Joseph Kay, MD

Professional Titles

• UC Denver ACHD Program Director

Recognitions

• Best Doctor for Executives, ColoradoBiz Magazine (2012)
  Named Best Congenital Heart Disease Doctor
• Best Doctors, 5280 Magazine (2015)
  ACHD
• Best Doctors, 5280 Magazine (2016)
  Best ACHD physician in the Denver Metro area
• Best Doctors, 5280 Magazine (2017)
  ACHD
• Best Doctors, 5230 Magazine (2018)
  ACHD
• Community Health Champion Award, Colorado Community Health Centers (2011)
  Recognition for starting and co-directing a volunteer cardiology health clinics in the MCPN network for uninsured people with cardiac issues
• Outstanding Cardiology Faculty Award, Adult Cardiology Fellows (2011)
  For dedication to fellow training

Research Interests

Publications

• Nothing Stated
• Transcatheter septal occlusions in cardiology board review textbook
• International Journal of Cardiology - multicenter research in Adult Congenital Cardiology
• Aortic Pseudoaneurysm Complicating Coarctation Stenting Successfully Treated with a PTFE Balloon Expandable Covered Stent - Congenital Cardiology
• Performance of Cavopulmonary Palliation at Elevated Altitude: Midterm Outcomes and Risk Factors for Failure; Circulation
• Myocardial infarction in a patient with hypoplastic left heart syndrome; case report and review of the literature. - Congenital Cardiology
• On line multi-slice computed tomography interactive overlay with conventional X-ray: A new and advance imaging fusion concept. International Journal of Cardiology , published online January 29, 2008
• Outcome of Pulmonary Replacement in Adults After Tetralogy Repair; A Mulit-Institutional Study; Congenital Heart Disease. 3(3)162-167. 2008 June
• Aortic Pseudo Aneurysm Complicating Coarctation Stenting Successfully Treated with a PTFE Balloon Expandable Covered Stent: Congenital Heart Disease 2008;3:209-212
• Acute Myocardial Infarction 17 years After the Norwood. Anticoagulation in Fontan Patients Revisited. (Congenital Cardiology 2008, Accepted- In press )
• Performance of Cavopulmonary Palliation at Elevated Altitude: Midterm Outcomes and Risk Factors for Failure. Circulation. 2008 Sep 30;118(14 Suppl):S177-81
• . Multicenter Research in Adult Congenital Heart Disease; International Journal of Cardiology: Sept 26 2008;129(2):155-159
• Sildenafil Increases Systemic Saturation and Reduces Pulmonary Artery Pressure in Patients with Failing Fontan Physiology Congenital Heart Disease: Clinical Studies From Fetus to Adulthood. Congenital Heart Disease , Accepted Oct 2008 .
• Anomalous Left Anterior Descending Coronary Artery from the Pulmonary Artery, Unroofed Coronary Sinus, Patent Foramen Ovale, and a Persistent Left-sided SVC in a Single Patient; A Harmonious Quartet of Defects_Congenital Heart Disease March/April; 2009;4: 120-125
• A Case Report of a Baffle-Leak Closure using Real Time 3-D Transesophageal Guidance. European Journal of Echocardiography; Published online January 23, 2009
• Prevalence of Left Ventricular Systolic Dysfunction in Adults with Repaired Tetralogy of Fallot (TOF). Oral presentation. American College of Cardiology, Orlando FL March 2009
• Abnormal left ventricular Doppler parameters in adults with repaired tetralogy of Fallot. Poster presentation. American College of Cardiology. Orlando Florida March 2009
• Heart Rate Response during Exercise as a Predictor of Pregnancy Outcome in Women with Congenital Heart Disease , Circulation (in review)
• Catheter Closure of Intracardiac Shunts; Mayo Cardiology Review
• Heart Rate Response during Exercise as a Predictor of Pregnancy Outcome in Women with Congenital Heart Disease. AHA, Oral presentation. Orlando FL, Nov 2009
• Paul Khairy, Craig Broberg, Jamil Abuoulhosn, Micheal Earing, Deborah Gersony, Carole Warnes, Alexander Opotowsky, François-Pierre Mongeon, Michelle Nickolaus, Anne Marie Valente , Michael Landzberg, Michelle Gurvitz, , Stephen Cook, Joseph Kay, Jennifer Ting, Gary Webb: Arrhythmia Burden in Adults with Surgically Repaired Tetralogy of FalloT: A Multi-Institutional Study. Circulation 2010;122;868-875.
• Quaife RA. Chen MY. Kim M. Klein AJ. Jehle A. Kay J. Groves BM. Carroll JD. Pre-procedural planning for percutaneous atrial septal defect closure: transesophageal echocardiography compared with cardiac computed tomographic angiography. Journal of cardiovascular computed tomography. 4(5):330-8, 2010 Sep-Oct.
• Lui GK. Silversides CK. Khairy P. Fernandes SM. Valente AM. Nickolaus MJ. Earing MG. Aboulhosn JA. Rosenbaum MS. Cook S. Kay JD. Jin Z. Gersony DR. Alliance for Adult Research in Congenital Cardiology (AARCC). Heart rate response during exercise and pregnancy outcome in women with congenital heart disease. Circulation. 123(3):242-8, 2011 Jan 25.
• Fasen, GS; Gupta, R; Smith, ML; Burton, J; Kay, J. Incidence of Hepatic Fibrosis and Cirrhosis in Patients after Fontan Palliation European Society of Cardiology, Poster. Stolkholm, Sweden, Aug 2010.
• Joshua Sticka, MD, Jeremy Nicholarsen, MD, Brian Fonseca, MD, Robert Quaife, MD, Joseph Kay, MD.Comparison of Doppler echocardiography derived right ventricular function to cardiac magnetic resonance imaging derived ejection fraction in children and adults with congenital pulmonary valve disease. Western Society of Pediatric Cardiology, Poster, Phenoix AZ, April 2010
• Catheter Closure of IntraCardiac Shunts. Mayo Cardiology Review. (In production- Anticipated publication date summer 2010)
• Dorosz, J, Kay J A Sinus Venosus Atrial Septal Defect is Diagnosed by Echocardiography with an Unusual Bubble Study. Echocardiography 2013 (accepted 2/10/13)
• Aboulhosn JA, Lluri G, Gurvitz MZ, Khairy P, Mongeon FP, Kay J, Valente AM, Earing MG, Opotowsky AR, Lui G, Gersony DR, Cook S, Child J, Ting J, Webb G, Landzberg M, Broberg CS; Alliance for Adult Research in Congenital Cardiology (AARCC). Left and right ventricular Diastolic Function in Adults with Repaired Tetralogy of Fallot: A Multi-Institutional Study. Can J Cardiol. 2013 Jan 28. doi:pii: S0828-282X(12)01453-5. 10.1016/j.cjca.2012.11.003. [Epub ahead of print]
• François-Pierre Mongeon MD, SM1; Michelle Z. Gurvitz, MD; Craig S. Broberg MD; Jamil Aboulhosn, MD; Alexander R. Opotowsky, MD, MS;, Joseph Kay, MD; Anne Marie Valente, MD; Michael G. Earing, MD; George K. Lui, MD; Susan M. Fernandes, MPH, PA-C ; Deborah R. Gersony, MD; Stephen Cook, MD; Jennifer Grando Ting, MD; Michelle J. Nickolaus, CRNP; Michael J. Landzberg, MD; Paul Khairy, MD, PhD from the Alliance for Adult Research in Congenital Cardiology (AARCC), Aortic root dilatation in adults with surgically repaired tetralogy of Fallot: a multicenter a cross-sectional study. Circulation. 2013 Jan 15;127(2):172-9. doi: 10.1161/CIRCULATIONAHA.112.129585. Epub 2012 Dec 6.
• Kay, Joseph, Khanna, Amber – Late Sequale in Adults with congenital heart disease; Pediatric Cardiology, Cardiac Surgery, & Intensive Carre; Springer (anticipated 2013)
• Jsoeph Kay MD, Amber Khanna MD, Emily Rucdeschel MD ; L-TGA ; Color Atlas and Synopsis of Pediatric and Congenital Cardiology; McGraw Hill
• 1. Cotts T, Khairy P, Opotowsky AR, John AS, Valente AM, Zaidi AN, Cook SC, Aboulhosn J, Ting JG, Gurvitz M, Landzberg MJ, Verstappen A, Kay J, Earing M, Franklin W, Kogon B, Broberg CS; for the Alliance for Adult Research in Congenital Cardiology (AARCC). Clinical research priorities in adult congenital heart disease. Int J Cardiol. 2013 Dec 24. pii: S0167-5273(13)02244-4. doi: 10.1016/j.ijcard.2013.12.034.
• 2. Valente, Anne Marie, Aboulhosn JA, Lluri G, Gurvitz MZ, Khairy P, Mongeon FP, Kay J, Earing MG, Opotowsky AR, Lui G, Gersony DR, Cook S, Child J, Ting J, Webb G, Landzberg M, Broberg CS; Alliance for Adult Research in Congenital Cardiology (AARCC). : Improving Heart Disease Knowledge and Research Participation in Adults with Congenital Heart Disease (The Health, Education and Access Research Trial: HEART-ACHD). International Journal of Cardiology Int J Cardiol. 2013 May 4. doi:pii: S0167-5273(13)00588-3. 10.1016/j.ijcard.2013.04.004
• 3. Michelle Gurvitz MD, Anne Marie Valente MD, Craig Borberg MD, Stephen Cook MD, Karen Stout MD, Joseph Kay MD, Jennifer Ting MD, Karen Kuehl MD, Micheal Earing MD, Gary Webb MD, Linda Houser APN, Alexander Opotowsky MD, Amy Harmon BA, Dionne Graham PhD, Paul Khairy MD, Ann Gianola MA, Amy Verstappenm MED, Michael Landzberg MD, for the Alliance for Adult Research in Congenital Cardiology (AARCC) and for Adult Congenital Heart Association. Prevalence and Predictors of Gaps in Care Among Adult Congenital Heart Disease Patients p HEART-ACHD (The Health, Education, and Access Research Trial): JACC 2013; Vol 61(21):2180-4
• 4. Dorosz, J, Kay J A Sinus Venosus Atrial Septal Defect is Diagnosed by Echocardiography with an Unusual Bubble Study. Echocardiography 2013 (accepted 2/10/13)
• 5. Aboulhosn JA, Lluri G, Gurvitz MZ, Khairy P, Mongeon FP, Kay J, Valente AM, Earing MG, Opotowsky AR, Lui G, Gersony DR, Cook S, Child J, Ting J, Webb G, Landzberg M, Broberg CS; Alliance for Adult Research in Congenital Cardiology (AARCC). Left and right ventricular Diastolic Function in Adults with Repaired Tetralogy of Fallot: A Multi-Institutional Study. Can J Cardiol. 2013 Jan 28. doi:pii: S0828-282X(12)01453-5. 10.1016/j.cjca.2012.11.003. [Epub ahead of print]
• 6. François-Pierre Mongeon MD, SM1; Michelle Z. Gurvitz, MD; Craig S. Broberg MD; Jamil Aboulhosn, MD; Alexander R. Opotowsky, MD, MS;, Joseph Kay, MD; Anne Marie Valente, MD; Michael G. Earing, MD; George K. Lui, MD; Susan M. Fernandes, MPH, PA-C ; Deborah R. Gersony, MD; Stephen Cook, MD; Jennifer Grando Ting, MD; Michelle J. Nickolaus, CRNP; Michael J. Landzberg, MD; Paul Khairy, MD, PhD from the Alliance for Adult Research in Congenital Cardiology (AARCC), Aortic root dilatation in adults with surgically repaired tetralogy of Fallot: a multicenter a cross-sectional study. Circulation. 2013 Jan 15;127(2):172-9. doi: 10.1161/CIRCULATIONAHA.112.129585. Epub 2012 Dec 6.
• Kay, Joseph, Khanna, Amber – Late Sequale in Adults with congenital heart disease; Pediatric Cardiology, Cardiac Surgery, & Intensive Carre; Springer (anticipated 2013)
• Ruckdeschel, Emily, Kay, Joseph D – Pulmonary Regurgitation and Management Challenges in the Adult with Tetralogy of Fallot. Current Treatment options in Cardiology (anticipated 2014)
• Cedars AM, Schmidt AS, Broberg C, Zaidi A, Opotowsky A, Grewal J, Kay J, Bhatt AB, Novak E, Spertus J; Adult Congenital Heart Disease Patients Experience Similar Symptoms of Disease Activity. Circ Cardiovasc Qual Outcomes Alliance for Adult Research in Congenital Cardiology (AARCC). 2016 Mar;9(2):161-70. Doi 10.1161/CIRCOUTCOMES.115.002154. Epub 2016 Mar 8. PMID: 26957518
• Wiktor DM, Kay JD, Kim MS. Consecutive percutaneous valve-in-valve replacement late after Ross procedure: A novel approach in an adult with congenital heart disease. Catheter Cardiovasc Interv. 2015 Nov 15;86(6):1092-6. doi: 10.1002/ccd.26114. Epub 2015 Sep 10. PMID: 2635613
• Kollengode M, Khanna A, Kay J. Optimal timing for pulmonary valve replacement in severe pulmonic regurgitation revisited. Journal of the American College of Cardiology 2016;16:1130.
• Khanna AD, Duca L, Kao D, Kay J, Crume T. Non-cardiac surgery in adults with congenital heart disease. International Symposium on Congenital Heart Disease in the Adult. 2016.
• Nicolarsen, J., Oestreich, B., Patel, S., Aboulhosn, J., Franklin, W., Hageman, A., Kloudas, L., Paruchuri, V., Ruckdeschel, E., Rutz, J., Yeung, E., Khanna, A., and Kay, J. High altitude is not associated with pulmonary arterial hypertension in adult patients with atrial septal defects. 26th Annual Conference of the Western Society of Pediatric Cardiology, Vail, CO. March 2015.
• Jensen, K., Seewald, L., Levitt, M., McCabe, E., Hickey, F., Nicolarsen, J., Kay, J., and Khanna, A. Cardiac valve disease in adults with Down Syndrome. SGIM 38th Annual Meeting Toronto, CA. April 2015.
• Liang JJ, Frankel DS, Parikh V, Lakkireddy D, Mohanty S, Burkhardt JD, Natale A, Szilagyi J, Gerstenfeld EP, Moore JP, Collins KK, Kay JD, Santangeli P, Marchlinski FE, Sauer WH, Nguyen DT. Safety and Outcomes of Catheter Ablation for Atrial Fibrillation in Adults with Congenital Heart Disease: A Multicenter Registry Study. Heart Rhythm. 2018 Dec 26. [Epub ahead of print] PubMed PMID: 30593868
• Morgan GJ, Sadeghi S, Salem MM, Wilson N, Kay J, Rothman A, Galindo A, Martin MH, Gray R, Ross M, Aboulhosn JA, Levi DS. SAPIEN valve for percutaneous transcatheter pulmonary valve replacement without "pre-stenting": A multi-institutional experience. Catheter Cardiovasc Interv. 2018 Oct 23. [Epub ahead of print] PubMed PMID: 30351525
• Sandhu A, Ruckdeschel E, Sauer WH, Collins KK, Kay JD, Khanna A, Jaggers J, Campbell D, Mitchell M, Nguyen DT. Perioperative electrophysiology study in patients with tetralogy of Fallot undergoing pulmonary valve replacement will identify those at high risk of subsequent ventricular tachycardia. Heart Rhythm. 2018 May;15(5):679-685. PubMed PMID: 29330130
• Mandell MS, Kay J. High-Sensitivity Troponins in Liver Transplantation: How Will They Change Our Practice?. Transplantation. 2018 May;102(5):716-717. PubMed PMID: 29329186
• Deshaies C, Hamilton RM, Shohoudi A, Trottier H, Poirier N, Aboulhosn J, Broberg CS, Cohen S, Cook S, Dore A, Fernandes SM, Fournier A, Kay J, Mondésert B, Mongeon FP, Opotowsky AR, Proietti A, Ting J, Zaidi A, Khairy P. Thromboembolic Risk After Atriopulmonary, Lateral Tunnel, and Extracardiac Conduit Fontan Surgery. J Am Coll Cardiol. 2019 Aug 27;74(8):1071-1081. PubMed PMID: 31439217
• Khanna AD, Duca LM, Kay JD, Shore J, Kelly SL, Crume T. Prevalence of Mental Illness in Adolescents and Adults With Congenital Heart Disease from the Colorado Congenital Heart Defect Surveillance System. Am J Cardiol. 2019 Aug 15;124(4):618-626. PubMed PMID: 31303246
• Yang J, Brunnquell M, Liang JJ, Callans DJ, Garcia FC, Lin D, Frankel DS, Kay J, Marchlinski FE, Tzou W, Sauer WH, Liu B, Ruckdeschel ES, Collins K, Santangeli P, Nguyen DT. Long term follow-up after ventricular tachycardia ablation in patients with congenital heart disease. J Cardiovasc Electrophysiol. 2019 Sep;30(9):1560-1568. PubMed PMID: 31111602
• Liang JJ, Frankel DS, Parikh V, Lakkireddy D, Mohanty S, Burkhardt JD, Natale A, Szilagyi J, Gerstenfeld EP, Moore JP, Collins KK, Kay JD, Santangeli P, Marchlinski FE, Sauer WH, Nguyen DT. Safety and outcomes of catheter ablation for atrial fibrillation in adults with congenital heart disease: A multicenter registry study. Heart Rhythm. 2019 Jun;16(6):846-852. PubMed PMID: 30593868
• Morgan GJ, Sadeghi S, Salem MM, Wilson N, Kay J, Rothman A, Galindo A, Martin MH, Gray R, Ross M, Aboulhosn JA, Levi DS. SAPIEN valve for percutaneous transcatheter pulmonary valve replacement without "pre-stenting": A multi-institutional experience. Catheter Cardiovasc Interv. 2019 Feb 1;93(2):324-329. PubMed PMID: 30351525
• Sandhu A, Ruckdeschel E, Sauer WH, Collins KK, Kay JD, Khanna A, Jaggers J, Campbell D, Mitchell M, Nguyen DT. Perioperative electrophysiology study in patients with tetralogy of Fallot undergoing pulmonary valve replacement will identify those at high risk of subsequent ventricular tachycardia. Heart Rhythm. 2018 May;15(5):679-685. PubMed PMID: 29330130
• Biswas M, Sandhu A, Kay JD, Khanna AD, Collins KK, Sauer WH, Nguyen DT. Patients with bicuspid aortic valves may be associated with infra-hisian conduction disease requiring pacemakers. J Interv Card Electrophysiol. 2020 May 26. [Epub ahead of print] PubMed PMID: 32458178
• Purohit SN, Lee PJ, Strobel AL, Desai AA, Marsala MT, Bull TM, Brieke A, Vargas D, Kay JD, Altman NL. Unusual Case of Acquired Hypoxemia Following Left Ventricular Assist Device Implantation. Circ Heart Fail. 2020 Jan;13(1):e006394. PubMed PMID: 31896269
• Cg S, Rm J, Ad K, E Y, M K, G M, J K. Prevalence of Sleep-Disordered Breathing in a Cohort of Adult Fontan Patients. Pediatr Cardiol. 2020 Oct;41(7):1438-1444. PubMed PMID: 32577770
• Aboulhosn JA, Hijazi ZM, Kavinsky CJ, McElhinney DB, Asgar AW, Benson LN, Daniels CJ, Ghobrial J, Horlick E, Ing FF, Inglessis I, Kay J, Levi DS. SCAI position statement on adult congenital cardiac interventional training, competencies and organizational recommendations. Catheter Cardiovasc Interv. 2020 Sep 1;96(3):643-650. PubMed PMID: 32272495
• https://www.ncbi.nlm.nih.gov/pubmed/34143227
• O'Callaghan B, Zablah J, Leahy R, Shorofsky M, Kay J, Morgan G. Contrast-free percutaneous pulmonary valve replacement: a safe approach for valve-in-valve procedures. Postepy Kardiol Interwencyjnej. 2021 Jun;17(2):200-209. PubMed PMID: 34400923
• Basmaji S, Samuel M, Shohoudi A, Hamilton RM, Aboulhosn J, Broberg CS, Chaix MA, Cohen S, Cook S, Dore A, Fernandes SM, Fortier A, Fournier A, Guertin MC, Kay J, Mondésert B, Mongeon FP, Opotowsky AR, Proietti A, Ting J, Zaidi A, Khairy P. Time in Therapeutic Range With Vitamin K Antagonists in Congenital Heart Disease: A Multicentre Study. Can J Cardiol. 2022 Nov;38(11):1751-1758. PubMed PMID: 35964887
• Broberg CS, van Dissel A, Minnier J, Aboulhosn J, Kauling RM, Ginde S, Krieger EV, Rodriguez F 3rd, Gupta T, Shah S, John AS, Cotts T, Kay WA, Kuo M, Dwight C, Woods P, Nicolarsen J, Sarubbi B, Fusco F, Antonova P, Fernandes S, Grewal J, Cramer J, Khairy P, Gallego P, O'Donnell C, Hannah J, Dellborg M, Rodriguez-Monserrate CP, Muhll IV, Pylypchuk S, Magalski A, Han F, Lubert AM, Kay J, Yeung E, Roos-Hesselink J, Baker D, Celermajer DS, Burchill LJ, Wilson WM, Wong J, Kutty S, Opotowsky AR. Long-Term Outcomes After Atrial Switch Operation for Transposition of the Great Arteries. J Am Coll Cardiol. 2022 Sep 6;80(10):951-963. PubMed PMID: 36049802

Professional Memberships

• American College of Cardiology, Fellow

Practice Locations

• University of Colorado Hospital
• Children's Hospital Colorado

Specialty Information

• Pediatric Cardiology, Board Certification (2004)
• Internal Medicine, Board Certification (2006)
• General Cardiology, Board Certification (2003)
• Cardiology, Board Certification (2003, 2024)
• Adult Congenital Heart Disease, Board Certification (2015)

• Heart and Circulation
• Heart and Circulation - Congenital Heart Disease
• Heart and Circulation - Heart Valve Diseases
• Heart and Circulation - Adult Congenital Heart Disease