Kevin Deane, MD

Professor, Medicine-Rheumatology


FacultyPhoto
Medical School
  • MD, Loma Linda University School of Medicine (1997)
Graduate School
  • PhD, University of Colorado Denver (2011)
Undergraduate School
  • BA, University of California–Davis (CA) (1997)
Internship
  • University of Colorado (1998)
Fellowships
  • University of Colorado, Rheumatology (2004)
Languages
English
Department
Medicine-Rheumatology

Professional Titles

  • Professor of Medicine

Recognitions

  • Golden Apple Teaching Award, University of Colorado (2001)
    Also awarded in 1999
  • Top Doctor, Denver-area magazine 5280 (2023)

Research Interests

Much of my research is focused on learning how we can identify individuals who are at risk of getting autoimmune disease before they are sick, and then prevent that disease from developing. In particular, I am the lead investigator on a trial in the USA called ‘StopRA’ where we identify people at-risk for future RA through a blood test, and then investigate whether treating them with a drug can delay or prevent future disease. You can learn more about this study as well as my other research in rheumatoid arthritis and other autoimmune diseases by visiting www.stop-ra.org or calling (303) 724-8330.

Publications

  • Ferucci ED, Majka DS, Parrish LA, Moroldo MB, Ryan M, Passo M, Thompson SD, Deane KD, Rewers M, Arend WP, Glass DN, Norris JM, Holers VM. Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum. 2005 Jan;52(1):239-46
  • Deane KD, West SG. Antiphospholipid Antibodies as a Cause of Pulmonary Capillaritis and Diffuse Alveolar Hemorrhage: A Case Series and Literature Review. Sem Arthritis Rheum 2005;35:154-165
  • Deane KD. Adamantiades-Behcet’s Disease. In: Head and Neck Manifestations of Systemic Disease. Harris JP, Weisman M, editors. Publication pending June 2006
  • Deane KD, West SG. Effectiveness and Safety of Therapies in Rheumatoid Arthritis. Journal of Musculoskeletal Medicine. Publication pending March/April 2006
  • Deane KD, West SG. Differential diagnosis of the crystal-induced arthropathies: acute monarthritis. In: Crystal-Induced Arthropathies: Gout, Pseudogout, and Apatite Associated Syndromes. Wortmann RL et al, editors. Publication pending 2006
  • Deane KD, West SG. Differential diagnosis of the crystal-induced arthropathies: acute monarthritis. In: Crystal-Induced Arthropathies: Gout, Pseudogout, and Apatite-Associated Syndromes. Wortmann RL et al, editors. Taylor & Francis Group, New York, 2006. pp 135-156.
  • Deane KD, West SG. Increased effectiveness in the newer rheumatoid arthritis therapies. Journal of Musculoskeletal Medicine 2006;23(3):171-180
  • Deane KD. Managing co-morbidities in rheumatoid arthritis. J Musculoskeletal Medicine 2006;23(11):S24-S31
  • Deane KD. Preventing and managing osteoporosis in rheumatoid arthritis. J Musculoskeletal Medicine 2006;23(12):838-844
  • Bhatia SS, Majka DS, Kittelson JM, Parrish LA, Ferucci ED, Deane KD, Arend WP, Rewers M, Holers VM, Norris JM. Rheumatoid factor seropositivity is inversely associated with oral contraceptive use in women without rheumatoid arthritis. Ann Rheum Dis. 2006 Jul 25; [Epub ahead of print]
  • Young KA, Parrish LA, Zerbe GO, Rewers M, Deane KD, Michael Holers V, Norris JM. Perinatal and early childhood risk factors associated with rheumatoid factor positivity in a healthy paediatric population. Ann Rheum Dis. 2007 Feb;66(2):179-83
  • Majka DS, Deane KD, Parrish LA, Lazar AA, Barón AE, Walker CW, Rubertone MV, Gilliland WR, Norris JM, Holers VM. The duration of pre-clinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis. Ann Rheum Dis. 2007 Nov 1; [Epub ahead of print]
  • Deane KD, Hueber W, Lazar AA, Tomooka BH, Parrish LA, Parish MC, Baron AE, Norris JM, Robinson WH, Holers, VM. Autoantibodies Precede Cytokine/Chemokine and C-Reactive Protein Elevations in the Pre-Clinical Period of Rheumatoid Arthritis (RA) Development. Arthritis Rheum 2007;56(9)Suppl:S318 Abstract 748
  • Hueber W, Tomooka BH, Deane KD, Parrish LA, Holers VM, Robinson WH. Autoantibody profiling in pre-disease RA samples. Arthritis Rheum 2007;56(9):Suppl:S517 Abstract 1289
  • Deane KD. Adamantiades-Behcet’s Disease. In: Head and Neck Manifestations of Systemic Disease. Harris JP, Weisman M, editors. Informa Healthcare USA, Inc, 2007:27-40
  • Deane KD, West SG. Other traditional disease-modifying antirheumatic drugs: monotherapy and combination therapy. In: Rheumatoid arthritis. Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, editors. Mosby, Elsevier, Philadelphia, PA, USA, 2009:325-336.
  • Deane KD, El-Gabalawy H. Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE. Nat Rev Rheumatol. 2014 Feb 11. [Epub ahead of print] PubMed PMID: 24514912
  • Demoruelle MK, Norris JM, Holers VM, Harris JK, Deane KD. The lung microbiome differs in asymptomatic subjects at elevated risk of future rheumatoid arthritis compared with healthy control subjects. Ann Am Thorac Soc. 2014 Jan;11 Suppl 1:S74. PubMed PMID: 24437417
  • Kuller LH, Mackey RH, Walitt BT, Deane KD, Holers VM, Robinson WH, Sokolove J, Chang Y, Liu S, Parks CG, Wright NC, Moreland LW. Determinants of mortality among postmenopausal women who report rheumatoid arthritis in the Women's Health Initiative. Arthritis Rheum. 2013 Dec 23. [Epub ahead of print] PubMed PMID: 24375393
  • Deane KD. Can rheumatoid arthritis be prevented?. Best Pract Res Clin Rheumatol. 2013 Aug;27(4):467-85. PubMed PMID: 24315049
  • Demoruelle MK, Deane KD, Holers VM. When and where does inflammation begin in rheumatoid arthritis?. Curr Opin Rheumatol. 2014 Jan;26(1):64-71. PubMed PMID: 24247116
  • Moreau KL, Deane KD, Meditz AL, Kohrt WM. Tumor necrosis factor-a inhibition improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. Atherosclerosis. 2013 Oct;230(2):390-6. PubMed PMID: 24075772
  • Willis VC, Demoruelle MK, Derber LA, Chartier-Logan CJ, Parish MC, Pedraza IF, Weisman MH, Norris JM, Holers VM, Deane KD. Sputum autoantibodies in patients with established rheumatoid arthritis and subjects at risk of future clinically apparent disease. Arthritis Rheum. 2013 Oct;65(10):2545-54. PubMed PMID: 23817979
  • Young KA, Deane KD, Derber LA, Hughes-Austin JM, Wagner CA, Sokolove J, Weisman MH, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Robinson WH, Holers VM, Norris JM. Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis. Arthritis Rheum. 2013 Aug;65(8):1995-2004. PubMed PMID: 23754702
  • Demoruelle MK, Parish MC, Derber LA, Kolfenbach JR, Hughes-Austin JM, Weisman MH, Gilliland W, Edison JD, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Norris JM, Holers VM, Deane KD. Performance of anti-cyclic citrullinated Peptide assays differs in subjects at increased risk of rheumatoid arthritis and subjects with established disease. Arthritis Rheum. 2013 Sep;65(9):2243-52. PubMed PMID: 23686569
  • Gan RW, Deane KD, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Holers VM, Norris JM. Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA. Ann Rheum Dis. 2013 Dec;72(12):2002-5. PubMed PMID: 23572338
  • Walitt B, Mackey R, Kuller L, Deane KD, Robinson W, Holers VM, Chang YF, Moreland L. Predictive Value of Autoantibody Testing for Validating Self-reported Diagnoses of Rheumatoid Arthritis in the Women's Health Initiative. Am J Epidemiol. 2013 Mar 13. [Epub ahead of print] PubMed PMID: 23492764
  • Demoruelle MK, Deane KD. Reply: To PMID 22183986. Arthritis Rheum. 2013 Jun;65(6):1673-4. PubMed PMID: 23436248
  • Deane KD, Nicolls MR. Developing better biomarkers for connective tissue disease-associated interstitial lung disease: citrullinated hsp90 autoantibodies in rheumatoid arthritis. Arthritis Rheum. 2013 Apr;65(4):864-8. PubMed PMID: 23400799
  • Demoruelle MK, Kahr A, Verilhac K, Deane K, Fischer A, West S. Recent-onset systemic lupus erythematosus complicated by acute respiratory failure. Arthritis Care Res (Hoboken). 2013 Feb;65(2):314-23. PubMed PMID: 22972558
  • Hughes-Austin JM, Deane KD, Derber LA, Kolfenbach JR, Zerbe GO, Sokolove J, Lahey LJ, Weisman MH, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Robinson WH, Holers VM, Norris JM. Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA). Ann Rheum Dis. 2013 Jun;72(6):901-7. PubMed PMID: 22915618
  • Gan RW, Trouw LA, Shi J, Toes RE, Huizinga TW, Demoruelle MK, Kolfenbach JR, Zerbe GO, Deane KD, Edison JD, Gilliland WR, Norris JM, Holers VM. Anti-carbamylated Protein Antibodies Are Present Prior to Rheumatoid Arthritis and Are Associated with Its Future Diagnosis. J Rheumatol. 2015 Jan 15. [Epub ahead of print] PubMed PMID: 25593232
  • Catrina AI, Deane KD, Scher JU. Gene, environment, microbiome and mucosal immune tolerance in rheumatoid arthritis. Rheumatology (Oxford). 2014 Dec 23. [Epub ahead of print] PubMed PMID: 25539828
  • Bykerk VP, Costenbader KH, Deane K. Preclinical rheumatic disease. Rheum Dis Clin North Am. 2014 Nov;40(4):xv-xviii. PubMed PMID: 25437295
  • Finckh A, Deane KD. Prevention of rheumatic diseases: strategies, caveats, and future directions. Rheum Dis Clin North Am. 2014 Nov;40(4):771-85. PubMed PMID: 25437291
  • Liang MH, Couto MC, Duarte CC, Gall V, White P, Naides S, Schumacher HR Jr, Hwang AS, Holers VM, Deane KD, Gupta S, Ho IC, Finckh A, Kopec J, Choi CB, Sayre EC. An Internet-based technique for the identification of persons with symptoms of inflammatory polyarthritis of less than 12 weeks. Clin Rheumatol. 2014 Oct 24. [Epub ahead of print] PubMed PMID: 25339123
  • Sparks JA, Iversen MD, Miller Kroouze R, Mahmoud TG, Triedman NA, Kalia SS, Atkinson ML, Lu B, Deane KD, Costenbader KH, Green RC, Karlson EW. Personalized Risk Estimator for Rheumatoid Arthritis (PRE-RA) Family Study: rationale and design for a randomized controlled trial evaluating rheumatoid arthritis risk education to first-degree relatives. Contemp Clin Trials. 2014 Sep;39(1):145-57. PubMed PMID: 25151341
  • Deane KD. Preclinical rheumatoid arthritis (autoantibodies): an updated review. Curr Rheumatol Rep. 2014 May;16(5):419. PubMed PMID: 24643396
  • Kuller LH, Mackey RH, Walitt BT, Deane KD, Holers VM, Robinson WH, Sokolove J, Chang Y, Liu S, Parks CG, Wright NC, Moreland LW. Determinants of mortality among postmenopausal women in the women's health initiative who report rheumatoid arthritis. Arthritis Rheumatol. 2014 Mar;66(3):497-507. PubMed PMID: 24574208
  • Kuller LH, Mackey RH, Walitt BT, Deane KD, Holers VM, Robinson WH, Sokolove J, Chang Y, Moreland LW. Rheumatoid arthritis in the Women's Health Initiative: methods and baseline evaluation. Am J Epidemiol. 2014 Apr 1;179(7):917-26. PubMed PMID: 24569640
  • Deane KD, El-Gabalawy H. Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE. Nat Rev Rheumatol. 2014 Apr;10(4):212-28. PubMed PMID: 24514912
  • Demoruelle MK, Deane KD, Holers VM. When and where does inflammation begin in rheumatoid arthritis?. Curr Opin Rheumatol. 2014 Jan;26(1):64-71. PubMed PMID: 24247116
  • Deane KD. Bursitis, Tendinitis, Myofascial Pain, and Fibromyalgia. In: Conn’s Current Therapy 2009. Rakel RE and Bope ET, editors. Saunders, Elsevier, Philadelphia, PA, USA, 2009:994-998.
  • Gizinski AM, Mascolo M, Loucks JL, Kervitsky A, Meehan RT, Brown KK, Holers VM, Deane KD. Rheumatoid arthritis(RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent RA. Clin Rheumatology, 2009; in press.
  • Feser M, Derber LA, Deane KD, Lezotte DC, Weisman MH, Buckner JH, Mikuls T, O’Dell J, Gregersen PK, Holers VM, Norris JM. Plasma 25,OH vitamin D levels are not associated with rheumatoid arthritis-related autoantibodies in individuals at elevated risk for rheumatoid arthritis. J Rheumatology 2009, in press.
  • Bursitis, Tendinitis, Myofascial Pain, and Fibromyalgia. In: Conn's Current Therapy, 2009. Editors: Rakel RE, Bope, ET. Saunders/Elsevier, Philadelphia PA, 2009.
  • Deane KD. Do We Need Early ACPA Testing in Inflammatory Arthritis?. J Rheumatol. 2016 Jan;43(1):1-2. PubMed PMID: 26523028
  • Deane KD. Rheumatoid arthritis: Autoantibodies, citrullinated histones and initiation of synovitis. Nat Rev Rheumatol. 2015 Dec;11(12):688-9. PubMed PMID: 26416595
  • Gan RW, Young KA, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Clare-Salzler MJ, Deane KD, Holers VM, Norris JM. Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study. Rheumatology (Oxford). 2015 Sep 13. [Epub ahead of print] PubMed PMID: 26370400
  • Mackey RH, Kuller LH, Deane KD, Walitt BT, Chang YF, Holers VM, Robinson WH, Tracy RP, Hlatky MA, Eaton CB, Liu S, Freiberg MS, Talabi MB, Schelbert EB, Moreland LW. Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative. Arthritis Rheumatol. 2015 Sep;67(9):2311-22. PubMed PMID: 25988241
  • Gan RW, Trouw LA, Shi J, Toes RE, Huizinga TW, Demoruelle MK, Kolfenbach JR, Zerbe GO, Deane KD, Edison JD, Gilliland WR, Norris JM, Holers VM. Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis. J Rheumatol. 2015 Apr;42(4):572-9. PubMed PMID: 25593232
  • Liang MH, Couto MC, Duarte CC, Gall V, White P, Naides S, Schumacher HR Jr, Hwang AS, Holers VM, Deane KD, Gupta S, Ho IC, Finckh A, Kopec J, Choi CB, Sayre EC. An Internet-based technique for the identification of persons with symptoms of inflammatory polyarthritis of less than 12 weeks. Clin Rheumatol. 2015 Mar;34(3):465-70. PubMed PMID: 25339123
  • Deane KD, Striebich CC, Goldstein BL, Derber LA, Parish MC, Feser ML, Hamburger EM, Brake S, Belz C, Goddard J, Norris JM, Karlson EW, Holers VM. Identification of Undiagnosed Inflammatory Arthritis in a Community Health-Fair Screen. Arthritis Rheum. 2009 Dec 15;61(12):1642-9
  • Kolfenbach JR, Deane KD, Derber LA, O’Donnell C, Weisman MH, Buckner JH, Gersuk VH, Wei S, Mikuls TR, O’Dell JR, Gregersen PK, Keating RM, Norris JM, Holers VM. A prospective approach to investigatingthe natural history of pre-clinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA. Arthritis Rheum. 2009 Dec 15;61(12):1735-42.
  • Gizinski AM, Mascolo M, Loucks JL, Kervitsky A, Meehan RT, Brown KK, Holers VM, Deane KD. Rheumatoid arthritis(RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent RA. Clin Rheumatology, 2009;28(5):611-13.
  • Feser M, Derber LA, Deane KD, Lezotte DC, Weisman MH, Buckner JH, Mikuls T, O’Dell J, Gregersen PK, Holers VM, Norris JM. Plasma 25,OH vitamin D levels are not associated with rheumatoid arthritis-related autoantibodies in individuals at elevated risk for rheumatoid arthritis. J Rheumatol. 2009 May;36(5):943-6. Epub 2009 Mar 13.
  • Kelmenson LB, Demoruelle MK, Deane KD. The Complex Role of the Lung in the Pathogenesis and Clinical Outcomes of Rheumatoid Arthritis. Curr Rheumatol Rep. 2016 Nov;18(11):69. PubMed PMID: 27796844
  • FitzGerald J, Mandl LA, Cron RQ, Lacaille D, Deane K, Franchin G, Lim SS, Park CC. Rheumatology fellows’ perception n training and careers in academia: The American College of Rheumatology Fellow Research and Academic Training Survey. Arthritis Rheum 2009;61(2):266-273.
  • Deane KD. Vaccines in adult patients with rheumatic disease: balancing risks and benefits. WebMD:Medscape Internal Medicine. On-line publication 6/18/2009
  • Deane KD, West SG. RA therapies in 2009: the latest on drug effectiveness. J Musculoskeletal Medicine, October 2009(Suppl):S8-S16.
  • Deane KD, Norris JM, Holers VM. Pre-Clinical Rheumatoid Arthritis: Identification, Evaluation and Future Directions for Investigation. Rheumatic Disease Clinics of North America, in press.
  • Kolfenbach JR, Deane KD, Derber LA, O’Donnell C, Weisman MH, Buckner JH, Mikuls TR, O’Dell, JR, Gregersen PK, Keating RM, Norris JM, Holers VM. Association of rheumatoid arthritis (RA)-related autoimmunity and joint findings in unaffected at-risk populations (Abstract 371). Arthritis Rheum 2009;60(10)Suppl:S137
  • Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 2016 Oct 20;1(17):e90045. PubMed PMID: 27777982
  • Altan Ercan, Jing Cui, Dereck E.W. Chatterton, Kevin D. Deane, Melissa M. Hazen, William Brintnell, Colin I. O’Donnell, Lezlie A. Derber, Michael E. Weinblatt, Nancy A. Shadick, David A. Bell, Ewa Cairns, Daniel H. Solomon, V. Michael Holers, Pauline M. Rudd, and David M. Lee. IgG galactosylation aberrancy precedes disease onset, correlates with disease activity and is prevalent in autoantibodies in rheumatoid arthritis. Arthritis Rheum. 2010; Apr 29 [Epub ahead of print].
  • Kolfenbach, JR, Deane, KD, Derber, LA, O’Donnell, CI, Rosen, A, Darrah, E, Norris, JM, Holers, VM. Autoimmunity to Peptidyl Arginine Deiminase Type 4 Precedes Clinical Onset of Rheumatoid Arthritis. Arthritis Rheum 2010; May 23 [Epub ahead of print].
  • Kinslow JD, Blum LK, Deane KD, Demoruelle MK, Okamoto Y, Parish MC, Kongpachith S, Lahey LJ, Norris JM, Robinson WH, Holers VM. Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis. Arthritis Rheumatol. 2016 Oct;68(10):2372-83. PubMed PMID: 27273876
  • Sparks JA, Chang SC, Deane KD, Gan RW, Kristen Demoruelle M, Feser ML, Moss L, Buckner JH, Keating RM, Costenbader KH, Gregersen PK, Weisman MH, Mikuls TR, O'Dell JR, Michael Holers V, Norris JM, Karlson EW. Associations of Smoking and Age With Inflammatory Joint Signs Among Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients: Results From Studies of the Etiology of Rheumatoid Arthritis. Arthritis Rheumatol. 2016 Aug;68(8):1828-38. PubMed PMID: 26866831
  • Mikuls TR, Payne JB, Deane KD, Thiele GM. Autoimmunity of the lung and oral mucosa in a multisystem inflammatory disease: The spark that lights the fire in rheumatoid arthritis?. J Allergy Clin Immunol. 2016 Jan;137(1):28-34. PubMed PMID: 26768760
  • Deane KD. Do We Need Early ACPA Testing in Inflammatory Arthritis?. J Rheumatol. 2016 Jan;43(1):1-2. PubMed PMID: 26523028
  • Gan RW, Young KA, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Clare-Salzler MJ, Deane KD, Holers VM, Norris JM. Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study. Rheumatology (Oxford). 2016 Feb;55(2):367-76. PubMed PMID: 26370400
  • Catrina AI, Deane KD, Scher JU. Gene, environment, microbiome and mucosal immune tolerance in rheumatoid arthritis. Rheumatology (Oxford). 2016 Mar;55(3):391-402. PubMed PMID: 25539828
  • Kolfenbach JR, Deane KD. 11 Rheumatology findings not to miss. Medscape, publish date 29-Aug-2016. http://www.medscape.com/features/slideshow/rheumatologic-findings?src=WNL_infoc_160903_MSCPEDIT&uac=156096DJ&impID=1190603&faf=1
  • Kolfenbach JR, Deane KD. Diagnosing and treating rheumatic skin disorders. Medscape, publish date 18-Dec-2015. http://www.medscape.com/features/slideshow/rheumatic-skin-disorders?src=WNL_infoc_160903_MSCPEDIT&uac=156096DJ&impID=1190603&faf=1
  • Deane KD, O’Donnell CI, Hueber W, Majka DS, Lazar AA, Derber LA, Gilliland WR, Edison JD, Norris JM, Robinson WH, Holers VM. The number of elevated cytokines/chemokines in pre-clinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner. Arthritis Rheum 2010; Jul 1 [Epub ahead of print].
  • Deane KD, Tyler KN, Johnson DW, Tanabe JL, Oskarrson BE, Nitka EE, Brass E, Davies JK, Striebich CC. Susac's Syndrome and Pregnancy: A Case Report and Discussion of Disease Management. J Clin Rheum, 2011. In press.
  • Antibodies to citrullinated protein antigens (ACPAs): clinical and pathophysiologic significance. Demoruelle MK, Deane KD. Current Rheumatology Reports, 2011. In press.
  • Demoruelle MK, Bowers E, Lahey LJ, Sokolove J, Purmalek M, Seto NL, Weisman MH, Norris JM, Kaplan MJ, Holers VM, William RH, Deane KD. Antibody Responses to Citrullinated and Non-Citrullinated Antigens in the Sputum of Subjects with and At-Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2017 Dec 20. [Epub ahead of print] PubMed PMID: 29266801
  • Nonrestorative Sleep in Fibromyalgia: From Assessment to Therapy -- Focus on Treatment Options. Deane K, Doghramji P. Medscape, December 30, 2010: http://www.medscape.org/viewarticle/734692.
  • Hughes-Austin JM, Gan RW, Deane KD, Weisman MH, Demoruelle MK, Sokolove J, Robinson WH, Holers VM, Norris JM, Ix JH. Association of Antibodies to Citrullinated Protein Antigens with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis. Am J Nephrol. 2017;46(6):481-487. PubMed PMID: 29237149
  • Nonrestorative Sleep in Fibromyalgia: From Assessment to Therapy -- Focus on Features of Fibromyalgia-Associated Nonrestorative Sleep. Deane K, Doghramji K. Medscape, December 30, 2010: http://www.medscape.org/viewarticle/734747
  • Deane KD, Demoruelle MK, Kelmenson LB, Kuhn KA, Norris JM, Holers VM. Genetic and environmental risk factors for rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2017 Feb;31(1):3-18. PubMed PMID: 29221595
  • Demoruelle MK, Weisman MH, Simonian PL, Lynch DA, Sachs PB, Pedraza IF, Harrington AR, Kolfenbach JR, Striebich CC, Pham QN, Strickland CD, Petersen BD, Parish MC, Derber LA, Norris JM, Holers VM, Deane KD. Airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity? In press, Arthritis Rheum 2011.
  • Fischer A, Solomon JJ, du Bois RM, Deane KD, Olson AL, Fernandez-Perez ER, Huie TJ, Stevens AD, Gill MB, Rabinovitch AM, Lynch DA, Burns DA, Pineiro IS, Groshong SD, Achcar RDD, Brown KK, Martin RJ, Swigris JJ. Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease. In press. Respiratory Medicine, 2012.
  • Deane KD. Learning about the natural history of rheumatoid arthritis development through prospective study of subjects at high risk of rheumatoid arthritis-related autoimmunity. In press. Arthritis Rheum, 2012.
  • Gan RW, Bemis EA, Demoruelle MK, Striebich CC, Brake S, Feser ML, Moss L, Clare-Salzler M, Holers VM, Deane KD, Norris JM. The association between omega-3 fatty acid biomarkers and inflammatory arthritis in an anti-citrullinated protein antibody positive population. Rheumatology (Oxford). 2017 Dec 1;56(12):2229-2236. PubMed PMID: 29029330
  • Sparks JA, Iversen MD, Yu Z, Triedman NA, Prado MG, Miller Kroouze R, Kalia SS, Atkinson ML, Mody EA, Helfgott SM, Todd DJ, Dellaripa PF, Bermas BL, Costenbader KH, Deane KD, Lu B, Green RC, Karlson EW. Disclosure of personalized rheumatoid arthritis risk using genetics, biomarkers, and lifestyle factors to motivate health behavior improvements:A randomized controlled trial. Arthritis Care Res (Hoboken). 2017 Oct 12. [Epub ahead of print] PubMed PMID: 29024454
  • Birru Talabi M, Mackey RH, Kuller LH, Dorman JS, Deane KD, Robinson WH, Walitt BT, Chang Y, Holers VM, Liu S, Moreland LW. Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study. Am J Epidemiol. 2017 Jul 15;186(2):245-254. PubMed PMID: 28459968
  • Moreau KL, Meditz A, Deane KD, Kohrt WM. Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. Am J Physiol Heart Circ Physiol. 2012 Mar;302(5):H1211-8. Epub 2012 Jan 13. PMCID: Pending.
  • Ercan A, Kohrt WM, Cui J, Deane KD, Pezer M, Yu EW, Hausmann JS, Campbell H, Kaiser UB, Rudd PM, Lauc G, Wilson JF, Finkelstein JS, Nigrovic PA. Estrogens regulate glycosylation of IgG in women and men. JCI Insight. 2017 Feb 23;2(4):e89703. PubMed PMID: 28239652
  • Deane KD, Striebich CC, Holers VM. Editorial: Prevention of Rheumatoid Arthritis: Now Is the Time, but How to Proceed?. Arthritis Rheumatol. 2017 May;69(5):873-877. PubMed PMID: 28217918
  • Demoruelle MK, Harrall KK, Ho L, Purmalek MM, Seto NL, Rothfuss HM, Weisman MH, Solomon JJ, Fischer A, Okamoto Y, Kelmenson LB, Parish MC, Feser M, Fleischer C, Anderson C, Mahler M, Norris JM, Kaplan MJ, Cherrington BD, Holers VM, Deane KD. Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients. Arthritis Rheumatol. 2017 Jun;69(6):1165-1175. PubMed PMID: 28182854
  • Gan RW, Demoruelle MK, Deane KD, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Fingerlin TE, Zerbe GO, Clare-Salzler MJ, Holers VM, Norris JM. Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis. Ann Rheum Dis. 2017 Jan;76(1):147-152. PubMed PMID: 27190099
  • Karlson EW, Deane KD. Environmental and gene-environment interactions and risk of rheumatoid arthritis. In press. Rheum Dis Clin North Am, 2012.
  • Sokolove J, Bromberg R, Tibshirani RJ, Deane KD, Lahey LJ, Derber LA, Chandra PE, Edison JD, Gilliland WR, Tibshirani RJ, Norris JM, Holers VM, and Robinson WH. Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis. In press. PLoS ONE, 2012.
  • Ford JA, Liu X, Marshall AA, Zaccardelli A, Prado MG, Wiyarand C, Lu B, Karlson EW, Schur PH, Deane KD, Sparks JA. Impact of Cyclic Citrullinated Peptide Antibody Level on Progression to Rheumatoid Arthritis in Clinically Tested CCP-Positive Patients Without RA. Arthritis Care Res (Hoboken). 2018 Dec 20. [Epub ahead of print] PubMed PMID: 30570827
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  • Okamato Y, Ghosh T, Okamoto T, Schuyler RP, Seifert J, Charry LL, Visser A, Feser M, Fleischer C, Pedrick C, August J, Moss L, Bemis EA, Norris JM, Kuhn KA, Demoruelle MK, Deane KD, Ghosh D, Holers VM, Hsieh EWY. Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14(hi) monocytes. J Autoimmun. 2021 Feb;117:102581. PubMed PMID: 33310262
  • Bemis EA, Demoruelle MK, Seifert JA, Polinski KJ, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, ODell JR, Keating RM, Deane KD, Holers VM, Norris JM. Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting. Ann Rheum Dis. 2021 Feb;80(2):154-161. PubMed PMID: 32928740
  • Juge PA, Lee JS, Lau J, Kawano-Dourado L, Rojas Serrano J, Sebastiani M, Koduri G, Matteson E, Bonfiglioli K, Sawamura M, Kairalla R, Cavagna L, Bozzalla Cassione E, Manfredi A, Mejia M, Rodríguez-Henriquez P, González-Pérez MI, Falfán-Valencia R, Buendia-Roldán I, Pérez-Rubio G, Ebstein E, Gazal S, Borie R, Ottaviani S, Kannengiesser C, Wallaert B, Uzunhan Y, Nunes H, Valeyre D, Saidenberg-Kermanac'h N, Boissier MC, Wemeau-Stervinou L, Flipo RM, Marchand-Adam S, Richette P, Allanore Y, Dromer C, Truchetet ME, Richez C, Schaeverbeke T, Lioté H, Thabut G, Deane KD, Solomon JJ, Doyle T, Ryu JH, Rosas I, Holers VM, Boileau C, Debray MP, Porcher R, Schwartz DA, Vassallo R, Crestani B, Dieudé P. Methotrexate and rheumatoid arthritis associated interstitial lung disease. Eur Respir J. 2021 Feb;57(2). PubMed PMID: 32646919
  • Deane KD, Holers VM. Rheumatoid Arthritis Pathogenesis, Prediction, and Prevention: An Emerging Paradigm Shift. Arthritis Rheumatol. 2021 Feb;73(2):181-193. PubMed PMID: 32602263
  • Moon JS, Younis S, Ramadoss NS, Iyer R, Sheth K, Sharpe O, Rao NL, Becart S, Carman JA, James EA, Buckner JH, Deane KD, Holers VM, Goodman SM, Donlin LT, Davis MM, Robinson WH. Cytotoxic CD8( ) T cells target citrullinated antigens in rheumatoid arthritis. Nat Commun. 2023 Jan 19;14(1):319. PubMed PMID: 36658110
  • Moore RE, Wang T, Duvvuri B, Feser ML, Deane KD, Solomon JJ, Nelson JL, Demoruelle MK, Lood C. Anti-mitochondrial antibodies predict erosive disease development in rheumatoid arthritis. Arthritis Rheumatol. 2022 Dec 29. [Epub ahead of print] PubMed PMID: 36580020
  • Deane KD. Targeting Environmental Risks to Prevent Rheumatic Disease. Rheum Dis Clin North Am. 2022 Nov;48(4):931-943. PubMed PMID: 36333004
  • Holers VM, Kuhn KA, Demoruelle MK, Norris JM, Firestein GS, James EA, Robinson WH, Buckner JH, Deane KD. Mechanism-driven strategies for prevention of rheumatoid arthritis. Rheumatol Autoimmun. 2022 Sep;2(3):109-119. PubMed PMID: 36312783
  • Chriswell ME, Lefferts AR, Clay MR, Hsu AR, Seifert J, Feser ML, Rims C, Bloom MS, Bemis EA, Liu S, Maerz MD, Frank DN, Demoruelle MK, Deane KD, James EA, Buckner JH, Robinson WH, Holers VM, Kuhn KA. Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Sci Transl Med. 2022 Oct 26;14(668):eabn5166. PubMed PMID: 36288282
  • Khassawneh B, Zhu C, Barkes B, Vestal B, Shrock S, Gillespie M, Pacheco K, Deane KD, Maier LA, Li QZ, Hamzeh N. Autoantibody profile in sarcoidosis, analysis from the GRADS sarcoidosis cohort. PLoS One. 2022;17(10):e0274381. PubMed PMID: 36264970
  • Seifert JA, Bemis EA, Ramsden K, Lowell C, Polinski K, Feser M, Fleischer C, Demoruelle MK, Buckner J, Gregersen PK, Keating RM, Mikuls TR, O'Dell JR, Weisman MH, Deane KD, Norris JM, Steere AC, Holers VM. Association of antibodies to Prevotella copri in anti-CCP-positive individuals at-risk for developing rheumatoid arthritis and in those with early or established rheumatoid arthritis. Arthritis Rheumatol. 2022 Oct 19. [Epub ahead of print] PubMed PMID: 36259174
  • Fleischer CL, Bemis EA, Feser ML, Kormendi VA, Zhang A, Ketcham K, White SD, Striebich CC, Deane KD, Harrison M. Preferences and Insights for Participation in a Rheumatoid Arthritis Clinical Prevention Trial: A Mixed-Methods Study. ACR Open Rheumatol. 2022 Nov;4(11):974-982. PubMed PMID: 36112074
  • Finckh A, Gilbert B, Hodkinson B, Bae SC, Thomas R, Deane KD, Alpizar-Rodriguez D, Lauper K. Global epidemiology of rheumatoid arthritis. Nat Rev Rheumatol. 2022 Oct;18(10):591-602. PubMed PMID: 36068354
  • Bergstedt DT, Tarter WJ, Peterson RA, Feser ML, Parish MC, Striebich CC, Demoruelle MK, Moss L, Bemis EA, Norris JM, Holers VM, Edison JD, Thiele GM, Mikuls TR, Deane KD. Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis. Front Immunol. 2022;13:916277. PubMed PMID: 35812446
  • Vanderlinden LA, Bemis EA, Seifert J, Guthridge JM, Young KA, Demoruelle MK, Feser M, DeJager W, Macwana S, Mikuls TR, O'Dell JR, Weisman MH, Buckner J, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Deane KD, James JA, Holers VM, Norris JM. Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus. Front Immunol. 2022;13:881332. PubMed PMID: 35720397
  • Tsaltskan V, Nguyen K, Eaglin C, Holers VM, Deane KD, Firestein GS. Comparison of Web-Based Advertising and a Social Media Platform as Recruitment Tools for Underserved and Hard-to-Reach Populations in Rheumatology Clinical Research. ACR Open Rheumatol. 2022 Jul;4(7):623-630. PubMed PMID: 35536990
  • Purdue M, Zhang L, Vermeulen R, Smith MT, Hu W, Rhee J, Wen C, Huang Y, Tang X, Berndt SI, Frazer-Abel AA, Deane KD, Rothman N, Lan Q. Occupational trichloroethylene exposure and antinuclear antibodies: a cross-sectional study in China. Occup Environ Med. 2022 Oct;79(10):717-720. PubMed PMID: 35504721
  • Banda NK, Deane KD, Bemis EA, Strickland C, Seifert J, Jordan K, Goldman K, Morgan BP, Moreland LW, Lewis MJ, Pitzalis C, Holers VM. Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features. J Immunol. 2022 Jun 1;208(11):2482-2496. PubMed PMID: 35500934
  • Haville S, Deane KD. Pre-RA: Can early diagnosis lead to prevention?. Best Pract Res Clin Rheumatol. 2022 Mar;36(1):101737. PubMed PMID: 34991984
  • Matson SM, Deane KD, Peljto AL, Bang TJ, Sachs PB, Walts AD, Collora C, Ye S, Demoruelle MK, Humphries SM, Schwartz DA, Lee JS. Prospective Identification of Subclinical Interstitial Lung Disease in a Rheumatoid Arthritis Cohort Is Associated with the MUC5B Promoter Variant. Am J Respir Crit Care Med. 2022 Feb 15;205(4):473-476. PubMed PMID: 34874815
  • Fechtner S, Berens H, Bemis E, Johnson RL, Guthridge CJ, Carlson NE, Demoruelle MK, Harley JB, Edison JD, Norris JA, Robinson WH, Deane KD, James JA, Holers VM. Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles. Arthritis Rheumatol. 2022 Apr;74(4):597-603. PubMed PMID: 34605217
  • Okamoto Y, Devoe S, Seto N, Minarchick V, Wilson T, Rothfuss HM, Mohning MP, Arbet J, Kroehl M, Visser A, August J, Thomas SM, Charry LL, Fleischer C, Feser ML, Frazer-Abel AA, Norris JM, Cherrington BD, Janssen WJ, Kaplan MJ, Deane KD, Holers VM, Demoruelle MK. Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2022 Jan;74(1):38-48. PubMed PMID: 34369110
  • Parks CG, Wilson LE, Capello M, Deane KD, Hanash SM. Tumor-Associated and Systemic Autoimmunity in Pre-Clinical Breast Cancer among Post-Menopausal Women. Biomolecules. 2023 Oct 24;13(11). PubMed PMID: 38002248
  • James EA, Holers VM, Iyer R, Prideaux EB, Rao NL, Rims C, Muir VS, Posso SE, Bloom MS, Zia A, Elliott SE, Adamska JZ, Ai R, Brewer RC, Seifert JA, Moss L, Barzideh S, Demoruelle MK, Striebich CC, Okamoto Y, Sainbayar E, Crook AA, Peterson RA, Vanderlinden LA, Wang W, Boyle DL, Robinson WH, Buckner JH, Firestein GS, Deane KD. Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis. Nat Commun. 2023 Nov 22;14(1):7637. PubMed PMID: 37993439
  • Frost E, Hofmann JN, Huang WY, Parks CG, Frazer-Abel AA, Deane KD, Berndt SI. Antinuclear Antibodies Are Associated with an Increased Risk of Diffuse Large B-Cell Lymphoma. Cancers (Basel). 2023 Oct 31;15(21). PubMed PMID: 37958403
  • Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM 2nd, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF, Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature. 2023 Nov;623(7987):616-624. PubMed PMID: 37938773
  • Inamo J, Keegan J, Griffith A, Ghosh T, Horisberger A, Howard K, Pulford J, Murzin E, Hancock B, Jonsson AH, Seifert J, Feser ML, Norris JM, Cao Y, Apruzzese W, Louis Bridges S, Bykerk V, Goodman S, Donlin L, Firestein GS, Perlman H, Bathon JM, Hughes LB, Tabechian D, Filer A, Pitzalis C, Anolik JH, Moreland L, Guthridge JM, James JA, Brenner MB, Raychaudhuri S, Sparks JA, Michael Holers V, Deane KD, Lederer JA, Rao DA, Zhang F. Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. bioRxiv. 2023 Jul 4. PubMed PMID: 37461737
  • Lee JA, Mikuls TR, Deane KD, Sayles HR, Thiele GM, Edison JD, Wagner BD, Feser ML, Moss LK, Kelmenson LB, Robinson WH, Payne JB. Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study. Semin Arthritis Rheum. 2023 Apr;59:152176. PubMed PMID: 36812865
  • Brewer RC, Lanz TV, Hale CR, Sepich-Poore GD, Martino C, Swafford AD, Carroll TS, Kongpachith S, Blum LK, Elliott SE, Blachere NE, Parveen S, Fak J, Yao V, Troyanskaya O, Frank MO, Bloom MS, Jahanbani S, Gomez AM, Iyer R, Ramadoss NS, Sharpe O, Chandrasekaran S, Kelmenson LB, Wang Q, Wong H, Torres HL, Wiesen M, Graves DT, Deane KD, Holers VM, Knight R, Darnell RB, Robinson WH, Orange DE. Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Sci Transl Med. 2023 Feb 22;15(684):eabq8476. PubMed PMID: 36812347
  • Moon JS, Younis S, Ramadoss NS, Iyer R, Sheth K, Sharpe O, Rao NL, Becart S, Carman JA, James EA, Buckner JH, Deane KD, Holers VM, Goodman SM, Donlin LT, Davis MM, Robinson WH. Cytotoxic CD8( ) T cells target citrullinated antigens in rheumatoid arthritis. Nat Commun. 2023 Jan 19;14(1):319. PubMed PMID: 36658110
  • Moore RE, Wang T, Duvvuri B, Feser ML, Deane KD, Solomon JJ, Nelson JL, Demoruelle MK, Lood C. Prediction of Erosive Disease Development by Antimitochondrial Antibodies in Rheumatoid Arthritis. Arthritis Rheumatol. 2023 Jun;75(6):890-899. PubMed PMID: 36580020
  • Deane KD. Targeting Environmental Risks to Prevent Rheumatic Disease. Rheum Dis Clin North Am. 2022 Nov;48(4):931-943. PubMed PMID: 36333004
  • Holers VM, Kuhn KA, Demoruelle MK, Norris JM, Firestein GS, James EA, Robinson WH, Buckner JH, Deane KD. Mechanism-driven strategies for prevention of rheumatoid arthritis. Rheumatol Autoimmun. 2022 Sep;2(3):109-119. PubMed PMID: 36312783
  • Chriswell ME, Lefferts AR, Clay MR, Hsu AR, Seifert J, Feser ML, Rims C, Bloom MS, Bemis EA, Liu S, Maerz MD, Frank DN, Demoruelle MK, Deane KD, James EA, Buckner JH, Robinson WH, Holers VM, Kuhn KA. Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Sci Transl Med. 2022 Oct 26;14(668):eabn5166. PubMed PMID: 36288282
  • Khassawneh B, Zhu C, Barkes B, Vestal B, Shrock S, Gillespie M, Pacheco K, Deane KD, Maier LA, Li QZ, Hamzeh N. Autoantibody profile in sarcoidosis, analysis from the GRADS sarcoidosis cohort. PLoS One. 2022;17(10):e0274381. PubMed PMID: 36264970
  • Seifert JA, Bemis EA, Ramsden K, Lowell C, Polinski K, Feser M, Fleischer C, Demoruelle MK, Buckner J, Gregersen PK, Keating RM, Mikuls TR, O'Dell JR, Weisman MH, Deane KD, Norris JM, Steere AC, Holers VM. Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis. Arthritis Rheumatol. 2023 Apr;75(4):507-516. PubMed PMID: 36259174
  • Fleischer CL, Bemis EA, Feser ML, Kormendi VA, Zhang A, Ketcham K, White SD, Striebich CC, Deane KD, Harrison M. Preferences and Insights for Participation in a Rheumatoid Arthritis Clinical Prevention Trial: A Mixed-Methods Study. ACR Open Rheumatol. 2022 Nov;4(11):974-982. PubMed PMID: 36112074
  • Finckh A, Gilbert B, Hodkinson B, Bae SC, Thomas R, Deane KD, Alpizar-Rodriguez D, Lauper K. Global epidemiology of rheumatoid arthritis. Nat Rev Rheumatol. 2022 Oct;18(10):591-602. PubMed PMID: 36068354
  • Bergstedt DT, Tarter WJ, Peterson RA, Feser ML, Parish MC, Striebich CC, Demoruelle MK, Moss L, Bemis EA, Norris JM, Holers VM, Edison JD, Thiele GM, Mikuls TR, Deane KD. Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis. Front Immunol. 2022;13:916277. PubMed PMID: 35812446
  • Vanderlinden LA, Bemis EA, Seifert J, Guthridge JM, Young KA, Demoruelle MK, Feser M, DeJager W, Macwana S, Mikuls TR, O'Dell JR, Weisman MH, Buckner J, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Deane KD, James JA, Holers VM, Norris JM. Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus. Front Immunol. 2022;13:881332. PubMed PMID: 35720397
  • Tsaltskan V, Nguyen K, Eaglin C, Holers VM, Deane KD, Firestein GS. Comparison of Web-Based Advertising and a Social Media Platform as Recruitment Tools for Underserved and Hard-to-Reach Populations in Rheumatology Clinical Research. ACR Open Rheumatol. 2022 Jul;4(7):623-630. PubMed PMID: 35536990
  • Purdue M, Zhang L, Vermeulen R, Smith MT, Hu W, Rhee J, Wen C, Huang Y, Tang X, Berndt SI, Frazer-Abel AA, Deane KD, Rothman N, Lan Q. Occupational trichloroethylene exposure and antinuclear antibodies: a cross-sectional study in China. Occup Environ Med. 2022 Oct;79(10):717-720. PubMed PMID: 35504721
  • Banda NK, Deane KD, Bemis EA, Strickland C, Seifert J, Jordan K, Goldman K, Morgan BP, Moreland LW, Lewis MJ, Pitzalis C, Holers VM. Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features. J Immunol. 2022 Jun 1;208(11):2482-2496. PubMed PMID: 35500934
  • Haville S, Deane KD. Pre-RA: Can early diagnosis lead to prevention?. Best Pract Res Clin Rheumatol. 2022 Mar;36(1):101737. PubMed PMID: 34991984
  • Matson SM, Deane KD, Peljto AL, Bang TJ, Sachs PB, Walts AD, Collora C, Ye S, Demoruelle MK, Humphries SM, Schwartz DA, Lee JS. Prospective Identification of Subclinical Interstitial Lung Disease in a Rheumatoid Arthritis Cohort Is Associated with the MUC5B Promoter Variant. Am J Respir Crit Care Med. 2022 Feb 15;205(4):473-476. PubMed PMID: 34874815
  • Fechtner S, Berens H, Bemis E, Johnson RL, Guthridge CJ, Carlson NE, Demoruelle MK, Harley JB, Edison JD, Norris JA, Robinson WH, Deane KD, James JA, Holers VM. Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles. Arthritis Rheumatol. 2022 Apr;74(4):597-603. PubMed PMID: 34605217
  • Okamoto Y, Devoe S, Seto N, Minarchick V, Wilson T, Rothfuss HM, Mohning MP, Arbet J, Kroehl M, Visser A, August J, Thomas SM, Charry LL, Fleischer C, Feser ML, Frazer-Abel AA, Norris JM, Cherrington BD, Janssen WJ, Kaplan MJ, Deane KD, Holers VM, Demoruelle MK. Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2022 Jan;74(1):38-48. PubMed PMID: 34369110

Professional Memberships

  • American College of Rheumatology, Member

Practice Locations

UCHealth Rheumatology Clinic - Anschutz Medical Campus
1635 Aurora Ct
4th Floor
Aurora, CO 80045
720-848-7700

Hospital Affiliation
  • University of Colorado Hospital
  • Veterans Affairs Medical Center

Specialty Information

Specialties
  • Rheumatology, Board Certification (2004)
  • Internal Medicine, Board Certification (2001)
Clinical Interests
I am interested in the management of a wide-variety of autoimmune diseases including rheumatoid arthritis and lupus.

Public Speaking
Yes
I enjoy giving lectures to the general community as well as health-care providers and researchers on how autoimmune diseases like rheumatoid arthritis develop, and how we may ultimately be able to prevent these diseases.