Judith Blaine, MD, PhD
Professor, Medicine-Renal Med Diseases/Hypertension

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Medical School:
  • MD, University of Colorado Denver School of Medicine (2001)
Graduate School :
  • PhD, University of Colorado Denver (1999)
Undergraduate School:
  • BA, Harvard University (MA) (1992)
Internship:
  • University of Colorado (University Hospital) Program (2002)
Residency:
  • University of Colorado (University Hospital) Program, Internal Medicine (2004)
Fellowships:
  • University of Colorado (University Hospital) Program, Nephrology (2008)
Languages: English
Department: Medicine-Renal Med Diseases/Hypertension

Publications

  • Haddad G, Dylewski J, Evans R, Lewis L, Blaine J. Knockout of the neonatal Fc receptor alters immune complex trafficking and lysosomal function in cultured podocytes. PLoS One. 2023;18(4):e0284636. PubMed PMID: 37071647
  • Renner B, Laskowski J, Poppelaars F, Ferreira VP, Blaine J, Antonioli AH, Hannan JP, Kovacs JM, van Kooten C, You Z, Pickering MC, Holers VM, Thurman JM. Factor H related proteins modulate complement activation on kidney cells. Kidney Int. 2022 Dec;102(6):1331-1344. PubMed PMID: 36063874
  • Bauer C, Piani F, Banks M, Ordoñez FA, de Lucas-Collantes C, Oshima K, Schmidt EP, Zakharevich I, Segarra A, Martinez C, Roncal-Jimenez C, Satchell SC, Bjornstad P, Lucia MS, Blaine J, Thurman JM, Johnson RJ, Cara-Fuentes G. Minimal Change Disease Is Associated With Endothelial Glycocalyx Degradation and Endothelial Activation. Kidney Int Rep. 2022 Apr;7(4):797-809. PubMed PMID: 35497798
  • Miyazaki-Anzai S, Keenan AL, Blaine J, Miyazaki M. Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification. J Am Soc Nephrol. 2022 Aug;33(8):1477-1486. PubMed PMID: 35459732
  • Kovitangkoon K, Lukkanalikitkul E, Wiangnon P, Chunghom T, Anutrakulchai S, Blaine J, Tonsawan P. Cefazolin Plus Ceftazidime versus Cefazolin Monotherapy in the Treatment of Culture-Negative Peritonitis: A Retrospective Cohort Study. Int J Nephrol Renovasc Dis. 2022;15:17-25. PubMed PMID: 35177925
  • Renner B, Laskowski J, Poppelaars F, Ferreira VP, Blaine J, Antonioli AH, Hannan JP, Kovacs JM, van Kooten C, You Z, Pickering MC, Holers VM, Thurman JM. Factor H related proteins modulate complement activation on kidney cells. Kidney Int. 2022 Dec;102(6):1331-1344. PubMed PMID: 36063874
  • Brown CN, Atwood D, Pokhrel D, Holditch SJ, Altmann C, Skrypnyk NI, Bourne J, Klawitter J, Blaine J, Faubel S, Thorburn A, Edelstein CL. Surgical procedures suppress autophagic flux in the kidney. Cell Death Dis. 2021 Mar 5;12(3):248. PubMed PMID: 33674554
  • Blaine J. Generating a Podocyte-Specific Neonatal F Receptor (FcRn) Knockout Mouse. Methods Mol Biol. 2021;2224:123-132. PubMed PMID: 33606211
  • Dylewski JF, Tonsawan P, Garcia G, Lewis L, Blaine J. Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis. PLoS One. 2020;15(12):e0230401. PubMed PMID: 33370294
  • Dylewski JF, Wilson N, Lu S, Jat P, Weiser-Evans M, Panzer SE, Blaine J. Isolation, purification, and conditional immortalization of murine glomerular endothelial cells of microvascular phenotype. MethodsX. 2020;7:101048. PubMed PMID: 32944514
  • Blaine J, Dylewski J. Regulation of the Actin Cytoskeleton in Podocytes. Cells. 2020 Jul 16;9(7). PubMed PMID: 32708597
  • Skrypnyk NI, Gist KM, Okamura K, Montford JR, You Z, Yang H, Moldovan R, Bodoni E, Blaine JT, Edelstein CL, Soranno DE, Kirkbride-Romeo LA, Griffin BR, Altmann C, Faubel S. IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury. Kidney Int. 2020 May;97(5):966-979. PubMed PMID: 32081304
  • Wilson NA, Dylewski J, Degner KR, O'Neill MA, Reese SR, Hidalgo LG, Blaine J, Panzer SE. An in vitro model of antibody-mediated injury to glomerular endothelial cells: Upregulation of MHC class II and adhesion molecules. Transpl Immunol. 2020 Feb;58:101261. PubMed PMID: 31887408
  • Wilson NA, Dylewski J, Degner KR, O'Neill MA, Reese SR, Hidalgo LG, Blaine J, Panzer SE. An in vitro model of antibody-mediated injury to glomerular endothelial cells: Upregulation of MHC class II and adhesion molecules. Transpl Immunol. 2019 Dec 27;:101261. [Epub ahead of print] PubMed PMID: 31887408
  • Tonsawan P, Dylewski J, Lewis L, Blaine J. Knockout of the neonatal Fc receptor in cultured podocytes alters IL-6 signaling and the actin cytoskeleton. Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C1048-C1060. PubMed PMID: 31553647
  • Dylewski J, Dobrinskikh E, Lewis L, Tonsawan P, Miyazaki M, Jat PS, Blaine J. Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo. PLoS One. 2019;14(2):e0209732. PubMed PMID: 30811433
  • Blaine J, Chonchol M, Levi M. Correction. Renal control of calcium, phosphate, and magnesium homeostasis. Clin J Am Soc Nephrol. 2015 Oct 7;10(10):1886-7. PubMed PMID: 26384363
  • Blaine J, Chonchol M, Levi M. Renal Control of Calcium, Phosphate, and Magnesium Homeostasis. Clin J Am Soc Nephrol. 2014 Oct 6. [Epub ahead of print] PubMed PMID: 25287933
  • Hung KW, Blaine J, Faubel S. Dual therapy difficulties in angiotensin blockade for proteinuria: a teachable moment. JAMA Intern Med. 2014 Sep;174(9):1429-30. PubMed PMID: 25089763
  • Carson JM, Okamura K, Wakashin H, McFann K, Dobrinskikh E, Kopp JB, Blaine J. Podocytes degrade endocytosed albumin primarily in lysosomes. PLoS One. 2014;9(6):e99771. PubMed PMID: 24924335
  • Dobrinskikh E, Okamura K, Kopp JB, Doctor RB, Blaine J. Human podocytes perform polarized, caveolae-dependent albumin endocytosis. Am J Physiol Renal Physiol. 2014 May 1;306(9):F941-51. PubMed PMID: 24573386
  • Dylewski J, Haddad G, Blaine J. Exploiting the neonatal Fc receptor to treat kidney disease. Kidney International, accepted
View All (22 Total) View Less

Professional Memberships

  • American Society of Nephrology, Member
  • American Physiological Society, Member

Practice Locations

UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

UCHealth Anschutz Inpatient Pavilion - Anschutz Medical Campus
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Kidney Disease and Hypertension Clinic - Anschutz Medical Campus
1635 Aurora Ct
Anschutz Outpatient Pavilion, 7th floor
Aurora, CO 80045
720-848-0749

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Internal Medicine, Board Certification (2005)
  • Nephrology, Board Certification (2009)

General Information

Medical Schools:
  • MD, University of Colorado Denver School of Medicine (2001)
Graduate Schools:
  • PhD, University of Colorado Denver (1999)
Undergraduate Schools:
  • BA, Harvard University (MA) (1992)
Internships:
  • University of Colorado (University Hospital) Program (2002)
Residency Programs:
  • University of Colorado (University Hospital) Program, Internal Medicine (2004)
Fellowships:
  • University of Colorado (University Hospital) Program, Nephrology (2008)
Languages: English
Department: Medicine-Renal Med Diseases/Hypertension
SOM Resources
CU Resources
Contact Us
CU Anschutz
Fitzsimons Building
13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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