University of Colorado President's Diversity Award Nominee, CU
(2019)
Woman of the Year, Alpha Chi Omega National Sorority
(2016)
Best Doctors in the US - Neonatal Neurology, Best Doctors
(2015)
2015-present
Fellow of the American Heart Association, American Heart Association/American Stroke Association
(2013)
Research Interests
My research focuses on neuroplacentology - how the maternal-placental-fetal system informs fetal programming and neurodevelopmental outcomes including perinatal brain injury and beyond. My special expertise is disorders of coagulation in pregnancy, the placenta, and fetus.
Publications
Armstrong J, Lakin A, Blumberg-Romero L, Campbell T, Heldens J, Lieu C, Neiman J, Sandene E, Steinbeiss M, Thompson D, Tregellas J, Flaig T, Higgins J. Clinical Research Reactivation During the COVID-19 Pandemic: An Academic Center Process and Lessons for the Future. J Trans Sci, 2022 8:1-8, DOI: 10.15761/JTS.1000468
Armstrong J, Lakin A, Blumberg-Romero L, Campbell T, Heldens J, Lieu C, Neiman J, Sandene E, Steinbeiss M, Thompson D, Tregellas J, Flaig T, Higgins J. Clinical research reactivation during the COVID-19 pandemic: An academic center process and lessons for the future. J Transl Sci. 2022 Feb;8(1). PubMed PMID: 37122588
Armstrong J, Lakin A, Blumberg-Romero L, Campbell T, Heldens J, Lieu C, Neiman J, Sandene E, Steinbeiss M, Thompson D, Tregellas J, Flaig T, Higgins J. Clinical Research Reactivation During the COVID-19 Pandemic: An Academic Center Process and Lessons for the Future. J Trans Sci, 2022 8:1-8, DOI: 10.15761/JTS.1000468
Smith N, Warren BB, Smith J, Jacobson L, Armstrong J, Kim J, Di Paola J, Manco-Johnson M. Antithrombin deficiency: A pediatric disorder. Thromb Res. 2021 Jun;202:45-51. PubMed PMID: 33725558
Giamberardino W, Winn VD, Armstrong J. Risk Factors for Clinically Significant Intraventricular Hemorrhage in Pregnancies Complicated by Preterm Premature Rupture of Membranes. J Preg Neo Med, 2021
Penn AA, Wintermark P, Chalak LF, Armstrong J, Redline R, Scher MS, Nelson KB on behalf of the Newborn Brain Society Guidelines and Publications Committee. Placental Contributions to Neonatal Encephalopathy. SFNM. 2021
CU-Anschutz/Denver COMIRB Guidance on Research in Pregnant Women
CU-Anschutz/Denver COMIRB Guidance on Placental/Fetal/Neonatal Research
What That Temporary Pause in J&J Vaccine Means for Neurology , Neurology Today, May 6, 2021
Sotiros A, Thornhill D, Post MD, Winn VD, Armstrong J. Inflammatory cytokines, placental pathology, and neurological outcomes in infants born to preterm preeclamptic mothers. PLoS One. 2021;16(11):e0260094. PubMed PMID: 34780565
Flume PA, Berbari EF, Viera L, Hess R, Higgins J, Armstrong J, Rice L, True L, Shaker R, Buse JB, Panettieri RA Jr. Managing the risks and benefits of clinical research in response to a pandemic. J Clin Transl Sci. 2021;5(1):e105. PubMed PMID: 35757679
Paulson L, Thornhill D, Armstrong J. Clinic Follow up and Neurological Disability in Children Following Pregnancies Complicated by Preterm Rupture of Membranes and Preeclampsia. J Child Dev Disord. 2021;7(5). PubMed PMID: 35782107
Sotiros A, Thornhill D, Post MD, Winn VD, Armstrong J. Inflammatory cytokines, placental pathology, and neurological outcomes in infants born to preterm preeclamptic mothers. PLoS One. 2021;16(11):e0260094. PubMed PMID: 34780565
Flume PA, Berbari EF, Viera L, Hess R, Higgins J, Armstrong J, Rice L, True L, Shaker R, Buse JB, Panettieri RA Jr. Managing the risks and benefits of clinical research in response to a pandemic. J Clin Transl Sci. 2021;5(1):e105. PubMed PMID: 35757679
Smith N, Warren BB, Smith J, Jacobson L, Armstrong J, Kim J, Di Paola J, Manco-Johnson M. Antithrombin deficiency: A pediatric disorder. Thromb Res. 2021 Jun;202:45-51. PubMed PMID: 33725558
Paulson L, Thornhill D, Armstrong J. Clinic Follow up and Neurological Disability in Children Following Pregnancies Complicated by Preterm Rupture of Membranes and Preeclampsia. J Child Dev Disord. 2021;7(5). PubMed PMID: 35782107
Giamberardino W, Winn VD, Armstrong J. Risk Factors for Clinically Significant Intraventricular Hemorrhage in Pregnancies Complicated by Preterm Premature Rupture of Membranes. J Preg Neo Med, 2021 5:4. PMCID PMC9224317
Penn AA, Wintermark P, Chalak LF, Armstrong J, Redline R, Scher MS, Nelson KB on behalf of the Newborn Brain Society Guidelines and Publications Committee. Placental Contributions to Neonatal Encephalopathy. Semin Fetal Neonatal Med. 2021 Aug;26(4):101276. PMID 34420894, DOI: 10.1016/j/siny.2021.101276
Felling RJ, Hassanein SMA, Armstrong J, Aversa L, Billinghurst L, Goldenberg NA, Lee JE, Maxwell EC, Noetzel MJ, Lo W. Treatment and outcome of childhood cerebral sinovenous thrombosis. Neurol Clin Pract. 2020 Jun;10(3):232-244. PubMed PMID: 32642325
Salehi Omran S, Parikh NS, Poisson S, Armstrong J, Merkler AE, Prabhu M, Navi BB, Riley LE, Fink ME, Kamel H. Association between Pregnancy and Cervical Artery Dissection. Ann Neurol. 2020 Jun 11. [Epub ahead of print] PubMed PMID: 32525238
Hoffman JE, Ryan M, Wittenberg B, Armstrong J, Greenan K, Wilkinson C. Successful treatment of hemorrhagic brainstem cavernous malformation with hematoma evacuation and postoperative propranolol. Childs Nerv Syst. 2020 Sep;36(9):2109-2112. PubMed PMID: 32303833
Fox CK, Jordan LC, Beslow LA, Armstrong J, Mackay MT, deVeber G. Children with post-stroke epilepsy have poorer outcomes one year after stroke. Int J Stroke. 2018 Oct;13(8):820-823. PubMed PMID: 29956597
Bernard TJ, Beslow LA, Manco-Johnson MJ, Armstrong-Wells J, Boada R, Weitzenkamp D, Hollatz A, Poisson S, Amlie-Lefond C, Lo W, deVeber G, Goldenberg NA, Dowling MM, Roach ES, Fullerton HJ, Benseler SM, Jordan LC, Kirton A, Ichord RN. Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies. Stroke. 2016 Oct;47(10):2443-9. PubMed PMID: 27633024
Fox CK, Mackay MT, Dowling MM, Pergami P, Titomanlio L, Deveber G. Prolonged or recurrent acute seizures after pediatric arterial ischemic stroke are associated with increasing epilepsy risk. Dev Med Child Neurol. 2016 Jul 16. [Epub ahead of print] PubMed PMID: 27422813
Bernard TJ, Beslow LA, Manco-Johnson MJ, Armstrong-Wells J, Boada R, Weitzenkamp D, Hollatz A, Poisson S, Amlie-Lefond C, Lo W, deVeber G, Goldenberg NA, Dowling MM, Roach ES, Fullerton HJ, Benseler SM, Jordan LC, Kirton A, Ichord RN. Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies. Stroke. 2016 Oct;47(10):2443-9. PubMed PMID: 27633024
Stence NV, Mirsky DM, Deoni SC, Armstrong-Wells J. Paradoxical centrally increased diffusivity in perinatal arterial ischemic stroke. Pediatr Radiol. 2015 Aug 4. [Epub ahead of print] PubMed PMID: 26238967
Joachim E, Goldenberg NA, Bernard TJ, Armstrong-Wells J, Stabler S, Manco-Johnson MJ. The methylenetetrahydrofolate reductase polymorphism (MTHFR c.677C>T) and elevated plasma homocysteine levels in a U.S. pediatric population with incident thromboembolism. Thromb Res. 2013 Aug;132(2):170-4. PubMed PMID: 23866722
Armstrong-Wells J, Post MD, Donnelly M, Manco-Johnson MJ, Fisher BM, Winn VD. Patterns of placental pathology in preterm premature rupture of membranes. J Dev Orig Health Dis. 2013 Jun;4(3):249-255. PubMed PMID: 23828732
Goldenberg NA, Bernard TJ, Hillhouse J, Armstrong-Wells J, Galinkin J, Knapp-Clevenger R, Jacobson L, Marcovina SM, Manco-Johnson MJ. Elevated lipoprotein (a), small apolipoprotein (a), and the risk of arterial ischemic stroke in North American children. Haematologica. 2013 May;98(5):802-7. PubMed PMID: 23349301
Bernard TJ, Armstrong-Wells J, Goldenberg NA. The institution-based prospective inception cohort study: design, implementation, and quality assurance in pediatric thrombosis and stroke research. Semin Thromb Hemost. 2013 Feb;39(1):10-4. PubMed PMID: 23269572
Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke. J Pediatr. 2013 May;162(5):1041-6.e1. PubMed PMID: 23260102
Kedia S, Stence N, Manco-Johnson M, Armstrong-Wells J, Bernard TJ. Late cytotoxic edema in 2 children with hemiplegia: hemiplegic migraine or stroke?. Headache. 2012 Apr;52(4):674-8. PubMed PMID: 22404149
Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-Dimer, and Risk of Poor Neurologic Outcome in Childhood-Onset Arterial Ischemic Stroke. J Pediatr. 2012 Dec 19. [Epub ahead of print] PubMed PMID: 23260102
Bernard TJ, Armstrong-Wells J, Goldenberg NA. The Institution-Based Prospective Inception Cohort Study: Design, Implementation, and Quality Assurance in Pediatric Thrombosis and Stroke Research. Semin Thromb Hemost. 2012 Dec 26. [Epub ahead of print] PubMed PMID: 23269572
Bernard TJ, Manco-Johnson MJ, Lo W, MacKay MT, Ganesan V, DeVeber G, Goldenberg NA, Armstrong-Wells J, Dowling MM, Roach ES, Tripputi M, Fullerton HJ, Furie KL, Benseler SM, Jordan LC, Kirton A, Ichord R. Towards a consensus-based classification of childhood arterial ischemic stroke. Stroke. 2012 Feb;43(2):371-7. PubMed PMID: 22156694
Saver JL, Warach S, Janis S, Odenkirchen J, Becker K, Benavente O, Broderick J, Dromerick AW, Duncan P, Elkind MS, Johnston K, Kidwell CS, Meschia JF, Schwamm L, National Institute of Neurological Disorders and Stroke (NINDS) Stroke Common Data Element Working Group. Standardizing the structure of stroke clinical and epidemiologic research data: the National Institute of Neurological Disorders and Stroke (NINDS) Stroke Common Data Element (CDE) project. Stroke. 2012 Apr;43(4):967-73. PubMed PMID: 22308239
Brain and Nervous System - Neurovascular Conditions
Brain and Nervous System - Stroke
Blood / Lymphatic System - Clotting Disorders
Blood / Lymphatic System
Brain and Nervous System
Clinical Interests
While in medical school, I discovered that working with brain-injured children was a rewarding privilege. Children’s disabilities not only affected themselves but the entire family unit. The more I worked with these children, the more I felt that if we were able to prevent brain injury before birth, the personal, familial, and societal benefits would be substantial. I have been able to combine my research interests in pregnancy with my passion for caring for disabled children and their families.
General Information
Medical Schools:
MD, University of California, San Francisco, School of Medicine
(2002)
Graduate Schools:
MPH, University of California, Berkeley
(2001)
Undergraduate Schools:
BA, University of California–San Diego (CA)
(1997)
Residency Programs:
University of California (San Francisco) Program, Chief Resident, Neurology (2008)
University of California (San Francisco) Program, Pediatrics (2004)