Peter Mourani, MD

Professional Titles

• Director, Clinical Research
• Medical Director, Children's Hospital Colorado Research Institute

Recognitions

• Denver Top Doctor, 5280 Magazine (2011)
  
• Denver Top Doctor, 5280 Magazine (2010)
  
• Denver Top Doctor, 5280 Magazine (2009)
• Denver Top Doctor, 5280 Magazine (2012)
• Denver Top Doctor, 5280 Magazine (2013)
• Denver Top Doctor, 5280 Magazine (2014)
• Denver Top Doctor, 5280 Magazine (2015)
• Denver Top Doctor, 5280 Magazine (2016)
• Denver Top Doctor, 5280 Magazine (2017)

Research Interests

My research interests are primarily focused on investigating mechanisms of lung and lung blood vessel growth and injury in prematurely born infants. My research projects in this area explore prenatal and postnatal risk factors for impaired lung blood vessel growth and development of chronic lung disease, including pulmonary hypertension, in these infants. I am also investigating predictors of chronic lung disease and more sensitive measures to detect and measure disease severity. Additionally, I conduct NIH funded research projects utilizing molecular microbiome, transcriptomic, and proteomic analysis to investigate the contribution of different bacteria to ventilator associated pneumonia to facilitate improved prevention and treatment methods.

Publications

• Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-Dimer, and Risk of Poor Neurologic Outcome in Childhood-Onset Arterial Ischemic Stroke. J Pediatr. 2012 Dec 19. [Epub ahead of print] PubMed PMID: 23260102
• Hancock HS, Wang M, Gist KM, Gibson E, Miyamoto SD, Mourani PM, Manco-Johnson MJ, Goldenberg NA. Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study. Cardiol Young. 2012 Oct 22;:1-9. [Epub ahead of print] PubMed PMID: 23088931
• Manco-Johnson MJ, Wang M, Goldenberg NA, Soep J, Gibson E, Knoll CM, Mourani PM. Treatment, survival, and thromboembolic outcomes of thrombotic storm in children. J Pediatr. 2012 Oct;161(4):682-8.e1. PubMed PMID: 22578585
• Baker CD, Balasubramaniam V, Mourani PM, Sontag MK, Black CP, Ryan SL, Abman SH. Cord blood angiogenic progenitor cells are decreased in bronchopulmonary dysplasia. Eur Respir J. 2012 Dec;40(6):1516-22. PubMed PMID: 22496315
• Branchford BR, Mourani P, Bajaj L, Manco-Johnson M, Wang M, Goldenberg NA. Risk factors for in-hospital venous thromboembolism in children: a case-control study employing diagnostic validation. Haematologica. 2012 Apr;97(4):509-15. PubMed PMID: 22133768
• Cooper L, Moore C, Branchford B, Greffe B, Capocelli K, Kuder A, Mehta I, Mourani PM. Successful pulmonary artery embolectomy in a patient with a saddle Wilms tumor embolus. Pediatr Blood Cancer. 2012 May;58(5):806-9. PubMed PMID: 21681933
• Ambalavanan N, Mourani P. Pulmonary hypertension in bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol. 2014 Mar 10. [Epub ahead of print] PubMed PMID: 24616323
• Mourani PM, Kinsella JP, Clermont G, Kong L, Perkins AM, Weissfeld L, Cutter G, Linde-Zwirble WT, Abman SH, Angus DC, Watson RS, Prolonged Outcomes after Nitric Oxide (PrONOx) Investigators. Intensive Care Unit Readmission during Childhood after Preterm Birth with Respiratory Failure. J Pediatr. 2013 Dec 31. [Epub ahead of print] PubMed PMID: 24388320
• Eggleston HA, Gunville CF, Miller JI, Sontag MK, Mourani PM. A comparison of characteristics and outcomes in severe human metapneumovirus and respiratory syncytial virus infections in children treated in an intensive care unit. Pediatr Infect Dis J. 2013 Dec;32(12):1330-4. PubMed PMID: 23811741
• Gunville CF, Mourani PM, Ginde AA. The role of vitamin D in prevention and treatment of infection. Inflamm Allergy Drug Targets. 2013 Aug;12(4):239-45. PubMed PMID: 23782205
• Mourani PM, Abman SH. Pulmonary vascular disease in bronchopulmonary dysplasia: pulmonary hypertension and beyond. Curr Opin Pediatr. 2013 Jun;25(3):329-37. PubMed PMID: 23615175
• Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke. J Pediatr. 2013 May;162(5):1041-6.e1. PubMed PMID: 23260102
• Hancock HS, Wang M, Gist KM, Gibson E, Miyamoto SD, Mourani PM, Manco-Johnson MJ, Goldenberg NA. Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study. Cardiol Young. 2013 Jun;23(3):344-52. PubMed PMID: 23088931
• Ferdinands JM, Olsho LEW, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG on behalf of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. J Infect Dis. In press.
• Abman SH, Baker C, Gien J, Mourani P, Galambos C. The Robyn Barst Memorial Lecture: Differences between the fetal, newborn, and adult pulmonary circulations: relevance for age-specific therapies (2013 Grover Conference series). Pulm Circ. 2014 Sep;4(3):424-40. PubMed PMID: 25621156
• Davis SM, Maddux AB, Alonso GT, Okada CR, Mourani PM, Maahs DM. Profound hypokalemia associated with severe diabetic ketoacidosis. Pediatr Diabetes. 2014 Nov 27. [Epub ahead of print] PubMed PMID: 25430801
• Mourani PM, Sontag MK, Younoszai A, Miller JI, Kinsella JP, Baker CD, Poindexter BB, Ingram DA, Abman SH. Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2015 Jan 1;191(1):87-95. PubMed PMID: 25389562
• Ferdinands JM, Olsho LE, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. J Infect Dis. 2014 Sep 1;210(5):674-83. PubMed PMID: 24676207
• Baker CD, Abman SH, Mourani PM. Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia. Pediatr Allergy Immunol Pulmonol. 2014 Mar 1;27(1):8-16. PubMed PMID: 24669351
• Ambalavanan N, Mourani P. Pulmonary hypertension in bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol. 2014 Mar;100(3):240-6. PubMed PMID: 24616323
• Mourani PM, Kinsella JP, Clermont G, Kong L, Perkins AM, Weissfeld L, Cutter G, Linde-Zwirble WT, Abman SH, Angus DC, Watson RS, Prolonged Outcomes after Nitric Oxide (PrONOx) Investigators. Intensive care unit readmission during childhood after preterm birth with respiratory failure. J Pediatr. 2014 Apr;164(4):749-755.e3. PubMed PMID: 24388320
• Mourani PM, Abman SH. Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia. Clin Perinatol. 2015 Dec;42(4):839-55. PubMed PMID: 26593082
• Abman SH, Mourani P, Wagner B. Genomic Insights into Respiratory Outcomes after Preterm Birth. Am J Respir Crit Care Med. 2015 Sep 1;192(5):530-2. PubMed PMID: 26325151
• Di Maria MV, Younoszai AK, Sontag MK, Miller JI, Poindexter BB, Ingram DA, Abman SH, Mourani PM. Maturational Changes in Diastolic Longitudinal Myocardial Velocity in Preterm Infants. J Am Soc Echocardiogr. 2015 Sep;28(9):1045-52. PubMed PMID: 26025727
• Davis SM, Maddux AB, Alonso GT, Okada CR, Mourani PM, Maahs DM. Profound hypokalemia associated with severe diabetic ketoacidosis. Pediatr Diabetes. 2016 Feb;17(1):61-5. PubMed PMID: 25430801
• Mourani PM, Sontag MK, Younoszai A, Miller JI, Kinsella JP, Baker CD, Poindexter BB, Ingram DA, Abman SH. Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2015 Jan 1;191(1):87-95. PubMed PMID: 25389562
• Lynch AM, Wagner BD, Mandava N, Palestine AG, Mourani PM, McCourt EA, Oliver SC, Abman SH. The Relationship of Novel Plasma Proteins in the Early Neonatal Period With Retinopathy of Prematurity. Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):5076-5082. PubMed PMID: 27679852
• Goldenberg NA, Daniels SR, Mourani PM, Hamblin F, Stowe A, Powell S, Ford DE, Ellen J. Enhanced Infrastructure for Optimizing the Design and Execution of Clinical Trials and Longitudinal Cohort Studies in the Era of Precision Medicine. J Pediatr. 2016 Apr;171:300-6.e1-2. PubMed PMID: 26787376
• Mourani PM, Abman SH. Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia. Clin Perinatol. 2015 Dec;42(4):839-55. PubMed PMID: 26593082
• Abman SH, Mourani P, Wagner B. Genomic Insights into Respiratory Outcomes after Preterm Birth. Am J Respir Crit Care Med. 2015 Sep 1;192(5):530-2. PubMed PMID: 26325151
• Di Maria MV, Younoszai AK, Sontag MK, Miller JI, Poindexter BB, Ingram DA, Abman SH, Mourani PM. Maturational Changes in Diastolic Longitudinal Myocardial Velocity in Preterm Infants. J Am Soc Echocardiogr. 2015 Sep;28(9):1045-52. PubMed PMID: 26025727
• Davis SM, Maddux AB, Alonso GT, Okada CR, Mourani PM, Maahs DM. Profound hypokalemia associated with severe diabetic ketoacidosis. Pediatr Diabetes. 2016 Feb;17(1):61-5. PubMed PMID: 25430801
• Mourani PM, Sontag MK, Younoszai A, Miller JI, Kinsella JP, Baker CD, Poindexter BB, Ingram DA, Abman SH. Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2015 Jan 1;191(1):87-95. PubMed PMID: 25389562
• Maddux AB, DeWitt PE, Mourani PM, Bennett TD. Hospital Readmissions After Pediatric Trauma. Pediatr Crit Care Med. 2017 Nov 28. [Epub ahead of print] PubMed PMID: 29210926
• Langelier C, White CV, Sontag MK, Mourani PM, DeRisi JL. Complete Genome Sequence of a Divergent Human Rhinovirus C Isolate from an Infant with Severe Community-Acquired Pneumonia in Colorado, USA. Genome Announc. 2017 Nov 30;5(48). PubMed PMID: 29192071
• Wagner BD, Sontag MK, Harris JK, Miller JI, Morrow L, Robertson CE, Stephens MJ, Poindexter BB, Abman SH, Mourani PM. Prenatal complications are associated with the postnatal airway host response and microbiota in intubated preterm infants. J Matern Fetal Neonatal Med. 2017 Nov 28;:1-8. [Epub ahead of print] PubMed PMID: 29157044
• Abman SH, Mourani P, Wagner B. Reply to: Is It Adequate to Assess Prenatal Smoking Risk to Infants Without Considering Socioeconomic Status?. Am J Respir Crit Care Med. 2017 Nov 7. [Epub ahead of print] PubMed PMID: 29111777
• Mourani PM, Sontag MK. Ventilator-Associated Pneumonia in Critically Ill Children: A New Paradigm. Pediatr Clin North Am. 2017 Oct;64(5):1039-1056. PubMed PMID: 28941534
• Goss KN, Everett AD, Mourani PM, Baker CD, Abman SH. Addressing the challenges of phenotyping pediatric pulmonary vascular disease. Pulm Circ. 2017 Mar;7(1):7-19. PubMed PMID: 28680562
• Wagner BD, Babinec AE, Carpenter C, Gonzalez S, O'Brien G, Rollock K, Williamson K, Mourani PM, Abman S. Proteomic Profiles Associated with Early Echocardiogram Evidence of Pulmonary Vascular Disease in Preterm Infants. Am J Respir Crit Care Med. 2017 Jun 26. [Epub ahead of print] PubMed PMID: 28650220
• Ladd AK, Skillman HE, Haemer MA, Mourani PM. Preventing Underfeeding and Overfeeding: A Clinician's Guide to the Acquisition and Implementation of Indirect Calorimetry. Nutr Clin Pract. 2017 May 1;:884533617710214. [Epub ahead of print] PubMed PMID: 28549221
• Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG. Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection. J Infect Dis. 2017 Jul 1;216(1):14-21. PubMed PMID: 28531322
• Morrow LA, Wagner BD, Ingram DA, Poindexter BB, Schibler K, Cotten CM, Dagle J, Sontag MK, Mourani PM, Abman SH. Antenatal Determinants of Bronchopulmonary Dysplasia and Late Respiratory Disease in Preterm Infants. Am J Respir Crit Care Med. 2017 Aug 1;196(3):364-374. PubMed PMID: 28249118
• Carlton EF, Sontag MK, Younoszai A, DiMaria MV, Miller JI, Poindexter BB, Abman SH, Mourani PM. Reliability of Echocardiographic Indicators of Pulmonary Vascular Disease in Preterm Infants at Risk for Bronchopulmonary Dysplasia. J Pediatr. 2017 Jul;186:29-33. PubMed PMID: 28411949
• Wagner BD, Sontag MK, Harris JK, Miller JI, Morrow L, Robertson CE, Stephens M, Poindexter BB, Abman SH, Mourani PM. Airway Microbial Community Turnover Differs by BPD Severity in Ventilated Preterm Infants. PLoS One. 2017;12(1):e0170120. PubMed PMID: 28129336
• Davidson JA, Pfeifer Z, Frank B, Tong S, Urban TT, Wischmeyer PA, Mourani P, Landeck B, Christians U, Klawitter J. Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay. J Am Heart Assoc. 2018 Dec 18;7(24):e010711. PubMed PMID: 30561257
• Zuppa AF, Zane NR, Moorthy G, Dalton HJ, Abraham A, Reeder RW, Carcillo JA, Yates AR, Meert KL, Berg RA, Sapru A, Mourani P, Notterman DA, Dean JM, Gastonguay MR. A Population Pharmacokinetic Analysis to Study the Effect of Extracorporeal Membrane Oxygenation on Cefepime Disposition in Children. Pediatr Crit Care Med. 2019 Jan;20(1):62-70. PubMed PMID: 30431557
• Barhight MF, Brinton J, Stidham T, Soranno DE, Faubel S, Griffin BR, Goebel J, Mourani PM, Gist KM. Increase in chloride from baseline is independently associated with mortality in critically ill children. Intensive Care Med. 2018 Dec;44(12):2183-2191. PubMed PMID: 30382307
• Mourani PM, Mandell EW, Meier M, Younoszai A, Brinton JT, Wagner BD, Arjaans S, Poindexter BB, Abman SH. Early Pulmonary Vascular Disease in Preterm Infants is Associated with Late Respiratory Outcomes in Childhood. Am J Respir Crit Care Med. 2018 Oct 10. [Epub ahead of print] PubMed PMID: 30303395
• Pammi M, Lal CV, Wagner BD, Mourani PM, Lohmann P, Luna RA, Sisson A, Shivanna B, Hollister EB, Abman SH, Versalovic J, Connett GJ, Bhandari V, Ambalavanan N. Airway Microbiome and Development of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review. J Pediatr. 2019 Jan;204:126-133.e2. PubMed PMID: 30297287
• Ehrmann DE, Mourani PM, Abman SH, Poindexter BB, Morrow LA, Wagner BD, Di Maria MV. Echocardiographic Measurements of Right Ventricular Mechanics in Infants with Bronchopulmonary Dysplasia at 36 Weeks Postmenstrual Age. J Pediatr. 2018 Dec;203:210-217.e1. PubMed PMID: 30244987
• Reeder RW, Girling A, Wolfe H, Holubkov R, Berg RA, Naim MY, Meert KL, Tilford B, Carcillo JA, Hamilton M, Bochkoris M, Hall M, Maa T, Yates AR, Sapru A, Kelly R, Federman M, Michael Dean J, McQuillen PS, Franzon D, Pollack MM, Siems A, Diddle J, Wessel DL, Mourani PM, Zebuhr C, Bishop R, Friess S, Burns C, Viteri S, Hehir DA, Whitney Coleman R, Jenkins TL, Notterman DA, Tamburro RF, Sutton RM. Improving outcomes after pediatric cardiac arrest - the ICU-Resuscitation Project: study protocol for a randomized controlled trial. Trials. 2018 Apr 3;19(1):213. PubMed PMID: 29615134
• Barhight MF, Lusk J, Brinton J, Stidham T, Soranno DE, Faubel S, Goebel J, Mourani PM, Gist KM. Hyperchloremia is independently associated with mortality in critically ill children who ultimately require continuous renal replacement therapy. Pediatr Nephrol. 2018 Jun;33(6):1079-1085. PubMed PMID: 29404689
• Alvarez RV, Palmer C, Czaja AS, Peyton C, Silver G, Traube C, Mourani PM, Kaufman J. Delirium is a Common and Early Finding in Patients in the Pediatric Cardiac Intensive Care Unit. J Pediatr. 2018 Apr;195:206-212. PubMed PMID: 29395177
• Maddux AB, DeWitt PE, Mourani PM, Bennett TD. Hospital Readmissions After Pediatric Trauma. Pediatr Crit Care Med. 2018 Jan;19(1):e31-e40. PubMed PMID: 29210926
• Abman SH, Mourani P, Wagner B. Reply to Ong and Schechter: Is It Acceptable to Assess Prenatal Smoking Risk to Infants without Considering Socioeconomic Status?. Am J Respir Crit Care Med. 2018 Apr 1;197(7):966-967. PubMed PMID: 29111777
• Wagner BD, Babinec AE, Carpenter C, Gonzalez S, O'Brien G, Rollock K, Williamson K, Mourani PM, Abman SH. Proteomic Profiles Associated with Early Echocardiogram Evidence of Pulmonary Vascular Disease in Preterm Infants. Am J Respir Crit Care Med. 2018 Feb 1;197(3):394-397. PubMed PMID: 28650220
• Ladd AK, Skillman HE, Haemer MA, Mourani PM. Preventing Underfeeding and Overfeeding: A Clinician's Guide to the Acquisition and Implementation of Indirect Calorimetry. Nutr Clin Pract. 2018 Apr;33(2):198-205. PubMed PMID: 28549221
• Siems A, Banks R, Holubkov R, Meert KL, Bauerfeld C, Beyda D, Berg RA, Bulut Y, Burd RS, Carcillo J, Dean JM, Gradidge E, Hall MW, McQuillen PS, Mourani PM, Newth CJL, Notterman DA, Priestley MA, Sapru A, Wessel DL, Yates AR, Zuppa AF, Pollack MM. Structured Chart Review: Assessment of a Structured Chart Review Methodology. Hosp Pediatr. 2020 Jan;10(1):61-69. PubMed PMID: 31879317
• Lindberg DM, Stence NV, Grubenhoff JA, Lewis T, Mirsky DM, Miller AL, O'Neill BR, Grice K, Mourani PM, Runyan DK. Feasibility and Accuracy of Fast MRI Versus CT for Traumatic Brain Injury in Young Children. Pediatrics. 2019 Oct;144(4). PubMed PMID: 31533974
• Hornik CP, Yogev R, Mourani PM, Watt KM, Sullivan JE, Atz AM, Speicher D, Al-Uzri A, Adu-Darko M, Payne EH, Gelber CE, Lin S, Harper B, Melloni C, Cohen-Wolkowiez M, Gonzalez D. Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents. J Clin Pharmacol. 2019 Dec;59(12):1606-1619. PubMed PMID: 31317556
• Roberts AL, Sammons JS, Mourani PM, Thomas NJ, Yehya N. Specific Viral Etiologies Are Associated With Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2019 Sep;20(9):e441-e446. PubMed PMID: 31246746
• Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019;10:1005. PubMed PMID: 31139182
• Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 Dec;588(7836):E5. PubMed PMID: 33208953
• Meert KL, Reeder RW, Maddux AB, Banks R, Berg RA, Newth CJ, Hall MW, Quasney M, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, McGalliard J, Dean JM, Zimmerman JJ. Health-Related Quality of Life After Community-Acquired Septic Shock in Children With Preexisting Severe Developmental Disabilities. Pediatr Crit Care Med. 2020 Nov 6. [Epub ahead of print] PubMed PMID: 33156209
• Quan J, Langelier C, Kuchta A, Batson J, Teyssier N, Lyden A, Caldera S, McGeever A, Dimitrov B, King R, Wilheim J, Murphy M, Ares LP, Travisano KA, Sit R, Amato R, Mumbengegwi DR, Smith JL, Bennett A, Gosling R, Mourani PM, Calfee CS, Neff NF, Chow ED, Kim PS, Greenhouse B, DeRisi JL, Crawford ED. FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences. Nucleic Acids Res. 2019 Aug 22;47(14):e83. PubMed PMID: 31114866
• Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 Nov;587(7834):466-471. PubMed PMID: 33116313
• Fink EL, Maddux AB, Pinto N, Sorenson S, Notterman D, Dean JM, Carcillo JA, Berg RA, Zuppa A, Pollack MM, Meert KL, Hall MW, Sapru A, McQuillen PS, Mourani PM, Wessel D, Amey D, Argent A, Brunow de Carvalho W, Butt W, Choong K, Curley MAQ, Del Pilar Arias Lopez M, Demirkol D, Grosskreuz R, Houtrow AJ, Knoester H, Lee JH, Long D, Manning JC, Morrow B, Sankar J, Slomine BS, Smith M, Olson LM, Watson RS. A Core Outcome Set for Pediatric Critical Care. Crit Care Med. 2020 Dec;48(12):1819-1828. PubMed PMID: 33048905
• Ziegler KM, Haywood JD, Sontag MK, Mourani PM. Application of the New Centers for Disease Control and Prevention Surveillance Criteria for Ventilator-Associated Events to a Cohort of PICU Patients Identifies Different Patients Compared With the Previous Definition and Physician Diagnosis. Crit Care Med. 2019 Jul;47(7):e547-e554. PubMed PMID: 30985451
• Faustino EVS, Hirshberg EL, Asaro LA, Biagas KV, Pinto N, Srinivasan V, Bagdure DN, Steil GM, Coughlin-Wells K, Wypij D, Nadkarni VM, Agus MSD, Mourani PM, Chima R, Thomas NJ, Li S, Pinto A, Newth C, Hassinger A, Bysani K, Rehder KJ, Kandil S, Wintergerst K, Schwarz A, Marsillio L, Cvijanovich N, Pham N, Quasney M, Flori H, Federman M, Nett S, Viteri S, Schneider J, Medar S, Sapru A, McQuillen P, Babbitt C, Lin JC, Jouvet P, Yanay O, Allen C. Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children. Crit Care Med. 2019 May;47(5):706-714. PubMed PMID: 30789401
• Zuppa AF, Zane NR, Moorthy G, Dalton HJ, Abraham A, Reeder RW, Carcillo JA, Yates AR, Meert KL, Berg RA, Sapru A, Mourani P, Notterman DA, Dean JM, Gastonguay MR. A Population Pharmacokinetic Analysis to Study the Effect of Extracorporeal Membrane Oxygenation on Cefepime Disposition in Children. Pediatr Crit Care Med. 2019 Jan;20(1):62-70. PubMed PMID: 30431557
• Mourani PM, Mandell EW, Meier M, Younoszai A, Brinton JT, Wagner BD, Arjaans S, Poindexter BB, Abman SH. Early Pulmonary Vascular Disease in Preterm Infants Is Associated with Late Respiratory Outcomes in Childhood. Am J Respir Crit Care Med. 2019 Apr 15;199(8):1020-1027. PubMed PMID: 30303395
• Pammi M, Lal CV, Wagner BD, Mourani PM, Lohmann P, Luna RA, Sisson A, Shivanna B, Hollister EB, Abman SH, Versalovic J, Connett GJ, Bhandari V, Ambalavanan N. Airway Microbiome and Development of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review. J Pediatr. 2019 Jan;204:126-133.e2. PubMed PMID: 30297287
• Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL. Therapeutic Alliance Between Bereaved Parents and Physicians in the PICU. Pediatr Crit Care Med. 2020 Oct 9. [Epub ahead of print] PubMed PMID: 33044415
• Maddux AB, Pinto N, Fink EL, Hartman ME, Nett S, Biagas K, Killien EY, Dervan LA, Christie LM, Luckett PM, Loftis L, Lackey M, Ringwood M, Smith M, Olson L, Sorenson S, Meert KL, Notterman DA, Pollack MM, Mourani PM, Watson RS. Postdischarge Outcome Domains in Pediatric Critical Care and the Instruments Used to Evaluate Them: A Scoping Review. Crit Care Med. 2020 Dec;48(12):e1313-e1321. PubMed PMID: 33009099
• Wagner BD, Sontag MK, Harris JK, Miller JI, Morrow L, Robertson CE, Stephens MJ, Poindexter BB, Abman SH, Mourani PM. Prenatal complications are associated with the postnatal airway host response and microbiota in intubated preterm infants. J Matern Fetal Neonatal Med. 2019 May;32(9):1499-1506. PubMed PMID: 29157044
• Mourani PM, Sontag MK, Williamson KM, Harris JK, Reeder R, Locandro C, Carpenter TC, Maddux AB, Ziegler K, Simões EAF, Osborne CM, Ambroggio L, Leroue MK, Robertson CE, Langelier C, DeRisi JL, Kamm J, Hall MW, Zuppa AF, Carcillo J, Meert K, Sapru A, Pollack MM, McQuillen P, Notterman DA, Dean JM, Wagner BD. Temporal airway microbiome changes related to ventilator associated pneumonia in children. Eur Respir J. 2020 Oct 2. [Epub ahead of print] PubMed PMID: 33008935
• Wong HR, Reeder RW, Banks R, Berg RA, Meert KL, Hall MW, McQuillen PS, Mourani PM, Chima RS, Sorenson S, Varni JW, McGalliard J, Zimmerman JJ. Biomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation. Pediatr Crit Care Med. 2020 Sep 29. [Epub ahead of print] PubMed PMID: 33003178
• Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Oct;21(10):869-878. PubMed PMID: 32667767
• Ward SL, Flori HR, Bennett TD, Sapru A, Mourani PM, Thomas NJ, Khemani RG. Design and Rationale for Common Data Elements for Clinical Research in Pediatric Critical Care Medicine. Pediatr Crit Care Med. 2020 Nov;21(11):e1038-e1041. PubMed PMID: 32639472
• Starr MC, Banks R, Reeder RW, Fitzgerald JC, Pollack MM, Meert KL, McQuillen PS, Mourani PM, Chima RS, Sorenson S, Varni JW, Hingorani S, Zimmerman JJ. Severe Acute Kidney Injury Is Associated With Increased Risk of Death and New Morbidity After Pediatric Septic Shock. Pediatr Crit Care Med. 2020 Sep;21(9):e686-e695. PubMed PMID: 32569242
• Murphy LK, Palermo TM, Meert KL, Reeder R, Dean JM, Banks R, Berg RA, Carcillo JA, Chima R, McGalliard J, Haaland W, Holubkov R, Mourani PM, Pollack MM, Sapru A, Sorenson S, Varni JW, Zimmerman J. Longitudinal Trajectories of Caregiver Distress and Family Functioning After Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2020 Sep;21(9):787-796. PubMed PMID: 32541376
• Berger JT, Maddux AB, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Yates AR, Notterman DA, Holubkov R, Dean JM, Wessel DL. Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure. Pediatr Crit Care Med. 2020 Aug;21(8):708-719. PubMed PMID: 32195895
• Barhight MF, Brinton JT, Soranno DE, Faubel S, Mourani PM, Gist KM. Effects of hyperchloremia on renal recovery in critically ill children with acute kidney injury. Pediatr Nephrol. 2020 Jul;35(7):1331-1339. PubMed PMID: 32152726
• Fink EL, Jarvis JM, Maddux AB, Pinto N, Galyean P, Olson LM, Zickmund S, Ringwood M, Sorenson S, Dean JM, Carcillo JA, Berg RA, Zuppa A, Pollack MM, Meert KL, Hall MW, Sapru A, McQuillen PS, Mourani PM, Watson RS. Development of a core outcome set for pediatric critical care outcomes research. Contemp Clin Trials. 2020 Apr;91:105968. PubMed PMID: 32147572
• Landis WP, Morgan RW, Reeder RW, Graham K, Siems A, Diddle JW, Pollack MM, Maa T, Fernandez RP, Yates AR, Tilford B, Ahmed T, Meert KL, Schneiter C, Bishop R, Mourani PM, Naim MY, Friess S, Burns C, Manga A, Franzon D, Tabbutt S, McQuillen PS, Horvat CM, Bochkoris M, Carcillo JA, Huard L, Federman M, Sapru A, Viteri S, Hehir DA, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Wolfe HA, Sutton RM. Variability in chest compression rate calculations during pediatric cardiopulmonary resuscitation. Resuscitation. 2020 Apr;149:127-133. PubMed PMID: 32088254
• Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW. Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar;48(3):329-337. PubMed PMID: 32058370
• Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW. Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Crit Care Med. 2020 Mar;48(3):319-328. PubMed PMID: 32058369
• Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG. RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. J Allergy Clin Immunol. 2020 Jun;145(6):1673-1680.e11. PubMed PMID: 32035159
• Arjaans S, Wagner BD, Mourani PM, Mandell EW, Poindexter BB, Berger RMF, Abman SH. Early angiogenic proteins associated with high risk for bronchopulmonary dysplasia and pulmonary hypertension in preterm infants. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L644-L654. PubMed PMID: 31967847
• James KA, Gralla J, Ridall LA, Do TN, Czaja AS, Mourani PM, Ciafaloni E, Cunniff C, Donnelly J, Oleszek J, Pandya S, Price E, Yang ML, Auerbach SR. Left ventricular dysfunction in Duchenne muscular dystrophy. Cardiol Young. 2020 Feb;30(2):171-176. PubMed PMID: 31964455
• Siems A, Banks R, Holubkov R, Meert KL, Bauerfeld C, Beyda D, Berg RA, Bulut Y, Burd RS, Carcillo J, Dean JM, Gradidge E, Hall MW, McQuillen PS, Mourani PM, Newth CJL, Notterman DA, Priestley MA, Sapru A, Wessel DL, Yates AR, Zuppa AF, Pollack MM. Structured Chart Review: Assessment of a Structured Chart Review Methodology. Hosp Pediatr. 2020 Jan;10(1):61-69. PubMed PMID: 31879317

Professional Memberships

• American Academy of Pediatrics (AAP), Member
• American Thoracic Society (ATS), Member
• Society of Critical Care Medicine, Member
• Pediatric Acute Lung Injury and Sepsis Investigator Network, Member
• Society for Pediatric Research, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• Children's Hospital Colorado

Specialty Information

Specialties

• Pediatrics, Board Certification (1997, 2002)
• Pediatric Critical Care Medicine, Board Certification (2002, 2009)
• Pediatric Pulmonology, Board Certification (2004, 2011)
• Certificate in Clinical Science Investigation, Certificate (2005)

Conditions & Treatments

• Lungs and Breathing - Chronic Lung Disease of Prematurity (Bronchopulmonary Dysplasia)
• Lungs and Breathing
• Lungs and Breathing - Pulmonary Hypertension
• Critical Care