Andy Mengshol, MD
Sr. Instructor, Medicine-Gastroenterology

Medical School:
  • MD, Dartmouth Medical School (2003)
Graduate School :
  • PhD, Dartmouth Medical School (2001)
Undergraduate School:
  • BS, University of California–Davis (CA) (1993)
  • University of Colorado (2004)
  • University of Colorado, Internal Medicine (2006)
  • University of Colorado, Gastroenterology (2009)
Languages: English
Department: Medicine-Gastroenterology

Professional Titles

  • Gastroenterology Practice Director Highlands Ranch Hospital


  • Senior Instructor (2019)
    School of Medicine, Medicine
    Gastroenterology and Hepatology


  • Harwood NM, Golden-Mason L, Cheng L, Rosen HR, Mengshol JA. HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production. J Leukoc Biol. 2016 Mar;99(3):495-503. PubMed PMID: 26475932
  • Chan MM, Chan MM, Mengshol JA, Fish DN, Chan ED. Octreotide: a drug often used in the critical care setting but not well understood. Chest. 2013 Dec;144(6):1937-1945. PubMed PMID: 24297127
  • Mengshol JA, Golden-Mason L, Castelblanco N, Im KA, Dillon SM, Wilson CC, Rosen HR. Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes. Gut. 2009 Jul;58(7):964-73. PubMed PMID: 19193669
  • Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol. 2007 Sep;81(17):9249-58. PubMed PMID: 17567698
  • Mengshol JA, Golden-Mason L, Rosen HR. Mechanisms of Disease: HCV-induced liver injury. Nat Clin Pract Gastroenterol Hepatol. 2007 Nov;4(11):622-34. PubMed PMID: 17978819
  • Mengshol JA, Mix KS, Brinckerhoff CE. Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?. Arthritis Rheum. 2002 Jan;46(1):13-20. PubMed PMID: 11817584
  • Mengshol JA, Vincenti MP, Brinckerhoff CE. IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways. Nucleic Acids Res. 2001 Nov 1;29(21):4361-72. PubMed PMID: 11691923
  • Mix KS, Mengshol JA, Benbow U, Vincenti MP, Sporn MB, Brinckerhoff CE. A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines. Arthritis Rheum. 2001 May;44(5):1096-104. PubMed PMID: 11352241
  • Mengshol JA, Vincenti MP, Coon CI, Barchowsky A, Brinckerhoff CE. Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. Arthritis Rheum. 2000 Apr;43(4):801-11. PubMed PMID: 10765924
  • Vincenti MP, Coon CI, Mengshol JA, Yocum S, Mitchell P, Brinckerhoff CE. Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: differential expression with collagenase-1 (matrix metalloproteinase-1). Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):341-6. PubMed PMID: 9512498
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Professional Memberships

  • Crohn's and Colitis Foundation, Member
  • American College of Gastroenterology, Member
  • American Gastroenterological Association, Member

Practice Locations

UCHealth Gastroenterology Clinic - Lone Tree
9548 Park Meadows Drive
Lone Tree, CO 80124

UCHealth Surgical Care - Highlands Ranch Hospital
1500 Park Central Drive
Highlands Ranch, CO 80129

Hospital Affiliation
  • University of Colorado Hospital
  • UCHealth Highlands Ranch Hospital

Specialty Information

  • Gastroenterology, Board Certification (2009)
Conditions & Treatments
  • Digestive System
  • Digestive System - Celiac Disease
  • Digestive System - Colonoscopy
  • Digestive System - Gastroenterology (Stomach, Bowel, General GI Problems)
  • Digestive System - Gastroesophageal Reflux
  • Digestive System - Hepatology (Liver Disorders)
  • Digestive System - Inflammatory Bowel Disease (IBD): Crohn’s disease, ulcerative colitis, microscopic colitis
  • Digestive System - Irritable Bowel Syndrome (IBS)
Care Philosophy
I feel that effective communication with my patients and referring providers is critical; my goal is to provide compassionate, cutting edge care to my patients.

Personal Interests
My family and I enjoy the outdoors including skiing, cycling, and hiking.

Public Speaking

General Information

Medical Schools:
  • MD, Dartmouth Medical School (2003)
Graduate Schools:
  • PhD, Dartmouth Medical School (2001)
Undergraduate Schools:
  • BS, University of California–Davis (CA) (1993)
  • University of Colorado (2004)
Residency Programs:
  • University of Colorado, Internal Medicine (2006)
  • University of Colorado, Gastroenterology (2009)
Languages: English
Department: Medicine-Gastroenterology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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