Lisa Kosmiski, MD

Publications

• In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival. Antiviral Therapy 2006
• Resolution of type 2 diabetes mellitus after initiation of potent antiretroviral therapy in an HIV-infected male from Africa. Clinical Infectious Diseases 2006.
• Kosmiski LA, Bessesen DH, Stotz SA, Koeppe JR, Horton TJ. Short-term energy restriction reduces resting energy expenditure in patients with HIV lipodystrophy and hypermetabolism. Metabolism 2007;56:289-295.
• Kosmiski LA, Miller HL, Klemm DJ. In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival. Antivir Ther 2006;11:187-95.
• KoeppeJ, Kosmiski L. Apparent resolution of type 2 diabetes mellitus after initiation of potent antiretroviral therapy in a man from Africa with HIV infection. Clin Infect Dis 2006; 15:
• Kosmiski LA, Bacchetti P, Kotler DP, Heymsfield SB, Lewis CE, Shilpay MG, Scherzer R, Grunfeld C. Relationship of fat distribution with adipokines in human immunodeficiency virus infection. JCEM 2008;93: 216-224.
• Kosmiski LA, Bessesen DH, Stotz S, Koeppe JR, Horton TJ. Short-term overfeeding increases resting energy expenditure in patients with HIV lipodystrophy. Am J Clin Nutr 2007;86:1009-1015.
• IAquilante CL, Bushman LR, Knutesen SD, Rome LC, Kosmiski LA. nfluence of SLCO1B1 and CYP2C8 gene polymorphhisms on rosiglitazone pharmacokinetics in healthy volunteers. Hum Genomics 2008;3:7-16.
• Kosmiski LA, Bacchetti P, Kotler DP, Heymsfield SB, Lewis CE, Shilpak MG, Scherzer R, Grunfeld C. Relationship of fat distribution with adipokines in human immunodeficiency virus infection. J Clin Endocrinol Metab 2008;93:216-2224.
• Scherzer R, Shen W, Bacchetti P, Kotler D, Lewis CE, Shilpak MG, Punyanitya M, Heymsfield SB, Grunfeld C. Study of fat redistribution metabolic change in HIV infection. Comparison of dual-energy x-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjects. Am J CLin Nutr 2008;88:1088-96
• Wohl D, Scherzer R, Heymsfield S, Simberkoff M, Sidney S, Bacchetti P, Grundeld C FRAM STudy Investigators. The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men. J Acquir Immune Diefic Syndr 2008;48: 44-52.
• Aquilante CL, Kosmiski LA, Zineh I, Rome LC, Knutsen SD. Pharmacodynamic effects of rosiglitazone in nondiabetic patients with metabolic syndrome. Pharmacotherapy 2010;30:236-247.
• Kosmiski LA, Ringham BM, Grunwald GK, Bessesen DH. Dual-energy X-ray absoprtiometry modeling to explain the increased resting energy expenditure associated with the HIV lipoatrophy syndrome. Am J Clin Nutr 2009; 90:1525-31.
• Kosmiski, L. Energy expenditure in HIV infection. Am J Clin Nutr; 2011:1677S-1682S.
• Association of increased upper trunk and decreased leg fat with 2-h glucose in control and HIV-infected persons. Diabetes Care 2011;34:2448-53.
• Brown fat activity is not apparent in subjects with HIV lipodystrophy and increased resting energy expenditure. Obesity 2011;19:2096-98.
• Aquilante CL, Kiser JJ, Anderson PL, Chritians U, Kosmiski LA, Daily EB, Hoffman KL, et al. Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunaavir/ritonavir and pravastatin. J Clin Pharm 2011; (EPUB ahead of print)
• McComsey GA, Daar ES, O’Riordan M, Collier AC, Kosmiski L, Santana JL, Fichtenbaum CJ, Fink H, Sax PE, Libutti DE, Gerschenson M. Changes in fat mitochondrial DNA and function in subjects randomized to abacavir-lamivudine or tenofovir DF-emtricitabine with atazanavir-ritonavir or efavirenz:AIDS Clinical Trials Group study A5224s, substudy of A5202. J Infec Dis 2013;207:604-11.
• 22. Aquilante CL, Wempe MF, Sidhom MS, Kosmiski LA. Predhomme JA. Effect of ABCD1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers. Eur J Clin Pharmacol 2013 [Epub ahead of print]
• 21. Aquilante CL, Kiser JJ, Anderson PL, Christians U, Kosmiski LA, Daily EB, Hoffman KL, Hopley CW, Predhomme JA, Schniedewind B, Sidhom MS. Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin. J Clin Pharmacol 2012;52:1725-38.

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000

Hospital Affiliation

• University of Colorado Hospital
• Denver Health Medical Center

Specialty Information

Specialties

• Endocrinology, Diabetes and Metabolism, Board Certification (1995)
• Internal Medicine, Board Certification

Conditions & Treatments

• Endocrine System (Hormones)