Christopher Korch, PhD

Assistant Clinical Professor, Medicine-Medical Oncology


Publications

  • Poland KS, Azim M, Folsom M, Goldfarb R, Naeem R, Korch C, Drabkin HA (TOP,CB), Gemmill RM (CB), Plon SE. A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma. Genes Chromosomes Cancer 46:805-812, 2007.
  • van Hove J, Scharer G, Spector E, Korch C, Mahieu V, Schollen E, Matthijs G, Freehauf C, Wilson C, Creadon-Swindell G, Hennermann JB (2007). Mutation spectrum in nonketotic hyperglycinemia.
  • Scharer G, van Hove J, Creadon-Swindell G, Korch C, Spector E (2007). Detection of multi-exon deletions in large genes: normalization of multiplex ligation-dependent probe amplification (MLPA) data in patients with NKH due to deletions in the GLDC gene. Presented at the annual meeting of the Association of Molecular Pathologists, November 2007. J Molecular Diagnostics 9: 655.
  • Schweppe RE, Klopper JP, Korch C, Knauf JA, Fagin JA, Marlow L, Copland JA III, Smallridge RC, Haugen BR (2008). DNA profiling analysis of human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. International Congress of Endocrinology, June 15-18, 2008, San Francisco.
  • Mouchawar J, Korch C, Pitts T, Li E, Drabkin H (TRM, CB), McCredie MRE, Giles GG, Hopper JL, Southey MC. Population-based estimate of the contribution of TP53 mutations to early-onset breast cancer: Australian Breast Cancer Family Study. Submitted.
  • Schweppe RE, Klopper JP, Korch C, Pugazhenthi U, Benezra M, Knauf JA, Fagin JA, Marlow LA, Copland JA, Smallridge RC, Haugen BR. 2008. Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. J Clin Endocrinol Metab. 93:4331-4341. Epub 2008 Aug 19.
  • Poland KS, Azim M, Folsom M, Goldfarb R, Naeem R, Korch C, Drabkin HA, Gemmill RM, Plon SE. 2007. A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma. Genes Chromosomes Cancer. 46:805-812.
  • Mouchawar J, Korch C, Byers T, Pitts T, Li E, McCredie MRE, Giles GG, Hopper JL, Southey MC. 2009. Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study. Cancer Reserch, submitted.
  • Korch C, Mouchawar J, Pitts T, Li E, McCredie MRE, Giles GG, Hopper JL, Southey MC. 2008. Novel Strategy for Comprehensive Mutation Detection in Genes: Application to a population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer in the Australian Breast Cancer Family Study. Presented at UC Denver School of Medicine, Nov 1, 2008.
  • Korch C, West J, Schweppe R, Klopper J, Haugen B, van Bokhoven A. 2008. Genetic Identification and Authentication of Cell Lines by DNA Profiling Is Critical for Valid Research Conclusions. Presented at UC Denver School of Medicine, Nov 1, 2008.
  • Korch C, West J, Schweppe R, Klopper J, Haugen J, van Bokhoven A, Ortuno LM. 2008. Genetic Identification and Authentication of Cell Lines by DNA Profiling Is Critical for Valid Research Conclusions. 1st Annual Connecticut Stem Cell Technology Symposium, September 17, 2008 in Farmington, CT.
  • Syed N, Conner A, Helfrich B, Korch C, Bekbakht K, Spillman MA. 2009. DNA genotype authentication of ovarian cancer cell lines: Provenance versus proof. Society of Gynecologic Oncologists, 40th Annual Meeting, San Antonio TX, February 2009.
  • Schweppe RE, Klopper JP, Korch C, Knauf JA, Fagin JA, Marlow LA, Copland JA, Smallridge RC, Haugen BR. 2008. DNA profiling analysis of human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. International Congress of Endocrinology June 15-18, 2008, San Francisco, CA.
  • Mouchawar J, Korch C, Pitts T, Li E, McCredie MRE, Giles GG, Hopper JL, Southey MC. 2008. Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study. Presented at Familial Cancer: Research and Practice, Melbourne, Australia, August 2008.
  • Mouchawar J, Korch C, Pitts T, Li E, McCredie MRE, Giles GG, Hopper JL, Southey MC. 2008. Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study. Presented at the Breast Cancer Family Registry: The 2nd Scientific Conference on Familial Aspects of Breast Cancer, December 10, 2008, San Antonio, TX
  • Pitts TM, Tan AC, Kulikowski GN, Tentler JJ, Brown AM, Flanigan SA, Leong S, Coldren CD, Hirsch FR, Varella-Garcia M, Korch C, Eckhardt SG. 2010. Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development. Clinical Cancer Research, in press.
  • Mouchawar J, Korch C, Byers T, Pitts TM, Li E, McCredie MRE, Giles GG, Hopper JL, Southey MC. 2010. Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study. Cancer Reserch, in press.
  • Wittenburg LA, Bisson L, Rose B, Korch C, Thamm DH. 2009. The histone deacetylase inhibitor valproic acid. Cancer Chemotherapy Pharmacology, submitted
  • Tsygankova OM, Ma C, Tang W, Korch C, Feldman MD, Lv Y. Brose MS, Meinkoth JL. 2009. Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Mol Cell Biol, submitted.
  • Syed N, Conner A, Helfrich B, Korch C, Bekbakht K, Spillman MA. 2009. DNA genotype authentication of ovarian cancer cell lines: Provenance versus proof. Society of Gynecologic Oncologists, 40th Annual Meeting, San Antonio TX, February 2009.