Sonia Flores, PhD

Publications

• Hines, I.N., Harada, H., Flores, S., Gao, B., McCord, J.M., and Grisham, M.B. Endothelial nitric oxide synthase protects the post-ischemic liver: potential interactions with superoxide. Biomedicine & Pharmacotherapy, 59(4):183-9, 2005.
• Evidence for vascular remodeling in the lungs of macaques infected with simian immunodeficiency virus/HIV NEF recombinant virus. Chest. 2005 Dec;128(6 Suppl):621S-622S
• Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice.Free Radic Biol Med. 2005 Oct 15;39(8):1089-98.
• HIV-1 Nef is associated with severe angioproliferative pulmonary arterial disease in SHIV-nef infected macaques, AJRCCM
• HIV-1 Nef is associated with severe angioproliferative pulmonary arterial disease in SHIV-nef infected macaques, Amer.J.Resp.Critical Care Med. 174:437-445, 2006
• Pathology of Pulmonary Hypertension, Clinics in Chest Medicine,
• Tuder, R.M., Marecki, J.C. Richter, A, Fijalkowska, I., Flores, S.C., Pathology of Pulmonary Hypertension, Clinics in Chest Medicine, 28(1):23-42, 2007
• Nicolls, M.R., Haskins, K. and Flores S.C. Oxidant stress, immune dysregulation, and vascular function in type I diabetes. Antioxid Redox Signal. 9(7):879-89, 2007
• Petrache, I.,Stephens, R.S., Diab,K., Knox, K.S., Twigg, H.L., Flores, S.C., and Tuder, R.M., HIV- associated pulmonary emphysema. A review of the literature and inquiry into its mechanism, Thorax, in press
• HIV-Mediated Innate Immunity and Mycobacterium Exposure J. Honda1,; E. Chan2; I. Orme3, S. Flores,1. American Thoracic Society Meeting, Toronto, May 16-21, 2008
• “The Effect of Vitamin D on HIV and Mycobacteria in Human Monocytes” J. Honda1,; E. Chan2; I. Orme3, S. Flores,1. American Society of Microbiology General Meeting Boston June 1-5, 2008 *** Travel Grant: Hirs UCD Graduate School Award and an ASM Travel Grant
• “The Effects of 1,25(OH)2D3 On HIV and Mycobacterium” Jennifer R. Honda1,2,3; Edward Chan4; Sonia Flores,2,3. RMB ASM Spring Meeting Abstract: April 12, 2008 ***1st place graduate student oral presentation.
• Twigg HL 3rd, Morris A, Ghedin E, Curtis JL, Huffnagle GB, Crothers K, Campbell TB, Flores SC, Fontenot AP, Beck JM, Huang L, Lynch S, Knox KS, Weinstock G, Lung HIV Microbiome Project. Use of bronchoalveolar lavage to assess the respiratory microbiome: signal in the noise. Lancet Respir Med. 2013 Jul;1(5):354-6. PubMed PMID: 24429191
• Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Muc5b is required for airway defence. Nature. 2014 Jan 16;505(7483):412-6. PubMed PMID: 24317696
• Lozupone CA, Li M, Campbell TB, Flores SC, Linderman D, Gebert MJ, Knight R, Fontenot AP, Palmer BE. Alterations in the gut microbiota associated with HIV-1 infection. Cell Host Microbe. 2013 Sep 11;14(3):329-39. PubMed PMID: 24034618
• Flores SC, Almodovar S. Human immunodeficiency virus, herpes virus infections, and pulmonary vascular disease. Pulm Circ. 2013 Jan;3(1):165-70. PubMed PMID: 23662195
• Morris A, Beck JM, Schloss PD, Campbell TB, Crothers K, Curtis JL, Flores SC, Fontenot AP, Ghedin E, Huang L, Jablonski K, Kleerup E, Lynch SV, Sodergren E, Twigg H, Young VB, Bassis CM, Venkataraman A, Schmidt TM, Weinstock GM, Lung HIV Microbiome Project. Comparison of the respiratory microbiome in healthy nonsmokers and smokers. Am J Respir Crit Care Med. 2013 May 15;187(10):1067-75. PubMed PMID: 23491408
• Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP, Lung HIV Microbiome Project. Widespread colonization of the lung by Tropheryma whipplei in HIV infection. Am J Respir Crit Care Med. 2013 May 15;187(10):1110-7. PubMed PMID: 23392441
• Neff CP, Chain JL, MaWhinney S, Martin AK, Linderman DJ, Flores SC, Campbell TB, Palmer BE, Fontenot AP. Lymphocytic Alveolitis is Associated with the Accumulation of Functionally Impaired HIV-specific T Cells in the Lung of ART-naive Subjects. Am J Respir Crit Care Med. 2014 Dec 23. [Epub ahead of print] PubMed PMID: 25536276
• Almodovar S., Adamson L., Luciw P., Voelkel N., Flores S.C. SHIV-nef-induced complex pulmonary vascular lesions in Rhesus macaques (Poster); 25th Annual Symposium on Non Human Primate Models for AIDS; Monterrey, CA
• Honda JR, Connick E, MaWhinney S, Chan ED, Flores SC. Plasma LL-37 correlates with vitamin D and is reduced in human immunodeficiency virus-1 infected individuals not receiving antiretroviral therapy. J Med Microbiol. 2014 Jul;63(Pt 7):997-1003. PubMed PMID: 24821067
• Wang T, Green LA, Gupta SK, Kim C, Wang L, Almodovar S, Flores SC, Prudovsky IA, Jolicoeur P, Liu Z, Clauss M. Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction. PLoS One. 2014;9(3):e91063. PubMed PMID: 24608713
• Almodovar S., Adamson L., Luciw P., Voelkel N., Flores S.C. SHIV-nef-induced complex pulmonary vascular lesions in Rhesus macaques (Poster); 25th Annual Symposium on Non Human Primate Models for AIDS; Monterrey, CAMANUSCRIPTS
• Beck JM, Schloss PD, Venkataraman A, Twigg H 3rd, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB. Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1335-44. PubMed PMID: 26247840
• Honda JR, Hess T, Malcolm KC, Ovrutsky AR, Bai X, Irani VR, Dobos KM, Chan ED, Flores SC. Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. PLoS One. 2015;10(5):e0126994. PubMed PMID: 25993058
• Neff CP, Chain JL, MaWhinney S, Martin AK, Linderman DJ, Flores SC, Campbell TB, Palmer BE, Fontenot AP. Lymphocytic alveolitis is associated with the accumulation of functionally impaired HIV-specific T cells in the lung of antiretroviral therapy-naive subjects. Am J Respir Crit Care Med. 2015 Feb 15;191(4):464-73. PubMed PMID: 25536276
• Almodovar S., Knight R., Allshouse A., Lozupone C., McDonald D., Widmann J., Voelkel N.F., Shelton RJ., Goujard C., Petrosillo N., Simonneau G., Humbert M., Flores S.C. HIV-related Pulmonary Arterial Hypertension is Associated with Specific Sequence Variations in HIV-1 Nef Functional Domains. Pending submission to PLoS Medicine.
• Almodovar S., Knight R., Allshouse A., Giavedoni, L., Long C., Gilman J., Voelkel N.F., Luciw P., Flores S.C. Severe lung vascular remodeling is associated with plasma cytokine changes and right ventricular hypertrophy markers in rhesus macaques infected with chimeric SHIVnef. To be submitted to Journal of Virology.
• Morris A, Flores SC. Study of the Lung Microbiome. Have We Reached the End of the Beginning?. Am J Respir Crit Care Med. 2017 Jan 1;195(1):15-16. PubMed PMID: 28035854
• Leader JK, Crothers K, Huang L, King MA, Morris A, Thompson BW, Flores SC, Drummond MB, Rom WN, Diaz PT. Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort. J Acquir Immune Defic Syndr. 2016 Apr 1;71(4):420-7. PubMed PMID: 26914911
• Duncan GA, Lockett A, Villegas LR, Almodovar S, Gomez JL, Flores SC, Wilkes DS, Tigno XT. National Heart, Lung, and Blood Institute Workshop Summary: Enhancing Opportunities for Training and Retention of a Diverse Biomedical Workforce. Ann Am Thorac Soc. 2016 Apr;13(4):562-7. PubMed PMID: 27058184
• Honda, J.R., Agerberth, B, Flores, S. C. “Vitamin D Inhibits Mycobacterium avium complex via Cathelicidin Independent Mechanisms” In preparation
• Honda, J.R. Flores, S.C. “HIV impairs Vitamin D-Mediated Killing of Mycobacterium avium complex in human monocytes” In preparation
• Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC. Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques. Viral Immunol. 2017 Dec 19. [Epub ahead of print] PubMed PMID: 29256819
• Presti RM, Flores SC, Palmer BE, Atkinson JJ, Lesko CR, Lau B, Fontenot AP, Roman J, McDyer JF, Twigg HL 3rd. Mechanisms Underlying HIV-Associated Noninfectious Lung Disease. Chest. 2017 Nov;152(5):1053-1060. PubMed PMID: 28427967
• Morris A, Flores SC. Study of the Lung Microbiome. Have We Reached the End of the Beginning?. Am J Respir Crit Care Med. 2017 Jan 1;195(1):15-16. PubMed PMID: 28035854
• Honda, J. R., Connick, L., Flores, S.C. “Vitamin D and Cathelicidin in HIV Infected Patients” In Preparation
• Honda, J.R., Ordway-Rodriguez, D., Shang, S., Orme, I., Flores, S.C. “Characterization of highly pathogenic Mycobacterium tuberculosis SA161 in Lung Infection of human immunodeficiency virus type 1 Tat transgenic mice”
• Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC. Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques. Viral Immunol. 2018 Apr;31(3):206-222. PubMed PMID: 29256819
• Pravin B. Sehgal, Somshuvra Mukhopadhyay, Kirit Patel, Fang Xu Sharilyn Almodóvar, Rubin M. Tuder and Sonia C. Flores Golgi dysfunction is a common feature of idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques, submitted to AJP-Lung
• Adela Cota-Gomez, Natalia C. Flores, Ariana C. Flores, Xiaofeng, Ling, Robert Shelton, Michelle Kerklo and Sonia C. Flores, Lung-specific expression of the HIV-1 Tat protein increases oxidant stress and resets the basal threshold for inflammation" to be submitted to AJP
• Plenary Talk, Lung Complications of HIV Infection, ATS Meeting, Toronto, May 2008 Title: Pulmonary Arterial Hypertension and HIV-1 Nef Protein
• International Pulmonary Arterial Hypertension Meeting, Dana Pointe, February 2008 Title: Viral and other Infectious Etiologies in PAH
• Caulfield T, Coban M, Tek A, Flores SC. Molecular Dynamics Simulations Suggest a Non-Doublet Decoding Model of -1 Frameshifting by tRNA(Ser3). Biomolecules. 2019 Nov 18;9(11). PubMed PMID: 31752208
• Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol. 2020 Mar;62(3):354-363. PubMed PMID: 31545652
• Invited Speaker, American Heart Association Annual Meeting, Nov. 2008, New Orleans Title: HIV Infection and Pulmonary Arterial Hypertension
• Invited Speaker, RISE Seminar Series, Cayey, PR Sept. 2008 Title: How to become a successful scientist and a role model by studying HIV
• Invited Speaker, Ponce School of Medicine, Sept 2008 Title: HIV nef and pulmonary hypertension: from monkeys to humans to the bench
• Segarra VA, Vega LR, Primus C, Etson C, Guillory AN, Edwards A, Flores SC, Fry C, Ingram SL, Lawson M, McGee R, Paxson S, Phelan L, Suggs K, Vuong E, Hammonds-Odie L, Leibowitz MJ, Zavala M, Lujan JL, Ramirez-Alvarado M. Scientific Societies Fostering Inclusive Scientific Environments through Travel Awards: Current Practices and Recommendations. CBE Life Sci Educ. 2020 Jun;19(2):es3. PubMed PMID: 32453676
• Segarra VA, Primus C, Unguez GA, Edwards A, Etson C, Flores SC, Fry C, Guillory AN, Ingram SL, Lawson M, McGee R, Paxson S, Phelan L, Suggs K, Vega LR, Vuong E, Havran JC, Leon A, Burton MD, Lujan JL, Ramirez-Alvarado M. Scientific societies fostering inclusivity through speaker diversity in annual meeting programming: a call to action. Mol Biol Cell. 2020 Nov 1;31(23):2495-2501. PubMed PMID: 33119460
• Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, Huang L, Kessing CF, Suarez-Martinez EB, Pruitt K, Hsue PY, Tyor WR, Flores SC, Sutliff RL. HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension. Sci Rep. 2020 Jul 16;10(1):11696. PubMed PMID: 32678115
• Distinguished Scientist seminar Speaker, Mobile, AL Jan 2009 Title: Pulmonary Hypertension and HIV Nef: from monkeys to humans
• Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol. 2020 Mar;62(3):354-363. PubMed PMID: 31545652
• Burden, M, Flores, SC , Schwartz, DA. . COVID-19: A Time to Reinvest in Our Scientists. J Respir Crit Care Med 2021 May 1;203(9):1190-1191. PMID: 33596390
• Invited Speaker, Reunion Neumologica, La Toja, Spain; Feb 2009 Title: Hipertension Arterial Pulmonar y la Proteina Nef del Virus de Immunodeficiencia Humana
• Pino-Jones AD, Cervantes L, Flores S, Jones CD, Keach J, Ngov LK, Schwartz DA, Wierman M, Anstett T, Bowden K, Keniston A, Burden M. Advancing Diversity, Equity, and Inclusion in Hospital Medicine. J Hosp Med. 2021 Apr;16(4):198-203. PubMed PMID: 33617435
• Segarra VA, Primus C, Unguez GA, Edwards A, Etson C, Flores SC, Fry C, Guillory AN, Ingram SL, Lawson M, McGee R, Paxson S, Phelan L, Suggs K, Vega LR, Vuong E, Havran JC, Leon A, Burton MD, Lujan JL, Ramirez-Alvarado M. Scientific societies fostering inclusivity through speaker diversity in annual meeting programming: a call to action. Mol Biol Cell. 2020 Nov 1;31(23):2495-2501. PubMed PMID: 33119460
• Segarra VA, Vega LR, Primus C, Etson C, Guillory AN, Edwards A, Flores SC, Fry C, Ingram SL, Lawson M, McGee R, Paxson S, Phelan L, Suggs K, Vuong E, Hammonds-Odie L, Leibowitz MJ, Zavala M, Lujan JL, Ramirez-Alvarado M. Scientific Societies Fostering Inclusive Scientific Environments through Travel Awards: Current Practices and Recommendations. CBE Life Sci Educ. 2020 Jun;19(2):es3. PubMed PMID: 32453676
• Pulmonary Vascular Research Institute Hot Topics, Mexico, January 2009 Title: Mutations in amino acid residues in HIV-1 Nef may act as triggers of endothelial cell injury/proliferation in HIV-related pulmonary hypertension
• Zimmerman, M.A.;Haskins, K. Bradley, B.; Gilman, J.; Gamboni-Robertson, F. and Flores, S.C.; Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus; J. Surgical Research, 2011, in press
• Lee JE, Patel K, Almodovar S, Tuder R, Flores SC, Sehgal PB. Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2011 Jan 7. [Epub ahead of print]
• Almodovar S, Cicalini S, Petrosillo N, Flores SC. Pulmonary hypertension associated with HIV infection: pulmonary vascular disease: the global perspective. Chest. 2010 Jun;137(6 Suppl):6S-12S. PubMed PMID: 20522575; PubMed Central PMCID: PMC2882114.
• Cicalini S, Almodovar S, Grilli E, Flores S. Pulmonary Hypertension and HIV infection: epidemiology, pathogenesis, and clinical approach. Clin Microbiol Infect. 2010 Jun 8. [Epub ahead of print] PubMed PMID: 20545962.
• Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC. Pathogenesis of HIV-associated Pulmonary Hypertension: Potential Role of HIV-1 nef. The Proceedings of the American Thoracic Society (2011); accepted for publication.
• Almodovar, S. Flores, SC: A Macaque Model for Pulmonary Hypertension Associated with HIV; Drug Discovery Today: Disease Models, 2011, accepted for publication
• Almodovar S, Flores SC. Inflammation in HIV-Associated Pulmonary Hypertension: Cause or Effect? Advances in Pulmonary Hypertension; in press.
• Almodovar S, Morelli J, Hakar M, Gilman J, Niemeyer B, Flores AC, Sokas C, Hsue PY, Flores SC. Expediting diagnosis of HIV-related pulmonary hypertension from the bench: HIV-1 nef sequences as genetic translational tools. Presented at the Thomas L. Petty Aspen Lung Conference, 53rd Annual Meeting on "Systems Biology of Lung Diseases - Progress in the 'Omics' Era," 2010, Aspen, Colorado.
• Almodovar S, Allshouse A, Knight R, Roemer S, Voelkel NF, Hsue PY, Humbert M, Flores SC. HIV-1 Nef Signature Sequences Are A Feature Of HIV-related Pulmonary Hypertension: A Genetic Translational Tool? Am J Respir Crit Care Med 181;2010:A5209. New Orleans, Louisiana
• Cota-Gomez, A.; Flores, AC; Ling, X; P:iganelli, J.D.; Garcia, M.V. Flores, S.C; HIV-1 Tat Increases Oxidant Burden in the Lungs of Transgenic Mice; Free Radical Biology and Medicine, 2011, submitted after revision
• J. HONDA, E.D. Chan, B. Agerberth, S.C. Flores.Non-tuberculous mycobacteria are resistant to the antimicrobial peptide cathelicidin; UCD Fall Research Symposia
• J.R. HONDA, E.D. Chan, S.C. Flores; Vitamin D, Cathelicidin and Mycobacterium In HIV Infection;Keystone Symposia NIAID Scholarship Award to attend and present research findings at “Overcoming the Crisis of TB and AIDS” Conference. Kilimanjaro, Tanzania
• J.R. HONDA, E.D. Chan, S.C.Flores;Relationship Between Vitamin D and Cathelicidin Levels in HIV-Infected and Uninfected Denver Residents; Keystone Symposia HIV Evolution, Genomics, and Pathogenesis. Whistler, BC
• Honda JR a*, Shang, S b** Shanley, CA b, Caraway ML b, Henao-Tamayo M b, Chan ED c, Basaraba, Randall b, Orme IM b, Orme, DJ b**, Flores, SC a. Immune responses of HIV-1 tat transgenic mice to mycobacterium tuberbulosis w-Beijing sa161. The Open AIDS Journal, 2011 vol. 5, In press.
• Cota-Gomez A, Flores AC, Ling XF, Varella-Garcia M, Flores SC. HIV-1 Tat increases oxidant burden in the lungs of transgenic mice. Free Radic Biol Med. 2011 Aug 5. [Epub ahead of print] PubMed PMID: 21855628.
• Zimmerman MA, Haskins K, Bradley B, Gilman J, Gamboni-Robertson F, Flores SC. Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus. J Surg Res. 2011 Jun 15; 168(2):e195-202. Epub 2011 Feb 26. PubMed PMID: 21470634; PubMed Central PMCID: PMC3091976.
• Crothers K, Thompson BW, Burkhardt K, Morris A, Flores SC, Diaz PT, Chaisson RE, Kirk GD, Rom WN, Huang L; Lung HIV Study. HIV-associated lung infections and complications in the era of combination antiretroviral therapy. Proc Am Thorac Soc. 2011 June; 8(3):275-81. PubMed PMID: 21653528; PubMed Central PMCID: PMC 3132785.
• Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC; Lung HIV Study. Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef. Proc Am Thorc Soc. 2011 June; 8(3):308-12. PubMed PMID: 21653533; PubMed Central PMCID: PMC 3132790.
• Crothers K, Thompson BW, Burkhardt K, Morris A, Flores SC, Diaz PT, Chaisson RE, Kirk GD, Rom WN, Huang L; Lung HIV Study. HIV-associated lung infections and complications in the era of combination antiretroviral therapy. Proc Am Thorac Soc. 2011 Jun; 8(3):275-81. PubMed PMID: 21653528; PubMed Central PMCID: PMC3132785.
• Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC; Lung HIV Study. Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef. Proc Am Thorac Soc. 2011 Jun; 8(3):308-12. PubMed PMID: 21653533; PubMed Central PMCID: PMC3132790.
• Zimmerman MA, Haskins K, Bradley B, Gilman J, Gamboni-Robertson F, Flores SC. Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus. J Surg Res. 2011 Jun 15; 168(2): e195-202. Epub 2011 Feb 26. PubMed PMID: 21470634; PubMed Central PMCID: PMC 3091976.
• Almodovar S, Knight R, Allshouse AA, Roemer S, Lozupone C, McDonald D, Widmann JJ, Voelkel N, Shelton RJ, Suarez-Martinez EB, Hammer K, Goujard CM, Petrosillo N, Simonneau G, Hsue PY, Humbert M, Flores SC. Human Immunodeficiency Virus nef Signature Sequences are Associated with Pulmonary Hypertension. AIDS Res Hum Retroviruses. 2012; 28(6):607-18. PMID: 22066947
• Widespread Colonization of the Lung by Tropheryma whipplei in HIV Infection. Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP; for the Lung HIV Microbiome Project. Am J Respir Crit Care Med. 2013 Feb 7. [Epub ahead of print] PMID:23392441