network. J Clin Med. 2019 Mar 26;8(3). PubMed PMID: 30917614

Panigrahi GK, Praharaj PP, Kittaka H, Mridha AR, Black OM, Singh R, Mercer R, van Bokhoven A, Torkko KC, Agarwal C, Agarwal R, Abd Elmageed ZY, Yadav H, Mishra SK, Deep G. Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients. Cancer Med. 2019 Mar;8(3):1110-1123. PubMed PMID: 30623593

Clemens JQ, Mullins C, Ackerman AL, Bavendam T, van Bokhoven A, Ellingson BM, Harte SE, Kutch JJ, Lai HH, Martucci KT, Moldwin R, Naliboff BD, Pontari MA, Sutcliffe S, Landis JR. Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network. Nat Rev Urol. 2019 Mar;16(3):187-200. PubMed PMID: 30560936

Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2019 Jan;20(1):e39-e51. PubMed PMID: 30297175

Ng TL, Johnson A, Nemenoff RA, Hsieh E, Osypuk AA, van Bokhoven A, Li H, Camidge DR, Schenk EL. Prospective Observational Study Revealing Early Pulmonary Function Changes Associated With Brigatinib Initiation. J Thorac Oncol. 2020 Dec 9. [Epub ahead of print] PubMed PMID: 33307191

Yu H, Chen Z, Ballman KV, Watson MA, Govindan R, Lanc I, Beer DG, Bueno R, Chirieac LR, Chui MH, Chen G, Franklin WA, Gandara DR, Genova C, Brovsky KA, Joshi MM, Merrick DT, Richards WG, Rivard CJ, Harpole DH, Tsao MS, van Bokhoven A, Shepherd FA, Hirsch FR. Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. J Thorac Oncol. 2019 Jan;14(1):25-36. PubMed PMID: 30253973

Roy R, Stephens AJ, Daisy C, Merritt L, Newcomb CW, Yang J, Dagher A, Curatolo A, Sachdev M, McNeish B, Landis R, van Bokhoven A, El-Hayek A, Froehlich J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Association of Longitudinal Changes in Symptoms and Urinary Biomarkers in Patients with Urological Chronic Pelvic Pain Syndrome: A MAPP Research Network Study. J Urol. 2021 Feb;205(2):514-523. PubMed PMID: 33026902

Bueno R, Richards WG, Harpole DH, Ballman KV, Tsao MS, Chen Z, Wang X, Chen G, Chirieac LR, Chui MH, Franklin WA, Giordano TJ, Govindan R, Joshi MB, Merrick DT, Rivard CJ, Sporn T, van Bokhoven A, Yu H, Shepherd FA, Watson MA, Beer DG, Hirsch FR. Multi-Institutional Prospective Validation of Prognostic mRNA Signatures in Early Stage Squamous Lung Cancer (Alliance). J Thorac Oncol. 2020 Nov;15(11):1748-1757. PubMed PMID: 32717408

Clemens JQ, Kutch JJ, Mayer EA, Naliboff BD, Rodriguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Clauw DJ, Harte SE, Schrepf AD, Williams DA, Andriole GL, Lai HH, Buchwald D, Lucia MS, van Bokhoven A, Mackey S, Moldwin RM, Pontari MA, Stephens-Shields AJ, Mullins C, Landis JR. The Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS). Neurourol Urodyn. 2020 Aug;39(6):1803-1814. PubMed PMID: 32578257

Robles MTS, Cantalupo PG, Duray AM, Freeland M, Murkowski M, van Bokhoven A, Stephens-Shields AJ, Pipas JM, Imperiale MJ. Analysis of viruses present in urine from patients with interstitial cystitis. Virus Genes. 2020 Aug;56(4):430-438. PubMed PMID: 32447589

Torkko K, Till C, Tangen CM, Goodman PJ, Song X, Schenk JM, Lucia MS, Peters U, van Bokhoven A, Thompson IM, Neuhouser ML. Vitamin D Pathway and Other Related Polymorphisms and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial. Cancer Prev Res (Phila). 2020 Jun;13(6):521-530. PubMed PMID: 32102946

Stanton WN, Crawford ED, Arangua PB, La Rosa FG, van Bokhoven A, Lucia MS, Poage WL, Partin A, Maroni P, Werahera PN. Assessment of high-grade prostate cancer risk using prostate cancer biomarkers. Can J Urol. 2020 Feb;27(1):10080-10085. PubMed PMID: 32065862

Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Anger JT, Ackerman AL, Kim J, Sutcliffe S, Krol JE, Sen B, Hammond J, Ehrlich GD. Urinary fungi associated with urinary symptom severity among women with interstitial cystitis/bladder pain syndrome (IC/BPS). World J Urol. 2020 Feb;38(2):433-446. PubMed PMID: 31028455

Froehlich JW, Scott Wang HH, Logvinenko T, Kostel S, DiMartino S, van Bokhoven A, Moses MA, Lee RS. "The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study". Mol Cell Proteomics. 2021 Nov 10;:100176. [Epub ahead of print] PubMed PMID: 34774759

Nordeen SK, Su LJ, Osborne GA, Hayman PM, Orlicky DJ, Wessells VM, van Bokhoven A, Flaig TW. Titration of Androgen Signaling: How Basic Studies Have Informed Clinical Trials Using High-Dose Testosterone Therapy in Castrate-Resistant Prostate Cancer. Life (Basel). 2021 Aug 27;11(9). PubMed PMID: 34575033

Borgers JSW, Tobin RP, Torphy RJ, Vorwald VM, Van Gulick RJ, Amato CM, Cogswell DT, Chimed TS, Couts KL, Van Bokhoven A, Raeburn CD, Lewis KD, Wisell J, McCarter MD, Mushtaq RR, Robinson WA. Melanoma Metastases to the Adrenal Gland Are Highly Resistant to Immune Checkpoint Inhibitors. J Natl Compr Canc Netw. 2021 Aug 4. [Epub ahead of print] PubMed PMID: 34348236

Gurule NJ, McCoach CE, Hinz TK, Merrick DT, Van Bokhoven A, Kim J, Patil T, Calhoun J, Nemenoff RA, Tan AC, Doebele RC, Heasley LE. A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer. NPJ Precis Oncol. 2021 May 17;5(1):41. PubMed PMID: 34001994

Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Chiaro MD, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Neto AG, Lagares D, Hansen KC, Van Bokhoven A, Karam SD. Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer. Cancer Res. 2021 Jun 15;81(12):3255-3269. PubMed PMID: 33526513

Ng TL, Johnson A, Nemenoff RA, Hsieh E, Osypuk AA, van Bokhoven A, Li H, Camidge DR, Schenk EL. Prospective Observational Study Revealing Early Pulmonary Function Changes Associated With Brigatinib Initiation. J Thorac Oncol. 2021 Mar;16(3):486-491. PubMed PMID: 33307191

Roy R, Stephens AJ, Daisy C, Merritt L, Newcomb CW, Yang J, Dagher A, Curatolo A, Sachdev M, McNeish B, Landis R, van Bokhoven A, El-Hayek A, Froehlich J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Association of Longitudinal Changes in Symptoms and Urinary Biomarkers in Patients with Urological Chronic Pelvic Pain Syndrome: A MAPP Research Network Study. J Urol. 2021 Feb;205(2):514-523. PubMed PMID: 33026902

Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC. Nat Cancer. 2022 Nov;3(11):1300-1317. PubMed PMID: 36434392

Schrepf A, Kaplan C, Harris RE, Williams DA, Clauw DJ, As-Sanie S, Till S, Clemens JQ, Rodriguez LV, Van Bokhoven A, Landis R, Gallop R, Bradley C, Naliboff B, Pontari M, O'Donnell M, Luo Y, Kreder K, Lutgendorf SK, Harte SE. Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study. Pain. 2022 Oct 19. [Epub ahead of print] PubMed PMID: 36279178

Froehlich JW, Wang HS, Logvinenko T, Kostel S, DiMartino S, van Bokhoven A, Moses MA, Lee RS. The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study. Mol Cell Proteomics. 2022 Jan;21(1):100176. PubMed PMID: 34774759

Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 Jun 30;8(84):eade5343. PubMed PMID: 37390222

Elias AD, Spoelstra NS, Staley AW, Sams S, Crump LS, Vidal GA, Borges VF, Kabos P, Diamond JR, Shagisultanova E, Afghahi A, Mayordomo J, McSpadden T, Crawford G, D'Alessandro A, Zolman KL, van Bokhoven A, Zhuang Y, Gallagher RI, Wulfkuhle JD, Petricoin Iii EF, Gao D, Richer JK. Phase II trial of fulvestrant plus enzalutamide in ER /HER2- advanced breast cancer. NPJ Breast Cancer. 2023 May 20;9(1):41. PubMed PMID: 37210417

Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD, Quentin Clemens J, Kreder KJ, Schrepf A. Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study. Brain Behav Immun. 2023 Jul;111:116-123. PubMed PMID: 37001828

Schrepf A, Kaplan C, Harris RE, Williams DA, Clauw DJ, As-Sanie S, Till S, Clemens JQ, Rodriguez LV, Van Bokhoven A, Landis R, Gallop R, Bradley C, Naliboff B, Pontari M, O'Donnell M, Luo Y, Kreder K, Lutgendorf SK, Harte SE. Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study. Pain. 2023 May 1;164(5):1148-1157. PubMed PMID: 36279178

Associate Professor, Pathology

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School of Medicine

CU Anschutz

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