Dexiang Gao, PhD, MS

JN Perkins, C Liang, D Gao, L Shultz and NR Friedman. RISK OF POST-TONSILLECTOMY HEMORRHAGE BY CLINICAL DIAGNOSIS. Laryngoscope 122(10):2311-5 (2012) PMID 22778043

Arcaroli JJ, Powell RW, Varella-Garcia M, McManus M, Tan AC, Quackenbush KS, Pitts TM, Gao D, Spreafico A, Dasari A, Touban BM, Messersmith WA. ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a ?-secretase inhibitor and irinotecan in colorectal cancer. Mol Oncol. 2012 Jun;6(3):370-81. doi: 10.1016/j.molonc.2012.03.004. PMID:22521243

Porter CC, Kim J, Fosmire S, Gearheart CM, van Linden A, Baturin D, Zaberezhnyy V, Patel PR, Gao D, Tan AC, DeGregori J. Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia. Leukemia. 2012 Jun;26(6):1266-76. PubMed PMID: 22289989

Jordan KR, Amaria RN, Ramirez O, Callihan EB, Gao D, Borakove M, Manthey E, Borges VF, McCarter MD. Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients. Cancer Immunol Immunother. 2013 Nov;62(11):1711-22. PubMed PMID: 24072401

Chan KH, Gao D, Fernandez PG, Kingdom TT, Kumpe DA. Juvenile nasopharyngeal angiofibroma: Vascular determinates for operative complications and tumor recurrence. Laryngoscope. 2013 Aug 8. [Epub ahead of print] PubMed PMID: 23929652

Jones TS, Jones EL, Gao D, Pearlman NW, Robinson WA, McCarter M. Management of external ear melanoma: the same or something different?. Am J Surg. 2013 Sep;206(3):307-13. PubMed PMID: 23664431

Callihan EB, Gao D, Jindal S, Lyons TR, Manthey E, Edgerton S, Urquhart A, Schedin P, Borges VF. Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. Breast Cancer Res Treat. 2013 Apr;138(2):549-59. PubMed PMID: 23430224

Jones EL, Jones TS, Pearlman NW, Gao D, Stovall R, Gajdos C, Kounalakis N, Gonzalez R, Lewis KD, Robinson WA, McCarter MD. Long-term follow-up and survival of patients following a recurrence of melanoma after a negative sentinel lymph node biopsy result. JAMA Surg. 2013 May;148(5):456-61. PubMed PMID: 23325294

Freehauf C, Van Hove JL, Gao D, Bernstein L, Thomas JA. Impact of geographic access to care on compliance and metabolic control in phenylketonuria. Mol Genet Metab. 2013 Jan;108(1):13-7. PubMed PMID: 23177662

Brandao LN, Winges A, Christoph S, Sather S, Migdall-Wilson J, Schlegel J, McGranahan A, Gao D, Liang X, Deryckere D, Graham DK. Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia. Blood Cancer J. 2013 Jan 25;3:e101. PubMed PMID: 23353780

Prager JD, Ruiz AG, Mooney K, Gao D, Szolnoki J, Shah RK. Improving Operative Flow During Pediatric Airway Evaluation: A Quality-Improvement Initiative. JAMA Otolaryngol Head Neck Surg. 2014 Dec 26. [Epub ahead of print] PubMed PMID: 25541680

Maria Teresa Bourlon, Dexiang Gao, Sara Trigero, Julia Elizabeth Clemons, Elaine Tat Lam, Thomas W. Flaig. Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma (mRCC).

Roby BB, Mattingly J, Jensen EL, Gao D, Chan KH. Treatment of Juvenile Recurrent Parotitis of Childhood: An Analysis of Effectiveness. JAMA Otolaryngol Head Neck Surg. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25474272

Lam ET, Wong MK, Agarwal N, Redman BG, Logan T, Gao D, Flaig TW, Lewis K, Poust J, Monk P, Jarkowski A, Sendilnathan A, Bolden M, Kuzel TM, Olencki T. Retrospective analysis of the safety and efficacy of high-dose interleukin-2 after prior tyrosine kinase inhibitor therapy in patients with advanced renal cell carcinoma. J Immunother. 2014 Sep;37(7):360-5. PubMed PMID: 25075565

Cheng Y, Gao D, Tong T. Bias and variance reduction in estimating the proportion of true-null hypotheses. Biostatistics. 2015 Jan;16(1):189-204. PubMed PMID: 24963010

Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE. FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies. Clin Cancer Res. 2014 Jun 15;20(12):3299-309. PubMed PMID: 24771645

Garg S, LaGreca J, St Hilaire T, Gao D, Glotzbecker M, Li Y, Smith JT, Flynn J. Wound complications of vertical expandable prosthetic titanium rib incisions. Spine (Phila Pa 1976). 2014 Jun 1;39(13):E777-81. PubMed PMID: 24732832

Jindal S, Gao D, Bell P, Albrektsen G, Edgerton SM, Ambrosone CB, Thor AD, Borges VF, Schedin P. Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling. Breast Cancer Res. 2014 Mar 28;16(2):R31. PubMed PMID: 24678808

Chan KH, Gao D, Fernandez PG, Kingdom TT, Kumpe DA. Juvenile nasopharyngeal angiofibroma: vascular determinates for operative complications and tumor recurrence. Laryngoscope. 2014 Mar;124(3):672-7. PubMed PMID: 23929652

Dexiang Gao, Gary K. Grunwald and Stanley Xu. Simple Approach to Sample Size Calculation for Count Data in Matched Cohort Studies. International Journal of Statistics in Medical Research, 2014, Vol. 3, No. 3, 321-330.

Merrick DT, Gao D, Miller YE, Keith RL, Baron AE, Feser WJ, Kennedy TC, Blatchford P, Braudrick S, Hirsch FR, Heasley LE, Bunn PA Jr, Franklin WA. PERSISTENCE OF BRONCHIAL DYSPLASIA IS ASSOCIATED WITH DEVELOPMENT OF INVASIVE SQUAMOUS CELL CARCINOMA. Cancer Prev Res (Phila). 2015 Nov 5. [Epub ahead of print] PubMed PMID: 26542061

Russell, T. D., Jindal, S., Agunbiade, S., Gao, D., Troxell, M., Borges, V. F., & Schedin, P. (2015). Myoepithelial Cell Differentiation Markers in Ductal Carcinoma in Situ Progression. The American journal of pathology, 185(11), 3076-3089.

Arganbright, J. M., Jensen, E. L., Mattingly, J., Gao, D., & Chan, K. H. (2015). Utility of Inferior Turbinoplasty for the Treatment of Nasal Obstruction in Children: A 10-Year Review. JAMA Otolaryngology–Head & Neck Surgery, 141(10), 901-904.

Chan, K. H., Gao, D., Bronsert, M., Chevallier, K. M., & Perkins, J. N. (2015). Pediatric facial fractures: demographic determinants influencing clinical outcomes. The Laryngoscope.

Roby, B. B., Mattingly, J., Jensen, E. L., Gao, D., & Chan, K. H. (2015). Treatment of juvenile recurrent parotitis of childhood: an analysis of effectiveness. JAMA otolaryngology--head & neck surgery, 141(2), 126-129.

Prager, J. D., Ruiz, A. G., Mooney, K., Gao, D., Szolnoki, J., & Shah, R. K. (2015). Improving Operative Flow During Pediatric Airway Evaluation A Quality-Improvement Initiative. JAMA otolaryngology--head & neck surgery, 141(3), 229-235.

Arcaroli JJ, Tai WM, McWilliams R, Bagby S, Blatchford PJ, Purkey A, Quackenbush KS, Song E, Pitts TM, Gao D, Lieu C, McManus M, Tan AC, Zheng X, Zhang Q, Ozeck M,olson P, Jiang Z, Kopetz S, Jimeno A, Keysar S, Eckhardt G, Messersmith WA. A NOTCH1 Gene Copy Number Gain is a Prognostic Indicator of Worse Survival and a Predictive Biomarker to a Notch1 Targeting Antibody in Colorectal Cancer. Accepted by International Journal of Cancer

Maria Teresa Bourlon, Dexiang Gao, Sara Trigero, Julia Elizabeth Clemons, Elaine Tat Lam, Thomas W. Flaig. Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma (mRCC). Poster Presentation to the Genitourinary Cancers Symposium. February 26-28, 2015

Kit Man Wong*, Dexiang Gao*, Heather McCoy, Amanda Brock, Rebecca W Powell, Cindy O’Bryant, D Ross Camidge, Lia Gore, Antonio Jimeno, Jennifer R Diamond, Wells A Messersmith, S Gail Eckhardt, Stephen Leong (*co-authors) Predicting Outcomes in Patients with Advanced Malignancies Treated on Phase 1 Clinical Trials Poster Presentation to ASCO annual meeting, Chicago, Illinois. May 29-June 2, 2015

Barbara Helfrich, David Raben, Dexiang Gao and Paul A. Bunn, Jr. Effects of eribulin and radiation on a panel of small cell lung cancer (SCLC) cell lines. Poster presentation to the IASLC for the upcoming meeting, Denver, Colorado. Sept 2015

Barbara A Helfrich, Jihye Kim, Dexiang Gao, Dan C Chan, Zhiyong Zhang, Aik-Choon Tan & Paul A Bunn Jr. The aurora kinase B inhibitor AZD1152-HQPA inhibitor in small cell lung cancer (SCLC) Oral presentation to the IASLC for the upcoming meeting, Denver, Colorado. Sept 2015

Noonan SA, , Berry L, Gao Dexiang, Lu X, Baron A, Chestnut P, Hart N, Merrick D, Doebele RC, Varella-Garcia M, Camidge DR. Defining the cMET positive population of non-small cell lung cancer (NSCLC) patients based on unique clinical and demographic features Poster presentation to the IASLC for the upcoming meeting, Denver, Colorado. Sept 2015

Teresa Bourlon, M., Gao, D., Trigero, S., Elizabeth Clemons, J., Lam, E. T., & Flaig, T. W. (2015, March). Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma. In JOURNAL OF CLINICAL ONCOLOGY (Vol. 33, No. 7). 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA: AMER SOC CLINICAL ONCOLOGY.

Bowles DW, Keysar SB, Eagles, JR, Wang G, Glogowska MJ, McDermott JD, Le PD, Gao D,Ray CE, Rochon PJ, Roop DR,Tan AC,Serracino HS, Antonio Jimeno A. A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma Oral Oncology. Accepted by Oral Cancer

Yu H, Batenchuk C, Badzio A, Boyle TA, Czapiewski P, Chan DC, Lu X, Gao D, Ellison K, Kowalewski AA, Rivard CJ, Dziadziuszko R, Zhou C, Hussein M, Richards D, Wilks S, Monte M, Edenfield W, Goldschmidt J, Page R, Ulrich B, Waterhouse D, Close S, Jassem J, Kulig K, Hirsch FR. PD-L1 Expression by Two Complementary Diagnostic Assays and mRNA In Situ Hybridization in Small Cell Lung Cancer. J Thorac Oncol. 2016 Sep 14. [Epub ahead of print] PubMed PMID: 27639678

Bourlon MT, Gao D, Trigero S, Clemons JE, Breaker K, Lam ET, Flaig TW. Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma. Cancer Med. 2016 Oct 19. [Epub ahead of print] PubMed PMID: 27758076

Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 Jan;109(1). PubMed PMID: 27634934

Schade H, Sen S, Neff CP, Freed BM, Gao D, Gutman JA, Palmer BE. Programmed Death 1 Expression on CD4( ) T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 Dec;22(12):2172-2179. PubMed PMID: 27519280

Helfrich BA, Kim J, Gao D, Chan DC, Zhang Z, Tan AC, Bunn PA Jr. Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo. Mol Cancer Ther. 2016 Oct;15(10):2314-2322. PubMed PMID: 27496133

Noonan SA, Berry L, Lu X, Gao D, Barón AE, Chesnut P, Sheren J, Aisner DL, Merrick D, Doebele RC, Varella-Garcia M, Camidge DR. Identifying the Appropriate FISH Criteria for Defining MET Copy Number-Driven Lung Adenocarcinoma through Oncogene Overlap Analysis. J Thorac Oncol. 2016 Aug;11(8):1293-304. PubMed PMID: 27262212

Quackenbush KS, Bagby S, Tai WM, Messersmith WA, Schreiber A, Greene J, Kim J, Wang G, Purkey A, Pitts TM, Nguyen A, Gao D, Blatchford P, Capasso A, Schuller AG, Eckhardt SG, Arcaroli JJ. The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Oncotarget. 2016 May 10;7(19):28273-85. PubMed PMID: 27070088

Bowles DW, Keysar SB, Eagles JR, Wang G, Glogowska MJ, McDermott JD, Le PN, Gao D, Ray CE, Rochon PJ, Roop DR, Tan AC, Serracino HS, Jimeno A. A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma. Oral Oncol. 2016 Feb;53:74-9. PubMed PMID: 26705064

Merrick DT, Gao D, Miller YE, Keith RL, Baron AE, Feser W, Kennedy TC, Blatchford PJ, Braudrick S, Hirsch FR, Heasley L, Bunn PA Jr, Franklin WA. Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma. Cancer Prev Res (Phila). 2016 Jan;9(1):96-104. PubMed PMID: 26542061

Chan KH, Gao D, Bronsert M, Chevallier KM, Perkins JN. Pediatric facial fractures: Demographic determinants influencing clinical outcomes. Laryngoscope. 2016 Feb;126(2):485-90. PubMed PMID: 26199204

Arcaroli JJ, Tai WM, McWilliams R, Bagby S, Blatchford PJ, Varella-Garcia M, Purkey A, Quackenbush KS, Song EK, Pitts TM, Gao D, Lieu C, McManus M, Tan AC, Zheng X, Zhang Q, Ozeck M, Olson P, Jiang ZQ, Kopetz S, Jimeno A, Keysar S, Eckhardt G, Messersmith WA. A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer. Int J Cancer. 2016 Jan 1;138(1):195-205. PubMed PMID: 26152787

Abstract ID: ASPO20170328 Title: Evaluation of a Novel Method for Measuring Personality among Otolaryngology Residents Authors: Jeremy. D. Prager,Amanda. G. Ruiz, Liana. Puscas,Christine. Franzese,Dexiang Gao, Charles. Myer,Amy. Dimachkieh,Jeremy. D. Prager

Immune Checkpoints Expression in Small- Cell Lung Cancer Lines Hui Yu, Yayi He, Christopher J.Rivard, Dexiang Gao, Kim Ellison, Leslie Rozeboom, Kenichi Suda, Fred R. Hirsch

Friedman NR, Ruiz AG, Gao D, Ingram DG. Accuracy of Parental Perception of Nighttime Breathing in Children with Down Syndrome. Otolaryngol Head Neck Surg. 2017 Sep 1;:194599817726286. [Epub ahead of print] PubMed PMID: 28871845

Noonan SA, Patil T, Gao D, King GG, Thibault JR, Lu X, Bunn PA, Doebele RC, Purcell WT, Barón AE, Camidge DR. Baseline and On-Treatment Characteristics of Serum Tumor Markers in Stage IV Oncogene-Addicted Adenocarcinoma of the Lung. J Thorac Oncol. 2017 Aug 24. [Epub ahead of print] PubMed PMID: 28843358

Ingram DG, Ruiz AG, Gao D, Friedman NR. Success of Tonsillectomy for Obstructive Sleep Apnea in Children With Down Syndrome. J Clin Sleep Med. 2017 Aug 15;13(8):975-980. PubMed PMID: 28728615

Jordan KR, Kapoor P, Spongberg E, Tobin RP, Gao D, Borges VF, McCarter MD. Immunosuppressive myeloid-derived suppressor cells are increased in splenocytes from cancer patients. Cancer Immunol Immunother. 2017 Apr;66(4):503-513. PubMed PMID: 28108766

Chan KH, Gao D, Jensen EL, Allen GC, Cass SP. Complications and parent satisfaction in pediatric osseointegrated bone-conduction hearing implants. Laryngoscope. 2017 Sep;127(9):2165-2170. PubMed PMID: 28092097

Yu H, Batenchuk C, Badzio A, Boyle TA, Czapiewski P, Chan DC, Lu X, Gao D, Ellison K, Kowalewski AA, Rivard CJ, Dziadziuszko R, Zhou C, Hussein M, Richards D, Wilks S, Monte M, Edenfield W, Goldschmidt J, Page R, Ulrich B, Waterhouse D, Close S, Jassem J, Kulig K, Hirsch FR. PD-L1 Expression by Two Complementary Diagnostic Assays and mRNA In Situ Hybridization in Small Cell Lung Cancer. J Thorac Oncol. 2017 Jan;12(1):110-120. PubMed PMID: 27639678

Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 Jan;109(1). PubMed PMID: 27634934

Caroline Elizabeth McCoach, Dan Merrick, Dara L. Aisner, Paul A. Bunn, D. Ross Camidge, Dexiang Gao, Kimi Kondo, and Robert Charles Doebele. Early rebiopsy to identify mechanisms and biomarkers of tumor cell survival following epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapy. Journal of Clinical Oncology 2017 35:15_suppl, TPS9100-TPS9100

KH Chan, EL. Jensen, D Gao. Pediatric Tinnitus: A Clinical Perspective. The Laryngoscope

Kessler ER, Gao D, Flaig TW, Breaker K, Wold M, Wacker M, Lam ET. Phase II study of cabazitaxel with or without abiraterone acetate and prednisone in patients with metastatic castrate resistant prostate cancer after prior docetaxel and abiraterone acetate. Ann Oncol. 2017 Feb 14. doi: 10.1093/annonc/mdw674. [Epub ahead of print] PMID: 28203770

JR Diamond, SG Eckhardt, TM Pitts, AV Bokhoven, D Aisner, D Gustafson, A Capasso, AD Elias, AM Storniolo, BP Schneider, D Gao, JJ Tentler, VF Borges, KD Miller. Clinical safety and efficacy of the Aurora and angiogenic kinase inhibitor ENMD-2076 in previously treated, locally advanced or metastatic triple-negative breast cancer. SABCS 2017 Symposium

Mark JA, Campbell K, Gao D, Kramer RE. Algorithm to Predict Which Children With Chronic Abdominal Pain Are Low Suspicion for Significant Endoscopic Findings. Clin Pediatr (Phila). 2018 Oct 11;:9922818806317. [Epub ahead of print] PubMed PMID: 30306797

Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2018 Sep 7. [Epub ahead of print] PubMed PMID: 30297175

Kessler ER, Su LJ, Gao D, Torkko KC, Wacker M, Anduha M, Chronister N, Maroni P, Crawford ED, Flaig TW, Glode LM, Lam ET. Phase II Trial of Acai Juice Product in Biochemically Recurrent Prostate Cancer. Integr Cancer Ther. 2018 Oct 5;:1534735418803755. [Epub ahead of print] PubMed PMID: 30289005

Scholes MA, Jensen EL, Polaner DM, Gao D. Multiple surgeries in pediatric otolaryngology patients and associated anesthesia risks. Int J Pediatr Otorhinolaryngol. 2018 Oct;113:115-118. PubMed PMID: 30173968

Ren S, Rivard CJ, Yu H, Genova C, Rozenboom L, Gao D, Hinz TK, Rikke BA, Wynes MW, Caldwell C, Agustoni F, Kenichi Suda, Jiang T, Zhou C, Heasley LE, Hirsch FR. A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines. Clin Lung Cancer. 2018 Sep;19(5):450-456. PubMed PMID: 30146263

Morton JJ, Keysar SB, Perrenoud L, Chimed TS, Reisinger J, Jackson B, Le PN, Nieto C, Gomez K, Miller B, Gao D, Somerset H, Wang XJ, Jimeno A. Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer. Mol Carcinog. 2018 Nov;57(11):1651-1663. PubMed PMID: 30129680

Chan KH, Allen GC, Kelley PE, Streubel SO, Friedman NR, Yoon P, Gao D, Ruiz AG, Jung TTK. Dornase Alfa Ototoxic Effects in Animals and Efficacy in the Treatment of Clogged Tympanostomy Tubes in Children: A Preclinical Study and a Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2018 Sep 1;144(9):776-780. PubMed PMID: 30073253

Diamond JR, Eckhardt SG, Pitts TM, van Bokhoven A, Aisner D, Gustafson DL, Capasso A, Sams S, Kabos P, Zolman K, Colvin T, Elias AD, Storniolo AM, Schneider BP, Gao D, Tentler JJ, Borges VF, Miller KD. A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer. Breast Cancer Res. 2018 Aug 2;20(1):82. PubMed PMID: 30071865

Cao Y, Green K, Quattlebaum S, Milam B, Lu L, Gao D, He H, Li N, Gao L, Hall F, Whinery M, Handley E, Ma Y, Xu T, Jin F, Xiao J, Wei M, Smith D, Bornstein S, Gross N, Pyeon D, Song J, Lu SL. Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma. Clin Epigenetics. 2018;10:43. PubMed PMID: 29636832

Helfrich BA, Gao D, Bunn PA Jr. Eribulin inhibits the growth of small cell lung cancer cell lines alone and with radiotherapy. Lung Cancer. 2018 Apr;118:148-154. PubMed PMID: 29571994

Chan KH, Jensen EL, Gao D. Pediatric tinnitus: A clinical perspective. Laryngoscope. 2018 Mar;128(3):727-731. PubMed PMID: 29105770

Friedman NR, Ruiz AG, Gao D, Ingram DG. Accuracy of Parental Perception of Nighttime Breathing in Children with Down Syndrome. Otolaryngol Head Neck Surg. 2018 Feb;158(2):364-367. PubMed PMID: 28871845

Noonan SA, Patil T, Gao D, King GG, Thibault JR, Lu X, Bunn PA, Doebele RC, Purcell WT, Barón AE, Camidge DR. Baseline and On-Treatment Characteristics of Serum Tumor Markers in Stage IV Oncogene-Addicted Adenocarcinoma of the Lung. J Thorac Oncol. 2018 Jan;13(1):134-138. PubMed PMID: 28843358

Hui Yu, Camilla Koczara, Andrzej Badzio, Zoltan Lohinai, Balazs Dome, Judit Moldvay, Janos Fillinger, Dexiang Gao, Christopher Rivard, Kim Ellison, Kenichi Suda, Shengxiang Ren, Charles Caldwell, Kristine A. Brovsky, Leslie Rozeboom, Fred R. Hirsch. Expression and Significance of PVR-TIGIT/CD226, An Immune Checkpoint Axis in Small Cell Lung cancer. Poster presentation 2018 WCLC

Terry L. Ng, Hui Yu, Derek Smith, Theresa A. Boyle, Emily R. York, Scott Leedy, Dexiang Gao, Lynn Heasley, Fred R. Hirsch, D. Ross Camidge. Preselection of lung cancer cases using FGFR1 mRNA and gene copy number for treatment with ponatinib. Poster presentation 2018 ASCO Annual Meeting

Mark JA, Campbell K, Gao D, Kramer REALGORITHM TO PREDICT WHICH CHILDREN WITH CHRONIC ABDOMINAL PAIN ARE UNLIKELY TO BENEFIT FROM ENDOSCOPY Poster presentation to DDW 2018

Samson JM, Ravindran Menon D, Smith DE, Baird E, Kitano T, Gao D, Tan AC, Fujita M. Clinical implications of ALDH1A1 and ALDH1A3 mRNA expression in melanoma subtypes. Chem Biol Interact. 2019 Dec 1;314:108822. PubMed PMID: 31580832

Pacheco JM, Gao D, Camidge DR. Extended follow-up on KEYNOTE-024 suggests significant survival benefit for pembrolizumab in patients with PD-L1 =50%, but unanswered questions remain. Ann Transl Med. 2019 Jul;7(Suppl 3):S127. PubMed PMID: 31576334

Greenlee CJ, Scholes MA, Gao D, Friedman NR. Obstructive Sleep Apnea and Sleep Position: Does It Matter for Infants With a Cleft Palate?. Cleft Palate Craniofac J. 2019 Aug;56(7):890-895. PubMed PMID: 31282194

Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. How many lymph nodes are enough? Assessing the adequacy of lymph node yield for staging in favorable histology wilms tumor. J Pediatr Surg. 2019 Nov;54(11):2331-2335. PubMed PMID: 31255328

Osborne DG, Domenico J, Luo Y, Reid AL, Amato C, Zhai Z, Gao D, Ziman M, Dinarello CA, Robinson WA, Fujita M. Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome. Mol Carcinog. 2019 Sep;58(9):1670-1679. PubMed PMID: 31099111

Ruiz AG, Gao D, Ingram DG, Hickey F, Haemer MA, Friedman NR. Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?. J Pediatr. 2019 Aug;211:179-184.e1. PubMed PMID: 31084917

Friedman NR, Ruiz AG, Gao D, Jensen A, Mitchell RB. Pediatric Obstructive Sleep-Disordered Breathing: Updated Polysomnography Practice Patterns. Otolaryngol Head Neck Surg. 2019 Sep;161(3):529-535. PubMed PMID: 31035864

Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J. Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC. Mol Cancer Res. 2019 Jun;17(6):1351-1364. PubMed PMID: 30808730

Pacheco JM, Gao D, Smith D, Purcell T, Hancock M, Bunn P, Robin T, Liu A, Karam S, Gaspar L, Kavanagh B, Rusthoven C, Aisner D, Doebele R, Camidge DR. Natural History and Factors Associated with Overall Survival in Stage IV ALK-Rearranged Non-Small Cell Lung Cancer. J Thorac Oncol. 2019 Apr;14(4):691-700. PubMed PMID: 30599201

Ng TL, Smith DE, Mushtaq R, Patil T, Dimou A, Yang S, Liu Q, Li X, Zhou C, Jones RT, Tu MM, Yan F, Bowman IA, Liu SV, Newkirk S, Bauml J, Doebele RC, Aisner DL, Gao D, Ren S, Camidge DR. ROS1 Gene Rearrangements Are Associated With an Elevated Risk of Peridiagnosis Thromboembolic Events. J Thorac Oncol. 2019 Apr;14(4):596-605. PubMed PMID: 30543838

Mark JA, Campbell K, Gao D, Kramer RE. Algorithm to Predict Which Children With Chronic Abdominal Pain Are Low Suspicion for Significant Endoscopic Findings. Clin Pediatr (Phila). 2019 Jan;58(1):79-87. PubMed PMID: 30306797

Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2019 Jan;20(1):e39-e51. PubMed PMID: 30297175

Tucatinib, palbociclib and letrozole in HR+/HER2+ metastatic breast cancer: report of phase IB safety cohort Elena Shagisultanova, Pavani Chalasani, Ursa Brown-Glaberman, William J. Gradishar, Andrew Brenner, Alison Stopeck, Dexiang Gao, Tessa McSpadden, Peter Kabos, Virginia F. Borges1

Kagihara JA, Weiss JA, Nicklawsky A, Gao D, Borges VF, Kabos P, Jimeno A, Diamond JR. Efficacy of Immunotherapy Agents in Patients with Metastatic Breast Cancer Treated in Phase I Clinical Trials.

Adrenal metastases in malignant melanoma, is it a privileged site? Rao Mushtaq, Dexiang Gao,...

Pilot study to enhance FDG-PET imaging of prostate cancers with the metabolic inhibitor ranolazine. Isabel Schlaepfer,... Dexiang Gao,...

Higgins M, Smith DE, Gao D, Wilcox D, Cost NG, Saltzman AF. The impact of age at orchiopexy on testicular cancer outcomes. World J Urol. 2019 Nov 28. [Epub ahead of print] PubMed PMID: 31781896

Tobin RP, Jordan KR, Kapoor P, Spongberg E, Davis D, Vorwald VM, Couts KL, Gao D, Smith DE, Borgers JSW, Robinson S, Amato C, Gonzalez R, Lewis KD, Robinson WA, Borges VF, McCarter MD. IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients. Front Oncol. 2019;9:1223. PubMed PMID: 31781510

Borges VF, Hu J, Young C, Maggard J, Parris HJ, Gao D, Lyons TR. Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ Breast Cancer. 2020;6:56. PubMed PMID: 33088913

Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft. Mol Cancer Res. 2020 Oct 21. [Epub ahead of print] PubMed PMID: 33087417

Boxley PJ, Smith DE, Gao D, Kessler ER, Echalier B, Bernard B, Ormond DR, Lam ET, Kavanagh BD, Flaig TW. Prostate Cancer Central Nervous System Metastasis in a Contemporary Cohort. Clin Genitourin Cancer. 2020 Aug 22. [Epub ahead of print] PubMed PMID: 33069585

Weiss JA, Nicklawsky A, Kagihara JA, Gao D, Fisher C, Elias A, Borges VF, Kabos P, Davis SL, Leong S, Eckhardt SG, Diamond JR. Clinical outcomes of breast cancer patients treated in phase I clinical trials at University of Colorado Cancer Center. Cancer Med. 2020 Oct 16. [Epub ahead of print] PubMed PMID: 33063469

Chen SMY, Li B, Nicklawsky AG, Krinsky AL, Brunetti T, Woolaver RA, Wang X, Chen Z, Young CD, Gao D, Wang XJ, Wang JH. Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15( ) Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma. Int J Mol Sci. 2020 Sep 9;21(18). PubMed PMID: 32916850

Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. Reply to Letter to the Editor. J Pediatr Surg. 2020 Jun 25. [Epub ahead of print] PubMed PMID: 32684283

Rusthoven CG, Yamamoto M, Bernhardt D, Smith DE, Gao D, Serizawa T, Yomo S, Aiyama H, Higuchi Y, Shuto T, Akabane A, Sato Y, Niranjan A, Faramand AM, Lunsford LD, McInerney J, Tuanquin LC, Zacharia BE, Chiang V, Singh C, Yu JB, Braunstein S, Mathieu D, Touchette CJ, Lee CC, Yang HC, Aizer AA, Cagney DN, Chan MD, Kondziolka D, Bernstein K, Silverman JS, Grills IS, Siddiqui ZA, Yuan JC, Sheehan JP, Cordeiro D, Nosaki K, Seto T, Deibert CP, Verma V, Day S, Halasz LM, Warnick RE, Trifiletti DM, Palmer JD, Attia A, Li B, Cifarelli CP, Brown PD, Vargo JA, Combs SE, Kessel KA, Rieken S, Patel S, Guckenberger M, Andratschke N, Kavanagh BD, Robin TP. Evaluation of First-line Radiosurgery vs Whole-Brain Radiotherapy for Small Cell Lung Cancer Brain Metastases: The FIRE-SCLC Cohort Study. JAMA Oncol. 2020 Jul 1;6(7):1028-1037. PubMed PMID: 32496550

Saltzman AF, Smith DE, Gao D, Cost NG. Lymph node yield in pediatric, adolescent and young adult Renal Cell Carcinoma - How many are enough?. J Pediatr Surg. 2020 Apr 17. [Epub ahead of print] PubMed PMID: 32409174

Simons EA, Smith DE, Gao D, Camidge DR. Variation in Toxicity Reporting Methods for Early Phase Lung Cancer Treatment Trials at Oncology Conferences. J Thorac Oncol. 2020 Sep;15(9):1425-1433. PubMed PMID: 32353598

Higgins M, Smith DE, Gao D, Wilcox D, Cost NG, Saltzman AF. The impact of age at orchiopexy on testicular cancer outcomes. World J Urol. 2020 Oct;38(10):2531-2536. PubMed PMID: 31781896

A Kagihara, JA Weiss, A Nicklawsky, D Gao… - 2020 - AACR Abstract A76: Efficacy of immunotherapy agents in patients with metastatic breast cancer treated in phase I clinical trials

Paul Maroni, Elizabeth R. Kessler, Rodrigo Rodrigues-Pessoa, Andrew Nicklawsky, Thomas Flaig, Elaine Lam, Brandon Bernard, James Moore, Kyra Anderson, Dexiang Gao, Komal Raina and Rajesh Agarwal. Abstract CT207: A phase II trial using grape seed extract for prostate cancer patients with non-metastatic PSA progression after local therapy. Cancer Research

Ling Lv, Steve Quattlebaum, Dexiang Gao, Yu Cao, Ben Milam, Francis Hall, Derek Smith, Elyse Handley, Sophia Bornstein, Neil Gross, John Song and Shi-Long Lu. Abstract B07: Potential clinical value of methylated microRNAs in saliva-liquid biopsy for surveillance of head and neck squamous cell carcinoma. Clinical Cancer Research

Elias, Anthony; Spoelstra, Nicole; Vidal, Gregory A; Sams, Sharon B; ... Gao, Dexiang Phase II trial of fulvestrant plus enzalutamide in ER+/Her2- advanced breast cancer 2020 San Antonio Breast Cancer Symposium December 8-12, 2020

Elias, Anthony; Fornier, Monica; Vidal, Gregory A; Sams, Sharon B;...Gao, Dexiang... Phase II randomized trial of fulvestrant with or without enzalutamide in ER+/Her2- primary breast cancer (BC) oster presentation at the 2020 San Antonio Breast Cancer Symposium®, December 8-12, 2020.

Hecht SL, Quach A, Gao D, Brazell A, Beltran G, Holbrook S, Gore L, Iguchi N, Malykhina A, Wilcox D, Cost NG. A prospective survey study of lower urinary tract dysfunction in childhood cancer survivors after vincristine and/or doxorubicin chemotherapy. Pediatr Blood Cancer. 2021 Oct;68(10):e29226. PubMed PMID: 34245214

Jackson CL, Colborn K, Gao D, Rao S, Slater HC, Parikh S, Foy BD, Kittelson J. Design and analysis of a 2-year parallel follow-up of repeated ivermectin mass drug administrations for control of malaria: Small sample considerations for cluster-randomized trials with count data. Clin Trials. 2021 Oct;18(5):582-593. PubMed PMID: 34218684

Kolb JM, Hu J, DeSanto K, Gao D, Singh S, Imperiale T, Lieberman DA, Boland CR, Patel SG. Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis. Gastroenterology. 2021 Oct;161(4):1145-1155.e12. PubMed PMID: 34119517

Schreiber AR, Kagihara JA, Weiss JA, Nicklawsky A, Gao D, Borges VF, Kabos P, Diamond JR. Clinical Outcomes for Patients With Metastatic Breast Cancer Treated With Immunotherapy Agents in Phase I Clinical Trials. Front Oncol. 2021;11:640690. PubMed PMID: 33816286

Shay R, Nicklawsky A, Gao D, Lam ET. A Cost-Effectiveness Analysis of Nivolumab Plus Ipilimumab Versus Pembrolizumab Plus Axitinib and Versus Avelumab Plus Axitinib in First-Line Treatment of Advanced Renal Cell Carcinoma. Clin Genitourin Cancer. 2021 Aug;19(4):370-370.e7. PubMed PMID: 33674224

Qi Z, Qiu Y, Wang Z, Zhang H, Lu L, Liu Y, Mathes D, Pomfret EA, Gao D, Lu SL, Wang Z. A novel diphtheria toxin-based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma. Mol Oncol. 2021 Apr;15(4):1054-1068. PubMed PMID: 33540470

Patel SG, Hampel H, Smith D, Gao D, Cockburn M, Kastrinos F. Advanced adenomas may be a red flag for hereditary cancer syndromes. Hered Cancer Clin Pract. 2021 Jan 12;19(1):8. PubMed PMID: 33436027

Woolaver RA, Wang X, Krinsky AL, Waschke BC, Chen SMY, Popolizio V, Nicklawsky AG, Gao D, Chen Z, Jimeno A, Wang XJ, Wang JH. Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts. J Immunother Cancer. 2021 Jan;9(1). PubMed PMID: 33414263

Borges VF, Hu J, Young C, Maggard J, Parris HJ, Gao D, Lyons TR. Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ Breast Cancer. 2020;6:56. PubMed PMID: 33088913

Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft. Mol Cancer Res. 2021 Feb;19(2):346-357. PubMed PMID: 33087417

Vinogradskiy Y, Castillo R, Castillo E, Schubert L, Jones BL, Faught A, Gaspar LE, Kwak J, Bowles DW, Waxweiler T, Dougherty JM, Gao D, Stevens C, Miften M, Kavanagh B, Grills I, Rusthoven CG, Guerrero T. Results of a multi-institutional phase II clinical trial for 4DCT-ventilation functional avoidance thoracic radiotherapy. Int J Radiat Oncol Biol Phys. 2021 Nov 9. [Epub ahead of print] PubMed PMID: 34767934

Boxley PJ, Smith DE, Gao D, Kessler ER, Echalier B, Bernard B, Ormond DR, Lam ET, Kavanagh BD, Flaig TW. Prostate Cancer Central Nervous System Metastasis in a Contemporary Cohort. Clin Genitourin Cancer. 2021 Jun;19(3):217-222.e1. PubMed PMID: 33069585

Weiss JA, Nicklawsky A, Kagihara JA, Gao D, Fisher C, Elias A, Borges VF, Kabos P, Davis SL, Leong S, Eckhardt SG, Diamond JR. Clinical outcomes of breast cancer patients treated in phase I clinical trials at University of Colorado Cancer Center. Cancer Med. 2020 Dec;9(23):8801-8808. PubMed PMID: 33063469

Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. Reply to Letter to the Editor. J Pediatr Surg. 2020 Nov;55(11):2537-2538. PubMed PMID: 32684283

Bang TJ, Hu J, Patil T, Barón AE, Gao D, Yang JC, Kuo HY, Huang HC, Sachs PB, Camidge DR. The Effect of Intrathoracic Lesion Location on Initial Tyrosine Kinase Inhibitor Response in Advanced Oncogene-Addicted Non-Small Cell Lung Cancer: A Comparison Between RECIST 1.1 and a Novel Method of Response Assessment (MAX). Clin Lung Cancer. 2022 Aug 7. [Epub ahead of print] PubMed PMID: 36100512

Batta N, Shangraw S, Nicklawsky A, Yamauchi T, Zhai Z, Menon DR, Gao D, Dellavalle RP, Fujita M. Global melanoma correlations with obesity, smoking, and alcohol consumption. JMIR Dermatol. 2021 Jul-Dec;4(2). PubMed PMID: 35990801

Tsui DCC, Drusbosky LM, Wienke S, Gao D, Bubie A, Barbacioru C, Camidge DR. Oncogene Overlap Analysis of Circulating Cell-free Tumor DNA to Explore the Appropriate Criteria for Defining MET Copy Number-Driven Lung Cancer. Clin Lung Cancer. 2022 Nov;23(7):630-638. PubMed PMID: 35961935

Muething L, Quach B, Smith DE, Gao D, Smith JA, Simril RT 3rd, Tompkins A, Espinoza J, Cowan ML, Hammad H, Wani S, Patel SG. Adoption of Optimal Small (6-9 mm) Colorectal Polyp Resection Technique Over Time. Dig Dis Sci. 2022 May 27. [Epub ahead of print] PubMed PMID: 35624328

Shiao JC, Holt D, Ladbury C, Gao D, Jones B, Karam SD, Amini A. The role of concomitant chemoradiotherapy versus radiation alone in T1-3N0 HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma. Oral Oncol. 2022 Jul;130:105907. PubMed PMID: 35605559

Shagisultanova E, Gao D, Callihan E, Parris HJ, Risendal B, Hines LM, Slattery ML, Baumgartner K, Schedin P, John EM, Borges VF. Overall survival is the lowest among young women with postpartum breast cancer. Eur J Cancer. 2022 Jun;168:119-127. PubMed PMID: 35525161

Chen SMY, Popolizio V, Woolaver RA, Ge H, Krinsky AL, John J, Danis E, Ke Y, Kramer Y, Bian L, Nicklawsky AG, Gao D, Liu S, Chen Z, Wang XJ, Wang JH. Differential responses to immune checkpoint inhibitor dictated by pre-existing differential immune profiles in squamous cell carcinomas caused by same initial oncogenic drivers. J Exp Clin Cancer Res. 2022 Apr 2;41(1):123. PubMed PMID: 35366939

Gao D, Hu J, Bradley CJ, Yang F. Instrumental variable analysis for cost outcome: Application to the effect of primary care visit on medical cost among low-income adults. Stat Med. 2023 Oct 30;42(24):4349-4376. PubMed PMID: 37828812

Iguchi N, Hecht SL, Gao D, Wilcox DT, Malykhina AP, Cost NG. Sexual dimorphic impacts of systemic vincristine on lower urinary tract function. Sci Rep. 2022 Mar 24;12(1):5113. PubMed PMID: 35332157

Hu J, Alami V, Zhuang Y, Alzofon N, Jimeno A, Gao D. Integrated variant allele frequency analysis pipeline and R package: easyVAF. Mol Carcinog. 2023 Dec;62(12):1877-1887. PubMed PMID: 37606183

Nieto C, Miller B, Alzofon N, Chimed T, Himes J, Joshi M, Gomez K, Chowdhury FN, Le PN, Weaver A, Somerset H, Morton JJ, Wang JH, Wang XJ, Gao D, Hansen K, Keysar SB, Jimeno A. The programmed death ligand 1 interactome demonstrates bidirectional signaling coordinating immune suppression and cancer progression in head and neck squamous cell carcinoma. J Natl Cancer Inst. 2023 Nov 8;115(11):1392-1403. PubMed PMID: 37389416

Shagisultanova E, Gradishar W, Brown-Glabberman U, Chalasani P, Brenner AJ, Stopeck A, Parris H, Gao D, Mcspadden T, Mayordomo J, Diamond JR, Kabos P, Borges VF. Safety and efficacy of tucatinib, letrozole and palbociclib in patients with previously treated HR /HER2 breast cancer. Clin Cancer Res. 2023 Jun 26. [Epub ahead of print] PubMed PMID: 37363965

Shiao JC, Santoso A, Stuhr K, Bennett SJ, Gao D, Holt DE, Robin T, Fisher CM. Gynecologic interstitial brachytherapy curriculum using a low-cost phantom with ultrasound workshop and a treatment planning workshop is effective. Brachytherapy. 2022 Jan-Feb;21(1):110-119. PubMed PMID: 34876360

Vinogradskiy Y, Castillo R, Castillo E, Schubert L, Jones BL, Faught A, Gaspar LE, Kwak J, Bowles DW, Waxweiler T, Dougherty JM, Gao D, Stevens C, Miften M, Kavanagh B, Grills I, Rusthoven CG, Guerrero T. Results of a Multi-Institutional Phase 2 Clinical Trial for 4DCT-Ventilation Functional Avoidance Thoracic Radiation Therapy. Int J Radiat Oncol Biol Phys. 2022 Mar 15;112(4):986-995. PubMed PMID: 34767934

Targeting MDSC differentiation using ATRA: a phase I/II clinical trial combining pembrolizumab and all-trans retinoic acid for metastatic melanoma Richard P. Tobin, Dasha T. Cogswell, Victoria M. Cates, Dana M. Davis, Jessica S.W. Borgers, Robert J. Van Gulick, Elizabeth Katsnelson1, Kasey L. Couts, Kimberly R. Jordan, Dexiang Gao, Eduardo Davila, Theresa M. Medina, Karl D. Lewis, Rene Gonzalez, Ross W. McFarland, William A. Robinson, and Martin D. McCarter

Jennifer K. Richer, Nicole S. Spoelstra, Alyse Winchester, Julia Wulfkuhle, Sharon B. Sams, Gregory Vidal, Peter Kabos, Jennifer Diamond, Elena Shagisultanova, Anosheh Afghahi, Jose Mayordomo, Tessa McSpadden, Gloria Crawford, Virginia Borges, Dexiang Gao, Emanuel Petricoin, Anthony D. Elias. Laboratory analyses of metastatic ER+/Her2- breast cancer treated with fulvestrant plus enzalutamide [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 2867.

AR. Schreiber, J Kagihara, A. Nicklawsky, D. Gao, A. Afghahi, A. Elias, P. Kabos, E. Shagisultanova, T. Pitts, J Lang, S. Karam, ... A Phase II Study Evaluating the Combination of Radiotherapy with Chemotherapy and Pembrolizumab in Patientswith PD-L1-Positive Metastatic Triple-Negative Breast Cancer. Abstract ID: 1307698 SABCS Dec 6-10, 2022

A. Elias, M Fornier, G. Vidal, EF Petricoin, K. Zolman, S. Biller, V. Alami, AW. Staley, T. McSpadden, VF. Borges, D. Gao, JF. Richer Randomized phase II trial of preoperative fulvestrant with or without enzalutamide forER+/Her2- breast cancer Abstract ID: 1310755 SABCS Dec 6-10, 2022

Chi C, Knight WE, Riching AS, Zhang Z, Tatavosian R, Zhuang Y, Moldovan R, Rachubinski AL, Gao D, Xu H, Espinosa JM, Song K. Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling. iScience. 2023 Jul 21;26(7):107012. PubMed PMID: 37360690

Donson AM, Bertrand KC, Riemondy KA, Gao D, Zhuang Y, Sanford B, Norris GA, Chapman RJ, Fu R, Willard N, Griesinger AM, Ribeiro de Sousa G, Amani V, Grimaldo E, Hankinson TC, Booker F, Sill M, Grundy RG, Pajtler KW, Ellison DW, Foreman NK, Ritzmann TA. Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study. Neuro Oncol. 2023 Oct 3;25(10):1854-1867. PubMed PMID: 37246777

Elias AD, Spoelstra NS, Staley AW, Sams S, Crump LS, Vidal GA, Borges VF, Kabos P, Diamond JR, Shagisultanova E, Afghahi A, Mayordomo J, McSpadden T, Crawford G, D'Alessandro A, Zolman KL, van Bokhoven A, Zhuang Y, Gallagher RI, Wulfkuhle JD, Petricoin Iii EF, Gao D, Richer JK. Phase II trial of fulvestrant plus enzalutamide in ER /HER2- advanced breast cancer. NPJ Breast Cancer. 2023 May 20;9(1):41. PubMed PMID: 37210417

Vaddi PK, Osborne DG, Nicklawsky A, Williams NK, Menon DR, Smith D, Mayer J, Reid A, Domenico J, Nguyen GH, Robinson WA, Ziman M, Gao D, Zhai Z, Fujita M. CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients. Front Immunol. 2023;14:1173035. PubMed PMID: 37197667

Wang Z, Ma J, Zhang H, Ramakrishna R, Mintzlaff D, Mathes DW, Pomfret EA, Lucia MS, Gao D, Haverkos BM, Wang Z. CCR4-IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T-cell lymphoma in a mouse CTCL model. FEBS Open Bio. 2023 Jul;13(7):1309-1319. PubMed PMID: 37157185

Rusthoven CG, Staley AW, Gao D, Yomo S, Bernhardt D, Wandrey N, El Shafie R, Kraemer A, Padilla O, Chiang V, Faramand AM, Palmer JD, Zacharia BE, Wegner RE, Hattangadi-Gluth JA, Levy A, Bernstein K, Mathieu D, Cagney DN, Chan MD, Grills IS, Braunstein S, Lee CC, Sheehan JP, Kluwe C, Patel S, Halasz LM, Andratschke N, Deibert CP, Verma V, Trifiletti DM, Cifarelli CP, Debus J, Combs SE, Sato Y, Higuchi Y, Aoyagi K, Brown PD, Alami V, Niranjan A, Lunsford LD, Kondziolka D, Camidge DR, Kavanagh BD, Robin TP, Serizawa T, Yamamoto M. Comparison of first-line radiosurgery for small-cell and non-small cell lung cancer brain metastases (CROSS-FIRE). J Natl Cancer Inst. 2023 Aug 8;115(8):926-936. PubMed PMID: 37142267

McLean-Thomas L, Gao D, Trenbeath Z, Cost CR, Milgrom SA. Equivocal end-of-therapy imaging findings do not predict a higher risk of local relapse after definitive radiotherapy in pediatric Ewing sarcoma and rhabdomyosarcoma. Pediatr Blood Cancer. 2023 May;70(5):e29989. PubMed PMID: 36726177

Wandrey NE, Gao D, Robin TP, Contessa JN, Singh C, Chiang V, Li J, Chen A, Wang Y, Sheehan JP, Dutta SW, Weiss SE, Paly J, Rusthoven CG. Multicenter analysis of stereotactic radiosurgery for multiple brain metastases from EGFR and ALK driven non-small cell lung cancer. Lung Cancer. 2023 Feb;176:144-148. PubMed PMID: 36641932

Tobin RP, Cogswell DT, Cates VM, Davis DM, Borgers JSW, Van Gulick RJ, Katsnelson E, Couts KL, Jordan KR, Gao D, Davila E, Medina TM, Lewis KD, Gonzalez R, McFarland RW, Robinson WA, McCarter MD. Targeting MDSC Differentiation Using ATRA: A Phase I/II Clinical Trial Combining Pembrolizumab and All-Trans Retinoic Acid for Metastatic Melanoma. Clin Cancer Res. 2023 Apr 3;29(7):1209-1219. PubMed PMID: 36378549

Bang TJ, Hu J, Patil T, Barón AE, Gao D, Yang JC, Kuo HY, Huang HC, Sachs PB, Camidge DR. The Effect of Intrathoracic Lesion Location on Initial Tyrosine Kinase Inhibitor Response in Advanced Oncogene-Addicted Non-Small Cell Lung Cancer: A Comparison Between RECIST 1.1 and a Novel Method of Response Assessment (MAX). Clin Lung Cancer. 2022 Dec;23(8):e501-e509. PubMed PMID: 36100512

Muething L, Quach B, Smith DE, Gao D, Smith JA, Simril RT 3rd, Tompkins A, Espinoza J, Cowan ML, Hammad H, Wani S, Patel SG. Adoption of Optimal Small (6-9 mm) Colorectal Polyp Resection Technique Over Time. Dig Dis Sci. 2023 Jan;68(1):240-251. PubMed PMID: 35624328

Elias AD, Staley A, Fornier M, Vidal GA, Sams S, Spoelstra N, Kabos P, Diamond JR, Shagisultanova E, Gallagher RI, Wulfkuhle J, Petricoin E, Zolman K, Biller S, Alami V, McSpadden T, Borges V, Crump LS, Gao D, Richer JK. Abstract CT144: Randomized phase II trial of preoperative fulvestrant with or without enzalutamide for ER+/Her2- breast cancer. Cancer Research [Internet]. 2023 Apr 14;83(8_Supplement):CT144–CT144. Available from: http://dx.doi.org/10.1158/1538-7445.AM2023-CT144

Elias AD, Staley AW, Fornier M, Vidal GA, Alami V, Sams S, Spoelstra NS, Goodspeed A, Kabos P, Diamond JR, Shagisultanova E, Gallagher RI, Wulfkuhle JD, Petricoin EF, Zolman KL, McSpadden T, Jordan KR, Slansky JE, Borges VF, Gao D, Richer JK. Clinical and immune responses to neoadjuvant fulvestrant with or without enzalutamide in ER /Her2- breast cancer. NPJ Breast Cancer. 2024 Oct 6;10(1):88. PubMed PMID: 39368973

Brooks T, Gao D, Dorris K, Boone K, Mirsky DM, Staulcup S, Prince E, Moskalenko M, Ignowski E, Wandrey N, Fakhoury K, Hankinson TC, Milgrom SA. Does pre-irradiation gross tumor volume predict the risk of progression after radiation therapy in pediatric patients with adamantinomatous craniopharyngioma?. J Neurosurg Pediatr. 2024 Sep 27;:1-7. [Epub ahead of print] PubMed PMID: 39332032

Qiu Y, Lu L, Halven A, Terrio R, Yuldelson S, Dougal N, Galbo F, Lu A, Gao D, Blomquist B, Zevallos JP, Lu SL, Yao X, Harry BL. Extraction-Free Testing for SARS-CoV-2 in Nasal Swab and Saliva Samples on a Single High-Throughput Platform. J Biotechnol Biomed. 2024;7(2):214-220. PubMed PMID: 39086601

Tsui DCC, Holt DE, Patil T, Staley A, Gao D, Kavanagh BD, Schenk EL, Rusthoven CG, Camidge DR. The Role of Local Therapy for Oligo-Progressive Disease in Oncogene-Addicted Non-Small-Cell Lung Cancer. Adv Radiat Oncol. 2024 Jul;9(7):101516. PubMed PMID: 38868503

Chia SB, Johnson BJ, Hu J, Vermeulen R, Chadeau-Hyam M, Guntoro F, Montgomery H, Boorgula MP, Sreekanth V, Goodspeed A, Davenport B, Pereira FV, Zaberezhnyy V, Schleicher WE, Gao D, Cadar AN, Papanicolaou M, Beheshti A, Baylin SB, Costello J, Bartley JM, Morrison TE, Aguirre-Ghiso JA, Rincon M, DeGregori J. Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungs. Res Sq. 2024 Apr 5. PubMed PMID: 38645169

Shiao JC, Gao D, Mueller A, Holt DE, Moskalenko M, Zaccone J, Waxweiler TV, Robin TP, Nath SK. Pilot Curriculum for Continued Professional Development of Radiation Oncology Nurses. Adv Radiat Oncol. 2024 Feb;9(2):101372. PubMed PMID: 38405320

Pembrolizumab and all-trans retinoic acid combination treatment of advanced melanoma: long-term survival update. Authors Jessica Borgers, Theresa Medina, William Robinson, Elizabeth Katnelson, Claire Muckle, Dexiang Gao, Richard Tobin, Martin McCarter submitted to Society of Immunotherapy for cancer, 2024 Huston

Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungs Shi B. Chia, ... Dexiang Gao ... submitted to AACR Tumor Body Interaction conference: The roles of micro- and macroenvironment in cancer in Boston. 2024

Integrated variant allele frequency analysis pipeline and R package: easyVAF. 10th World Congress on CANCER RESEARCH AND THERAPY June 20 - 22, 2024 at Prague, Czech Republic

Toxicity of Comprehensive hypofractionated radiation therapy for node positive breast caner: primary outcones of a phase II trial. CM Fisher, MW Jackson, D Gao, JW Ridings, JH Petit, and RA Rabinovitch. Submitted to Astro 2024

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