Stanley Szefler, MD

Professional Titles

• Director - Pediatric Asthma Research Program, Breathing Institute
• Interim Medical Director, Research Institute

Research Interests

Dr. Szefler's major contributions are directed toward the appropriate use of long-term control therapy in asthma, including the recognition of variability in response to asthma therapy. He has identified biomarkers and asthma characteristics that can be used to predict and thus individualize asthma therapy. Dr. Szefler is the Director of the Pediatric Asthma Research Program and Research Medical Director in the Breathing Institute of the Pediatric Pulmonary Section at Children's Hospital Colorado. He is also Professor of Pediatrics at the University of Colorado Denver School of Medicine. He is also a former member of the Expert Panel for the National Heart, Lung, and Blood Institute's National Asthma Education and Prevention Program on "Guidelines for the Diagnosis and Management of Asthma" and a former member of the Global Initiative for Asthma Science Committee. From 1997 through 2018 he served as Deputy Editor for the Journal of Allergy and Clinical Immunology. He has published more than 600 scientific articles and co-edited books on severe asthma, childhood asthma and pediatric allergy and immunology and personalized medicine. He is the Co-Principal Investigator for the NHLBI PrecISE Network that is focused on identifying new treatment for severe and exacerbation prone asthma. He is the Co-Principal Investigator for the NHLBI DECIPHeR Alliance that is designed to reduce health disparities by improving asthma control in disadvantaged children. For the past fifteen years, he has directed a school-based asthma program for the Denver Public School system funded by the Colorado Department of Public Health and Environment Colorado Cancer, Cardiovascular and Pulmonary Disease Program. This program seeks to define the prevalence and severity of asthma, identify those most significantly affected, and to direct those children to state of the art asthma care. The program was recently awarded a NHLBI UG3 dissemination and implementation grant (DECIPHeR) to assess the feasibility of extending the school-centered asthma program to 5 regional hubs in Colorado.

Publications

• Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: Knowledge gaps in childhood asthma. J Allergy Clin Immunol. 2014 Jan;133(1):3-13. PubMed PMID: 24290281
• Szefler SJ, Carlsson LG, Uryniak T, Baker JW. Budesonide inhalation suspension versus montelukast in children aged 2 to 4 years with mild persistent asthma. J Allergy Clin Immunol Pract. 2013 Jan;1(1):58-64. PubMed PMID: 24229823
• Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ, on behalf of the Childhood Asthma Research and Education (CARE) Network Investigators. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2013 Oct 15. [Epub ahead of print] PubMed PMID: 24139497
• Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF Jr, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov;132(5):1068-1074.e1. PubMed PMID: 24084072
• Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF Jr, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol. 2013 Sep 28. [Epub ahead of print] PubMed PMID: 24084071
• Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013 Aug 28;14:86. PubMed PMID: 23984888
• Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug;132(2):313-20.e15. PubMed PMID: 23541324
• Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013;8(2):e56179. PubMed PMID: 23457522
• Raissy HH, Kelly HW, Harkins M, Szefler SJ. Inhaled corticosteroids in lung diseases. Am J Respir Crit Care Med. 2013 Apr 15;187(8):798-803. PubMed PMID: 23370915
• Szefler SJ. Advances in pediatric asthma in 2012: moving toward asthma prevention. J Allergy Clin Immunol. 2013 Jan;131(1):36-46. PubMed PMID: 23199603
• Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF Jr, NHLBI Asthma Clinical Research Network Investigators. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 1;187(1):28-33. PubMed PMID: 23144325
• Tamesis GP, Covar RA, Strand M, Liu AH, Szefler SJ, Klinnert MD. Predictors for asthma at age 7 years for low-income children enrolled in the Childhood Asthma Prevention Study. J Pediatr. 2013 Mar;162(3):536-542.e2. PubMed PMID: 23036483
• Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: Knowledge gaps in childhood asthma. J Allergy Clin Immunol 2014;133:3-13 PMID 24290281 PMC3925634
• Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF, Guilbert TW, Zeiger RS, Bacherier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol 2014;133:350-6. PMID 24084071 PMC3960329
• Cicutto L, Gleason M, Szefler SJ. Establishing school-centered asthma programs. J Allergy Clin Immunol. 2014 Dec;134(6):1223-1230. PubMed PMID: 25482867
• Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of Airway Microbiota and Inflammation in Cystic Fibrosis Using Multiple Sampling Methods. Ann Am Thorac Soc. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25474078
• Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2014 Nov 8. [Epub ahead of print] PubMed PMID: 25458797
• Long A, Rothman K, Chen H, Carrigan G, Szefler S, EXCELS study authors. Reply. J Allergy Clin Immunol. 2014 Oct 29. [Epub ahead of print] PubMed PMID: 25441293
• Meltzer LJ, Ullrich M, Szefler SJ. Sleep duration, sleep hygiene, and insomnia in adolescents with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):562-9. PubMed PMID: 25213049
• Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA. A genome-wide survey of CD4( ) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. PubMed PMID: 24934276
• Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF Jr, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug;134(2):483-5. PubMed PMID: 24835502
• Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Reply: To PMID 24290281. J Allergy Clin Immunol. 2014 Jun;133(6):1776-7. PubMed PMID: 24786239
• Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB, Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute. The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing. J Allergy Clin Immunol. 2014 May;133(5):1489-92, 1492.e1-3. PubMed PMID: 24698320
• Long A, Rahmaoui A, Rothman KJ, Guinan E, Eisner M, Bradley MS, Iribarren C, Chen H, Carrigan G, Rosén K, Szefler SJ. Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab. J Allergy Clin Immunol. 2014 Sep;134(3):560-567.e4. PubMed PMID: 24679845
• Szefler SJ. Advances in pediatric asthma in 2013: coordinating asthma care. J Allergy Clin Immunol. 2014 Mar;133(3):654-61. PubMed PMID: 24581430
• Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar;133(3):664-9.e5. PubMed PMID: 24486069
• Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ, Childhood Asthma Research and Education (CARE) Network Investigators. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2014 Feb;133(2):363-9. PubMed PMID: 24139497
• Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Oct 23. [Epub ahead of print] PubMed PMID: 26518090
• Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Oct 20;16:128. PubMed PMID: 26487277
• Spahn JD, Malka J, Szefler SJ. Current Application of Exhaled Nitric Oxide in Clinical Practice. J Allergy Clin Immunol. 2016 Sep 21. [Epub ahead of print] PubMed PMID: 27664377
• Leung DY, Szefler SJ. The Editors' Choice. J Allergy Clin Immunol. 2015 Oct;136(4):872-3. PubMed PMID: 26449800
• Iribarren C, Rahmaoui A, Long AA, Szefler SJ, Bradley MS, Carrigan G, Eisner MD, Chen H, Omachi TA, Farkouh ME, Rothman KJ. Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study of moderate-to-severe asthma. J Allergy Clin Immunol. 2016 Sep 14. [Epub ahead of print] PubMed PMID: 27639934
• Lemanske RF Jr, Kakumanu S, Shanovich K, Antos N, Cloutier MM, Mazyck D, Phipatanakul W, Schantz S, Szefler S, Vandlik R, Williams P. Creation and implementation of SAMPRO™: A school-based asthma management program. J Allergy Clin Immunol. 2016 Sep;138(3):711-23. PubMed PMID: 27596707
• Leung DY, Szefler SJ. The Editors' Choice. J Allergy Clin Immunol. 2015 Sep;136(3):569-70. PubMed PMID: 26343940
• Anderson WC 3rd, Szefler SJ. New and future strategies to improve asthma control in children. J Allergy Clin Immunol. 2015 Oct;136(4):848-59. PubMed PMID: 26318072
• Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma: An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Aug 25. [Epub ahead of print] PubMed PMID: 26305520
• Stempel DA, Szefler SJ, Pedersen S, Zeiger RS, Yeakey AM, Lee LA, Liu AH, Mitchell H, Kral KM, Raphiou IH, Prillaman BA, Buaron KS, Yun Kirby S, Pascoe SJ. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Sep 1;375(9):840-9. PubMed PMID: 27579634
• Reddel HK, Bateman ED, Becker A, Boulet LP, Cruz AA, Drazen JM, Haahtela T, Hurd SS, Inoue H, de Jongste JC, Lemanske RF Jr, Levy ML, O'Byrne PM, Paggiaro P, Pedersen SE, Pizzichini E, Soto-Quiroz M, Szefler SJ, Wong GW, FitzGerald JM. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J. 2015 Sep;46(3):622-39. PubMed PMID: 26206872
• Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18;375(7):619-30. PubMed PMID: 27532828
• Liu AH, Anderson WC 3rd, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 Aug;138(2):397-404. PubMed PMID: 27497278
• Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 1;192(5):551-8. PubMed PMID: 26068329
• Brand PL, Mäkelä MJ, Szefler SJ, Frischer T, Price D. Monitoring asthma in childhood: symptoms, exacerbations and quality of life. Eur Respir Rev. 2015 Jun;24(136):187-93. PubMed PMID: 26028631
• Federico MJ, Hoch HE, Anderson WC 3rd, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 Aug;63(1):103-26. PubMed PMID: 27426897
• Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW. Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings. Pediatr Pulmonol. 2015 Apr 14. [Epub ahead of print] PubMed PMID: 25872769
• McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST. Genetics and Genomics of Longitudinal Lung Function Patterns in Asthmatics. Am J Respir Crit Care Med. 2016 Jul 1. [Epub ahead of print] PubMed PMID: 27367781
• Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Feb 7;16:20. PubMed PMID: 25851298
• Liptzin DR, Gleason MC, Cicutto LC, Cleveland CL, Shocks DJ, White MK, Faino AV, Szefler SJ. Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program. J Allergy Clin Immunol Pract. 2016 Sep-Oct;4(5):972-979.e1. PubMed PMID: 27283054
• McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12;374(19):1842-52. PubMed PMID: 27168434
• Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA. DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S99-S100. PubMed PMID: 27027970
• Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S23-4. PubMed PMID: 27027947
• Dunn R, Szefler SJ. Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S103-4. PubMed PMID: 27027942
• Teach SJ, Gergen PJ, Szefler SJ, Mitchell HE, Calatroni A, Wildfire J, Bloomberg GR, Kercsmar CM, Liu AH, Makhija MM, Matsui E, Morgan W, O'Connor G, Busse WW. Seasonal risk factors for asthma exacerbations among inner-city children. J Allergy Clin Immunol. 2015 Jun;135(6):1465-73.e5. PubMed PMID: 25794658
• Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL. Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial. J Allergy Clin Immunol. 2016 Aug;138(2):441-450.e8. PubMed PMID: 26960245
• Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF Jr, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):540-6.e3. PubMed PMID: 25783161
• Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2015;6:5. PubMed PMID: 26862389
• Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul;136(1):69-80. PubMed PMID: 25769910
• Szefler SJ. Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies. Allergy Asthma Proc. 2016 Jan-Feb;37(1):4-8. PubMed PMID: 26831839
• Cicutto L, Shocks D, Gleason M, Haas-Howard C, White M, Szefler SJ. Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study. NASN Sch Nurse. 2016 Mar;31(2):112-8. PubMed PMID: 26822131
• Bender BG, Krishnan JA, Chambers DA, Cloutier MM, Riekert KA, Rand CS, Schatz M, Thomson CC, Wilson SR, Apter A, Carson SS, George M, Gerald JK, Gerald L, Goss CH, Okelo SO, Mularski RA, Nguyen HQ, Patel MR, Szefler SJ, Weiss CH, Wilson KC, Freemer M. American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report. Ann Am Thorac Soc. 2015 Dec;12(12):S213-21. PubMed PMID: 26653201
• Pijnenburg MW, Baraldi E, Brand PL, Carlsen KH, Eber E, Frischer T, Hedlin G, Kulkarni N, Lex C, Mäkelä MJ, Mantzouranis E, Moeller A, Pavord I, Piacentini G, Price D, Rottier BL, Saglani S, Sly PD, Szefler SJ, Tonia T, Turner S, Wooler E, Lødrup Carlsen KC. Monitoring asthma in children. Eur Respir J. 2015 Apr;45(4):906-25. PubMed PMID: 25745042
• Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CA, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17;314(19):2034-44. PubMed PMID: 26575060
• Szefler SJ. Advances in pediatric asthma in 2014: Moving toward a population health perspective. J Allergy Clin Immunol. 2015 Mar;135(3):644-52. PubMed PMID: 25649079
• Szefler SJ. Monitoring and adherence in asthma management. Lancet Respir Med. 2015 Mar;3(3):175-6. PubMed PMID: 25617214
• Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct;15(5):422-9. PubMed PMID: 25601762
• Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ß2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. PubMed PMID: 25562107
• Cicutto L, Gleason M, Szefler SJ. Establishing school-centered asthma programs. J Allergy Clin Immunol. 2014 Dec;134(6):1223-30; quiz 1231. PubMed PMID: 25482867
• Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of airway microbiota and inflammation in cystic fibrosis using multiple sampling methods. Ann Am Thorac Soc. 2015 Feb;12(2):221-9. PubMed PMID: 25474078
• Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2015 Mar;16(2):101-7. PubMed PMID: 25458797
• Hoch HE, Szefler SJ. Intermittent steroid inhalation for the treatment of childhood asthma. Expert Rev Clin Immunol. 2016;12(2):183-94. PubMed PMID: 26561351
• Long A, Rothman K, Chen H, Carrigan G, Szefler S. Reply: To PMID 24679845. J Allergy Clin Immunol. 2015 Jan;135(1):289-90. PubMed PMID: 25441293
• Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Dec;136(6):1476-85. PubMed PMID: 26518090
• Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Oct 20;16:128. PubMed PMID: 26487277
• Anderson WC 3rd, Szefler SJ. New and future strategies to improve asthma control in children. J Allergy Clin Immunol. 2015 Oct;136(4):848-59. PubMed PMID: 26318072
• Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1366-72. PubMed PMID: 26305520
• Reddel HK, Bateman ED, Becker A, Boulet LP, Cruz AA, Drazen JM, Haahtela T, Hurd SS, Inoue H, de Jongste JC, Lemanske RF Jr, Levy ML, O'Byrne PM, Paggiaro P, Pedersen SE, Pizzichini E, Soto-Quiroz M, Szefler SJ, Wong GW, FitzGerald JM. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J. 2015 Sep;46(3):622-39. PubMed PMID: 26206872
• Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 1;192(5):551-8. PubMed PMID: 26068329
• Meltzer LJ, Ullrich M, Szefler SJ. Sleep duration, sleep hygiene, and insomnia in adolescents with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):562-9. PubMed PMID: 25213049
• Brand PL, Mäkelä MJ, Szefler SJ, Frischer T, Price D. Monitoring asthma in childhood: symptoms, exacerbations and quality of life. Eur Respir Rev. 2015 Jun;24(136):187-93. PubMed PMID: 26028631
• Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW. Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings. Pediatr Pulmonol. 2015 Dec;50(12):1360-7. PubMed PMID: 25872769
• Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA. A genome-wide survey of CD4( ) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. PubMed PMID: 24934276
• Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Feb 7;16:20. PubMed PMID: 25851298
• Teach SJ, Gergen PJ, Szefler SJ, Mitchell HE, Calatroni A, Wildfire J, Bloomberg GR, Kercsmar CM, Liu AH, Makhija MM, Matsui E, Morgan W, O'Connor G, Busse WW. Seasonal risk factors for asthma exacerbations among inner-city children. J Allergy Clin Immunol. 2015 Jun;135(6):1465-73.e5. PubMed PMID: 25794658
• Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF Jr, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):540-6.e3. PubMed PMID: 25783161
• Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul;136(1):69-80. PubMed PMID: 25769910
• Green AW, Goldstein S, Szefler SJ, Wanderer A, Weinberger M. In lasting tribute: Elliot F. Ellis, MD, 1929-2014. J Allergy Clin Immunol. 2014 May;133(5):1504-5. PubMed PMID: 24892145
• Pijnenburg MW, Baraldi E, Brand PL, Carlsen KH, Eber E, Frischer T, Hedlin G, Kulkarni N, Lex C, Mäkelä MJ, Mantzouranis E, Moeller A, Pavord I, Piacentini G, Price D, Rottier BL, Saglani S, Sly PD, Szefler SJ, Tonia T, Turner S, Wooler E, Lødrup Carlsen KC. Monitoring asthma in children. Eur Respir J. 2015 Apr;45(4):906-25. PubMed PMID: 25745042
• Szefler SJ. Advances in pediatric asthma in 2014: Moving toward a population health perspective. J Allergy Clin Immunol. 2015 Mar;135(3):644-52. PubMed PMID: 25649079
• Szefler SJ. Monitoring and adherence in asthma management. Lancet Respir Med. 2015 Mar;3(3):175-6. PubMed PMID: 25617214
• Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct;15(5):422-9. PubMed PMID: 25601762
• Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ß2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. PubMed PMID: 25562107
• Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF Jr, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug;134(2):483-5. PubMed PMID: 24835502
• Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of airway microbiota and inflammation in cystic fibrosis using multiple sampling methods. Ann Am Thorac Soc. 2015 Feb;12(2):221-9. PubMed PMID: 25474078
• Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2015 Mar;16(2):101-7. PubMed PMID: 25458797
• Long A, Rothman K, Chen H, Carrigan G, Szefler S. Reply: To PMID 24679845. J Allergy Clin Immunol. 2015 Jan;135(1):289-90. PubMed PMID: 25441293
• Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Reply: To PMID 24290281. J Allergy Clin Immunol. 2014 Jun;133(6):1776-7. PubMed PMID: 24786239
• Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB. The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing. J Allergy Clin Immunol. 2014 May;133(5):1489-92, 1492.e1-3. PubMed PMID: 24698320
• Long A, Rahmaoui A, Rothman KJ, Guinan E, Eisner M, Bradley MS, Iribarren C, Chen H, Carrigan G, Rosén K, Szefler SJ. Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab. J Allergy Clin Immunol. 2014 Sep;134(3):560-567.e4. PubMed PMID: 24679845
• Szefler SJ. Advances in pediatric asthma in 2013: coordinating asthma care. J Allergy Clin Immunol. 2014 Mar;133(3):654-61. PubMed PMID: 24581430
• Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar;133(3):664-9.e5. PubMed PMID: 24486069
• Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 2014 Jan;133(1):3-13; quiz 14. PubMed PMID: 24290281
• Szefler SJ. Author's response. Ann Allergy Asthma Immunol. 2017 Aug;119(2):194. PubMed PMID: 28801018
• Chipps BE, Haselkorn T, Paknis B, Ortiz B, Bleecker ER, Kianifard F, Foreman AJ, Szefler SJ, Zeiger RS. More than a decade follow-up in patients with severe or difficult-to-treat asthma: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) II. J Allergy Clin Immunol. 2017 Aug 7. [Epub ahead of print] PubMed PMID: 28797732
• Fitzpatrick AM, Jackson DJ, Mauger D, Szefler SJ. Reply. J Allergy Clin Immunol. 2017 Aug 3. [Epub ahead of print] PubMed PMID: 28780972
• Abrams EM, Szefler SJ, Becker AB. Does inhaled steroid therapy help emerging asthma in early childhood?. Lancet Respir Med. 2017 Aug 2. [Epub ahead of print] PubMed PMID: 28780183
• Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2014 Feb;133(2):363-9. PubMed PMID: 24139497
• Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF Jr, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol. 2014 Feb;133(2):350-6. PubMed PMID: 24084071
• Anderson WC 3rd, Apter AJ, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma in 2016: Designing individualized approaches to management. J Allergy Clin Immunol. 2017 Sep;140(3):671-680. PubMed PMID: 28709967
• Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE. Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma. Am J Respir Crit Care Med. 2017 Jun 13. [Epub ahead of print] PubMed PMID: 28608756
• Chipps BE, Lanier B, Milgrom H, Deschildre A, Hedlin G, Szefler SJ, Kattan M, Kianifard F, Ortiz B, Haselkorn T, Iqbal A, Rosén K, Trzaskoma B, Busse WW. Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience. J Allergy Clin Immunol. 2017 May;139(5):1431-1444. PubMed PMID: 28477722
• Hamelmann E, Vogelberg C, Szefler SJ. Reply to 'Can a better patient phenotyping predict the efficacy of tiotropium in asthmatic adolescents?'. Expert Opin Pharmacother. 2017 Jun;18(8):837-838. PubMed PMID: 28399660
• Hoch HE, Calatroni A, West JB, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Kim H, Lamm CI, Makhija MM, Mitchell HE, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ. Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index. J Allergy Clin Immunol. 2017 Feb 24. [Epub ahead of print] PubMed PMID: 28238748
• Bacharier LB, Szefler SJ. Pediatric asthma - moving ahead faster than ever. Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):96-98. PubMed PMID: 28225363
• Szefler SJ, Murphy K, Harper T 3rd, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E. A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma. J Allergy Clin Immunol. 2017 Feb 9. [Epub ahead of print] PubMed PMID: 28189771
• Kakumanu S, Antos N, Szefler SJ, Lemanske RF Jr. Building school health partnerships to improve pediatric asthma care: the School-based Asthma Management Program. Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):160-166. PubMed PMID: 28177950
• Bacharier LB, Szefler SJ. Editorial: moving ahead faster than ever. Curr Opin Allergy Clin Immunol. 2017 Jan 30. [Epub ahead of print] PubMed PMID: 28141627
• Hamelmann E, Vogelberg C, Szefler SJ. Tiotropium for the treatment of asthma in adolescents. Expert Opin Pharmacother. 2017 Feb;18(3):305-312. PubMed PMID: 28110558
• Burbank AJ, Szefler SJ. Current and future management of the young child with early onset wheezing. Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):146-152. PubMed PMID: 28092287
• Abrams EM, Szefler SJ, Becker AB. Effect of asthma therapies on the natural course of asthma. Ann Allergy Asthma Immunol. 2016 Dec;117(6):627-633. PubMed PMID: 28073701
• Nyenhuis SM, Krishnan JA, Berry A, Calhoun WJ, Chinchilli VM, Engle L, Grossman N, Holguin F, Israel E, Kittles RA, Kraft M, Lazarus SC, Lehman EB, Mauger DT, Moy JN, Peters SP, Phipatanakul W, Smith LJ, Sumino K, Szefler SJ, Wechsler ME, Wenzel S, White SR, Ackerman SJ. Race is associated with differences in airway inflammation in patients with asthma. J Allergy Clin Immunol. 2017 Jul;140(1):257-265.e11. PubMed PMID: 28069248
• Carr WW, Szefler SJ. Inhaled corticosteroids: Ocular safety and the hypothalamic-pituitary-adrenal axis. Ann Allergy Asthma Immunol. 2016 Dec;117(6):589-594. PubMed PMID: 27979014
• Stempel DA, Szefler SJ, Pascoe SJ. Salmeterol and Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Dec 1;375(22):e46. PubMed PMID: 27959746
• Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol. 2016 Dec;138(6):1608-1618.e12. PubMed PMID: 27777180
• Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA. The nasal methylome and childhood atopic asthma. J Allergy Clin Immunol. 2017 May;139(5):1478-1488. PubMed PMID: 27745942
• Liptzin DR, Szefler SJ. Evolution of Asthma Self-Management Programs in Adolescents: From the Crisis Plan to Facebook. J Pediatr. 2016 Dec;179:19-23. PubMed PMID: 27745749
• Gleason M, Cicutto L, Haas-Howard C, Raleigh BM, Szefler SJ. Leveraging Partnerships: Families, Schools, and Providers Working Together to Improve Asthma Management. Curr Allergy Asthma Rep. 2016 Oct;16(10):74. PubMed PMID: 27709456
• Spahn JD, Malka J, Szefler SJ. Current application of exhaled nitric oxide in clinical practice. J Allergy Clin Immunol. 2016 Nov;138(5):1296-1298. PubMed PMID: 27664377
• Iribarren C, Rahmaoui A, Long AA, Szefler SJ, Bradley MS, Carrigan G, Eisner MD, Chen H, Omachi TA, Farkouh ME, Rothman KJ. Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma. J Allergy Clin Immunol. 2017 May;139(5):1489-1495.e5. PubMed PMID: 27639934
• Lemanske RF Jr, Kakumanu S, Shanovich K, Antos N, Cloutier MM, Mazyck D, Phipatanakul W, Schantz S, Szefler S, Vandlik R, Williams P. Creation and implementation of SAMPRO™: A school-based asthma management program. J Allergy Clin Immunol. 2016 Sep;138(3):711-723. PubMed PMID: 27596707
• Stempel DA, Szefler SJ, Pedersen S, Zeiger RS, Yeakey AM, Lee LA, Liu AH, Mitchell H, Kral KM, Raphiou IH, Prillaman BA, Buaron KS, Yun Kirby S, Pascoe SJ. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Sep 1;375(9):840-9. PubMed PMID: 27579634
• Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18;375(7):619-30. PubMed PMID: 27532828
• Liu AH, Anderson WC 3rd, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 Aug;138(2):397-404. PubMed PMID: 27497278
• Federico MJ, Hoch HE, Anderson WC 3rd, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 Aug;63(1):103-26. PubMed PMID: 27426897
• McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST. Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. Am J Respir Crit Care Med. 2016 Dec 15;194(12):1465-1474. PubMed PMID: 27367781
• Liptzin DR, Gleason MC, Cicutto LC, Cleveland CL, Shocks DJ, White MK, Faino AV, Szefler SJ. Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program. J Allergy Clin Immunol Pract. 2016 Sep-Oct;4(5):972-979.e1. PubMed PMID: 27283054
• McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12;374(19):1842-1852. PubMed PMID: 27168434
• Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA. DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S99-S100. PubMed PMID: 27027970
• Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S23-4. PubMed PMID: 27027947
• Dunn R, Szefler SJ. Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S103-4. PubMed PMID: 27027942
• Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL. Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial. J Allergy Clin Immunol. 2016 Aug;138(2):441-450.e8. PubMed PMID: 26960245
• Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2015;6:5. PubMed PMID: 26862389
• Szefler SJ. Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies. Allergy Asthma Proc. 2016 Jan-Feb;37(1):4-8. PubMed PMID: 26831839
• Cicutto L, Shocks D, Gleason M, Haas-Howard C, White M, Szefler SJ. Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study. NASN Sch Nurse. 2016 Mar;31(2):112-8. PubMed PMID: 26822131
• Hoch HE, Szefler SJ. Intermittent steroid inhalation for the treatment of childhood asthma. Expert Rev Clin Immunol. 2016;12(2):183-94. PubMed PMID: 26561351
• Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Erratum to: Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2017;7:32. PubMed PMID: 28932386
• Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. J Allergy Clin Immunol Pract. 2018 Sep 26. [Epub ahead of print] PubMed PMID: 30267890
• Abrams EM, Becker AB, Szefler SJ. Use of Oral Corticosteroids in the Wheezy Toddler. J Pediatr. 2018 Oct;201:16-20. PubMed PMID: 30251636
• Szefler SJ, Hoch H, Tuffli M, Gondalia R, Barrett MA, Van Sickle D, Stempel DA. Quantifying beta agonist utilization: occasions or puffs?. J Allergy Clin Immunol Pract. 2018 Sep 12. [Epub ahead of print] PubMed PMID: 30218718
• Guilbert T, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Racial Disparities in Asthma-Related Health Outcomes in Children with Severe/Difficult-to-Treat Asthma. J Allergy Clin Immunol Pract. 2018 Aug 29. [Epub ahead of print] PubMed PMID: 30172020
• Hollenbach J, Villarreal M, Simoneau T, Langton C, Mitchell H, Flores G, M Cloutier M, Szefler S. Inaccuracy of asthma-related self-reported health-care utilization data compared to Medicaid claims. J Asthma. 2018 Sep 25;:1-4. [Epub ahead of print] PubMed PMID: 30091938
• Szefler SJ, Cloutier MM, Villarreal M, Hollenbach JP, Gleason M, Haas-Howard C, Vinick C, Calatroni A, Cicutto L, White M, Williams S, McGinn M, Langton C, Shocks D, Mitchell H, Stempel DA. Building Bridges for Asthma Care: Reducing school absence for inner-city children with health disparities. J Allergy Clin Immunol. 2018 Jul 25. [Epub ahead of print] PubMed PMID: 30055181
• Szefler SJ. Boehringer-Ingelheim Satellite Symposium Choosing the Right Controller Therapy in Pediatric Patients with Asthma. Pediatr Pulmonol. 2018 Jun;53(S1):S171-S173. PubMed PMID: 29906344
• Messinger AI, Deterding RR, Szefler SJ. Bringing Technology to Day-to-Day Asthma Management. Am J Respir Crit Care Med. 2018 Aug 1;198(3):291-292. PubMed PMID: 29847147
• Szefler SJ. Dr Elliot F. Ellis: Initiating personalized asthma management in children. Ann Allergy Asthma Immunol. 2018 Jul;121(1):3-6. PubMed PMID: 29758291
• Chipps BE, Bacharier LB, Farrar JR, Jackson DJ, Murphy KR, Phipatanakul W, Szefler SJ, Teague WG, Zeiger RS. The pediatric asthma yardstick: Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Ann Allergy Asthma Immunol. 2018 Jun;120(6):559-579.e11. PubMed PMID: 29653238
• Hoch H, Kempe A, Brinton J, Szefler S. Feasibility of medication monitoring sensors in high risk asthmatic children. J Asthma. 2018 Apr 11;:1-3. [Epub ahead of print] PubMed PMID: 29641374
• Szefler SJ. Asthma across the lifespan: Time for a paradigm shift. J Allergy Clin Immunol. 2018 Sep;142(3):773-780. PubMed PMID: 29627424
• Szefler SJ, Chipps B. Challenges in the treatment of asthma in children and adolescents. Ann Allergy Asthma Immunol. 2018 Apr;120(4):382-388. PubMed PMID: 29625664
• Morris CR, Mauger DT, Suh JH, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Szefler SJ, Jackson DJ, Fitzpatrick AM. Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?. J Allergy Clin Immunol. 2018 Jul;142(1):308-311.e9. PubMed PMID: 29518418
• Anderson WC 3rd, Szefler SJ. Controlling the Risk Domain in Pediatric Asthma through Personalized Care. Semin Respir Crit Care Med. 2018 Feb;39(1):36-44. PubMed PMID: 29427984
• Hamelmann E, Szefler SJ. Efficacy and Safety of Tiotropium in Children and Adolescents. Drugs. 2018 Mar;78(3):327-338. PubMed PMID: 29368127
• Vrijlandt EJLE, El Azzi G, Vandewalker M, Rupp N, Harper T, Graham L, Szefler SJ, Moroni-Zentgraf P, Sharma A, Vulcu SD, Sigmund R, Chawes B, Engel M, Bisgaard H. Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2018 Feb;6(2):127-137. PubMed PMID: 29361462
• Lang JE, Fitzpatrick AM, Mauger DT, Guilbert TW, Jackson DJ, Lemanske RF Jr, Martinez FD, Strunk RC, Zeiger RS, Phipatanakul W, Bacharier LB, Pongracic JA, Holguin F, Cabana MD, Covar RA, Raissy HH, Tang M, Szefler SJ. Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids. J Allergy Clin Immunol. 2018 Apr;141(4):1459-1467.e2. PubMed PMID: 29273557
• Anderson WC 3rd, Gleason MC, Miyazawa N, Szefler SJ. Approaching Current and New Drug Therapies for Pediatric Asthma. Pediatr Clin North Am. 2017 Dec;64(6):1197-1207. PubMed PMID: 29173780
• Snieder HM, Nickels S, Gleason M, McFarlane A, Szefler SJ, Allison MA. Stakeholder Perspectives on Optimizing Communication in a School-Centered Asthma Program. J Sch Health. 2017 Dec;87(12):941-948. PubMed PMID: 29096412
• Chipps BE, Haselkorn T, Paknis B, Ortiz B, Bleecker ER, Kianifard F, Foreman AJ, Szefler SJ, Zeiger RS. More than a decade follow-up in patients with severe or difficult-to-treat asthma: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) II. J Allergy Clin Immunol. 2018 May;141(5):1590-1597.e9. PubMed PMID: 28797732
• Fitzpatrick AM, Jackson DJ, Mauger D, Szefler SJ. Reply. J Allergy Clin Immunol. 2017 Oct;140(4):1213. PubMed PMID: 28780972
• Abrams EM, Szefler SJ, Becker AB. Does inhaled steroid therapy help emerging asthma in early childhood?. Lancet Respir Med. 2017 Oct;5(10):827-834. PubMed PMID: 28780183
• Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE. Effects of Omalizumab on Rhinovirus Infections, Illnesses, and Exacerbations of Asthma. Am J Respir Crit Care Med. 2017 Oct 15;196(8):985-992. PubMed PMID: 28608756
• Chipps BE, Lanier B, Milgrom H, Deschildre A, Hedlin G, Szefler SJ, Kattan M, Kianifard F, Ortiz B, Haselkorn T, Iqbal A, Rosén K, Trzaskoma B, Busse WW. Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience. J Allergy Clin Immunol. 2017 May;139(5):1431-1444. PubMed PMID: 28477722
• Hoch HE, Calatroni A, West JB, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Kim H, Lamm CI, Makhija MM, Mitchell HE, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ. Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index. J Allergy Clin Immunol. 2017 Oct;140(4):1130-1137.e5. PubMed PMID: 28238748
• Szefler SJ, Murphy K, Harper T 3rd, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E. A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma. J Allergy Clin Immunol. 2017 Nov;140(5):1277-1287. PubMed PMID: 28189771
• Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NN. Development and Initial Validation of the Asthma Severity Scoring System (ASSESS). J Allergy Clin Immunol. 2019 Oct 8. [Epub ahead of print] PubMed PMID: 31604088
• Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF Jr, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E. Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma. N Engl J Med. 2019 Sep 26;381(13):1227-1239. PubMed PMID: 31553835
• Szefler SJ. Legends of allergy and immunology: Donald Y. M. Leung. Allergy. 2019 Aug 29. [Epub ahead of print] PubMed PMID: 31465550
• Barnes PJ, Szefler SJ, Reddel HK, Chipps BE. Symptoms and perception of airway obstruction in asthmatic patients: Clinical implications for use of reliever medications. J Allergy Clin Immunol. 2019 Jul 19. [Epub ahead of print] PubMed PMID: 31330221
• Graham LM, Kerstjens HAM, Vogelberg C, Hamelmann E, Szefler SJ, Pisternick-Ruf W, Engel M, El Azzi G, Unseld A, Foggs MB. Safety of tiotropium Respimat(®) in black or African-American patients with symptomatic asthma. Respir Med. 2019 Aug;155:58-60. PubMed PMID: 31302579
• Fielding S, Pijnenburg M, de Jongste JC, Pike KC, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. Response. Chest. 2019 Jun;155(6):1313-1314. PubMed PMID: 31174655
• Lee LA, Pedersen S, Pascoe SJ, Szefler SJ, Lenney W. No dose effect observed with chronic fluticasone propionate on growth velocity in children. Pediatr Allergy Immunol. 2020 Sep 23. [Epub ahead of print] PubMed PMID: 32966707
• Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, Billheimer D, Bleecker ER, Cardet JC, Castro M, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Holguin F, Jain S, Kenyon NJ, Krishnan JA, Kraft M, Kumar R, Liu MC, Ly NP, Moy JN, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Wechsler ME, Wenzel SE, White SR. The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations. J Biopharm Stat. 2020 Sep 17;:1-12. [Epub ahead of print] PubMed PMID: 32941098
• Kaplan A, Szefler SJ, Halpin DMG. Impact of comorbid conditions on asthmatic adults and children. NPJ Prim Care Respir Med. 2020 Aug 20;30(1):36. PubMed PMID: 32820164
• Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Harada N, Atsuta R, Fujisawa T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez FD, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in asthma: practical considerations. Eur Respir J. 2020 Aug;56(2). PubMed PMID: 32820024
• Navanandan N, Hamlington KL, Mistry RD, Szefler SJ, Liu AH. Oscillometry for acute asthma in the pediatric emergency department: A feasibility study. Ann Allergy Asthma Immunol. 2020 Jul 9. [Epub ahead of print] PubMed PMID: 32652127
• Abrams EM, Szefler SJ. COVID-19 and the impact of social determinants of health. Lancet Respir Med. 2020 Jul;8(7):659-661. PubMed PMID: 32437646
• Szefler SJ, Goldstein S, Vogelberg C, Bensch GW, Given J, Jugovic B, Engel M, Moroni-Zentgraf PM, Sigmund R, Hamelmann EH. Forced Expiratory Flow (FEF(25-75%)) as a Clinical Endpoint in Children and Adolescents with Symptomatic Asthma Receiving Tiotropium: A Post Hoc Analysis. Pulm Ther. 2020 May 12. [Epub ahead of print] PubMed PMID: 32399899
• Abrams EM, Szefler SJ. Managing Asthma during Coronavirus Disease-2019: An Example for Other Chronic Conditions in Children and Adolescents. J Pediatr. 2020 Jul;222:221-226. PubMed PMID: 32330469
• Szefler SJ, Casale TB, Haselkorn T, Yoo B, Ortiz B, Kattan M, Busse WW. Treatment Benefit with Omalizumab in Children by Indicators of Asthma Severity. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2673-2680.e3. PubMed PMID: 32298853
• Guilbert TW, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Reply. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):2102-2103. PubMed PMID: 31122886
• Cotter JM, Tyler A, Reese J, Ziniel S, Federico MJ, Anderson Iii WC, Kupfer O, Szefler SJ, Kerby G, Hoch HE. Steroid variability in pediatric inpatient asthmatics: survey on provider preferences of dexamethasone versus prednisone. J Asthma. 2019 Jun 12;:1-7. [Epub ahead of print] PubMed PMID: 31113252
• Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF Jr, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 May 23;380(21):2009-2019. PubMed PMID: 31112384
• Vogelberg C, Szefler SJ, Vrijlandt EJLE, Boner AL, Engel M, El Azzi G, Vulcu SD, Moroni-Zentgraf PM, Eickmeier O, Hamelmann EH. Tiotropium add-on therapy is safe and reduces seasonal worsening in paediatric asthma patients. Eur Respir J. 2019 Jun;53(6). PubMed PMID: 31097514
• Szefler SJ, Raphiou I, Zeiger RS, Stempel D, Kral K, Pascoe S. Seasonal variation in asthma exacerbations in the AUSTRI and VESTRI studies. ERJ Open Res. 2019 Apr;5(2). PubMed PMID: 31086795
• Mosnaim G, Stempel H, Szefler SJ, Stempel DA. Asthma Control-Time to Rethink Definitions and Criteria. J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1522-1523. PubMed PMID: 31076062
• Hamelmann E, Szefler SJ, Lau S. Severe asthma in children and adolescents. Allergy. 2019 May 10. [Epub ahead of print] PubMed PMID: 31074873
• Federico MJ, McFarlane AE 2nd, Szefler SJ, Abrams EM. The Impact of Social Determinants of Health on Children with Asthma. J Allergy Clin Immunol Pract. 2020 Jun;8(6):1808-1814. PubMed PMID: 32294541
• Halpin DMG, Hamelmann EH, Frith PA, Moroni-Zentgraf PM, van Hecke B, Unseld A, Kerstjens HAM, Szefler SJ. Comparative Responses in Lung Function Measurements with Tiotropium in Adolescents and Adults, and Across Asthma Severities: A Post Hoc Analysis. Pulm Ther. 2020 Jun;6(1):131-140. PubMed PMID: 32180164
• Federico MJ, Szefler SJ. High-risk asthma: Never give up. Ann Allergy Asthma Immunol. 2019 May;122(5):441-442. PubMed PMID: 31054649
• Haselkorn T, Szefler SJ, Chipps BE, Bleecker ER, Harkins MS, Paknis B, Kianifard F, Ortiz B, Zeiger RS. Disease Burden and Long-Term Risk of Persistent Very Poorly Controlled Asthma: TENOR II. J Allergy Clin Immunol Pract. 2020 Jul - Aug;8(7):2243-2253. PubMed PMID: 32173511
• Fielding SS, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner SS. Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma?. Eur Respir J. 2020 May;55(5). PubMed PMID: 32165403
• Messinger AI, Bui N, Wagner BD, Szefler SJ, Vu T, Deterding RR. Novel pediatric-automated respiratory score using physiologic data and machine learning in asthma. Pediatr Pulmonol. 2019 Aug;54(8):1149-1155. PubMed PMID: 31006993
• Fitzpatrick AM, Bacharier LB, Jackson DJ, Szefler SJ, Beigelman A, Cabana M, Covar R, Guilbert T, Holguin F, Lemanske RF, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Raissy HH, Zeiger RS, Mauger DT. Heterogeneity of Mild to Moderate Persistent Asthma in Children: Confirmation by Latent Class Analysis and Association with 1-Year Outcomes. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2617-2627.e4. PubMed PMID: 32156610
• Szefler SJ, Fitzgerald DA, Adachi Y, Doull IJ, Fischer GB, Fletcher M, Hong J, García-Marcos L, Pedersen S, Østrem A, Sly PD, Williams S, Winders T, Zar HJ, Bush A, Lenney W. A worldwide charter for all children with asthma. Pediatr Pulmonol. 2020 May;55(5):1282-1292. PubMed PMID: 32142219
• Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K, Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis. Eur Respir J. 2020 May;55(5). PubMed PMID: 32139458
• De Keyser HEH, Kaye L, Anderson WC, Gondalia R, Theye B, Szefler SJ, Stempel DA. Electronic medication monitors help determine adherence subgroups in asthma. Respir Med. 2020 Apr;164:105914. PubMed PMID: 32094102
• Ross KR, Szefler SJ. Introducing telehealth and adherence monitoring to school-centered asthma management. Pediatr Pulmonol. 2020 Mar;55(3):565-567. PubMed PMID: 31977164
• Fielding S, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. What is a clinically meaningful change in exhaled nitric oxide for children with asthma?. Pediatr Pulmonol. 2020 Mar;55(3):599-606. PubMed PMID: 31909561
• Abrams EM, Becker AB, Szefler SJ. Paradigm Shift in Asthma Therapy for Adolescents: Should It Apply to Younger Children as Well?. JAMA Pediatr. 2020 Mar 1;174(3):227-228. PubMed PMID: 31904766
• Szefler S, Vogelberg C, Jugovic B, de la Hoz A, Hamelmann E. Commentary: Treating Pediatric Asthma According Guidelines. Front Pediatr. 2019;7:109. PubMed PMID: 30972315
• Menzies-Gow A, Bafadhel M, Busse WW, Casale TB, Kocks JWH, Pavord ID, Szefler SJ, Woodruff PG, de Giorgio-Miller A, Trudo F, Fageras M, Ambrose CS. An expert consensus framework for asthma remission as a treatment goal. J Allergy Clin Immunol. 2020 Mar;145(3):757-765. PubMed PMID: 31866436
• Hamelmann E, von Mutius E, Bush A, Szefler SJ. Addressing the risk domain in the long-term management of pediatric asthma. Pediatr Allergy Immunol. 2020 Apr;31(3):233-242. PubMed PMID: 31732983
• Abrams EM, Szefler SJ, Becker AB. Time for Allergists to Consider the Role of Mouse Allergy in Non-Inner City Children with Asthma. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1778-1782. PubMed PMID: 30962154
• Szefler SJ, Vogelberg C, Bernstein JA, Goldstein S, Mansfield L, Zaremba-Pechmann L, Engel M, Hamelmann E. Tiotropium Is Efficacious in 6- to 17-Year-Olds with Asthma, Independent of T2 Phenotype. J Allergy Clin Immunol Pract. 2019 Sep - Oct;7(7):2286-2295.e4. PubMed PMID: 30922990
• Lenney W, Adachi Y, Bush A, Fischer GB, Hong J, Ostrem A, Pedersen S, Sly PD, Szefler SJ, Tilak R, Zar HJ. Asthma: moving toward a global children's charter. Lancet Respir Med. 2019 Apr;7(4):299-300. PubMed PMID: 30803924
• Anderson WC 3rd, Gondalia R, Hoch HE, Kaye L, Szefler SJ, Stempel DA. Screening for inhalation technique errors with electronic medication monitors. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):2065-2067. PubMed PMID: 30776523
• Anderson WC 3rd, Szefler SJ. Cost-effectiveness and comparative effectiveness of biologic therapy for asthma: To biologic or not to biologic?. Ann Allergy Asthma Immunol. 2019 Apr;122(4):367-372. PubMed PMID: 30703438
• Hoch H, Kattan M, Szefler SJ. Challenges in managing difficult-to-treat asthma in children: Stop, look, and listen. Pediatr Pulmonol. 2020 Mar;55(3):791-794. PubMed PMID: 31710161
• Bennett TD, Callahan TJ, Feinstein JA, Ghosh D, Lakhani SA, Spaeder MC, Szefler SJ, Kahn MG. Data Science for Child Health. J Pediatr. 2019 May;208:12-22. PubMed PMID: 30686480
• Tyler A, Cotter JM, Moss A, Topoz I, Dempsey A, Reese J, Szefler S, Hoch H. Outcomes for Pediatric Asthmatic Inpatients After Implementation of an Emergency Department Dexamethasone Treatment Protocol. Hosp Pediatr. 2019 Feb;9(2):92-99. PubMed PMID: 30670462
• Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin JT, Peters SP, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Teague WG, Thyne S, Martinez FD. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019 May;143(5):1934-1937.e4. PubMed PMID: 30660645
• Stempel H, Federico MJ, Szefler SJ. Applying a biopsychosocial model to inner city asthma: Recent approaches to address pediatric asthma health disparities. Paediatr Respir Rev. 2019 Nov;32:10-15. PubMed PMID: 31678039
• Lanz MJ, Gilbert I, Szefler SJ, Murphy KR. Can early intervention in pediatric asthma improve long-term outcomes? A question that needs an answer. Pediatr Pulmonol. 2019 Mar;54(3):348-357. PubMed PMID: 30609252
• Anderson WC 3rd, Gondalia R, Hoch HE, Kaye L, Barrett M, Szefler SJ, Stempel DA. Assessing asthma control: comparison of electronic-recorded short-acting beta-agonist rescue use and self-reported use utilizing the asthma control test. J Asthma. 2019 Nov 9;:1-5. [Epub ahead of print] PubMed PMID: 31668103
• Merchant R, Szefler SJ, Bender BG, Tuffli M, Barrett MA, Gondalia R, Kaye L, Van Sickle D, Stempel DA. Impact of a digital health intervention on asthma resource utilization. World Allergy Organ J. 2018;11(1):28. PubMed PMID: 30524644
• Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NN. Development and initial validation of the Asthma Severity Scoring System (ASSESS). J Allergy Clin Immunol. 2020 Jan;145(1):127-139. PubMed PMID: 31604088
• Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF Jr, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E. Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma. N Engl J Med. 2019 Sep 26;381(13):1227-1239. PubMed PMID: 31553835
• Szefler SJ. Legends of allergy and immunology: Donald Y. M. Leung. Allergy. 2020 Mar;75(3):724-726. PubMed PMID: 31465550
• Barnes PJ, Szefler SJ, Reddel HK, Chipps BE. Symptoms and perception of airway obstruction in asthmatic patients: Clinical implications for use of reliever medications. J Allergy Clin Immunol. 2019 Nov;144(5):1180-1186. PubMed PMID: 31330221
• Graham LM, Kerstjens HAM, Vogelberg C, Hamelmann E, Szefler SJ, Pisternick-Ruf W, Engel M, El Azzi G, Unseld A, Foggs MB. Safety of tiotropium Respimat(®) in black or African-American patients with symptomatic asthma. Respir Med. 2019 Aug;155:58-60. PubMed PMID: 31302579
• Kercsmar CM, Sorkness CA, Calatroni A, Gergen PJ, Bloomberg GR, Gruchalla RS, Kattan M, Liu AH, O'Connor GT, Pongracic JA, Szefler SJ, Teach SJ, Wildfire JJ, Wood RA, Zoratti EM, Busse WW. A computerized decision support tool to implement asthma guidelines for children and adolescents. J Allergy Clin Immunol. 2019 May;143(5):1760-1768. PubMed PMID: 30529451
• Fielding S, Pijnenburg M, de Jongste JC, Pike KC, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. Response. Chest. 2019 Jun;155(6):1313-1314. PubMed PMID: 31174655
• Abrams EM, Becker AB, Szefler SJ. Where does worsening asthma end and an asthma exacerbation begin?. Ann Allergy Asthma Immunol. 2019 Oct;123(4):329-330. PubMed PMID: 30468932
• Guilbert TW, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Reply. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):2102-2103. PubMed PMID: 31122886
• Cotter JM, Tyler A, Reese J, Ziniel S, Federico MJ, Anderson Iii WC, Kupfer O, Szefler SJ, Kerby G, Hoch HE. Steroid variability in pediatric inpatient asthmatics: survey on provider preferences of dexamethasone versus prednisone. J Asthma. 2020 Sep;57(9):942-948. PubMed PMID: 31113252
• Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF Jr, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 May 23;380(21):2009-2019. PubMed PMID: 31112384
• Vogelberg C, Szefler SJ, Vrijlandt EJLE, Boner AL, Engel M, El Azzi G, Vulcu SD, Moroni-Zentgraf PM, Eickmeier O, Hamelmann EH. Tiotropium add-on therapy is safe and reduces seasonal worsening in paediatric asthma patients. Eur Respir J. 2019 Jun;53(6). PubMed PMID: 31097514
• Szefler SJ, Raphiou I, Zeiger RS, Stempel D, Kral K, Pascoe S. Seasonal variation in asthma exacerbations in the AUSTRI and VESTRI studies. ERJ Open Res. 2019 Apr;5(2). PubMed PMID: 31086795
• Abrams EM, Becker AB, Szefler SJ. Where does worsening asthma end and an asthma exacerbation begin?. Ann Allergy Asthma Immunol. 2019 Oct;123(4):329-330. PubMed PMID: 30468932
• Mosnaim G, Stempel H, Szefler SJ, Stempel DA. Asthma Control-Time to Rethink Definitions and Criteria. J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1522-1523. PubMed PMID: 31076062
• Abrams EM, Szefler SJ, Becker AB. What Is the Role of Increasing Inhaled Corticosteroid Therapy in Worsening Asthma in Children?. J Allergy Clin Immunol Pract. 2019 Mar;7(3):842-847. PubMed PMID: 30446480
• Hamelmann E, Szefler SJ, Lau S. Severe asthma in children and adolescents. Allergy. 2019 Nov;74(11):2280-2282. PubMed PMID: 31074873
• Federico MJ, Szefler SJ. High-risk asthma: Never give up. Ann Allergy Asthma Immunol. 2019 May;122(5):441-442. PubMed PMID: 31054649
• Messinger AI, Bui N, Wagner BD, Szefler SJ, Vu T, Deterding RR. Novel pediatric-automated respiratory score using physiologic data and machine learning in asthma. Pediatr Pulmonol. 2019 Aug;54(8):1149-1155. PubMed PMID: 31006993
• Szefler S, Vogelberg C, Jugovic B, de la Hoz A, Hamelmann E. Commentary: Treating Pediatric Asthma According Guidelines. Front Pediatr. 2019;7:109. PubMed PMID: 30972315
• Fielding S, Pijnenburg M, de Jongste JC, Pike KC, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. Change in FEV(1) and Feno Measurements as Predictors of Future Asthma Outcomes in Children. Chest. 2019 Feb;155(2):331-341. PubMed PMID: 30359613
• Cicutto L, Gleason M, Haas-Howard C, White M, Hollenbach JP, Williams S, McGinn M, Villarreal M, Mitchell H, Cloutier MM, Vinick C, Langton C, Shocks DJ, Stempel DA, Szefler SJ. Building Bridges for Asthma Care Program: A School-Centered Program Connecting Schools, Families, and Community Health-Care Providers. J Sch Nurs. 2018 Oct 18;:1059840518805824. [Epub ahead of print] PubMed PMID: 30336726
• Abrams EM, Becker AB, Szefler SJ. Reply. J Pediatr. 2019 Jan;204:328-329. PubMed PMID: 30318367
• Abrams EM, Becker AB, Szefler SJ. Current State and Future of Biologic Therapies in the Treatment of Asthma in Children. Pediatr Allergy Immunol Pulmonol. 2018 Sep 1;31(3):119-131. PubMed PMID: 30283711
• Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. J Allergy Clin Immunol Pract. 2019 Mar;7(3):915-924.e7. PubMed PMID: 30267890
• Abrams EM, Becker AB, Szefler SJ. Use of Oral Corticosteroids in the Wheezy Toddler. J Pediatr. 2018 Oct;201:16-20. PubMed PMID: 30251636
• Abrams EM, Szefler SJ, Becker AB. Time for Allergists to Consider the Role of Mouse Allergy in Non-Inner City Children with Asthma. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1778-1782. PubMed PMID: 30962154
• Szefler SJ, Hoch HE, Tuffli M, Gondalia R, Barrett MA, Van Sickle D, Stempel DA. Quantifying beta-agonist utilization: Occasions or puffs?. J Allergy Clin Immunol Pract. 2019 Mar;7(3):1088-1090. PubMed PMID: 30218718
• Szefler SJ, Vogelberg C, Bernstein JA, Goldstein S, Mansfield L, Zaremba-Pechmann L, Engel M, Hamelmann E. Tiotropium Is Efficacious in 6- to 17-Year-Olds with Asthma, Independent of T2 Phenotype. J Allergy Clin Immunol Pract. 2019 Sep - Oct;7(7):2286-2295.e4. PubMed PMID: 30922990
• Lenney W, Adachi Y, Bush A, Fischer GB, Hong J, Ostrem A, Pedersen S, Sly PD, Szefler SJ, Tilak R, Zar HJ. Asthma: moving toward a global children's charter. Lancet Respir Med. 2019 Apr;7(4):299-300. PubMed PMID: 30803924
• Anderson WC 3rd, Gondalia R, Hoch HE, Kaye L, Szefler SJ, Stempel DA. Screening for inhalation technique errors with electronic medication monitors. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):2065-2067. PubMed PMID: 30776523
• Anderson WC 3rd, Szefler SJ. Cost-effectiveness and comparative effectiveness of biologic therapy for asthma: To biologic or not to biologic?. Ann Allergy Asthma Immunol. 2019 Apr;122(4):367-372. PubMed PMID: 30703438
• Bennett TD, Callahan TJ, Feinstein JA, Ghosh D, Lakhani SA, Spaeder MC, Szefler SJ, Kahn MG. Data Science for Child Health. J Pediatr. 2019 May;208:12-22. PubMed PMID: 30686480
• Tyler A, Cotter JM, Moss A, Topoz I, Dempsey A, Reese J, Szefler S, Hoch H. Outcomes for Pediatric Asthmatic Inpatients After Implementation of an Emergency Department Dexamethasone Treatment Protocol. Hosp Pediatr. 2019 Feb;9(2):92-99. PubMed PMID: 30670462
• Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin JT, Peters SP, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Teague WG, Thyne S, Martinez FD. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019 May;143(5):1934-1937.e4. PubMed PMID: 30660645
• Guilbert T, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Racial Disparities in Asthma-Related Health Outcomes in Children with Severe/Difficult-to-Treat Asthma. J Allergy Clin Immunol Pract. 2019 Feb;7(2):568-577. PubMed PMID: 30172020
• Lanz MJ, Gilbert I, Szefler SJ, Murphy KR. Can early intervention in pediatric asthma improve long-term outcomes? A question that needs an answer. Pediatr Pulmonol. 2019 Mar;54(3):348-357. PubMed PMID: 30609252
• Kercsmar CM, Sorkness CA, Calatroni A, Gergen PJ, Bloomberg GR, Gruchalla RS, Kattan M, Liu AH, O'Connor GT, Pongracic JA, Szefler SJ, Teach SJ, Wildfire JJ, Wood RA, Zoratti EM, Busse WW. A computerized decision support tool to implement asthma guidelines for children and adolescents. J Allergy Clin Immunol. 2019 May;143(5):1760-1768. PubMed PMID: 30529451
• Guilbert T, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Racial Disparities in Asthma-Related Health Outcomes in Children with Severe/Difficult-to-Treat Asthma. J Allergy Clin Immunol Pract. 2019 Feb;7(2):568-577. PubMed PMID: 30172020
• Abrams EM, Becker AB, Szefler SJ. Where does worsening asthma end and an asthma exacerbation begin?. Ann Allergy Asthma Immunol. 2019 Oct;123(4):329-330. PubMed PMID: 30468932
• Abrams EM, Szefler SJ, Becker AB. What Is the Role of Increasing Inhaled Corticosteroid Therapy in Worsening Asthma in Children?. J Allergy Clin Immunol Pract. 2019 Mar;7(3):842-847. PubMed PMID: 30446480
• Fielding S, Pijnenburg M, de Jongste JC, Pike KC, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. Change in FEV(1) and Feno Measurements as Predictors of Future Asthma Outcomes in Children. Chest. 2019 Feb;155(2):331-341. PubMed PMID: 30359613
• Hollenbach J, Villarreal M, Simoneau T, Langton C, Mitchell H, Flores G, M Cloutier M, Szefler S. Inaccuracy of asthma-related self-reported health-care utilization data compared to Medicaid claims. J Asthma. 2019 Sep;56(9):947-950. PubMed PMID: 30091938
• Cicutto L, Gleason M, Haas-Howard C, White M, Hollenbach JP, Williams S, McGinn M, Villarreal M, Mitchell H, Cloutier MM, Vinick C, Langton C, Shocks DJ, Stempel DA, Szefler SJ. Building Bridges for Asthma Care Program: A School-Centered Program Connecting Schools, Families, and Community Health-Care Providers. J Sch Nurs. 2020 Jun;36(3):168-180. PubMed PMID: 30336726
• Abrams EM, Becker AB, Szefler SJ. Reply. J Pediatr. 2019 Jan;204:328-329. PubMed PMID: 30318367
• Szefler SJ, Cloutier MM, Villarreal M, Hollenbach JP, Gleason M, Haas-Howard C, Vinick C, Calatroni A, Cicutto L, White M, Williams S, McGinn M, Langton C, Shocks D, Mitchell H, Stempel DA. Building Bridges for Asthma Care: Reducing school absence for inner-city children with health disparities. J Allergy Clin Immunol. 2019 Feb;143(2):746-754.e2. PubMed PMID: 30055181
• Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. J Allergy Clin Immunol Pract. 2019 Mar;7(3):915-924.e7. PubMed PMID: 30267890
• Szefler SJ, Hoch HE, Tuffli M, Gondalia R, Barrett MA, Van Sickle D, Stempel DA. Quantifying beta-agonist utilization: Occasions or puffs?. J Allergy Clin Immunol Pract. 2019 Mar;7(3):1088-1090. PubMed PMID: 30218718
• Guilbert T, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Racial Disparities in Asthma-Related Health Outcomes in Children with Severe/Difficult-to-Treat Asthma. J Allergy Clin Immunol Pract. 2019 Feb;7(2):568-577. PubMed PMID: 30172020
• Hollenbach J, Villarreal M, Simoneau T, Langton C, Mitchell H, Flores G, M Cloutier M, Szefler S. Inaccuracy of asthma-related self-reported health-care utilization data compared to Medicaid claims. J Asthma. 2019 Sep;56(9):947-950. PubMed PMID: 30091938
• Szefler SJ, Cloutier MM, Villarreal M, Hollenbach JP, Gleason M, Haas-Howard C, Vinick C, Calatroni A, Cicutto L, White M, Williams S, McGinn M, Langton C, Shocks D, Mitchell H, Stempel DA. Building Bridges for Asthma Care: Reducing school absence for inner-city children with health disparities. J Allergy Clin Immunol. 2019 Feb;143(2):746-754.e2. PubMed PMID: 30055181
• Szefler SJ. Boehringer-Ingelheim Satellite Symposium Choosing the Right Controller Therapy in Pediatric Patients with Asthma. Pediatr Pulmonol. 2018 Jun;53(S1):S171-S173. PubMed PMID: 29906344
• Hoch H, Kempe A, Brinton J, Szefler S. Feasibility of medication monitoring sensors in high risk asthmatic children. J Asthma. 2019 Mar;56(3):270-272. PubMed PMID: 29641374
• Szefler SJ. Boehringer-Ingelheim Satellite Symposium Choosing the Right Controller Therapy in Pediatric Patients with Asthma. Pediatr Pulmonol. 2018 Jun;53(S1):S171-S173. PubMed PMID: 29906344
• Messinger AI, Deterding RR, Szefler SJ. Bringing Technology to Day-to-Day Asthma Management. Am J Respir Crit Care Med. 2018 Aug 1;198(3):291-292. PubMed PMID: 29847147
• Messinger AI, Deterding RR, Szefler SJ. Bringing Technology to Day-to-Day Asthma Management. Am J Respir Crit Care Med. 2018 Aug 1;198(3):291-292. PubMed PMID: 29847147
• Szefler SJ, Jerschow E, Yoo B, Janampally P, Pazwash H, Holweg CTJ, Hudes G. Response to Omalizumab in Black and White Patients with Allergic Asthma. J Allergy Clin Immunol Pract. 2021 Jul 22. [Epub ahead of print] PubMed PMID: 34303017
• Udoko M, De Keyser H, Szefler SJ. Should children with asthma simply be treated as little adults?. Ann Allergy Asthma Immunol. 2021 Jul 11. [Epub ahead of print] PubMed PMID: 34260900
• Szefler SJ. Dr Elliot F. Ellis: Initiating personalized asthma management in children. Ann Allergy Asthma Immunol. 2018 Jul;121(1):3-6. PubMed PMID: 29758291
• Abrams EM, Szefler S. Ongoing asthma management in children during the COVID-19 pandemic: to step down or not to step down?. Lancet Respir Med. 2021 Aug;9(8):820-822. PubMed PMID: 34252377
• Federico MJ, Denlinger LC, Corren J, Szefler SJ, Fuhlbrigge AL. Exacerbation-Prone Asthma: A Biological Phenotype or a Social Construct. J Allergy Clin Immunol Pract. 2021 Jul;9(7):2627-2634. PubMed PMID: 34051392
• Izadi N, Baraghoshi D, Curran-Everett D, Zeiger RS, Szefler SJ, Covar RA. Factors Associated with Persistence of Severe Asthma from Late Adolescence to Early Adulthood. Am J Respir Crit Care Med. 2021 May 24. [Epub ahead of print] PubMed PMID: 34029510
• Chipps BE, Bacharier LB, Farrar JR, Jackson DJ, Murphy KR, Phipatanakul W, Szefler SJ, Teague WG, Zeiger RS. The pediatric asthma yardstick: Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Ann Allergy Asthma Immunol. 2018 Jun;120(6):559-579.e11. PubMed PMID: 29653238
• Martin J, Pijnenburg MW, Roberts G, Pike KC, Petsky H, Chang AB, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner S. Does lung function change in the months after an asthma exacerbation in children?. Pediatr Allergy Immunol. 2021 Aug;32(6):1208-1216. PubMed PMID: 33721352
• Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment. J Allergy Clin Immunol. 2021 May;147(5):1594-1601. PubMed PMID: 33667479
• Mosnaim G, Safioti G, Brown R, DePietro M, Szefler SJ, Lang DM, Portnoy JM, Bukstein DA, Bacharier LB, Merchant RK. Digital Health Technology in Asthma: A Comprehensive Scoping Review. J Allergy Clin Immunol Pract. 2021 Jun;9(6):2377-2398. PubMed PMID: 33652136
• Hoch H, Kempe A, Brinton J, Szefler S. Feasibility of medication monitoring sensors in high risk asthmatic children. J Asthma. 2019 Mar;56(3):270-272. PubMed PMID: 29641374
• Szefler SJ. Asthma across the lifespan: Time for a paradigm shift. J Allergy Clin Immunol. 2018 Sep;142(3):773-780. PubMed PMID: 29627424
• Sheehan WJ, Paul IM, Mauger DT, Moy JN, Szefler SJ, Jackson DJ, Fitzpatrick AM, Cabana MD, Covar R, Robison RG, Phipatanakul W. Adherence rates during a randomized controlled trial evaluating the use of blinded acetaminophen and ibuprofen in children with asthma. Contemp Clin Trials. 2021 May;104:106334. PubMed PMID: 33652129
• De Keyser HH, Szefler S. Asthma attacks in children are always preceded by poor asthma control: myth or maxim?. Breathe (Sheff). 2020 Sep;16(3):200169. PubMed PMID: 33447278
• Busse WW, Szefler SJ, Haselkorn T, Iqbal A, Ortiz B, Lanier BQ, Chipps BE. Possible Protective Effect of Omalizumab on Lung Function Decline in Patients Experiencing Asthma Exacerbations. J Allergy Clin Immunol Pract. 2021 Mar;9(3):1201-1211. PubMed PMID: 33223095
• Mosnaim GS, Stempel DA, Gonzalez C, Adams B, BenIsrael-Olive N, Gondalia R, Kaye L, Shalowitz M, Szefler S. The Impact of Patient Self-Monitoring Via Electronic Medication Monitor and Mobile App Plus Remote Clinician Feedback on Adherence to Inhaled Corticosteroids: A Randomized Controlled Trial. J Allergy Clin Immunol Pract. 2021 Apr;9(4):1586-1594. PubMed PMID: 33212239
• Szefler SJ, Chipps B. Challenges in the treatment of asthma in children and adolescents. Ann Allergy Asthma Immunol. 2018 Apr;120(4):382-388. PubMed PMID: 29625664
• Anderson WC 3rd, Gondalia R, De Keyser HE, Kaye L, Szefler SJ, Stempel DA. Digital assessment of medication utilization by age and diagnosis of asthma or COPD. J Allergy Clin Immunol Pract. 2021 Apr;9(4):1723-1725. PubMed PMID: 33212238
• Menzies-Gow A, Szefler SJ, Busse WW. The Relationship of Asthma Biologics to Remission for Asthma. J Allergy Clin Immunol Pract. 2021 Mar;9(3):1090-1098. PubMed PMID: 33130146
• Lee LA, Pedersen S, Pascoe SJ, Szefler SJ, Lenney W. No dose effect observed with chronic fluticasone propionate on growth velocity in children. Pediatr Allergy Immunol. 2021 Feb;32(2):377-381. PubMed PMID: 32966707
• Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, Billheimer D, Bleecker ER, Cardet JC, Castro M, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Holguin F, Jain S, Kenyon NJ, Krishnan JA, Kraft M, Kumar R, Liu MC, Ly NP, Moy JN, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Wechsler ME, Wenzel SE, White SR. The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations. J Biopharm Stat. 2020 Nov 1;30(6):1026-1037. PubMed PMID: 32941098
• Morris CR, Mauger DT, Suh JH, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Szefler SJ, Jackson DJ, Fitzpatrick AM. Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?. J Allergy Clin Immunol. 2018 Jul;142(1):308-311.e9. PubMed PMID: 29518418
• Anderson WC 3rd, Szefler SJ. Controlling the Risk Domain in Pediatric Asthma through Personalized Care. Semin Respir Crit Care Med. 2018 Feb;39(1):36-44. PubMed PMID: 29427984
• Kaplan A, Szefler SJ, Halpin DMG. Impact of comorbid conditions on asthmatic adults and children. NPJ Prim Care Respir Med. 2020 Aug 20;30(1):36. PubMed PMID: 32820164
• Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Harada N, Atsuta R, Fujisawa T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez FD, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in asthma: practical considerations. Eur Respir J. 2020 Aug;56(2). PubMed PMID: 32820024
• Navanandan N, Hamlington KL, Mistry RD, Szefler SJ, Liu AH. Oscillometry for acute asthma in the pediatric emergency department: A feasibility study. Ann Allergy Asthma Immunol. 2020 Nov;125(5):607-609. PubMed PMID: 32652127
• Abrams EM, Szefler SJ. COVID-19 and the impact of social determinants of health. Lancet Respir Med. 2020 Jul;8(7):659-661. PubMed PMID: 32437646
• Szefler SJ, Goldstein S, Vogelberg C, Bensch GW, Given J, Jugovic B, Engel M, Moroni-Zentgraf PM, Sigmund R, Hamelmann EH. Forced Expiratory Flow (FEF(25-75%)) as a Clinical Endpoint in Children and Adolescents with Symptomatic Asthma Receiving Tiotropium: A Post Hoc Analysis. Pulm Ther. 2020 Dec;6(2):151-158. PubMed PMID: 32399899
• Abrams EM, Szefler SJ. Managing Asthma during Coronavirus Disease-2019: An Example for Other Chronic Conditions in Children and Adolescents. J Pediatr. 2020 Jul;222:221-226. PubMed PMID: 32330469
• Hamelmann E, Szefler SJ. Efficacy and Safety of Tiotropium in Children and Adolescents. Drugs. 2018 Mar;78(3):327-338. PubMed PMID: 29368127
• Szefler SJ, Casale TB, Haselkorn T, Yoo B, Ortiz B, Kattan M, Busse WW. Treatment Benefit with Omalizumab in Children by Indicators of Asthma Severity. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2673-2680.e3. PubMed PMID: 32298853
• Federico MJ, McFarlane AE 2nd, Szefler SJ, Abrams EM. The Impact of Social Determinants of Health on Children with Asthma. J Allergy Clin Immunol Pract. 2020 Jun;8(6):1808-1814. PubMed PMID: 32294541
• Vrijlandt EJLE, El Azzi G, Vandewalker M, Rupp N, Harper T, Graham L, Szefler SJ, Moroni-Zentgraf P, Sharma A, Vulcu SD, Sigmund R, Chawes B, Engel M, Bisgaard H. Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2018 Feb;6(2):127-137. PubMed PMID: 29361462
• Lang JE, Fitzpatrick AM, Mauger DT, Guilbert TW, Jackson DJ, Lemanske RF Jr, Martinez FD, Strunk RC, Zeiger RS, Phipatanakul W, Bacharier LB, Pongracic JA, Holguin F, Cabana MD, Covar RA, Raissy HH, Tang M, Szefler SJ. Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids. J Allergy Clin Immunol. 2018 Apr;141(4):1459-1467.e2. PubMed PMID: 29273557
• Halpin DMG, Hamelmann EH, Frith PA, Moroni-Zentgraf PM, van Hecke B, Unseld A, Kerstjens HAM, Szefler SJ. Comparative Responses in Lung Function Measurements with Tiotropium in Adolescents and Adults, and Across Asthma Severities: A Post Hoc Analysis. Pulm Ther. 2020 Jun;6(1):131-140. PubMed PMID: 32180164
• Haselkorn T, Szefler SJ, Chipps BE, Bleecker ER, Harkins MS, Paknis B, Kianifard F, Ortiz B, Zeiger RS. Disease Burden and Long-Term Risk of Persistent Very Poorly Controlled Asthma: TENOR II. J Allergy Clin Immunol Pract. 2020 Jul - Aug;8(7):2243-2253. PubMed PMID: 32173511
• Fielding SS, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner SS. Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma?. Eur Respir J. 2020 May;55(5). PubMed PMID: 32165403
• Fitzpatrick AM, Bacharier LB, Jackson DJ, Szefler SJ, Beigelman A, Cabana M, Covar R, Guilbert T, Holguin F, Lemanske RF, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Raissy HH, Zeiger RS, Mauger DT. Heterogeneity of Mild to Moderate Persistent Asthma in Children: Confirmation by Latent Class Analysis and Association with 1-Year Outcomes. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2617-2627.e4. PubMed PMID: 32156610
• Szefler SJ, Fitzgerald DA, Adachi Y, Doull IJ, Fischer GB, Fletcher M, Hong J, García-Marcos L, Pedersen S, Østrem A, Sly PD, Williams S, Winders T, Zar HJ, Bush A, Lenney W. A worldwide charter for all children with asthma. Pediatr Pulmonol. 2020 May;55(5):1282-1292. PubMed PMID: 32142219
• Chipps BE, Haselkorn T, Paknis B, Ortiz B, Bleecker ER, Kianifard F, Foreman AJ, Szefler SJ, Zeiger RS. More than a decade follow-up in patients with severe or difficult-to-treat asthma: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) II. J Allergy Clin Immunol. 2018 May;141(5):1590-1597.e9. PubMed PMID: 28797732
• Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K, Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis. Eur Respir J. 2020 May;55(5). PubMed PMID: 32139458
• Chipps BE, Haselkorn T, Paknis B, Ortiz B, Bleecker ER, Kianifard F, Foreman AJ, Szefler SJ, Zeiger RS. More than a decade follow-up in patients with severe or difficult-to-treat asthma: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) II. J Allergy Clin Immunol. 2018 May;141(5):1590-1597.e9. PubMed PMID: 28797732
• De Keyser HEH, Kaye L, Anderson WC, Gondalia R, Theye B, Szefler SJ, Stempel DA. Electronic medication monitors help determine adherence subgroups in asthma. Respir Med. 2020 Apr;164:105914. PubMed PMID: 32094102
• Szefler SJ. Update on the NAEPPCC Asthma Guidelines: The wait is over, or is it?. J Allergy Clin Immunol. 2020 Dec;146(6):1275-1280. PubMed PMID: 32004522
• Ross KR, Szefler SJ. Introducing telehealth and adherence monitoring to school-centered asthma management. Pediatr Pulmonol. 2020 Mar;55(3):565-567. PubMed PMID: 31977164
• Fielding S, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. What is a clinically meaningful change in exhaled nitric oxide for children with asthma?. Pediatr Pulmonol. 2020 Mar;55(3):599-606. PubMed PMID: 31909561
• Abrams EM, Becker AB, Szefler SJ. Paradigm Shift in Asthma Therapy for Adolescents: Should It Apply to Younger Children as Well?. JAMA Pediatr. 2020 Mar 1;174(3):227-228. PubMed PMID: 31904766
• Menzies-Gow A, Bafadhel M, Busse WW, Casale TB, Kocks JWH, Pavord ID, Szefler SJ, Woodruff PG, de Giorgio-Miller A, Trudo F, Fageras M, Ambrose CS. An expert consensus framework for asthma remission as a treatment goal. J Allergy Clin Immunol. 2020 Mar;145(3):757-765. PubMed PMID: 31866436
• Hamelmann E, von Mutius E, Bush A, Szefler SJ. Addressing the risk domain in the long-term management of pediatric asthma. Pediatr Allergy Immunol. 2020 Apr;31(3):233-242. PubMed PMID: 31732983
• Hoch H, Kattan M, Szefler SJ. Challenges in managing difficult-to-treat asthma in children: Stop, look, and listen. Pediatr Pulmonol. 2020 Mar;55(3):791-794. PubMed PMID: 31710161
• Anderson WC 3rd, Gondalia R, Hoch HE, Kaye L, Barrett M, Szefler SJ, Stempel DA. Assessing asthma control: comparison of electronic-recorded short-acting beta-agonist rescue use and self-reported use utilizing the asthma control test. J Asthma. 2021 Feb;58(2):271-275. PubMed PMID: 31668103
• Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NN. Development and initial validation of the Asthma Severity Scoring System (ASSESS). J Allergy Clin Immunol. 2020 Jan;145(1):127-139. PubMed PMID: 31604088
• Szefler SJ. Legends of allergy and immunology: Donald Y. M. Leung. Allergy. 2020 Mar;75(3):724-726. PubMed PMID: 31465550
• Cotter JM, Tyler A, Reese J, Ziniel S, Federico MJ, Anderson Iii WC, Kupfer O, Szefler SJ, Kerby G, Hoch HE. Steroid variability in pediatric inpatient asthmatics: survey on provider preferences of dexamethasone versus prednisone. J Asthma. 2020 Sep;57(9):942-948. PubMed PMID: 31113252
• Cicutto L, Gleason M, Haas-Howard C, White M, Hollenbach JP, Williams S, McGinn M, Villarreal M, Mitchell H, Cloutier MM, Vinick C, Langton C, Shocks DJ, Stempel DA, Szefler SJ. Building Bridges for Asthma Care Program: A School-Centered Program Connecting Schools, Families, and Community Health-Care Providers. J Sch Nurs. 2020 Jun;36(3):168-180. PubMed PMID: 30336726
• Szefler SJ, Roberts G, Rubin AS, Zielen S, Kuna P, Alpan O, Anzures-Cabrera J, Chen Q, Holweg CTJ, Kaminski J, Putnam WS, Matthews JG, Kamath N. Efficacy, safety, and tolerability of lebrikizumab in adolescent patients with uncontrolled asthma (ACOUSTICS). Clin Transl Allergy. 2022 Jul;12(7):e12176. PubMed PMID: 35846226
• May KR, Oppenheimer JJ, Szefler SJ. Over-the-Counter Availability of Rescue Inhalers for Asthma. JAMA. 2022 Jul 12;328(2):215. PubMed PMID: 35819430
• Szefler SJ, Cicutto L, Brewer SE, Gleason M, McFarlane A, DeCamp LR, Brinton JT, Huebschmann AG. Applying dissemination and implementation research methods to translate a school-based asthma program. J Allergy Clin Immunol. 2022 Sep;150(3):535-548. PubMed PMID: 35569568
• Kho A, Daumit GL, Truesdale KP, Brown A, Kilbourne AM, Ladapo J, Wali S, Cicutto L, Matthews AK, Smith JD, Davis PD, Schoenthaler A, Ogedegbe G, Islam N, Mills KT, He J, Watson KS, Winn RA, Stevens J, Huebschmann AG, Szefler SJ. The National Heart Lung and Blood Institute Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Alliance. Health Serv Res. 2022 Jun;57 Suppl 1:20-31. PubMed PMID: 35383917
• Abdel-Aal A, Lisspers K, Williams S, Adab P, Adams R, Agarwal D, Barnard A, Bouloukaki I, van Boven JFM, Chavannes N, Dickens AP, van Gemert F, Escarrer M, Haroon S, Kayongo A, Kirenga B, Kocks JWH, Kotz D, Newby C, McNulty C, Metting E, Moral L, Papadakis S, Pinnock H, Price D, Ryan D, Singh SJ, Correia de Sousa J, Ställberg B, Szefler SJ, Taylor SJC, Tsiligianni I, Turner A, Weller D, Yusuf O, Tabyshova AK, Jordan RE. Prioritising primary care respiratory research needs: results from the 2020 International Primary Care Respiratory Group (IPCRG) global e-Delphi exercise. NPJ Prim Care Respir Med. 2022 Jan 28;32(1):6. PubMed PMID: 35091570
• Trivedi M, Pappalardo AA, Udoko M, Garg A, Phipatanakul W, Szefler SJ, Nyenhuis SM. Social Determinants of Health in Asthma Through the Life Course. J Allergy Clin Immunol Pract. 2022 Apr;10(4):953-961. PubMed PMID: 35033702
• Abrams EM, Jordan K, Szefler SJ. School Asthma Care During COVID-19: What We Have Learned and What We Are Learning. J Allergy Clin Immunol Pract. 2022 Feb;10(2):453-459. PubMed PMID: 34848382
• Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 Feb;149(2):488-516.e9. PubMed PMID: 34848210
• Bush A, Fitzpatrick AM, Saglani S, Anderson WC 3rd, Szefler SJ. Difficult-to-Treat Asthma Management in School-Age Children. J Allergy Clin Immunol Pract. 2022 Feb;10(2):359-375. PubMed PMID: 34838706
• Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF Jr, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME. Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma. Lancet Child Adolesc Health. 2021 Dec;5(12):862-872. PubMed PMID: 34762840
• Mosnaim GS, Stempel DA, Gonzalez C, Adams B, BenIsrael-Olive N, Gondalia R, Kaye L, Shalowitz M, Szefler S. Electronic medication monitoring versus self-reported use of inhaled corticosteroids and short-acting beta(2)-agonists in uncontrolled asthma. J Asthma. 2022 Oct;59(10):2024-2027. PubMed PMID: 34699302
• Keyser HH, Brinton JT, Bothwell S, Camacho M, Kempe A, Szefler SJ. Encouraging adherence in adolescents with asthma using financial incentives: An RCT. Pediatr Pulmonol. 2023 Oct;58(10):2823-2831. PubMed PMID: 37449768
• De Keyser H, Vuong V, Kaye L, Anderson WC 3rd, Szefler S, Stempel DA. Is Once Versus Twice Daily Dosing Better for Adherence in Asthma and Chronic Obstructive Pulmonary Disease?. J Allergy Clin Immunol Pract. 2023 Jul;11(7):2087-2093.e3. PubMed PMID: 37088377
• Papadopoulos NG, Szefler SJ, Bacharier LB, Maspero JF, Domingo C, Fiocchi A, Lee JK, Daizadeh N, Lederer DJ, Hardin M, Gall R, Djandji M, Siddiqui S, Jacob-Nara JA, Deniz Y, Rowe PJ. Assessment of dupilumab in children with moderate-to-severe type 2 asthma with or without evidence of allergic asthma. Allergy. 2023 Aug;78(8):2157-2167. PubMed PMID: 37059696
• Busse WW, Szefler SJ. Digital health in difficult-to-treat severe asthma. Lancet Respir Med. 2023 Jul;11(7):578-579. PubMed PMID: 36963416
• Szefler SJ, Jerschow E, Yoo B, Janampally P, Pazwash H, Holweg CTJ, Hudes G. Response to Omalizumab in Black and White Patients with Allergic Asthma. J Allergy Clin Immunol Pract. 2021 Nov;9(11):4021-4028. PubMed PMID: 34303017
• Udoko M, De Keyser H, Szefler SJ. Should children with asthma simply be treated as little adults?. Ann Allergy Asthma Immunol. 2021 Nov;127(5):520-521. PubMed PMID: 34260900
• Abrams EM, Szefler S. Ongoing asthma management in children during the COVID-19 pandemic: to step down or not to step down?. Lancet Respir Med. 2021 Aug;9(8):820-822. PubMed PMID: 34252377
• Federico MJ, Denlinger LC, Corren J, Szefler SJ, Fuhlbrigge AL. Exacerbation-Prone Asthma: A Biological Phenotype or a Social Construct. J Allergy Clin Immunol Pract. 2021 Jul;9(7):2627-2634. PubMed PMID: 34051392
• Anderson WC 3rd, Banzon TM, Chawes B, Papadopoulos NG, Phipatanakul W, Szefler SJ. Factors to Consider in Prescribing Asthma Biologic Therapies to Children. J Allergy Clin Immunol Pract. 2023 Mar;11(3):693-701. PubMed PMID: 36646381
• Carr TF, Fajt ML, Kraft M, Phipatanakul W, Szefler SJ, Zeki AA, Peden DB, White SR. Treating asthma in the time of COVID. J Allergy Clin Immunol. 2023 Apr;151(4):809-817. PubMed PMID: 36528110
• Izadi N, Baraghoshi D, Curran-Everett D, Zeiger RS, Szefler SJ, Covar RA. Factors Associated with Persistence of Severe Asthma from Late Adolescence to Early Adulthood. Am J Respir Crit Care Med. 2021 May 24. [Epub ahead of print] PubMed PMID: 34029510
• Stempel DA, Szefler SJ. Adding a Biologic to Asthma Therapy: The Role of Adherence in Selecting the Right Patient. J Allergy Clin Immunol Pract. 2022 Nov;10(11):2949-2950. PubMed PMID: 36357048
• Szefler SJ, Roberts G, Rubin AS, Zielen S, Kuna P, Alpan O, Anzures-Cabrera J, Chen Q, Holweg CTJ, Kaminski J, Putnam WS, Matthews JG, Kamath N. Efficacy, safety, and tolerability of lebrikizumab in adolescent patients with uncontrolled asthma (ACOUSTICS). Clin Transl Allergy. 2022 Jul;12(7):e12176. PubMed PMID: 35846226
• May KR, Oppenheimer JJ, Szefler SJ. Over-the-Counter Availability of Rescue Inhalers for Asthma. JAMA. 2022 Jul 12;328(2):215. PubMed PMID: 35819430
• Szefler SJ, Cicutto L, Brewer SE, Gleason M, McFarlane A, DeCamp LR, Brinton JT, Huebschmann AG. Applying dissemination and implementation research methods to translate a school-based asthma program. J Allergy Clin Immunol. 2022 Sep;150(3):535-548. PubMed PMID: 35569568
• Kho A, Daumit GL, Truesdale KP, Brown A, Kilbourne AM, Ladapo J, Wali S, Cicutto L, Matthews AK, Smith JD, Davis PD, Schoenthaler A, Ogedegbe G, Islam N, Mills KT, He J, Watson KS, Winn RA, Stevens J, Huebschmann AG, Szefler SJ. The National Heart Lung and Blood Institute Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Alliance. Health Serv Res. 2022 Jun;57 Suppl 1(Suppl 1):20-31. PubMed PMID: 35383917
• Abdel-Aal A, Lisspers K, Williams S, Adab P, Adams R, Agarwal D, Barnard A, Bouloukaki I, van Boven JFM, Chavannes N, Dickens AP, van Gemert F, Escarrer M, Haroon S, Kayongo A, Kirenga B, Kocks JWH, Kotz D, Newby C, McNulty C, Metting E, Moral L, Papadakis S, Pinnock H, Price D, Ryan D, Singh SJ, Correia de Sousa J, Ställberg B, Szefler SJ, Taylor SJC, Tsiligianni I, Turner A, Weller D, Yusuf O, Tabyshova AK, Jordan RE. Prioritising primary care respiratory research needs: results from the 2020 International Primary Care Respiratory Group (IPCRG) global e-Delphi exercise. NPJ Prim Care Respir Med. 2022 Jan 28;32(1):6. PubMed PMID: 35091570
• Martin J, Pijnenburg MW, Roberts G, Pike KC, Petsky H, Chang AB, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner S. Does lung function change in the months after an asthma exacerbation in children?. Pediatr Allergy Immunol. 2021 Aug;32(6):1208-1216. PubMed PMID: 33721352
• Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment. J Allergy Clin Immunol. 2021 May;147(5):1594-1601. PubMed PMID: 33667479
• Mosnaim G, Safioti G, Brown R, DePietro M, Szefler SJ, Lang DM, Portnoy JM, Bukstein DA, Bacharier LB, Merchant RK. Digital Health Technology in Asthma: A Comprehensive Scoping Review. J Allergy Clin Immunol Pract. 2021 Jun;9(6):2377-2398. PubMed PMID: 33652136
• Trivedi M, Pappalardo AA, Udoko M, Garg A, Phipatanakul W, Szefler SJ, Nyenhuis SM. Social Determinants of Health in Asthma Through the Life Course. J Allergy Clin Immunol Pract. 2022 Apr;10(4):953-961. PubMed PMID: 35033702
• Abrams EM, Jordan K, Szefler SJ. School Asthma Care During COVID-19: What We Have Learned and What We Are Learning. J Allergy Clin Immunol Pract. 2022 Feb;10(2):453-459. PubMed PMID: 34848382
• Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 Feb;149(2):488-516.e9. PubMed PMID: 34848210
• Bush A, Fitzpatrick AM, Saglani S, Anderson WC 3rd, Szefler SJ. Difficult-to-Treat Asthma Management in School-Age Children. J Allergy Clin Immunol Pract. 2022 Feb;10(2):359-375. PubMed PMID: 34838706
• Sheehan WJ, Paul IM, Mauger DT, Moy JN, Szefler SJ, Jackson DJ, Fitzpatrick AM, Cabana MD, Covar R, Robison RG, Phipatanakul W. Adherence rates during a randomized controlled trial evaluating the use of blinded acetaminophen and ibuprofen in children with asthma. Contemp Clin Trials. 2021 May;104:106334. PubMed PMID: 33652129
• Busse WW, Szefler SJ, Haselkorn T, Iqbal A, Ortiz B, Lanier BQ, Chipps BE. Possible Protective Effect of Omalizumab on Lung Function Decline in Patients Experiencing Asthma Exacerbations. J Allergy Clin Immunol Pract. 2021 Mar;9(3):1201-1211. PubMed PMID: 33223095
• Mosnaim GS, Stempel DA, Gonzalez C, Adams B, BenIsrael-Olive N, Gondalia R, Kaye L, Shalowitz M, Szefler S. The Impact of Patient Self-Monitoring Via Electronic Medication Monitor and Mobile App Plus Remote Clinician Feedback on Adherence to Inhaled Corticosteroids: A Randomized Controlled Trial. J Allergy Clin Immunol Pract. 2021 Apr;9(4):1586-1594. PubMed PMID: 33212239
• Anderson WC 3rd, Gondalia R, De Keyser HE, Kaye L, Szefler SJ, Stempel DA. Digital assessment of medication utilization by age and diagnosis of asthma or COPD. J Allergy Clin Immunol Pract. 2021 Apr;9(4):1723-1725. PubMed PMID: 33212238
• Mosnaim GS, Stempel DA, Gonzalez C, Adams B, BenIsrael-Olive N, Gondalia R, Kaye L, Shalowitz M, Szefler S. Electronic medication monitoring versus self-reported use of inhaled corticosteroids and short-acting beta(2)-agonists in uncontrolled asthma. J Asthma. 2022 Oct;59(10):2024-2027. PubMed PMID: 34699302
• Menzies-Gow A, Szefler SJ, Busse WW. The Relationship of Asthma Biologics to Remission for Asthma. J Allergy Clin Immunol Pract. 2021 Mar;9(3):1090-1098. PubMed PMID: 33130146
• Lee LA, Pedersen S, Pascoe SJ, Szefler SJ, Lenney W. No dose effect observed with chronic fluticasone propionate on growth velocity in children. Pediatr Allergy Immunol. 2021 Feb;32(2):377-381. PubMed PMID: 32966707
• Anderson WC 3rd, Gondalia R, Hoch HE, Kaye L, Barrett M, Szefler SJ, Stempel DA. Assessing asthma control: comparison of electronic-recorded short-acting beta-agonist rescue use and self-reported use utilizing the asthma control test. J Asthma. 2021 Feb;58(2):271-275. PubMed PMID: 31668103
• Filipow N, Turner S, Petsky HL, Chang AB, Frischer T, Szefler S, Vermeulen F, Stanojevic S. Variability in forced expiratory volume in 1 s in children with symptomatically well-controlled asthma. Thorax. 2024 Sep 27. [Epub ahead of print] PubMed PMID: 39332902
• Kakumanu S, Szefler S, Pappalardo AA, Sales AE, Baptist AP, Stern J, Nyenhuis SM. Applying the dissemination and implementation sciences to allergy and immunology: A Work Group Report from the AAAAI Quality, Adherence, and Outcomes Committee. J Allergy Clin Immunol. 2024 Aug 19. [Epub ahead of print] PubMed PMID: 39162669
• Huebschmann AG, Wagner NM, Gleason M, Brinton JT, Brtnikova M, Brewer SE, Begum A, Armstrong R, DeCamp LR, McFarlane A, DeKeyser H, Coleman H, Federico MJ, Szefler SJ, Cicutto LC. Reducing asthma attacks in disadvantaged school children with asthma: study protocol for a type 2 hybrid implementation-effectiveness trial (Better Asthma Control for Kids, BACK). Implement Sci. 2024 Aug 15;19(1):60. PubMed PMID: 39148094
• Papadopoulos NG, Bacharier LB, Jackson DJ, Deschildre A, Phipatanakul W, Szefler SJ, Gall R, Ledanois O, Jacob-Nara JA, Sacks H. Type 2 Inflammation and Asthma in Children: A Narrative Review. J Allergy Clin Immunol Pract. 2024 Sep;12(9):2310-2324. PubMed PMID: 38878861
• Szefler SJ. Stepping Up to Asthma Biologics: Checking All the Boxes. J Allergy Clin Immunol Pract. 2024 Jun;12(6):1547-1548. PubMed PMID: 38851252
• Brewer SE, DeCamp LR, Reedy J, Armstrong R, DeKeyser HH, Federico MJ, McFarlane A 2nd, Figlio G, Huebschmann AG, Szefler SJ, Cicutto L. Developing a Social Determinants of Health Needs Assessment for Colorado Kids (SNACK) Tool for a School-Based Asthma Program: Findings from a Pilot Study. Ethn Dis. 2023 Dec;DECIPHeR(Spec Issue):126-131. PubMed PMID: 38846737
• Brewer SE, Reedy J, Maestas D, DeCamp LR, Begum A, Brtnikova M, Cicutto L, Szefler SJ, Huebschmann A. Understanding Core Community Needs for School-Based Asthma Programming: A Qualitative Assessment in Colorado Communities. Ethn Dis. 2023 Dec;DECIPHeR(Spec Issue):35-43. PubMed PMID: 38846724
• Corren J, Szefler SJ, Sher E, Korenblat P, Soong W, Hanania NA, Berman G, Brusselle G, Zitnik R, Natalie CR, Sun L, Siu K, Wu WS, Lio P, Armstrong AW. Lebrikizumab in Uncontrolled Asthma: Reanalysis in a Well-Defined Type 2 Population. J Allergy Clin Immunol Pract. 2024 May;12(5):1215-1224.e3. PubMed PMID: 38360213
• Stempel DA, Szefler SJ. Is the assessment of asthma treatment efficacy sufficiently comprehensive?. J Allergy Clin Immunol. 2024 Mar;153(3):629-636. PubMed PMID: 38135011
• De Keyser H, Vuong V, Kaye L, Anderson WC 3rd, Szefler S, Stempel DA. Reply to "Breath-taking compliance: Does lower adherence translate to inferiority?". J Allergy Clin Immunol Pract. 2023 Dec;11(12):3813-3814. PubMed PMID: 38065642
• Kyler KE, Szefler SJ. Fifty Years of Unraveling the Clinical Pharmacology of Corticosteroids. J Pharm Sci. 2024 Jan;113(1):47-54. PubMed PMID: 37844761
• Keyser HH, Brinton JT, Bothwell S, Camacho M, Kempe A, Szefler SJ. Encouraging adherence in adolescents with asthma using financial incentives: An RCT. Pediatr Pulmonol. 2023 Oct;58(10):2823-2831. PubMed PMID: 37449768
• De Keyser H, Vuong V, Kaye L, Anderson WC 3rd, Szefler S, Stempel DA. Is Once Versus Twice Daily Dosing Better for Adherence in Asthma and Chronic Obstructive Pulmonary Disease?. J Allergy Clin Immunol Pract. 2023 Jul;11(7):2087-2093.e3. PubMed PMID: 37088377
• Papadopoulos NG, Szefler SJ, Bacharier LB, Maspero JF, Domingo C, Fiocchi A, Lee JK, Daizadeh N, Lederer DJ, Hardin M, Gall R, Djandji M, Siddiqui S, Jacob-Nara JA, Deniz Y, Rowe PJ. Assessment of dupilumab in children with moderate-to-severe type 2 asthma with or without evidence of allergic asthma. Allergy. 2023 Aug;78(8):2157-2167. PubMed PMID: 37059696
• Busse WW, Szefler SJ. Digital health in difficult-to-treat severe asthma. Lancet Respir Med. 2023 Jul;11(7):578-579. PubMed PMID: 36963416
• Anderson WC 3rd, Banzon TM, Chawes B, Papadopoulos NG, Phipatanakul W, Szefler SJ. Factors to Consider in Prescribing Asthma Biologic Therapies to Children. J Allergy Clin Immunol Pract. 2023 Mar;11(3):693-701. PubMed PMID: 36646381
• Carr TF, Fajt ML, Kraft M, Phipatanakul W, Szefler SJ, Zeki AA, Peden DB, White SR. Treating asthma in the time of COVID. J Allergy Clin Immunol. 2023 Apr;151(4):809-817. PubMed PMID: 36528110

Professional Memberships

• American Academy of Allergy Asthma and Immunology , Member
• American Academy of Pediatrics (AAP), Member
• Society of Pediatric Research , Member
• American Society of Pharmacology and Experimental Therapeutics , Member
• Colorado Allergy Society , Member
• American College of Allergy, Asthma and Immunology , Member
• American Thoracic Society (ATS), Member
• Colorado Trudeau Society/Medical Section of the American Lung Association of Colorado , Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• Children's Hospital Colorado

Specialty Information

Specialties

• Pediatrics, Board Certification
• Allergy and Immunology, Board Certification

Conditions & Treatments

• Lungs and Breathing - Asthma
• Immune System - Allergies
• Immune System
• Lungs and Breathing