Mark Abzug, MD
Professor, Pediatrics-Infectious Diseases

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Medical School:
  • MD, Boston University School of Medicine (1982)
Internship:
  • Strong Memorial Hospital of the University of Rochester Program (1983)
Residency:
  • Strong Memorial Hospital of the University of Rochester Program, Pediatrics (1985)
Fellowships:
  • University of Colorado (University Hospital) Program, Pediatric Infectious Diseases (1988)
Languages: English
Department: Pediatrics-Infectious Diseases

Professional Titles

  • Vice Chair for Academic Affairs

Research Interests

Dr. Abzug directs clinical research on patients with viral infections, infections in immunocompromised patients, and pediatric HIV infection. He is involved in national collaborative clinical trials of antiviral therapies, including studies of the National Institutes of Health Collaborative Antiviral Study Group and the National Institutes of Health International Maternal Pediatric Adolescent AIDS Clinical Trials Network.

Publications

  • Messacar K, Vogt M, Asturias E, Abzug MJ. Non-Polio Enteroviruses. In: Plotkin’s Vaccines, 8th Edition. Plotkin SA, Orenstein WA, Offit PA, Edwards KM (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2024.
  • Messacar K, Abzug MJ. Introduction to Picornaviridae. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2023.
  • Messacar K, Abzug MJ. Enterovirus and Parechoviruses. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2023.
  • Wattier RL, Bucayu RFT, Boge CLK, Ross RK, Yildirim I, Zaoutis TE, Palazzi DL, Vora SB, Castagnola E, Avilés-Robles M, Danziger-Isakov L, Tribble AC, Sharma TS, Arrieta AC, Maron G, Berman DM, Yin DE, Sung L, Green M, Roilides E, Belani K, Romero J, Soler-Palacin P, López-Medina E, Nolt D, Bin Hussain IZ, Muller WJ, Hauger SB, Halasa N, Dulek D, Pong A, Gonzalez BE, Abzug MJ, Carlesse F, Huppler AR, Rajan S, Aftandilian C, Ardura MI, Chakrabarti A, Hanisch B, Salvatore CM, Klingspor L, Knackstedt ED, Lutsar I, Santolaya ME, Shuster S, Johnson SK, Steinbach WJ, Fisher BT. Adjunctive Diagnostic Studies Completed Following Detection of Candidemia in Children: Secondary Analysis of Observed Practice From a Multicenter Cohort Study Conducted by the Pediatric Fungal Network. J Pediatric Infect Dis Soc. 2023 Sep 27;12(9):487-495. PubMed PMID: 37589394
  • Messacar K, Abzug MJ. Introduction to Picornaviridae. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2023.
  • Messacar K, Abzug MJ. Enterovirus and Parechoviruses. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2023.
  • Weinberg A, Giganti MJ, Sirois PA, Montepiedra G, Canniff J, Agwu A, Boivin MJ, Kapetanovic S, Abzug MJ. Coordination of inflammatory responses in children with perinatally acquired HIV infection. AIDS. 2022 Jul 1;36(8):1117-1127. PubMed PMID: 35442223
  • Jesson J, Crichton S, Quartagno M, Yotebieng M, Abrams EJ, Chokephaibulkit K, Le Coeur S, Aké-Assi MH, Patel K, Pinto J, Paul M, Vreeman R, Davies MA, Ben-Farhat J, Van Dyke R, Judd A, Mofenson L, Vicari M, Seage G 3rd, Bekker LG, Essajee S, Gibb D, Penazzato M, Collins IJ, Wools-Kaloustian K, Slogrove A, Powis K, Williams P, Matshaba M, Thahane L, Nyasulu P, Lukhele B, Mwita L, Kekitiinwa-Rukyalekere A, Wanless S, Goetghebuer T, Thorne C, Warszawski J, Galli L, van Rossum AMC, Giaquinto C, Marczynska M, Marques L, Prata F, Ene L, Okhonskaya L, Navarro M, Frick A, Naver L, Kahlert C, Volokha A, Chappell E, Pape JW, Rouzier V, Marcelin A, Succi R, Sohn AH, Kariminia A, Edmonds A, Lelo P, Lyamuya R, Ogalo EA, Odhiambo FA, Haas AD, Bolton C, Muhairwe J, Tweya H, Sylla M, D'Almeida M, Renner L, Abzug MJ, Oleske J, Purswani M, Teasdale C, Nuwagaba-Biribonwoha H, Goodall R, Leroy V. Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis. J Int AIDS Soc. 2022 Mar;25(3):e25871. PubMed PMID: 35255197
  • Wolf J, Abzug MJ, Anosike BI, Vora SB, Waghmare A, Sue PK, Olivero RM, Oliveira CR, James SH, Morton TH, Maron GM, Young JL, Orscheln RC, Schwenk HT, Bio LL, Willis ZI, Lloyd EC, Hersh AL, Huskins CW, Soma VL, Ratner AJ, Hayes M, Downes K, Chiotos K, Grapentine SP, Wattier RL, Lamb GS, Zachariah P, Nakamura MM. Updated Guidance on Use and Prioritization of Monoclonal Antibody Therapy for Treatment of COVID-19 in Adolescents. J Pediatric Infect Dis Soc. 2022 May 30;11(5):177-185. PubMed PMID: 35107571
  • Hay W. Levin MJ, Abzug MJ, Bunik M (Eds.). Current Diagnosis and Treatment-Pediatrics, 26th edition. McGraw-Hill, 2022.
  • Fisher BT, Zaoutis TE, Xiao R, Wattier RL, Castagnola E, Pana ZD, Fullenkamp A, Boge CLK, Ross RK, Yildirim I, Palazzi DL, Danziger-Isakov L, Vora SB, Arrieta A, Yin DE, Avilés-Robles M, Sharma T, Tribble AC, Maron G, Berman D, Green M, Sung L, Romero J, Hauger SB, Roilides E, Belani K, Nolt D, Soler-Palacin P, López-Medina E, Muller WJ, Halasa N, Dulek D, Hussain IZB, Pong A, Hoffman J, Rajan S, Gonzalez BE, Hanisch B, Aftandilian C, Carlesse F, Abzug MJ, Huppler AR, Salvatore CM, Ardura MI, Chakrabarti A, Santolaya ME, Localio AR, Steinbach WJ. Comparative Effectiveness of Echinocandins vs Triazoles or Amphotericin B Formulations as Initial Directed Therapy for Invasive Candidiasis in Children and Adolescents. J Pediatric Infect Dis Soc. 2021 Aug 10. [Epub ahead of print] PubMed PMID: 34374424
  • Haynes AS, Curtis DJ, Campbell K, Giller RH, Quinones RR, Verneris MR, Abzug MJ. An Immune Recovery-Based Revaccination Protocol for Pediatric Hematopoietic Stem Cell Transplant Recipients: Revaccination Outcomes Following Pediatric HSCT. Transplant Cell Ther. 2021 Apr;27(4):317-326. PubMed PMID: 33836875
  • Kapetanovic S, Giganti MJ, Abzug MJ, Lindsey JC, Sirois PA, Montepiedra G, Canniff J, Agwu A, Boivin MJ, Weinberg A. Plasma biomarker factors associated with neurodevelopmental outcomes in children with perinatal HIV infection and controlled viremia. AIDS. 2021 Jul 15;35(9):1375-1384. PubMed PMID: 33710019
  • Wolf J, Abzug MJ, Wattier RL, Sue PK, Vora SB, Zachariah P, Dulek DE, Waghmare A, Olivero R, Downes KJ, James SH, Pinninti SG, Yarbrough A, Aldrich ML, MacBrayne CE, Soma VL, Grapentine SP, Oliveira CR, Hayes M, Kimberlin DW, Jones SB, Bio LL, Morton TH, Hankins JS, Maron GM, Timberlake K, Young JL, Orscheln RC, Schwenk HT, Goldman DL, Groves HE, Huskins WC, Rajapakse NS, Lamb GS, Tribble AC, Lloyd EC, Hersh AL, Thorell EA, Ratner AJ, Chiotos K, Nakamura MM. Initial Guidance on Use of Monoclonal Antibody Therapy for Treatment of Coronavirus Disease 2019 in Children and Adolescents. J Pediatric Infect Dis Soc. 2021 May 28;10(5):629-634. PubMed PMID: 33388760
  • Chiotos K, Hayes M, Kimberlin DW, Jones SB, James SH, Pinninti SG, Yarbrough A, Abzug MJ, MacBrayne CE, Soma VL, Dulek DE, Vora SB, Waghmare A, Wolf J, Olivero R, Grapentine S, Wattier RL, Bio L, Cross SJ, Dillman NO, Downes KJ, Oliveira CR, Timberlake K, Young J, Orscheln RC, Tamma PD, Schwenk HT, Zachariah P, Aldrich ML, Goldman DL, Groves HE, Rajapakse NS, Lamb GS, Tribble AC, Hersh AL, Thorell EA, Denison MR, Ratner AJ, Newland JG, Nakamura MM. Multicenter Interim Guidance on Use of Antivirals for Children With Coronavirus Disease 2019/Severe Acute Respiratory Syndrome Coronavirus 2. J Pediatric Infect Dis Soc. 2021 Feb 13;10(1):34-48. PubMed PMID: 32918548
  • Abzug MJ. Enterovirus (nonpoliovirus)infections. In: Red Book: 2021 Report of the Committee on Infectious Diseases, 32nd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, 2021.
  • Abzug MJ. Human parechovirus infections. In: Red Book: 2021 Report of the Committee on Infectious Diseases, 32nd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, IL, 2021.
  • Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA; on behalf of the AFM working group. Acute flaccid myelitis: cause, diagnosis, and management. Lancet, 397:334-46, 2021.
  • Chiotos K, Hayes M, Kimberlin DW, Jones SB, James SH, Pinninti SG, Yarbrough A, Abzug MJ, MacBrayne CE, Soma VL, Dulek DE, Vora SB, Waghmare A, Wolf J, Olivero R, Grapentine S, Wattier RL, Bio L, Cross SJ, Dillman NO, Downes KJ, Oliveira CR, Timberlake K, Young J, Orscheln RC, Tamma PD, Schwenk HT, Zachariah P, Aldrich ML, Goldman DL, Groves HE, Rajapakse NS, Lamb GS, Tribble AC, Hersh AL, Thorell EA, Denison MR, Ratner AJ, Newland JG, Nakamura MM. Multicenter interim guidance on use of antivirals for children with COVID-19/SARS-CoV-2. J Pediatric Infect Dis Soc. 2020 Sep 12. [Epub ahead of print] PubMed PMID: 32918548
  • Chiotos K, Hayes M, Kimberlin DW, Jones SB, James SH, Pinninti SG, Yarbrough A, Abzug MJ, MacBrayne CE, Soma VL, Dulek DE, Vora SB, Waghmare A, Wolf J, Olivero R, Grapentine S, Wattier RL, Bio L, Cross SJ, Dillman NO, Downes KJ, Timberlake K, Young J, Orscheln RC, Tamma PD, Schwenk HT, Zachariah P, Aldrich M, Goldman DL, Groves HE, Lamb GS, Tribble AC, Hersh AL, Thorell EA, Denison MR, Ratner AJ, Newland JG, Nakamura MM. Multicenter initial guidance on use of antivirals for children with COVID-19/SARS-CoV-2. J Pediatric Infect Dis Soc. 2020 Apr 22. [Epub ahead of print] PubMed PMID: 32318706
  • Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, Messer R, Maloney J, Burakoff A, Barnes M, Rogers S, Lopez AS, Routh J, Gerber SI, Oberste MS, Nix WA, Abzug MJ, Tyler KL, Herlihy R, Dominguez SR. Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study. Lancet Infect Dis. 2020 Feb;20(2):230-239. PubMed PMID: 31859216
  • Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration. Outcomes of second-line antiretroviral therapy among children living with HIV: a global cohort analysis. J Int AIDS Soc. 23:e25477, 2020.
  • Hay W, Levin MJ, Bunik M, Abzug MJ (Eds.). Current Diagnosis and Treatment-Pediatrics, 25th edition. McGraw-Hill, 2020.
  • Messacar K, Abzug MJ. Enteroviruses (non-poliovirus). In: Nelson Textbook of Pediatrics, 21st edition. Kliegman RM, St. Geme III JW, Blum NJ, Shah S, Tasker RC, Wilson KM (Eds.). Elsevier Saunders Co., Philadelphia, Pennsylvania, 2020.
  • Messacar K, Abzug MJ, Dominguez SR. Acute Flaccid Myelitis Surveillance: A Signal Through the Noise. Pediatrics. 2019 Oct 7. [Epub ahead of print] PubMed PMID: 31591134
  • Messacar K, Abzug MJ, Dominguez SR. The changing epidemiology of acute flaccid paralysis warrants a paradigm shift in surveillance. J Med Virol. 2018 Jan;90(1):1-2. PubMed PMID: 29023852
  • Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis. Neurology. 2018 Nov 9. [Epub ahead of print] PubMed PMID: 30413631
  • Slogrove AL, Schomaker M, Davies MA, Williams P, Balkan S, Ben-Farhat J, Calles N, Chokephaibulkit K, Duff C, Eboua TF, Kekitiinwa-Rukyalekere A, Maxwell N, Pinto J, Seage G 3rd, Teasdale CA, Wanless S, Warszawski J, Wools-Kaloustian K, Yotebieng M, Timmerman V, Collins IJ, Goodall R, Smith C, Patel K, Paul M, Gibb D, Vreeman R, Abrams EJ, Hazra R, Van Dyke R, Bekker LG, Mofenson L, Vicari M, Essajee S, Penazzato M, Anabwani G, Q Mohapi E, N Kazembe P, Hlatshwayo M, Lumumba M, Goetghebuer T, Thorne C, Galli L, van Rossum A, Giaquinto C, Marczynska M, Marques L, Prata F, Ene L, Okhonskaia L, Rojo P, Fortuny C, Naver L, Rudin C, Le Coeur S, Volokha A, Rouzier V, Succi R, Sohn A, Kariminia A, Edmonds A, Lelo P, Ayaya S, Ongwen P, Jefferys LF, Phiri S, Mubiana-Mbewe M, Sawry S, Renner L, Sylla M, Abzug MJ, Levin M, Oleske J, Chernoff M, Traite S, Purswani M, Chadwick EG, Judd A, Leroy V. The epidemiology of adolescents living with perinatally acquired HIV: A cross-region global cohort analysis. PLoS Med. 2018 Mar;15(3):e1002514. PubMed PMID: 29494593
  • Messacar K, Asturias EJ, Hixon AM, Van Leer-Buter C, Niesters HGM, Tyler KL, Abzug MJ, Dominguez SR. Enterovirus D68 and acute flaccid myelitis-evaluating the evidence for causality. Lancet Infect Dis. 2018 Aug;18(8):e239-e247. PubMed PMID: 29482893
  • Strommen A, Hurst AL, Curtis D, Abzug MJ. Use of Intravenous Posaconazole in Hematopoietic Stem Cell Transplant Patients. J Pediatr Hematol Oncol. 2018 May;40(4):e203-e206. PubMed PMID: 29309375
  • Messacar K, Abzug MJ, Dominguez SR. The changing epidemiology of acute flaccid paralysis warrants a paradigm shift in surveillance. J Med Virol. 2018 Jan;90(1):1-2. PubMed PMID: 29023852
  • Bellavia A, Williams PL, DiMeglio LA, Hazra R, Abzug MJ, Patel K, Jacobson DL, Van Dyke RB, Geffner ME. Delay in sexual maturation in perinatally HIV-infected youths is mediated by poor growth. AIDS. 2017 Jun 1;31(9):1333-1341. PubMed PMID: 28358737
  • Neilan AM, Karalius B, Patel K, Van Dyke RB, Abzug MJ, Agwu AL, Williams PL, Purswani M, Kacanek D, Oleske JM, Burchett SK, Wiznia A, Chernoff M, Seage GR 3rd, Ciaranello AL. Association of Risk of Viremia, Immunosuppression, Serious Clinical Events, and Mortality With Increasing Age in Perinatally Human Immunodeficiency Virus-Infected Youth. JAMA Pediatr. 2017 May 1;171(5):450-460. PubMed PMID: 28346597
  • Melvin AJ, Montepiedra G, Aaron L, Meyer WA 3rd, Spiegel HM, Borkowsky W, Abzug MJ, Best BM, Crain MJ, Borum PR, Graham B, Anthony P, Shin K, Siberry GK. Safety and Efficacy of Atorvastatin in Human Immunodeficiency Virus-infected Children, Adolescents and Young Adults With Hyperlipidemia. Pediatr Infect Dis J. 2017 Jan;36(1):53-60. PubMed PMID: 27749649
  • Larochelle MB, Phan R, Craddock J, Abzug MJ, Curtis D, Robinson CC, Giller RH, Cosgrove S, Siringo F, McCourt E, Palestine AG. Cytomegalovirus Retinitis in Pediatric Stem Cell Transplants: Report of a Recent Cluster and the Development of a Screening Protocol. Am J Ophthalmol. 2017 Mar;175:8-15. PubMed PMID: 27746296
  • Melvin AJ, Montepiedra G, Aaron L, Meyer WA 3rd, Spiegel HM, Borkowsky W, Abzug MJ, Best BM, Crain MJ, Borum PR, Graham B, Anthony P, Shin K, Siberry GK. Safety and Efficacy of Atorvastatin in Human Immunodeficiency Virus-Infected Children, Adolescents and Young Adults with Hyperlipidemia. Pediatr Infect Dis J. 2016 Oct 3. [Epub ahead of print] PubMed PMID: 27749649
  • Larochelle MB, Phan R, Craddock J, Abzug MJ, Curtis D, Robinson CC, Giller RH, Cosgrove S, Siringo F, McCourt E, Palestine AG. Cytomegalovirus retinitis in pediatric stem cell transplants: report of a recent cluster and the development of a screening protocol. Am J Ophthalmol. 2016 Oct 13. [Epub ahead of print] PubMed PMID: 27746296
  • Camacho-Gonzalez AF, Chernoff MC, Williams PL, Chahroudi A, Oleske JM, Traite S, Chakraborty R, Purswani MU, Abzug MJ. Sexually Transmitted Infections in Youth With Controlled and Uncontrolled Human Immunodeficiency Virus Infection. J Pediatric Infect Dis Soc. 2016 Jul 20. [Epub ahead of print] PubMed PMID: 27440505
  • Messacar K, Abzug MJ, Dominguez SR. The Emergence of Enterovirus-D68. Microbiol Spectr. 2016 Jun;4(3). PubMed PMID: 27337448
  • Wolf ER, Beste S, Barr E, Wallace J, McFarland EJ, Abzug MJ, Darrow J, Melvin A. Health Outcomes of International HIV-infected Adoptees in the US. Pediatr Infect Dis J. 2016 Apr;35(4):422-7. PubMed PMID: 26629872
  • Messacar K, Abzug MJ, Dominguez SR. 2014 outbreak of enterovirus D68 in North America. J Med Virol. 2016 May;88(5):739-45. PubMed PMID: 26489019
  • Fisher BT, Ross RK, Roilides E, Palazzi DL, Abzug MJ, Hoffman JA, Berman DM, Prasad PA, Localio AR, Steinbach WJ, Vogiatzi L, Dutta A, Zaoutis TE. Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric Intensive Care Unit Patients at High Risk for Candidemia. J Pediatric Infect Dis Soc. 2016 Dec;5(4):458-461. PubMed PMID: 26407259
  • Abzug MJ, Michaels MG, Wald E, Jacobs RF, Romero JR, Sánchez PJ, Wilson G, Krogstad P, Storch GA, Lawrence R, Shelton M, Palmer A, Robinson J, Dennehy P, Sood SK, Cloud G, Jester P, Acosta EP, Whitley R, Kimberlin D. A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis. J Pediatric Infect Dis Soc. 2016 Mar;5(1):53-62. PubMed PMID: 26407253
  • Wolf ER, Beste S, Barr E, Wallace J, McFarland EJ, Abzug MJ, Darrow J, Melvin A. Health Outcomes of International HIV-Infected Adoptees in the U.S. Pediatr Infect Dis J. 2015 Nov 30. [Epub ahead of print] PubMed PMID: 26629872
  • Wattier RL, Dvorak CC, Hoffman JA, Brozovich AA, Bin-Hussain I, Groll AH, Castagnola E, Knapp KM, Zaoutis TE, Gustafsson B, Sung L, Berman D, Halasa NB, Abzug MJ, Velegraki A, Sharma TS, Fisher BT, Steinbach WJ. A Prospective, International Cohort Study of Invasive Mold Infections in Children. J Pediatric Infect Dis Soc. 2015 Dec;4(4):313-22. PubMed PMID: 26582870
  • Messacar K, Abzug MJ, Dominguez SR. 2014 outbreak of enterovirus D68 in North America. J Med Virol. 2015 Oct 21. [Epub ahead of print] PubMed PMID: 26489019
  • Olson D, Moen A, Barr E, Mirsky D, Schreiner T, Abzug MJ. An 8-Year-Old Boy With Ascending Paralysis. J Pediatric Infect Dis Soc. 2015 Dec;4(4):385-8. PubMed PMID: 26407267
  • Fisher BT, Ross RK, Roilides E, Palazzi DL, Abzug MJ, Hoffman JA, Berman DM, Prasad PA, Localio AR, Steinbach WJ, Vogiatzi L, Dutta A, Zaoutis TE. Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric Intensive Care Unit Patients at High Risk for Candidemia. J Pediatric Infect Dis Soc. 2015 Apr 29. [Epub ahead of print] PubMed PMID: 26407259
  • Abzug MJ, Michaels MG, Wald E, Jacobs RF, Romero JR, Sánchez PJ, Wilson G, Krogstad P, Storch GA, Lawrence R, Shelton M, Palmer A, Robinson J, Dennehy P, Sood SK, Cloud G, Jester P, Acosta EP, Whitley R, Kimberlin D. A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis. J Pediatric Infect Dis Soc. 2015 Apr 16. [Epub ahead of print] PubMed PMID: 26407253
  • Weinberg A, Muresan P, Richardson K, Fenton T, Dominguez T, Bloom A, Watts DH, Abzug MJ, Nachman SA, Levin MJ. Heterogeneity of T Cell Responses to Pandemic pH1N1 Monovalent Vaccine in HIV-Infected Pregnant Women. AIDS Res Hum Retroviruses. 2015 Nov;31(11):1170-7. PubMed PMID: 26322930
  • Mirani G, Williams PL, Chernoff M, Abzug MJ, Levin MJ, Seage GR 3rd, Oleske JM, Purswani MU, Hazra R, Traite S, Zimmer B, Van Dyke RB. Changing Trends in Complications and Mortality Rates Among US Youth and Young Adults With HIV Infection in the Era of Combination Antiretroviral Therapy. Clin Infect Dis. 2015 Dec 15;61(12):1850-61. PubMed PMID: 26270680
  • Weinberg A, Muresan P, Richardson KM, Fenton T, Dominguez T, Bloom A, Watts DH, Abzug MJ, Nachman SA, Levin MJ. Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine. PLoS One. 2015;10(4):e0122431. PubMed PMID: 25874544
  • Krogstad P, Patel K, Karalius B, Hazra R, Abzug MJ, Oleske J, Seage GR 3rd, Williams PL, Borkowsky W, Wiznia A, Pinto J, Van Dyke RB. Incomplete immune reconstitution despite virologic suppression in HIV-1 infected children and adolescents. AIDS. 2015 Mar 27;29(6):683-93. PubMed PMID: 25849832
  • Kimberlin DW, Jester PM, Sánchez PJ, Ahmed A, Arav-Boger R, Michaels MG, Ashouri N, Englund JA, Estrada B, Jacobs RF, Romero JR, Sood SK, Whitworth MS, Abzug MJ, Caserta MT, Fowler S, Lujan-Zilbermann J, Storch GA, DeBiasi RL, Han JY, Palmer A, Weiner LB, Bocchini JA, Dennehy PH, Finn A, Griffiths PD, Luck S, Gutierrez K, Halasa N, Homans J, Shane AL, Sharland M, Simonsen K, Vanchiere JA, Woods CR, Sabo DL, Aban I, Kuo H, James SH, Prichard MN, Griffin J, Giles D, Acosta EP, Whitley RJ. Valganciclovir for symptomatic congenital cytomegalovirus disease. N Engl J Med. 2015 Mar 5;372(10):933-43. PubMed PMID: 25738669
  • Rao S, Abzug MJ, Carosone-Link P, Peterson T, Child J, Siparksy G, Soranno D, Cadnapaphornchai MA, Simões EA. Intravenous acyclovir and renal dysfunction in children: a matched case control study. J Pediatr. 2015 Jun;166(6):1462-8.e1-4. PubMed PMID: 25708691
  • Messacar K, Schreiner TL, Maloney JA, Wallace A, Ludke J, Oberste MS, Nix WA, Robinson CC, Glodé MP, Abzug MJ, Dominguez SR. A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA. Lancet. 2015 Apr 25;385(9978):1662-71. PubMed PMID: 25638662
  • Abzug MJ. The enteroviruses: Problems in need of treatments. J Infect. 2014 Jan;68 Suppl 1:S108-14. PubMed PMID: 24119825
  • Halgrimson WR, Chan KH, Abzug MJ, Perkins JN, Carosone-Link P, Simões EA. Incidence of acute mastoiditis in Colorado children in the pneumococcal conjugate vaccine era. Pediatr Infect Dis J. 2014 May;33(5):453-7. PubMed PMID: 24732389
  • Abzug MJ. Acute sinusitis in children: do antibiotics have any role?. J Infect. 2014 Jan;68 Suppl 1:S33-7. PubMed PMID: 24119829
  • Abzug MJ. The enteroviruses: problems in need of treatments. J Infect. 2014 Jan;68 Suppl 1:S108-14. PubMed PMID: 24119825
  • Halgrimson WR, Chan KH, Abzug MJ, Perkins JN, Carosone-Link P, Simões EA. Incidence of Acute Mastoiditis in Colorado Children in the Pneumococcal Conjugate Vaccine Era. Pediatr Infect Dis J. 2013 Oct 22. [Epub ahead of print] PubMed PMID: 24153007
  • Williams PL, Abzug MJ, Jacobson DL, Wang J, Van Dyke RB, Hazra R, Patel K, Dimeglio LA, McFarland EJ, Silio M, Borkowsky W, Seage GR 3rd, Oleske JM, Geffner ME, International Maternal Pediatric and Adolescent AIDS Clinical Trials P219219C Study and the Pediatric HIVAIDS Cohort Study. Pubertal onset in children with perinatal HIV infection in the era of combination antiretroviral treatment. AIDS. 2013 Jul 31;27(12):1959-70. PubMed PMID: 24145244
  • Abzug MJ, Song LY, Levin MJ, Nachman SA, Borkowsky W, Pelton SI, International Maternal Pediatric Adolescent AIDS Clinical Trials Group P1024 and P1061s Protocol Teams. Antibody persistence and immunologic memory after sequential pneumococcal conjugate and polysaccharide vaccination in HIV-infected children on highly active antiretroviral therapy. Vaccine. 2013 Oct 1;31(42):4782-90. PubMed PMID: 23954381
  • Abzug MJ, Nachman SA, Muresan P, Handelsman E, Watts DH, Fenton T, Heckman B, Petzold E, Weinberg A, Levin MJ, International Maternal Pediatric Adolescent AIDS Clinical Trials Group P1086 Protocol Team. Safety and immunogenicity of 2009 pH1N1 vaccination in HIV-infected pregnant women. Clin Infect Dis. 2013 May;56(10):1488-97. PubMed PMID: 23378284
  • Kimberlin DW, Acosta EP, Prichard MN, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza. J Infect Dis. 2013 Mar 1;207(5):709-20. PubMed PMID: 23230059
  • Steinbach WJ, Roilides E, Berman D, Hoffman JA, Groll AH, Bin-Hussain I, Palazzi DL, Castagnola E, Halasa N, Velegraki A, Dvorak CC, Charkabarti A, Sung L, Danziger-Isakov L, Lachenauer C, Arrieta A, Knapp K, Abzug MJ, Ziebold C, Lehrnbecher T, Klingspor L, Warris A, Leckerman K, Martling T, Walsh TJ, Benjamin DK Jr, Zaoutis TE, International Pediatric Fungal Network. Results from a prospective, international, epidemiologic study of invasive candidiasis in children and neonates. Pediatr Infect Dis J. 2012 Dec;31(12):1252-7. PubMed PMID: 22982980
  • Abzug MJ, Qin M, Levin MJ, Fenton T, Beeler JA, Bellini WJ, Audet S, Sowers SB, Borkowsky W, Nachman SA, Pelton SI, Rosenblatt HM, International Maternal Pediatric Adolescent AIDS Clinical Trials Group P1024 and P1061s Protocol Teams. Immunogenicity, immunologic memory, and safety following measles revaccination in HIV-infected children receiving highly active antiretroviral therapy. J Infect Dis. 2012 Aug 15;206(4):512-22. PubMed PMID: 22693229
  • Lujan-Zilbermann J, Warshaw MG, Williams PL, Spector SA, Decker MD, Abzug MJ, Heckman B, Manzella A, Kabat B, Jean-Philippe P, Nachman S, Siberry GK, International Maternal Pediatric Adolescent AIDS Clinical Trials Group P1065 Protocol Team. Immunogenicity and safety of 1 vs 2 doses of quadrivalent meningococcal conjugate vaccine in youth infected with human immunodeficiency virus. J Pediatr. 2012 Oct;161(4):676-81.e2. PubMed PMID: 22622049
  • Feldman AG, Wachs M, Pomfret E, Abzug MJ, Pratscher L, Sundaram SS. Successful Non-directed Living Liver Donor Transplant for an Infant with Biliary Atresia During the COVID-19 Pandemic. Pediatric Transplantation, 2020, in press, doi.org/10.1111/petr.13816.
  • Haynes AS, Curtis DJ, Campbell K, Giller RH, Quinones RR, Verneris MR, Abzug MJ. An Immune Recovery-Based Revaccination Protocol for Pediatric Hematopoietic Stem Cell Transplant Recipients. Submitted, 2020.
  • Wolf J, Abzug MJ, Wattier RL, Sue PK, Vora SB, Zachariah P, Denison MR, Waghmare A, Olivero R, Downes KJ, James SH, Pinninti SG, Yarbrough A, Aldrich ML, MacBrayne CE, Soma VL, Grapentine S, Oliveira CR, Hayes M, Kimberlin DW, Jones SB, Dulek DE, Bio L, Morton TH, Hankins J, Mar?n-Alfaro GM, Timberlake K, Young J, Orscheln RC, Tamma PD, Schwenk HT, Goldman DL, Groves HE, Huskins CW, Rajapakse NS, Lamb GS, Tribble AC, Hersh AL, Thorell EA, Ratner AJ, Newland JG, Chiotos K, and Nakamura MM. Initial Guidance on Use of Monoclonal Antibody Therapy for Treatment of COVID-19 in Children and Adolescents. Submitted, 2020.
  • Abzug MJ. Enterovirus (nonpoliovirus)infections. In: Red Book: 2021 Report of the Committee on Infectious Diseases, 32nd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, in press.
  • Abzug MJ. Human parechovirus infections. In: Red Book: 2021 Report of the Committee on Infectious Diseases, 32nd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, IL, in press.
  • Chan KH, Abzug MJ, Liu AH. Sinusitis. In: Pediatric Allergy: Principles and Practice, 4th edition. Leung DYM, Sampson, Geha, Szefler (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2020, in press.
  • Messacar K, Abzug MJ. Introduction to Picornaviridae. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2020, in press.
  • Messacar K, Abzug MJ. Enterovirus and Parechoviruses. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2020, in press.
  • Messacar K, Asturias E, Chong PC, Klein M, Abzug MJ. Non-Polio Enteroviruses. In: Plotkin’s Vaccines, 8th Edition. Plotkin SA, Orenstein WA, Offit PA, Edwards KM (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2021, in press.
  • Kapetanovic S, Giganti MJ, Abzug MJ, Lindsey JC, Sirois PA, Montepiedra G, Canniff J, Agwu A, Boivin MJ, Weinberg A, for the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network. Plasma Biomarker Factors Associated with Neurodevelopmental Outcomes in Children with Perinatal HIV Infection and Controlled Viremia. Submitted, 2020.
  • Messacar K, Abzug MJ. Enteroviruses (non-poliovirus). In: Nelson Textbook of Pediatrics, 22nd edition. Kliegman RM, St. Geme III JW, Blum NJ, Shah S, Tasker RC, Wilson KM (Eds.). Elsevier Saunders Co., Philadelphia, Pennsylvania, in press.
  • Wolf J, Abzug MJ, Anosike BI, Vora SB, Waghmare A, Sue PK, Olivero RM, Oliveira CR, James SH, Morton TH, Maron GM, Young JL, Orscheln RC, Schwenk HT, Bio LL, Willis ZI, Lloyd EC, Hersh AL, Huskins CW, Soma VL, Ratner AJ, Hayes M, Downes K, Chiotos K, Grapentine SP, Wattier RL, Lamb GS, Zachariah P, Nakamura MM. Updated Guidance on Use and Prioritization of Monoclonal Antibody Therapy for Treatment of COVID-19 in Adolescents. J Pediatr Infect Dis Soc, 2021, in press.
  • Hay W. Levin MJ, Abzug MJ, Bunik M (Eds.). Current Diagnosis and Treatment-Pediatrics, 26th edition. McGraw-Hill, 2022, in press.
  • Abzug MJ, Messacar K. Human parechovirus infections. In: Red Book: 2024 Report of the Committee on Infectious Diseases, 32nd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, IL, in press.
  • Abzug MJ, Messacar K. Enterovirus (nonpoliovirus)infections. In: Red Book: 2024 Report of the Committee on Infectious Diseases, 32nd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, in press.
  • Messacar K, Abzug MJ. Introduction to Picornaviridae. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2021, in press.
  • Messacar K, Abzug MJ. Enterovirus and Parechoviruses. In: Principles and Practice of Pediatric Infectious Diseases, 6th Edition. Long SS, Prober CG, Fischer M (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2021, in press.
  • Messacar K, Vogt M, Asturias E, Abzug MJ. Non-Polio Enteroviruses. In: Plotkin’s Vaccines, 8th Edition. Plotkin SA, Orenstein WA, Offit PA, Edwards KM (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, 2021, in press.
  • Messacar K, Vogt M, Asturias E, Abzug MJ. Non-Polio Enteroviruses. In: Plotkin’s Vaccines, 8th Edition. Plotkin SA, Orenstein WA, Offit PA, Edwards KM (Eds.). Elsevier Ltd, Inc., Philadelphia, Pennsylvania, in press.
  • Messacar K, Abzug MJ. Enteroviruses (non-poliovirus). In: Nelson Textbook of Pediatrics, 22nd edition. Kliegman RM, St. Geme III JW, Blum NJ, Shah S, Tasker RC, Wilson KM (Eds.). Elsevier Saunders Co., Philadelphia, Pennsylvania, in press.
  • Abzug MJ, Messacar K. Enterovirus (nonpoliovirus)infections. In: Red Book: 2024 Report of the Committee on Infectious Diseases, 33rd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, in press.
  • Abzug MJ, Messacar K. Human parechovirus infections. In: Red Book: 2024 Report of the Committee on Infectious Diseases, 33rd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, IL, in press.
  • Guidance for prevention and management of COVID-19 in children and adolescents: A consensus statement from the Pediatric Infectious Diseases Society Pediatric COVID-19 Therapies Taskforce, submitted 2023.
  • Bunik M, Levin MJ, Abzug MJ, Schreiner T (Eds.). Current Diagnosis and Treatment-Pediatrics, 27th edition. McGraw-Hill, in press, 2024.
  • Messacar K, Abzug MJ. Enteroviruses (non-poliovirus). In: Nelson Textbook of Pediatrics, 22nd edition. Kliegman RM, St. Geme III JW, Blum NJ, Shah S, Tasker RC, Wilson KM (Eds.). Elsevier Saunders Co., Philadelphia, Pennsylvania, in press.
  • Abzug MJ, Messacar K. Enterovirus (nonpoliovirus) infections. In: Red Book: 2024 Report of the Committee on Infectious Diseases, 33rd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, in press.
  • Abzug MJ, Messacar K. Human parechovirus infections. In: Red Book: 2024 Report of the Committee on Infectious Diseases, 33rd edition. Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds). American Academy of Pediatrics, Elk Grove Village, IL, in press.
  • Todd JK, Glodé MP, Abzug MJ, Beam K (eds.). History of Pediatric Infectious Diseases and Epidemiology in Colorado from the Late 1800’s to 2023): Past is Prologue, in preparation, 2023.
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Professional Memberships

  • American Academy of Pediatrics (AAP), Member
  • Pediatric Infectious Disease Society, Member
  • Society For Pediatric Research (SPR), Member
  • American Board of Pediatrics Subboard of Pediatric Infectious Diseases Self-Assessment Team, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital

Specialty Information

Specialties
  • Pediatric Infectious Diseases, Board Certification (1994)
  • Pediatrics, Board Certification (1986)
Conditions & Treatments
  • Infections - Viral Infections
  • Immune System - AIDS
  • Immune System - AIDS / HIV Disease
  • Immune System - AIDS Immunization
  • Immune System
  • Infections
Clinical Interests
I am interested in Perinatal Infection, Enterovirus Infections and Infections in Immunocompromised Patients.

General Information

Medical Schools:
  • MD, Boston University School of Medicine (1982)
Internships:
  • Strong Memorial Hospital of the University of Rochester Program (1983)
Residency Programs:
  • Strong Memorial Hospital of the University of Rochester Program, Pediatrics (1985)
Fellowships:
  • University of Colorado (University Hospital) Program, Pediatric Infectious Diseases (1988)
Languages: English
Department: Pediatrics-Infectious Diseases
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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