James Maloney, MD
Professor, Medicine-Pulmonary Sciences & Critical Care

Professional Titles

• Medical Director, UCH Pulmonary Ward
• Elected Member, UCH Medical Board

Research Interests

Teaching

Publications

• Zagona-Prizio C, Pascoe MA, Corbisiero MF, Simon VC, Mann SE, Mayer KA, Maloney JP. Cadaveric emergency cricothyrotomy training for non-surgeons using a bronchoscopy-enhanced curriculum. PLoS One. 2023;18(3):e0282403. PubMed PMID: 36952528
• Vargas Barahona L, Molina KC, Pedraza-Arévalo LC, Sillau S, Tagawa A, Scherger S, Chastain DB, Shapiro L, Tuells J, Franco-Paredes C, Hawkins KL, Maloney JP, Thompson GR 3rd, Henao-Martínez AF. Previous corticosteroid exposure associates with an increased Pneumocystis jirovecii pneumonia mortality among HIV-negative patients: a global research network with a follow-up multicenter case-control study. Ther Adv Infect Dis. 2023 Jan-Dec;10:20499361231159481. PubMed PMID: 36938147
• Arguinchona LM, Zagona-Prizio C, Joyce ME, Chan ED, Maloney JP. Microvascular significance of TGF-ß axis activation in COVID-19. Front Cardiovasc Med. 2022;9:1054690. PubMed PMID: 36684608
• Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells. Front Immunol. 2022;13:988125. PubMed PMID: 36131937
• Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. SARS-CoV-2 infection relaxes peripheral B cell tolerance. J Exp Med. 2022 Jun 6;219(6). PubMed PMID: 35420627
• Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan;146:110394. PubMed PMID: 33239231
• Histopathological correlation of acute on chronic eosinophilic pneumonitis caused by vaporized cannabis oil inhalation
• Lee MH, Cool CD, Maloney JP. Histopathological Correlation of Acute on Chronic Eosinophilic Pneumonitis Caused by Vaporized Cannabis Oil Inhalation. Chest. 2021 Mar;159(3):e137-e139. PubMed PMID: 33678280
• Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan;146:110394. PubMed PMID: 33239231
• Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension. Cardiovasc Res. 2020 Oct 1;116(12):2021-2030. PubMed PMID: 31710666
• Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Interstitial Macrophage-Derived Thrombospondin-1 Contributes to Hypoxia-Induced Pulmonary Hypertension. Cardiovasc Res. 2019 Nov 9. [Epub ahead of print] PubMed PMID: 31710666
• Maloney JP, Narasimhan J, Biller J. Decreased TGF-ß1 and VEGF Release in Cystic Fibrosis Platelets: Further Evidence for Platelet Defects in Cystic Fibrosis. Lung. 2016 Oct;194(5):791-8. PubMed PMID: 27423781
• Maloney JP, Gao L. Proinflammatory Cytokines Increase Vascular Endothelial Growth Factor Expression in Alveolar Epithelial Cells. Mediators Inflamm. 2015;2015:387842. PubMed PMID: 26424968

Professional Memberships

• American Thoracic Society, Member
• American College of Chest Physicians, Fellow