Adriaan Van Bokhoven, PhD

Publications

• Darragh LB, Nguyen A, Pham TT, Idlett-Ali S, Knitz MW, Gadwa J, Bukkapatnam S, Corbo S, Olimpo NA, Nguyen D, Van Court B, Neupert B, Yu J, Ross RB, Corbisiero M, Abdelazeem KNM, Maroney SP, Galindo DC, Mukdad L, Saviola A, Joshi M, White R, Alhiyari Y, Samedi V, Van Bokhoven A, St John M, Karam SD. Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs. Med. 2024 Mar 8;5(3):254-270.e8. PubMed PMID: 38423011
• Baxter RM, Cabrera-Martinez B, Ghosh T, Rester C, Moreno MG, Borko TL, Selva S, Fleischer CL, Haakonsen N, Mayher A, Bowhay E, Evans C, Miller TM, Huey L, McWilliams J, van Bokhoven A, Deane KD, Knight V, Jordan KR, Ghosh D, Klarquist J, Kedl RM, Piquet AL, Hsieh EWY. SARS-CoV-2 Vaccine-Elicited Immunity after B Cell Depletion in Multiple Sclerosis. Immunohorizons. 2024 Mar 1;8(3):254-268. PubMed PMID: 38483384
• Purdue MP, Dutta D, Machiela MJ, Gorman BR, Winter T, Okuhara D, Cleland S, Ferreiro-Iglesias A, Scheet P, Liu A, Wu C, Antwi SO, Larkin J, Zequi SC, Sun M, Hikino K, Hajiran A, Lawson KA, Cárcano F, Blanchet O, Shuch B, Nepple KG, Margue G, Sundi D, Diver WR, Folgueira MAAK, van Bokhoven A, Neffa F, Brown KM, Hofmann JN, Rhee J, Yeager M, Cole NR, Hicks BD, Manning MR, Hutchinson AA, Rothman N, Huang WY, Linehan WM, Lori A, Ferragu M, Zidane-Marinnes M, Serrano SV, Magnabosco WJ, Vilas A, Decia R, Carusso F, Graham LS, Anderson K, Bilen MA, Arciero C, Pellegrin I, Ricard S, Scelo G, Banks RE, Vasudev NS, Soomro N, Stewart GD, Adeyoju A, Bromage S, Hrouda D, Gibbons N, Patel P, Sullivan M, Protheroe A, Nugent FI, Fournier MJ, Zhang X, Martin LJ, Komisarenko M, Eisen T, Cunningham SA, Connolly DC, Uzzo RG, Zaridze D, Mukeria A, Holcatova I, Hornakova A, Foretova L, Janout V, Mates D, Jinga V, Rascu S, Mijuskovic M, Savic S, Milosavljevic S, Gaborieau V, Abedi-Ardekani B, McKay J, Johansson M, Phouthavongsy L, Hayman L, Li J, Lungu I, Bezerra SM, Souza AG, Sares CTG, Reis RB, Gallucci FP, Cordeiro MD, Pomerantz M, Lee GM, Freedman ML, Jeong A, Greenberg SE, Sanchez A, Thompson RH, Sharma V, Thiel DD, Ball CT, Abreu D, Lam ET, Nahas WC, Master VA, Patel AV, Bernhard JC, Freedman ND, Bigot P, Reis RM, Colli LM, Finelli A, Manley BJ, Terao C, Choueiri TK, Carraro DM, Houlston R, Eckel-Passow JE, Abbosh PH, Ganna A, Brennan P, Gu J, Chanock SJ. Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nat Genet. 2024 May;56(5):809-818. PubMed PMID: 38671320
• Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 Jun 30;8(84):eade5343. PubMed PMID: 37390222
• Elias AD, Spoelstra NS, Staley AW, Sams S, Crump LS, Vidal GA, Borges VF, Kabos P, Diamond JR, Shagisultanova E, Afghahi A, Mayordomo J, McSpadden T, Crawford G, D'Alessandro A, Zolman KL, van Bokhoven A, Zhuang Y, Gallagher RI, Wulfkuhle JD, Petricoin Iii EF, Gao D, Richer JK. Phase II trial of fulvestrant plus enzalutamide in ER /HER2- advanced breast cancer. NPJ Breast Cancer. 2023 May 20;9(1):41. PubMed PMID: 37210417
• Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD, Quentin Clemens J, Kreder KJ, Schrepf A. Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study. Brain Behav Immun. 2023 Jul;111:116-123. PubMed PMID: 37001828
• Schrepf A, Kaplan C, Harris RE, Williams DA, Clauw DJ, As-Sanie S, Till S, Clemens JQ, Rodriguez LV, Van Bokhoven A, Landis R, Gallop R, Bradley C, Naliboff B, Pontari M, O'Donnell M, Luo Y, Kreder K, Lutgendorf SK, Harte SE. Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study. Pain. 2023 May 1;164(5):1148-1157. PubMed PMID: 36279178
• Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC. Nat Cancer. 2022 Nov;3(11):1300-1317. PubMed PMID: 36434392
• Schrepf A, Kaplan C, Harris RE, Williams DA, Clauw DJ, As-Sanie S, Till S, Clemens JQ, Rodriguez LV, Van Bokhoven A, Landis R, Gallop R, Bradley C, Naliboff B, Pontari M, O'Donnell M, Luo Y, Kreder K, Lutgendorf SK, Harte SE. Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study. Pain. 2022 Oct 19. [Epub ahead of print] PubMed PMID: 36279178
• Froehlich JW, Wang HS, Logvinenko T, Kostel S, DiMartino S, van Bokhoven A, Moses MA, Lee RS. The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study. Mol Cell Proteomics. 2022 Jan;21(1):100176. PubMed PMID: 34774759
• Roy R, Stephens AJ, Daisy C, Merritt L, Newcomb CW, Yang J, Dagher A, Curatolo A, Sachdev M, McNeish B, Landis R, van Bokhoven A, El-Hayek A, Froehlich J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Association of Longitudinal Changes in Symptoms and Urinary Biomarkers in Patients with Urological Chronic Pelvic Pain Syndrome: A MAPP Research Network Study. J Urol. 2021 Feb;205(2):514-523. PubMed PMID: 33026902
• Froehlich JW, Scott Wang HH, Logvinenko T, Kostel S, DiMartino S, van Bokhoven A, Moses MA, Lee RS. "The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study". Mol Cell Proteomics. 2021 Nov 10;:100176. [Epub ahead of print] PubMed PMID: 34774759
• Nordeen SK, Su LJ, Osborne GA, Hayman PM, Orlicky DJ, Wessells VM, van Bokhoven A, Flaig TW. Titration of Androgen Signaling: How Basic Studies Have Informed Clinical Trials Using High-Dose Testosterone Therapy in Castrate-Resistant Prostate Cancer. Life (Basel). 2021 Aug 27;11(9). PubMed PMID: 34575033
• Borgers JSW, Tobin RP, Torphy RJ, Vorwald VM, Van Gulick RJ, Amato CM, Cogswell DT, Chimed TS, Couts KL, Van Bokhoven A, Raeburn CD, Lewis KD, Wisell J, McCarter MD, Mushtaq RR, Robinson WA. Melanoma Metastases to the Adrenal Gland Are Highly Resistant to Immune Checkpoint Inhibitors. J Natl Compr Canc Netw. 2021 Aug 4. [Epub ahead of print] PubMed PMID: 34348236
• Gurule NJ, McCoach CE, Hinz TK, Merrick DT, Van Bokhoven A, Kim J, Patil T, Calhoun J, Nemenoff RA, Tan AC, Doebele RC, Heasley LE. A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer. NPJ Precis Oncol. 2021 May 17;5(1):41. PubMed PMID: 34001994
• Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Chiaro MD, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Neto AG, Lagares D, Hansen KC, Van Bokhoven A, Karam SD. Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer. Cancer Res. 2021 Jun 15;81(12):3255-3269. PubMed PMID: 33526513
• Ng TL, Johnson A, Nemenoff RA, Hsieh E, Osypuk AA, van Bokhoven A, Li H, Camidge DR, Schenk EL. Prospective Observational Study Revealing Early Pulmonary Function Changes Associated With Brigatinib Initiation. J Thorac Oncol. 2021 Mar;16(3):486-491. PubMed PMID: 33307191
• Roy R, Stephens AJ, Daisy C, Merritt L, Newcomb CW, Yang J, Dagher A, Curatolo A, Sachdev M, McNeish B, Landis R, van Bokhoven A, El-Hayek A, Froehlich J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Association of Longitudinal Changes in Symptoms and Urinary Biomarkers in Patients with Urological Chronic Pelvic Pain Syndrome: A MAPP Research Network Study. J Urol. 2021 Feb;205(2):514-523. PubMed PMID: 33026902
• Bueno R, Richards WG, Harpole DH, Ballman KV, Tsao MS, Chen Z, Wang X, Chen G, Chirieac LR, Chui MH, Franklin WA, Giordano TJ, Govindan R, Joshi MB, Merrick DT, Rivard CJ, Sporn T, van Bokhoven A, Yu H, Shepherd FA, Watson MA, Beer DG, Hirsch FR. Multi-Institutional Prospective Validation of Prognostic mRNA Signatures in Early Stage Squamous Lung Cancer (Alliance). J Thorac Oncol. 2020 Nov;15(11):1748-1757. PubMed PMID: 32717408
• Clemens JQ, Kutch JJ, Mayer EA, Naliboff BD, Rodriguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Clauw DJ, Harte SE, Schrepf AD, Williams DA, Andriole GL, Lai HH, Buchwald D, Lucia MS, van Bokhoven A, Mackey S, Moldwin RM, Pontari MA, Stephens-Shields AJ, Mullins C, Landis JR. The Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS). Neurourol Urodyn. 2020 Aug;39(6):1803-1814. PubMed PMID: 32578257
• Robles MTS, Cantalupo PG, Duray AM, Freeland M, Murkowski M, van Bokhoven A, Stephens-Shields AJ, Pipas JM, Imperiale MJ. Analysis of viruses present in urine from patients with interstitial cystitis. Virus Genes. 2020 Aug;56(4):430-438. PubMed PMID: 32447589
• Torkko K, Till C, Tangen CM, Goodman PJ, Song X, Schenk JM, Lucia MS, Peters U, van Bokhoven A, Thompson IM, Neuhouser ML. Vitamin D Pathway and Other Related Polymorphisms and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial. Cancer Prev Res (Phila). 2020 Jun;13(6):521-530. PubMed PMID: 32102946
• Stanton WN, Crawford ED, Arangua PB, La Rosa FG, van Bokhoven A, Lucia MS, Poage WL, Partin A, Maroni P, Werahera PN. Assessment of high-grade prostate cancer risk using prostate cancer biomarkers. Can J Urol. 2020 Feb;27(1):10080-10085. PubMed PMID: 32065862
• Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Anger JT, Ackerman AL, Kim J, Sutcliffe S, Krol JE, Sen B, Hammond J, Ehrlich GD. Urinary fungi associated with urinary symptom severity among women with interstitial cystitis/bladder pain syndrome (IC/BPS). World J Urol. 2020 Feb;38(2):433-446. PubMed PMID: 31028455
• Ng TL, Johnson A, Nemenoff RA, Hsieh E, Osypuk AA, van Bokhoven A, Li H, Camidge DR, Schenk EL. Prospective Observational Study Revealing Early Pulmonary Function Changes Associated With Brigatinib Initiation. J Thorac Oncol. 2020 Dec 9. [Epub ahead of print] PubMed PMID: 33307191
• Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2019 Jan;20(1):e39-e51. PubMed PMID: 30297175
• Yu H, Chen Z, Ballman KV, Watson MA, Govindan R, Lanc I, Beer DG, Bueno R, Chirieac LR, Chui MH, Chen G, Franklin WA, Gandara DR, Genova C, Brovsky KA, Joshi MM, Merrick DT, Richards WG, Rivard CJ, Harpole DH, Tsao MS, van Bokhoven A, Shepherd FA, Hirsch FR. Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. J Thorac Oncol. 2019 Jan;14(1):25-36. PubMed PMID: 30253973
• Panigrahi GK, Praharaj PP, Kittaka H, Mridha AR, Black OM, Singh R, Mercer R, van Bokhoven A, Torkko KC, Agarwal C, Agarwal R, Abd Elmageed ZY, Yadav H, Mishra SK, Deep G. Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients. Cancer Med. 2019 Jan 8. [Epub ahead of print] PubMed PMID: 30623593
• Ihle CL, Provera MD, Straign DM, Smith EE, Edgerton SM, Van Bokhoven A, Lucia MS, Owens P. Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients. J Immunother Cancer. 2019 Nov 8;7(1):293. PubMed PMID: 31703602
• Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Anger JT, Ackerman AL, Kim J, Sutcliffe S, Krol JE, Sen B, Hammond J, Ehrlich GD. Urinary fungi associated with urinary symptom severity among women with interstitial cystitis/bladder pain syndrome (IC/BPS). World J Urol. 2019 Apr 26. [Epub ahead of print] PubMed PMID: 31028455
• Nickel JC, Stephens-Shields AJ, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Henderson JP, Sen B, Krol JE, Ehrlich GD. A Culture-Independent Analysis of the Microbiota of Female Interstitial Cystitis/Bladder Pain Syndrome Participants in the MAPP Research Network. J Clin Med. 2019 Mar 26;8(3). PubMed PMID: 30917614
• Panigrahi GK, Praharaj PP, Kittaka H, Mridha AR, Black OM, Singh R, Mercer R, van Bokhoven A, Torkko KC, Agarwal C, Agarwal R, Abd Elmageed ZY, Yadav H, Mishra SK, Deep G. Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients. Cancer Med. 2019 Mar;8(3):1110-1123. PubMed PMID: 30623593
• Clemens JQ, Mullins C, Ackerman AL, Bavendam T, van Bokhoven A, Ellingson BM, Harte SE, Kutch JJ, Lai HH, Martucci KT, Moldwin R, Naliboff BD, Pontari MA, Sutcliffe S, Landis JR. Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network. Nat Rev Urol. 2019 Mar;16(3):187-200. PubMed PMID: 30560936
• Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2019 Jan;20(1):e39-e51. PubMed PMID: 30297175
• Yu H, Chen Z, Ballman KV, Watson MA, Govindan R, Lanc I, Beer DG, Bueno R, Chirieac LR, Chui MH, Chen G, Franklin WA, Gandara DR, Genova C, Brovsky KA, Joshi MM, Merrick DT, Richards WG, Rivard CJ, Harpole DH, Tsao MS, van Bokhoven A, Shepherd FA, Hirsch FR. Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. J Thorac Oncol. 2019 Jan;14(1):25-36. PubMed PMID: 30253973
• Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, Dickey BF, Velmurugan K, Mann PR, Lu X, Barón AE, Evans CM, Moghaddam SJ. Requirement for MUC5AC in KRAS-dependent lung carcinogenesis. JCI Insight. 2018 Aug 9;3(15). [Epub ahead of print] PubMed PMID: 30089720
• Diamond JR, Eckhardt SG, Pitts TM, van Bokhoven A, Aisner D, Gustafson DL, Capasso A, Sams S, Kabos P, Zolman K, Colvin T, Elias AD, Storniolo AM, Schneider BP, Gao D, Tentler JJ, Borges VF, Miller KD. A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer. Breast Cancer Res. 2018 Aug 2;20(1):82. PubMed PMID: 30071865
• Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA. Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia. Cancer Res. 2018 Sep 1;78(17):4971-4983. PubMed PMID: 29997230
• Maccini MA, Westfall NJ, Van Bokhoven A, Lucia MS, Poage W, Maroni PD, Wilson SS, Glodé LM, Arangua P, Newmark J, Steiner M, Werahera PN, Crawford ED. The effect of digital rectal exam on the 4Kscore for aggressive prostate cancer. Prostate. 2018 May;78(7):506-511. PubMed PMID: 29460452
• Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA. A Case-Crossover Study of Urological Chronic Pelvic Pain Syndrome Flare Triggers in the MAPP Research Network. J Urol. 2018 May;199(5):1245-1251. PubMed PMID: 29288643
• Clemens JQ, Mullins C, Ackerman AL, Bavendam T, van Bokhoven A, Ellingson BM, Harte SE, Kutch JJ, Lai HH, Martucci KT, Moldwin R, Naliboff BD, Pontari MA, Sutcliffe S, Landis JR. Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network. Nat Rev Urol. 2018 Dec 18. [Epub ahead of print] PubMed PMID: 30560936
• Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA. A Case-Crossover Study of Urologic Chronic Pelvic Pain Syndrome Flare Triggers in the Mapp Research Network. J Urol. 2017 Dec 27. [Epub ahead of print] PubMed PMID: 29288643
• Flaig TW, Salzmann-Sullivan M, Su LJ, Zhang Z, Joshi M, Gijón MA, Kim J, Arcaroli JJ, Van Bokhoven A, Lucia MS, La Rosa FG, Schlaepfer IR. Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade. Oncotarget. 2017 Aug 22;8(34):56051-56065. PubMed PMID: 28915573
• Dagher A, Curatolo A, Sachdev M, Stephens AJ, Mullins C, Landis JR, van Bokhoven A, El-Hayek A, Froehlich JW, Briscoe AC, Roy R, Yang J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Identification of novel non-invasive biomarkers of urinary chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. BJU Int. 2017 Jul;120(1):130-142. PubMed PMID: 28263447
• Parker KS, Crowley JR, Stephens-Shields AJ, van Bokhoven A, Lucia MS, Lai HH, Andriole GL, Hooton TM, Mullins C, Henderson JP. Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort. EBioMedicine. 2016 May;7:167-74. PubMed PMID: 27322470
• Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Ehrlich GD. Assessment of the Lower Urinary Tract Microbiota during Symptom Flare in Women with Urologic Chronic Pelvic Pain Syndrome: A MAPP Network Study. J Urol. 2016 Feb;195(2):356-62. PubMed PMID: 26410734
• Stephens-Shields AJ, Clemens JQ, Jemielita T, Farrar J, Sutcliffe S, Hou X, Landis JR; MAPP Research Network. Clemens JQ, Hanno P, Kirkali Z, Kusek JW, Landis JR, Lucia MS, Moldwin RM, Mullins C, Pontari MA, Klumpp DJ, Schaeffer AJ, Apkarian AV, Cella D, Farmer MA, Fitzgerald C, Gershon R, Griffith JW, Heckman CJ 2nd, Jiang M, Keefer L, Marko DS, Michniewicz J, Parrish T, Tu F, Mayer EA, Rodríguez LV, Alger J, Ashe-McNalley CP, Ellingson B, Heendeniya N, Kilpatrick L, Kulbacki C, Kutch J, Labus JS, Naliboff BD, Randal F, Smith SR, Kreder KJ, Bradley CS, Eno M 2nd, Greiner K, Luo Y, Lutgendorf SK, O'Donnell MA, Ziegler B, Clauw DJ, Clemens JQ, As-Sanie S, Berry S, Halvorson ME, Harris R, Harte S, Ichesco E, Oldendorf A, Scott KA, Williams DA, Buchwald D, Afari N, Krieger J, Miller J, Richey S, Robertson K, Ross SO, Spiro R, Sundsvold TJ, Strachan E, Yang CC, Andriole GL, Lai HH, Bristol RL, Colditz G, Deutsch G, Gardner VC, Gereau RW 4th, Henderson JP, Hong BA, Hooton TM, Ness TJ, North CS, Spitznagle TM, Sutcliffe S, Anger J, Freeman M, Kim J, Eilber K, Van Eyk J, Yang W, Funari V, Cha J, Richard Landis J, Barrell T, Hanno P, Doe RP, Farrar JT, Gallagher L, Hou X, Jemielita T, Howard T, Pontari MA, Robinson N, Smith S, Stephens A, Wang Y, Wang X, Lucia MS, van Bokhoven A, Osypuk AA, Dayton R Jr, Jonscher KR, Sullivan HT, Wilson RS, Moses MA, Briscoe AC, Briscoe D, Curatolo A, Froehlich J, Lee RS, Sachdev M, Solomon KR, Steen H, Mackey S, Bagarinao E, Foster LC, Hubbard E, Johnson KA, Martucci KT, McCue RL, Moericke RR, Nilakantan A, Noor N, Nickel JC, Ehrlich GD, Mullins C, Kusek JW, Kirkali Z, Bavendam TG.. Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome. J Urol. 2016 Nov;196(5):1450-1455. PubMed PMID: 27131464
• Werahera PN, Jasion EA, Crawford ED, Lucia MS, van Bokhoven A, Sullivan HT, Kim FJ, Maroni PD, Port JD, Daily JW, La Rosa FG. Diffuse Reflectance Can Differentiate High Grade and Low Grade Prostatic Carcinoma. Conf Proc IEEE Eng Med Biol Soc. pp 5148-5151, 2016.
• Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua A, Crawford ED. The 4Kscore Can Potentially Reduce Unnecessary Prostate Biopsies in Men with Suspicious PSA in a Screening Population, J Urol 195(4S):e543, 2016. Presented at the American Urological Association (AUA) Meeting, San Diego, CA May 6-10, 2016
• Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua A, Crawford ED. Does Digital Rectal Exam Affect The 4Kscore Test for Aggressive Prostate Cancer? J Urol 195(4S):e646, 2016. Presented at the American Urological Association (AUA) Meeting, San Diego, CA May 6-10, 2016
• Werahera PN, Jasion EA, Crawford ED, Lucia MS, van Bokhoven A, Daily JW, Fernando FJ, La Rosa, FG. Diagnostic Accuracy of Prostate Biopsies can be Improved by Optical Characterization of Prostate Tissue. 95th Annual Meeting of the South Central Section of the AUA, Colorado Springs, CO, September 28 to October 1, 2016
• Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua A, Crawford ED. Does Digital Rectal Exam Affect The 4Kscore Test for Aggressive Prostate Cancer? 95th Annual Meeting of the South Central Section of the AUA, Colorado Springs, CO, September 28 to October 1, 2016
• Maccini M, Westfall N, Werahera PN, van Bokhoven A, Maroni PD, Wilson S, Glode M, Arangua P, Crawford ED. The 4Kscore Can Potentially Reduce Unnecessary Prostate Biopsies in Men with Suspicious PSA in a Screening Population. 95th Annual Meeting of the South Central Section of the AUA, Colorado Springs, CO, September 28 to October 1, 2016.
• Nickel JC, Stephens A, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Ehrlich GD. Assessment of the Lower Urinary Tract Microbiota during Symptom Flare in Women with Urologic Chronic Pelvic Pain Syndrome: A MAPP Network Study. J Urol. 2015 Sep 26. [Epub ahead of print] PubMed PMID: 26410734
• Martin AM, Nirschl TR, Nirschl CJ, Francica BJ, Kochel CM, van Bokhoven A, Meeker AK, Lucia MS, Anders RA, DeMarzo AM, Drake CG. Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance. Prostate Cancer Prostatic Dis. 2015 Dec;18(4):325-32. PubMed PMID: 26260996
• Hoque A, Yao S, Till C, Kristal AR, Goodman PJ, Hsing AW, Tangen CM, Platz EA, Stanczyk FZ, Reichardt JK, vanBokhoven A, Neuhouser ML, Santella RM, Figg WD, Price DK, Parnes HL, Lippman SM, Ambrosone CB, Thompson IM. Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease. Urology. 2015 Mar;85(3):616-20. PubMed PMID: 25733274
• Nickel JC, Stephens A, Landis JR, Chen J, Mullins C, van Bokhoven A, Lucia MS, Melton-Kreft R, Ehrlich GD. Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network. J Urol. 2015 Jul;194(1):127-35. PubMed PMID: 25596358
• Torkko KC, Wilson RS, Smith EE, Kusek JW, van Bokhoven A, Lucia MS. Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study. J Urol. 2015 Aug;194(2):454-61. PubMed PMID: 25828974
• Krieger JN, Stephens AJ, Landis JR, Clemens JQ, Kreder K, Lai HH, Afari N, Rodríguez L, Schaeffer A, Mackey S, Andriole GL, Williams DA. Relationship between chronic nonurological associated somatic syndromes and symptom severity in urological chronic pelvic pain syndromes: baseline evaluation of the MAPP study. J Urol. 2015 Apr;193(4):1254-62. PubMed PMID: 25444992
• Merrick DT, Edwards MG, Franklin WA, Sugita M, Miller Y, Friedman M, Dwyer-Nield L, Tennis M, Choo K, Hickey G, Kennedy T, van Bokhoven A, Heasley L, Hirsch FR, Bunn PA, Geraci M, Keith RL, Nemenoff R. Pathway Analysis of Gene Expression Profiles that Distinguish Persistent from Regressive Bronchial Dysplasia Indicate Synergistic Role for Polo-Like Kinase 1 (PLK1) and Epoxide Hydrolase 3 (EPHX3) in Malignant Progression. (ID 3334) 16th World Conference on Lung Cancer October September 6-9 2015, Denver, CO
• Merrick DT, Donald EJ, Olson D, Okeefe MC, Edwards MG, Franklin WA, Dwyer-Nield L, Orlicky D, Keith RL, Miller YE, Tennis M, Barón AE, Lu Z, van Bokhoven A, Malinowski H, Bunn PA, Geraci MW, Nemenoff R. Role of Inflammatory Infiltrates in Promoting Persistence or Regression of Bronchial Dysplasia. 16th World Conference on Lung Cancer October September 6-9 2015, Denver, CO
• Ostroff R, Mehan MR, Williams S, Niculescu-Mizil A, Franklin WA, Merrick DT, van Bokhoven A, Wolf H, Feser W, Baron A, Miller Y. Proteomic insights with lung cancer tumors based on histopathologic subtypes and genotypes. 16th World Conference on Lung Cancer October September 6-9 2015, Denver, CO
• Torkko KC, Till C, Goodman PJ, Tangen CM, van Bokhoven A, Lucia MS, Thompson Jr.IM, Peters U, Neuhouser ML. Interactions between finasteride and vitamin D-related polymorphisms is associated with prostate cancer risk in African American men. Seventh AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; November 9-12, 2014; San Antonio, TX Cancer Epidemiol Biomarkers Prev 2015 24; B18
• Merrick DT, Donald EJ, Olson D, O’Keefe MC, Edwards MG, Franklin WA, Dwyer-Nield L, Orlicky D, Keith RL, Miller YE, Tennis M, Baron A, Lu X, van Bokhoven A, Malinowski H, Bunn PA, Geraci M, Nemenoff R. Characterization of inflammatory infiltrates in persistent and regressive bronchial dysplasia (oral presentation), 2015 National Lung SPORE meeting.
• Nickel JC, Stephens A, Landis JR, Chen J, Mullins C, van Bokhoven A, Lucia MS, Melton-Kreft R, Ehrlich GD, The MAPP Research Network. Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network. J Urol. 2015 Jan 14. [Epub ahead of print] PubMed PMID: 25596358
• Werahera PN, Jasion EA, Crawford ED, La Rosa FG, Lucia MS, van Bokhoven A, Sullivan HT, Port JD, Maroni PD, Daily JW. Systematic diagnosis of prostate cancer using an optical biopsy needle adjunct with fluorescence spectroscopy. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug;2014:2165-8. PubMed PMID: 25570414
• Jonscher KR, Osypuk AA, van Bokhoven A, Lucia MS. Evaluation of urinary protein precipitation protocols for the multidisciplinary approach to the study of chronic pelvic pain research network. J Biomol Tech. 2014 Dec;25(4):118-26. PubMed PMID: 25365794
• Figg WD, Chau CH, Price DK, Till C, Goodman PJ, Cho Y, Varella-Garcia M, Reichardt JK, Tangen CM, Leach RJ, van Bokhoven A, Thompson IM, Lucia MS. Androgen receptor CAG repeat length and TMPRSS2:ETS prostate cancer risk: results From the Prostate Cancer Prevention Trial. Urology. 2014 Jul;84(1):127-31. PubMed PMID: 24824408
• Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ, MAPP Research Network Study Group. The MAPP research network: design, patient characterization and operations. BMC Urol. 2014 Aug 1;14:58. PubMed PMID: 25085119
• Clemens JQ, Mullins C, Kusek JW, Kirkali Z, Mayer EA, Rodríguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Buchwald D, Andriole GL, Lucia MS, Landis JR, Clauw DJ, MAPP Research Network Study Group. Clemens J, Kirkali Z, Kusek JW, Landis J, Lucia M, Mullins C, Pontari MA, Klumpp DJ, Schaeffer AJ, Apkarian AV, Cella D, Farmer MA, Fitzgerald C, Gershon R, Griffith JW, Heckman CJ 2nd, Jiang M, Keefer L, Marko DS, Michniewicz J, Parrish T, Tu F, Mayer A, Rodríguez LV, Alger J, Ashe-McNalley CP, Ellingson B, Heendeniya N, Kilpatrick L, Kutch J, Labus JS, Naliboff BD, Randal F, Smith SR, Kreder KJ, Bradley CS, Eno M, Greiner K, Luo Y, Lutgendorf SK, O'Donnell MA, Ziegler B, Clauw DJ, Clemens J, As-Sanie S, Berry S, Halvorson ME, Harris R, Harte S, Ichesco E, Oldendorf A, Scott KA, Williams DA, Buchwald D, Afari N, Krieger J, Miller J, Richey S, Ross SO, Spiro R, Sundsvold TJ, Strachan E, Yang CC, Andriole GL, Lai H, Bristol RL, Colditz G, Deutsch G, Gardner VC, Gereau RW 4th, Henderson JP, Hong BA, Hooton TM, Ness TJ, North CS, Spitznagle TM, Sutcliffe S, Landis J, Barrell T, Hanno P, Hou X, Howard T, Pontari MA, Robinson N, Stephens A, Wang Y, Lucia M, van Bokhoven A, Osypuk AA, Dayton R Jr, Jonscher KR, Sullivan HT, Wilson R, Ehrlich GD, Moses MA, Briscoe AC, Briscoe D, Curatolo A, Froehlich J, Lee RS, Sachdev M, Solomon KR, Steen H, Mackey S, Bagarinao E, Foster LC, Hubbard E, Johnson KA, Martucci KT, McCue RL, Moericke RR, Nilakantan A, Noor N, Nickel J, Mullins C, Kusek JW, Kirkali Z, Bavendam TG.The MAPP research network: a novel study of urologic chronic pelvic pain syndromes. BMC Urol. 2014 Aug 1;14:57. PubMed PMID: 25085007
• Lucia MS, van Bokhoven A. (2014) Biorepository Quality Assurance. In: Linda M. McManus, Richard N. Mitchell, editors. Pathobiology of Human Disease. San Diego: Elsevier; 2014. p. 3040-3045
• van Bokhoven A (2014) Biorepository Operations and Infrastructure. In: Linda M. McManus, Richard N. Mitchell, editors. Pathobiology of Human Disease. San Diego: Elsevier; 2014. p. 3030-3034.
• Lucia MS, van Bokhoven A, Infrastructure of the Biospecimen Repository and Associated Core Labs. Donna E. Hansel, Scott D. Jewell, Editors. Developing and Organizing an Institutional Biospecimen Repository. North Field: CAP Press: 2014. p. 23-32
• van Bokhoven, A, Lucia, MS Biorepository Operations and Infrastructure, Chapter in: Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms.
• Lucia, MS, van Bokhoven, A. Biorepository Quality Assurance, Chapter in: Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms
• Werahera PN, Crawford ED, La Rosa FG, Torkko KC, Schulte B, Sullivan HT, van Bokhoven A, Lucia MS, Kim FJ. Anterior tumors of the prostate: diagnosis and significance. Can J Urol. 2013 Oct;20(5):6897-906. PubMed PMID: 24128826
• Infrastructure of the Biospecimen Repository and Associated Core Laboratories. Lucia MS, van Bokhoven A CAP Monographs, In press 2013.
• J.R. Diamond, A.C. Tan, T.M. Pitts, A. van Bokhoven , D. Aisner , A.D. Elias, V.F. Borges, K. D. Miller, S.G. Eckhardt, J.J. Tentler. A Phase II Clinical Trial of ENMD-2076 in Metastatic Triple-Negative Breast Cancer: Translating a p53-based Biomarker from Bench to Bedside 11th International Symposium on Targeted Anticancer Therapies (TAT 2013), Paris, France, March 4-6, 2013 #51 2013
• Werahera PN, Jasion AE, Liu Y, Daily JW, Nash R, Batte E, Arangua P, La Rosa FG, Maroni PD, Lucia MS, van Bokhoven A, Sullivan HT, Jones C, Lux K, Crawford ED Fluorescence spectroscopy adjutant optical biopsy needle for prostate cancer diagnosis: first-in-human study results 23rd International Prostate Cancer Update, Vail, CO, 2013
• Nickel JC, Stephens A, Chen J, Melton-Kreft R, Spirk T, Earl J, O'Toole M, Costerton JW, van Bokhoven A, Mullins C, Ehrlich G Application of State-of-the-Art Methods to Search for Microbial Contributions to the Etiology of Urological Chronic Pelvic Pain Syndrome (UCPPS) American Urological Association Annual Meeting, 4-8 May, 2013 San Diego, CA
• Lucia MS, van Bokhoven A. Temporal Changes in the Pathologic Assessment of Prostate Cancer. JNCI Monograph, In Press 2012
• Lucia MS, van Bokhoven A. Temporal Changes in the Pathologic Assessment of Prostate Cancer. JNCI Monograph, J Natl Cancer Inst Monogr 2012(45):157-61, 2012 [PMID 23271767]
• Aimola P, Carmignani M, Volpe AR, Di Benedetto A, Claudio L, Waalkes MP, van Bokhoven A, Tokar EJ, Claudio PP. Cadmium induces p53-dependent apoptosis in human prostate epithelial cells. PLoS One. 2012;7(3):e33647 2012 PMID:22448262
• Kristal AR, Till C, Tangen CM, Goodman PJ, Neuhouser ML, Stanczyk FZ, Chu LW, Patel SK, Thompson IM, Reichardt JK, Hoque A, Platz EA, Figg WD, van Bokhoven A, Lippman SM, Hsing AW. Associations of serum sex steroid hormone and 5a-androstane-3a,17ß-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride. Cancer Epidemiol Biomarkers Prev. 10:1823-32. 2012 PMID: 22879203
• Torkko K, van Bokhoven A, Maroni P, Lucia MS, McCartney S, Sullivan HT, Fulmer J, Shappell SB, Crawford ED. Urine PCA3 Testing for the Early Detection of Prostate Cancer. Feasibility, Test Performance, and Age and Race Associations Compared To Serum PSA in A Multi-Ethnic Population Over Four Years. #1909, American Urological Association Annual Meeting, 14-19 May, 2011 Washington, DC. J Urol 185[4, supplement], e763, 2011 - Presenter
• Werahera PN, Jasion EA, La Rosa FG, Lucia MS, Crawford ED, Maroni PD, van Bokhoven A, Port D, Sullivan HT, O’Donnell C, Kim FJ, Daily JW. Minimally invasive 16G optical biopsy needle for prostate cancer diagnosis. #2137. American Urological Association Annual Meeting, 14-19 May, 2011 Washington, DC. J Urol 185[4, supplement], e855-856, 2011
• Thudi NK, Shu ST, Martin CK, Lanigan LG, Nadella MV, van Bokhoven A, Werbeck JL, Simmons JK, Murahari S, Kisseberth WC, Breen M, Williams C, Chen CS, McCauley LK, Keller ET, Rosol TJ. Development of a brain metastatic canine prostate cancer cell line. The Prostate 71:1251-1263, 2011
• Flaig TW, Wilson S, van Bokhoven A, Varella-Garcia M, Wolfe P, Maroni P, Genova EE, Morales D, Lucia MS. Detection of circulating tumor cells in metastatic and clinically localized urothelial carcinoma. Urology, 78: 863-7. 2011
• Lucia MS, van Bokhoven A. Requisite for Collection and Distribution of Tissue and Fluid Specimens in Molecular Diagnostics. In: Precision Molecular Pathology of Bladder Cancer, Hansel D.E. and Lerner S.P., eds. Springer International