Thomas Morrison, PhD

Publications

• Frieman, M.B., Chen, J., Morrison, T.E., Whitmore, A., Funkhouser, W., Ward, J.M., Lamirande, E., Roberts, A., Heise, M., Subbarao, K., and Baric, R.S. 2010. SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II, and III interferon receptor independent mechanism. PLoS Pathog. 6(4), e1000849.
• Morrison, T.E.*, Oko, L., Montgomery, S.A., Whitmore, A.C., Lotstein, A.R., Gunn, B.M., Elmore, S.A., and Heise, M.T. 2011. A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence. American Journal of Pathology 178, 32-40. * corresonding author
• Jupille, H.J., Oko, L., Stoermer, K.A., Heise, M.T., Mahalingam, S., Gunn, B.M., and Morrison, T.E. 2010. Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model. Virology 410, 216-27.
• Stoermer, K.A. and Morrison, T.E. 2011 Complement and viral pathogenesis. Virology 411, 362-73.
• O'Brien, K.B., Morrison, T.E., Dundore, D.Y., Heise, M.T., Schultz-Cherry, S. 2011. A protective role for complement C3 protein during pandemic 2009 H1Ni and H5N1 influenza virus infection. PLoS One 6(3), e17377.
• Gunn, B.G.*, Morrison, T.E.*, Whitmore, A.C., Blevins, L.K., Hueston, L., Fraser, R.J., Herrero, L., Mahalingam, S., and Heise, M.T. Mannose binding lectin is required for alphavirus-induced arthritis and myositis. PLoS Pathogens, manuscript in press. * these authors contributed equally
• Gunn, B.G.*, Morrison, T.E.*, Whitmore, A.C., Blevins, L.K., Hueston, L., Fraser, R.J., Herrero, L., Mahalingam, S., and Heise, M.T. 2012. Mannose binding lectin is required for alphavirus-induced arthritis and myositis. PLoS Pathogens 8(3), e1002586. * these authors contributed equally
• Stoermer, K.A., Burrack, A., Oko, L., Montgomery, S.A., Borst, L.B., Gill, R.G., and Morrison, T.E. 2012. Genetic ablation of arginase 1 in macrophages and neutrophils enhances clearance of an arthritogenic alphavirus. Journal of Immunology 189, 4047-4059.
• Dickson, A.M., Anderson, J.R., Barnhart, M.D., Sokoloski, K.J., Oko, L., Opyrchal, M., Glalnis, E., Wilusz, C.J., Morrison, T.E., and Wilusz, J. 2012. Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm. Journal of Biological Chemistry 287, 36229-36238.
• Jupille, H.J., Medina-Rivera, M., Hawman, D.W., Oko, L., and Morrison, T.E. 2013. A tyrosine to histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts. J. Virol., manuscript under review.
• Jupille HJ, Medina-Rivera M, Hawman DW, Oko L, Morrison TE. A tyrosine-to-histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts. J Virol. 2013 May;87(10):5970-84. PubMed PMID: 23514884
• Hawman DW, Stoermer KA, Montgomery SA, Pal P, Oko L, Diamond MS, Morrison TE. Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response. J Virol. 2013 Dec;87(24):13878-88. PubMed PMID: 24131709
• Silva LA, Khomandiak S, Ashbrook AW, Weller R, Heise MT, Morrison TE, Dermody TS. A single-amino-Acid polymorphism in chikungunya virus e2 glycoprotein influences glycosaminoglycan utilization. J Virol. 2014 Mar;88(5):2385-97. PubMed PMID: 24371059
• Burrack KA, Hawman DW, Jupille HJ, Oko L, Minor M, Shives KD, Gunn BM, Long KM, Morrison TE. Attenuating mutations in nsP1 reveal tissue specific mechanisms for control of Ross River virus infection. J Virol. 2014 Jan 15. [Epub ahead of print] PubMed PMID: 24429363
• Burrack KS, Morrison TE. The role of myeloid cell activation and arginine metabolism in the pathogenesis of virus-induced diseases. Front Immunol. 2014;5:428. PubMed PMID: 25250029
• Ashbrook AW, Burrack KS, Silva LA, Montgomery SA, Heise MT, Morrison TE, Dermody TS. Residue 82 of the Chikungunya virus E2 attachment protein modulates viral dissemination and arthritis in mice. J Virol. 2014 Nov;88(21):12180-92. PubMed PMID: 25142598
• Morrison TE. Reemergence of chikungunya virus. J Virol. 2014 Oct;88(20):11644-7. PubMed PMID: 25078691
• Monin L, Griffiths KL, Lam WY, Gopal R, Kang DD, Ahmed M, Rajamanickam A, Cruz-Lagunas A, Zúñiga J, Babu S, Kolls JK, Mitreva M, Rosa BA, Ramos-Payan R, Morrison TE, Murray PJ, Rangel-Moreno J, Pearce EJ, Khader SA. Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis. J Clin Invest. 2015 Dec 1;125(12):4699-713. PubMed PMID: 26571397
• Banda NK, Mehta G, Kjaer TR, Takahashi M, Schaack J, Morrison TE, Thiel S, Arend WP, Holers VM. Essential role for the lectin pathway in collagen antibody-induced arthritis revealed through use of adenovirus programming complement inhibitor MAp44 expression. J Immunol. 2014 Sep 1;193(5):2455-68. PubMed PMID: 25070856
• Burrack KS, Tan JJ, McCarthy MK, Her Z, Berger JN, Ng LF, Morrison TE. Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells. PLoS Pathog. 2015 Oct;11(10):e1005191. PubMed PMID: 26436766
• Pal P, Fox JM, Hawman DW, Huang YJ, Messaoudi I, Kreklywich C, Denton M, Legasse AW, Smith PP, Johnson S, Axthelm MK, Vanlandingham DL, Streblow DN, Higgs S, Morrison TE, Diamond MS. Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes. J Virol. 2014 Aug;88(15):8213-26. PubMed PMID: 24829346
• McSweegan E, Weaver SC, Lecuit M, Frieman M, Morrison TE, Hrynkow S. The Global Virus Network: Challenging chikungunya. Antiviral Res. 2015 Aug;120:147-52. PubMed PMID: 26071007
• Stoermer Burrack KA, Hawman DW, Jupille HJ, Oko L, Minor M, Shives KD, Gunn BM, Long KM, Morrison TE. Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection. J Virol. 2014 Apr;88(7):3719-32. PubMed PMID: 24429363
• Sokoloski KJ, Haist KC, Morrison TE, Mukhopadhyay S, Hardy RW. Noncapped Alphavirus Genomic RNAs and Their Role during Infection. J Virol. 2015 Jun;89(11):6080-92. PubMed PMID: 25833042
• Halemano K, Barrett BS, Heilman KJ, Morrison TE, Santiago ML. Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response. J Virol. 2015 Apr;89(7):4011-4. PubMed PMID: 25589647
• Burrack KS, Montgomery SA, Homann D, Morrison TE. CD8 T cells control Ross River virus infection in musculoskeletal tissues of infected mice. J Immunol. 2015 Jan 15;194(2):678-89. PubMed PMID: 25488988
• Silva LA, Khomandiak S, Ashbrook AW, Weller R, Heise MT, Morrison TE, Dermody TS. A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization. J Virol. 2014 Mar;88(5):2385-97. PubMed PMID: 24371059
• Hawman, D.W. and Morrison, T.E. 2016. Chikungunya Pathogenesis. In: Okeoma, C. (ed.): Chikungunya virus. Springer, New York.
• Haist KC, Burrack KS, Davenport BJ, Morrison TE. Inflammatory monocytes mediate control of acute alphavirus infection in mice. PLoS Pathog. 2017 Dec;13(12):e1006748. PubMed PMID: 29244871
• Carpentier KS, Morrison TE. Innate immune control of alphavirus infection. Curr Opin Virol. 2017 Nov 22;28:53-60. [Epub ahead of print] PubMed PMID: 29175515
• Haese NN, Broeckel RM, Hawman DW, Heise MT, Morrison TE, Streblow DN. Animal Models of Chikungunya Virus Infection and Disease. J Infect Dis. 2016 Dec 15;214(suppl 5):S482-S487. PubMed PMID: 27920178
• Hawman DW, Carpentier KS, Fox JM, May NA, Sanders W, Montgomery SA, Moorman NJ, Diamond MS, Morrison TE. MUTATIONS IN THE E2 GLYCOPROTEIN AND THE 3' UNTRANSLATED REGION ENHANCE CHIKUNGUNYA VIRUS VIRULENCE IN MICE. J Virol. 2017 Jul 26. [Epub ahead of print] PubMed PMID: 28747508
• Sokoloski KJ, Nease LM, May NA, Gebhart NN, Jones CE, Morrison TE, Hardy RW. Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants. PLoS Pathog. 2017 Jun;13(6):e1006473. PubMed PMID: 28662211
• Shives KD, Massey AR, May NA, Morrison TE, Beckham JD. 4EBP-Dependent Signaling Supports West Nile Virus Growth and Protein Expression. Viruses. 2016 Oct 18;8(10). PubMed PMID: 27763553
• Hawman DW, Fox JM, Ashbrook AW, May NA, Schroeder KM, Torres RM, Crowe JE Jr, Dermody TS, Diamond MS, Morrison TE. Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence. Cell Rep. 2016 Aug 2;16(5):1326-38. PubMed PMID: 27452455
• Ashbrook AW, Lentscher AJ, Zamora PF, Silva LA, May NA, Bauer JA, Morrison TE, Dermody TS. Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection. MBio. 2016 May 24;7(3). PubMed PMID: 27222471
• McCarthy MK, Morrison TE. Chronic chikungunya virus musculoskeletal disease: what are the underlying mechanisms?. Future Microbiol. 2016;11(3):331-4. PubMed PMID: 26939523
• McCarthy MK, Morrison TE. Persistent RNA virus infections: do PAMPS drive chronic disease?. Curr Opin Virol. 2017 Apr;23:8-15. PubMed PMID: 28214732
• Morrison TE, Diamond MS. Animal Models of Zika Virus Infection, Pathogenesis, and Immunity. J Virol. 2017 Apr 15;91(8). PubMed PMID: 28148798
• Davenport BJ, Martin CG, Beverley SM, Orlicky DJ, Vazquez-Torres A, Morrison TE. SODB1 is essential for Leishmania major infection of macrophages and pathogenesis in mice. PLoS Negl Trop Dis. 2018 Oct;12(10):e0006921. PubMed PMID: 30372439
• Gralinski LE, Sheahan TP, Morrison TE, Menachery VD, Jensen K, Leist SR, Whitmore A, Heise MT, Baric RS. Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis. MBio. 2018 Oct 9;9(5). PubMed PMID: 30301856
• McCarthy MK, Morrison TE. Blocking the Exit: CHIKV Neutralizing Antibodies Nip Viral Egress in the Bud. Cell Host Microbe. 2018 Sep 12;24(3):328-330. PubMed PMID: 30212644
• Lentscher AJ, McCarthy MK, May NA, Davenport BJ, Montgomery SA, Raghunathan K, McAllister N, Silva LA, Morrison TE, Dermody TS. Chikungunya virus replication in skeletal muscle cells is required for disease development. J Clin Invest. 2019 Dec 3. [Epub ahead of print] PubMed PMID: 31794434
• Lucas ED, Finlon JM, Burchill MA, McCarthy MK, Morrison TE, Colpitts TM, Tamburini BAJ. Type 1 IFN and PD-L1 Coordinate Lymphatic Endothelial Cell Expansion and Contraction during an Inflammatory Immune Response. J Immunol. 2018 Sep 15;201(6):1735-1747. PubMed PMID: 30045970
• Broeckel RM, Haese N, Ando T, Dmitriev I, Kreklywich CN, Powers J, Denton M, Smith P, Morrison TE, Heise M, DeFilippis V, Messaoudi I, Curiel DT, Streblow DN. Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease. Front Immunol. 2019;10:2563. PubMed PMID: 31736977
• Decker CJ, Steiner HR, Hoon-Hanks LL, Morrison JH, Haist KC, Stabell AC, Poeschla EM, Morrison TE, Stenglein MD, Sawyer SL, Parker R. dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA. Viruses. 2019 Oct 14;11(10). PubMed PMID: 31615058
• Carpentier KS, Davenport BJ, Haist KC, McCarthy MK, May NA, Robison A, Ruckert C, Ebel GD, Morrison TE. Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses. Elife. 2019 Oct 9;8. PubMed PMID: 31596239
• McCarthy MK, Davenport BJ, Reynoso GV, Lucas ED, May NA, Elmore SA, Tamburini BA, Hickman HD, Morrison TE. Chikungunya virus impairs draining lymph node function by inhibiting HEV-mediated lymphocyte recruitment. JCI Insight. 2018 Jul 12;3(13). [Epub ahead of print] PubMed PMID: 29997290
• Gunn BM, Jones JE, Shabman RS, Whitmore AC, Sarkar S, Blevins LK, Morrison TE, Heise MT. Ross River virus envelope glycans contribute to disease through activation of the host complement system. Virology. 2018 Feb;515:250-260. PubMed PMID: 29324290
• Carpentier KS, Morrison TE. Innate immune control of alphavirus infection. Curr Opin Virol. 2018 Feb;28:53-60. PubMed PMID: 29175515
• Gall B, Pryke K, Abraham J, Mizuno N, Botto S, Sali TM, Broeckel R, Haese N, Nilsen A, Placzek A, Morrison T, Heise M, Streblow D, DeFilippis V. Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway. J Virol. 2018 Mar 15;92(6). PubMed PMID: 29263267
• Hong JP, McCarthy MK, Davenport BJ, Morrison TE, Diamond MS. Clearance of Chikungunya Virus Infection in Lymphoid Tissues Is Promoted by Treatment with an Agonistic Anti-CD137 Antibody. J Virol. 2019 Dec 15;93(24). PubMed PMID: 31578287
• Nguyen TH, Haese NN, Madadi N, Sarkar S, Bonin K, Streblow CE, Taft-Benz S, Tower NA, Rasmussen L, Bostwick R, Augelli-Szafran CE, Suto MJ, Morrison TE, DeFilippis V, Heise MT, Streblow DN, Pathak AK. Studies on Dibenzylamines as Inhibitors of Venezuelan Equine Encephalitis Virus. ACS Infect Dis. 2019 Dec 13;5(12):2014-2028. PubMed PMID: 31257853
• Broeckel R, Sarkar S, May NA, Totonchy J, Kreklywich CN, Smith P, Graves L, DeFilippis VR, Heise MT, Morrison TE, Moorman N, Streblow DN. Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs. Antimicrob Agents Chemother. 2019 Apr;63(4). PubMed PMID: 30917980
• Amaral JK, Taylor PC, Teixeira MM, Morrison TET, Schoen RT. The Clinical Features, Pathogenesis and Methotrexate Therapy of Chronic Chikungunya Arthritis. Viruses. 2019 Mar 22;11(3). PubMed PMID: 30909365
• McCarthy MK, Davenport BJJ, Morrison TE. Chronic Chikungunya Virus Disease. Curr Top Microbiol Immunol. 2019 Jan 18. [Epub ahead of print] PubMed PMID: 30656438
• Wang G, Gaikwad H, McCarthy MK, Gonzalez-Juarrero M, Li Y, Armstrong M, Reisdorph N, Morrison TE, Simberg D. Lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro . Precis Nanomed. 2021 Apr 17;4(1):724-737. PubMed PMID: 34676370
• Carpentier KS, Sheridan RM, Lucas CJ, Davenport BJ, Li FS, Lucas ED, McCarthy MK, Reynoso GV, May NA, Tamburini BAJ, Hesselberth JR, Hickman HD, Morrison TE. MARCO( ) lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination. EMBO J. 2021 Nov 15;40(22):e108966. PubMed PMID: 34618370
• Huey L, Andersen G, Merkel PA, Morrison TE, McCarthy M, DomBourian MG, Annen K, Dawson ED, Rowlen KL, Knight V. Evaluation of a multiplexed coronavirus antigen array for detection of SARS-CoV-2 specific IgG in COVID-19 convalescent plasma. J Immunol Methods. 2021 Oct;497:113104. PubMed PMID: 34303688
• Prow NA, Liu L, McCarthy MK, Walters K, Kalkeri R, Geiger J, Koide F, Cooper TH, Eldi P, Nakayama E, Diener KR, Howley PM, Hayball JD, Morrison TE, Suhrbier A. The vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates. NPJ Vaccines. 2020;5:44. PubMed PMID: 32550013
• Haese NN, May NA, Taft-Benz S, Moukha-Chafiq O, Madadi N, Zhang S, Karyakarte SD, Rodzinak KJ, Nguyen TH, Denton M, Streblow AD, Towers NA, Rasmussen L, Bostwick RJ, Maddry JA, Ananthan S, Augelli-Szafran CE, Suto MJ, Sanders W, Moorman N, DeFilippis V, Heise MT, Pathak AK, Streblow DN, Morrison TE. Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0024421. PubMed PMID: 34152810
• Powell LA, Fox JM, Kose N, Kim AS, Majedi M, Bombardi R, Carnahan RH, Slaughter JC, Morrison TE, Diamond MS, Crowe JE Jr. Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease. PLoS Pathog. 2020 May;16(5):e1008517. PubMed PMID: 32365139
• Noll KE, Whitmore AC, West A, McCarthy MK, Morrison CR, Plante KS, Hampton BK, Kollmus H, Pilzner C, Leist SR, Gralinski LE, Menachery VD, Schäfer A, Miller D, Shaw G, Mooney M, McWeeney S, Pardo-Manuel de Villena F, Schughart K, Morrison TE, Baric RS, Ferris MT, Heise MT. Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross. Cell Rep. 2020 Apr 28;31(4):107587. PubMed PMID: 32348764
• Kuhn KA, Morrison TE. Introduction: Evolution of inflammatory arthritis from innate to adaptive immune mechanisms. Immunol Rev. 2020 Mar;294(1):5-8. PubMed PMID: 32103544
• Davenport BJ, Bullock C, McCarthy MK, Hawman DW, Murphy KM, Kedl RM, Diamond MS, Morrison TE. Chikungunya Virus Evades Antiviral CD8( ) T Cell Responses To Establish Persistent Infection in Joint-Associated Tissues. J Virol. 2020 Apr 16;94(9). PubMed PMID: 32102875
• Stenmark KR, Frid MG, Gerasimovskaya E, Zhang H, McCarthy MK, Thurman JM, Morrison TE. Mechanisms of SARS-CoV-2-induced lung vascular disease: potential role of complement. Pulm Circ. 2021 Apr-Jun;11(2):20458940211015799. PubMed PMID: 34046161
• Davenport BJ, Morrison TE, Kedl RM, Klarquist J. Conserved and Novel Mouse CD8 T Cell Epitopes within SARS-CoV-2 Spike Receptor Binding Domain Protein Identified following Subunit Vaccination. J Immunol. 2021 Jun 1;206(11):2503-2507. PubMed PMID: 33972373
• Ahmed SK, Haese NN, Cowan JT, Pathak V, Moukha-Chafiq O, Smith VJ, Rodzinak KJ, Ahmad F, Zhang S, Bonin KM, Streblow AD, Streblow CE, Kreklywich CN, Morrison C, Sarkar S, Moorman N, Sander W, Allen R, DeFilippis V, Tekwani BL, Wu M, Hirsch AJ, Smith JL, Tower NA, Rasmussen L, Bostwick R, Maddry JA, Ananthan S, Gerdes JM, Augelli-Szafran CE, Suto MJ, Morrison TE, Heise MT, Streblow DN, Pathak AK. Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors. J Med Chem. 2021 Apr 22;64(8):4762-4786. PubMed PMID: 33835811
• McCarthy MK, Reynoso GV, Winkler ES, Mack M, Diamond MS, Hickman HD, Morrison TE. MyD88-dependent influx of monocytes and neutrophils impairs lymph node B cell responses to chikungunya virus infection via Irf5, Nos2 and Nox2. PLoS Pathog. 2020 Jan;16(1):e1008292. PubMed PMID: 31999809
• Lentscher AJ, McCarthy MK, May NA, Davenport BJ, Montgomery SA, Raghunathan K, McAllister N, Silva LA, Morrison TE, Dermody TS. Chikungunya virus replication in skeletal muscle cells is required for disease development. J Clin Invest. 2020 Mar 2;130(3):1466-1478. PubMed PMID: 31794434
• Schultz JS, McCarthy MK, Rester C, Sabourin KR, Annen K, DomBourian M, Eisenmesser E, Frazer-Abel A, Knight V, Jaenisch T, Morrison TE, Rochford R, Kedl RM. Development and Validation of a Multiplex Microsphere Immunoassay Using Dried Blood Spots for SARS-CoV-2 Seroprevalence: Application in First Responders in Colorado, USA. J Clin Microbiol. 2021 May 19;59(6). PubMed PMID: 33795412
• Powers JM, Haese NN, Denton M, Ando T, Kreklywich C, Bonin K, Streblow CE, Kreklywich N, Smith P, Broeckel R, DeFilippis V, Morrison TE, Heise MT, Streblow DN. Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses. PLoS Negl Trop Dis. 2021 Apr;15(4):e0009308. PubMed PMID: 33793555
• Taylor SC, Hurst B, Charlton CL, Bailey A, Kanji JN, McCarthy MK, Morrison TE, Huey L, Annen K, DomBourian MG, Knight V. A New SARS-CoV-2 Dual-Purpose Serology Test: Highly Accurate Infection Tracing and Neutralizing Antibody Response Detection. J Clin Microbiol. 2021 Mar 19;59(4). PubMed PMID: 33500361
• Annen K, Morrison TE, DomBourian MG, McCarthy MK, Huey L, Merkel PA, Andersen G, Schwartz E, Knight V. Presence and short-term persistence of SARS-CoV-2 neutralizing antibodies in COVID-19 convalescent plasma donors. Transfusion. 2021 Apr;61(4):1148-1159. PubMed PMID: 33452828
• Haist KC, Carpentier KS, Davenport BJ, Morrison TE. Plasmacytoid Dendritic Cells Mediate Control of Ross River Virus Infection via a Type I Interferon-Dependent, MAVS-Independent Mechanism. J Virol. 2021 Feb 24;95(6). PubMed PMID: 33361425
• Sabourin KR, Schultz J, Romero J, Lamb MM, Larremore D, Morrison TE, Frazer-Abel A, Zimmer S, Kedl RM, Jaenisch T, Rochford R. Risk Factors of SARS-CoV-2 Antibodies in Arapahoe County First Responders-The COVID-19 Arapahoe SErosurveillance Study (CASES) Project. J Occup Environ Med. 2021 Mar 1;63(3):191-198. PubMed PMID: 33298759
• Lucas CJ, Morrison TE. Animal models of alphavirus infection and human disease. Adv Virus Res. 2022;113:25-88. PubMed PMID: 36307168
• Kim JS, Liu L, Davenport B, Kant S, Morrison TE, Vazquez-Torres A. Oxidative stress activates transcription of Salmonella pathogenicity island-2 genes in macrophages. J Biol Chem. 2022 Jul;298(7):102130. PubMed PMID: 35714768
• Windsor WJ, Roell Y, Tucker H, Cheng CA, Suliman S, Peek LJ, Pestano GA, Lee WT, Zeichhardt H, Lamb MM, Kammel M, Wang H, Kedl R, Rester C, Morrison TE, Davenport BJ, Carson K, Yates J, Howard K, Kulas K, Walt DR, Dafni A, Taylor D, Chu M. Harmonization of Multiple SARS-CoV-2 Reference Materials Using the WHO IS (NIBSC 20/136): Results and Implications. Front Microbiol. 2022;13:893801. PubMed PMID: 35707164
• Davenport BJ, Catala A, Weston SM, Johnson RM, Ardanuy J, Hammond HL, Dillen C, Frieman MB, Catalano CE, Morrison TE. Phage-like particle vaccines are highly immunogenic and protect against pathogenic coronavirus infection and disease. NPJ Vaccines. 2022 May 26;7(1):57. PubMed PMID: 35618725
• Ander SE, Li FS, Carpentier KS, Morrison TE. Innate immune surveillance of the circulation: A review on the removal of circulating virions from the bloodstream. PLoS Pathog. 2022 May;18(5):e1010474. PubMed PMID: 35511797
• Lucas CJ, Davenport BJ, Carpentier KS, Tinega AN, Morrison TE. Two Conserved Phenylalanine Residues in the E1 Fusion Loop of Alphaviruses Are Essential for Viral Infectivity. J Virol. 2022 May 11;96(9):e0006422. PubMed PMID: 35416719
• Windsor WJ, Knight V, Merkel PA, Lamb MM, Tucker HR, Carson K, Howard KM, Yates JL, Santiago ML, McCarthy MK, Morrison TE, Kedl RM, Frazer-Abel A, Guo K, Andersen G, Huey L, Barrett BS, Colón-Franco JM, Lee WT, Chu MC. COVID-19 Serology Control Panel Using the Dried-Tube Specimen Method. Am J Trop Med Hyg. 2022 Jan 7;106(2):562-565. PubMed PMID: 34996045
• Ware BC, Parks MG, Morrison TE. Chikungunya virus infection disrupts MHC-I antigen presentation via nonstructural protein 2. bioRxiv. 2023 Nov 4. PubMed PMID: 37961400
• Lucas CJ, Sheridan RM, Reynoso GV, Davenport BJ, McCarthy MK, Martin A, Hesselberth JR, Hickman HD, Tamburini BAJ, Morrison TE. Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO. bioRxiv. 2023 Oct 13. PubMed PMID: 37873393
• Ander SE, Parks MG, Davenport BJ, Li FS, Bosco-Lauth A, Carpentier KS, Sun C, Lucas CJ, Klimstra WB, Ebel GD, Morrison TE. Phagocyte-expressed glycosaminoglycans promote capture of alphaviruses from the blood circulation in a host species-specific manner. bioRxiv. 2023 Aug 9. PubMed PMID: 37609165
• Yin P, Davenport BJ, Wan JJ, Kim AS, Diamond MS, Ware BC, Tong K, Couderc T, Lecuit M, Lai JR, Morrison TE, Kielian M. Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo. Nat Microbiol. 2023 Sep;8(9):1653-1667. PubMed PMID: 37591996
• Kedl RM, Hsieh EWY, Morrison TE, Samayoa-Reyes G, Flaherty S, Jackson CL, Rochford R. Evidence for Aerosol Transfer of SARS-CoV-2-Specific Humoral Immunity. Immunohorizons. 2023 May 1;7(5):307-309. PubMed PMID: 37159005
• Li FS, Carpentier KS, Hawman DW, Lucas CJ, Ander SE, Feldmann H, Morrison TE. Species-specific MARCO-alphavirus interactions dictate chikungunya virus viremia. Cell Rep. 2023 May 30;42(5):112418. PubMed PMID: 37083332
• Zhang H, Gerasimovskaya E, McCarthy MK, May NA, Prasad RR, Riddle S, McKeon BA, Kumar S, Li M, Hu CJ, Frid MG, Morrison TE, Stenmark KR. Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection. Am J Respir Cell Mol Biol. 2023 Aug;69(2):210-219. PubMed PMID: 37071849
• Garzan A, Ahmed SK, Haese NN, Sulgey G, Medica S, Smith JL, Zhang S, Ahmad F, Karyakarte S, Rasmussen L, DeFilippis V, Tekwani B, Bostwick R, Suto MJ, Hirsch AJ, Morrison TE, Heise MT, Augelli-Szafran CE, Streblow DN, Pathak AK, Moukha-Chafiq O. 4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses. J Med Chem. 2024 Dec 2. [Epub ahead of print] PubMed PMID: 39621435
• Catala A, Davenport BJ, Morrison TE, Catalano CE. Second-Generation Phage Lambda Platform Employing SARS-CoV-2 Fusion Proteins as a Vaccine Candidate. Vaccines (Basel). 2024 Oct 22;12(11). PubMed PMID: 39591104
• Bullock CB, Wang L, Ware BC, Wagoner N, Ohara RA, Liu T-T, Desai P, Peters B, Murphy KM, Handley SA, Morrison TE, Diamond MS. Type I interferon signaling in dendritic cells limits direct antigen presentation and CD8( ) T cell responses against an arthritogenic alphavirus. mBio. 2024 Nov 13;:e0293024. [Epub ahead of print] PubMed PMID: 39535221
• Hu P, Xiao H, Alba MA, Atkins HM, Gou S, Hu Y, Gomez JC, Jania CM, Martin JR, Morrison TE, Tilley SL, Heise MT, Doerschuk CM, Falk RJ, Jennette JC. Myeloperoxidase-ANCA IgG induces different forms of small vessel vasculitis based on type of synergistic immune stimuli. Kidney Int. 2024 Nov;106(5):870-886. PubMed PMID: 39216658
• Ander SE, Carpentier KS, Sanders W, Lucas CJ, Jolly AJ, Johnson CN, Hawman DW, Heise MT, Moorman NJ, Morrison TE. A 44-Nucleotide Region in the Chikungunya Virus 3' UTR Dictates Viral Fitness in Disparate Host Cells. Viruses. 2024 May 28;16(6). PubMed PMID: 38932154
• Yin P, May NA, Lello LS, Fayed A, Parks MG, Drobish AM, Wang S, Andrews M, Sticher Z, Kolykhalov AA, Natchus MG, Painter GR, Merits A, Kielian M, Morrison TE. 4'-Fluorouridine inhibits alphavirus replication and infection in vitro and in vivo. mBio. 2024 Jun 12;15(6):e0042024. PubMed PMID: 38700353
• Chia SB, Johnson BJ, Hu J, Vermeulen R, Chadeau-Hyam M, Guntoro F, Montgomery H, Boorgula MP, Sreekanth V, Goodspeed A, Davenport B, Pereira FV, Zaberezhnyy V, Schleicher WE, Gao D, Cadar AN, Papanicolaou M, Beheshti A, Baylin SB, Costello J, Bartley JM, Morrison TE, Aguirre-Ghiso JA, Rincon M, DeGregori J. Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungs. Res Sq. 2024 Apr 5. PubMed PMID: 38645169
• Sheridan RM, Doan TA, Lucas C, Forward TS, Uecker-Martin A, Morrison TE, Hesselberth JR, Tamburini BAJ. A specific and portable gene expression program underlies antigen archiving by lymphatic endothelial cells. bioRxiv. 2024 Apr 2. PubMed PMID: 38617225
• Ander SE, Parks MG, Davenport BJ, Li FS, Bosco-Lauth A, Carpentier KS, Sun C, Lucas CJ, Klimstra WB, Ebel GD, Morrison TE. Phagocyte-expressed glycosaminoglycans promote capture of alphaviruses from the blood circulation in a host species-specific manner. PNAS Nexus. 2024 Apr;3(4):pgae119. PubMed PMID: 38560529
• Doan TA, Forward TS, Schafer JB, Lucas ED, Fleming I, Uecker-Martin A, Ayala E, Guthmiller JJ, Hesselberth JR, Morrison TE, Tamburini BAJ. Immunization-induced antigen archiving enhances local memory CD8 T cell responses following an unrelated viral infection. NPJ Vaccines. 2024 Mar 21;9(1):66. PubMed PMID: 38514656
• Ware BC, Parks MG, da Silva MOL, Morrison TE. Chikungunya virus infection disrupts MHC-I antigen presentation via nonstructural protein 2. PLoS Pathog. 2024 Mar;20(3):e1011794. PubMed PMID: 38483968
• Holmes AC, Lucas CJ, Brisse ME, Ware BC, Hickman HD, Morrison TE, Diamond MS. Ly6C( ) monocytes in the skin promote systemic alphavirus dissemination. Cell Rep. 2024 Mar 26;43(3):113876. PubMed PMID: 38446669
• Kim JS, Liu L, Kant S, Orlicky DJ, Uppalapati S, Margolis A, Davenport BJ, Morrison TE, Matsuda J, McClelland M, Jones-Carson J, Vazquez-Torres A. Anaerobic respiration of host-derived methionine sulfoxide protects intracellular Salmonella from the phagocyte NADPH oxidase. Cell Host Microbe. 2024 Mar 13;32(3):411-424.e10. PubMed PMID: 38307020
• Lucas CJ, Sheridan RM, Reynoso GV, Davenport BJ, McCarthy MK, Martin A, Hesselberth JR, Hickman HD, Tamburini BA, Morrison TE. Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO. JCI Insight. 2024 Jan 9;9(4). PubMed PMID: 38194268

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Specialty Information

Specialties

• Allergy and Immunology