Wei Wang, MD

Publications

• Wang W., Faubel S., Ljubanovic D., Mitra A., Kim J., Tao Y., Soloviev A., Reznikov L., Dinarello C. , Schrier R. and Edelstein C. Endotoxemic acute renal failure (ARF) is attenuated in caspase-1 deficient mice. Am J Physiol Renal Physiol, 288: F997, 2005
• Poole B., Wang W., Chen Y.C., Zolty E., Falk S., Mitra A., and Schrier R. The Role of Heme Oxygenase-1 in Endotoxemic Acute Renal Failure. Am J Physiol Renal Physiol 289(6): F1382-5, 2005
• Mitra M., Zolty E., Wang W. And Schrier R. Clinical Acute Renal Failure: Diagnosis and Management. Comprehensive Therapy. 31(4): 262-269, 2005
• Jani A., Wang W., Faubel S., Falk S., Ljubanovic D., Dursun, B., and Edelstein C. Ischemic acure renal failure (ARF) following nephrectomy impairs long-term renal function. Transplantation 81:800-3, 2006
• Schrier R., Zolty E. and Wang W. Sepsis and acute renal failure. In J.-L. Vincent (ed) “2006 Yearbook of Intensive Car and Emergency Medicine”. P673-679. Springer, 2006
• Wang W., Zolty E., Falk S., Basava V., Reznikov L. , and Schrier R. Pentoxifylline protects against endotoxin-induced acute renal failure in mice. Am J Physiol Renal Physiol 290: F1090-5, 2006
• Jani A., Wang W., Faubel S., Falk S., Ljubanovic D., Dursun, B., and Edelstein C. Ischemic acure renal failure (ARF) following nephrectomy impairs long-term renal function. Transplantation 81:800-3, 2006
• Wang W, Zolty E, Falk S, Summer S, Stearman R, Geraci M and Schrier R. Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice. Am J Physiol Renal Physiol 293: F1131-1136. 2007
• Chan L, Wiseman A, Wang W Jani A and Kam I: Outcomes and complications of renal transplantation. In Schrier RW (ed), Diseases of the Kidney and Urinary Tract, VIII Edition, Lippincott Williams and Wilkins, Baltimore, 2007
• Rivard C, Wang W and Chan L: Hypernatremic States. In Seldin, DW and Giebisch G (eds),The Kidney: Physiology and Pathophysiology IV Edition. Raven Press, New York, 2007
• Wang W, Zolty E, Falk S, Summer S, Zhou Z, Gengaro P, Faubel S, Alp N, Channon K and Schrier R. Endotoxemia-Related Acute Kidney Injury in Transgenic Mice with Endothelial Overexpression of GTP Cyclohydrolase-1 (GTPCH). Am J Physiol Renal Physiol 294 (3):F571-6, 2008
• Wang W, Li C, Summer S, Falk S, Wang W, Ljubanovic D and Schrier R. Role of AQP1 in endotoxemia-induced acute kidney injury. Am J Physiol Renal Physiol 294 (6): F1473-80, 2008
• Zhou Z, Gengaro P, Wang W, Wang XQ, Li C, Faubel S, Riverd C and Schrier R. Role of NF-{kappa}B and PI 3-kinase/Akt in TNF-{alpha}-induced cytotoxicity in microvascular endothelial cells. Am J Physiol Renal Physiol 295 (4): F932-41, 2008
• Schrier R, Bansal S and Wang W: Acute Kidney Failure in Sepsis. In Ronco C, Kellum J, Jorres A (eds)Management of Acute Kidney Problems
• Wang W, Bansal S, Falk S, Ljubanovic D and Schrier R. Ghrelin protects mice against endotoxemia-induced acute kidney injury. Am J Physiol Renal Physiol 297(4), F1032, 2009.
• Bansal S, Wang W, Falk S and Schrier R. Combination therapy with albumin and pentoxifylline protects against acute kidney injury during endotoxemic shock in mice. Ren Fail 31 (9) 848, 2009
• Reed-Gitomer BY, Bekheinia MR, Wang W, Masoumi A, Gianani R, Wong R, Schrier RW. Angiogenesis and autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 20:276A, 2009
• Reed-Gitomer BY, Wang W, Masoumi A, Cadnapaphornchai M, Schrier RW. Angiogenesis and autosomal dominant polycystic kdiney disease. Proc. Butcher Symposium on Genomics and Technology 88, 2009
• Reed B, masoumi A, Elassan E, Wang W, McFann K, Cadnapaphornchai M, Schrier RW. Angiogenic growth factors in young patients with autosomal dominant polycystic kidney disease. Kid Int. In review. 2010
• Wang W, Gitomer BY, McFann K, Yan X-D, Schrier RW. Type II diatebes in patients with autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2010; 21:889A
• Schrier RW, Wang W, Chonchol M, Cadnapaphomchai M, McFann K, Yan X-D, Gitomer B. Klotho expression is reduced in human kidneys from patients with autosomal dominant polycystic kidney disease. J Am So Nephol. 2010; 21:887A
• Gitomer BY, Cadnapaphomchai M, Wang W, Masoumi A, McFann K, Yan X-D, Schrier RW. Vascular endothelial growth factor level correlates with disease severity in young patients with autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2010; 21:526-527A
• Gitomer BY, Cadnapaphomchai M, Masoumi A, Chonchol M, McFann K, Wang W, Schrier RW. Vitamin D deficiency and reanl volume in autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2010; 529A
• Masoumi A Gitomer BY, Schrier RW, Wang W, Chapman AB, Perrone RD, Torres VE, Steinman TI, Miskulin DC. Effect of angiotensin converting enzyme (ACE) inhibition and angiotensin receptor blockade on urinary pH in ADPKD. J Am Soc Nephrol. 2010; 21:532A
• Cadnapaphomchai MA, Gitomer BY, Chonchol MB, McFann K, wang W, Schrier RW. Prevalence of vitamin D deficiency in children and young adults with autosomal dominant polycystic kidney disease. J Am Soc nephrol. 2010;21:882A
• Reed-Gitomer BY, Wang W, McFann K, Cadnaphornchai M, Schrier RW, Chonchol M.Vitamin D and severity of autosomal dominant polycystic kidney disease. In: Polycystic kidney disease from bench to bedside, Proceedings of the FASEB Summer research Conference 2011
• Sharma S, Chonchol MB, Gitomer BY, Wang W, Wolf MS, Cadnapaphornchai M, Schrier RW. Fibroblast growth factor 23 levels are elevated in children and adults with autosomal dominant polycystic kidney disease and preserved renal function. J Am Soc Nephrol 22: 297A
• Wang W, Schrier RW, Gitomer BY. MicroRNA regulation of angiogenesis in autosomal dominant polycystic kidney disease. J Am Soc Nephrol 22:577A
• Reed BY, Wang W. Angiogenesis and the pathogenesis of autosomal dominant polycystic kidney disease. In: Nephrology, Intech,Rijeka, Croatia 2012 In press
• Reed B, Helal I, McFann K, Wang W, Yan XD, Schrier RW. The impact of type II diabetes mellitus in autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. Dec 29, 2011 epub ahead of print
• The impact of type II diabetes mellitus in patients with autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 27: 2862-5, 2012
• Circulating Micro-RNAs in Acute Kidney Injury after Liver Transplantation: Early Observations. Berenice Gitomer, Charles Edelstein, Wei Wang, Eric Lader, Jonathan Shaffer, Michel Chonchol. 2012 Annual ASN conference, San Diego, CA, USA
• A Functional Variant of Angiopoietin-1 is Associated with Hypertension and Severity of Renal Structural Damage in Patients with ADPKD. Wei Wang, MD, Michel Chonchol, MD, Robert Schrier, MD, Kim McFann, and Berenice Gitomer, PhD. 2012 Annual ASN Conference. San Diego, CA, USA
• Aberrant VEGF and sFlt-1 Expression in ADPKD Patients. Wei Wang, MD, Michel Chonchol, MD, Robert Schrier, MD and Berenice Gitomer, PhD. 2012 Annual ASN Conference. San Diego, CA, USA
• Circulating Micro-RNAs in Acute Kidney Injury after Liver Transplantation: Early Observations. Berenice Gitomer, Charles Edelstein, Wei Wang, Eric Lader, Jonathan Shaffer, Michel Chonchol. 2012 Annual ASN Conference. San Diego, CA, USA
• Affected Parent Gender and Severity of ADPKD. Berenice Gitomer, Kim McFann, Xiang-Dong Yan, Wei Wang, Imed Helal, Godela Brosnahan, Robert Schrier. 2012 Anuual ASN Conference. San Diego, CA, USA
• Pravastatin and Angiogenesis in ADPKD. J Am Soc Nephrol. SA-PO273, 2013
• Thrombospondin and Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol SA-P0274, 2013
• Statin Effect on Human ADPKD Tubular Epithelial Cell Proliferation. Wei Wang, Melissa Cadnapaphornchai, Michel Chonchol, Robert Schrier and Berenice Gitomer. J Am Soc Nephrol. 2014, Philadelphia, PA. USA
• MitoQ Modulates Hypoxia-Inducible factor-1 in ADPKD. Wei Wang, Michel Chonchol, Kristen Jablonski, Robert Schrier, and Berenice Gitomer. J Am Soc Nephrol. 2014, Philadelphia, PA, USA
• Effect of Simvastatin on Cell Adhesion in ADPKD. Wang W, Cadnapaphornchai M, Chonchol M, Gitomer B. San Diego, 2015 American Society of Nephrology Annual Meeting
• Aberrant Expression of Rad9 in ADPKD Wang W, Chonchol M, Gitomer B. San Diego. 2015 American Society of Nephrology Annual Meeting
• Brody J, Wang, W, Schrier R and Gitomer B. Effects of smoking on ADPKD: Frequency of Vascular events and concentrations of Soluble CD40 Ligand. General Medicine. (2015) 3 (2), 175
• Klawitter J, McFann K, Pennington AT, Wang W, Klawitter J, Christians U, Schrier RW, Gitomer B, Cadnapaphornchai MA. Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2015 Sep 4;10(9):1534-41. PubMed PMID: 26224879
• Wang W, You ZY, Cadnapaphornchai M, Chonchol M and Gitomer B: Angiogenic Factors Predict Progression in Young Patients with Autosomal Dominant Polycystic Kidney Disease. EC Pediatrics. 2.4 (2016): 205-214
• Nowak K, Chonchol M, Ikizler T, Farmer-Bailey H, Salas N, Chaudhry R, Wang W, Smits G, Tengesdal I, Dinarello C and Hung A. IL-1 inhibition and vascular function in CKD. J Am Soc Nephrol, 2016,
• Wang W, Chonchol M and Gitomer B: Fibrosis Markers in Autosomal Dominant Polycystic Kidney Disease (ADPKD). American Society of Nephrology Annual Meeting. Chicago, Nov 2016
• Mineralocorticoid antagonism and vascular oxidative stress and inflammation in early autosomal dominant polycystic kidney disease: a randomized-controlled trial. Nowak KL, Wang W, Gitomer BY, Jovanovich A, Farmer-Balley H and Chonchol M. American Society of Nephrology Annual Meeting. New Orleans, LA, FR-PO200, Nov 2017
• Mineralocorticoid antagonism and vascular function in early autosomal dominant polycystic kidney disease: a randomized-controlled trial. Nowak KL, Gitomer BY, Farmer-Balley H Wang W, George D, Malaczewski MR and Chonchol M. American Society of Nephrology Annual Meeting. New Orleans, FR-PO304, 2017
• Nowak KL, Wang W, Farmer-Bailey H, Gitomer B, Malaczewski M, Klawitter J, Jovanovich A, Chonchol M. Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2018 Oct 08; 13(10):1493-1501 https://www.ncbi.nlm.nih.gov/pubmed/30228110
• Nowak KL, Gitomer B, Farmer-Bailey H, Wang W, MD1, Malaczewski M, Klawitter J, You ZY, George D, Patel N, Jovanovich A, Chonchol M. Mineralocorticoid Antagonism and Vascular Function in Early Autosomal Dominant Polycystic Kidney Disease: A Randomized-Controlled Trial. AJKD
• Marek Hanudel, Isidro Salusky, Renata Pereira, Wei Wang, Zhiying You, Berenice Gitomer, Kristen Nowak, Michel Chonchol. FGF23, Erythropoietin, and Erythroferrone Levels in Autosomal Dominant Polycystic Kidney Disease Patients. TH-PO190 October 25, 2018 | 10:00 AM - 12:00 PM / Exhibit Hall, San Diego Convention Center
• Berenice Gitomer, Ronald Perrone, Theodore Steinmart, Alan Yu, Kyongtae Bae, Kaleab Abebe, Michel Chonchol, Zhiying You, Wei Wang, Godela Brosnahan, Kristen Nowak.Katharina Hopp, Peter Harris, Vincente Torres, Arlene Chapman. Nephrolithiasis as a Risk Factor for Kidney Disease Progression in ADPKD. SA-PO506 October 27, 2018 | 10:00 AM - 12:00 PM / Exhibit Hall, San Diego Convention Center
• Circulating interleukin-6 level predicts decline in kidney function in autosomal dominant polycystic kidney disease. Gitomer BY, Wang W, Nowak KL, Hopp K, You ZY, Brosnahan G, Harris P, Torres VE, Chapman A, Perrone RD, Steinman TI, Yu AS, Abebe KZ, Bae KT, Chonchol M. American Society of Nephrololgy Annual meeting. New Orleans, LA, Nov. 2017
• Berenice Gitomer, Arlene Chapman, Ronald Perrone, Theodore Steinman, Alan Yu, Kyongtae Bae, Kaleab Abebe, Michel Chonchol, Wei Wang, Aik Tan, Zhiying You, Kristen Nowak, Katharina Hopp, Godela Brosnahan, Peter Harris, Vincente Torres. Serum Micro RNA Levels and Disease Progression in ADPKD. SA-PO507 October 27, 2018 | 10:00 AM - 12:00 PM / Exhibit Hall, San Diego Convention Center
• Lama Noureddine, Berenice Gitomer, Zhiying You, Wei Wang, Michel Chonchol, Diana Jalal. Exploring KIM-1 as a Marker for Kidney Disease in ADPKD: Analysis from the HALT-PKD Studies. SA-PO513 October 27, 2018 | 10:00 AM - 12:00 PM / Exhibit Hall, San Diego Convention Center
• d. Nowak KL, Gitomer B, Farmer-Bailey H, Wang W, Malaczewski M, Klawitter J, You Z, George D, Jovanovich A, Patel N, Chonchol M. Mineralocorticoid antagonism and vascular function in early autosomal dominant polycystic kidney disease: a randomized-controlled trial. Am J Kidney Dis, 74:213-223, 2019; PMCID: PMC6660387
• Wang W, Chonchol M, Seals D, Nowak KL. Dietary Sodium Restriction Lowers a urinary NGAL in Adults with Moderately Elevated Systolic Blood Pressure Free from Chronic Kidney Disease. J Investig Med. 2020, 68: 1271-1275
• Wang W, You Z, Gitomer B, Brosnahan G et al: Overweight and obesity are predictors of pain in the HALT-PKD studies. J Am Soc Neph
• Griffin, B.R., You, Z., Noureddine, L., Gitomer, B., Perrenoug, L., Wang, W., Chonchol, M., Jalal, D. Kim-1 and kidney disease progression in autosomal doniant polycystic kidney disease.: HALT PKD results. Am J Nephrol. 2020, 51(6) 473-479.
• Brosnahan, G.M., You, Z., Wang, W., Gitomer, B.Y., Chonchol, M. Serum uric acid and progression of autosomal dominant polycystic kidney disease: Results from the HALT-PKD trials. Curr Hypertens Rev. 2020 Aug 17 doi:10:2174/1573402116666200817113125. Online ahead of print.
• Nowak KL, Jovanovich A, Farmer-Bailey H, Bispham N, Struemph T, Malaczewski M, Wang W and Chonchol M. Vascular Dysfunction, Oxidative Stress, and inflammation in Chronic Kidney Disease. Kidney 360 25 June 2020, 1(6): 501-509.
• Nowak KL, Farmer-Bailey H, Cadnapaphornchai MA, You ZY, George D, Wang W, Jovanovich A, Soranno D, Gitomer B and Chonchol M. Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease: Design and Baseline Characteristics of Participants. Contemp Clin Trials Commun 2020 Aug 12; 19:100635.
• Brosnahan GM, You ZY, Wang W, Gitomer BY, Chonchol M. for the HALT PKD investigators. Serum Uric Acid and Progression of Autosomal Dominant Polycystic Kidney Disease: Results from the HALT PKD Trials. Curr Hypertens Rev
• Brosnahan GM, Wang W, Gitomer B. Struemph T, George D, You ZY, Nowak K, Klawitter J, Chonchol M. Metformin Therapy in Autosomal Dominant Polycystic Kidney Disease: A Feasibility Study. Am J Kidney Dis
• Nowak KL, Farmer-Bailey H, Wang W, You Z, Steele C, Cadnapaphornchai M, Klawitter J, Patel N, George D, Jovanovich A, Soranno DE, Gitomer B, Chonchol M. Curcumin therapy to treat vascular dysfunction in children and young adults with autosomal dominant polycystic kidney disease, Clin J Am Soc Nephrol
• . Hopp K, Catenacci V, Dwivedi N, Kline TL, Wang W, You Z, Nguyen DT, Bing K, Poudyal B, Johnson G, Jackman MR, Miller M, Steele C, MacLean P, Nemenoff RA, Gitomer B, Chonchol M, Nowak KL. Weight loss to slow cyst growth in autosomal dominant polycystic kidney disease. Cell Reports Metabolism
• Brosnahan GM, Wang W, Gitomer B, Struemph T, George D, You Z, Nowak KL, Klawitter J, Chonchol MB. Metformin Therapy in Autosomal Dominant Polycystic Kidney Disease: A Feasibility Study. Am J Kidney Dis. 2022 Apr;79(4):518-526. doi: 10.1053/j.ajkd.2021.06.026. Epub 2021 Aug 12. PMID: 34391872; PMCID: PMC8837717.
• Nowak KL, Farmer-Bailey H, Cadnapaphornchai MA, You Z, George D, Wang W, Jovanovich A, Soranno DE, Gitomer B, Chonchol M. Curcumin therapy to treat vascular dysfunction in children and young adults with autosomal dominant polycystic kidney disease: Design and baseline characteristics of participants. Contemp Clin Trials Commun. 2020 Aug 12;19:100635. doi: 10.1016/j.conctc.2020.100635. PMID: 33294724; PMCID: PMC7691667.
• Hopp K, Catenacci VA, Dwivedi N, Kline TL, Wang W, You Z, Nguyen DT, Bing K, Poudyal B, Johnson GC, Jackman MR, Miller M, Steele CN, Serkova NJ, MacLean PS, Nemenoff RA, Gitomer B, Chonchol M, Nowak KL. Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease. iScience. 2021 Dec 27;25(1):103697. doi: 10.1016/j.isci.2021.103697. PMID: 35059607; PMCID: PMC8760407.
• Berenice Gitomer, Zhiying You, Godela Brosnahan, Wei Wang, Kristen Nowak, Anna Jovanovich, Arlene Chapman, Ronald Perrone, Theodore Steinman,Vicente Torres, Alan Yu, Michel Chonchol. Antibiotic Use and Kidney Stone Disease in Patients with ADPKD. ASN 2022
• Berenice Gitomer, Zhiying You, Godela Brosnahan, Wei Wang, Katharina Hopp, Kristen Nowak, Arlene Chapman, Ronald Perrone, Theodore Steinman,Vicente Torres, Alan Yu, Michel Chonchol. Systemic Inflammation and Kidney Stone Disease in ADPKD. ASN 2022
• Berenice Gitomer, Wei Wang, Zhiying You, Jessica Ringling, Wei Wang, Kristen Nowak, Anna Jovanovich, Katharina Hopp, Michel Chonchol. Urinary Clusterin and its association with height corrected total kidney volume ADPKD. ANS 2022
• Oh ES, Freeberg KA, Steele CN, Wang W, Farmer-Bailey H, Coppock ME, Seals DR, Chonchol M, Rossman MJ, Craighead DH, Nowak KL. Cerebrovascular pulsatility index is higher in chronic kidney disease. Physiol Rep. 2023 Jan;11(1):e15561. PubMed PMID: 36636757
• Kendrick J, You Z, Andrews E, Farmer-Bailey H, Moreau K, Chonchol M, Steele C, Wang W, Nowak KL, Patel N. Sodium Bicarbonate Treatment and Vascular Function in CKD: A Randomized, Double-Blind, Placebo-Controlled Trial. J Am Soc Nephrol. 2023 Aug 1;34(8):1433-1444. PubMed PMID: 37228030
• Yang X, Wang W, Gitomer B, Cadnapaphornchai MA, Xing F, Chonchol M. Imaging Biomarkers in Young Patients With ADPKD. Kidney Int Rep. 2023 Oct;8(10):2153-2155. PubMed PMID: 37850021
• Steele CN, Oh ES, Wang W, Farmer-Bailey H, Gitomer BY, Chonchol M, Nowak KL. Cerebrovascular Pulsatility Index Is Reduced in Autosomal Dominant Polycystic Kidney Disease. Am J Nephrol. 2023;54(5-6):165-174. PubMed PMID: 37231790
• Wang, W; You, ZY; Steele C; Gitomer, B; Chonchol, M; Nowak, K. Changes in Tubular Biomarkers with Dietary Intervention and Metformin in Patients with Autosomal Dominant Polycystic Kidney Disease. ASN annual meeting, PA, 2023
• Gitomer, B; Wang, W; George , D; Nowak, K; Britz, M; Klawitter, J; Jovanovich, A; You, ZY; Farmer, B and CHonchol, M: Baseline characteristics of participants in the statin therapy in patients with early -stage ADPKD clinical trial. ASN annual meeting PA, 2023