Robert Quaife, MD

Professional Titles

• Director, Advanced Cardiac Imaging

Recognitions

• Endowed Professorship, Advanced Cardiac Imaging and Image Guidance (2022)

Publications

• Magnetic Resonance Imaging Characterization and Clinical Outcomes of Dilated and Arrhythmogenic Left Ventricular Cardiomyopathies. Castrichini M, De Luca A, De Angelis G, Neves R, Paldino A, Dal Ferro M, Barbati G, Medo K, Barison A, Grigoratos C, Gigli M, Stolfo D, Brun F, Groves DW, Quaife R, Eldemire R, Graw S, Addison J, Todiere G, Gueli IA, Botto N, Emdin M, Aquaro GD, Garmany R, Pereira NL, Taylor MRG, Ackerman MJ, Sinagra G, Mestroni L, Giudicessi JR, Merlo M. J Am Coll Cardiol. 2024 May 14;83(19):1841-1851. doi: 10.1016/j.jacc.2024.02.041. PMID: 38719365
• Saxon CE, Genders TSS, Quaife RA, Chen SJ, Burke JM, McGuinn EM. Aortic valve chordae tendineae: A rare cause of aortic stenosis. Radiol Case Rep. 2023 Jan;18(1):1-3. PubMed PMID: 36312300
• Altman NL, Berning AA, Mann SC, Quaife RA, Gill EA, Auerbach SR, Campbell TB, Bristow MR. Vaccination-Associated Myocarditis and Myocardial Injury. Circ Res. 2023 May 12;132(10):1338-1357. PubMed PMID: 37167355
• Saxon CE, Genders TSS, Quaife RA, Chen SJ, Burke JM, McGuinn EM. Aortic valve chordae tendineae: A rare cause of aortic stenosis. Radiol Case Rep. 2023 Jan;18(1):1-3. PubMed PMID: 36312300
• Altman NL, Berning AA, Saxon CE, Adamek KE, Wagner JA, Slavov D, Quaife RA, Gill EA, Minobe WA, Jonas ER, Carroll IA, Huebler SP, Raines J, Messenger JC, Ambardekar AV, Mestroni L, Rosenberg RM, Rove J, Campbell TB, Bristow MR. Myocardial Injury and Altered Gene Expression Associated With SARS-CoV-2 Infection or mRNA Vaccination. JACC Basic Transl Sci. 2023 Feb;8(2):124-137. PubMed PMID: 36281440
• Shakowski C, Pham VA, Raines J, Quaife RA, Page RL 2nd. Safety and efficacy of IV theophylline for regadenoson-associated side effect reversal. J Nucl Cardiol. 2023 Apr;30(2):585-589. PubMed PMID: 35799037
• Altman NL, Berning AA, Saxon CE, Adamek KE, Wagner JA, Slavov D, Quaife RA, Gill EA, Minobe WA, Jonas ER, Carroll IA, Huebler SP, Raines J, Messenger JC, Ambardekar AV, Mestroni L, Rosenberg RM, Rove J, Campbell TB, Bristow MR. Myocardial Injury and Altered Gene Expression Associated With SARS-CoV-2 Infection or mRNA Vaccination. JACC Basic Transl Sci. 2022 Oct 19. [Epub ahead of print] PubMed PMID: 36281440
• Shakowski C, Pham VA, Raines J, Quaife RA, Page RL 2nd. Safety and efficacy of IV theophylline for regadenoson-associated side effect reversal. J Nucl Cardiol. 2022 Jul 7. [Epub ahead of print] PubMed PMID: 35799037
• Edward JA, Cerbin LP, Groves DW, Quaife RA, Hunter KS, Levine BD, Cornwell WK 3rd. Right Ventricular Dysfunction During Endurance Exercise as Determined by Pressure-Volume Analysis. JACC Case Rep. 2022 Nov 2;4(21):1435-1438. PubMed PMID: 36388707
• Sucharov CC, Kao DP, Port JD, Karimpour-Fard A, Quaife RA, Minobe W, Nunley K, Lowes BD, Gilbert EM, Bristow MR. Myocardial microRNAs associated with reverse remodeling in human heart failure. JCI Insight. 2017 Jan 26;2(2):
• Bristow MR, Kao DP, Breathett KK, Altman NL, Gorcsan J 3rd, Gill EA, Lowes BD, Gilbert EM, Quaife RA, Mann DL. Structural and Functional Phenotyping of the Failing Heart: Is the Left Ventricular Ejection Fraction Obsolete? JACC Heart Fail. 2017 Nov;5(11):772-781.
• Søndergaard L, Kasner SE, Rhodes JF, Andersen G, Iversen HK, Nielsen-Kudsk JE, Settergren M, Sjöstrand C, Roine RO, Hildick-Smith D, Spence JD, Thomassen L; Gore REDUCE Clinical Study Investigators. Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke. N Engl J Med. 2017 Sep 14;377(11):1033-1042.
• Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS, Tirschwell DL; RESPECT Investigators. Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke. N Engl J Med. 2017 Sep 14;377(11):1022-1032.
• Myocardial microRNAs associated with reverse remodeling in human heart failure. Sucharov CC, Kao DP, Port JD, Karimpour-Fard A, Quaife RA, Minobe W, Nunley K, Lowes BD, Gilbert EM, Bristow MR. JCI Insight. 2017 Jan 26;2(2):
• Enhanced Radiofrequency Ablation With Magnetically Directed Metallic Nanoparticles. Nguyen DT, Tzou WS, Zheng L, Barham W, Schuller JL, Shillinglaw B, Quaife RA, Sauer WH. Circ Arrhythm Electrophysiol. 2016 May;9(5).
• Clegg SD, Chen SJ, Nijhof N, Kim MS, Salcedo EE, Quaife RA, Messenger JC, Bracken J, Carroll JD. Integrated 3D Echo-X Ray to Optimize Image Guidance for Structural Heart Intervention. JACC Cardiovasc Imaging. 2015 Mar;8(3):371-4. PubMed PMID: 25772840
• The adrenergic system in pulmonary arterial hypertension: bench to bedside (2013 Grover Conference series). Bristow MR, Quaife RA. Pulm Circ. 2015 Sep;5(3):415-23.
• Tropheryma whipplei Endocarditis: A Two-patient Case Series. Borne RT, Babu A, Levi M, Brieke A, Quaife RA. Am J Med. 2015 Dec;128(12):1364-6. doi: 10.1016/j.amjmed.2015.06.053. Epub 2015 Jul 31
• Kim MS, Bracken J, Nijhof N, Salcedo EE, Quaife RA, Messenger JC, Carroll JD. Integrated 3D Echo-X-Ray navigation to predict optimal angiographic deployment projections for TAVR. JACC Cardiovasc Imaging. 2014 Aug;7(8):847-8. PubMed PMID: 25124019
• Moss TJ, Krantz MJ, Zipse MM, Quaife RA, Sauer WH, Messenger JC, Groves BM, Salcedo EE, Schuller JL. Left ventricular systolic function following alcohol septal ablation for symptomatic hypertrophic cardiomyopathy. Am J Cardiol. 2014 Apr 15;113(8):1401-4. PubMed PMID: 24576545
• Quaife RA, Salcedo EE, Carroll JD. Procedural guidance using advance imaging techniques for percutaneous edge-to-edge mitral valve repair. Curr Cardiol Rep. 2014 Feb;16(2):452. PubMed PMID: 24430014
• Jennifer L. Dorosz MD, Brian M. Fonseca MD, Joseph D. Kay MD, Brian B. Graham, Ernesto E. Salcedo MD, Robert A. Quaife MD. A Sinus Venosus Atrial Septal Defect is Diagnosed by Echocardiography with an Unusual Bubble Study. Echocardiography 2013
• Eng MJ, Salcedo EE, Kim M, Quaife RA, Carroll JD. Implementation of real-time three-dimensional transesophageal echocardiography for mitral balloon valvuloplasty. Catheter Cardiovasc Interv. 2013 Nov 15;82(6):994-8.
• Dorosz JL, Fonseca BM, Kay JD, Graham BB, Salcedo EE, Quaife RA. A sinus venosus atrial septal defect is diagnosed by echocardiography with an unusual bubble study. 2013 Jul;30(6):E182-3. doi: 10.1111/echo.12191. Epub 2013.
• Bang TJ, Suby-Long T, Borgstede JP, Quaife R, Pritchard N, Street D, Restauri N. University of colorado radiologist adult contrast reaction smartcard. J Am Coll Radiol. 2013 Jun;10(6):467-9.
• Quaife RA, Salcedo EP, Wolfel EE. Non-compaction cardiomyopathy; underdiagnosed or over diagnosed. Curr Cardiovasc Imaging Rep Oct 2013;doi 10 1007/s 12410-013-9227-z.
• Ruckdeschel ES, Quaife R, Lewkowiez L, Kay J, Sauer WH, Collins KK, Nguyen DT. Preprocedural imaging in patients with transposition of the great arteries facilitates placement of cardiac resynchronization therapy leads. Pacing Clin Electrophysiol. 2013 Dec Dec;10(6):667-78.
• Quaife RA, Salcedo EE, Carroll JD. Procedural Guidance Using Advance Imaging Techniques for Percutaneous Edge-to-Edge Mitral Valve Repair. Curr Cardiol Rep. 2014 Feb;16(2):45.
• Moss TJ, Krantz MJ, Zipse MM, Quaife RA, Sauer WH, Messenger JC, Groves BM, Salcedo EE, Schuller JL. Left ventricular systolic function following alcohol septal ablation for symptomatic hypertrophic cardiomyopathy. Am J Cardiol. 2014 Jan 31. pii: S0002-9149(14)00559-1. doi: 10.1016/j.amjcard.2014.01.417
• Fagan TE, Truong UT, Jone P, Bracken J, Quaife RA, Abu Hazeem AA, Salcedo EE, Fonseca BM. Multimodality 3-dimensional image integration for congenital cardiac catheterization. Texas Heart J (in press).
• Page RL 2nd, Spurck P, Bainbridge JL, Michalek J, Quaife RA. Seizures associated with regadenoson: a case series. J Nucl Cardiol. 2012 Apr;19(2):389-91.
• Chapter 3; Integrated Imaging Modalities in the Cardiac Catheterization Laboratory. In Cardiac Catheterization, Angiography, and Intervention. Baim and Grossman 8th ed Mauro Moscuccim. Lippincott, Williams and Wilkens
• Imaging in Structural Heart Disease in Adult Structural Heart Disease: A Practical Guide for Clinicians. eds Lasala and Rogers
• Clegg S, Chen J, Salcedo E, Quaife R, Carroll J. Integrated 3D Echo X ray Guidance for Structural Heart Disease. ACC 3/2012
• Page RL 2nd, Spurck P, Bainbridge JL, Michalek J, Quaife RA. Seizures associated with regadenoson: A case series. J Nucl Cardiol. 2012 Apr;19(2):389-91
• Feldman T, Foster E, Glower DD, Kar S, Rinaldi MJ, Fail PS, Smalling RW, Siegel R, Rose GA, Engeron E, Loghin C, Trento A, Skipper ER, Fudge T, Letsou GV, Massaro JM, Mauri L; EVEREST II Investigators. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med. 2011 Apr 14;364(15):1395-406.
• Cardiac CT & MRI in Patient Assessment and Procedural Guidence in Structural Heart Disease. In Maual of Adult Structural Heart Disease eds John D Carroll and John C. Webb. Lippincott Williams and Wilkins
• CT and MRI Procedural Planning for Structual Heart Disease Interventions. in Structual Heart Disease Interventions eds John Webb and John D Carroll
• Quaife RA, Chen MY, Jehle A, Groves BM, Carroll JD. Pre-procedural planning for percutaneous atrial septal defect closure: using cardiac computed tomagraphic angiography. J Card Comp Tomo 2010;4;330-8.
• Salcedo EE, Moloo J, Quaife RA, Assessment of Cardiomyopathies. Echocardiography 2010Sep;27:958-66.
• Douglas Borg MD, Alastair D. Robertson PhD, Brian D Lowes MD, Edward P. Ficaro PhD, James R. Corbett MD, Michael Bristow MD, Robert A Quaife MD. Beta-blockers improve myocardial contractile dispersion in patients with non-ischemic cardiomyopathy. Society of Nuclear Medicine Meeting June 2010
• Quaife RA, Borg DJ, Hilpipre N, Wang D. Cardiac CT assessment of congenital heart disease. Atlas of Cardiac CT Angiography 2nd Edition, Eds Ethan Halprin (In Press)
• Robert A. Quaife M.D. and John D. Carroll M.D. CT evaluation of the interatrial septum in atrial septal defectes. Transcatheter Closure of Atrial Septal Defects & Patent Foramen Ovale: A Comprehensive Assessment. Edited by Drs. Ziyad M. Hijazi, Ted Feldman, Mustafa H. Abdullah Al-Qbandi and Horst Sievert (In Press)
• Quaife RA, Borg DJ, Hilpipre N, Wang D. Cardiac CT assessment of congenital heart disease. Clinical Cardiac CT; Anatomy and Function. 2nd Edition, Eds Ethan J. Halpern ThiemeMedical Publishers
• Robert A. Quaife M.D. and John D. Carroll M.D. CT evaluation of the interatrial septum in atrial septal defectes. Transcatheter Closure of Atrial Septal Defects & Patent Foramen Ovale: A Comprehensive Assessment. Edited by Drs. Ziyad M. Hijazi, Ted Feldman, Mustafa H. Abdullah Al-Qbandi and Horst Sievert Cardiotext Publishers LLC.
• Regensteiner JG, Reusch JEB, Quaife RA, Bauer TA, Smith S, Chen MY, Miller T, Groves BM, Wolfel EE. Evidence of cardiac dysfunction during exercise with recently diagnosed, uncomplicated type 2 diabetes: cardiac abnormalities in type 2 Diabetes with exercise. Med Sci Sports Exerc. 2009;41(5):977-84.
• Salcedo EE, Quaife RA, Seres T, Carroll JD. A framework for systematic characterization of the mitral valve by real-time three-dimensional transesophageal echocardiography. J Am Soc Echocardiogr. 2009 Oct;22(10):1087-99.
• Eng MH, Salcedo EE, Quaife RA, Carroll JD. Implementation of real time three-dimensional transesophageal echocardiography in percutaneous mitral balloon valvuloplasty and structural heart disease interventions. Echocardiography. 2009 Sep;26(8):958-66.
• Marvin H. Eng, M.D., Robert A. Quaife, M.D., Ernesto E. Salcedo, M.D., Joseph D. Kay, M.D., John D. Carroll, M.D. Real-Time 3-Dimensional Transesophageal Echocardiogram Guidance of Percutaneous Atrial Septal Defect Closure Reduces Radiation Exposure CRT Meeting 2009
• Cecilia Hirsch, MD, Ernesto Salcedo, MD, Robert Quaife, MD 3-D Transesophageal Echocardiographic Characteristics of The Mitral Annulus and Mitral Leaflets In Patients With Structural Mitral Regurgitation Europeon Society of Echocardiography December 2009
• Regensteiner JG, Reusch JEB, Quaife RA, Bauer TA, Smith S, Chen MY, Miller T, Groves BM, Wolfel EE. Evidence of cardiac dysfunction during exercise with recently diagnosed, uncomplicated type 2 diabetes: cardiac abnormalities in type 2 Diabetes with exercise. Medicine, Science, Exercise, and Sports Medicine
• Left ventricular outflow tract obstruction in the presence of asymmetric septal hypertrophy and accessory mitral valve tissue treated with alcohol septal ablation. Kim MS, Klein AJ, Groves BM, Quaife RA, Salcedo EE. Eur J Echocardiogr. 2008 Sep;9(5):720-4. Epub 2008 Apr 14
• A comparison of echocardiographic modalities to guide structural heart disease interventions. Hudson PA, Eng MH, Kim MS, Quaife RA, Salcedo EE, Carroll JD. J Interv Cardiol. 2008 Dec;21(6):535-46. Epub 2008 Oct 28
• Rapid prototyping: a new tool in understanding and treating structural heart disease. Kim MS, Hansgen AR, Wink O, Quaife RA, Carroll JD. Circulation. 2008 May 6;117(18):2388-94.
• Kim MS, Hansgen AR, Wink O, Quaife RA, Carroll JD. Rapid Prototyping – A New Tool in Understanding and Treating Structural Heart Disease. Circulation (in press)
• Kim MS, Klein AJ, Groves BM, Quaife RA, Salcedo EE. Left Ventricular Outflow Tract Obstruction in the Presence of Asymmetric Septal Hypertrophy and Accessory Mitral Valve Tissue Treated with Alcohol Septal Ablation. European Journal of Echocardiography (accepted for publication)
• Myocardial perfusion and function: single photon emission computed tomography. Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, Druz RS, Ficaro EP, Galt JR, Garg RK, Germano G, Heller GV, Henzlova MJ, Hyun MC, Johnson LL, Mann A, McCallister BD Jr, Quaife RA, Ruddy TD, Sundaram SN, Taillefer R, Ward RP, Mahmarian JJ; American Society of Nuclear Cardiology. J Nucl Cardiol. 2007 Nov-Dec;14(6):e39-60. Review.
• 39. Jehle AB, Chen MY, Giradas M, Gottshall EB, Weinberger HD, Quaife RA. Myocardial delayed contrast enhancement in pulmonary sarcoid patients, association with significant right and left chamber remodeling. J Cardiovasc Mag Res 2007;9:149.
• Quaife RA, Chen MY, Lynch D, Badesch DB, Groves BM, Wolfel E, Robertson AD, Bristow MR, Voelkel NF. Importance of Right Ventricular End-Systolic Regional Wall Stress in Idiopathic Pulmonary Arterial Hypertension: A New Method for Estimation of Right Ventricular Wall Stress Eur J Med Res 2006;11:124-130.
• Voelkel NF, Quaife RA; Leinwand LA; Barst RJ; McGoon MG MD; Meldrum DR; Dupuis J, Long CS; Rubin LJ, MD; Smart FW; Suzuki YJ; Gladwin M; Denholm EM, Gail DB. Right Ventricular Function and Failure: The Need to Know More: Report of a National Heart Lung and Blood Institute Working Group on Cellular and Molecular Mechanisms of Right Heart Failure. Circulation 2006;1883-1891.
• Qutub W, Lewis K, Gonzalez, Quaife R, Russ P, McCarter M. Lymphangiomatosis masquerading as metastatic melanoma. American Surgeon 2006; 72(4):367-370.
• Jone PN, Haak A, Petri N, Ross M, Morgan G, Wiktor DM, Gill E, Quaife RA, Messenger JC, Salcedo EE, Carroll JD. Echocardiography-Fluoroscopy Fusion Imaging for Guidance of Congenital and Structural Heart Disease Interventions. JACC Cardiovasc Imaging. 2019 Jan 9. pii: S1936-878X.

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Radiology - Anschutz Inpatient Pavilion
12605 E. 16th Ave
Basement
Aurora, CO 80045
720-848-1200

UCHealth Radiology - Anschutz Outpatient Pavilion
1635 Aurora Ct
1st Floor
Aurora, CO 80045
720-848-1130

UCHealth Radiology - Lone Tree
9548 Park Meadows Drive
Lone Tree, CO 80124
720-848-2200

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

CU Medicine Cardiology - Cherry Creek Medical Center
100 Cook Street
Suite 412
Denver, CO 80206
720-516-9403

Hospital Affiliation

• University of Colorado Hospital
• UCHealth Highlands Ranch Hospital

Specialty Information

Specialties

• Internal Medicine, Board Certification (1986)
• General Cardiology, Board Certification (1989)
• Nuclear Medicine, Board Certification (1990, 2012)
• Cardiac MRI, Board Certification (2021)
• Echocardiography, Board Certification (2011)
• Cardiac CT, Board Certification (2011)

Conditions & Treatments

• Heart and Circulation
• Radiology - Nuclear Medicine
• Radiology
• Heart and Circulation - Adult Congenital Heart Disease
• Heart and Circulation - Cardiomyopathy
• Heart and Circulation - Coronary Disease
• Heart and Circulation - Heart Attack
• Heart and Circulation - Transcatheter Aortic Valve Replacement (TAVR)
• Heart and Circulation - Angina
• Heart and Circulation - Vascular Malformations
• Radiology - Magnetic Resonance Imaging (MRI)
• Radiology - Nuclear Cardiology and Cardiac CT
• Radiology - Thoracic Imaging
• Heart and Circulation - Congenital Heart Disease
• Heart and Circulation - Hypertrophic Cardiomyopathy
• Heart and Circulation - Structural Heart Disease