Charles Kirkpatrick, MD

Research Interests

Publications

• Identification of cellular cooperation in antibody production (a tribute to Henry N. Claman, M.D.) J Allergy Clin Immunol 2006; 117:960-962.
• Specific Antibody Deficiency. Ann Allergy Asthma Immunol
• Specific Antibody Deficiency. Ann Allergy Asthma Immunol
• Subcutaneous Immunoglobulin Replcement. A User's manual. for distribution at presentation at the American Academy of Allergy, Asthma and Immunology Annual Meeting.
• Mannose-binding Lectin Deficiency in a Family with Frequent Respiratory Infections. Presented at the 2007 Annual Meeting of the AAAAI.
• 1. Cicardi M, Bane5ji A,....Kirkpatrick CH,... and others. Icatibant, a new Bradykinin Receptor Antagonist, in Hereditary Angioedema. New Engl J Med. 2010;363:532-541. Bradykinin has been shown to be the primary mediator of acute attacks in patients with hereditary angioedema.This paper describes the safety and efficacy of a bradykinin-receptor2 antagonist in treatment of acute attacks of angioedema in these patients. 2.Borish L, Ayers AG, Kirkpatrick CH. Common Variable Immunodeficiency Presenting as Herpes simplex Encephalitis. J Allergy Clin Immunol. 2010 (published online)
• A mechanism for urticaria/angioedema in patients with thyroid disease.
• A mechanism for urticaria/angioedema in patients with thyroid disease
• Zuraw BL, Bork K, Binkley KE, Banerji A, Christiansen SC, Costaldo A, Kaplan A , Riedl, M, Kirkpatrick CH, Magerl M, Drouet C, Cicardi M. Hereditary angioedema with normal C1 inhibitor function: consensus of an International Expert panel. Allergy Asthma Proc 2012; 33: suppl. 1:145-156.
• Malbrán A, Riedl M, Ritchie B, Smith WB, Yang W, Banerji A, Hébert J, Gleich GJ, Hurewitz D, Jacobson KW, Bernstein JA, Khan DA, Kirkpatrick CH, Resnick D, Li H, Fernández Romero DS, Lumry W. Repeat treatment of acute hereditary angioedema attacks with open-label icatibant in the FAST-1 trial. Clin Exp Immunol. 2014 Aug;177(2):544-53. PubMed PMID: 24749847
• Kirkpatrick CH. A mechanism for urticaria/angioedema in patients with thyroid disease. J Allergy Clin Immunol 2012; 130:988-990.
• Zuraw BL, Bork K, Binkley KE, Banerji A, Christiansen SC, Costaldo A, Kaplan A, Riedl, M, Kirkpatrick C, Magerl M, Drouet C, Cicardi M. Hereditary angioedema with normal C1 inhibitor function: consensus of a international expert panel, Allergy Asthma Proc 2012; 33 Suppl 1:145-156.
• Myles IA, et al. including Kirkpatrick CH. "Transfer factors are CD8 derived, antigen specific activators of dendritic cells."
• Myles IA, Zhao M, Nardone G, et al. including Kirkpatrick CH. CD8+ T-cells produce a dialyzable antigen-specific activator of dendritic cells. J Leuko Biol 2016;101:307-320. doi:10.1189/jlb.3A0216-082R
• Sanchez LA, Maggadottir SM, and USIDNET Consortium (Kirkpatrick, CH is a member of the Consortium and contributor to the article). Two sides to the same coin: Pediatric-onset and adult-onset common variable immunodeficiency. J Clin Immunol 2017; 37:592-602. doi:10.1007/s10875-017-045-5
• Giants in Allergy-Immunology. Richard Studley Farr, M.D. https://doi.org/10.1016/j.anal.2018.09.462
• Prevention of apheresis reactions with icatibant

Professional Memberships

• American Academy of Allergy, Asthma & Immunology, Fellow
• American Society for Clinical Investigation, Member
• Clinical Immunology Society, Member
• American Association of Immunologists, Member
• American Academy for Advancement of Science, Member

Practice Locations

• University of Colorado Hospital

Specialty Information

• Internal Medicine, Board Certification
• Allergy and Immunology, Board Certification

• Immune System - Immunodeficiency
• Immune System - Urticaria (Hives)
• Immune System - Angioedema
• Immune System - Sinusitis
• Immune System - Anaphylaxis
• Infections - Fungal Infections
• Infections - Pneumonia
• Lungs and Breathing - Asthma
• Immune System
• Infections
• Lungs and Breathing