Jesse Davidson, MD, MPH/MSPH

Professional Titles

• Associate Professor, Pediatrics
• Associate Medical Director, Children's Hospital Colorado Research Institute

Recognitions

• Research Leaders Academy, American Heart Association (2017)
  Twice selected as one of 300 national research leaders in adult and pediatric cardiology to participate in a three-day academy to explore and debate research issues, develop a network for senior and future CVD and Stroke research thought leaders, and advance AHA Mission and encourage AHA engagement through Academy research network.

Research Interests

1) Alkaline phosphatase in infant cardiopulmonary bypass: In 2012 our group identified an unexpected finding of markedly decreased alkaline phosphatase activity immediately following cardiothoracic surgery in infants with congenital heart disease. Lower alkaline phosphatase activity was strongly associated with increased intensity and duration of post-operative support. Given recent studies demonstrating potential novel protective effects of alkaline phosphatase such as dephosphorylation of endotoxin and extracellular adenine nucleotides, we became intrigued about alkaline phosphatase as a potential therapy to prevent intestinal and kidney injury following cardiac surgery in our high risk patients with congenital heart disease. I was awarded a K23 grant from the NIH/NHLBI to further assess alkaline phosphatase as a biomarker in this population as well as a potential therapeutic target to aid in clearance of harmful extracellular adenine nucleotides and endotoxin. I have also recently developed a large animal model of infant cardiopulmonary bypass and deep hypothermic circulatory arrest funded by the American Heart Association and Department of Defense in order to both test novel therapeutics (including alkaline phosphatase) as well as to study the mechanisms of post-operative multi-organ injury. a. Jesse A. Davidson, Tracy Urban, Suhong Tong, Mark Twite, Alan Woodruff, Paul E. Wischmeyer, Jelena Klawitter. Alkaline phosphatase, soluble extracellular adenine nucleotides, and adenosine production after infant cardiopulmonary bypass. PLOS One 2016; 1-15. b. Jesse Davidson, Tracy Urban, Suhong Tong, Christine Baird, Mark Twite, James Jaggers, Eric Simoes, Paul Wischmeyer. Alkaline phosphatase in infant cardiopulmonary bypass: kinetics and relationship to organ injury and major cardiovascular events. Journal of Pediatrics 2017 Nov; 109:49-55. c. Jesse A. Davidson, Tracy T. Urban, Suhong Tong, Aline Maddux, Gerald Hill, Benjamin S. Frank, John D. Watson, James Jaggers, Eric A. F. Simões, Paul Wischmeyer. Alkaline Phosphatase Activity and Endotoxemia after Infant Cardiothoracic Surgery. Shock 2019; 51(3), 328-336. d. Jesse A. Davidson, Ludmila Khailova, Amy Treece, Justin Robison, Danielle E. Soranno, James Jaggers, Richard J. Ing, Scott Lawson, Suzanne Osorio Lujan. Alkaline Phosphatase Treatment of Acute Kidney Injury in an Infant Piglet Model of Cardiopulmonary Bypass with Deep Hypothermic Circulatory Arrest. Scientific Reports 2019. 2) Biomarkers and associated outcomes after infant cardiothoracic surgery: I began research in this area by examining the utility of procalcitonin to distinguish the post-operative systemic inflammatory response from post-operative infection in 70 infants undergoing cardiothoracic surgery. I have also explored CD73 levels in our infants as an adjunct to my work with alkaline phosphatase and adenosine metabolism. In my most expansive biomarker work to date, I leveraged my K23 cohort to begin exploring the global metabolic shift that occurs following infant cardiac surgery. These findings were recently published in Journal of the American Heart Association. a. Davidson J, Tong S, Hauck A, Lawson DS, Jaggers J, Kaufman J, Da Cruz E. Alkaline phosphatase activity after cardiothoracic surgery in infants and correlation with post-operative support and inflammation: a prospective cohort study. Critical Care. 2012 Aug 20: 16(4): R160. b. Davidson J, Tong S, Hauck A, Lawson DS, Da Cruz E, Kaufman J. The kinetics of procalcitonin and C-reactive protein and the relationship to post-operative infection in young infants undergoing cardiovascular surgery. Ped Res. 2013 Sep; doi:10.1038/pr.2013.124 c. Jessica N. Persson, Christine H. Baird, Suhong Tong, Tracy T Urban, Jelena Klawitter, Paul E. Wischmeyer, and Jesse A. Davidson. Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity. Ped. Res. 2017; doi:10.1038/pr.2017.325 d. Jesse A. Davidson, MD, MPH; Zachary Pfeifer, BS; Benjamin Frank, MD; Suhong Tong, MS; Tracy T. Urban, BS; Paul A. Wischmeyer, MD; Peter Mourani, MD; Bruce Landeck, MD; Uwe Christians, MD, PhD; Jelena Klawitter, PhD. Metabolomic fingerprinting of infants undergoing cardiopulmonary bypass: changes in metabolic pathways and association with mortality and cardiac intensive care unit length of stay. J Am Heart Assoc. 2018;7:e010711. 3) Biomarkers of ventricular remodeling and pulmonary vascular development in congenital heart disease: In this new research area, my colleague Dr. Benjamin Frank and I are working to understand the critical molecular pathways involved in pathologic ventricular and pulmonary vascular development in patients with congenital heart disease. We began work by evaluating left ventricular hypertrophy and remodeling ~1 year after surgical repair of left sided obstructive lesions. The data from that project have been published, identifying endothelin-1 as a novel potential biomarker in this disease. More recently, we began a larger project exploring endothelin-1 in the single ventricle heart disease population as well as the metabolomic and proteomic patterns associated with poor pulmonary blood vessel growth prior to stage 2 palliation and post-operative hypoxemia. This project was awarded an AHA Innovative Award and the enrolled cohort will be followed longitudinally through the Fontan operation. a. Benjamin Steven Frank, Tracy T Urban, Suhong Tong, Courtney Cassidy, Max B Mitchell, Christopher S Nichols and Jesse A. Davidson. Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair. World Journal of Cardiology. 2017 Dec; 9(12):822-829. b. Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA. Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta. Congenit Heart Dis. 2019 Jan 16. 4) Post-operative care in infants undergoing cardiac surgery: My initial interest in the study of post-operative care focused on vasoactive/inotropic support in the post-operative period. From a sub-analysis of my procalcitonin cohort I was able to validate the vasoactive-inotropic score initially reported by Gaies, et al., which we have now also validated in pediatric sepsis. Over the past two years I helped spearhead a multicenter collaborative, funded by the Gerber Foundation, that leverages automated data extraction to explore multiple aspects of repeated measure intensive care variables in our post-operative patients. The five centers involved have collected data on fluid, ventilator, and sedation practices in over 500 infants undergoing the Norwood procedure. a. Davidson J, Tong S, Hancock H, Hauck A, Da Cruz E, Kaufman J. Prospective validation of the vasoactive-inotropic score and correlation to short-term outcomes in neonates and infants after cardiothoracic surgery. Intensive Care Med. 2012 Jul; 38(7): 1184-90. b. Amanda M. McIntosh, Suhong Tong, Sara J. Deakyne, [*Jesse A. Davidson, *Halden F. Scott] *Co-senior authors. Validation of the Vasoactive Inotropic Score in Pediatric Sepsis. Ped Crit Care Med. 2017 Oct;18(10):1003-1005.

Publications

• Davidson J, Tong S, Hauck A, Lawson DS, da Cruz E, Kaufman J. Kinetics of procalcitonin and C-reactive protein and the relationship to postoperative infection in young infants undergoing cardiovascular surgery. Pediatr Res. 2013 Oct;74(4):413-9. PubMed PMID: 23863853
• CONTINUOUS OCTREOTIDE INFUSION FOR SULFONYLUREA-INDUCED HYPOGLYCEMIA IN A TODDLER The Journal of Emergency Medicine, Vol. 45, No. 6, pp. e209–e213, 2013 Rebecca Llamado, MD, Angela Czaja, MD, MSC, Nicholas Stence, MD, and Jesse Davidson, MD, MPH
• Francois Lacour-Gayet, Leo Lopez, Jesse Davidson, Eduardo da Cruz. Pulmonary Venous Stenosis. In book: Textbook of Pediatric and Congenital Cardiology, Cardiac Surgery and Cardiac Intensive Care, Edition: 1st, Publisher: Springer-Verlag London Ltd.
• Dominguez SR, Martin B, Heizer H, Jone PN, Tong S, Davidson J, Anderson MS, Glodé MP. Procalcitonin (PCT) and Kawasaki Disease: Does PCT Correlate with IVIG-Resistant Disease, Admission to the Intensive Care Unit, or Development of Coronary Artery Lesions?. J Pediatric Infect Dis Soc. 2015 Apr 20. [Epub ahead of print] PubMed PMID: 26407256
• Jone PN, Tapia D, Davidson J, Fagan TE, Browne L, Ing RJ, Kay J. Successful Treatment of Myocardial Infarction in an Infant With Kawasaki Disease. Semin Cardiothorac Vasc Anesth. 2015 Sep;19(3):255-9. PubMed PMID: 25700695
• Davidson JA, Urban TT, Baird C, Tong S, Woodruff A, Twite M, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase in Infant Cardiopulmonary Bypass: Kinetics and Relationship to Organ Injury and Major Cardiovascular Events. J Pediatr. 2017 Nov;190:49-55.e2. PubMed PMID: 29144270
• McIntosh AM, Davidson JA, Scott HF. The authors reply. Pediatr Crit Care Med. 2017 Oct;18(10):1003-1005. PubMed PMID: 28976472
• McIntosh AM, Tong S, Deakyne SJ, Davidson JA, Scott HF. Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis. Pediatr Crit Care Med. 2017 Aug;18(8):750-757. PubMed PMID: 28486385
• Benjamin Steven Frank, Tracy T Urban, Suhong Tong, Courtney Cassidy, Max B Mitchell, Christopher S Nichols and Jesse A Davidson. Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair. World Journal of Cardiology; (In Press).
• Jessica N. Persson, Christine H. Baird, Suhong Tong, Tracy T Urban, Jelena Klawitter, Paul E. Wischmeyer, and Jesse A. Davidson. Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity. Ped. Res. 2017; (In Press)
• Aschner Y, Davidson JA. Early Plasma Matrix Metalloproteinase Profiles Offer New Insight into the Biology and Prognosis of Pediatric Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2018 Aug 30. [Epub ahead of print] PubMed PMID: 30160977
• Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia after Infant Cardiothoracic Surgery. Shock. 2018 Apr 16. [Epub ahead of print] PubMed PMID: 29664834
• Jesse A. Davidson, Zachary Pfeifer, Benjamin Frank, Suhong Tong, Tracy T. Urban, Paul A. Wischmeyer, Peter Mourani, Bruce Landeck, Uwe Christians, Jelena Klawitter. Metabolomic fingerprinting of infants undergoing cardiopulmonary bypass: changes in metabolic pathways and association with mortality and cardiac intensive care unit length of stay. Journal of the American Heart Association. Accepted 11/2018
• Davidson JA, Khailova L, Treece A, Robison J, Soranno DE, Jaggers J, Ing RJ, Lawson S, Lujan SO. Alkaline Phosphatase Treatment of Acute Kidney Injury in an Infant Piglet Model of Cardiopulmonary Bypass with Deep Hypothermic Circulatory Arrest. Sci Rep. 2019 Oct 2;9(1):14175. PubMed PMID: 31578351
• Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia After Infant Cardiothoracic Surgery. Shock. 2019 Mar;51(3):328-336. PubMed PMID: 29664834
• Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA. Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta. Congenit Heart Dis. 2019 May;14(3):446-453. PubMed PMID: 30650250
• Aschner Y, Davidson JA. Early Plasma Matrix Metalloproteinase Profiles Offer New Insight into the Biology and Prognosis of Pediatric Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2019 Jan 15;199(2):134-136. PubMed PMID: 30160977
• Davidson JA, Pfeifer Z, Frank B, Tong S, Urban TT, Wischmeyer PA, Mourani P, Landeck B, Christians U, Klawitter J. Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay. J Am Heart Assoc. 2018 Dec 18;7(24):e010711. PubMed PMID: 30561257
• Watson JD, Urban TT, Tong SS, Zenge J, Khailova L, Wischmeyer PE, Davidson JA. Immediate Post-operative Enterocyte Injury, as Determined by Increased Circulating Intestinal Fatty Acid Binding Protein, Is Associated With Subsequent Development of Necrotizing Enterocolitis After Infant Cardiothoracic Surgery. Front Pediatr. 2020;8:267. PubMed PMID: 32537446
• Czaja AS, Collins K, Valuck RJ, Anderson HD, Ghosh D, Davidson JA. Validity of administrative claims-based algorithms for ventricular arrhythmia and cardiac arrest in the pediatric population. Pharmacoepidemiol Drug Saf. 2020 Nov;29(11):1499-1503. PubMed PMID: 32283564
• Khailova L, Robison J, Jaggers J, Ing R, Lawson S, Treece A, Soranno D, Osorio Lujan S, Davidson JA. Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest. J Inflamm (Lond). 2020;17:27. PubMed PMID: 32817746
• Czaja AS, Anderson HD, Ghosh D, Davidson J, Campbell JD, Valuck RJ. Increased Odds of Ventricular Arrhythmias Associated with Selective Serotonin Reuptake Inhibitor Use among the Pediatric and Young Adult Population: A Case-Control Study. J Pediatr. 2020 Jul 6. [Epub ahead of print] PubMed PMID: 32645405
• Sabapathy D, Klawitter J, Silveira L, Khailova L, Mitchell MB, Morgan GJ, DiMaria MV, Twite M, Frank BS, Davidson JA. Activation of kynurenine pathway of tryptophan metabolism after infant cardiac surgery with cardiopulmonary bypass: a prospective cohort study. Metabolomics. 2020 Sep 5;16(9):93. PubMed PMID: 32889608
• Frank BS, Khailova L, Silveira L, Mitchell MB, Morgan GJ, Hsieh EWY, DiMaria MV, Twite M, Klawitter J, Davidson JA. Proteomic profiling identifies key differences between inter-stage infants with single ventricle heart disease and healthy controls. Transl Res. 2020 Oct 9. [Epub ahead of print] PubMed PMID: 33045409
• Evan Pagano, Benjamin Frank, James Jaggers, Mark Twite, Tracy T. Urban, Jelena Klawitter, Jesse Davidson. Alterations in Metabolites Associated with Hypoxemia in Neonates and Infants with Congenital Heart Disease. Congenital Heart Disease Sep 2020;15(4):251-265
• Frank BS, Schäfer M, Douwes JM, Ivy DD, Abman SH, Davidson JA, Burzlaff S, Mitchell MB, Morgan GJ, Browne LP, Barker AJ, Truong U, von Alvensleben JC. Novel measures of left ventricular electromechanical discoordination predict clinical outcomes in children with pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2020 Feb 1;318(2):H401-H412. PubMed PMID: 31858817
• Watson JD, Davidson JA. The Microbiome is a Welcome Addition to the Growing "Omes" of Cardiopulmonary Bypass in Congenital Heart Disease Surgery. JACC Basic Transl Sci. 2021 Apr;6(4):328-330. PubMed PMID: 33999038
• Sperotto F, Davidson JA, Smith-Parrish MN, Elhoff JJ, Sinha A, Blinder JJ, Ehrmann DE, Marino BS, Kheir JN. Development of Care Curves Following the Stage 1 Palliation: A Comparison of Intensive Care Among 5 Centers. J Am Heart Assoc. 2021 Jun;10(11):e019396. PubMed PMID: 34013742
• Persson JN, Holstein J, Silveira L, Irons A, Rajab TK, Jaggers J, Twite MD, Scahill C, Kohn M, Gold C, Davidson JA. Validation of Point-of-Care Ultrasound to Measure Perioperative Edema in Infants With Congenital Heart Disease. Front Pediatr. 2021;9:727571. PubMed PMID: 34497787
• Cooney SJ, Klawitter J, Khailova L, Robison J, Jaggers J, Ing RJ, Lawson S, Frank BS, Lujan SO, Davidson JA. Regional lung metabolic profile in a piglet model of cardiopulmonary bypass with circulatory arrest. Metabolomics. 2021 Sep 22;17(10):89. PubMed PMID: 34553313
• Davidson JA, Frank BS, Urban TT, Twite M, Jaggers J, Khailova L, Klawitter J. Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass. Pediatr Nephrol. 2021 Oct;36(10):3259-3269. PubMed PMID: 33954809
• Frank BS, Khailova L, Silveira L, Mitchell MB, Morgan GJ, DiMaria MV, Davidson JA. Increased Circulating Endothelin 1 Is Associated With Postoperative Hypoxemia in Infants With Single-Ventricle Heart Disease Undergoing Superior Cavopulmonary Anastomosis. J Am Heart Assoc. 2022 Mar 15;11(6):e024007. PubMed PMID: 35243904
• Davidson JA, Robison J, Khailova L, Frank BS, Jaggers J, Ing RJ, Lawson S, Iguidbashian J, Ali E, Treece A, Soranno DE, Osorio-Lujan S, Klawitter J. Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury. Am J Physiol Renal Physiol. 2022 Jul 1;323(1):F20-F32. PubMed PMID: 35532069
• Iguidbashian KG, Robison J, Khailova L, Jaggers J, Ing R, Lawson S, Osorio Lujan SM, Klawitter J, Davidson JA. Changes in infant porcine pulmonary tissue oxylipins induced by cardiopulmonary bypass. Pediatr Res. 2022 Nov;92(5):1274-1281. PubMed PMID: 35681098
• Salomon JD, Qiu H, Feng D, Owens J, Khailova L, Lujan SO, Iguidbashian J, Chhonker YS, Murry DJ, Riethoven JJ, Lindsey ML, Singh AB, Davidson JA. Piglet cardiopulmonary bypass induces intestinal dysbiosis and barrier dysfunction associated with systemic inflammation. Dis Model Mech. 2022 Nov 25. [Epub ahead of print] PubMed PMID: 36426663
• Benjamin S. Frank, Ludmila Khailova, Jonathan Dekermanjian, Max B. Mitchell, Gareth J. Morgan, Mark Twite, Uwe Christians, Michael V. DiMaria, Jelena Klawitter, Jesse A. Davidson. Interstage Single Ventricle Heart Disease Infants Show Dysregulation In Multiple Metabolic Pathways: Targeted Metabolomics Analysis. JACC-Advances, 2022 (In press)
• Ali EA, Syed A, Khailova L, Iguidbashian JP, Suarez-Pierre A, Klawitter J, Stone M, Mancuso CA, Frank BS, Davidson JA. Novel Biomarkers of Necrotizing Enterocolitis in Neonates Undergoing Congenital Heart Disease Surgery: A Pilot Cohort Study. J Am Heart Assoc. 2023 Aug;12(15):e030712. PubMed PMID: 37489765
• Wolfe KR, Caprarola SD, Clark C, Davidson J, Everitt MD, Faul L, Hageman C, Kelly SL, Maloney E, Patteson H, Scott S, Talbot A, Tong S, DiMaria KL. Implementation of the Cardiac Inpatient Neurodevelopmental Care Optimization (CINCO) programme: an interdisciplinary, generalisable approach to inpatient neurodevelopmental care. Cardiol Young. 2023 Apr 12;:1-8. [Epub ahead of print] PubMed PMID: 37042605
• Frank BS, Khailova L, Dekermanjian J, Mitchell MB, Morgan GJ, Twite M, Christians U, DiMaria MV, Klawitter J, Davidson JA. Interstage Single Ventricle Heart Disease Infants Show Dysregulation in Multiple Metabolic Pathways: Targeted Metabolomics Analysis. JACC Adv. 2023 Jan;2(1). PubMed PMID: 36875009
• Salomon JD, Qiu H, Feng D, Owens J, Khailova L, Osorio Lujan S, Iguidbashian J, Chhonker YS, Murry DJ, Riethoven JJ, Lindsey ML, Singh AB, Davidson JA. Piglet cardiopulmonary bypass induces intestinal dysbiosis and barrier dysfunction associated with systemic inflammation. Dis Model Mech. 2023 May 1;16(5). PubMed PMID: 36426663
• Frank BS, Nandy D, Khailova L, Mitchell MB, Morgan GJ, Twite M, DiMaria MV, Davidson JA. Circulating biomarkers of extracellular matrix dysregulation are associated with adverse post-stage 2 outcomes in infants with single ventricle heart disease. Sci Rep. 2023 Sep 28;13(1):16318. PubMed PMID: 37770592
• Lindsay Marie Thomson, Christopher Mancuso, Kelly R. Wolfe, Lida Khailova, Sierra Niemiec, Eiman Ali, Michael Di Maria, Max Mitchell, Mark Twite, Gareth Morgan, Benjamin Frank and Jesse Davidson. The Proteomic Fingerprint in Infants with Single Ventricle Heart Disease in the Interstage Period: Evidence of Chronic Inflammation and Widespread Activation of Biological Networks. Frontiers in Pediatrics (In press)
• Davidson, Jesse; Thomson, Lindsay; Frank, Benjamin. Omics approaches to mechanistic, biomarker, and therapeutic development for right ventricular failure in congenital right-sided obstructive lesions: a brave new world? World Journal for Pediatric and Congenital Heart Surgery (In Press)
• Wolfe KR, Thomson LM, Niemiec S, Mancuso CA, Khailova L, Frank BS, Davidson JA. Early Circulating Biomarkers of Language Development in Single Ventricle Heart Disease. JAMA Pediatr. 2024 Oct 1;178(10):1072-1074. PubMed PMID: 39102258
• Thomson LM, Niemiec S, Mancuso CA, Khailova L, Ali E, Syed A, Wolfe KR, Zakrzewski J, Stone M, Hyslop R, Frank BS, Davidson JA. Disruption of the Circulating Proteome in Neonates Receiving Extracorporeal Membrane Oxygenation Following Congenital Heart Disease Surgery: A Nested Case-Control Study. J Pediatr. 2024 Sep 19;276:114322. [Epub ahead of print] PubMed PMID: 39306320
• Frank BS, Niemiec S, Khailova L, Mancuso CA, Lehmann T, Mitchell MB, Morgan GJ, Twite M, DiMaria MV, Klawitter J, Davidson JA. Arginine-NO metabolites are associated with morbidity in single ventricle infants undergoing stage 2 palliation. Pediatr Res. 2024 Jul;96(2):347-355. PubMed PMID: 38565916
• Davidson JA, Thomson LM, Frank BS. Invited Commentary: Omics Approaches to Mechanistic, Biomarker, and Therapeutic Development for Right Ventricular Failure in Congenital Right-Sided Obstructive Lesions: A Brave New World?. World J Pediatr Congenit Heart Surg. 2024 Mar;15(2):174-176. PubMed PMID: 38478369
• Owens J, Qiu H, Knoblich C, Gerjevic L, Izard J, Xu L, Lee J, Kollala SS, Murry DJ, Riethoven JJ, Davidson JA, Singh AB, Ibrahimiye A, Ortmann L, Salomon JD. Feeding intolerance after pediatric cardiac surgery is associated with dysbiosis, barrier dysfunction, and reduced short-chain fatty acids. Am J Physiol Gastrointest Liver Physiol. 2024 Nov 1;327(5):G685-G696. PubMed PMID: 39224072
• Davidson JA, Urban T, Tong S, Twite M, Woodruff A, Wischmeyer PE, Klawitter J. Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass. PLoS One. 2016 Jul 6;11(7):e0158981. PubMed PMID: 27384524
• Frank B, Davidson J, Tong S, Martin B, Heizer H, Anderson MS, Glode MP, Dominguez SR, Jone PN. Myocardial Strain and Strain Rate in Kawasaki Disease: Range, Recovery, and Relationship to Systemic Inflammation/Coronary Artery Dilation. J Clin Exp Cardiolog. 2016 Apr;7(4). PubMed PMID: 27182455

Professional Memberships

• American Heart Associaton, Member
• Society of Critical Care Medicine, Member
• Pediatric Cardiac Intensive Care Society, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• Children's Hospital Colorado
• University of Colorado Hospital

Specialty Information

Specialties

• Pediatrics, Board Certification (2007, 2007)
• Pediatric Cardiology, Board Certification (2013)
• Pediatric Critical Care Medicine, Board Certification (2013)

Conditions & Treatments

• Critical Care
• Heart and Circulation - Congenital Heart Disease
• Heart and Circulation