My research interests have involved the molecular basis of pituitary gene expression and regulation, primarily thyroid stimulating hormone (TSH), and more recently, the mechanisms underlying thyroid autoimmunity, focusing on the genetic and immunological development of disease.
Teaching
Director, Endocrine Unit, DEMS block
(2006)
School of Medicine,
Medicine
Publications
Stensland ZC, Coleman BM, Rihanek M, Baxter RM, Gottlieb PA, Hsieh EWY, Sarapura VD, Simmons KM, Cambier JC, Smith MJ. Peripheral immunophenotyping of AITD subjects reveals alterations in immune cells in pediatric vs adult-onset AITD. iScience. 2022 Jan 21;25(1):103626. PubMed PMID: 35005561
Smith MJ, Ford BR, Rihanek M, Coleman BM, Getahun A, Sarapura VD, Gottlieb PA, Cambier JC. Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity. JCI Insight. 2019 Feb 7;4(3). [Epub ahead of print] PubMed PMID: 30728334
Smith MJ, Ford BR, Rihanek M, Coleman BM, Getahun A, Sarapura VD, Gottlieb PA, Cambier JC. Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity. JCI Insight. 2019 Feb 7;4(3). [Epub ahead of print] PubMed PMID: 30728334
Smith MJ, Rihanek M, Coleman BM, Gottlieb PA, Sarapura VD, Cambier JC. Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients. J Autoimmun. 2018 May;89:82-89. PubMed PMID: 29233566
Smith MJ, Rihanek M, Coleman BM, Gottlieb PA, Sarapura VD, Cambier JC. Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients. J Autoimmun. 2017 Dec 9. [Epub ahead of print] PubMed PMID: 29233566
Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000
Hospital Affiliation
University of Colorado Hospital
Specialty Information
Specialties
Endocrinology, Diabetes and Metabolism, Board Certification (1992)
Internal Medicine, Board Certification
Conditions & Treatments
Endocrine System (Hormones)
Clinical Interests
My clinical interests include primarily thyroid, pituitary, and metabolic bone disorders, particularly abnormal thyroid function, thyroid nodules and cancer, disorders of prolactin secretion, pituitary tumors, disorders of calcium metabolism and osteoporosis.
Care Philosophy
I strive to understand the unique circumstances surrounding my patient's endocrine disorder and propose a solution that best adapts to my patient's needs.
General Information
Medical Schools:
MD, University of Buenos Aires
(1981)
Residency Programs:
Tulane University Program, Internal Medicine (1986)
Fellowships:
University of Colorado (University Hospital) Program, Endocrinology, Diabetes and Metabolism
(1990)