Tatiana Kutateladze, PhD

Publications

• Zhang H, He J , Kutateladze AG, Sakai T, Sasaki T, Markadieu N, Erneux C, Prestwich GD 5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration. ChemBioChem 11:388-395 (2010)
• Garske AL, Oliver SS, Wagner EK, Musselman CA, LeRoy G, Garcia BA, Kutateladze AG, Denu JM Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination for posttranslational modifications. Nature Chem Biol (In Press) (2010)
• Roy S, Musselman CA, Kachirskaia I, Hayashi R, Glass KC, Nix JC, Gozani O, Appella E, Kutateladze TG Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J Mol Biol 398:489-496 (2010)
• Chang PY, Hom RA, Musselman CA, Zhu L, Kuo A, Gozani O, Kutateladze AG, Cleary ML Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL dependent gene transcription. J Mol Biol 400:137-144 (2010)
• Hom RA, Chang PY, Roy S, Musselman CA, Champagne KS, Selezneva AI, Gozani O, Ismagilov RF, Cleary ML, Kutateladze AG Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain. J Mol Biol 400:145-154 (2010)
• 4. West, L.E., Roy, S., Lachmi-Weiner, K., Hayashi, R., Shi, X., Appella, E., Kutateladze, T.G.* and Gozani, O.* The MBT repeats of L3MBTL1 link SET8 mediated p53 methylation at lysine 382 to target gene repression, J. Biol. Chem., 285, 37725-32 (2010). (* co-corresponding authors)
• 5. Kutateladze, T.G. Translation of the phosphoinositide code by PI effectors, Nature Chem. Biol., invited review, 6, 507-13 (2010).
• 14. Mansfield, R.E., Musselman, C.A., Kwan, A., Oliver, S.S., Garske, A.L., Davrazou, F., Denu, J.M., Kutateladze, T.G. and Mackay, J.P. The plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9, J. Biol. Chem., 286, 11779-91, (2011).
• 89. Allen, H.F., Wade, P.A., and Kutateladze, T.G. 2013. The NuRD architecture. Cell Mol Life Sci., 70, 3513-24.
• 90. Ali, M., Rincon-Arano, H., Zhao, W., Rothbart, S.B., Tong, Q., Parkhurst, S.M., Strahl, B.D., Deng, L-W., Groudine, M. and Kutateladze, T.G. 2013. Molecular basis for chromatin binding and regulation of MLL5, Proc. Natl. Acad. Sci. USA, 110, 11296-301
• 91. Gatchalian, J., Fütterer, A., Rothbart, S.B., Tong, Q., Rincon-Arano, H., de Diego, A.S., Groudine, M., Strahl, B.D., Martínez-A, C., van Wely, K.H.M and Kutateladze, T.G. 2013. Dido3 PHD modulates cell differentiation and division, Cell Rep., 4, 148-58.
• 92. Lalonde, M.E., Avvakumov, N., Glass, K.C., Joncas, F.-H., Saksouk, N., Holliday, M., Paquet, E., Yan, K., Tong, Q., Klein, B.J., Tan, S., Yang, X.J., Kutateladze T.G. and Côté, J. 2013. Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity. Genes Dev., 27, 2009-24.
• 93. Musselman, C.A., Gibson, M.D., Hartwick, E.W., North, J.A., Gatchalian, J., Poirier, M.G. and Kutateladze, T.G. 2013. Binding of PHF1 Tudor to H3K36me3 enhances nucleosome accessibility. Nature Commun., 4, 2969.
• 94. Allen, H.F., Daze, K.D., Lai, A., Musselman, C.A., Sims, J.K., Wade, P.A., Hof, F. and Kutateladze, T.G. 2014. Inhibition of histone readers by supramolecular hosts, Biochem. J. in press.
• 15. He, J., Scott, J.L., Heroux, A., Roy, S., Lenoir, M., Overduin, M., Stahelin, R.V. and Kutateladze, T.G. Molecular basis of phosphatidylinositol 4-phosphate and ARF1 recognition by FAPP1 PH domain. J. Biol. Chem., online March 22 (2011).
• 95. Musselman, C.A., Khorasanizadeh, S. and Kutateladze, T.G. 2014. Towards understanding methyllysine readout, Biochim. Biophys. Acta, in press.
• 96. Klein, B.J., Lalonde, M.E., Côté, J., Yang, X.J. and Kutateladze, T.G. 2014. Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes, Epigenetics, 9, 186-93 (featured on cover).
• 97. Das, C., Roy, S., Namjoshi, S., Malarkey, C.S., Jones, D.N.M., Kutateladze, T.G., Churchill, M.E.A. and Tyler, J.K. 2014. Recognition of acetylated histone H3 lysine 56 and the histone chaperone ASF1 by the CBP bromodomain promotes acetylation of non chromatin-bound histones, Proc. Natl. Acad. Sci. USA, accepted.
• 98. Alpatov, R., Lesch, B.J., Nakamoto-Kinoshita, M., Blanco, A., Chen, S., Stützer, A., Armache, K.J., Simon, M.D., Ali, M., Murn, J., Prisic, S., Kutateladze, T.G., Vakoc, C.R., Kingston, R.E., Fischle, W., Warren, S.T., Page, D.C., and Shi, Y. A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response, Cell, in press
• 99. Ali, M., Hom, R.A., Blakeslee, W., Ikenouye, L. and Kutateladze, T.G. 2014. Diverse functions of PHD fingers of the MLL/KMT2 subfamily, Biochim. Biophys. Acta, 1843, 366-71.
• 100. Klein, B.J., Piao, L., Xi, Y., Rincon-Arano, H., Rothbart, S.B., Larson, C., Wen, H., Zheng. X., Cortazar, M., Peña, P.V., Mangan, A., Bentley, D.L., Strahl, B.D., Groudine, M., Li, W., Shi, X., and Kutateladze, T.G. 2014. KDM5B demethylase binds to its histone substrate and product through distinct modules, Cell Rep., 6, 325-35.