Shelley Miyamoto, MD

Professional Titles

• Chief, Pediatric Cardiology
• Co-Director of the Heart Institute
• Selby's Chair in Pediatric Cardiology
• Jack Cooper Millisor Chair in Pediatric Heart Disease

Recognitions

• Medical Student Teaching Award, School of Medicine Class of 2013 (2010)
  Medical Student Teaching Award: Best Clinical Correlates.
• Fern Primack Heart Who Cares Award, Heart Institute at Children's Hospital Colorado (2009)
  Nominated by peers and colleagues in recognition of dedication to the Heart Institute and Cardiac patient families. Awarded by the Little Hearts Committee
• Cardiovascular Scholar Award Winner, American Federation for Medical Research (2006)
  Awarded for abstract presentation titled, "Cell-specific Responses in an Apoptotic Model of Viral Myocarditis"
• Top Doctor in Denver, 5280 Magazine (2015)
  Voted a 5280 best doctor by my peers in response to the question, "Which physician would you trust to treat you and your family?"
• University of Iowa Roy J. and Lucille Carver College of Medicine Distinguished Alumnus Achievement Award, University of Iowa School of Medicine (2019)
• University of Iowa Roy J. and Lucille Carver College of Medicine Distinguished Alumnus Achievement Award, University of Iowa School of Medicine (2019)

Research Interests

Publications

• Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-Dimer, and Risk of Poor Neurologic Outcome in Childhood-Onset Arterial Ischemic Stroke. J Pediatr. 2012 Dec 19. [Epub ahead of print] PubMed PMID: 23260102
• Hancock HS, Wang M, Gist KM, Gibson E, Miyamoto SD, Mourani PM, Manco-Johnson MJ, Goldenberg NA. Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study. Cardiol Young. 2012 Oct 22;:1-9. [Epub ahead of print] PubMed PMID: 23088931
• Miyamoto SD, Stauffer BL, Nakano S, Sobus R, Nunley K, Nelson P, Sucharov CC. Beta-adrenergic adaptation in paediatric idiopathic dilated cardiomyopathy. Eur Heart J. 2012 Jul 26. [Epub ahead of print] PubMed PMID: 22843448
• Auerbach SR, Smith JK, Gralla J, Mitchell MB, Campbell DN, Jaggers J, Pietra BA, Miyamoto SD. Graft survival is better without prior surgery in cardiac transplantation for functionally univentricular hearts. J Heart Lung Transplant. 2012 Sep;31(9):987-95. PubMed PMID: 22789137
• Kailin JA, Miyamoto SD, Younoszai AK, Landeck BF. Longitudinal myocardial deformation is selectively decreased after pediatric cardiac transplantation: a comparison of children 1 year after transplantation with normal subjects using velocity vector imaging. Pediatr Cardiol. 2012 Jun;33(5):749-56. PubMed PMID: 22367550
• Moon TJ, Miyamoto SD, Younoszai AK, Landeck BF. Left ventricular strain and strain rates are decreased in children with normal fractional shortening after exposure to anthracycline chemotherapy. Cardiol Young. 2013 Sep 18;:1-12. [Epub ahead of print] PubMed PMID: 24044518
• Friesen RH, Nichols CS, Twite MD, Cardwell KA, Pan Z, Pietra B, Miyamoto SD, Auerbach SR, Darst JR, Ivy DD. The hemodynamic response to dexmedetomidine loading dose in children with and without pulmonary hypertension. Anesth Analg. 2013 Oct;117(4):953-9. PubMed PMID: 23960035
• Conway J, Chrisant MR, West LJ, Ameduri RK, Alejos JC, Lamour JM, Das B, Gilbert D, Tresler M, Naftel DC, Miyamoto SD. Outcomes of fetal listed patients awaiting heart transplantation. Pediatr Transplant. 2013 Nov;17(7):653-60. PubMed PMID: 23919733
• Nakano SJ, Miyamoto SD, Movsesian M, Nelson P, Stauffer BL, Sucharov CC. Age-Related Differences in Phosphodiesterase Activity and Effects of Chronic Phosphodiesterase Inhibition in Idiopathic Dilated Cardiomyopathy. Circ Heart Fail. 2014 Oct 2. [Epub ahead of print] PubMed PMID: 25278000
• Sucharov CC, Hijmans JG, Sobus RD, Melhado WF, Miyamoto SD, Stauffer BL. ß-Adrenergic receptor antagonism in mice: a model for pediatric heart disease. J Appl Physiol (1985). 2013 Oct 1;115(7):979-87. PubMed PMID: 23887897
• Chatfield KC, Sparagna GC, Sucharov CC, Miyamoto SD, Grudis JE, Sobus RD, Hijmans J, Stauffer BL. Dysregulation of cardiolipin biosynthesis in pediatric heart failure. J Mol Cell Cardiol. 2014 Sep;74:251-9. PubMed PMID: 24937604
• Miyamoto SD, Stauffer BL, Polk J, Medway A, Friedrich M, Haubold K, Peterson V, Nunley K, Nelson P, Sobus R, Stenmark KR, Sucharov CC. Gene expression and ß-adrenergic signaling are altered in hypoplastic left heart syndrome. J Heart Lung Transplant. 2014 Aug;33(8):785-93. PubMed PMID: 24793904
• Dipchand AI, Kirk R, Mahle WT, Tresler MA, Naftel DC, Pahl E, Miyamoto SD, Blume E, Guleserian KJ, White-Williams C, Kirklin JK. Ten yr of pediatric heart transplantation: a report from the Pediatric Heart Transplant Study. Pediatr Transplant. 2013 Mar;17(2):99-111. PubMed PMID: 23442098
• Castleberry C, White-Williams C, Naftel D, Tresler MA, Pruitt E, Miyamoto SD, Murphy D, Spicer R, Bannister L, Schowengerdt K, Gilmore L, Kaufman B, Zangwill S. Hypoalbuminemia and poor growth predict worse outcomes in pediatric heart transplant recipients. Pediatr Transplant. 2014 May;18(3):280-7. PubMed PMID: 24646199
• Stauffer BL, Russell G, Nunley K, Miyamoto SD, Sucharov CC. miRNA expression in pediatric failing human heart. J Mol Cell Cardiol. 2013 Apr;57:43-6. PubMed PMID: 23333438
• Boucek D, Yetman AT, Yeung E, Miyamoto SD, Stehlik J, Kfoury AG, Kaza AK, Weng C, Everitt MD. Survival based on patient selection for heart transplant in adults with congenital heart disease: a multi-institutional study. Int J Cardiol. 2014;172(1):e89-90. PubMed PMID: 24433616
• Auerbach SR, Gralla J, Campbell DN, Miyamoto SD, Pietra BA. Steroid avoidance in pediatric heart transplantation results in excellent graft survival. Transplantation. 2014 Feb 27;97(4):474-80. PubMed PMID: 24389908
• Moon TJ, Miyamoto SD, Younoszai AK, Landeck BF. Left ventricular strain and strain rates are decreased in children with normal fractional shortening after exposure to anthracycline chemotherapy. Cardiol Young. 2014 Oct;24(5):854-65. PubMed PMID: 24044518
• Miyamoto SD, Stauffer BL, Nakano S, Sobus R, Nunley K, Nelson P, Sucharov CC. Beta-adrenergic adaptation in paediatric idiopathic dilated cardiomyopathy. Eur Heart J. 2014 Jan;35(1):33-41. PubMed PMID: 22843448
• Kirk R, Dipchand AI, Rosenthal DN, Addonizio L, Burch M, Chrisant M, Dubin A, Everitt M, Gajarski R, Mertens L, Miyamoto S, Morales D, Pahl E, Shaddy R, Towbin J, Weintraub R. The International Society of Heart and Lung Transplantation Guidelines for the management of pediatric heart failure: executive summary. J Heart Lung Transplant. 2014 Sep;33(9):888-909. PubMed PMID: 25110323
• Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke. J Pediatr. 2013 May;162(5):1041-6.e1. PubMed PMID: 23260102
• Schwartz LI, Miyamoto SD, Stenquist S, Twite MD. Cardiac Arrest in a Heart Transplant Patient Receiving Dexmedetomidine During Cardiac Catheterization. Semin Cardiothorac Vasc Anesth. 2015 Dec 31. [Epub ahead of print] PubMed PMID: 26721807
• Friesen RH, Twite MD, Nichols CS, Cardwell KA, Pan Z, Darst JR, Wilson N, Fagan TE, Miyamoto SD, Ivy DD. Hemodynamic response to ketamine in children with pulmonary hypertension. Paediatr Anaesth. 2016 Jan;26(1):102-8. PubMed PMID: 26564806
• Hancock HS, Wang M, Gist KM, Gibson E, Miyamoto SD, Mourani PM, Manco-Johnson MJ, Goldenberg NA. Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study. Cardiol Young. 2013 Jun;23(3):344-52. PubMed PMID: 23088931
• Cortez D, Sharma N, Cavanaugh J, Tuozo F, Derk G, Lundberg E, Schlegel TT, Weiner K, Kiciman N, Alejos J, Landeck B, Aboulhosn J, Miyamoto S, Batra A, McCanta AC. The spatial QRS-T angle outperforms the Italian and Seattle ECG-based criteria for detection of hypertrophic cardiomyopathy in pediatric patients. J Electrocardiol. 2015 Sep-Oct;48(5):826-33. PubMed PMID: 26275983
• Auerbach SR, Kukreja M, Gilbert D, Bastardi H, Feingold B, Knecht K, Kaufman BD, Brown RN, Miyamoto SD. Maintenance steroid use at 30 days post-transplant and outcomes of pediatric heart transplantation: A propensity matched analysis of the Pediatric Heart Transplant Study database. J Heart Lung Transplant. 2015 Aug;34(8):1066-72. PubMed PMID: 25980572
• Nakano SJ, Miyamoto SD, Movsesian M, Nelson P, Stauffer BL, Sucharov CC. Age-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy. Circ Heart Fail. 2015 Jan;8(1):57-63. PubMed PMID: 25278000
• Sucharov CC, Sucharov J, Karimpour-Fard A, Nunley K, Stauffer BL, Miyamoto SD. Micro-RNA expression in hypoplastic left heart syndrome. J Card Fail. 2015 Jan;21(1):83-8. PubMed PMID: 25291457
• Miyamoto SD, Karimpour-Fard A, Peterson V, Auerbach SR, Stenmark KR, Stauffer BL, Sucharov CC. Circulating microRNA as a biomarker for recovery in pediatric dilated cardiomyopathy. J Heart Lung Transplant. 2015 May;34(5):724-33. PubMed PMID: 25840506
• Glidewell SC, Miyamoto SD, Grossfeld PD, Clouthier DE, Coldren CD, Stearman RS, Geraci MW. Transcriptional Impact of Rare and Private Copy Number Variants in Hypoplastic Left Heart Syndrome. Clin Transl Sci. 2015 Nov 4. [Epub ahead of print] PubMed PMID: 26534787
• Zoeller BB, Miyamoto SD, Younoszai AK, Landeck BF 2nd. Longitudinal Strain and Strain Rate Abnormalities Precede Invasive Diagnosis of Transplant Coronary Artery Vasculopathy in Pediatric Cardiac Transplant Patients. Pediatr Cardiol. 2016 Apr;37(4):656-62. PubMed PMID: 26818849
• Friesen RH, Twite MD, Nichols CS, Cardwell KA, Pan Z, Darst JR, Wilson N, Fagan TE, Miyamoto SD, Ivy DD. Hemodynamic response to ketamine in children with pulmonary hypertension. Paediatr Anaesth. 2016 Jan;26(1):102-8. PubMed PMID: 26564806
• Schwartz LI, Miyamoto SD, Stenquist S, Twite MD. Cardiac Arrest in a Heart Transplant Patient Receiving Dexmedetomidine During Cardiac Catheterization. Semin Cardiothorac Vasc Anesth. 2016 Jun;20(2):175-8. PubMed PMID: 26721807
• Yu HC, Coughlin CR, Geiger EA, Salvador BJ, Elias ER, Cavanaugh JL, Chatfield KC, Miyamoto SD, Shaikh TH. Discovery of a potentially deleterious variant in TMEM87B in a patient with a hemizygous 2q13 microdeletion suggests a recessive condition characterized by congenital heart disease and restrictive cardiomyopathy. Cold Spring Harb Mol Case Stud. 2016 May;2(3):a000844. PubMed PMID: 27148590
• Cortez D, Sharma N, Cavanaugh J, Tuozo F, Derk G, Lundberg E, Weiner K, Kiciman N, Alejos J, Landeck B, Aboulhosn J, Miyamoto S, McCanta AC, Batra AS. Lower spatial QRS-T angle rules out sustained ventricular arrhythmias in children with hypertrophic cardiomyopathy. Cardiol Young. 2016 Jun 1;:1-5. [Epub ahead of print] PubMed PMID: 27246458
• Nakano SJ, Nelson P, Sucharov CC, Miyamoto SD. Myocardial Response to Milrinone in Single Right Ventricle Heart Disease. J Pediatr. 2016 Jul;174:199-203.e5. PubMed PMID: 27181939
• Nandi D, Miyamoto SD, Pietra BA, Shaddy RE, Rossano JW. Donation after circulatory death in pediatric patients: Current utilization in the United States. J Heart Lung Transplant. 2016 Sep;35(9):1131-2. PubMed PMID: 27363738
• Grady KL, Hof KV, Andrei AC, Shankel T, Chinnock R, Miyamoto S, Ambardekar AV, Anderson A, Addonizio L, Latif F, Lefkowitz D, Goldberg L, Hollander SA, Pham M, Weissberg-Benchell J, Cool N, Yancy C, Pahl E. Pediatric Heart Transplantation: Transitioning to Adult Care (TRANSIT): Baseline Findings. Pediatr Cardiol. 2017 Nov 3. [Epub ahead of print] PubMed PMID: 29098353
• Nakano SJ, Siomos AK, Garcia AM, Nguyen H, SooHoo M, Galambos C, Nunley K, Stauffer BL, Sucharov CC, Miyamoto SD. Fibrosis-Related Gene Expression in Single Ventricle Heart Disease. J Pediatr. 2017 Dec;191:82-90.e2. PubMed PMID: 29050751
• Boruta RJ, Miyamoto SD, Younoszai AK, Patel SS, Landeck BF 2nd. Worsening in Longitudinal Strain and Strain Rate Anticipates Development of Pediatric Transplant Coronary Artery Vasculopathy as Soon as One Year Following Transplant. Pediatr Cardiol. 2017 Sep 25. [Epub ahead of print] PubMed PMID: 28948364
• Kheyfets VO, Sucharov CC, Truong U, Dunning J, Hunter K, Ivy D, Miyamoto S, Shandas R. Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function. Oxid Med Cell Longev. 2017;2017:4957147. PubMed PMID: 28819545
• Tatman PD, Woulfe KC, Karimpour-Fard A, Jeffrey DA, Jaggers J, Cleveland JC, Nunley K, Taylor MR, Miyamoto SD, Stauffer BL, Sucharov CC. Pediatric dilated cardiomyopathy hearts display a unique gene expression profile. JCI Insight. 2017 Jul 20;2(14). [Epub ahead of print] PubMed PMID: 28724804
• Blakeslee WW, Demos-Davies KM, Lemon DD, Lutter KM, Cavasin MA, Payne S, Nunley K, Long CS, McKinsey TA, Miyamoto SD. Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy. Pediatr Res. 2017 Oct;82(4):642-649. PubMed PMID: 28549058
• Friesen RH, Slavov D, Miyamoto SD, John Ing R, LaRiviere WB, Taylor MRG. Lack of Association Between Adrenoreceptor Genotype and the Vasoconstriction Response to Dexmedetomidine. Semin Cardiothorac Vasc Anesth. 2017 Dec;21(4):341-344. PubMed PMID: 28482761
• Woulfe KC, Siomos AK, Nguyen H, SooHoo M, Galambos C, Stauffer BL, Sucharov C, Miyamoto S. Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy. J Card Fail. 2017 Apr;23(4):314-324. PubMed PMID: 27890770
• Jiang X, Sucharov J, Stauffer BL, Miyamoto SD, Sucharov CC. Exosomes from pediatric dilated cardiomyopathy patients modulate a pathological response in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H818-H826. PubMed PMID: 28130338
• Nakano SJ, Sucharov J, van Dusen R, Cecil M, Nunley K, Wickers S, Karimpur-Fard A, Stauffer BL, Miyamoto SD, Sucharov CC. Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment. J Card Fail. 2017 Jan;23(1):72-80. PubMed PMID: 27427220
• Medina E, Sucharov CC, Nelson P, Miyamoto SD, Stauffer BL. Molecular Changes in Children with Heart Failure Undergoing Left Ventricular Assist Device Therapy. J Pediatr. 2017 Mar;182:184-189.e1. PubMed PMID: 27908653
• Nakano SJ, Miyamoto SD, Price JF, Rossano JW, Cabrera AG. Pediatric Heart Failure: An Evolving Public Health Concern. J Pediatr. 2019 Nov 15. [Epub ahead of print] PubMed PMID: 31740144
• Nakano SJ, Walker JS, Walker LA, Li X, Du Y, Miyamoto SD, Sucharov CC, Garcia AM, Mitchell MB, Ambardekar AV, Stauffer BL. Increased myocyte calcium sensitivity in end-stage pediatric dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2019 Dec 1;317(6):H1221-H1230. PubMed PMID: 31625780
• Chatfield KC, Sparagna GC, Chau S, Phillips EK, Ambardekar AV, Aftab M, Mitchell MB, Sucharov CC, Miyamoto SD, Stauffer BL. Elamipretide Improves Mitochondrial Function in the Failing Human Heart. JACC Basic Transl Sci. 2019 Apr;4(2):147-157. PubMed PMID: 31061916
• Watanabe K, Schafer M, Cassidy C, Miyamoto SD, Jone PN. Right Atrial Function in Pediatric Heart Transplant Patients Utilizing Right Atrial Strain. Pediatric Transplantation, 2019 Mar 13:e13383.
• Grady KL, Andrei A, Shankel T, Chinnock R, Miyamoto SD, Ambardekar AV, Anderson A, Addonizio L, Latif R, Lefkowitz D, Goldberg L, Hollander S, Pham M, Van’t Ho K, Weissberg-Benchell J, Yancy C, Liu M, Cool N, Pahl E. Pediatric Heart Transplantation: Transitioning to Adult Care (TRANSIT). J Card Failure, accepted June 21, 2019.
• Wall JB, Garcia AM, Jacobsen RM, Miyamoto SD. Important Considerations in Pediatric Heart Failure. Curr Cardiol Rep. 2020 Sep 10;22(11):141. PubMed PMID: 32910348
• Jone PN, Korst A, Karimpour-Fard A, Thomas T, Dominguez SR, Heizer H, Anderson MS, Glode MP, Sucharov CC, Miyamoto SD. Circulating microRNAs differentiate Kawasaki Disease from infectious febrile illnesses in childhood. J Mol Cell Cardiol. 2020 Sep;146:12-18. PubMed PMID: 32634388
• Chatfield KC, Sparagna GC, Specht KS, Whitcomb LA, Omar AK, Miyamoto SD, Wolfe LM, Chicco AJ. Long-chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy. J Inherit Metab Dis. 2021 Nov 25. [Epub ahead of print] PubMed PMID: 34821394
• Fraley C, Milgrom SA, Kondapalli L, Taylor MRG, Mestroni L, Miyamoto SD. Mechanisms and Insights for the Development of Heart Failure Associated with Cancer Therapy. Children (Basel). 2021 Sep 21;8(9). PubMed PMID: 34572260
• Jeffrey DA, Pires Da Silva J, Garcia AM, Jiang X, Karimpour-Fard A, Toni LS, Lanzicher T, Peña B, Miyano CA, Nunley K, Korst A, Sbaizero O, Taylor MR, Miyamoto SD, Stauffer BL, Sucharov CC. Serum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness. JCI Insight. 2021 Oct 8;6(19). PubMed PMID: 34383712
• Willner EC, Galan HL, Cuneo BF, Hoffman HA, Neltner B, Schuchardt EL, Karimpour-Fard A, Miyamoto SD, Sucharov CC. Amniotic fluid microRNA profiles in twin-twin transfusion syndrome with and without severe recipient cardiomyopathy. Am J Obstet Gynecol. 2021 Oct;225(4):439.e1-439.e10. PubMed PMID: 34153234
• Woulfe KC, Jeffrey DA, Pires Da Silva J, Wilson CE, Mahaffey JH, Lau E, Slavov D, Hailu F, Karimpour-Fard A, Dockstader K, Bristow MR, Stauffer BL, Miyamoto SD, Sucharov CC. Serum response factor deletion 5 regulates phospholamban phosphorylation and calcium uptake. J Mol Cell Cardiol. 2021 Oct;159:28-37. PubMed PMID: 34139234
• Hailu FT, Karimpour-Fard A, Toni LS, Bristow MR, Miyamoto SD, Stauffer BL, Sucharov CC. Integrated analysis of miRNA-mRNA interaction in pediatric dilated cardiomyopathy. Pediatr Res. 2021 May 19. [Epub ahead of print] PubMed PMID: 34012027
• Opotowsky AR, Allen KY, Bucholz EM, Burns KM, Del Nido P, Fenton KN, Gelb BD, Kirkpatrick JN, Kutty S, Lambert LM, Lopez KN, Olivieri LJ, Pajor NM, Pasquali SK, Petit CJ, Sood E, VanBuren JM, Pearson GD, Miyamoto SD. Pediatric and Congenital Cardiovascular Disease Research Challenges and Opportunities: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 Dec 6;80(23):2239-2250. PubMed PMID: 36456054
• Stone ML, Albertz ML, Galambos C, Twite MD, Campbell DN, Di Maria M, Fonseca B, Miyamoto SD, Ing RJ. Multi-Disciplinary Management and Surgical Resection of Intracardiac Fibromas Causing Bilateral Ventricular Outflow Tract Obstructions in an Infant. Semin Cardiothorac Vasc Anesth. 2022 Dec;26(4):315-322. PubMed PMID: 36006828
• Baybayon-Grandgeorge AN, Pietra AE, Miyamoto SD, Garcia AM. Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome. J Cardiovasc Dev Dis. 2022 May 12;9(5). PubMed PMID: 35621863
• Jone PN, John A, Oster ME, Allen K, Tremoulet AH, Saarel EV, Lambert LM, Miyamoto SD, de Ferranti SD. SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association. Circulation. 2022 May 10;145(19):e1037-e1052. PubMed PMID: 35400169
• Schuchardt EL, Miyamoto SD, Crombleholme T, Karimpour-Fard A, Korst A, Neltner B, Howley LW, Cuneo B, Sucharov CC. Amniotic Fluid microRNA in Severe Twin-Twin Transfusion Syndrome Cardiomyopathy-Identification of Differences and Predicting Demise. J Cardiovasc Dev Dis. 2022 Jan 23;9(2). PubMed PMID: 35200691
• Chatfield KC, Sparagna GC, Specht KS, Whitcomb LA, Omar AK, Miyamoto SD, Wolfe LM, Chicco AJ. Long-chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy. J Inherit Metab Dis. 2022 Jan;45(1):111-124. PubMed PMID: 34821394
• Fraley C, Milgrom SA, Kondapalli L, Taylor MRG, Mestroni L, Miyamoto SD. Mechanisms and Insights for the Development of Heart Failure Associated with Cancer Therapy. Children (Basel). 2021 Sep 21;8(9). PubMed PMID: 34572260
• Jeffrey DA, Pires Da Silva J, Garcia AM, Jiang X, Karimpour-Fard A, Toni LS, Lanzicher T, Peña B, Miyano CA, Nunley K, Korst A, Sbaizero O, Taylor MR, Miyamoto SD, Stauffer BL, Sucharov CC. Serum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness. JCI Insight. 2021 Oct 8;6(19). PubMed PMID: 34383712
• Willner EC, Galan HL, Cuneo BF, Hoffman HA, Neltner B, Schuchardt EL, Karimpour-Fard A, Miyamoto SD, Sucharov CC. Amniotic fluid microRNA profiles in twin-twin transfusion syndrome with and without severe recipient cardiomyopathy. Am J Obstet Gynecol. 2021 Oct;225(4):439.e1-439.e10. PubMed PMID: 34153234
• Stevens CG, Kay J, Pickett K, Campbell K, Khanna AD, Yeung E, Miyamoto SD, Jacobsen RM. Predictors of Poor Functional Status in Adult Fontan Patients Living at Moderate Altitude. Pediatr Cardiol. 2021 Dec;42(8):1757-1765. PubMed PMID: 34143227
• Woulfe KC, Jeffrey DA, Pires Da Silva J, Wilson CE, Mahaffey JH, Lau E, Slavov D, Hailu F, Karimpour-Fard A, Dockstader K, Bristow MR, Stauffer BL, Miyamoto SD, Sucharov CC. Serum response factor deletion 5 regulates phospholamban phosphorylation and calcium uptake. J Mol Cell Cardiol. 2021 Oct;159:28-37. PubMed PMID: 34139234
• Lin Y, Davis TJ, Zorrilla-Vaca A, Wojcik BM, Miyamoto SD, Everitt MD, Campbell DN, Jaggers JJ, Rajab TK. Neonatal heart transplant outcomes: A single institutional experience. J Thorac Cardiovasc Surg. 2021 Nov;162(5):1361-1368. PubMed PMID: 34099271
• Hailu FT, Karimpour-Fard A, Toni LS, Bristow MR, Miyamoto SD, Stauffer BL, Sucharov CC. Integrated analysis of miRNA-mRNA interaction in pediatric dilated cardiomyopathy. Pediatr Res. 2022 Jul;92(1):98-108. PubMed PMID: 34012027
• Gist KM, Korst A, Nakano SJ, Stauffer BL, Karimpour-Fard A, Zhou W, Campbell K, Wempe MF, Sucharov CC, Miyamoto SD. Circulating cyclic adenosine monophosphate concentrations in milrinone treated paediatric patients after congenital heart surgery. Cardiol Young. 2021 Sep;31(9):1393-1400. PubMed PMID: 33533327
• Hailu FT, Karimpour-Fard A, Neltner B, Stauffer BL, Lipshultz S, Miyamoto SD, Sucharov CC. Circulating and Cardiac Tissue miRNAs in Children with Dilated Cardiomyopathy. J Cardiovasc Dev Dis. 2023 Sep 11;10(9). PubMed PMID: 37754820
• Fernie JC, Wylie L, Schäfer M, Carnegie K, Miyamoto SD, Jacobsen RM. Pilot Project: Heart Chargers-A Successful Model for a Home-Based Physical Activity Program Utilizing Telemedicine for Fontan Patients. Pediatr Cardiol. 2023 Oct;44(7):1506-1513. PubMed PMID: 37347244
• Bogle C, Colan SD, Miyamoto SD, Choudhry S, Baez-Hernandez N, Brickler MM, Feingold B, Lal AK, Lee TM, Canter CE, Lipshultz SE. Treatment Strategies for Cardiomyopathy in Children: A Scientific Statement From the American Heart Association. Circulation. 2023 Jul 11;148(2):174-195. PubMed PMID: 37288568
• Garcia AM, Toni LS, Miyano CA, Sparagna GC, Jonscher R, Phillips EK, Karimpour-Fard A, Chapman HL, Baybayon-Grandgeorge AN, Pietra AE, Selner E, Chatfield KC, Stauffer BL, Sucharov CC, Miyamoto SD. Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single-Ventricle Congenital Heart Disease. JACC Basic Transl Sci. 2023 Mar;8(3):258-279. PubMed PMID: 37034285
• Sucharov CC, Neltner B, Pietra AE, Karimpour-Fard A, Patel J, Ho CY, Miyamoto SD. Circulating MicroRNAs Identify Early Phenotypic Changes in Sarcomeric Hypertrophic Cardiomyopathy. Circ Heart Fail. 2023 Jun;16(6):e010291. PubMed PMID: 36880380
• Almond CS, Sleeper LA, Rossano JW, Bock MJ, Pahl E, Auerbach S, Lal A, Hollander SA, Miyamoto SD, Castleberry C, Lee J, Barkoff LM, Gonzales S, Klein G, Daly KP. The teammate trial: Study design and rationale tacrolimus and everolimus against tacrolimus and MMF in pediatric heart transplantation using the major adverse transplant event (MATE) score. Am Heart J. 2023 Jun;260:100-112. PubMed PMID: 36828201
• Opotowsky AR, Allen KY, Bucholz EM, Burns KM, Del Nido P, Fenton KN, Gelb BD, Kirkpatrick JN, Kutty S, Lambert LM, Lopez KN, Olivieri LJ, Pajor NM, Pasquali SK, Petit CJ, Sood E, VanBuren JM, Pearson GD, Miyamoto SD. Pediatric and Congenital Cardiovascular Disease Research Challenges and Opportunities: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 Dec 6;80(23):2239-2250. PubMed PMID: 36456054
• Stone ML, Albertz ML, Galambos C, Twite MD, Campbell DN, Di Maria M, Fonseca B, Miyamoto SD, Ing RJ. Multi-Disciplinary Management and Surgical Resection of Intracardiac Fibromas Causing Bilateral Ventricular Outflow Tract Obstructions in an Infant. Semin Cardiothorac Vasc Anesth. 2022 Dec;26(4):315-322. PubMed PMID: 36006828
• Chan M, Silveira L, Patterson DJ, Bock ME, Pietra BA, Everitt MD, Simpson KE, Miyamoto SD, Auerbach SR. Longitudinal Changes in Estimated Glomerular Filtration Rate Following Repeat Heart Transplant in Children and Young Adults. Pediatr Transplant. 2024 Nov;28(7):e14875. PubMed PMID: 39412399
• Amdani S, Conway J, George K, Martinez HR, Asante-Korang A, Goldberg CS, Davies RR, Miyamoto SD, Hsu DT. Evaluation and Management of Chronic Heart Failure in Children and Adolescents With Congenital Heart Disease: A Scientific Statement From the American Heart Association. Circulation. 2024 Jul 9;150(2):e33-e50. PubMed PMID: 38808502
• Baybayon-Grandgeorge AN, Pietra AE, Miyamoto SD, Garcia AM. Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome. J Cardiovasc Dev Dis. 2022 May 12;9(5). PubMed PMID: 35621863
• Schäfer M, Miyamoto SD, Jaggers J, Everitt MD, von Alvensleben JC, Campbell DN, Mitchell MB, Stone ML. Non-invasive myocardial tissue deformation and discoordination indices predict cardiac allograft vasculopathy in pediatric heart transplantation patients. Int J Cardiovasc Imaging. 2024 Jul;40(7):1565-1574. PubMed PMID: 38780709
• Amdani S, Auerbach SR, Bansal N, Chen S, Conway J, Silva JPD, Deshpande SR, Hoover J, Lin KY, Miyamoto SD, Puri K, Price J, Spinner J, White R, Rossano JW, Bearl DW, Cousino MK, Catlin P, Hidalgo NC, Godown J, Kantor P, Masarone D, Peng DM, Rea KE, Schumacher K, Shaddy R, Shea E, Tapia HV, Valikodath N, Zafar F, Hsu D. Research Gaps in Pediatric Heart Failure: Defining the Gaps and Then Closing Them Over the Next Decade. J Card Fail. 2024 Jan;30(1):64-77. PubMed PMID: 38065308
• Jone PN, John A, Oster ME, Allen K, Tremoulet AH, Saarel EV, Lambert LM, Miyamoto SD, de Ferranti SD. SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association. Circulation. 2022 May 10;145(19):e1037-e1052. PubMed PMID: 35400169
• Schuchardt EL, Miyamoto SD, Crombleholme T, Karimpour-Fard A, Korst A, Neltner B, Howley LW, Cuneo B, Sucharov CC. Amniotic Fluid microRNA in Severe Twin-Twin Transfusion Syndrome Cardiomyopathy-Identification of Differences and Predicting Demise. J Cardiovasc Dev Dis. 2022 Jan 23;9(2). PubMed PMID: 35200691
• Chatfield KC, Sparagna GC, Specht KS, Whitcomb LA, Omar AK, Miyamoto SD, Wolfe LM, Chicco AJ. Long-chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy. J Inherit Metab Dis. 2022 Jan;45(1):111-124. PubMed PMID: 34821394
• Hailu FT, Karimpour-Fard A, Toni LS, Bristow MR, Miyamoto SD, Stauffer BL, Sucharov CC. Integrated analysis of miRNA-mRNA interaction in pediatric dilated cardiomyopathy. Pediatr Res. 2022 Jul;92(1):98-108. PubMed PMID: 34012027
• Chan M, Silveira L, Patterson DJ, Bock ME, Pietra BA, Everitt MD, Simpson KE, Miyamoto SD, Auerbach SR. Changes in estimated glomerular filtration rate over the first year following repeat heart transplant in children and young adults. Pediatr Transplant. 2024 Feb;28(1):e14651. PubMed PMID: 38015081
• Fernie JC, Wylie L, Schäfer M, Carnegie K, Miyamoto SD, Jacobsen RM. Pilot Project: Heart Chargers-A Successful Model for a Home-Based Physical Activity Program Utilizing Telemedicine for Fontan Patients. Pediatr Cardiol. 2023 Oct;44(7):1506-1513. PubMed PMID: 37347244
• Bogle C, Colan SD, Miyamoto SD, Choudhry S, Baez-Hernandez N, Brickler MM, Feingold B, Lal AK, Lee TM, Canter CE, Lipshultz SE. Treatment Strategies for Cardiomyopathy in Children: A Scientific Statement From the American Heart Association. Circulation. 2023 Jul 11;148(2):174-195. PubMed PMID: 37288568
• Garcia AM, Toni LS, Miyano CA, Sparagna GC, Jonscher R, Phillips EK, Karimpour-Fard A, Chapman HL, Baybayon-Grandgeorge AN, Pietra AE, Selner E, Chatfield KC, Stauffer BL, Sucharov CC, Miyamoto SD. Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single-Ventricle Congenital Heart Disease. JACC Basic Transl Sci. 2023 Mar;8(3):258-279. PubMed PMID: 37034285
• Sucharov CC, Neltner B, Pietra AE, Karimpour-Fard A, Patel J, Ho CY, Miyamoto SD. Circulating MicroRNAs Identify Early Phenotypic Changes in Sarcomeric Hypertrophic Cardiomyopathy. Circ Heart Fail. 2023 Jun;16(6):e010291. PubMed PMID: 36880380
• Almond CS, Sleeper LA, Rossano JW, Bock MJ, Pahl E, Auerbach S, Lal A, Hollander SA, Miyamoto SD, Castleberry C, Lee J, Barkoff LM, Gonzales S, Klein G, Daly KP. The teammate trial: Study design and rationale tacrolimus and everolimus against tacrolimus and MMF in pediatric heart transplantation using the major adverse transplant event (MATE) score. Am Heart J. 2023 Jun;260:100-112. PubMed PMID: 36828201

Professional Memberships

• International Society of Heart and Lung Transplantation, Member
• American Heart Association (AHA), Immediate Past Chair of the Young Hearts Council
• Society of Pediatric Research, Member

Practice Locations

• Children's Hospital Colorado
• University of Colorado Hospital

Specialty Information

• Pediatric Cardiology, Board Certification (2005)
• Pediatrics, Board Certification (2009)

• Heart and Circulation - Cardiomyopathy
• Heart and Circulation - Heart Failure
• Heart and Circulation - Congenital Heart Disease
• Child and Teen Health
• Heart and Circulation