Christopher Striebich, MD, PhD

Associate Professor, Medicine-Rheumatology

FacultyPhoto
Medical School
  • MD, University of Texas Medical Branch School of Medicine (1991)
Residency
  • University of Colorado, Internal Medicine (1994)
Fellowships
  • University of Colorado, Rheumatology (1997)
Languages
English
Department
Medicine-Rheumatology

Publications

  • Identification of Transcript Biomarkers in Active Lupus Using Stabilized Whole Blood
  • Systemic Lupus Erythematosus, in Rheumatology Secrets, 3rd ed., Sterling West ed., Elsevier, Philadelphia.
  • Drug Induced Lupus, in Rheumatology Secrets, 3rd ed., Sterling West ed., Elsevier, Philadelphia.
  • Variability in the biological response to anti-CD20 B-cell depletion in SLE Daniel Albert, MD, Jonathan Dunham, MD, Sadia Khan, MD, Janet Stansberry, RN, Sharon Kolasinski, MD, Donald Tsai, MD, PhD, Sally Pullman-Mooar, MD, Felicia Barnack, BA, Christopher Striebich, MD, PhD, R John Looney, MD, Eline T. Luning Prak, MD, PhD, Robert Kimberly, MD, Yawei Zhang, PhD, Robert Eisenberg, MD Ann Rheum Dis published online 4 Feb 2008;
  • Deane KD, Striebich CC, Goldstein BL, Derber LA, Parish MC, Feser M, Hamburger EM, Brake S, Belz C, Goddard J, Norris JM, Karlson EW, Holers VM. Identification of Undiagnosed Inflammatory Arthritis and Rheumatoid Arthritis in a 3 Community Health-Fair Screen. Arth Rheum, Submitted.
  • Deane, K., C.C. Striebich, B. Goldstein, L. Derber, M. Parish, M. Feser, E. Hamburger, S. Brake, C. Belz, J. Goddard, J. Norris, E.W. Karlson, V.M. Holers. Identification of Undiagnosed Inflammatory Arthritis in a Community Health-Fair Screen. Arthritis Res Ther. 2009;61:1642-1649.
  • Nonrenal disease activity following mycophenolate mofetil or intravenous cyclophosphamide as induction treatment for lupus nephritis: Findings in a multicenter, prospective, randomized, open-label, parallel-group clinical trial. Ginzler EM, Wofsy D, Isenberg D, Gordon C, Lisk L, Dooley MA; ALMS Group. Arthritis Rheum. 2010 Jan;62(1):211-21. Erratum in: Arthritis Rheum. 2010 Oct;62(10):3005. PMID:20039429
  • Susac Syndrome and Pregnancy: Disease Management. Deane KD, Tyler KN, Johnson DW, Tanabe JL, Oskarrson BE, Nitka EE, Brass E, Davies JK, Striebich CC. J Clin Rheumatol. 2011 Feb 10. PMID:21325959
  • Airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: Early injury or initiating site of autoimmunity? Demoruelle MK, Weisman MH, Simonian PL, Lynch DA, Sachs PB, Pedraza IF, Harrington AR, Kolfenbach JR, Striebich CC, Pham QN, Strickland CD, Petersen BD, Parish MC, Derber LA, Norris JM, Holers VM, Deane KD. Arthritis Rheum. 2011 Dec 19. [Epub ahead of print] PMID:22183986
  • Mycophenolate versus Azathioprine as Maintenance Therapy for Lupus Nephritis. Dooley MA, Jayne D, Ginzler EM, Isenberg D, Olsen NJ, Wofsy D, Eitner F, Appel GB, Contreras G, Laura Lisk L, Solomons N for the ALMS Group. N Engl J Med. 2011 Nov 17;365(20):1886-95. PMID:22087680
  • Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity? Demoruelle MK, Weisman MH, Simonian PL, Lynch DA, Sachs PB, Pedraza IF, Harrington AR, Kolfenbach JR, Striebich CC, Pham QN, Strickland CD, Petersen BD, Parish MC, Derber LA, Norris JM, Holers VM, Deane KD. Arthritis Rheum. 2012 Jun;64(6):1756-61. doi: 10.1002/art.34344. Epub 2011 Dec 19. PMID:22183986
  • Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes. Liubchenko GA, Appleberry HC, Striebich CC, Franklin KE, Derber LA, Holers VM, Lyubchenko T. J Autoimmun. 2013 Feb;40:111-21. PMID:23058039
  • Pedler M, Striebich CC, Eisenmesser EZ, Moldawer LM, Fujita M, Norris DA, Edwards CM. Identification of soluble Immunophilin FKBP52 as a potent macrophage activation factor. J Invest Dermatol. 2012. 132, S106.
  • Liubchenko GA, Appleberry HC, Striebich CC, Franklin KE, Derber LA, Holers VM, Lyubchenko T. Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes. J Autoimmun. 2013 Feb;40:111-21. PubMed PMID: 23058039
  • Health Fair Evaluations To Identify Subjects At-Risk For Future Inflammatory Arthritis and Rheumatoid Arthritis. Beck, Kristen E. MA MS2; Demoruelle, M. Kristen MD; Striebich, Christopher C. MD, PhD; Aiona, Kaylynn MPH; Feser, Marie L. MSPH; Derber, Lezlie A. MSPH; Brake, Stacey RN BSN; Lysengen, Jill ; Rosseisen, Laura ; Rhiannon, Julia J. MD; Weisman, Stuart M. MD; Norris, Jill M. MPH, PhD; Holers, V. Michael MD; Deane, Kevin D. MD, PhD
  • Prediction Of TNF Inhibitor Response In Rheumatoid Arthritis Patients Using Single Cell Network Profiling Of Intracellular Immune Signaling. Ptacek, Jason PhD; Hawtin, Rachael PhD; Louie, Brent PhD; Evensen, Erik PhD; Cordeiro, James ; Mittleman, Barbara MD; Atallah, Michelle BS; Cesano, Alessandra MD, PhD; Bingham, Clifton O. MD; Cofield, Stacey PhD; Curtis, Jeffrey R. MD, MPH, MS; Danila, Maria I. MD, MSc; Furie, Richard A. MD; Genovese, Mark C. MD; Levesque, Marc C. MD, PhD; Moreland, Larry W. MD; Nigrovic, Peter A. MD; O'Dell, James R. MD; Robinson, William H. MD, PhD; Shadick, Nancy A. MD, MPH; St Clair, E. William M.D.; Striebich, Christopher C. MD, PhD; Thiele, Geoffrey M Ph.D.; Gregersen, Peter K. MD; Bridges, S. Louis MD, PhD
  • Assessment Of The Diagnostic Accuracy Of Different Strategies For Health Fair Case-Finding For Undiagnosed Inflammatory Arthritis. Aiona, Kaylynn MPH; Striebich, Christopher C. MD, PhD; Demoruelle, M. Kristen MD; Rhiannon, Julia J. MD; Weisman, Stuart M. MD; Feser, Marie L. MSPH; Derber, Lezlie A. MSPH; Goddard, James H. BS MHA; Brake, Stacey RN BSN; Lysengen, Jill ; Rosseisen, Laura ; Hokanson, John E. MPH PhD; Baron, Anna E. PhD; Norris, Jill M. MPH, PhD; Holers, V. Michael MD; Deane, Kevin D. MD, PhD
  • Vashisht P, Dorschner JM, Jensen MA, Chrabot BS, Wampler-Muskardin T, Kern M, TETRAD Investigators, ABCoN consortium, Bridges Jr. SL, Gregersen PK, Niewold TB. Baseline serum interferon beta/alpha ratio predicts response to tumor necrosis factor alpha inhibition in rheumatoid arthritis. Presented at the American College of Rheumatology Annual Meeting; 2014 Nov 14-19; Boston, MA.
  • West SW. Rheumatology Secrets. 3rd ed. Mosby; 2014. Chapter 17, Drug-induced lupus; p. 137-140.
  • Novel Biomarkers From Peripheral Blood Mononuclear Cells Indicate Disease Activity In Rheumatoid Arthritis Patients. Ptacek, Jason PhD; Hawtin, Rachael PhD; Louie, Brent PhD; Evensen, Erik PhD; Cordeiro, James ; Mittleman, Barbara MD; Atallah, Michelle BS; Cesano, Alessandra MD, PhD; Bingham, Clifton O. MD; Cofield, Stacey PhD; Curtis, Jeffrey R. MD, MPH, MS; Danila, Maria I. MD, MSc; Furie, Richard A. MD; Genovese, Mark C. MD; Levesque, Marc C. MD, PhD; Moreland, Larry W. MD; Nigrovic, Peter A. MD; O'Dell, James R. MD; Robinson, William H. MD, PhD; Shadick, Nancy A. MD, MPH; St Clair, E. William M.D.; Striebich, Christopher C. MD, PhD; Thiele, Geoffrey M Ph.D.; Gregersen, Peter K. MD; Bridges, S. Louis MD, PhD
  • A Double-Blind Randomized Placebo-Controlled Trial Of Lovastatin in Patients with Rheumatoid Arthritis. Aranow, Cynthia MD, Cush, John J. MD; Bolster, Marcy B. MD; Striebich, Christopher C. MD, PhD; Dall'Era, Maria MD; Mackay, Meggan MD, MS; Olech, Ewa MD; Frech, Tracy M. MD; Box, J. MD; Keating, Richard M. MD; Wasko, Mary Chester M. MD, MSc; St Clair, E. William M.D.; Kivitz, Alan MD; Diamond, Betty MD; Davidson, Anne MBBS; Spychala, Meagan DrPH; Goldmuntz, Ellen A. MD, PhD
  • Prediction of TNF Inhibitor Response in Rheumatoid Arthritis Patients Using Single Cell Network Profiling of Intracellular Immune Signaling. J. Ptacek, R. Hawtin, B. Louie, E. Evensen, J. Cordeiro, B. Mittleman, M. Atallah, A. Cesano, C. O. Bingham III, S. S. Cofield, J. R. Curtis3, M. I. Danila3, R. Furie4, M. C. Genovese, M. C. Levesque, L. W. Moreland, P. A. Nigrovic, J. R. O'Dell, W. H. Robinson, N. A. Shadick, E. W. St Clair, C. C. Striebich, G. M. Thiele, P. K. Gregersen, S. L. Bridges, Jr.
  • Ptacek J, Hawtin RE, Evensen E, Cordeiro J, Atallah M, Marimpietri C, Cesano A, TETRAD Investigators, Gregersen PK, Bridges Jr., SL. Comparison of functional immune signaling profiles in peripheral blood mononuclear cells (PBMC) from rheumatoid arthritis (RA) patients versus healthy donors (HD) using Single Cell Network Profiling (SCNP).
  • Wampler Muskardin T, Vashisht P, Dorschner JM, Jensen MA, Chrabot BS, Kern M, Curtis JR, Danila MI, Cofield SS, Shadick N, Nigrovic PA, St Clair EW, Bingham CO 3rd, Furie R, Robinson W, Genovese M, Striebich CC, O'Dell JR, Thiele GM, Moreland LW, Levesque M, Bridges SL Jr, Gregersen PK, Niewold TB. Increased pretreatment serum IFN-ß/a ratio predicts non-response to tumour necrosis factor a inhibition in rheumatoid arthritis. Ann Rheum Dis. 2015 Nov 6. [Epub ahead of print] PubMed PMID: 26546586
  • Wampler Muskardin T, Vashisht P, Dorschner JM, Jensen MA, Chrabot BS, Kern M, Curtis JR, Danila MI, Cofield SS, Shadick N, Nigrovic PA, St Clair EW, Bingham CO 3rd, Furie R, Robinson W, Genovese M, Striebich CC, O'Dell JR, Thiele GM, Moreland LW, Levesque M, Bridges SL Jr, Gregersen PK, Niewold TB. Increased pretreatment serum IFN-ß/a ratio predicts non-response to tumour necrosis factor a inhibition in rheumatoid arthritis. Ann Rheum Dis. 2016 Oct;75(10):1757-62. PubMed PMID: 26546586
  • Ormseth MJ, Yancey PG, Solus JF, Louis Bridges S Jr, Curtis JR, Linton MF, Fazio S, Davies SS, Roberts LJ 2nd, Vickers KC, Kon V, Michael Stein C. Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis. Arthritis Rheumatol. 2016 Sep;68(9):2099-105. PubMed PMID: 26991245
  • Gan RW, Bemis EA, Demoruelle MK, Striebich CC, Brake S, Feser ML, Moss L, Clare-Salzler M, Holers VM, Deane KD, Norris JM. The association between omega-3 fatty acid biomarkers and inflammatory arthritis in an anti-citrullinated protein antibody positive population. Rheumatology (Oxford). 2017 Dec 1;56(12):2229-2236. PubMed PMID: 29029330
  • Deane KD, Striebich CC, Holers VM. Editorial: Prevention of Rheumatoid Arthritis: Now Is the Time, but How to Proceed?. Arthritis Rheumatol. 2017 May;69(5):873-877. PubMed PMID: 28217918
  • West SG, Pearson DW, Striebich CC, Goecker R, Kolfenbach JR. The Effect of Pre-appointment Consult Triage on Patient Selection and Revenue Generation in a University Rheumatology Practice. Arthritis Care Res (Hoboken). 2018 Jul 12. [Epub ahead of print] PubMed PMID: 29999252
  • West S, Pearson D, Striebich CC, Goecker R, Kolfenbach J. Effect of Pre-Appointment Consult Triage on Patient Selection and Revenue Generation in a University Rheumatology Practice. American College of Rheumatology Annual Meeting; 2017 Nov 4-8; San Diego, CA. Abstract no. 185.
  • Clowse ME, Wallace DJ, Furie RA, Petri MA, Pike MC, Leszczynski P, Neuwelt CM, Hobbs K, Keiserman M, Duca L, Kalunian KC, Galateanu C, Bongardt S, Stach C, Beaudot C, Kilgallen B, Gordon C. Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled Trials. Arthritis Rheumatol. 2017 Feb;69(2):362-375. PubMed PMID: 27598855
  • Bemis EA, Ellinwood N, Aiona K, Striebich CC, Deane KD. A Combination of Self-Reported Symptoms and ACPA Testing Can Identify Individuals with Previously Undiagnosed Inflammatory Arthritis in a Health-Fair Setting. American College of Rheumatology Annual Meeting; 2017 Nov 4-8; San Diego, CA. Abstract no. 1055.
  • Aranow C, Cush J, Bolster MB, Striebich CC, Dall'era M, Mackay M, Olech E, Frech T, Box J, Keating R, Wasko MC, St Clair W, Kivitz A, Huang W, Ricketts P, Welch B, Callahan S, Spychala M, Boyle K, York K, Keyes-Elstein L, Goldmuntz E, Diamond B, Davidson A. A double-blind, placebo-controlled, phase II, randomized study of lovastatin therapy in the treatment of mildly active rheumatoid arthritis. Rheumatology (Oxford). 2019 Oct 18. [Epub ahead of print] PubMed PMID: 31628482
  • Striebich CC. Drug-Induced Lupus Erythematosus. In: West SG, Kolfenbach J, editors. Rheumatology Secrets 4th ed. Philadelphia: Elsevier; 2019. p. 152-155.
  • Striebich CC. Osteonecrosis. In: West SG, Kolfenbach J, editors. Rheumatology Secrets 4th ed. Philadelphia: Elsevier; 2019. p. 435-440.
  • Polinski KJ, Bemis EA, Feser M, Seifert J, Demoruelle MK, Striebich CC, Brake S, O'Dell JR, Mikuls TR, Weisman MH, Gregersen PK, Keating RM, Buckner J, Nicassio P, Holers VM, Deane KD, Norris JM. Perceived stress and inflammatory arthritis: a prospective investigation in the Studies of the Etiologies of Rheumatoid Arthritis (SERA) cohort. Arthritis Care Res (Hoboken). 2019 Oct 10. [Epub ahead of print] PubMed PMID: 31600025
  • West SG, Pearson DW, Striebich CC, Goecker R, Kolfenbach JR. The Effect of Pre-Appointment Consultation Triage on Patient Selection and Revenue Generation in a University Rheumatology Practice. Arthritis Care Res (Hoboken). 2019 May;71(5):689-693. PubMed PMID: 29999252
  • Aranow C, Cush J, Bolster MB, Striebich CC, Dall'era M, Mackay M, Olech E, Frech T, Box J, Keating R, Wasko MC, St Clair W, Kivitz A, Huang W, Ricketts P, Welch B, Callahan S, Spychala M, Boyle K, York K, Keyes-Elstein L, Goldmuntz E, Diamond B, Davidson A. A double-blind, placebo-controlled, phase II, randomized study of lovastatin therapy in the treatment of mildly active rheumatoid arthritis. Rheumatology (Oxford). 2020 Jul 1;59(7):1505-1513. PubMed PMID: 31628482
  • Polinski KJ, Bemis EA, Feser M, Seifert J, Demoruelle MK, Striebich CC, Brake S, O'Dell JR, Mikuls TR, Weisman MH, Gregersen PK, Keating RM, Buckner J, Nicassio P, Holers VM, Deane KD, Norris JM. Perceived Stress and Inflammatory Arthritis: A Prospective Investigation in the Studies of the Etiologies of Rheumatoid Arthritis Cohort. Arthritis Care Res (Hoboken). 2020 Dec;72(12):1766-1771. PubMed PMID: 31600025
  • Ptacek J, Hawtin RE, Sun D, Louie B, Evensen E, Mittleman BB, Cesano A, Cavet G, Bingham CO 3rd, Cofield SS, Curtis JR, Danila MI, Raman C, Furie RA, Genovese MC, Robinson WH, Levesque MC, Moreland LW, Nigrovic PA, Shadick NA, O'Dell JR, Thiele GM, Clair EWS, Striebich CC, Hale MB, Khalili H, Batliwalla F, Aranow C, Mackay M, Diamond B, Nolan GP, Gregersen PK, Bridges SL Jr. Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. PLoS One. 2021 Jan 14;16(1):e0244187. doi: 10.1371/journal.pone.0244187. PMID: 33444321.
  • Ptacek J, Hawtin RE, Sun D, Louie B, Evensen E, Mittleman BB, Cesano A, Cavet G, Bingham CO 3rd, Cofield SS, Curtis JR, Danila MI, Raman C, Furie RA, Genovese MC, Robinson WH, Levesque MC, Moreland LW, Nigrovic PA, Shadick NA, O'Dell JR, Thiele GM, Clair EWS, Striebich CC, Hale MB, Khalili H, Batliwalla F, Aranow C, Mackay M, Diamond B, Nolan GP, Gregersen PK, Bridges SL Jr. Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. PLoS One. 2021;16(1):e0244187. PubMed PMID: 33444321
  • Jayne DRW, Merkel PA, Schall TJ, Bekker P. Avacopan for the Treatment of ANCA-Associated Vasculitis. N Engl J Med. 2021 Feb 18;384(7):599-609. PubMed PMID: 33596356
  • Fleischer CL, Bemis EA, Feser ML, Kormendi VA, Zhang A, Ketcham K, White SD, Striebich CC, Deane KD, Harrison M. Preferences and Insights for Participation in a Rheumatoid Arthritis Clinical Prevention Trial: A Mixed-Methods Study. ACR Open Rheumatol. 2022 Nov;4(11):974-982. PubMed PMID: 36112074
  • Bergstedt DT, Tarter WJ, Peterson RA, Feser ML, Parish MC, Striebich CC, Demoruelle MK, Moss L, Bemis EA, Norris JM, Holers VM, Edison JD, Thiele GM, Mikuls TR, Deane KD. Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis. Front Immunol. 2022;13:916277. PubMed PMID: 35812446
  • Cortazar FB, Niles JL, Jayne DRW, Merkel PA, Bruchfeld A, Yue H, Schall TJ, Bekker P; ADVOCATE Study Group. Renal Recovery for Patients with ANCA-Associated Vasculitis and Low eGFR in the ADVOCATE Trial of Avacopan. Kidney Int Rep. 2023 Feb 3;8(4):860-870. doi: 10.1016/j.ekir.2023.01.039. PMID: 37069984; PMCID: PMC10105055.
  • Conran C, Kolfenbach J, Kuhn K, Striebich C, Moreland L. A Review of Difficult-to-Treat Rheumatoid Arthritis: Definition, Clinical Presentation, and Management. Curr Rheumatol Rep. 2023 Dec;25(12):285-294. doi: 10.1007/s11926-023-01117-6. PMID: 37776482.
  • James EA, Holers VM, Iyer R, Prideaux EB, Rao NL, Rims C, Muir VS, Posso SE, Bloom MS, Zia A, Elliott SE, Adamska JZ, Ai R, Brewer RC, Seifert JA, Moss L, Barzideh S, Demoruelle MK, Striebich CC, Okamoto Y, Sainbayar E, Crook AA, Peterson RA, Vanderlinden LA, Wang W, Boyle DL, Robinson WH, Buckner JH, Firestein GS, Deane KD. Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis. Nat Commun. 2023 Nov 22;14(1):7637. doi: 10.1038/s41467-023-43091-8. PMID: 37993439; PMCID: PMC10665556.
  • Geetha D, Dua A, Yue H, Springer J, Salvarani C, Jayne D, Merkel P; ADVOCATE Study Group. Efficacy and safety of avacopan in patients with ANCA-associated vasculitis receiving rituximab in a randomised trial. Ann Rheum Dis. 2024 Jan 11;83(2):223-232. doi: 10.1136/ard-2023-224816. PMID: 37979959.
  • Holers VM, Frank RM, Clauw A, Seifert J, Zuscik M, Asokan S, Striebich C, Clay MR, Moreland LW, Banda NK. Potential causal role of synovial complement system activation in the development of post-traumatic osteoarthritis after anterior cruciate ligament injury or meniscus tear. Front Immunol. 2023 May 3;14:1146563. doi: 10.3389/fimmu.2023.1146563. PMID: 37207197; PMCID: PMC10189880.
  • Strand V, Jayne DRW, Horomanski A, Yue H, Bekker P, Merkel PA. The impact of treatment with avacopan on health-related quality of life in antineutrophil cytoplasmic antibody-associated vasculitis: a post-hoc analysis of data from the ADVOCATE trial. Lancet Rheumatol. 2023 Aug;5(8):e451-e460. PubMed PMID: 38251577

Practice Locations

UCHealth Rheumatology Clinic - Anschutz Medical Campus
1635 Aurora Ct
4th Floor
Aurora, CO 80045
720-848-7700

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Rheumatology, Board Certification (2001)
  • Internal Medicine, Board Certification
Clinical Interests
I am interested in treating Rheumatoid Arthritis, Systemic Lupus Erythematosus and in Clinical Trials in Rheumatic Diseases.


School of Medicine

CU Anschutz
Fitzsimons Building

13001 East 17th Place

Aurora, CO 80045

303.724.5375

School
General
Students