Kurt Beam, PhD
Distinguished Professor, Physiology & Biophysics

Publications

  • Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister RA, Hopkins PM, Beam KG, Allen PD, Pessah IN. Putative malignant hyperthermia mutation Ca(V)1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance. J Biol Chem. 2023 Aug;299(8):104992. PubMed PMID: 37392848
  • Peters CH, Rickert C, Morotti S, Grandi E, Aronow KA, Beam KG, Proenza C. The funny current If is essential for the fight-or-flight response in cardiac pacemaker cells. J Gen Physiol. 2022 Dec 5;154(12). PubMed PMID: 36305844
  • Dayal A, Perni S, Franzini-Armstrong C, Beam KG, Grabner M. The distal C terminus of the dihydropyridine receptor ß(1a) subunit is essential for tetrad formation in skeletal muscle. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2201136119. PubMed PMID: 35507876
  • Perni S, Beam K. Junctophilins 1, 2, and 3 all support voltage-induced Ca2 release despite considerable divergence. J Gen Physiol. 2022 Sep 5;154(9). PubMed PMID: 35089322
  • Perni S, Beam K. Neuronal junctophilins recruit specific Ca(V) and RyR isoforms to ER-PM junctions and functionally alter Ca(V)2.1 and Ca(V)2.2. Elife. 2021 Mar 26;10. PubMed PMID: 33769283
  • Polster A, Perni S, Filipova D, Moua O, Ohrtman JD, Bichraoui H, Beam KG, Papadopoulos S. Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain. J Gen Physiol. 2018 Feb 5;150(2):293-306. PubMed PMID: 29284662
  • Polster A, Nelson BR, Papadopoulos S, Olson EN, Beam KG. Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of Ca(V)1.1. J Gen Physiol. 2018 Feb 21. [Epub ahead of print] PubMed PMID: 29467163
  • Polster A, Dittmer PJ, Perni S, Bichraoui H, Sather WA, Beam KG. Stac Proteins Suppress Ca(2 )-Dependent Inactivation of Neuronal l-type Ca(2 ) Channels. J Neurosci. 2018 Oct 24;38(43):9215-9227. PubMed PMID: 30201773
  • Polster A, Nelson BR, Papadopoulos S, Olson EN, Beam KG. Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of Ca(V)1.1. J Gen Physiol. 2018 Apr 2;150(4):613-624. PubMed PMID: 29467163
  • Polster A, Perni S, Filipova D, Moua O, Ohrtman JD, Bichraoui H, Beam KG, Papadopoulos S. Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain. J Gen Physiol. 2018 Feb 5;150(2):293-306. PubMed PMID: 29284662
  • Perni S, Lavorato M, Beam KG. De novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca(2 ) release. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13822-13827. PubMed PMID: 29229815
  • Polster A, Nelson BR, Olson EN, Beam KG. Stac3 has a direct role in skeletal muscle-type excitation-contraction coupling that is disrupted by a myopathy-causing mutation. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10986-91. PubMed PMID: 27621462
  • Bannister RA, Sheridan DC, Beam KG. Distinct Components of Retrograde Ca(V)1.1-RyR1 Coupling Revealed by a Lethal Mutation in RyR1. Biophys J. 2016 Feb 23;110(4):912-21. PubMed PMID: 26910427
  • Polster A, Perni S, Bichraoui H, Beam KG. Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca2 channels. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):602-6. PubMed PMID: 25548159
  • Ohrtman JD, Romberg CF, Moua O, Bannister RA, Levinson SR, Beam KG. Apparent lack of physical or functional interaction between CaV1.1 and its distal C terminus. J Gen Physiol. 2015 Apr;145(4):303-14. PubMed PMID: 25779869
  • Polster A, Perni S, Bichraoui H, Beam KG. Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca2 channels. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):602-6. PubMed PMID: 25548159
  • Bannister RA, Beam KG. Impaired gating of an L-Type Ca(2 ) channel carrying a mutation linked to malignant hyperthermia. Biophys J. 2013 May 7;104(9):1917-22. PubMed PMID: 23663834
  • Bannister RA, Beam KG. Ca(V)1.1: The atypical prototypical voltage-gated Ca²? channel. Biochim Biophys Acta. 2013 Jul;1828(7):1587-97. PubMed PMID: 22982493
  • Flucher BE, Beam KG. . The skeletal muscle calcium channel. In: Voltage-Gated Calcium Channels (Zamponi, GW and Weiss, N., eds.) Springer Nature Books, in press.
View All (19 Total) View Less

General Information

Department: Physiology & Biophysics
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

Update My Profile
;