Andy Mengshol, MD
Sr. Instructor, Medicine-Gastroenterology

Medical School:
  • MD, Dartmouth Medical School (2003)
Graduate School :
  • PhD, Dartmouth Medical School (2001)
Undergraduate School:
  • BS, University of California–Davis (CA) (1993)
  • University of Colorado (2004)
  • University of Colorado, Internal Medicine (2006)
  • University of Colorado, Gastroenterology (2009)
Languages: English
Department: Medicine-Gastroenterology

Professional Titles

  • Gastroenterology Practice Director Highlands Ranch Hospital


  • Senior Instructor (2019)
    School of Medicine, Medicine
    Gastroenterology and Hepatology


  • Robertson DJ, Dominitz JA, Beed A, Boardman KD, Del Curto BJ, Guarino PD, Imperiale TF, LaCasse A, Larson MF, Gupta S, Lieberman D, Planeta B, Shaukat A, Sultan S, Menees SB, Saini SD, Schoenfeld P, Goebel S, von Rosenvinge EC, Baffy G, Halasz I, Pedrosa MC, Kahng LS, Cassim R, Greer KB, Kinnard MF, Bhatt DB, Dunbar KB, Harford WV Jr, Mengshol JA, Olson JE, Patel SG, Antaki F, Fisher DA, Sullivan BA, Lenza C, Prajapati DN, Wong H, Beyth R, Lieb JG 2nd, Manlolo J, Ona FV, Cole RA, Khalaf N, Kahi CJ, Kohli DR, Rai T, Sharma P, Anastasiou J, Hagedorn C, Fernando RS, Jackson CS, Jamal MM, Lee RH, Merchant F, May FP, Pisegna JR, Omer E, Parajuli D, Said A, Nguyen TD, Tombazzi CR, Feldman PA, Jacob L, Koppelman RN, Lehenbauer KP, Desai DS, Madhoun MF, Tierney WM, Ho MQ, Hockman HJ, Lopez C, Carter Paulson E, Tobi M, Pinillos HL, Young M, Ho NC, Mascarenhas R, Promrat K, Mutha PR, Pandak WM Jr, Shah T, Schubert M, Pancotto FS, Gawron AJ, Underwood AE, Ho SB, Magno-Pagatzaurtundua P, Toro DH, Beymer CH, Kaz AM, Elwing J, Gill JA, Goldsmith SF, Yao MD, Protiva P, Pohl H, Kyriakides T. Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial. JAMA Netw Open. 2023 Jul 3;6(7):e2321730. PubMed PMID: 37432690
  • Harwood NM, Golden-Mason L, Cheng L, Rosen HR, Mengshol JA. HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production. J Leukoc Biol. 2016 Mar;99(3):495-503. PubMed PMID: 26475932
  • Chan MM, Chan MM, Mengshol JA, Fish DN, Chan ED. Octreotide: a drug often used in the critical care setting but not well understood. Chest. 2013 Dec;144(6):1937-1945. PubMed PMID: 24297127
  • Mengshol JA, Golden-Mason L, Castelblanco N, Im KA, Dillon SM, Wilson CC, Rosen HR. Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes. Gut. 2009 Jul;58(7):964-73. PubMed PMID: 19193669
  • Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol. 2007 Sep;81(17):9249-58. PubMed PMID: 17567698
  • Mengshol JA, Golden-Mason L, Rosen HR. Mechanisms of Disease: HCV-induced liver injury. Nat Clin Pract Gastroenterol Hepatol. 2007 Nov;4(11):622-34. PubMed PMID: 17978819
  • Mengshol JA, Mix KS, Brinckerhoff CE. Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?. Arthritis Rheum. 2002 Jan;46(1):13-20. PubMed PMID: 11817584
  • Mengshol JA, Vincenti MP, Brinckerhoff CE. IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways. Nucleic Acids Res. 2001 Nov 1;29(21):4361-72. PubMed PMID: 11691923
  • Mix KS, Mengshol JA, Benbow U, Vincenti MP, Sporn MB, Brinckerhoff CE. A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines. Arthritis Rheum. 2001 May;44(5):1096-104. PubMed PMID: 11352241
  • Mengshol JA, Vincenti MP, Coon CI, Barchowsky A, Brinckerhoff CE. Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. Arthritis Rheum. 2000 Apr;43(4):801-11. PubMed PMID: 10765924
  • Vincenti MP, Coon CI, Mengshol JA, Yocum S, Mitchell P, Brinckerhoff CE. Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: differential expression with collagenase-1 (matrix metalloproteinase-1). Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):341-6. PubMed PMID: 9512498
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Professional Memberships

  • Crohn's and Colitis Foundation, Member
  • American College of Gastroenterology, Member
  • American Gastroenterological Association, Member

Practice Locations

UCHealth Gastroenterology Clinic - Lone Tree
9548 Park Meadows Drive
Lone Tree, CO 80124

UCHealth Surgical Care - Highlands Ranch Hospital
1500 Park Central Drive
Highlands Ranch, CO 80129

Hospital Affiliation
  • University of Colorado Hospital
  • UCHealth Highlands Ranch Hospital

Specialty Information

  • Gastroenterology, Board Certification (2009)
Conditions & Treatments
  • Digestive System
  • Digestive System - Celiac Disease
  • Digestive System - Colonoscopy
  • Digestive System - Gastroenterology (Stomach, Bowel, General GI Problems)
  • Digestive System - Gastroesophageal Reflux
  • Digestive System - Hepatology (Liver Disorders)
  • Digestive System - Inflammatory Bowel Disease (IBD): Crohn’s disease, ulcerative colitis, microscopic colitis
  • Digestive System - Irritable Bowel Syndrome (IBS)
Care Philosophy
I feel that effective communication with my patients and referring providers is critical; my goal is to provide compassionate, cutting edge care to my patients.

Personal Interests
My family and I enjoy the outdoors including skiing, cycling, and hiking.

Public Speaking

General Information

Medical Schools:
  • MD, Dartmouth Medical School (2003)
Graduate Schools:
  • PhD, Dartmouth Medical School (2001)
Undergraduate Schools:
  • BS, University of California–Davis (CA) (1993)
  • University of Colorado (2004)
Residency Programs:
  • University of Colorado, Internal Medicine (2006)
  • University of Colorado, Gastroenterology (2009)
Languages: English
Department: Medicine-Gastroenterology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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