Laurie Gaspar, MD

Professional Titles

• Former Chair
• Professor

Recognitions

• Best Doctors in America, Best Doctors (2006)
  
• Best Doctors in America, Best Doctors (2008)
  
• Best Doctors in America, Best Doctors (2010)
  
• Top Doctors Denver, 5280 (2006)
  
• Best Doctors in America, Best Doctors (2012)
  
• Best Doctors in America, Best Doctors (2015)
• America's Best Physicians, America's Best Physicians (2016)

Publications

• Gan GN, Weickhardt AJ, Scheier B, Doebele RC, Gaspar LE, Kavanagh BD, Camidge DR. Stereotactic Radiation Therapy can Safely and Durably Control Sites of Extra-Central Nervous System Oligoprogressive Disease in Anaplastic Lymphoma Kinase-Positive Lung Cancer Patients Receiving Crizotinib. Int J Radiat Oncol Biol Phys. 2014 Jan 22. [Epub ahead of print] PubMed PMID: 24462383
• Chen Y, Moon J, Pandya KJ, Lau DH, Kelly K, Hirsch FR, Gaspar LE, Redman M, Gandara DR. A Pilot Study (SWOG S0429) of Weekly Cetuximab and Chest Radiotherapy for Poor-Risk Stage III Non-Small Cell Lung Cancer. Front Oncol. 2013;3:219. PubMed PMID: 24010120
• Lin NU, Wefel JS, Lee EQ, Schiff D, van den Bent MJ, Soffietti R, Suh JH, Vogelbaum MA, Mehta MP, Dancey J, Linskey ME, Camidge DR, Aoyama H, Brown PD, Chang SM, Kalkanis SN, Barani IJ, Baumert BG, Gaspar LE, Hodi FS, Macdonald DR, Wen PY, Response Assessment in Neuro-Oncology (RANO) group. Challenges relating to solid tumour brain metastases in clinical trials, part 2: neurocognitive, neurological, and quality-of-life outcomes. A report from the RANO group. Lancet Oncol. 2013 Sep;14(10):e407-16. PubMed PMID: 23993385
• Lin NU, Lee EQ, Aoyama H, Barani IJ, Baumert BG, Brown PD, Camidge DR, Chang SM, Dancey J, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Lamborn KR, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wefel JS, Wen PY, Response Assessment in Neuro-Oncology (RANO) group. Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group. Lancet Oncol. 2013 Sep;14(10):e396-406. PubMed PMID: 23993384
• Rusthoven CG, Yeh N, Gaspar LE. Radiation Therapy for Oligometastatic Non-Small Cell Lung Cancer: Theory and Practice. Cancer J. 2015 Sep-Oct;21(5):404-12. PubMed PMID: 26389766
• Compton JJ, Gaspar LE, Shrieve DC, Wilson LD, Griem KL, Amdur RJ, Lee WR. Resident-reported brachytherapy experience in ACGME-accredited radiation oncology training programs. Brachytherapy. 2013 Nov-Dec;12(6):622-7. PubMed PMID: 23973187
• Reddy K, Gaspar LE, Kavanagh BD, Waziri A, Damek DM, Ney D, Lillehei KO, Chen C. Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide. J Neurooncol. 2013 Aug;114(1):111-6. PubMed PMID: 23729276
• Amin NP, Miften M, Thornton D, Ryan N, Kavanagh B, Gaspar LE. Effect of induction chemotherapy on estimated risk of radiation pneumonitis in bulky non-small cell lung cancer. Med Dosim. 2013 Autumn;38(3):320-6. PubMed PMID: 23611631
• Sperduto PW, Kased N, Roberge D, Chao ST, Shanley R, Luo X, Sneed PK, Suh J, Weil RJ, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer. J Neurooncol. 2013 May;112(3):467-72. PubMed PMID: 23462853
• ACR–ABS Practice parameter for electronically-generated, low-energy radiation sources (ELS) available on the ACR website at: http://www.acr.org/~/media/ACR/Documents/PGTS/guidelines/ELS.pdf
• National Cancer Institute clinical Trials and Translation Research Advisory Committee Progress in Small Cell Lung cancer Research Working Group available at: http://deainfo.nci.nih.gov/advisory/ctac/0716/4-SCLprogressReport_Jul%202016.pdf
• Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA). Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP. JAMA Oncol. 2016 Nov 17. doi: 10.1001/jamaoncol.2016.3834. [Epub ahead of print] PMID: 27892978
• Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study. Gomez DR, Blumenschein GR Jr, Lee JJ, Hernandez M, Ye R, Camidge DR, Doebele RC, Skoulidis F, Gaspar LE, Gibbons DL, Karam JA, Kavanagh BD, Tang C, Komaki R, Louie AV, Palma DA, Tsao AS, Sepesi B, William WN, Zhang J, Shi Q, Wang XS, Swisher SG, Heymach JV. Lancet Oncol. 2016 Dec;17(12):1672-1682. doi: 10.1016/S1470-2045(16)30532-0. PMID: 27789196
• Khalifa J, Amini A, Popat S, Gaspar LE, Faivre-Finn C; IASLC Advanced Radiation Technology Committee. Brain metastases from non-small cell lung cancer: radiation therapy in the era of targeted therapies. J Thorac Oncol. 2016 Jun 22. pii: S1556-0864(16)30519-6. doi: 10.1016/j.jtho.2016.06.002. [Epub ahead of print]
• The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases. Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP. Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):406-13. doi: 10.1016/j.ijrobp.2016.06.006.
• Neoadjuvant combination chemotherapy for unresectable stage III non-small cell lung cancer. Bunn PA Jr, Gaspar LE, Weyant MJ, Mitchell JD. Cancer. 2016 Mar 1;122(5):674-5. doi: 10.1002/cncr.29797. No abstract available. PMID: 26700372
• Combined-Modality Therapy With Radiation and Chemotherapy for Elderly Patients With Glioblastoma in the Temozolomide Era: A National Cancer Database Analysis. Rusthoven CG, Koshy M, Sher DJ, Ney DE, Gaspar LE, Jones BL, Karam SD, Amini A, Ormond DR, Youssef AS, Kavanagh BD. JAMA Neurol. 2016 Jul 1;73(7):821-8. doi: 10.1001/jamaneurol.2016.0839. PMID: 27214765
• Radiotherapeutic Management of Non-Small Cell Lung Cancer in the Minimal Resource Setting. Rodin D, Grover S, Xu MJ, Hanna TP, Olson R, Schreiner LJ, Munshi A, Mornex F, Palma D, Gaspar LE; International Association for the Study of Lung Cancer Advanced Radiation Technology Committee.. J Thorac Oncol. 2016 Jan;11(1):21-9. doi: 10.1016/j.jtho.2015.09.008. Review. PMID: 26762736
• Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY. Response assessment criteria for brain metastases: proposal from the RANO group. Lancet Oncol. 2015 Jun;16(6):e270-8. PubMed PMID: 26065612
• Carlson JA, Reddy K, Gaspar LE, Ney D, Kavanagh BD, Damek D, Lillehei K, Chen C. Hypofractionated-intensity modulated radiotherapy (hypo-IMRT) and temozolomide (TMZ) with or without bevacizumab (BEV) for newly diagnosed glioblastoma multiforme (GBM): a comparison of two prospective phase II trials. J Neurooncol. 2015 Jun;123(2):251-7. PubMed PMID: 25920710
• Brennan D, Schubert L, Diot Q, Castillo R, Castillo E, Guerrero T, Martel MK, Linderman D, Gaspar LE, Miften M, Kavanagh BD, Vinogradskiy Y. Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data. Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):423-9. PubMed PMID: 25817531
• Wozniak AJ, Moon J, Thomas CR Jr, Kelly K, Mack PC, Gaspar LE, Raben D, Fitzgerald TJ, Pandya KJ, Gandara DR. A Pilot Trial of Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Docetaxel and the Combination of Bevacizumab (NSC-704865) in Patients With Inoperable Locally Advanced Stage III Non-Small-Cell Lung Cancer: SWOG S0533. Clin Lung Cancer. 2015 Sep;16(5):340-7. PubMed PMID: 25703100
• Ney DE, Carlson JA, Damek DM, Gaspar LE, Kavanagh BD, Kleinschmidt-DeMasters BK, Waziri AE, Lillehei KO, Reddy K, Chen C. Phase II trial of hypofractionated intensity-modulated radiation therapy combined with temozolomide and bevacizumab for patients with newly diagnosed glioblastoma. J Neurooncol. 2015 Mar;122(1):135-43. PubMed PMID: 25524817
• Bunn, Jr. PA., Gaspar LE, Weyant M, Mitchell JD. Neoadjuvant combination chemotherapy for unresectable stage III NSCLC. (GASTO 1001) (CNCR-15-2173). Cancer.
• Gaspar LE. Results of RTOG 0617 reconsidered – No benefit of high-vs standard-dose radiotherapy or addition of cetuximab to chemoradiotherapy in stage IIIA or IIIB NSCLC. The ASCO Post, April 2015; 6 (6).

Professional Memberships

• American Society of Clinical Oncology (ASCO), Member
• Society for Neuro-Oncology, Member
• American Society for Radiation Oncology (ASTRO), Member, Prior Secretary/Treasurer
• International Society for the Study of Lung Cancer (IASLC), Board Member
• National Cancer Institute (NCI) Thoracic Malignancy Steering Committee, Co-Chair

Practice Locations

• University of Colorado Hospital
• Denver Health Medical Center
• Veterans Affairs Medical Center

• University of Colorado Cancer Center

Specialty Information

• Radiation Oncology, Board Certification

• Brain and Nervous System
• Brain and Nervous System - Brain Tumors
• Cancers - Lung Cancer
• Cancers - Radiation Therapy
• Cancers - Brain Cancer
• Cancers - Thoracic (Tracheal, Esophageal)
• Cancers