Bifeng Gao, PhD, MS

Publications

• Effects of Dietary Energy Restriction on Gene Regulation in Mammary Epithelial Cells. Zongjian Zhu, Weiqin Jiang, John N. McGinley, Jennifer M. Price, Bifeng Gao, and Henry J. Thompson. Cancer Res 2007; 67: (24). December 15, 2007
• Nagel MA, Gilden D, Shade T, Gao B, Cohrs RJ. Rapid and sensitive detection of 68 unique varicella zoster virus gene transcripts in five multiplex reverse transcription-polymerase chain reactions. J Virol Methods. 2009 Apr;157(1):62-8. Epub 2009 Jan 7.
• Ren Q, Yang H, Gao B, Zhang Z. Global transcriptional analysis of yeast cell death induced by mutation of sister chromatid cohesin. Comp Funct Genomics. 2008: 634283.
• Green RM, Gally F, Keeney JG, Alper S, Gao B, et al. (2009) Impact of Cigarette Smoke Exposure on Innate Immunity: A Caenorhabditis elegans Model. PLoS ONE 4(8): e6860. doi:10.1371/journal.pone.0006860
• Nagel MA, Gilden D, Shade T, Gao B, Cohrs RJ. Rapid and sensitive detection of 68 unique varicella zoster virus gene transcripts in five multiplex reverse transcription-polymerase chain reactions. J Virol Methods. 2009 Apr;157(1):62-8. Epub 2009 Jan 7.
• Ann Olincy,Robert House,Bifeng Gao,Peter Recksiek,Tzu Lip Phang,Bernadette Sullivan,Jeff P. Hollis, Janet Hopkins,Ted Shade,Michael G Edwards,Ruby Vianzon,Cory Griffiths,John Ceilley,Roger W. Helfrich,Jonathan Ritvo,Erica Weis,David Weiss,Judith Gault, Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia, TRANSLATIONAL BIOMEDICINE 2011 Vol. 2 No. 1:4
• Wang J, Nikrad MP, Phang T, Gao B, Alford T, Ito Y, Edeen K, Travanty EA, Kosmider B, Hartshorn K, Mason RJ. Am J Respir Cell Mol Biol. 2011 Jan 14. [Epub ahead of print]
• 1. Wang J, Nikrad MP, Phang T, Gao B, Alford T, Ito Y, Edeen K, Travanty EA, Kosmider B, Hartshorn K, Mason RJ. Innate Immune Response to Influenza A Virus in Differentiated Human Alveolar Type II cells. Am J Respir Cell Mol Biol. 2011 Sept., Vol 45(3): 582-91.
• Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM. Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension. Am J Respir Cell Mol Biol. 2013 Dec;49(6):951-9. PubMed PMID: 23815102
• Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions. Cancer Prev Res (Phila). 2014 Feb;7(2):255-65. PubMed PMID: 24346345
• 2. Ann Olincy, Robert House, Bifeng Gao, Peter Recksiek, Tzu Lip Phang, Bernadette Sullivan, Jeff P. Hollis, Janet Hopkins, Ted Shade, Michael G Edwards, Ruby Vianzon, Cory Griffiths, John Ceilley, Roger W. Helfrich, Jonathan Ritvo, Erica Weis, David Weiss, Judith Gault, Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia. Translational Biomedicine, 2011, Vol. 2 No. 1:4; doi: 10: 3823/421.
• LU Wen-li, FANG Zhao-qin, PAN Zhi-qiang, LIU Xiao-mei, LIANG Chao, WU Zhong-hua, GAO Bi-feng. Transcription of oxidative phosphorylation pathway genes in thyroid of mice with normal qi deficiency syndrome. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 2011, Vol. 17(3): 264-6.
• 1. Wang J, Nikrad MP, Travanty EA, Zhou B, Phang T, Gao B, Alford T, Ito Y, Nahreini P, Hartshorn K, Wentworth D, Dinarello CA, Mason RJ. Innate immune response of human alveolar macrophages during influenza A infection. PLoS One. 2012;7(3):e29879. doi: 10.1371/journal.pone.0029879. Epub 2012 Mar 2.
• 2. Wang J, Nikrad MP, Phang T, Gao B, Alford T, Ito Y, Edeen K, Travanty EA, Kosmider B, Hartshorn K, Mason RJ. Innate Immune Response to Influenza A Virus in Differentiated Human Alveolar Type II cells. Am J Respir Cell Mol Biol. 2011 Sept., Vol 45(3): 582-91.
• Ito Y, Zemans R, Correll K, Yang IV, Ahmad A, Gao B, Mason RJ. Stanniocalcin-1 is induced by hypoxia inducible factor in rat alveolar epithelial cells. Biochem Biophys Res Commun. 2014 Oct 3;452(4):1091-7. PubMed PMID: 25251473
• Gao B, Doan A, Hybertson BM. The clinical potential of influencing Nrf2 signaling in degenerative and immunological disorders. Clin Pharmacol. 2014;6:19-34. PubMed PMID: 24520207
• Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions. Cancer Prev Res (Phila). 2014 Feb;7(2):255-65. PubMed PMID: 24346345
• 3. Ann Olincy, Robert House, Bifeng Gao, Peter Recksiek, Tzu Lip Phang, Bernadette Sullivan, Jeff P. Hollis, Janet Hopkins, Ted Shade, Michael G Edwards, Ruby Vianzon, Cory Griffiths, John Ceilley, Roger W. Helfrich, Jonathan Ritvo, Erica Weis, David Weiss, Judith Gault, Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia. Translational Biomedicine, 2011, Vol. 2 No. 1:4; doi: 10: 3823/421.
• 4. Hybertson BM, Gao B, Bose SK, McCord JM. Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation. Mol Aspects Med. 2011 Aug;32(4-6):234-46. doi: 10.1016/j.mam.2011.10.006. Epub 2011 Oct 15. Review.
• Chen Z, Gowan K, Leach SM, Viboolsittiseri SS, Mishra AK, Kadoishi T, Diener K, Gao B, Jones K, Wang JH. Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing. BMC Genomics. 2016 Oct 21;17(1):823. PubMed PMID: 27769169
• Soto SM, Blake AC, Wesolowski SR, Rozance PJ, Barthels KB, Gao B, Hetrick B, McCurdy CE, Garza NG, Hay WW Jr, Leinwand LA, Friedman JE, Brown LD. Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro. J Endocrinol. 2017 Mar;232(3):475-491. PubMed PMID: 28053000
• Goldstein NB, Koster MI, Jones KL, Gao B, Hoaglin LG, Robinson SE, Wright MJ, Birlea SI, Luman A, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Repigmentation of Human Vitiligo Skin by NBUVB is Controlled by Transcription of GLI1 and Activation of ß-Catenin Pathway in the Hair Follicle Bulge Stem Cells. J Invest Dermatol. 2017 Oct 17. [Epub ahead of print] PubMed PMID: 29054607
• Soto SM, Blake AC, Wesolowski SR, Rozance PJ, Barthel KB, Gao B, Hetrick B, McCurdy CE, Garza NG, Hay WW Jr, Leinwand LA, Friedman JE, Brown LD. Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro. J Endocrinol. 2017 Mar;232(3):475-491. PubMed PMID: 28053000
• Goldstein NB, Koster MI, Jones KL, Gao B, Hoaglin LG, Robinson SE, Wright MJ, Birlea SI, Luman A, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the ß-Catenin Pathway in the Hair Follicle Bulge Stem Cells. J Invest Dermatol. 2018 Mar;138(3):657-668. PubMed PMID: 29054607
• Simenauer A, Assefa B, Rios-Ochoa J, Geraci K, Hybertson B, Gao B, McCord J, Elajaili H, Nozik-Grayck E, Cota-Gomez A. Repression of Nrf2/ARE regulated antioxidant genes and dysregulation of the cellular redox environment by the HIV Transactivator of Transcription. Free Radic Biol Med. 2019 Sep;141:244-252. PubMed PMID: 31238128
• Kukoyi AT, Fan X, Staitieh BS, Hybertson BM, Gao B, McCord JM, Guidot DM. MiR-144 mediates Nrf2 inhibition and alveolar epithelial dysfunction in HIV-1 transgenic rats. Am J Physiol Cell Physiol. 2019 Aug 1;317(2):C390-C397. PubMed PMID: 31091144
• Hybertson BM, Gao B, Bose S, McCord JM. Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular Protection against Oxidative Injury. Antioxidants (Basel). 2019 May 3;8(5). PubMed PMID: 31058853
• Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zheng X, Gao B, Xiao SY, Chen W, Ma C, Farrar C, Zhu C, Chan OTM, Xin C, Winnicki A, Winnicki J, Tang M, Park R, Winnicki M, Diener K, Wang Z, Liu Q, Chu CH, Arter ZL, Yue P, Alpert L, Hui GS, Fei P, Turkson J, Yang W, Wu G, Tao A, Ramos JW, Moisyadi S, Holcombe RF, Jia W, Birnbaumer L, Zhou X, Chu WM. GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2. Gastroenterology. 2019 Jun;156(8):2297-2312. PubMed PMID: 30836096
• Goldstein NB, Steel A, Barbulescu CC, Koster MI, Wright MJ, Jones KL, Gao B, Ward B, Woessner B, Trottier Z, Pakieser J, Hu J, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling. J Invest Dermatol. 2020 Aug 13. [Epub ahead of print] PubMed PMID: 32800877
• Agostini M, Hininger-Favier I, Marcourt L, Boucherle B, Gao B, Hybertson BM, Bose SK, McCord JM, Millery A, Rome M, Ferreira Queiroz E, Wolfender JL, Gallet C, Boumendjel A. Phytochemical and Biological Investigation of Helianthemum nummularium, a High-Altitude Growing Alpine Plant Overrepresented in Ungulates Diets. Planta Med. 2020 Nov;86(16):1185-1190. PubMed PMID: 32645735
• McCord JM, Hybertson BM, Cota-Gomez A, Geraci KP, Gao B. Nrf2 Activator PB125(®) as a Potential Therapeutic Agent against COVID-19. Antioxidants (Basel). 2020 Jun 12;9(6). PubMed PMID: 32545518
• McCord JM, Hybertson BM, Cota-Gomez A, Gao B. Nrf2 activator PB125® as a carnosic acid-based therapeutic agent against respiratory viral diseases, including COVID-19. Free Radic Biol Med. 2021 Nov 1;175:56-64. PubMed PMID: 34058321
• Goldstein NB, Steel A, Barbulescu CC, Koster MI, Wright MJ, Jones KL, Gao B, Ward B, Woessner B, Trottier Z, Pakieser J, Hu J, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling. J Invest Dermatol. 2021 Mar;141(3):638-647.e13. PubMed PMID: 32800877
• Heinzelmann K, Hu Q, Hu Y, Dobrinskikh E, Ansari M, Melo-Narváez MC, Ulke HM, Leavitt C, Mirita C, Trudeau T, Saal ML, Rice P, Gao B, Janssen WJ, Yang IV, Schiller HB, Vladar EK, Lehmann M, Königshoff M. Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis. Eur Respir J. 2022 Jun;59(6). PubMed PMID: 35604813
• Campbell NV, Mickael C, Kumar S, Zhang H, Campbell IL, Gillen AE, Trentin CO, Diener K, Gao B, Kheyfets VO, Gu S, Kumar R, Phang T, Brown RD, Graham BB, Stenmark KR. Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1;323(1):L58-L68. PubMed PMID: 35608266
• Hybertson BM, Gao B, McCord JM. Effects of the Phytochemical Combination PB123 on Nrf2 Activation, Gene Expression, and the Cholesterol Pathway in HepG2 Cells. OBM Integr Compliment Med. 2022;7(1). PubMed PMID: 35252766
• Teniou, S., Bensegueni, A., Hybertson, B.M., Gao, B., Bose, S.K., McCord, J.M., Chovelon, B., Bensouici, C., Boumendjel, A., Hininger-Favier, I.Hide details Biodriven investigation of the wild edible mushroom Pleurotus eryngii revealing unique properties as functional food Journal of Functional Foods, Volume 89, February 2022
• McCord JM, Gao B, Hybertson BM. The Complex Genetic and Epigenetic Regulation of the Nrf2 Pathways: A Review. Antioxidants (Basel). 2023 Feb 3;12(2). PubMed PMID: 36829925

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Specialty Information

Specialties

• Psychology