Philippa Marrack, PhD
Distinguished Professor, Immunology and Microbiology


  • Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 2014 Jul 3;158(1):132-42. PubMed PMID: 24995984
  • Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8553-8. PubMed PMID: 24912188
  • Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the aß T cell receptor. J Mol Med (Berl). 2014 Jul;92(7):735-41. PubMed PMID: 24848996
  • David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7735-40. PubMed PMID: 24821788
  • David A, Trigunaite A, Macleod MK, Johnson AC, Marrack P, Jørgensen TN. Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice. Genes Immun. 2014 Apr-May;15(3):153-61. PubMed PMID: 24477163
  • Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E119-28. PubMed PMID: 24344267
  • Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3216-24. PubMed PMID: 23922396
  • Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4 T cells in chronic beryllium disease. J Exp Med. 2013 Jul 1;210(7):1403-18. PubMed PMID: 23797096
  • Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. PLoS One. 2013;8(4):e61775. PubMed PMID: 23613928
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General Information

Department: Immunology and Microbiology
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Aurora, CO 80045

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